Rattus norvegicus

20 known processes

Cttn

cortactin

(Aliases: MGC93456,Cttnb)

Cttn biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
golgi vesicle transportGO:0048193220.770
anatomical structure morphogenesisGO:00096532980.703
cell projection organizationGO:00300303020.551
regulation of cell morphogenesisGO:0022604770.548
cytoskeleton organizationGO:00070101110.524
single organism organelle organizationGO:19025891800.448
catabolic processGO:00090563510.443
cellular component morphogenesisGO:00329891550.418
protein complex assemblyGO:00064612630.379
actin filament based processGO:0030029860.375
regulation of cellular component organizationGO:00511283680.350
cell projection morphogenesisGO:00488581230.349
cell morphogenesisGO:00009021420.335
endocytosisGO:0006897840.319
er to golgi vesicle mediated transportGO:0006888100.317
regulation of cell morphogenesis involved in differentiationGO:0010769720.310
neuron projection morphogenesisGO:00488121220.299
neuron projection developmentGO:00311752730.284
cell morphogenesis involved in neuron differentiationGO:00486671060.273
protein complex biogenesisGO:00702712630.262
regulation of cell projection organizationGO:00313441750.257
locomotionGO:00400112370.249
actin cytoskeleton organizationGO:0030036730.235
neuron differentiationGO:00301823680.214
vesicle mediated transportGO:00161921810.213
protein localizationGO:00081041910.198
cellular component assemblyGO:00226073600.198
biological adhesionGO:00226101100.194
intracellular transportGO:00469071850.192
neuron developmentGO:00486662860.188
macromolecular complex assemblyGO:00650032730.174
carbohydrate derivative metabolic processGO:19011353460.166
cellular component biogenesisGO:00440853680.163
regulation of transcription from rna polymerase ii promoterGO:00063572340.154
single organism cellular localizationGO:19025801020.146
single organism intracellular transportGO:19025821660.136
regulation of cell differentiationGO:00455953200.135
establishment of organelle localizationGO:0051656370.133
macromolecule localizationGO:00330362520.127
cellular component movementGO:00069282480.126
regulation of hydrolase activityGO:00513361430.121
regulation of neuron differentiationGO:00456642080.119
dendrite developmentGO:0016358720.118
behaviorGO:00076102050.113
protein transportGO:00150311320.112
membrane organizationGO:0061024940.109
cell cell signalingGO:00072673350.107
dendritic spine organizationGO:0097061120.106
cell cycleGO:00070491010.102
growthGO:00400071650.102
regulation of dendrite developmentGO:0050773590.097
cell morphogenesis involved in differentiationGO:00009041190.095
heart morphogenesisGO:000300730.094
exocytosisGO:0006887600.093
regulation of cell developmentGO:00602842630.092
regulation of neuron projection developmentGO:00109751610.089
actin filament organizationGO:0007015420.088
purine nucleoside monophosphate catabolic processGO:0009128550.088
synaptic growth at neuromuscular junctionGO:005112410.088
nucleoside monophosphate catabolic processGO:0009125560.086
positive regulation of nucleobase containing compound metabolic processGO:00459353190.084
development of primary sexual characteristicsGO:00451371070.083
regulation of actin cytoskeleton organizationGO:0032956300.082
cellular response to stressGO:00335542690.080
positive regulation of cellular component organizationGO:00511302000.080
organic substance catabolic processGO:19015753160.079
cellular macromolecule localizationGO:00707271220.079
purine nucleotide catabolic processGO:00061951360.075
transcription from rna polymerase ii promoterGO:00063662520.074
regulation of anatomical structure morphogenesisGO:00226031410.074
regulation of multicellular organismal developmentGO:20000263760.073
nucleoside catabolic processGO:00091641260.073
single organism membrane organizationGO:0044802740.072
cellular catabolic processGO:00442482950.071
agingGO:00075682410.069
protein phosphorylationGO:00064683450.069
aromatic compound catabolic processGO:00194391680.068
regulation of nervous system developmentGO:00519602640.067
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.066
cell adhesionGO:00071551100.066
secretionGO:00469033070.066
positive regulation of macromolecule biosynthetic processGO:00105572470.065
macromolecular complex subunit organizationGO:00439333390.064
axon developmentGO:0061564960.064
organelle inheritanceGO:004830820.063
positive regulation of nitrogen compound metabolic processGO:00511733340.063
localization of cellGO:00516742020.063
nucleoside triphosphate catabolic processGO:00091431230.061
regulation of actin filament based processGO:0032970420.061
establishment of vesicle localizationGO:0051650310.060
positive regulation of phosphate metabolic processGO:00459372620.057
glycosyl compound catabolic processGO:19016581260.056
central nervous system developmentGO:00074173110.056
negative regulation of cellular component organizationGO:0051129830.055
cellular metal ion homeostasisGO:00068751720.054
regulation of neurogenesisGO:00507672470.054
cytoskeleton dependent cytokinesisGO:006164020.054
multicellular organismal reproductive processGO:00486092330.053
regulation of anatomical structure sizeGO:00900661350.053
positive regulation of cellular protein metabolic processGO:00322701670.053
positive regulation of developmental processGO:00510942830.052
purine nucleoside triphosphate metabolic processGO:00091441410.052
organelle organizationGO:00069962660.051
reproductive processGO:00224143720.051
nucleobase containing small molecule metabolic processGO:00550863160.051
regulation of phosphate metabolic processGO:00192203490.051
nucleobase containing compound catabolic processGO:00346551520.050
purine containing compound catabolic processGO:00725231380.050
head developmentGO:00603222470.050
protein autophosphorylationGO:0046777660.050
regulation of cellular localizationGO:00603412630.049
nucleoside phosphate catabolic processGO:19012921400.049
regulation of secretion by cellGO:19035302080.049
cellular nitrogen compound catabolic processGO:00442701630.049
membrane fusionGO:0061025260.048
positive regulation of cellular amino acid metabolic processGO:004576410.048
protein complex subunit organizationGO:00718223020.047
nucleoside metabolic processGO:00091161790.047
negative regulation of cell differentiationGO:0045596990.046
response to oxidative stressGO:00069791860.045
chromosome segregationGO:000705920.044
positive regulation of rna metabolic processGO:00512542030.044
response to woundingGO:00096112540.044
regulation of actin filament lengthGO:0030832120.044
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.044
establishment of protein localizationGO:00451841410.044
reproductive system developmentGO:00614581280.044
actin nucleationGO:004501020.044
carboxylic acid metabolic processGO:00197522890.043
multicellular organism growthGO:003526410.043
atp catabolic processGO:0006200540.043
ribonucleoside triphosphate metabolic processGO:00091991410.043
vesicle localizationGO:0051648330.043
regulation of vesicle mediated transportGO:0060627810.042
cell part morphogenesisGO:00329901230.042
regulation of stem cell differentiationGO:200073620.041
reproductive structure developmentGO:00486081280.041
ras protein signal transductionGO:0007265290.041
regulation of protein phosphorylationGO:00019321830.040
purine nucleoside triphosphate catabolic processGO:00091461220.040
cytoplasmic transportGO:00164821150.040
negative regulation of nervous system developmentGO:0051961790.040
cellular amino acid metabolic processGO:00065201070.040
positive regulation of cell projection organizationGO:00313461110.039
tissue morphogenesisGO:0048729220.039
nuclear transportGO:0051169490.039
cell migrationGO:00164771970.039
positive regulation of nucleic acid templated transcriptionGO:19035081970.038
locomotor rhythmGO:004547510.037
negative regulation of actin filament polymerizationGO:003083740.037
immune system processGO:00023762040.037
single organism reproductive processGO:00447022970.037
positive regulation of cell differentiationGO:00455972170.037
purine containing compound metabolic processGO:00725212530.036
regulation of actin polymerization or depolymerizationGO:0008064120.036
actin filament cappingGO:005169320.036
neuromuscular processGO:005090520.036
cellular ion homeostasisGO:00068731840.035
cellular amine metabolic processGO:0044106380.035
cell motilityGO:00488702020.035
vesicle fusion with golgi apparatusGO:004828040.035
developmental process involved in reproductionGO:00030061590.035
lipid localizationGO:0010876620.034
regulation of secretionGO:00510462240.034
cellular protein localizationGO:00346131220.034
mesoderm developmentGO:000749820.034
negative regulation of cell developmentGO:0010721820.034
purine ribonucleotide metabolic processGO:00091502270.034
positive regulation of atpase activityGO:003278160.034
positive regulation of transportGO:00510502450.034
regulation of protein modification processGO:00313991940.034
protein import into nucleusGO:0006606350.033
single organism catabolic processGO:00447122830.033
organophosphate metabolic processGO:00196373700.033
cellular protein complex assemblyGO:0043623440.032
cell cycle processGO:0022402570.032
negative regulation of nitrogen compound metabolic processGO:00511721610.032
ribonucleotide catabolic processGO:00092611360.032
adult locomotory behaviorGO:000834440.032
regulation of cell migrationGO:00303341280.032
lysosomal transportGO:000704180.031
response to oxygen levelsGO:00704822650.031
response to axon injuryGO:0048678590.031
regulation of cellular amino acid metabolic processGO:000652120.031
carbohydrate derivative catabolic processGO:19011361470.031
amine metabolic processGO:0009308380.031
positive regulation of transcription dna templatedGO:00458931970.031
homeostatic processGO:00425923310.031
chemical homeostasisGO:00488782920.031
peptidyl tyrosine phosphorylationGO:0018108720.031
reproductionGO:00000032450.030
nucleoside phosphate metabolic processGO:00067532830.030
regulation of cellular amine metabolic processGO:003323880.030
sex differentiationGO:00075481130.030
regulation of cellular component biogenesisGO:0044087860.030
cell growthGO:00160491040.030
single organism nuclear importGO:1902593350.030
ion homeostasisGO:00508012120.030
blood circulationGO:00080151830.030
regulation of actin nucleationGO:005112520.030
purine ribonucleotide catabolic processGO:00091541360.029
negative regulation of neurogenesisGO:0050768780.029
regulation of protein localizationGO:0032880810.029
heterocycle catabolic processGO:00467001670.029
regulation of growthGO:00400081050.029
neurological system processGO:00508772190.029
sensory organ developmentGO:0007423740.029
actin polymerization or depolymerizationGO:0008154140.028
ribonucleoside monophosphate metabolic processGO:0009161880.028
positive regulation of cellular component biogenesisGO:0044089550.028
metal ion homeostasisGO:00550651860.028
axonogenesisGO:0007409710.028
ion transmembrane transportGO:00342203650.027
receptor mediated endocytosisGO:0006898420.027
regulation of endocytosisGO:0030100420.027
positive regulation of hydrolase activityGO:0051345860.027
actin filament polymerizationGO:0030041110.027
regulation of cytoskeleton organizationGO:0051493490.026
positive regulation of cellular biosynthetic processGO:00313282950.026
regulation of cellular component sizeGO:0032535510.026
nucleoside monophosphate metabolic processGO:0009123930.026
circulatory system processGO:00030131830.026
regulation of cellular ketone metabolic processGO:0010565270.026
transmembrane transportGO:00550854120.025
glial cell differentiationGO:0010001650.025
endomembrane system organizationGO:0010256480.025
golgi organizationGO:0007030170.025
cellular chemical homeostasisGO:00550822470.025
regulation of protein kinase activityGO:00458591050.025
purine ribonucleoside triphosphate metabolic processGO:00092051400.025
negative regulation of growthGO:0045926370.025
multicellular organism reproductionGO:00325042330.025
positive regulation of cytoskeleton organizationGO:0051495260.025
circulatory system developmentGO:00723591340.025
neural crest cell developmentGO:001403220.025
developmental growthGO:00485891000.025
asymmetric protein localizationGO:000810520.025
lipid storageGO:001991510.025
muscle structure developmentGO:0061061870.024
regulation of phosphorus metabolic processGO:00511743490.024
organophosphate catabolic processGO:00464341480.024
multi organism reproductive processGO:00447032620.024
purine ribonucleoside monophosphate catabolic processGO:0009169550.023
regulation of transcription dna templatedGO:00063553740.023
positive regulation of multicellular organismal processGO:00512403870.023
positive regulation of actin filament polymerizationGO:003083850.023
cellular cation homeostasisGO:00300031800.023
regulation of nucleotide metabolic processGO:00061401170.023
secretion by cellGO:00329402480.023
regulation of protein targetingGO:1903533280.023
regulation of cell proliferationGO:00421273590.023
positive regulation of gene expressionGO:00106282440.023
regulation of system processGO:00440572080.022
regulation of membrane potentialGO:00423911100.022
negative regulation of multicellular organismal processGO:00512412030.022
sexual reproductionGO:00199531480.022
regulation of catalytic activityGO:00507903040.022
organelle assemblyGO:0070925220.022
atp metabolic processGO:0046034720.022
regulation of protein polymerizationGO:0032271190.022
intracellular signal transductionGO:00355563140.022
rna metabolic processGO:00160704060.022
hematopoietic progenitor cell differentiationGO:000224420.022
organic acid metabolic processGO:00060822920.022
negative regulation of molecular functionGO:00440921330.021
negative regulation of developmental processGO:00510931250.021
purine nucleoside monophosphate metabolic processGO:0009126840.021
regulation of developmental growthGO:0048638450.021
regulation of dendrite morphogenesisGO:0048814330.021
muscle system processGO:00030121150.021
regulation of rna metabolic processGO:00512523910.021
gliogenesisGO:0042063930.021
meiotic cell cycle processGO:190304630.020
regulation of ion transmembrane transportGO:00347651210.020
ribonucleotide metabolic processGO:00092592310.020
purine nucleotide metabolic processGO:00061632290.020
organic cyclic compound catabolic processGO:19013611750.020
regulation of cell motilityGO:20001451310.020
regulation of exocytosisGO:0017157370.020
actin filament depolymerizationGO:003004230.020
peptidyl amino acid modificationGO:00181931260.020
rna biosynthetic processGO:00327743800.019
regulation of synaptic growth at neuromuscular junctionGO:000858210.019
positive regulation of molecular functionGO:00440932300.019
regulation of programmed cell deathGO:00430673410.019
regulation of proteasomal protein catabolic processGO:006113640.019
appendage morphogenesisGO:003510740.019
arp2 3 complex mediated actin nucleationGO:003431420.019
protein polymerizationGO:0051258220.019
cellular homeostasisGO:00197252520.019
intracellular protein transportGO:0006886790.019
positive regulation of purine nucleotide metabolic processGO:1900544910.019
positive regulation of response to external stimulusGO:0032103510.019
negative regulation of rna biosynthetic processGO:19026791180.019
response to cytokineGO:00340972150.018
small gtpase mediated signal transductionGO:0007264360.018
regulation of cellular protein metabolic processGO:00322682670.018
semicircular canal developmentGO:006087210.018
eye developmentGO:0001654500.018
cation homeostasisGO:00550801950.018
protein targeting to membraneGO:0006612110.018
regulation of axonogenesisGO:0050770370.018
synaptic transmissionGO:00072682350.018
regulation of nucleic acid templated transcriptionGO:19035063800.018
regulation of body fluid levelsGO:0050878900.018
regulation of rab protein signal transductionGO:003248330.018
protein localization to organelleGO:0033365570.018
regulation of hormone levelsGO:00108171870.018
establishment of protein localization to organelleGO:0072594440.018
positive regulation of nucleotide metabolic processGO:0045981910.018
regulation of apoptotic processGO:00429813350.018
mitotic spindle organizationGO:000705220.017
positive regulation of cell proliferationGO:00082842490.017
maintenance of locationGO:0051235170.017
response to peptideGO:19016522920.017
regulation of rna biosynthetic processGO:20011413810.017
embryonic pattern specificationGO:000988010.017
positive regulation of organelle organizationGO:0010638480.017
organonitrogen compound catabolic processGO:19015651790.017
smad protein complex assemblyGO:000718310.017
nucleic acid templated transcriptionGO:00976593790.017
purine nucleoside catabolic processGO:00061521240.017
negative regulation of biosynthetic processGO:00098901680.017
arf protein signal transductionGO:003201100.017
nucleotide metabolic processGO:00091172790.017
axis specificationGO:000979840.017
positive regulation of cell motilityGO:2000147970.017
positive regulation of rna biosynthetic processGO:19026801970.017
tissue developmentGO:00098882520.017
nuclear importGO:0051170350.017
regulation of rab gtpase activityGO:003231330.017
protein importGO:0017038370.017
regulation of mitotic sister chromatid separationGO:001096510.017
microtubule based processGO:0007017360.016
muscle cell differentiationGO:0042692520.016
positive regulation of purine nucleotide catabolic processGO:0033123530.016
regulation of kinase activityGO:00435491170.016
nitrogen compound transportGO:00717052290.016
response to external biotic stimulusGO:00432072210.016
rab protein signal transductionGO:003248210.016
neurotransmitter secretionGO:0007269330.016
regulation of cell growthGO:0001558850.016
regulation of synaptic transmissionGO:00508041410.016
purine ribonucleoside monophosphate metabolic processGO:0009167840.016
negative regulation of macromolecule metabolic processGO:00106052600.016
protein targetingGO:0006605610.016
regenerationGO:00310991630.016
positive regulation of cell communicationGO:00106472710.016
negative regulation of metabolic processGO:00098923310.016
programmed cell deathGO:00125013920.016
regulation of molecular functionGO:00650093980.016
hepaticobiliary system developmentGO:0061008900.016
cardiac chamber developmentGO:000320510.015
metaphase anaphase transition of mitotic cell cycleGO:000709110.015
cardiovascular system developmentGO:00723581340.015
vascular process in circulatory systemGO:0003018960.015
spindle organizationGO:000705120.015
dendrite morphogenesisGO:0048813430.015
nucleoside triphosphate metabolic processGO:00091411440.015
plasma membrane organizationGO:0007009170.015
olfactory behaviorGO:004204820.015
signal releaseGO:00230611450.015
positive regulation of response to stimulusGO:00485842850.015
regulation of locomotionGO:00400121480.015
single organism cell adhesionGO:0098602460.015
organelle fusionGO:0048284170.015
regulation of catabolic processGO:00098941130.015
regulation of cell cycleGO:0051726730.015
regulation of behaviorGO:0050795610.015
muscle contractionGO:0006936880.014
response to alkaloidGO:00432791320.014
ribonucleoside triphosphate catabolic processGO:00092031220.014
response to metal ionGO:00100382530.014
protein maturationGO:0051604680.014
regulation of protein transportGO:0051223680.014
single organism behaviorGO:00447081300.014
inorganic cation transmembrane transportGO:00986622020.014
regulation of cellular component movementGO:00512701500.014
purine nucleoside metabolic processGO:00422781690.014
positive regulation of cellular catabolic processGO:0031331710.014
divalent inorganic cation homeostasisGO:00725071650.014
positive regulation of phosphorylationGO:00423271770.014
regulation of protein metabolic processGO:00512462890.014
positive regulation of catabolic processGO:0009896780.014
response to nutrient levelsGO:00316673700.014
protein localization to nucleusGO:0034504390.014
chemosensory behaviorGO:000763520.014
dendritic spine developmentGO:0060996200.014
negative regulation of transportGO:00510511360.013
gonad developmentGO:00084061040.013
positive regulation of nucleotide catabolic processGO:0030813530.013
positive regulation of protein phosphorylationGO:00019341350.013
response to extracellular stimulusGO:00099913800.013
positive regulation of signalingGO:00230562700.013
divalent inorganic cation transportGO:00725111340.013
cellular macromolecular complex assemblyGO:0034622580.013
cellular ketone metabolic processGO:0042180510.013
rho protein signal transductionGO:0007266110.013
response to biotic stimulusGO:00096072260.013
dephosphorylationGO:0016311980.013
cardiac ventricle developmentGO:000323110.013
brain developmentGO:00074202470.013
positive regulation of secretionGO:00510471400.013
activation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:009729610.013
protein oligomerizationGO:00512591910.013
erythrocyte differentiationGO:003021810.013
regulation of organelle organizationGO:0033043800.013
reactive oxygen species biosynthetic processGO:190340980.013
metal ion transportGO:00300012890.012
regulation of homotypic cell cell adhesionGO:003411040.012
regulation of ion transmembrane transporter activityGO:0032412480.012
neurotransmitter transportGO:0006836420.012
transcription dna templatedGO:00063513770.012
leukocyte chemotaxisGO:0030595220.012
positive regulation of biosynthetic processGO:00098913190.012
negative regulation of cell communicationGO:00106481580.012
regulation of notch signaling pathwayGO:000859330.012
organic hydroxy compound metabolic processGO:19016151150.012
mesenchymal to epithelial transitionGO:006023130.012
regulation of endothelial cell differentiationGO:004560140.012
negative regulation of neuron differentiationGO:0045665620.012
negative regulation of rna metabolic processGO:00512531230.012
fatty acid derivative metabolic processGO:1901568380.012
regulation of synaptic plasticityGO:0048167700.012
regulation of canonical wnt signaling pathwayGO:006082840.012
cellular response to unfolded proteinGO:003462020.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
spermatogenesisGO:0007283990.012
negative regulation of cellular metabolic processGO:00313242810.012
apoptotic processGO:00069153810.012
neuron apoptotic processGO:0051402880.012
regulation of transmembrane transportGO:00347621220.012
response to interferon gammaGO:0034341200.012
regulation of receptor mediated endocytosisGO:0048259170.012
regulation of blood circulationGO:19035221100.012
mitotic cell cycleGO:0000278490.012
establishment of protein localization to membraneGO:0090150160.012
macromolecule catabolic processGO:0009057580.012
sequestering of calcium ionGO:005120880.012
negative regulation of transcription dna templatedGO:00458921160.012
oxoacid metabolic processGO:00434362900.011
regulation of phosphorylationGO:00423252480.011
negative regulation of gene expressionGO:00106291990.011
ribose phosphate metabolic processGO:00196932350.011
positive regulation of protein modification processGO:00314011420.011
response to inorganic substanceGO:00100353770.011
regulation of ras gtpase activityGO:0032318320.011
response to hypoxiaGO:00016662310.011
meiotic chromosome segregationGO:004513210.011
protein localization to membraneGO:0072657360.011
neural crest cell migrationGO:000175510.011
rna localizationGO:000640340.011
formation of primary germ layerGO:000170410.011
male gamete generationGO:0048232990.011
tumor necrosis factor mediated signaling pathwayGO:003320940.011
positive regulation of transcription factor import into nucleusGO:004299340.011
regulation of endocrine processGO:0044060210.011
regulation of establishment of protein localizationGO:0070201690.011
anion transportGO:00068201780.011
cellular response to growth factor stimulusGO:00713631620.011
organelle localizationGO:0051640550.011
cardiac muscle contractionGO:0060048270.011
regulation of neurotransmitter levelsGO:0001505420.011
ribonucleoside metabolic processGO:00091191740.011
negative regulation of catalytic activityGO:00430861030.011
positive regulation of chemotaxisGO:0050921230.011
positive regulation of cell developmentGO:00107201760.011
positive regulation of cellular amine metabolic processGO:003324030.011
protein heterooligomerizationGO:0051291890.011
peptidyl tyrosine modificationGO:0018212720.010
regulation of intracellular signal transductionGO:19025312180.010
heart processGO:0003015570.010
gamete generationGO:00072761240.010
cortical actin cytoskeleton organizationGO:003086620.010
regulation of leukocyte migrationGO:0002685240.010
negative regulation of neuron projection developmentGO:0010977460.010
positive regulation of neuron projection developmentGO:0010976990.010
negative regulation of nucleic acid templated transcriptionGO:19035071170.010
positive regulation of dendrite developmentGO:1900006350.010
enzyme linked receptor protein signaling pathwayGO:00071671160.010
hormone transportGO:00099141210.010
regulation of ion transportGO:00432692450.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.010
positive regulation of protein metabolic processGO:00512471780.010
regulation of purine nucleotide catabolic processGO:0033121650.010
negative regulation of cell proliferationGO:00082851190.010

Cttn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.047
disease of cellular proliferationDOID:1456600.042
cancerDOID:16200.034
musculoskeletal system diseaseDOID:1700.026
organ system cancerDOID:005068600.020
connective tissue diseaseDOID:6500.019
sensory system diseaseDOID:005015500.017
central nervous system diseaseDOID:33100.015
disease of metabolismDOID:001466700.011