Rattus norvegicus

32 known processes

Mlc1

megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)

Mlc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
agingGO:00075682410.212
anion transportGO:00068201780.190
response to carbohydrateGO:00097431830.175
carboxylic acid metabolic processGO:00197522890.169
cellular amino acid metabolic processGO:00065201070.160
organic acid transportGO:00158491160.152
organic anion transportGO:00157111320.146
amino acid transportGO:0006865700.140
regulation of cell proliferationGO:00421273590.125
organic acid metabolic processGO:00060822920.109
regulation of secretion by cellGO:19035302080.105
nitrogen compound transportGO:00717052290.104
response to woundingGO:00096112540.103
cellular component movementGO:00069282480.100
oxoacid metabolic processGO:00434362900.085
homeostatic processGO:00425923310.085
cardiovascular system developmentGO:00723581340.085
cation transportGO:00068123820.084
regulation of multicellular organismal developmentGO:20000263760.084
regulation of cellular component organizationGO:00511283680.083
organic substance catabolic processGO:19015753160.081
regulation of synaptic transmissionGO:00508041410.081
regulation of protein metabolic processGO:00512462890.078
rna biosynthetic processGO:00327743800.073
regulation of cellular amine metabolic processGO:003323880.073
regulation of cellular localizationGO:00603412630.071
synaptic transmissionGO:00072682350.071
transcription from rna polymerase ii promoterGO:00063662520.067
defense responseGO:00069521940.066
cellular homeostasisGO:00197252520.063
regulation of cellular protein metabolic processGO:00322682670.062
regulation of anatomical structure morphogenesisGO:00226031410.062
cellular component assemblyGO:00226073600.062
multi organism reproductive processGO:00447032620.061
central nervous system developmentGO:00074173110.060
single organism behaviorGO:00447081300.057
positive regulation of developmental processGO:00510942830.057
regulation of apoptotic processGO:00429813350.056
positive regulation of nitrogen compound metabolic processGO:00511733340.056
signal transduction by phosphorylationGO:00230141440.056
protein phosphorylationGO:00064683450.055
cellular amine metabolic processGO:0044106380.054
regulation of rna metabolic processGO:00512523910.054
amine metabolic processGO:0009308380.054
cell motilityGO:00488702020.054
positive regulation of nervous system developmentGO:00519621780.054
response to ethanolGO:00454711620.053
neuron projection developmentGO:00311752730.053
regulation of secretionGO:00510462240.053
regulation of amine transportGO:0051952540.052
response to decreased oxygen levelsGO:00362932370.052
secretionGO:00469033070.051
head developmentGO:00603222470.051
multicellular organism growthGO:003526410.050
secretion by cellGO:00329402480.049
organonitrogen compound catabolic processGO:19015651790.049
multicellular organismal reproductive processGO:00486092330.049
amine transportGO:0015837570.048
regulation of neuron projection developmentGO:00109751610.048
cell migrationGO:00164771970.048
localization of cellGO:00516742020.048
cell cell signalingGO:00072673350.048
carboxylic acid transportGO:00469421150.048
chemical homeostasisGO:00488782920.047
cellular chemical homeostasisGO:00550822470.047
cellular response to oxygen containing compoundGO:19017013860.047
protein complex assemblyGO:00064612630.046
negative regulation of metabolic processGO:00098923310.046
regulation of transcription dna templatedGO:00063553740.046
positive regulation of secretion by cellGO:19035321280.046
response to glucocorticoidGO:00513842230.046
positive regulation of cell proliferationGO:00082842490.046
rhythmic processGO:00485111560.045
cellular ketone metabolic processGO:0042180510.045
protein oligomerizationGO:00512591910.044
regulation of nucleic acid templated transcriptionGO:19035063800.043
positive regulation of transportGO:00510502450.043
nucleic acid templated transcriptionGO:00976593790.043
protein complex biogenesisGO:00702712630.043
regulation of cellular amino acid metabolic processGO:000652120.042
macromolecular complex assemblyGO:00650032730.042
regulation of neuron differentiationGO:00456642080.042
regulation of cell developmentGO:00602842630.041
response to glucoseGO:00097491360.041
response to transition metal nanoparticleGO:19902671220.040
response to inorganic substanceGO:00100353770.040
positive regulation of multicellular organismal processGO:00512403870.040
negative regulation of programmed cell deathGO:00430691830.039
response to hexoseGO:00097461440.039
response to monosaccharideGO:00342841590.039
reproductive processGO:00224143720.038
regulation of hormone secretionGO:00468831060.038
amide transportGO:00428861050.038
cellular response to stressGO:00335542690.038
cellular component biogenesisGO:00440853680.038
positive regulation of cellular amino acid metabolic processGO:004576410.038
regulation of transcription from rna polymerase ii promoterGO:00063572340.037
response to extracellular stimulusGO:00099913800.036
cell morphogenesis involved in differentiationGO:00009041190.036
positive regulation of cellular protein metabolic processGO:00322701670.036
negative regulation of cellular metabolic processGO:00313242810.036
response to corticosteroidGO:00319602350.036
oligopeptide transportGO:000685740.036
organelle organizationGO:00069962660.035
response to mechanical stimulusGO:00096121340.035
negative regulation of cell proliferationGO:00082851190.034
mapk cascadeGO:00001651400.034
protein complex subunit organizationGO:00718223020.033
neurological system processGO:00508772190.033
regulation of protein modification processGO:00313991940.032
glutamate secretionGO:0014047190.032
positive regulation of neurogenesisGO:00507691650.032
regulation of phosphorylationGO:00423252480.032
regulation of phosphorus metabolic processGO:00511743490.032
macromolecular complex subunit organizationGO:00439333390.031
gliogenesisGO:0042063930.031
brain developmentGO:00074202470.031
epithelial cell proliferationGO:0050673540.031
developmental growthGO:00485891000.030
response to metal ionGO:00100382530.030
regulation of organic acid transportGO:0032890350.030
negative regulation of multicellular organismal processGO:00512412030.030
regulation of peptide transportGO:0090087870.030
macromolecule localizationGO:00330362520.030
positive regulation of cellular biosynthetic processGO:00313282950.030
astrocyte developmentGO:001400240.030
response to acid chemicalGO:00011012220.030
positive regulation of cellular amine metabolic processGO:003324030.029
regulation of programmed cell deathGO:00430673410.029
circulatory system developmentGO:00723591340.029
positive regulation of signalingGO:00230562700.029
cell morphogenesis involved in neuron differentiationGO:00486671060.029
intracellular signal transductionGO:00355563140.028
multicellular organism reproductionGO:00325042330.028
regulation of molecular functionGO:00650093980.027
single organism catabolic processGO:00447122830.027
locomotionGO:00400112370.027
transcription dna templatedGO:00063513770.027
negative regulation of apoptotic processGO:00430661810.027
anatomical structure morphogenesisGO:00096532980.026
blood circulationGO:00080151830.026
response to ketoneGO:19016541820.026
regulation of locomotionGO:00400121480.026
regulation of cellular ketone metabolic processGO:0010565270.026
response to temperature stimulusGO:0009266940.026
regulation of rna biosynthetic processGO:20011413810.026
negative regulation of cell deathGO:00605482290.026
positive regulation of nucleobase containing compound metabolic processGO:00459353190.026
regulation of neurogenesisGO:00507672470.025
protein localizationGO:00081041910.025
neurotransmitter transportGO:0006836420.025
multi multicellular organism processGO:00447061380.025
catabolic processGO:00090563510.025
regulation of signal transductionGO:00099663180.025
cellular amino acid biosynthetic processGO:0008652320.025
cellular component morphogenesisGO:00329891550.025
regulation of cell motilityGO:20001451310.025
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.024
negative regulation of cell differentiationGO:0045596990.024
negative regulation of transportGO:00510511360.024
positive regulation of cell developmentGO:00107201760.024
tissue developmentGO:00098882520.024
positive regulation of cellular component organizationGO:00511302000.024
negative regulation of signalingGO:00230571570.024
negative regulation of cell developmentGO:0010721820.024
organophosphate metabolic processGO:00196373700.024
regulation of tube sizeGO:0035150890.024
positive regulation of catalytic activityGO:00430851840.024
response to estradiolGO:00323551640.023
regulation of response to woundingGO:1903034690.023
cellular response to growth factor stimulusGO:00713631620.023
cellular response to endogenous stimulusGO:00714953770.023
response to peptide hormoneGO:00434342780.023
regulation of ion transportGO:00432692450.023
immune system processGO:00023762040.023
carbohydrate homeostasisGO:0033500750.023
regulation of protein phosphorylationGO:00019321830.023
response to estrogenGO:00436272320.023
organic hydroxy compound metabolic processGO:19016151150.023
regulation of anatomical structure sizeGO:00900661350.023
response to nutrientGO:00075842480.022
regulation of nervous system developmentGO:00519602640.022
regulation of cell differentiationGO:00455953200.022
negative regulation of gene expressionGO:00106291990.022
negative regulation of neurogenesisGO:0050768780.022
sexual reproductionGO:00199531480.022
positive regulation of protein modification processGO:00314011420.022
response to alkaloidGO:00432791320.022
negative regulation of protein metabolic processGO:00512481140.022
negative regulation of developmental processGO:00510931250.022
sensory organ developmentGO:0007423740.022
positive regulation of phosphorus metabolic processGO:00105622620.022
behaviorGO:00076102050.022
negative regulation of phosphorus metabolic processGO:0010563800.022
rna metabolic processGO:00160704060.022
cellular ion homeostasisGO:00068731840.022
cellular response to external stimulusGO:00714961180.021
ion transmembrane transportGO:00342203650.021
reproductionGO:00000032450.021
dicarboxylic acid transportGO:0006835340.021
regenerationGO:00310991630.021
metal ion transportGO:00300012890.021
positive regulation of response to stimulusGO:00485842850.021
programmed cell deathGO:00125013920.021
axon developmentGO:0061564960.021
circulatory system processGO:00030131830.021
response to campGO:0051591910.021
regulation of cell migrationGO:00303341280.021
response to hypoxiaGO:00016662310.021
regulation of cell projection organizationGO:00313441750.021
positive regulation of cell communicationGO:00106472710.020
regulation of response to stressGO:00801341260.020
response to nutrient levelsGO:00316673700.020
growthGO:00400071650.020
regulation of phosphate metabolic processGO:00192203490.020
positive regulation of rna metabolic processGO:00512542030.020
positive regulation of transcription dna templatedGO:00458931970.020
cellular nitrogen compound catabolic processGO:00442701630.020
wound healingGO:00420601220.020
cell projection organizationGO:00300303020.020
ion homeostasisGO:00508012120.019
negative regulation of molecular functionGO:00440921330.019
purine containing compound metabolic processGO:00725212530.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.019
signal releaseGO:00230611450.019
neuron developmentGO:00486662860.019
cellular response to organonitrogen compoundGO:00714171970.018
positive regulation of secretionGO:00510471400.018
neurotransmitter uptakeGO:000150430.018
negative regulation of nervous system developmentGO:0051961790.018
g protein coupled receptor signaling pathwayGO:00071862420.018
neuron differentiationGO:00301823680.018
response to purine containing compoundGO:00140741260.018
regulation of anion transportGO:0044070430.018
renal sodium excretionGO:0035812200.018
positive regulation of apoptotic processGO:00430651540.018
hepaticobiliary system developmentGO:0061008900.018
female pregnancyGO:00075651220.018
regulation of hydrolase activityGO:00513361430.018
organic acid biosynthetic processGO:0016053830.018
negative regulation of cellular protein metabolic processGO:00322691060.017
amino acid transmembrane transportGO:0003333330.017
cellular response to nitrogen compoundGO:19016992100.017
sensory perception of painGO:0019233730.017
regulation of response to external stimulusGO:00321011060.017
regulation of catalytic activityGO:00507903040.017
response to axon injuryGO:0048678590.017
positive regulation of cell migrationGO:0030335960.017
ovulation cycle processGO:0022602500.017
multicellular organismal homeostasisGO:0048871490.017
gland developmentGO:00487321550.017
peptide secretionGO:0002790860.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
regulation of inflammatory responseGO:0050727480.017
negative regulation of catalytic activityGO:00430861030.017
neural crest cell differentiationGO:001403320.017
positive regulation of macromolecule biosynthetic processGO:00105572470.017
positive regulation of rna biosynthetic processGO:19026801970.017
glucose homeostasisGO:0042593750.017
alpha amino acid metabolic processGO:1901605710.017
regulation of neurotransmitter uptakeGO:005158010.016
proteolysisGO:00065081750.016
hormone secretionGO:00468791150.016
anion transmembrane transportGO:0098656770.016
lipid metabolic processGO:00066292830.016
vesicle mediated transportGO:00161921810.016
learning or memoryGO:0007611900.016
positive regulation of molecular functionGO:00440932300.016
regulation of neurological system processGO:0031644430.016
developmental process involved in reproductionGO:00030061590.016
positive regulation of phosphorylationGO:00423271770.016
response to heatGO:0009408600.015
protein homooligomerizationGO:0051260910.015
regulation of peptide secretionGO:0002791820.015
regulation of amino acid transportGO:0051955250.015
response to growth factorGO:00708481890.015
negative regulation of macromolecule metabolic processGO:00106052600.015
regulation of intracellular signal transductionGO:19025312180.015
glial cell differentiationGO:0010001650.015
protein maturationGO:0051604680.015
secretion by tissueGO:0032941370.015
small molecule biosynthetic processGO:00442831240.015
positive regulation of biosynthetic processGO:00098913190.015
negative regulation of neuron differentiationGO:0045665620.015
negative regulation of signal transductionGO:0009968830.015
monovalent inorganic cation transportGO:00156721720.015
positive regulation of protein phosphorylationGO:00019341350.014
reactive nitrogen species metabolic processGO:200105710.014
inflammatory responseGO:00069541500.014
heterocycle catabolic processGO:00467001670.014
negative regulation of cell communicationGO:00106481580.014
carboxylic acid biosynthetic processGO:0046394830.014
response to cocaineGO:0042220390.014
regulation of epithelial cell proliferationGO:0050678490.014
vascular process in circulatory systemGO:0003018960.014
response to peptideGO:19016522920.014
gamete generationGO:00072761240.014
cellular response to acid chemicalGO:0071229750.014
mesoderm developmentGO:000749820.014
catecholamine transportGO:0051937370.014
regulation of cell growthGO:0001558850.014
peptidyl amino acid modificationGO:00181931260.013
organic cyclic compound catabolic processGO:19013611750.013
neural crest cell migrationGO:000175510.013
cation homeostasisGO:00550801950.013
nucleobase containing small molecule metabolic processGO:00550863160.013
response to cytokineGO:00340972150.013
cellular amino acid catabolic processGO:0009063210.013
peptide transportGO:0015833970.013
regulation of vasculature developmentGO:1901342440.013
positive regulation of neuron differentiationGO:00456661260.013
positive regulation of protein metabolic processGO:00512471780.013
regulation of neuronal synaptic plasticityGO:0048168310.013
heart morphogenesisGO:000300730.013
positive regulation of cell differentiationGO:00455972170.013
reactive oxygen species biosynthetic processGO:190340980.013
positive regulation of cell deathGO:00109421840.013
reproductive structure developmentGO:00486081280.013
regulation of cell morphogenesisGO:0022604770.013
regulation of peptide hormone secretionGO:0090276800.013
intracellular transportGO:00469071850.012
neuron deathGO:00709971270.012
vitamin transportGO:0051180140.012
cell cycleGO:00070491010.012
vasculature developmentGO:0001944700.012
regulation of protein kinase activityGO:00458591050.012
regulation of neuron deathGO:19012141150.012
action potentialGO:0001508540.012
regulation of neurotransmitter levelsGO:0001505420.012
calcium ion homeostasisGO:00550741620.012
cellular response to lipidGO:00713962010.012
regulation of system processGO:00440572080.012
response to bacteriumGO:00096172000.012
nucleobase containing compound catabolic processGO:00346551520.012
regulation of transferase activityGO:00513381230.012
response to insulinGO:00328681330.012
axis specificationGO:000979840.012
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.012
cellular response to cytokine stimulusGO:00713451270.012
cellular catabolic processGO:00442482950.012
cellular response to extracellular stimulusGO:0031668730.012
cellular cation homeostasisGO:00300031800.012
monocarboxylic acid metabolic processGO:00327871520.012
negative regulation of amine transportGO:0051953240.012
regulation of catabolic processGO:00098941130.012
cellular response to hormone stimulusGO:00328702470.012
hormone metabolic processGO:0042445690.012
eye developmentGO:0001654500.012
gonad developmentGO:00084061040.012
metal ion homeostasisGO:00550651860.012
positive regulation of gene expressionGO:00106282440.012
regulation of kinase activityGO:00435491170.012
single organism intracellular transportGO:19025821660.011
circadian rhythmGO:0007623880.011
multicellular organismal signalingGO:0035637440.011
blood vessel morphogenesisGO:0048514580.011
purine nucleotide catabolic processGO:00061951360.011
single organism reproductive processGO:00447022970.011
positive regulation of neuron projection developmentGO:0010976990.011
carbohydrate derivative metabolic processGO:19011353460.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
angiotensin mediated drinking behaviorGO:000305120.011
carbohydrate metabolic processGO:00059751300.011
sex differentiationGO:00075481130.011
ras protein signal transductionGO:0007265290.011
response to oxidative stressGO:00069791860.011
cell fate determinationGO:000170920.011
nucleoside metabolic processGO:00091161790.011
regulation of angiogenesisGO:0045765390.011
negative regulation of cellular component organizationGO:0051129830.011
single organism organelle organizationGO:19025891800.011
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.011
sensory perceptionGO:00076001010.011
muscle system processGO:00030121150.011
positive regulation of saliva secretionGO:004687830.011
muscle cell proliferationGO:0033002840.011
isoprenoid metabolic processGO:0006720450.011
liver developmentGO:0001889900.011
protein processingGO:0016485680.011
response to other organismGO:00517072200.011
nucleoside triphosphate metabolic processGO:00091411440.010
cellular lipid metabolic processGO:00442552080.010
chemosensory behaviorGO:000763520.010
axonogenesisGO:0007409710.010
phosphatidylinositol dephosphorylationGO:004685640.010
negative regulation of response to stimulusGO:00485851550.010
defense response to gram negative bacteriumGO:005082930.010
regulation of body fluid levelsGO:0050878900.010
glutamate receptor signaling pathwayGO:0007215430.010
regulation of synaptic plasticityGO:0048167700.010
regulation of vasoconstrictionGO:0019229440.010
cellular response to nutrient levelsGO:0031669600.010
positive regulation of blood circulationGO:1903524650.010
forebrain developmentGO:0030900980.010
cation transmembrane transportGO:00986552630.010
spinal cord developmentGO:0021510270.010
salivary gland developmentGO:000743130.010
positive regulation of synaptic transmissionGO:0050806620.010

Mlc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.026
nervous system diseaseDOID:86300.026
sensory system diseaseDOID:005015500.014
cerebral degenerationDOID:144300.013
central nervous system diseaseDOID:33100.013
brain diseaseDOID:93600.013
disease of metabolismDOID:001466700.011
inherited metabolic disorderDOID:65500.011