Rattus norvegicus

0 known processes

Akr1c12

aldo-keto reductase family 1, member C12

Akr1c12 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
lipid metabolic processGO:00066292830.408
Rat
carboxylic acid metabolic processGO:00197522890.374
single organism biosynthetic processGO:00447113420.361
Rat
naphthalene metabolic processGO:001893120.295
Rat
organic acid metabolic processGO:00060822920.282
monocarboxylic acid metabolic processGO:00327871520.216
fatty acid metabolic processGO:0006631990.189
oxidation reduction processGO:00551143040.178
Rat
cellular response to peptideGO:19016531330.174
Rat
response to peptideGO:19016522920.174
Rat
response to peptide hormoneGO:00434342780.162
regulation of hormone levelsGO:00108171870.161
Rat
reproductive processGO:00224143720.158
Rat
terpenoid metabolic processGO:0006721370.152
Rat
cellular component biogenesisGO:00440853680.151
drug catabolic processGO:004273710.143
response to nutrient levelsGO:00316673700.142
cellular lipid metabolic processGO:00442552080.126
Rat
cellular hormone metabolic processGO:0034754490.125
Rat
single organism carbohydrate metabolic processGO:00447231180.120
Rat
response to biotic stimulusGO:00096072260.113
oxoacid metabolic processGO:00434362900.111
multi multicellular organism processGO:00447061380.110
Rat
response to external biotic stimulusGO:00432072210.104
response to acid chemicalGO:00011012220.098
Rat
halogenated hydrocarbon metabolic processGO:004219740.098
small molecule biosynthetic processGO:00442831240.096
Rat
cellular catabolic processGO:00442482950.092
lipid biosynthetic processGO:00086101280.091
cellular component assemblyGO:00226073600.085
response to metal ionGO:00100382530.083
diterpenoid metabolic processGO:0016101330.082
Rat
multi organism reproductive processGO:00447032620.081
Rat
retinal metabolic processGO:004257430.080
Rat
fatty acid derivative metabolic processGO:1901568380.076
response to extracellular stimulusGO:00099913800.075
response to inorganic substanceGO:00100353770.074
Rat
exogenous drug catabolic processGO:004273810.072
isoprenoid metabolic processGO:0006720450.070
Rat
protein complex biogenesisGO:00702712630.068
hormone metabolic processGO:0042445690.067
Rat
protein complex subunit organizationGO:00718223020.066
cellular ketone metabolic processGO:0042180510.066
response to glucocorticoidGO:00513842230.064
behaviorGO:00076102050.062
multicellular organism reproductionGO:00325042330.061
Rat
positive regulation of apoptotic processGO:00430651540.058
cellular response to nitrogen compoundGO:19016992100.057
Rat
carbohydrate metabolic processGO:00059751300.057
Rat
response to alkaloidGO:00432791320.057
negative regulation of metabolic processGO:00098923310.055
catabolic processGO:00090563510.054
neuron developmentGO:00486662860.054
secretion by cellGO:00329402480.053
icosanoid metabolic processGO:0006690380.053
nitrogen compound transportGO:00717052290.053
multicellular organismal reproductive processGO:00486092330.053
Rat
positive regulation of programmed cell deathGO:00430681570.053
cellular response to organonitrogen compoundGO:00714171970.052
Rat
organic substance catabolic processGO:19015753160.052
protein homooligomerizationGO:0051260910.052
organic hydroxy compound metabolic processGO:19016151150.052
Rat
response to molecule of bacterial originGO:00022371940.052
lauric acid metabolic processGO:004825240.051
cellular response to peptide hormone stimulusGO:00713751200.051
response to nutrientGO:00075842480.051
unsaturated fatty acid metabolic processGO:0033559390.050
positive regulation of multicellular organismal processGO:00512403870.050
cellular response to ketoneGO:1901655510.050
Rat
protein complex assemblyGO:00064612630.050
toxin catabolic processGO:000940710.049
response to bacteriumGO:00096172000.049
alditol metabolic processGO:001940040.048
Rat
regulation of lipid metabolic processGO:0019216680.048
anion transportGO:00068201780.046
positive regulation of developmental processGO:00510942830.046
sorbitol biosynthetic processGO:000606110.046
Rat
regulation of nervous system developmentGO:00519602640.046
reproductionGO:00000032450.046
Rat
coumarin catabolic processGO:004622630.046
response to ketoneGO:19016541820.046
Rat
response to transition metal nanoparticleGO:19902671220.045
carbohydrate derivative metabolic processGO:19011353460.043
drug metabolic processGO:0017144110.043
c21 steroid hormone metabolic processGO:0008207140.042
secondary metabolic processGO:0019748150.042
regulation of cell differentiationGO:00455953200.042
defense responseGO:00069521940.042
monosaccharide metabolic processGO:0005996610.040
Rat
chlorinated hydrocarbon metabolic processGO:004219640.039
negative regulation of molecular functionGO:00440921330.039
chemical homeostasisGO:00488782920.038
response to oxidative stressGO:00069791860.037
Rat
protein oligomerizationGO:00512591910.037
macromolecular complex assemblyGO:00650032730.037
organonitrogen compound biosynthetic processGO:19015661670.036
cellular response to stressGO:00335542690.036
Rat
regulation of secretion by cellGO:19035302080.036
insecticide metabolic processGO:001714340.036
negative regulation of transportGO:00510511360.036
regulation of multicellular organismal developmentGO:20000263760.035
regenerationGO:00310991630.035
organic acid biosynthetic processGO:0016053830.035
regulation of cellular ketone metabolic processGO:0010565270.035
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.035
organelle organizationGO:00069962660.034
inner medullary collecting duct developmentGO:007206110.034
Rat
regulation of cell growthGO:0001558850.034
alkaloid metabolic processGO:000982030.033
growthGO:00400071650.033
cellular response to corticosteroid stimulusGO:0071384690.033
signal releaseGO:00230611450.033
monocarboxylic acid biosynthetic processGO:0072330480.032
cellular amino acid metabolic processGO:00065201070.032
response to estrogenGO:00436272320.032
Rat
steroid metabolic processGO:0008202730.031
single organism catabolic processGO:00447122830.031
positive regulation of cell developmentGO:00107201760.031
organophosphate metabolic processGO:00196373700.031
collecting duct developmentGO:007204410.030
Rat
lipid catabolic processGO:0016042460.030
circulatory system processGO:00030131830.029
organ regenerationGO:00311001010.029
jak stat cascadeGO:0007259260.029
Rat
secondary metabolite catabolic processGO:009048710.029
cellular response to organic cyclic compoundGO:00714072020.029
monovalent inorganic cation transportGO:00156721720.029
metal ion transportGO:00300012890.029
regulation of molecular functionGO:00650093980.028
central nervous system developmentGO:00074173110.028
Rat
muscle contractionGO:0006936880.028
organic hydroxy compound transportGO:0015850770.027
peptide transportGO:0015833970.027
regulation of cell developmentGO:00602842630.027
response to ethanolGO:00454711620.027
response to corticosteroidGO:00319602350.027
macromolecular complex subunit organizationGO:00439333390.027
heterocycle catabolic processGO:00467001670.027
macromolecule localizationGO:00330362520.026
response to woundingGO:00096112540.026
glutathione transportGO:003463520.026
neurological system processGO:00508772190.026
regulation of apoptotic processGO:00429813350.025
cation transportGO:00068123820.025
neuron projection developmentGO:00311752730.025
regulation of neurogenesisGO:00507672470.025
blood circulationGO:00080151830.025
positive regulation of response to stimulusGO:00485842850.024
Rat
multicellular organismal homeostasisGO:0048871490.024
Rat
organic cyclic compound catabolic processGO:19013611750.024
catecholamine transportGO:0051937370.024
carboxylic acid biosynthetic processGO:0046394830.024
cell projection organizationGO:00300303020.024
programmed cell deathGO:00125013920.024
single organism reproductive processGO:00447022970.024
Rat
transmembrane transportGO:00550854120.024
regulation of secretionGO:00510462240.024
female pregnancyGO:00075651220.023
Rat
response to oxygen levelsGO:00704822650.023
positive regulation of cell deathGO:00109421840.023
positive regulation of cell proliferationGO:00082842490.023
Rat
response to estradiolGO:00323551640.023
alcohol metabolic processGO:0006066770.023
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.023
energy reserve metabolic processGO:0006112250.023
response to cadmium ionGO:0046686350.022
agingGO:00075682410.022
regulation of peptide hormone secretionGO:0090276800.022
negative regulation of gene expressionGO:00106291990.022
vesicle mediated transportGO:00161921810.022
purine containing compound metabolic processGO:00725212530.022
small gtpase mediated signal transductionGO:0007264360.022
positive regulation of biosynthetic processGO:00098913190.022
fatty acid oxidationGO:0019395290.021
response to vitaminGO:00332731310.021
regulation of cellular localizationGO:00603412630.021
naphthalene containing compound metabolic processGO:009042020.021
Rat
glycogen metabolic processGO:0005977230.021
intracellular transportGO:00469071850.021
regulation of cellular component organizationGO:00511283680.021
catecholamine secretionGO:0050432330.021
response to calcium ionGO:0051592590.021
inflammatory responseGO:00069541500.021
primary alcohol metabolic processGO:0034308140.021
Rat
intracellular signal transductionGO:00355563140.021
Rat
single organism behaviorGO:00447081300.021
negative regulation of multicellular organismal processGO:00512412030.021
regulation of neuron projection developmentGO:00109751610.021
energy derivation by oxidation of organic compoundsGO:0015980460.020
response to organophosphorusGO:00466831020.020
gland developmentGO:00487321550.020
response to ddtGO:004668010.020
sensory perceptionGO:00076001010.020
synaptic vesicle amine transportGO:001584230.020
nucleobase containing small molecule metabolic processGO:00550863160.020
positive regulation of cellular biosynthetic processGO:00313282950.019
organic hydroxy compound biosynthetic processGO:1901617510.019
Rat
response to purine containing compoundGO:00140741260.019
regulation of cell projection organizationGO:00313441750.019
biphenyl catabolic processGO:007098020.019
regulation of metal ion transportGO:00109591180.019
amide transportGO:00428861050.019
response to carbohydrateGO:00097431830.019
alditol biosynthetic processGO:001940140.019
Rat
negative regulation of cellular metabolic processGO:00313242810.019
cellular response to methylglyoxalGO:009723810.019
Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.019
positive regulation of nervous system developmentGO:00519621780.018
hormone biosynthetic processGO:0042446250.018
single organism organelle organizationGO:19025891800.018
norepinephrine metabolic processGO:004241530.018
Rat
ion homeostasisGO:00508012120.018
cellular response to extracellular stimulusGO:0031668730.018
positive regulation of cell differentiationGO:00455972170.018
cellular response to oxygen containing compoundGO:19017013860.018
Rat
homeostatic processGO:00425923310.018
Rat
response to starvationGO:0042594590.018
regulation of catecholamine secretionGO:0050433320.018
regulation of response to stressGO:00801341260.018
regulation of neuron differentiationGO:00456642080.018
cellular response to metal ionGO:0071248550.018
response to amineGO:0014075460.018
ribose phosphate metabolic processGO:00196932350.018
divalent metal ion transportGO:00708381320.018
regulation of insulin secretionGO:0050796650.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
cellular response to insulin stimulusGO:0032869810.018
aromatic compound catabolic processGO:00194391680.017
lipid storageGO:001991510.017
response to cytokineGO:00340972150.017
g protein coupled receptor signaling pathwayGO:00071862420.017
organophosphate biosynthetic processGO:00904071430.017
neurotransmitter transportGO:0006836420.017
ion transmembrane transportGO:00342203650.017
protein localizationGO:00081041910.017
response to other organismGO:00517072200.017
response to toxic substanceGO:00096361330.017
glucan metabolic processGO:0044042230.017
head developmentGO:00603222470.017
Rat
amine metabolic processGO:0009308380.017
cofactor metabolic processGO:0051186950.017
protein heterooligomerizationGO:0051291890.017
retinoid metabolic processGO:0001523240.017
Rat
response to molecule of fungal originGO:000223830.016
synaptic transmissionGO:00072682350.016
membrane organizationGO:0061024940.016
positive regulation of gene expressionGO:00106282440.016
negative regulation of peptide hormone secretionGO:0090278300.016
response to decreased oxygen levelsGO:00362932370.016
positive regulation of cellular component organizationGO:00511302000.016
regulation of protein metabolic processGO:00512462890.016
ribonucleotide metabolic processGO:00092592310.016
muscle system processGO:00030121150.016
response to insulinGO:00328681330.016
toxin metabolic processGO:000940490.016
response to ammonium ionGO:0060359710.016
phenol containing compound metabolic processGO:0018958300.016
Rat
lipid localizationGO:0010876620.015
polysaccharide metabolic processGO:0005976250.015
hormone transportGO:00099141210.015
regulation of ion transportGO:00432692450.015
generation of precursor metabolites and energyGO:0006091620.015
regulation of cell activationGO:0050865500.015
positive regulation of cellular amino acid metabolic processGO:004576410.015
single organism intracellular transportGO:19025821660.015
drug transmembrane transportGO:0006855130.015
cell cell signalingGO:00072673350.015
response to activityGO:0014823730.015
negative regulation of innate immune responseGO:004582440.015
regulation of growthGO:00400081050.015
sodium independent organic anion transportGO:004325220.015
regulation of smooth muscle cell proliferationGO:0048660750.015
Rat
divalent inorganic cation transportGO:00725111340.014
cellular nitrogen compound catabolic processGO:00442701630.014
locomotor rhythmGO:004547510.014
positive regulation of protein metabolic processGO:00512471780.014
urea metabolic processGO:001962750.014
response to testosteroneGO:0033574550.014
insulin secretionGO:0030073690.014
peptide secretionGO:0002790860.014
alpha amino acid metabolic processGO:1901605710.014
cellular response to glucocorticoid stimulusGO:0071385680.014
cellular response to hormone stimulusGO:00328702470.014
purine nucleotide metabolic processGO:00061632290.014
response to lipopolysaccharideGO:00324961910.014
hexitol biosynthetic processGO:001940610.014
Rat
positive regulation of cellular amine metabolic processGO:003324030.014
tripeptide transportGO:004293920.014
phenylpropanoid catabolic processGO:004627130.014
cellular response to oxidative stressGO:0034599760.014
Rat
catechol containing compound metabolic processGO:0009712190.014
Rat
negative regulation of cell proliferationGO:00082851190.014
brain developmentGO:00074202470.014
Rat
peptide hormone secretionGO:0030072840.014
cell growthGO:00160491040.014
negative regulation of hormone secretionGO:0046888460.013
positive regulation of signal transductionGO:00099671750.013
Rat
intestinal absorptionGO:005089230.013
amine transportGO:0015837570.013
benzene containing compound metabolic processGO:0042537220.013
nucleic acid templated transcriptionGO:00976593790.013
response to reactive oxygen speciesGO:00003021200.013
Rat
rna metabolic processGO:00160704060.013
cellular amine metabolic processGO:0044106380.013
carbohydrate derivative biosynthetic processGO:19011371240.013
regulation of cell migrationGO:00303341280.013
negative regulation of cell deathGO:00605482290.013
nucleotide metabolic processGO:00091172790.013
cytoplasmic transportGO:00164821150.013
vascular process in circulatory systemGO:0003018960.013
regulation of neuron deathGO:19012141150.013
cellular response to acid chemicalGO:0071229750.013
regulation of signal transductionGO:00099663180.013
Rat
phospholipid metabolic processGO:0006644610.013
organonitrogen compound catabolic processGO:19015651790.013
renal system developmentGO:0072001670.013
Rat
choline transportGO:001587140.013
coenzyme metabolic processGO:0006732860.013
gamete generationGO:00072761240.013
regulation of cellular amino acid metabolic processGO:000652120.012
regulation of homeostatic processGO:00328441010.012
antibiotic transportGO:004289120.012
meiotic cell cycle processGO:190304630.012
lipid modificationGO:0030258520.012
cellular lipid catabolic processGO:0044242370.012
response to fatty acidGO:0070542650.012
nucleoside phosphate metabolic processGO:00067532830.012
purine ribonucleotide metabolic processGO:00091502270.012
positive regulation of neurogenesisGO:00507691650.012
small molecule catabolic processGO:0044282590.012
secretionGO:00469033070.012
positive regulation of ion transportGO:0043270940.012
multicellular organismal signalingGO:0035637440.012
positive regulation of phosphorylationGO:00423271770.012
aspartate family amino acid metabolic processGO:0009066100.012
regulation of cellular amine metabolic processGO:003323880.012
positive regulation of signalingGO:00230562700.012
Rat
positive regulation of catalytic activityGO:00430851840.012
regulation of synaptic transmissionGO:00508041410.012
negative regulation of catalytic activityGO:00430861030.012
cellular ion homeostasisGO:00068731840.012
cation homeostasisGO:00550801950.012
cellular component movementGO:00069282480.012
regulation of peptide secretionGO:0002791820.012
response to axon injuryGO:0048678590.012
regulation of muscle system processGO:0090257790.012
multicellular organism growthGO:003526410.012
neuron differentiationGO:00301823680.011
polyol metabolic processGO:0019751200.011
Rat
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
response to mercury ionGO:0046689150.011
cellular response to mechanical stimulusGO:0071260480.011
dopamine transportGO:0015872180.011
regulation of anatomical structure sizeGO:00900661350.011
hormone secretionGO:00468791150.011
protein processingGO:0016485680.011
response to mineralocorticoidGO:0051385490.011
organic anion transportGO:00157111320.011
negative regulation of cell developmentGO:0010721820.011
response to vitamin eGO:0033197240.011
regulation of peptide transportGO:0090087870.011
vitamin d receptor signaling pathwayGO:007056110.011
positive regulation of molecular functionGO:00440932300.011
4 chlorobiphenyl metabolic processGO:001888010.011
regulation of catalytic activityGO:00507903040.011
response to antibioticGO:0046677390.011
pancreatic stellate cell proliferationGO:007234320.011
positive regulation of macromolecule biosynthetic processGO:00105572470.011
defense response to gram negative bacteriumGO:005082930.011
regulation of blood pressureGO:0008217830.011
chromosome segregationGO:000705920.011
cellular glucan metabolic processGO:0006073230.011
ras protein signal transductionGO:0007265290.011
establishment of vesicle localizationGO:0051650310.011
fluorene metabolic processGO:001891710.011
heart morphogenesisGO:000300730.011
response to hydrogen peroxideGO:0042542890.011
Rat
oxidative demethylationGO:007098920.011
cellular homeostasisGO:00197252520.011
cation transmembrane transportGO:00986552630.011
cellular response to external stimulusGO:00714961180.011
lipid oxidationGO:0034440300.011
positive regulation of secretionGO:00510471400.011
protein import into nucleusGO:0006606350.011
response to herbicideGO:0009635160.010
regulation of response to external stimulusGO:00321011060.010
response to amphetamineGO:0001975250.010
regulation of carbohydrate metabolic processGO:0006109410.010
androgen metabolic processGO:0008209140.010
negative regulation of signalingGO:00230571570.010
maintenance of locationGO:0051235170.010
cell adhesionGO:00071551100.010
cytokine productionGO:0001816610.010
rho protein signal transductionGO:0007266110.010
response to radiationGO:00093141370.010
negative regulation of secretionGO:0051048820.010
calcitriol biosynthetic process from calciolGO:003637820.010
nucleobase containing compound catabolic processGO:00346551520.010
sexual reproductionGO:00199531480.010
polyol biosynthetic processGO:0046173130.010
Rat
cell cell signaling involved in cell fate commitmentGO:004516820.010
transcription dna templatedGO:00063513770.010
carboxylic acid transportGO:00469421150.010
positive regulation of transferase activityGO:0051347810.010

Akr1c12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
hypertensionDOID:1076300.024
vascular diseaseDOID:17800.024
cardiovascular system diseaseDOID:128700.024
essential hypertensionDOID:1082500.024
artery diseaseDOID:005082800.024
disease of anatomical entityDOID:700.024
disease of cellular proliferationDOID:1456600.011