IMP: Integrative Multi-species Prediction

Rattus norvegicus

2 known processes

Ugt2b37

UDP-glucuronosyltransferase 2 family, member 37

RGD: 3937
Entrez: 29623
UniProtKB: F1M7N8

Process Predictions
Disease Predictions

Ugt2b37 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
chlorinated hydrocarbon metabolic process	GO:0042196	4	0.937	Rat
halogenated hydrocarbon metabolic process	GO:0042197	4	0.826	Rat
biphenyl catabolic process	GO:0070980	2	0.738	Rat
response to xenobiotic stimulus	GO:0009410	23	0.641	Rat
steroid catabolic process	GO:0006706	5	0.486	Rat
cellular response to xenobiotic stimulus	GO:0071466	19	0.438	Rat
cellular response to corticosteroid stimulus	GO:0071384	69	0.354	Rat
coumarin catabolic process	GO:0046226	3	0.353	Rat
hepaticobiliary system development	GO:0061008	90	0.303	Rat
response to peptide	GO:1901652	292	0.283	Rat
alkaloid metabolic process	GO:0009820	3	0.281
cellular response to organonitrogen compound	GO:0071417	197	0.273	Rat
cellular response to lipid	GO:0071396	201	0.267	Rat
cellular response to peptide	GO:1901653	133	0.253	Rat
hormone catabolic process	GO:0042447	2	0.249	Rat
liver development	GO:0001889	90	0.230	Rat
response to nutrient	GO:0007584	248	0.225	Rat
trichloroethylene metabolic process	GO:0018979	1	0.213
gland development	GO:0048732	155	0.212	Rat
cellular amino acid metabolic process	GO:0006520	107	0.205
xenobiotic metabolic process	GO:0006805	19	0.192	Rat
cellular response to endogenous stimulus	GO:0071495	377	0.190	Rat
lipid metabolic process	GO:0006629	283	0.189	Rat
phenylpropanoid catabolic process	GO:0046271	3	0.186	Rat
response to glucocorticoid	GO:0051384	223	0.186	Rat
response to nutrient levels	GO:0031667	370	0.184	Rat
oxoacid metabolic process	GO:0043436	290	0.179
response to peptide hormone	GO:0043434	278	0.172	Rat
catabolic process	GO:0009056	351	0.171	Rat
cellular response to oxygen containing compound	GO:1901701	386	0.167	Rat
cellular response to peptide hormone stimulus	GO:0071375	120	0.158	Rat
response to cesium ion	GO:0010164	2	0.154
carboxylic acid metabolic process	GO:0019752	289	0.149
organic acid metabolic process	GO:0006082	292	0.143
cellular response to alcohol	GO:0097306	87	0.138	Rat
cellular response to testosterone stimulus	GO:0071394	5	0.136	Rat
icosanoid metabolic process	GO:0006690	38	0.133
single organism catabolic process	GO:0044712	283	0.130	Rat
response to lipopolysaccharide	GO:0032496	191	0.126	Rat
4 chlorobiphenyl metabolic process	GO:0018880	1	0.123	Rat
cellular response to growth hormone stimulus	GO:0071378	6	0.122	Rat
cellular hormone metabolic process	GO:0034754	49	0.120	Rat
naphthalene metabolic process	GO:0018931	2	0.120
steroid metabolic process	GO:0008202	73	0.120	Rat
cellular response to organic cyclic compound	GO:0071407	202	0.117	Rat
response to organophosphorus	GO:0046683	102	0.116
aromatic compound catabolic process	GO:0019439	168	0.115	Rat
aging	GO:0007568	241	0.109
cellular response to steroid hormone stimulus	GO:0071383	93	0.104	Rat
calcitriol biosynthetic process from calciol	GO:0036378	2	0.103
nicotine metabolic process	GO:0018933	1	0.103
response to metal ion	GO:0010038	253	0.101
cellular response to hormone stimulus	GO:0032870	247	0.100	Rat
response to corticosteroid	GO:0031960	235	0.096	Rat
sulfur compound metabolic process	GO:0006790	70	0.095
cellular response to glucocorticoid stimulus	GO:0071385	68	0.094	Rat
xenobiotic catabolic process	GO:0042178	7	0.089	Rat
4 nitrophenol metabolic process	GO:0018960	1	0.089
response to ethanol	GO:0045471	162	0.089	Rat
cellular response to nitrogen compound	GO:1901699	210	0.088	Rat
response to extracellular stimulus	GO:0009991	380	0.087	Rat
response to other organism	GO:0051707	220	0.086	Rat
female pregnancy	GO:0007565	122	0.085
organic cyclic compound catabolic process	GO:1901361	175	0.081	Rat
oxidation reduction process	GO:0055114	304	0.080
lipid catabolic process	GO:0016042	46	0.076	Rat
organ regeneration	GO:0031100	101	0.075	Rat
response to molecule of bacterial origin	GO:0002237	194	0.073	Rat
regulation of system process	GO:0044057	208	0.072
naphthalene containing compound metabolic process	GO:0090420	2	0.072
organic hydroxy compound metabolic process	GO:1901615	115	0.069
response to ketone	GO:1901654	182	0.067	Rat
response to biotic stimulus	GO:0009607	226	0.067	Rat
organonitrogen compound catabolic process	GO:1901565	179	0.066
catechol containing compound metabolic process	GO:0009712	19	0.066
single organism biosynthetic process	GO:0044711	342	0.064
monocarboxylic acid metabolic process	GO:0032787	152	0.063
cellular catabolic process	GO:0044248	295	0.063	Rat
estrogen catabolic process	GO:0006711	1	0.062	Rat
phenylpropanoid metabolic process	GO:0009698	5	0.062	Rat
cellular modified amino acid metabolic process	GO:0006575	61	0.060
acylglycerol metabolic process	GO:0006639	21	0.060
response to transition metal nanoparticle	GO:1990267	122	0.058
response to external biotic stimulus	GO:0043207	221	0.057	Rat
response to inorganic substance	GO:0010035	377	0.057
glycerolipid metabolic process	GO:0046486	67	0.054
hormone metabolic process	GO:0042445	69	0.054	Rat
exogenous drug catabolic process	GO:0042738	1	0.053
response to bacterium	GO:0009617	200	0.053	Rat
heterocycle catabolic process	GO:0046700	167	0.051	Rat
cellular response to external stimulus	GO:0071496	118	0.050
response to acid chemical	GO:0001101	222	0.049
behavior	GO:0007610	205	0.047	Fly
cellular response to ethanol	GO:0071361	13	0.046	Rat
organic substance catabolic process	GO:1901575	316	0.046	Rat
fatty acid metabolic process	GO:0006631	99	0.045
cellular response to ketone	GO:1901655	51	0.045	Rat
programmed cell death	GO:0012501	392	0.045
response to camp	GO:0051591	91	0.044
unsaturated fatty acid metabolic process	GO:0033559	39	0.044
regulation of apoptotic process	GO:0042981	335	0.043
reproductive process	GO:0022414	372	0.042
response to vitamin	GO:0033273	131	0.042
response to purine containing compound	GO:0014074	126	0.042
secondary alcohol metabolic process	GO:1902652	2	0.041
cellular response to insulin stimulus	GO:0032869	81	0.041
terpenoid metabolic process	GO:0006721	37	0.041
drug metabolic process	GO:0017144	11	0.040
organonitrogen compound biosynthetic process	GO:1901566	167	0.039
response to oxygen levels	GO:0070482	265	0.038
response to dexamethasone	GO:0071548	49	0.038
regeneration	GO:0031099	163	0.038	Rat
response to insulin	GO:0032868	133	0.038
response to testosterone	GO:0033574	55	0.037	Rat
cellular ketone metabolic process	GO:0042180	51	0.036
fat soluble vitamin biosynthetic process	GO:0042362	2	0.036
response to insecticide	GO:0017085	21	0.036
circulatory system process	GO:0003013	183	0.036
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.035
lipid biosynthetic process	GO:0008610	128	0.035
regulation of cellular ketone metabolic process	GO:0010565	27	0.035
drug catabolic process	GO:0042737	1	0.035
blood circulation	GO:0008015	183	0.034
regulation of neuron death	GO:1901214	115	0.034
regulation of tube size	GO:0035150	89	0.033
response to estrogen	GO:0043627	232	0.033
nitrogen cycle metabolic process	GO:0071941	5	0.032
response to mercury ion	GO:0046689	15	0.032
organophosphate metabolic process	GO:0019637	370	0.032
neurological system process	GO:0050877	219	0.032	Rat Fly
fatty acid derivative metabolic process	GO:1901568	38	0.031
cellular amine metabolic process	GO:0044106	38	0.031
regulation of hormone levels	GO:0010817	187	0.031	Rat
cellular lipid metabolic process	GO:0044255	208	0.031
defense response	GO:0006952	194	0.031	Rat
regulation of anatomical structure size	GO:0090066	135	0.030
carbohydrate derivative catabolic process	GO:1901136	147	0.030
epoxygenase p450 pathway	GO:0019373	1	0.030
cellular response to extracellular stimulus	GO:0031668	73	0.029
positive regulation of biosynthetic process	GO:0009891	319	0.029
nitrogen compound transport	GO:0071705	229	0.029
pyridine containing compound metabolic process	GO:0072524	32	0.028
response to oxidative stress	GO:0006979	186	0.028
apoptotic process	GO:0006915	381	0.028
amine metabolic process	GO:0009308	38	0.028
macromolecule localization	GO:0033036	252	0.027
benzene containing compound metabolic process	GO:0042537	22	0.027	Rat
homeostatic process	GO:0042592	331	0.027
multi organism reproductive process	GO:0044703	262	0.027
multi multicellular organism process	GO:0044706	138	0.026
regulation of cell proliferation	GO:0042127	359	0.026
protein transport	GO:0015031	132	0.025
nucleobase containing small molecule metabolic process	GO:0055086	316	0.025
transmembrane transport	GO:0055085	412	0.025
alpha amino acid metabolic process	GO:1901605	71	0.025
negative regulation of metabolic process	GO:0009892	331	0.025
phenol containing compound metabolic process	GO:0018958	30	0.025
organophosphate catabolic process	GO:0046434	148	0.024
response to toxic substance	GO:0009636	133	0.024
response to estradiol	GO:0032355	164	0.024
purine ribonucleotide metabolic process	GO:0009150	227	0.024
purine nucleoside metabolic process	GO:0042278	169	0.023
cellular macromolecule localization	GO:0070727	122	0.023
nucleoside phosphate metabolic process	GO:0006753	283	0.023
oxidative demethylation	GO:0070989	2	0.023
nucleotide metabolic process	GO:0009117	279	0.023
single organism carbohydrate metabolic process	GO:0044723	118	0.022
cellular homeostasis	GO:0019725	252	0.022
response to vitamin d	GO:0033280	34	0.022
cellular nitrogen compound catabolic process	GO:0044270	163	0.022
regulation of secretion	GO:0051046	224	0.022
negative regulation of apoptotic process	GO:0043066	181	0.022
cellular alcohol biosynthetic process	GO:0044108	2	0.022
triglyceride metabolic process	GO:0006641	21	0.022
sensory perception of smell	GO:0007608	5	0.022	Rat Fly
regulation of hydrolase activity	GO:0051336	143	0.021
inflammatory response	GO:0006954	150	0.021	Rat
cellular response to stress	GO:0033554	269	0.021
regulation of blood pressure	GO:0008217	83	0.021
negative regulation of secretion	GO:0051048	82	0.021
purine ribonucleotide catabolic process	GO:0009154	136	0.020
monosaccharide metabolic process	GO:0005996	61	0.020
ribonucleoside metabolic process	GO:0009119	174	0.020
response to sulfur dioxide	GO:0010477	3	0.020
response to decreased oxygen levels	GO:0036293	237	0.020
regulation of tolerance induction dependent upon immune response	GO:0002652	1	0.020
isoprenoid metabolic process	GO:0006720	45	0.020
regulation of cellular amine metabolic process	GO:0033238	8	0.020
response to carbohydrate	GO:0009743	183	0.020
single organism reproductive process	GO:0044702	297	0.020
single organism behavior	GO:0044708	130	0.020
generation of precursor metabolites and energy	GO:0006091	62	0.019
multicellular organismal signaling	GO:0035637	44	0.019
diterpenoid metabolic process	GO:0016101	33	0.019
coumarin metabolic process	GO:0009804	5	0.019	Rat
carbohydrate derivative metabolic process	GO:1901135	346	0.019
positive regulation of transport	GO:0051050	245	0.019
catecholamine metabolic process	GO:0006584	19	0.019
regulation of tolerance induction to nonself antigen	GO:0002655	1	0.019
amide transport	GO:0042886	105	0.019
regulation of cellular amino acid metabolic process	GO:0006521	2	0.019
response to amino acid	GO:0043200	75	0.019
neutral lipid metabolic process	GO:0006638	21	0.019
organic hydroxy compound biosynthetic process	GO:1901617	51	0.019
carbohydrate derivative biosynthetic process	GO:1901137	124	0.018
artery smooth muscle contraction	GO:0014824	4	0.018
regulation of protein metabolic process	GO:0051246	289	0.018
arachidonic acid metabolic process	GO:0019369	20	0.018
regulation of phosphate metabolic process	GO:0019220	349	0.018
negative regulation of natural killer cell mediated immunity	GO:0002716	4	0.018
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.018
regulation of blood circulation	GO:1903522	110	0.017
purine ribonucleoside metabolic process	GO:0046128	168	0.017
response to alkaloid	GO:0043279	132	0.017
estrogen metabolic process	GO:0008210	11	0.017	Rat
negative regulation of cell communication	GO:0010648	158	0.017
purine containing compound metabolic process	GO:0072521	253	0.017
alcohol metabolic process	GO:0006066	77	0.017
negative regulation of cellular metabolic process	GO:0031324	281	0.017
regulation of vasculature development	GO:1901342	44	0.017
positive regulation of cell death	GO:0010942	184	0.017
positive regulation of response to stimulus	GO:0048584	285	0.017
regulation of phosphorus metabolic process	GO:0051174	349	0.016
purine nucleotide metabolic process	GO:0006163	229	0.016
intracellular transport	GO:0046907	185	0.016
response to hypoxia	GO:0001666	231	0.016
nucleoside phosphate catabolic process	GO:1901292	140	0.016
small gtpase mediated signal transduction	GO:0007264	36	0.016
response to starvation	GO:0042594	59	0.016	Rat
regulation of extracellular matrix constituent secretion	GO:0003330	2	0.016
cellular ion homeostasis	GO:0006873	184	0.016
nucleoside metabolic process	GO:0009116	179	0.016
response to calcium ion	GO:0051592	59	0.016
heart morphogenesis	GO:0003007	3	0.015
nucleobase containing compound catabolic process	GO:0034655	152	0.015
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.015
cellular response to nutrient levels	GO:0031669	60	0.015
protein localization	GO:0008104	191	0.015
ras protein signal transduction	GO:0007265	29	0.015
sensory perception	GO:0007600	101	0.015	Rat Fly
c21 steroid hormone metabolic process	GO:0008207	14	0.015
protein oligomerization	GO:0051259	191	0.015
ion homeostasis	GO:0050801	212	0.015
macromolecular complex assembly	GO:0065003	273	0.015
carbohydrate catabolic process	GO:0016052	40	0.015
regulation of response to external stimulus	GO:0032101	106	0.015
dopamine metabolic process	GO:0042417	12	0.015
negative regulation of cell death	GO:0060548	229	0.015
ribonucleotide catabolic process	GO:0009261	136	0.015
negative regulation of transport	GO:0051051	136	0.015
cell cycle checkpoint	GO:0000075	2	0.014
negative regulation of secretion by cell	GO:1903531	72	0.014
protein homooligomerization	GO:0051260	91	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.014
peptidyl amino acid modification	GO:0018193	126	0.014
glycosyl compound metabolic process	GO:1901657	182	0.014
immune response	GO:0006955	104	0.014
acute inflammatory response	GO:0002526	58	0.014	Rat
response to cadmium ion	GO:0046686	35	0.014
positive regulation of cellular amine metabolic process	GO:0033240	3	0.014
ribonucleoside catabolic process	GO:0042454	126	0.014
purine nucleotide catabolic process	GO:0006195	136	0.014
positive regulation of purine nucleotide metabolic process	GO:1900544	91	0.014
multicellular organismal reproductive process	GO:0048609	233	0.014
multicellular organism growth	GO:0035264	1	0.014
regulation of lipid metabolic process	GO:0019216	68	0.014
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.014
ribonucleotide metabolic process	GO:0009259	231	0.014
negative regulation of serine type endopeptidase activity	GO:1900004	1	0.014
secretion	GO:0046903	307	0.014
transmission of nerve impulse	GO:0019226	42	0.014
response to radiation	GO:0009314	137	0.014
positive regulation of blood circulation	GO:1903524	65	0.014
cellular carbohydrate metabolic process	GO:0044262	72	0.013
purine nucleoside catabolic process	GO:0006152	124	0.013
regulation of cell development	GO:0060284	263	0.013
positive regulation of catalytic activity	GO:0043085	184	0.013
regulation of catalytic activity	GO:0050790	304	0.013
acute phase response	GO:0006953	20	0.013	Rat
long chain fatty acid metabolic process	GO:0001676	32	0.013
positive regulation of nucleotide biosynthetic process	GO:0030810	36	0.013
vascular process in circulatory system	GO:0003018	96	0.013
chemical homeostasis	GO:0048878	292	0.013
phenol containing compound biosynthetic process	GO:0046189	9	0.013
intracellular signal transduction	GO:0035556	314	0.013
cellular response to vitamin d	GO:0071305	12	0.013
single organism intracellular transport	GO:1902582	166	0.012
vasoconstriction	GO:0042310	54	0.012
cardiac chamber development	GO:0003205	1	0.012
vitamin d3 metabolic process	GO:0070640	2	0.012
regulation of blood vessel size	GO:0050880	89	0.012
response to reactive oxygen species	GO:0000302	120	0.012
purine containing compound catabolic process	GO:0072523	138	0.012
positive regulation of phosphate metabolic process	GO:0045937	262	0.012
glycosyl compound catabolic process	GO:1901658	126	0.012
lipid storage	GO:0019915	1	0.012
energy derivation by oxidation of organic compounds	GO:0015980	46	0.012
response to growth factor	GO:0070848	189	0.012
sequestering of metal ion	GO:0051238	9	0.012
membrane organization	GO:0061024	94	0.012
regulation of cellular localization	GO:0060341	263	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.012
vitamin d metabolic process	GO:0042359	4	0.012
lauric acid metabolic process	GO:0048252	4	0.012
positive regulation of cellular biosynthetic process	GO:0031328	295	0.012
cellular response to vitamin	GO:0071295	21	0.012
negative regulation of natural killer cell mediated cytotoxicity	GO:0045953	4	0.012
reactive oxygen species biosynthetic process	GO:1903409	8	0.012
cellular amide metabolic process	GO:0043603	44	0.012
carbohydrate metabolic process	GO:0005975	130	0.012
gamete generation	GO:0007276	124	0.012
response to temperature stimulus	GO:0009266	94	0.012
maintenance of location	GO:0051235	17	0.012
epithelial cell differentiation	GO:0030855	71	0.012
nucleotide biosynthetic process	GO:0009165	98	0.011
establishment of protein localization	GO:0045184	141	0.011
cellular response to mechanical stimulus	GO:0071260	48	0.011
positive regulation of cell development	GO:0010720	176	0.011
tonic smooth muscle contraction	GO:0014820	4	0.011
toxin catabolic process	GO:0009407	1	0.011
nucleoside monophosphate metabolic process	GO:0009123	93	0.011
vitamin d biosynthetic process	GO:0042368	2	0.011
single organism cellular localization	GO:1902580	102	0.011
protein complex assembly	GO:0006461	263	0.011
glucose homeostasis	GO:0042593	75	0.011
cytoplasmic transport	GO:0016482	115	0.011
regulation of catecholamine secretion	GO:0050433	32	0.011
camp metabolic process	GO:0046058	63	0.011
platelet aggregation	GO:0070527	4	0.011
macromolecular complex subunit organization	GO:0043933	339	0.011
catecholamine biosynthetic process	GO:0042423	9	0.011
response to zinc ion	GO:0010043	39	0.011
nucleoside triphosphate catabolic process	GO:0009143	123	0.011
insulin like growth factor receptor signaling pathway	GO:0048009	3	0.011
regulation of cell differentiation	GO:0045595	320	0.011
innate immune response	GO:0045087	35	0.011
cellular protein localization	GO:0034613	122	0.011
positive regulation of protein metabolic process	GO:0051247	178	0.011
divalent inorganic cation homeostasis	GO:0072507	165	0.011
vitamin biosynthetic process	GO:0009110	3	0.011
brain development	GO:0007420	247	0.011
coenzyme metabolic process	GO:0006732	86	0.011
ribose phosphate biosynthetic process	GO:0046390	87	0.011
vasodilation	GO:0042311	44	0.011
negative regulation of neuron death	GO:1901215	69	0.011
growth	GO:0040007	165	0.011
nucleoside triphosphate metabolic process	GO:0009141	144	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.011
cellular response to nutrient	GO:0031670	30	0.010
regulation of vasodilation	GO:0042312	36	0.010
steroid biosynthetic process	GO:0006694	48	0.010
nucleotide catabolic process	GO:0009166	139	0.010
regulation of insulin secretion	GO:0050796	65	0.010
muscle system process	GO:0003012	115	0.010
hexose metabolic process	GO:0019318	58	0.010
regulation of peptide transport	GO:0090087	87	0.010
neuromuscular process	GO:0050905	2	0.010
protein complex biogenesis	GO:0070271	263	0.010
cellular chemical homeostasis	GO:0055082	247	0.010
purine nucleoside monophosphate metabolic process	GO:0009126	84	0.010
regulation of catabolic process	GO:0009894	113	0.010
negative regulation of response to stimulus	GO:0048585	155	0.010
ribose phosphate metabolic process	GO:0019693	235	0.010
response to ionizing radiation	GO:0010212	59	0.010

Ugt2b37 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
cardiovascular system disease	DOID:1287	0.035
disease of anatomical entity	DOID:7	0.035
inherited metabolic disorder	DOID:655	0.022
disease of metabolism	DOID:0014667	0.022
nervous system disease	DOID:863	0.014
vascular disease	DOID:178	0.011
artery disease	DOID:0050828	0.011
central nervous system disease	DOID:331	0.011

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