Rattus norvegicus

47 known processes

Rpe65

retinal pigment epithelium 65

Rpe65 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of molecular functionGO:00650093980.243
regulation of phosphate metabolic processGO:00192203490.217
transmembrane transportGO:00550854120.213
response to carbohydrateGO:00097431830.192
single organism biosynthetic processGO:00447113420.170
regulation of signal transductionGO:00099663180.142
ion transmembrane transportGO:00342203650.140
regulation of phosphorus metabolic processGO:00511743490.127
positive regulation of phosphorus metabolic processGO:00105622620.118
response to estrogenGO:00436272320.118
macromolecular complex subunit organizationGO:00439333390.113
intracellular signal transductionGO:00355563140.106
reproductive processGO:00224143720.106
anion transportGO:00068201780.104
organophosphate metabolic processGO:00196373700.103
cellular response to endogenous stimulusGO:00714953770.102
response to inorganic substanceGO:00100353770.098
cation transportGO:00068123820.095
reproductionGO:00000032450.092
neuron differentiationGO:00301823680.089
positive regulation of phosphate metabolic processGO:00459372620.084
regulation of phosphorylationGO:00423252480.084
regulation of programmed cell deathGO:00430673410.082
protein phosphorylationGO:00064683450.082
cation transmembrane transportGO:00986552630.082
response to nutrient levelsGO:00316673700.079
cellular response to organonitrogen compoundGO:00714171970.078
nucleotide metabolic processGO:00091172790.078
positive regulation of response to stimulusGO:00485842850.071
regulation of transcription from rna polymerase ii promoterGO:00063572340.069
multicellular organism reproductionGO:00325042330.068
homeostatic processGO:00425923310.068
response to alkaloidGO:00432791320.067
protein complex subunit organizationGO:00718223020.066
response to hexoseGO:00097461440.065
circadian rhythmGO:0007623880.064
inflammatory responseGO:00069541500.063
cellular response to organic cyclic compoundGO:00714072020.062
brain developmentGO:00074202470.061
agingGO:00075682410.060
purine ribonucleotide metabolic processGO:00091502270.057
oxoacid metabolic processGO:00434362900.057
negative regulation of metabolic processGO:00098923310.055
transcription dna templatedGO:00063513770.055
inorganic ion transmembrane transportGO:00986602290.054
cellular component movementGO:00069282480.054
cellular chemical homeostasisGO:00550822470.054
response to other organismGO:00517072200.054
positive regulation of nitrogen compound metabolic processGO:00511733340.054
regulation of apoptotic processGO:00429813350.053
protein complex assemblyGO:00064612630.053
positive regulation of signal transductionGO:00099671750.053
organic substance catabolic processGO:19015753160.053
positive regulation of gene expressionGO:00106282440.051
carboxylic acid transportGO:00469421150.051
neuron projection developmentGO:00311752730.051
response to biotic stimulusGO:00096072260.051
protein oligomerizationGO:00512591910.050
organic anion transportGO:00157111320.049
carboxylic acid metabolic processGO:00197522890.049
positive regulation of molecular functionGO:00440932300.049
regulation of ion transportGO:00432692450.049
g protein coupled receptor signaling pathwayGO:00071862420.048
regulation of protein modification processGO:00313991940.048
regulation of protein metabolic processGO:00512462890.047
response to light stimulusGO:0009416520.047
regulation of metal ion transportGO:00109591180.047
nucleobase containing small molecule metabolic processGO:00550863160.047
regulation of catalytic activityGO:00507903040.046
regulation of protein phosphorylationGO:00019321830.046
anatomical structure morphogenesisGO:00096532980.045
positive regulation of rna metabolic processGO:00512542030.045
regulation of neuron differentiationGO:00456642080.045
organic acid metabolic processGO:00060822920.044
protein homooligomerizationGO:0051260910.044
regulation of nucleic acid templated transcriptionGO:19035063800.044
protein complex biogenesisGO:00702712630.044
regulation of growthGO:00400081050.044
alcohol metabolic processGO:0006066770.044
negative regulation of apoptotic processGO:00430661810.043
inorganic cation transmembrane transportGO:00986622020.043
regulation of cellular localizationGO:00603412630.043
regulation of cellular protein metabolic processGO:00322682670.043
programmed cell deathGO:00125013920.042
response to cytokineGO:00340972150.042
negative regulation of cell deathGO:00605482290.042
organic hydroxy compound metabolic processGO:19016151150.042
nucleoside phosphate metabolic processGO:00067532830.042
response to bacteriumGO:00096172000.042
rhythmic processGO:00485111560.041
response to lipopolysaccharideGO:00324961910.041
nitrogen compound transportGO:00717052290.041
regulation of cell proliferationGO:00421273590.041
regulation of kinase activityGO:00435491170.041
positive regulation of phosphorylationGO:00423271770.040
cellular component biogenesisGO:00440853680.040
regulation of cell developmentGO:00602842630.038
lipid biosynthetic processGO:00086101280.038
positive regulation of protein metabolic processGO:00512471780.038
positive regulation of neurogenesisGO:00507691650.038
organelle organizationGO:00069962660.038
cellular response to oxygen containing compoundGO:19017013860.037
metal ion transportGO:00300012890.037
growthGO:00400071650.037
macromolecular complex assemblyGO:00650032730.037
multicellular organismal reproductive processGO:00486092330.037
rna biosynthetic processGO:00327743800.036
positive regulation of protein phosphorylationGO:00019341350.036
response to glucocorticoidGO:00513842230.036
regulation of neurogenesisGO:00507672470.036
regulation of hormone levelsGO:00108171870.036
synaptic transmissionGO:00072682350.036
cellular homeostasisGO:00197252520.036
amine metabolic processGO:0009308380.036
cellular response to alkaloidGO:0071312250.036
regulation of neuron projection developmentGO:00109751610.035
purine nucleotide metabolic processGO:00061632290.035
nucleic acid templated transcriptionGO:00976593790.034
positive regulation of macromolecule biosynthetic processGO:00105572470.034
cellular catabolic processGO:00442482950.034
anion transmembrane transportGO:0098656770.034
positive regulation of biosynthetic processGO:00098913190.034
regulation of cellular ketone metabolic processGO:0010565270.034
negative regulation of biosynthetic processGO:00098901680.034
response to estradiolGO:00323551640.033
response to molecule of bacterial originGO:00022371940.033
positive regulation of catalytic activityGO:00430851840.033
positive regulation of intracellular signal transductionGO:19025331380.033
response to extracellular stimulusGO:00099913800.032
carbohydrate derivative metabolic processGO:19011353460.032
positive regulation of rna biosynthetic processGO:19026801970.032
lipid metabolic processGO:00066292830.032
cell cell signalingGO:00072673350.032
single organism reproductive processGO:00447022970.032
positive regulation of signalingGO:00230562700.032
signal transduction by phosphorylationGO:00230141440.031
positive regulation of cellular biosynthetic processGO:00313282950.031
regulation of cellular component organizationGO:00511283680.031
response to monosaccharideGO:00342841590.031
neuron developmentGO:00486662860.031
apoptotic processGO:00069153810.031
positive regulation of cell communicationGO:00106472710.030
rna metabolic processGO:00160704060.030
regulation of rna biosynthetic processGO:20011413810.030
positive regulation of cellular protein metabolic processGO:00322701670.030
positive regulation of nucleobase containing compound metabolic processGO:00459353190.030
regulation of membrane potentialGO:00423911100.030
neuron projection morphogenesisGO:00488121220.030
response to radiationGO:00093141370.030
cellular amino acid metabolic processGO:00065201070.029
heterocycle catabolic processGO:00467001670.029
cellular lipid metabolic processGO:00442552080.029
cellular response to nitrogen compoundGO:19016992100.029
glutamate receptor signaling pathwayGO:0007215430.029
regulation of transcription dna templatedGO:00063553740.029
negative regulation of nitrogen compound metabolic processGO:00511721610.029
protein localizationGO:00081041910.029
ribose phosphate metabolic processGO:00196932350.028
organophosphate biosynthetic processGO:00904071430.028
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.028
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.028
response to acid chemicalGO:00011012220.027
regulation of system processGO:00440572080.027
regulation of mapk cascadeGO:00434081160.027
regulation of rna metabolic processGO:00512523910.027
cellular ketone metabolic processGO:0042180510.026
mapk cascadeGO:00001651400.026
peptidyl tyrosine phosphorylationGO:0018108720.026
peptidyl amino acid modificationGO:00181931260.026
positive regulation of transcription dna templatedGO:00458931970.026
ribonucleotide metabolic processGO:00092592310.026
organophosphate catabolic processGO:00464341480.026
response to purine containing compoundGO:00140741260.026
regulation of anatomical structure sizeGO:00900661350.025
cell projection organizationGO:00300303020.025
positive regulation of nucleic acid templated transcriptionGO:19035081970.025
cellular component assemblyGO:00226073600.025
response to peptideGO:19016522920.025
central nervous system developmentGO:00074173110.025
cellular response to abiotic stimulusGO:0071214850.025
transcription from rna polymerase ii promoterGO:00063662520.025
negative regulation of programmed cell deathGO:00430691830.025
ribonucleoside triphosphate catabolic processGO:00092031220.025
steroid metabolic processGO:0008202730.025
regulation of intracellular signal transductionGO:19025312180.025
cellular amine metabolic processGO:0044106380.024
negative regulation of cellular metabolic processGO:00313242810.024
response to glucoseGO:00097491360.024
neurological system processGO:00508772190.024
regulation of transferase activityGO:00513381230.024
chemical homeostasisGO:00488782920.024
macromolecule localizationGO:00330362520.024
neural precursor cell proliferationGO:0061351230.023
l glutamate importGO:005193820.023
purine nucleotide catabolic processGO:00061951360.023
nucleoside metabolic processGO:00091161790.023
tissue developmentGO:00098882520.023
single organism behaviorGO:00447081300.023
cellular response to stressGO:00335542690.023
activation of protein kinase activityGO:0032147470.023
purine containing compound metabolic processGO:00725212530.023
catabolic processGO:00090563510.023
positive regulation of nervous system developmentGO:00519621780.022
sex differentiationGO:00075481130.022
positive regulation of cell proliferationGO:00082842490.022
regulation of transmembrane transportGO:00347621220.022
developmental process involved in reproductionGO:00030061590.022
response to blue lightGO:000963710.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
cellular nitrogen compound catabolic processGO:00442701630.022
vasoconstrictionGO:0042310540.022
cyclic purine nucleotide metabolic processGO:0052652620.022
negative regulation of gene expressionGO:00106291990.022
regulation of cellular amine metabolic processGO:003323880.022
organonitrogen compound catabolic processGO:19015651790.022
regulation of response to external stimulusGO:00321011060.021
organic cyclic compound catabolic processGO:19013611750.021
response to corticosteroidGO:00319602350.021
positive regulation of protein modification processGO:00314011420.021
positive regulation of transportGO:00510502450.021
response to growth factorGO:00708481890.021
intracellular transportGO:00469071850.021
carbohydrate homeostasisGO:0033500750.020
negative regulation of cellular biosynthetic processGO:00313271610.020
regulation of epithelial cell proliferationGO:0050678490.020
muscle system processGO:00030121150.020
cellular response to hexose stimulusGO:0071331650.020
cell morphogenesisGO:00009021420.020
camp biosynthetic processGO:0006171470.020
cellular response to hormone stimulusGO:00328702470.020
secretionGO:00469033070.020
positive regulation of response to woundingGO:1903036340.020
response to ketoneGO:19016541820.020
regulation of cellular amino acid metabolic processGO:000652120.020
epithelium developmentGO:0060429960.020
single organism catabolic processGO:00447122830.020
b cell differentiationGO:003018320.019
negative regulation of signalingGO:00230571570.019
response to organophosphorusGO:00466831020.019
cellular ion homeostasisGO:00068731840.019
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.019
positive regulation of mapk cascadeGO:0043410920.019
cell part morphogenesisGO:00329901230.019
positive regulation of kinase activityGO:0033674770.019
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193190.019
regulation of hormone secretionGO:00468831060.019
response to ethanolGO:00454711620.019
regulation of cell differentiationGO:00455953200.019
head developmentGO:00603222470.019
cellular protein localizationGO:00346131220.019
reproductive structure developmentGO:00486081280.019
glucose homeostasisGO:0042593750.019
secretion by cellGO:00329402480.019
negative regulation of transcription dna templatedGO:00458921160.018
purine nucleoside metabolic processGO:00422781690.018
cellular response to histamineGO:007142030.018
multicellular organism growthGO:003526410.018
regulation of response to stressGO:00801341260.018
response to ammonium ionGO:0060359710.018
negative regulation of transportGO:00510511360.018
phototransduction visible lightGO:000760320.018
glycosyl compound metabolic processGO:19016571820.018
positive regulation of apoptotic processGO:00430651540.018
response to external biotic stimulusGO:00432072210.018
heart morphogenesisGO:000300730.018
divalent metal ion transportGO:00708381320.018
glandular epithelial cell differentiationGO:000206740.018
monocarboxylic acid metabolic processGO:00327871520.018
positive regulation of protein kinase activityGO:0045860730.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
negative regulation of molecular functionGO:00440921330.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
cell migrationGO:00164771970.017
negative regulation of macromolecule metabolic processGO:00106052600.017
sexual reproductionGO:00199531480.017
response to peptide hormoneGO:00434342780.017
response to mineralocorticoidGO:0051385490.017
response to campGO:0051591910.017
neuron neuron synaptic transmissionGO:0007270600.017
cellular component morphogenesisGO:00329891550.017
regulation of protein kinase activityGO:00458591050.017
small molecule biosynthetic processGO:00442831240.017
endocrine system developmentGO:0035270300.017
negative regulation of cell proliferationGO:00082851190.017
axis specificationGO:000979840.017
peptidyl tyrosine modificationGO:0018212720.017
ribonucleoside metabolic processGO:00091191740.017
cellular response to glucose stimulusGO:0071333650.017
regulation of secretion by cellGO:19035302080.017
positive regulation of cell deathGO:00109421840.017
synaptic transmission gabaergicGO:0051932220.017
regulation of multicellular organismal developmentGO:20000263760.016
hormone metabolic processGO:0042445690.016
gland developmentGO:00487321550.016
blood circulationGO:00080151830.016
cell morphogenesis involved in differentiationGO:00009041190.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
gliogenesisGO:0042063930.016
leukocyte activationGO:0045321760.016
positive regulation of transferase activityGO:0051347810.016
cellular response to carbohydrate stimulusGO:0071322720.016
purine containing compound catabolic processGO:00725231380.016
hormone transportGO:00099141210.016
gastrulationGO:000736920.016
purine ribonucleotide catabolic processGO:00091541360.016
wound healingGO:00420601220.016
ribonucleotide biosynthetic processGO:0009260850.016
cellular response to growth factor stimulusGO:00713631620.016
positive regulation of secretionGO:00510471400.015
response to mechanical stimulusGO:00096121340.015
neuron deathGO:00709971270.015
glycerolipid metabolic processGO:0046486670.015
reproductive system developmentGO:00614581280.015
organic acid transportGO:00158491160.015
potassium ion transportGO:0006813970.015
regulation of nucleotide metabolic processGO:00061401170.015
positive regulation of multicellular organismal processGO:00512403870.015
response to morphineGO:0043278270.015
regulation of secretionGO:00510462240.015
positive regulation of cellular amine metabolic processGO:003324030.015
cell growthGO:00160491040.015
regulation of cellular carbohydrate metabolic processGO:0010675390.015
ribonucleoside triphosphate metabolic processGO:00091991410.015
purine ribonucleoside catabolic processGO:00461301240.015
eye morphogenesisGO:004859240.014
single organism organelle organizationGO:19025891800.014
terpenoid metabolic processGO:0006721370.014
response to hypoxiaGO:00016662310.014
defense responseGO:00069521940.014
signal releaseGO:00230611450.014
muscle contractionGO:0006936880.014
camp metabolic processGO:0046058630.014
nucleobase containing compound catabolic processGO:00346551520.014
regulation of locomotionGO:00400121480.014
carbohydrate derivative catabolic processGO:19011361470.014
cell cycleGO:00070491010.014
cerebellar granule cell precursor proliferationGO:002193010.014
positive regulation of developmental processGO:00510942830.014
regulation of synaptic transmissionGO:00508041410.014
multi organism reproductive processGO:00447032620.014
response to woundingGO:00096112540.014
regulation of blood vessel sizeGO:0050880890.014
actin filament based processGO:0030029860.014
phospholipid metabolic processGO:0006644610.014
purine ribonucleoside metabolic processGO:00461281680.014
enzyme linked receptor protein signaling pathwayGO:00071671160.014
action potentialGO:0001508540.013
response to hydrogen peroxideGO:0042542890.013
activation of mapkk activityGO:0000186180.013
positive regulation of fat cell proliferationGO:007034610.013
cellular response to lipidGO:00713962010.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.013
cell projection morphogenesisGO:00488581230.013
amide transportGO:00428861050.013
aromatic compound catabolic processGO:00194391680.013
regulation of cell projection organizationGO:00313441750.013
developmental growthGO:00485891000.013
response to insulinGO:00328681330.013
regulation of canonical wnt signaling pathwayGO:006082840.013
cellular response to cytokine stimulusGO:00713451270.013
carbohydrate derivative biosynthetic processGO:19011371240.013
sensory perception of painGO:0019233730.012
ras protein signal transductionGO:0007265290.012
response to metal ionGO:00100382530.012
regulation of behaviorGO:0050795610.012
nerve developmentGO:0021675110.012
positive regulation of neuron differentiationGO:00456661260.012
response to fluorideGO:190261730.012
developmental growth involved in morphogenesisGO:0060560330.012
cardiac muscle cell contractionGO:0086003100.012
negative regulation of response to stimulusGO:00485851550.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
regulation of cellular catabolic processGO:00313291010.012
ion homeostasisGO:00508012120.012
nucleoside phosphate biosynthetic processGO:19012931020.012
regulation of transporter activityGO:0032409500.012
proteolysisGO:00065081750.012
spermatogenesisGO:0007283990.012
regulation of neuron deathGO:19012141150.012
cellular glucose homeostasisGO:0001678660.012
cellular response to acid chemicalGO:0071229750.012
small gtpase mediated signal transductionGO:0007264360.012
regulation of nucleotide biosynthetic processGO:0030808470.012
nucleoside phosphate catabolic processGO:19012921400.012
regulation of cellular component movementGO:00512701500.012
negative regulation of innate immune responseGO:004582440.011
positive regulation of growthGO:0045927550.011
adenohypophysis developmentGO:002198420.011
cell type specific apoptotic processGO:00972851340.011
meiotic cell cycle processGO:190304630.011
cellular response to glucocorticoid stimulusGO:0071385680.011
gonad developmentGO:00084061040.011
cellular response to corticosteroid stimulusGO:0071384690.011
monovalent inorganic cation transportGO:00156721720.011
positive regulation of cellular component movementGO:00512721020.011
inositol trisphosphate biosynthetic processGO:003295930.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
male gamete generationGO:0048232990.011
response to toxic substanceGO:00096361330.011
response to nicotineGO:0035094510.011
ribonucleotide catabolic processGO:00092611360.011
response to reactive oxygen speciesGO:00003021200.011
regulation of muscle system processGO:0090257790.011
hormone biosynthetic processGO:0042446250.011
circulatory system developmentGO:00723591340.011
ossificationGO:0001503700.011
regulation of tube sizeGO:0035150890.011
regulation of ion transmembrane transporter activityGO:0032412480.011
metal ion homeostasisGO:00550651860.011
cation homeostasisGO:00550801950.011
protein transportGO:00150311320.011
regulation of response to woundingGO:1903034690.011
response to transition metal nanoparticleGO:19902671220.011
response to histamineGO:003477630.011
cellular response to monosaccharide stimulusGO:0071326670.011
hormone secretionGO:00468791150.011
regulation of cell motilityGO:20001451310.011
cell proliferation in external granule layerGO:002192410.011
regulation of purine nucleotide metabolic processGO:19005421150.010
organonitrogen compound biosynthetic processGO:19015661670.010
regulation of cyclic nucleotide biosynthetic processGO:0030802450.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
cell motilityGO:00488702020.010
respiratory system developmentGO:0060541450.010
positive regulation of cell developmentGO:00107201760.010
epithelial cell differentiationGO:0030855710.010
response to disaccharideGO:0034285100.010
endochondral bone growthGO:000341630.010
carbohydrate metabolic processGO:00059751300.010
regulation of ion transmembrane transportGO:00347651210.010
positive regulation of synaptic vesicle exocytosisGO:200030230.010
positive regulation of ion transportGO:0043270940.010
circadian behaviorGO:0048512240.010
vesicle organizationGO:0016050290.010

Rpe65 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.055
disease of anatomical entityDOID:700.055
sensory system diseaseDOID:005015500.030
disease of metabolismDOID:001466700.015
eye and adnexa diseaseDOID:149200.014
central nervous system diseaseDOID:33100.013