Rattus norvegicus

0 known processes

Defb4

defensin beta 4

(Aliases: Defb2,Defb3)

Defb4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
monocarboxylic acid metabolic processGO:00327871520.596
response to glucocorticoidGO:00513842230.359
response to acid chemicalGO:00011012220.290
cellular lipid metabolic processGO:00442552080.289
oxoacid metabolic processGO:00434362900.288
central nervous system developmentGO:00074173110.226
carboxylic acid metabolic processGO:00197522890.218
protein complex assemblyGO:00064612630.215
response to ionizing radiationGO:0010212590.201
inorganic ion transmembrane transportGO:00986602290.186
neuron differentiationGO:00301823680.183
organic acid metabolic processGO:00060822920.182
icosanoid metabolic processGO:0006690380.172
carboxylic acid transportGO:00469421150.170
organic acid biosynthetic processGO:0016053830.167
response to inorganic substanceGO:00100353770.166
monovalent inorganic cation transportGO:00156721720.158
protein complex biogenesisGO:00702712630.155
response to reactive oxygen speciesGO:00003021200.152
response to nutrientGO:00075842480.151
cellular response to oxygen containing compoundGO:19017013860.147
regulation of molecular functionGO:00650093980.144
response to corticosteroidGO:00319602350.141
response to retinoic acidGO:0032526630.138
organic anion transportGO:00157111320.136
response to purine containing compoundGO:00140741260.132
response to growth factorGO:00708481890.132
reproductive processGO:00224143720.125
response to radiationGO:00093141370.124
response to extracellular stimulusGO:00099913800.124
response to cytokineGO:00340972150.123
response to peptide hormoneGO:00434342780.123
organic acid transportGO:00158491160.119
cellular component biogenesisGO:00440853680.117
fatty acid derivative metabolic processGO:1901568380.116
protein complex subunit organizationGO:00718223020.115
response to oxidative stressGO:00069791860.111
inorganic cation transmembrane transportGO:00986622020.109
lipid biosynthetic processGO:00086101280.108
regulation of membrane potentialGO:00423911100.104
potassium ion transportGO:0006813970.103
small molecule biosynthetic processGO:00442831240.103
organonitrogen compound biosynthetic processGO:19015661670.099
wound healingGO:00420601220.099
cellular component assemblyGO:00226073600.098
ion transmembrane transportGO:00342203650.098
cation transportGO:00068123820.098
fatty acid metabolic processGO:0006631990.097
cellular ketone metabolic processGO:0042180510.096
response to lipopolysaccharideGO:00324961910.096
response to mineralocorticoidGO:0051385490.094
nucleic acid templated transcriptionGO:00976593790.093
negative regulation of rna metabolic processGO:00512531230.092
regulation of protein metabolic processGO:00512462890.090
negative regulation of metabolic processGO:00098923310.088
chemical homeostasisGO:00488782920.088
carboxylic acid biosynthetic processGO:0046394830.086
glial cell differentiationGO:0010001650.086
single organism reproductive processGO:00447022970.083
protein oligomerizationGO:00512591910.081
amine metabolic processGO:0009308380.080
response to molecule of bacterial originGO:00022371940.079
regulation of potassium ion transportGO:0043266290.078
cellular response to growth factor stimulusGO:00713631620.078
anion transportGO:00068201780.078
proteolysisGO:00065081750.077
forebrain developmentGO:0030900980.076
cellular response to endogenous stimulusGO:00714953770.075
macromolecular complex assemblyGO:00650032730.075
cellular response to abiotic stimulusGO:0071214850.072
monocarboxylic acid transportGO:0015718520.070
metal ion transportGO:00300012890.068
reproductive system developmentGO:00614581280.068
response to nicotineGO:0035094510.068
brain developmentGO:00074202470.065
regulation of ion transportGO:00432692450.064
acid secretionGO:0046717480.063
neuron developmentGO:00486662860.063
response to nutrient levelsGO:00316673700.062
lipid localizationGO:0010876620.061
protein homooligomerizationGO:0051260910.058
lipid transportGO:0006869610.057
cell projection organizationGO:00300303020.056
response to peptideGO:19016522920.056
positive regulation of nitrogen compound metabolic processGO:00511733340.056
cellular response to stressGO:00335542690.055
negative regulation of transcription dna templatedGO:00458921160.054
regulation of cellular component movementGO:00512701500.054
regulation of transcription dna templatedGO:00063553740.053
macromolecular complex subunit organizationGO:00439333390.052
cell cell signalingGO:00072673350.050
regulation of cell proliferationGO:00421273590.049
c21 steroid hormone biosynthetic processGO:0006700100.049
lipid metabolic processGO:00066292830.049
negative regulation of macromolecule metabolic processGO:00106052600.049
regulation of protein modification processGO:00313991940.048
agingGO:00075682410.047
catabolic processGO:00090563510.045
cellular response to nitrogen compoundGO:19016992100.045
positive regulation of multicellular organismal processGO:00512403870.044
cellular metal ion homeostasisGO:00068751720.042
multi organism reproductive processGO:00447032620.042
response to mechanical stimulusGO:00096121340.042
response to vitaminGO:00332731310.042
macromolecule localizationGO:00330362520.041
regulation of metal ion transportGO:00109591180.041
leydig cell differentiationGO:003332780.041
neuron projection developmentGO:00311752730.041
response to estrogenGO:00436272320.040
negative regulation of molecular functionGO:00440921330.040
behaviorGO:00076102050.040
positive regulation of cellular component organizationGO:00511302000.039
positive regulation of nucleic acid templated transcriptionGO:19035081970.039
regulation of nucleic acid templated transcriptionGO:19035063800.038
anatomical structure morphogenesisGO:00096532980.038
single organism biosynthetic processGO:00447113420.038
secretion by cellGO:00329402480.037
negative regulation of neuron differentiationGO:0045665620.037
immune system processGO:00023762040.036
organic substance catabolic processGO:19015753160.035
regulation of body fluid levelsGO:0050878900.035
cellular homeostasisGO:00197252520.035
circulatory system processGO:00030131830.035
regulation of secretion by cellGO:19035302080.035
regulation of transporter activityGO:0032409500.035
positive regulation of cell communicationGO:00106472710.034
cellular calcium ion homeostasisGO:00068741600.034
cellular response to acid chemicalGO:0071229750.034
glycerolipid metabolic processGO:0046486670.034
transcription dna templatedGO:00063513770.034
regulation of secretionGO:00510462240.033
cell motilityGO:00488702020.032
potassium ion transmembrane transportGO:0071805710.032
positive regulation of macromolecule biosynthetic processGO:00105572470.032
androgen biosynthetic processGO:0006702100.032
response to fungicideGO:0060992200.031
divalent inorganic cation homeostasisGO:00725071650.031
regulation of cell migrationGO:00303341280.031
diterpenoid metabolic processGO:0016101330.031
muscle system processGO:00030121150.031
positive regulation of nucleobase containing compound metabolic processGO:00459353190.030
response to ethanolGO:00454711620.030
response to woundingGO:00096112540.030
endocytosisGO:0006897840.030
positive regulation of signalingGO:00230562700.029
monocarboxylic acid biosynthetic processGO:0072330480.029
cellular component movementGO:00069282480.029
cellular response to inorganic substanceGO:0071241650.029
negative regulation of gene expressionGO:00106291990.029
fatty acid biosynthetic processGO:0006633330.028
tongue morphogenesisGO:004358730.028
response to hexoseGO:00097461440.028
organic hydroxy compound metabolic processGO:19016151150.028
cyclic nucleotide metabolic processGO:0009187800.028
homeostatic processGO:00425923310.028
oxidation reduction processGO:00551143040.028
cellular response to oxidative stressGO:0034599760.027
regulation of multicellular organismal developmentGO:20000263760.027
positive regulation of protein phosphorylationGO:00019341350.027
ion homeostasisGO:00508012120.027
sodium ion transportGO:0006814820.027
cellular response to biotic stimulusGO:0071216590.027
cellular potassium ion transportGO:0071804720.026
regulation of hormone levelsGO:00108171870.026
organophosphate biosynthetic processGO:00904071430.026
positive regulation of transportGO:00510502450.026
carbohydrate derivative metabolic processGO:19011353460.026
negative regulation of nucleic acid templated transcriptionGO:19035071170.025
negative regulation of catalytic activityGO:00430861030.025
positive regulation of molecular functionGO:00440932300.025
regulation of rna biosynthetic processGO:20011413810.025
cellular amine metabolic processGO:0044106380.025
purine ribonucleotide metabolic processGO:00091502270.025
regulation of hormone secretionGO:00468831060.025
hormone transportGO:00099141210.024
cellular chemical homeostasisGO:00550822470.024
cellular amino acid metabolic processGO:00065201070.024
cellular response to organonitrogen compoundGO:00714171970.024
cellular response to organic cyclic compoundGO:00714072020.024
regulation of neuron differentiationGO:00456642080.024
regulation of cellular ketone metabolic processGO:0010565270.023
purine nucleotide biosynthetic processGO:0006164830.023
head developmentGO:00603222470.023
macromolecule catabolic processGO:0009057580.023
rna metabolic processGO:00160704060.023
response to amino acidGO:0043200750.023
neurological system processGO:00508772190.023
regulation of systemic arterial blood pressureGO:0003073300.023
cellular response to lipopolysaccharideGO:0071222550.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
transcription from rna polymerase ii promoterGO:00063662520.023
cellular response to steroid hormone stimulusGO:0071383930.023
regulation of cellular amine metabolic processGO:003323880.023
rna biosynthetic processGO:00327743800.023
cation transmembrane transportGO:00986552630.023
positive regulation of developmental processGO:00510942830.022
positive regulation of cellular component biogenesisGO:0044089550.022
negative regulation of response to stimulusGO:00485851550.022
cellular divalent inorganic cation homeostasisGO:00725031620.022
response to increased oxygen levelsGO:0036296450.022
response to alkaloidGO:00432791320.022
telencephalon developmentGO:0021537620.022
cellular response to molecule of bacterial originGO:0071219560.022
response to insulinGO:00328681330.022
unsaturated fatty acid metabolic processGO:0033559390.021
hormone biosynthetic processGO:0042446250.021
response to cadmium ionGO:0046686350.021
response to estradiolGO:00323551640.021
response to ketoneGO:19016541820.020
negative regulation of multicellular organismal processGO:00512412030.020
response to external biotic stimulusGO:00432072210.020
negative regulation of macromolecule biosynthetic processGO:00105581480.020
positive regulation of gene expressionGO:00106282440.020
negative regulation of nervous system developmentGO:0051961790.020
cation homeostasisGO:00550801950.020
cell projection morphogenesisGO:00488581230.020
rhythmic processGO:00485111560.020
reproductionGO:00000032450.020
positive regulation of cellular biosynthetic processGO:00313282950.020
synaptic transmissionGO:00072682350.020
transmembrane transportGO:00550854120.019
urogenital system developmentGO:0001655780.019
organophosphate metabolic processGO:00196373700.019
glutamate secretionGO:0014047190.019
male sex differentiationGO:0046661640.019
long chain fatty acid metabolic processGO:0001676320.019
negative regulation of cellular metabolic processGO:00313242810.019
positive regulation of cell proliferationGO:00082842490.019
regulation of cellular amino acid metabolic processGO:000652120.019
cellular hormone metabolic processGO:0034754490.019
negative regulation of signalingGO:00230571570.019
regulation of transmembrane transportGO:00347621220.019
regulation of nucleotide biosynthetic processGO:0030808470.019
reproductive structure developmentGO:00486081280.019
organelle organizationGO:00069962660.019
regulation of system processGO:00440572080.019
secretionGO:00469033070.019
cellular response to lipidGO:00713962010.019
response to vitamin aGO:0033189360.019
regulation of catalytic activityGO:00507903040.019
nucleotide metabolic processGO:00091172790.018
l glutamate importGO:005193820.018
regulation of cellular component organizationGO:00511283680.018
regulation of cell motilityGO:20001451310.018
negative regulation of protein metabolic processGO:00512481140.018
isoprenoid metabolic processGO:0006720450.018
negative regulation of vascular permeabilityGO:004311630.018
nitrogen compound transportGO:00717052290.018
purine containing compound metabolic processGO:00725212530.018
cellular protein localizationGO:00346131220.018
sexual reproductionGO:00199531480.018
response to testosteroneGO:0033574550.018
positive regulation of transcription dna templatedGO:00458931970.018
negative regulation of innate immune responseGO:004582440.018
signal releaseGO:00230611450.018
aromatic compound catabolic processGO:00194391680.018
nucleoside phosphate biosynthetic processGO:19012931020.018
response to hyperoxiaGO:0055093450.017
unsaturated fatty acid biosynthetic processGO:0006636210.017
protein localizationGO:00081041910.017
positive regulation of cellular protein metabolic processGO:00322701670.017
positive regulation of phosphorus metabolic processGO:00105622620.017
regulation of cyclic nucleotide biosynthetic processGO:0030802450.017
cellular response to mechanical stimulusGO:0071260480.017
regulation of muscle system processGO:0090257790.017
positive regulation of phosphate metabolic processGO:00459372620.017
nucleobase containing small molecule metabolic processGO:00550863160.017
organic hydroxy compound biosynthetic processGO:1901617510.017
metal ion homeostasisGO:00550651860.017
developmental process involved in reproductionGO:00030061590.017
cellular response to metal ionGO:0071248550.017
negative regulation of rna biosynthetic processGO:19026791180.017
positive regulation of protein metabolic processGO:00512471780.017
carbohydrate derivative biosynthetic processGO:19011371240.017
protein tetramerizationGO:0051262380.017
multicellular organism reproductionGO:00325042330.017
response to carbohydrateGO:00097431830.017
motor neuron axon guidanceGO:000804510.017
negative regulation of apoptotic processGO:00430661810.017
regulation of catabolic processGO:00098941130.016
positive regulation of purine nucleotide metabolic processGO:1900544910.016
cellular response to reactive oxygen speciesGO:0034614550.016
purine ribonucleotide biosynthetic processGO:0009152810.016
positive regulation of rna metabolic processGO:00512542030.016
positive regulation of catalytic activityGO:00430851840.016
protein maturationGO:0051604680.016
regulation of ion transmembrane transportGO:00347651210.016
organic cyclic compound catabolic processGO:19013611750.016
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.016
regulation of phosphorylationGO:00423252480.016
regulation of apoptotic processGO:00429813350.016
response to fibroblast growth factorGO:0071774290.016
gonad developmentGO:00084061040.016
regulation of signal transductionGO:00099663180.016
membrane hyperpolarizationGO:0060081110.015
ribose phosphate biosynthetic processGO:0046390870.015
regulation of rna metabolic processGO:00512523910.015
icosanoid biosynthetic processGO:0046456180.015
striated muscle contractionGO:0006941440.015
response to activityGO:0014823730.015
glandular epithelial cell differentiationGO:000206740.015
ribonucleotide metabolic processGO:00092592310.015
regulation of cell projection organizationGO:00313441750.015
gamete generationGO:00072761240.015
ribonucleotide biosynthetic processGO:0009260850.015
cellular response to cytokine stimulusGO:00713451270.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
regulation of synaptic transmissionGO:00508041410.015
multi multicellular organism processGO:00447061380.015
pallium developmentGO:0021543420.015
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
regulation of purine nucleotide biosynthetic processGO:1900371460.015
fatty acid transportGO:0015908250.015
spermatogenesisGO:0007283990.014
blood circulationGO:00080151830.014
positive regulation of cellular amine metabolic processGO:003324030.014
enzyme linked receptor protein signaling pathwayGO:00071671160.014
response to corticosteroneGO:0051412400.014
regulation of cellular component biogenesisGO:0044087860.014
regulation of synaptic growth at neuromuscular junctionGO:000858210.014
protein heterooligomerizationGO:0051291890.014
negative regulation of cell proliferationGO:00082851190.014
regulation of anatomical structure sizeGO:00900661350.014
positive regulation of potassium ion transportGO:0043268130.014
positive regulation of protein modification processGO:00314011420.014
vesicle mediated transportGO:00161921810.013
apoptotic processGO:00069153810.013
regulation of nervous system developmentGO:00519602640.013
cell communication by chemical couplingGO:001064320.013
arachidonic acid metabolic processGO:0019369200.013
regulation of tube sizeGO:0035150890.013
androgen metabolic processGO:0008209140.013
positive regulation of purine nucleotide biosynthetic processGO:1900373360.013
negative regulation of neurogenesisGO:0050768780.013
regulation of ion transmembrane transporter activityGO:0032412480.013
regulation of transcription from rna polymerase ii promoterGO:00063572340.013
specification of organ identityGO:001009220.013
response to metal ionGO:00100382530.013
regulation of protein phosphorylationGO:00019321830.013
insulin secretionGO:0030073690.013
nucleoside phosphate metabolic processGO:00067532830.013
positive regulation of rna biosynthetic processGO:19026801970.012
negative regulation of cell communicationGO:00106481580.012
regulation of blood pressureGO:0008217830.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
response to monosaccharideGO:00342841590.012
regulation of transmembrane transporter activityGO:0022898490.012
chemotaxisGO:0006935660.012
negative regulation of cellular protein metabolic processGO:00322691060.012
positive regulation of response to stimulusGO:00485842850.012
circulatory system developmentGO:00723591340.012
positive regulation of ion transportGO:0043270940.012
insecticide metabolic processGO:001714340.012
steroid biosynthetic processGO:0006694480.012
synaptic transmission glutamatergicGO:0035249330.012
protein phosphorylationGO:00064683450.012
taxisGO:0042330670.011
regulation of protein serine threonine kinase activityGO:0071900640.011
phasic smooth muscle contractionGO:001482130.011
actin filament based processGO:0030029860.011
amino acid transportGO:0006865700.011
vascular process in circulatory systemGO:0003018960.011
cellular catabolic processGO:00442482950.011
positive regulation of catabolic processGO:0009896780.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
circadian rhythmGO:0007623880.011
carboxylic acid catabolic processGO:0046395490.011
male gamete generationGO:0048232990.011
regulation of cell developmentGO:00602842630.011
calcium ion homeostasisGO:00550741620.011
regulation of proteolysisGO:0030162660.011
locomotionGO:00400112370.011
progesterone biosynthetic processGO:000670130.011
regulation of programmed cell deathGO:00430673410.011
cellular response to alkaloidGO:0071312250.011
response to other organismGO:00517072200.011
purine nucleoside metabolic processGO:00422781690.011
cytosolic calcium ion homeostasisGO:00514801400.011
localization of cellGO:00516742020.011
response to oxygen levelsGO:00704822650.011
sodium ion transmembrane transportGO:0035725670.011
regulation of transferase activityGO:00513381230.011
long chain fatty acid transportGO:0015909140.011
nucleoside metabolic processGO:00091161790.011
positive regulation of potassium ion transmembrane transportGO:190138140.011
cell cycle processGO:0022402570.011
response to gamma radiationGO:0010332240.011
multicellular organismal reproductive processGO:00486092330.011
response to light stimulusGO:0009416520.011
programmed cell deathGO:00125013920.011
renal system developmentGO:0072001670.011
single organism catabolic processGO:00447122830.011
limbic system developmentGO:0021761380.011
response to biotic stimulusGO:00096072260.011
cellular response to external stimulusGO:00714961180.011
hormone secretionGO:00468791150.011
regulation of cell cycleGO:0051726730.011
positive regulation of biosynthetic processGO:00098913190.011
pancreatic a cell differentiationGO:000331010.011
regulation of cellular localizationGO:00603412630.010
neuron neuron synaptic transmissionGO:0007270600.010
negative regulation of developmental processGO:00510931250.010
response to bacteriumGO:00096172000.010
neuronal action potentialGO:0019228350.010
cellular cation homeostasisGO:00300031800.010
cell migrationGO:00164771970.010
intracellular transportGO:00469071850.010
ribonucleoside triphosphate metabolic processGO:00091991410.010
regulation of blood circulationGO:19035221100.010
grooming behaviorGO:000762540.010
anterior posterior pattern specificationGO:000995210.010
cytoskeleton organizationGO:00070101110.010
male gonad developmentGO:0008584590.010
cellular response to drugGO:0035690300.010
regulation of cellular protein metabolic processGO:00322682670.010
hormone metabolic processGO:0042445690.010
positive regulation of transferase activityGO:0051347810.010
negative regulation of organ growthGO:004662130.010

Defb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.078
respiratory system diseaseDOID:157900.078
lower respiratory tract diseaseDOID:005016100.078
disease of metabolismDOID:001466700.032
inherited metabolic disorderDOID:65500.032
steroid inherited metabolic disorderDOID:170100.032
congenital adrenal hyperplasiaDOID:005081100.032
lipid metabolism disorderDOID:314600.032
nervous system diseaseDOID:86300.022
sensory system diseaseDOID:005015500.022
retinal diseaseDOID:567900.016
eye diseaseDOID:561400.016
eye and adnexa diseaseDOID:149200.016
retinal degenerationDOID:846600.014
retinitis pigmentosaDOID:1058400.014
integumentary system diseaseDOID:1600.011