Rattus norvegicus

33 known processes

Spr

sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)

Spr biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oxoacid metabolic processGO:00434362900.077
single organism biosynthetic processGO:00447113420.067
organic substance catabolic processGO:19015753160.067
response to inorganic substanceGO:00100353770.066
organic acid metabolic processGO:00060822920.065
neuron differentiationGO:00301823680.060
cellular component assemblyGO:00226073600.054
carboxylic acid metabolic processGO:00197522890.053
catabolic processGO:00090563510.040
response to extracellular stimulusGO:00099913800.039
cellular component biogenesisGO:00440853680.038
response to decreased oxygen levelsGO:00362932370.038
protein phosphorylationGO:00064683450.037
carboxylic acid biosynthetic processGO:0046394830.036
single organism catabolic processGO:00447122830.036
protein complex subunit organizationGO:00718223020.036
neuron developmentGO:00486662860.035
nucleobase containing small molecule metabolic processGO:00550863160.034
response to nutrient levelsGO:00316673700.034
organophosphate metabolic processGO:00196373700.034
cellular amino acid metabolic processGO:00065201070.033
ribose phosphate metabolic processGO:00196932350.032
response to metal ionGO:00100382530.032
positive regulation of nitrogen compound metabolic processGO:00511733340.031
regulation of phosphorus metabolic processGO:00511743490.031
cell projection organizationGO:00300303020.031
response to peptide hormoneGO:00434342780.031
nucleotide metabolic processGO:00091172790.030
cellular ketone metabolic processGO:0042180510.030
macromolecular complex assemblyGO:00650032730.030
cellular catabolic processGO:00442482950.030
nucleoside phosphate metabolic processGO:00067532830.030
regulation of cellular ketone metabolic processGO:0010565270.029
regulation of cellular amine metabolic processGO:003323880.029
macromolecular complex subunit organizationGO:00439333390.029
regulation of cell differentiationGO:00455953200.028
purine containing compound metabolic processGO:00725212530.028
programmed cell deathGO:00125013920.028
regulation of cellular component organizationGO:00511283680.028
neuron projection developmentGO:00311752730.027
monocarboxylic acid metabolic processGO:00327871520.027
response to hypoxiaGO:00016662310.027
regulation of molecular functionGO:00650093980.027
regulation of cell developmentGO:00602842630.027
positive regulation of response to stimulusGO:00485842850.026
lipid metabolic processGO:00066292830.026
response to glucocorticoidGO:00513842230.026
positive regulation of cellular component organizationGO:00511302000.026
regulation of cellular amino acid metabolic processGO:000652120.026
organic acid biosynthetic processGO:0016053830.025
response to nutrientGO:00075842480.025
response to corticosteroidGO:00319602350.025
chemical homeostasisGO:00488782920.025
response to carbohydrateGO:00097431830.025
carbohydrate derivative metabolic processGO:19011353460.024
protein complex assemblyGO:00064612630.024
homeostatic processGO:00425923310.024
cellular amine metabolic processGO:0044106380.024
regulation of protein metabolic processGO:00512462890.024
reproductive processGO:00224143720.023
purine nucleotide metabolic processGO:00061632290.023
transmembrane transportGO:00550854120.023
response to peptideGO:19016522920.023
ion homeostasisGO:00508012120.022
positive regulation of multicellular organismal processGO:00512403870.022
response to woundingGO:00096112540.022
small molecule biosynthetic processGO:00442831240.022
regulation of neurogenesisGO:00507672470.022
ion transmembrane transportGO:00342203650.022
head developmentGO:00603222470.021
amine metabolic processGO:0009308380.021
cellular response to oxygen containing compoundGO:19017013860.021
protein oligomerizationGO:00512591910.021
negative regulation of metabolic processGO:00098923310.021
protein complex biogenesisGO:00702712630.021
organic cyclic compound catabolic processGO:19013611750.021
regulation of neuron differentiationGO:00456642080.021
positive regulation of biosynthetic processGO:00098913190.021
ribonucleotide metabolic processGO:00092592310.020
purine ribonucleotide metabolic processGO:00091502270.020
nucleoside metabolic processGO:00091161790.020
lipid biosynthetic processGO:00086101280.020
response to oxygen levelsGO:00704822650.020
oxidation reduction processGO:00551143040.020
cellular chemical homeostasisGO:00550822470.020
multi organism reproductive processGO:00447032620.020
regulation of neuron projection developmentGO:00109751610.020
cellular response to stressGO:00335542690.020
intracellular signal transductionGO:00355563140.020
anatomical structure morphogenesisGO:00096532980.020
localization of cellGO:00516742020.019
negative regulation of cell proliferationGO:00082851190.019
positive regulation of cellular amine metabolic processGO:003324030.019
response to monosaccharideGO:00342841590.019
cation transportGO:00068123820.019
regulation of phosphate metabolic processGO:00192203490.019
regulation of cellular protein metabolic processGO:00322682670.019
cellular component movementGO:00069282480.019
cellular homeostasisGO:00197252520.019
response to transition metal nanoparticleGO:19902671220.018
regulation of catalytic activityGO:00507903040.018
regulation of cell proliferationGO:00421273590.018
positive regulation of developmental processGO:00510942830.018
central nervous system developmentGO:00074173110.018
metal ion transportGO:00300012890.018
inflammatory responseGO:00069541500.018
cation transmembrane transportGO:00986552630.018
reproductionGO:00000032450.018
blood circulationGO:00080151830.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
regulation of nervous system developmentGO:00519602640.017
carbohydrate derivative catabolic processGO:19011361470.017
wound healingGO:00420601220.017
regulation of phosphorylationGO:00423252480.017
cellular component morphogenesisGO:00329891550.017
carbohydrate metabolic processGO:00059751300.017
response to estrogenGO:00436272320.017
positive regulation of phosphate metabolic processGO:00459372620.016
glycosyl compound metabolic processGO:19016571820.016
multicellular organism reproductionGO:00325042330.016
response to toxic substanceGO:00096361330.016
purine nucleoside metabolic processGO:00422781690.016
response to growth factorGO:00708481890.016
circulatory system processGO:00030131830.016
positive regulation of nucleobase containing compound metabolic processGO:00459353190.016
single organism reproductive processGO:00447022970.016
cellular nitrogen compound catabolic processGO:00442701630.016
chromosome segregationGO:000705920.016
negative regulation of molecular functionGO:00440921330.016
organophosphate catabolic processGO:00464341480.016
macromolecule localizationGO:00330362520.016
brain developmentGO:00074202470.016
single organism organelle organizationGO:19025891800.016
nucleoside phosphate catabolic processGO:19012921400.016
small gtpase mediated signal transductionGO:0007264360.015
regulation of cell projection organizationGO:00313441750.015
organonitrogen compound biosynthetic processGO:19015661670.015
cardiac chamber developmentGO:000320510.015
positive regulation of catalytic activityGO:00430851840.015
regulation of protein phosphorylationGO:00019321830.015
positive regulation of phosphorylationGO:00423271770.015
alpha amino acid metabolic processGO:1901605710.015
positive regulation of phosphorus metabolic processGO:00105622620.015
organonitrogen compound catabolic processGO:19015651790.015
ribonucleoside metabolic processGO:00091191740.015
cation homeostasisGO:00550801950.015
purine ribonucleoside metabolic processGO:00461281680.015
regulation of multicellular organismal developmentGO:20000263760.015
regulation of hormone levelsGO:00108171870.015
cellular cation homeostasisGO:00300031800.015
locomotionGO:00400112370.014
nitrogen compound transportGO:00717052290.014
response to cytokineGO:00340972150.014
organelle organizationGO:00069962660.014
heterocycle catabolic processGO:00467001670.014
heart morphogenesisGO:000300730.014
cellular modified amino acid metabolic processGO:0006575610.014
fatty acid metabolic processGO:0006631990.014
negative regulation of cellular metabolic processGO:00313242810.014
regulation of body fluid levelsGO:0050878900.014
response to glucoseGO:00097491360.014
response to oxidative stressGO:00069791860.014
hexose metabolic processGO:0019318580.014
developmental process involved in reproductionGO:00030061590.014
sex differentiationGO:00075481130.014
small molecule catabolic processGO:0044282590.014
positive regulation of macromolecule biosynthetic processGO:00105572470.014
neuron projection morphogenesisGO:00488121220.014
metal ion homeostasisGO:00550651860.014
cell morphogenesis involved in differentiationGO:00009041190.014
regulation of signal transductionGO:00099663180.014
reproductive system developmentGO:00614581280.014
positive regulation of cellular biosynthetic processGO:00313282950.013
cell growthGO:00160491040.013
cofactor metabolic processGO:0051186950.013
cellular response to external stimulusGO:00714961180.013
negative regulation of neurogenesisGO:0050768780.013
regulation of system processGO:00440572080.013
cellular response to endogenous stimulusGO:00714953770.013
reproductive structure developmentGO:00486081280.013
response to hexoseGO:00097461440.013
positive regulation of cell developmentGO:00107201760.013
response to acid chemicalGO:00011012220.013
proteolysisGO:00065081750.013
inorganic ion transmembrane transportGO:00986602290.013
neurological system processGO:00508772190.013
anterior posterior pattern specificationGO:000995210.013
response to insulinGO:00328681330.013
cellular lipid metabolic processGO:00442552080.013
negative regulation of innate immune responseGO:004582440.013
aromatic compound catabolic processGO:00194391680.013
gonad developmentGO:00084061040.013
multicellular organismal signalingGO:0035637440.013
development of primary sexual characteristicsGO:00451371070.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
rna biosynthetic processGO:00327743800.013
anion transportGO:00068201780.013
positive regulation of signalingGO:00230562700.013
dephosphorylationGO:0016311980.012
transmission of nerve impulseGO:0019226420.012
multicellular organismal reproductive processGO:00486092330.012
carboxylic acid catabolic processGO:0046395490.012
positive regulation of neuron differentiationGO:00456661260.012
cellular response to nitrogen compoundGO:19016992100.012
positive regulation of molecular functionGO:00440932300.012
response to ketoneGO:19016541820.012
synaptic transmissionGO:00072682350.012
sexual reproductionGO:00199531480.012
agingGO:00075682410.012
regulation of apoptotic processGO:00429813350.012
positive regulation of cell projection organizationGO:00313461110.012
gamete generationGO:00072761240.012
neuronal action potentialGO:0019228350.012
regulation of protein modification processGO:00313991940.012
cardiac ventricle developmentGO:000323110.012
organic acid transportGO:00158491160.012
response to alkaloidGO:00432791320.012
response to organophosphorusGO:00466831020.012
response to biotic stimulusGO:00096072260.012
carboxylic acid transportGO:00469421150.012
regulation of ion transportGO:00432692450.012
immune system processGO:00023762040.012
nucleoside triphosphate metabolic processGO:00091411440.012
ras protein signal transductionGO:0007265290.012
centrosome organizationGO:005129710.012
axis specificationGO:000979840.011
positive regulation of cell communicationGO:00106472710.011
glycosyl compound catabolic processGO:19016581260.011
cell part morphogenesisGO:00329901230.011
regulation of cellular localizationGO:00603412630.011
cellular ion homeostasisGO:00068731840.011
monosaccharide metabolic processGO:0005996610.011
apoptotic processGO:00069153810.011
cell motilityGO:00488702020.011
negative regulation of protein metabolic processGO:00512481140.011
cardiovascular system developmentGO:00723581340.011
response to bacteriumGO:00096172000.011
negative regulation of macromolecule metabolic processGO:00106052600.011
negative regulation of cellular component organizationGO:0051129830.011
regulation of membrane potentialGO:00423911100.011
response to vitaminGO:00332731310.011
cellular response to organonitrogen compoundGO:00714171970.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
nucleobase containing compound catabolic processGO:00346551520.011
action potentialGO:0001508540.011
response to external biotic stimulusGO:00432072210.011
regulation of muscle system processGO:0090257790.011
defense responseGO:00069521940.011
intracellular transportGO:00469071850.011
response to purine containing compoundGO:00140741260.011
secretionGO:00469033070.011
actin filament based processGO:0030029860.011
regulation of response to stressGO:00801341260.011
regulation of rna metabolic processGO:00512523910.011
response to estradiolGO:00323551640.010
single organism carbohydrate metabolic processGO:00447231180.010
negative regulation of catalytic activityGO:00430861030.010
positive regulation of protein metabolic processGO:00512471780.010
cellular metal ion homeostasisGO:00068751720.010
purine containing compound catabolic processGO:00725231380.010
purine ribonucleoside catabolic processGO:00461301240.010
positive regulation of nervous system developmentGO:00519621780.010
embryonic pattern specificationGO:000988010.010
g protein coupled receptor signaling pathwayGO:00071862420.010
growthGO:00400071650.010
positive regulation of gene expressionGO:00106282440.010
anion transmembrane transportGO:0098656770.010
male gamete generationGO:0048232990.010
response to molecule of bacterial originGO:00022371940.010

Spr disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013
nervous system diseaseDOID:86300.013
disease of metabolismDOID:001466700.013
inherited metabolic disorderDOID:65500.012
musculoskeletal system diseaseDOID:1700.012