Rattus norvegicus

375 known processes

Ager

advanced glycosylation end product-specific receptor

(Aliases: RAGE)

Ager biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transcription from rna polymerase ii promoterGO:00063662520.558
transcription dna templatedGO:00063513770.359
Human
tissue developmentGO:00098882520.293
biological adhesionGO:00226101100.288
rna metabolic processGO:00160704060.285
Human
central nervous system developmentGO:00074173110.282
brain developmentGO:00074202470.268
regulation of rna metabolic processGO:00512523910.263
Human
negative regulation of cell differentiationGO:0045596990.243
regulation of nucleic acid templated transcriptionGO:19035063800.239
Human
regulation of cell differentiationGO:00455953200.238
regulation of neuron differentiationGO:00456642080.229
rna biosynthetic processGO:00327743800.225
Human
cell projection organizationGO:00300303020.199
regulation of ion transportGO:00432692450.177
positive regulation of multicellular organismal processGO:00512403870.165
response to extracellular stimulusGO:00099913800.165
nucleic acid templated transcriptionGO:00976593790.164
Human
response to nutrient levelsGO:00316673700.161
negative regulation of cell developmentGO:0010721820.159
cation transportGO:00068123820.158
positive regulation of biosynthetic processGO:00098913190.154
epithelium developmentGO:0060429960.154
apoptotic processGO:00069153810.149
positive regulation of rna metabolic processGO:00512542030.144
ion transmembrane transportGO:00342203650.134
regulation of rna biosynthetic processGO:20011413810.132
Human
positive regulation of transcription dna templatedGO:00458931970.129
positive regulation of rna biosynthetic processGO:19026801970.128
negative regulation of neurogenesisGO:0050768780.127
response to oxygen levelsGO:00704822650.126
neuron differentiationGO:00301823680.124
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.121
regulation of neurogenesisGO:00507672470.119
head developmentGO:00603222470.118
nitrogen compound transportGO:00717052290.118
cardiac ventricle developmentGO:000323110.116
negative regulation of transcription dna templatedGO:00458921160.113
positive regulation of cellular biosynthetic processGO:00313282950.112
organ morphogenesisGO:0009887750.111
regulation of nervous system developmentGO:00519602640.105
neuron projection developmentGO:00311752730.099
positive regulation of nitrogen compound metabolic processGO:00511733340.098
inorganic cation transmembrane transportGO:00986622020.098
negative regulation of developmental processGO:00510931250.094
negative regulation of neuron differentiationGO:0045665620.093
regulation of molecular functionGO:00650093980.093
cation transmembrane transportGO:00986552630.090
neuron apoptotic processGO:0051402880.090
homeostatic processGO:00425923310.089
cellular chemical homeostasisGO:00550822470.088
negative regulation of nucleobase containing compound metabolic processGO:00459341530.088
negative regulation of nervous system developmentGO:0051961790.088
neuron developmentGO:00486662860.087
negative regulation of nucleic acid templated transcriptionGO:19035071170.087
positive regulation of nucleic acid templated transcriptionGO:19035081970.084
cell morphogenesisGO:00009021420.083
transmembrane transportGO:00550854120.080
multicellular organism reproductionGO:00325042330.079
single organism reproductive processGO:00447022970.079
cellular component biogenesisGO:00440853680.078
regulation of cell developmentGO:00602842630.076
protein oligomerizationGO:00512591910.076
heart morphogenesisGO:000300730.075
cellular response to endogenous stimulusGO:00714953770.072
response to carbohydrateGO:00097431830.069
regulation of transcription dna templatedGO:00063553740.069
Human
positive regulation of molecular functionGO:00440932300.067
macromolecular complex assemblyGO:00650032730.065
regulation of transcription from rna polymerase ii promoterGO:00063572340.065
positive regulation of gene expressionGO:00106282440.065
cellular component assemblyGO:00226073600.065
positive regulation of developmental processGO:00510942830.063
defecationGO:003042110.059
s shaped body morphogenesisGO:007205020.057
response to acid chemicalGO:00011012220.057
cellular response to oxygen containing compoundGO:19017013860.057
negative regulation of nitrogen compound metabolic processGO:00511721610.056
positive regulation of nucleotide biosynthetic processGO:0030810360.056
programmed cell deathGO:00125013920.055
negative regulation of metabolic processGO:00098923310.055
negative regulation of cellular metabolic processGO:00313242810.055
positive regulation of phosphorus metabolic processGO:00105622620.055
negative regulation of macromolecule biosynthetic processGO:00105581480.053
positive regulation of nucleobase containing compound metabolic processGO:00459353190.053
regulation of phosphate metabolic processGO:00192203490.052
regulation of multicellular organismal developmentGO:20000263760.052
protein complex biogenesisGO:00702712630.052
response to inorganic substanceGO:00100353770.051
carbohydrate derivative metabolic processGO:19011353460.050
negative regulation of rna biosynthetic processGO:19026791180.050
regulation of cell projection organizationGO:00313441750.050
response to glucoseGO:00097491360.050
positive regulation of serotonin secretionGO:001406410.049
response to hexoseGO:00097461440.049
negative regulation of cell communicationGO:00106481580.049
enzyme linked receptor protein signaling pathwayGO:00071671160.049
response to nutrientGO:00075842480.048
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.048
negative regulation of cellular biosynthetic processGO:00313271610.047
anterior posterior pattern specificationGO:000995210.047
regulation of secretionGO:00510462240.046
positive regulation of apoptotic processGO:00430651540.046
purine nucleotide metabolic processGO:00061632290.046
glucose homeostasisGO:0042593750.045
regulation of respiratory gaseous exchange by neurological system processGO:000208710.044
negative regulation of biosynthetic processGO:00098901680.044
catabolic processGO:00090563510.044
mesoderm developmentGO:000749820.044
regulation of cell proliferationGO:00421273590.043
metanephric comma shaped body morphogenesisGO:007227820.043
positive regulation of macromolecule biosynthetic processGO:00105572470.043
comma shaped body morphogenesisGO:007204920.042
regulation of cell morphogenesisGO:0022604770.042
motor neuron axon guidanceGO:000804510.042
protein complex assemblyGO:00064612630.042
response to decreased oxygen levelsGO:00362932370.041
Mouse
cell projection morphogenesisGO:00488581230.041
single organism behaviorGO:00447081300.041
cellular amide metabolic processGO:0043603440.041
secretionGO:00469033070.041
regulation of neuron projection developmentGO:00109751610.040
organic substance catabolic processGO:19015753160.040
immune system processGO:00023762040.040
reproductionGO:00000032450.039
response to growth factorGO:00708481890.039
cellular response to abiotic stimulusGO:0071214850.039
metanephric s shaped body morphogenesisGO:007228420.039
response to external biotic stimulusGO:00432072210.039
locomotory exploration behaviorGO:003564110.038
protein complex subunit organizationGO:00718223020.038
type b pancreatic cell proliferationGO:004434230.038
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.038
response to biotic stimulusGO:00096072260.037
chemical homeostasisGO:00488782920.037
negative regulation of multicellular organismal processGO:00512412030.037
synaptic growth at neuromuscular junctionGO:005112410.037
positive regulation of signalingGO:00230562700.036
Mouse
regulation of apoptotic processGO:00429813350.035
tube developmentGO:0035295890.035
muscle structure developmentGO:0061061870.035
reproductive system developmentGO:00614581280.035
excretionGO:0007588240.035
multi organism reproductive processGO:00447032620.035
ribonucleotide biosynthetic processGO:0009260850.034
regulation of cytokine productionGO:0001817560.034
cell cell signalingGO:00072673350.034
protein homooligomerizationGO:0051260910.034
negative regulation of gene expressionGO:00106291990.033
ion homeostasisGO:00508012120.033
positive regulation of neurogenesisGO:00507691650.033
negative regulation of macromolecule metabolic processGO:00106052600.033
regulation of synaptic transmissionGO:00508041410.033
response to estrogenGO:00436272320.033
cardiovascular system developmentGO:00723581340.033
regulation of cellular amine metabolic processGO:003323880.032
ribonucleotide metabolic processGO:00092592310.031
purine nucleotide biosynthetic processGO:0006164830.031
circulatory system developmentGO:00723591340.031
nucleoside phosphate biosynthetic processGO:19012931020.031
purine ribonucleotide metabolic processGO:00091502270.030
secretion by cellGO:00329402480.030
anatomical structure morphogenesisGO:00096532980.030
positive regulation of neuron differentiationGO:00456661260.030
negative regulation of rna metabolic processGO:00512531230.030
inorganic ion transmembrane transportGO:00986602290.030
cell part morphogenesisGO:00329901230.030
reproductive processGO:00224143720.030
neurological system processGO:00508772190.029
response to hypoxiaGO:00016662310.029
Mouse
developmental growthGO:00485891000.029
regulation of cell cycleGO:0051726730.029
positive regulation of cell developmentGO:00107201760.028
cell morphogenesis involved in differentiationGO:00009041190.028
retinal ganglion cell axon guidanceGO:003129010.028
response to corticosteroidGO:00319602350.028
response to other organismGO:00517072200.028
positive regulation of purine nucleotide biosynthetic processGO:1900373360.028
gastrulationGO:000736920.028
skeletal system developmentGO:0001501410.028
negative regulation of cell deathGO:00605482290.027
regulation of immune system processGO:00026821230.027
learning or memoryGO:0007611900.027
circulatory system processGO:00030131830.027
sensory perceptionGO:00076001010.027
response to cytokineGO:00340972150.027
carbohydrate homeostasisGO:0033500750.027
digestive system developmentGO:0055123410.027
nerve developmentGO:0021675110.026
monoamine transportGO:0015844430.026
divalent inorganic cation homeostasisGO:00725071650.026
organic hydroxy compound transportGO:0015850770.026
positive regulation of cell deathGO:00109421840.026
multicellular organismal reproductive processGO:00486092330.026
embryo developmentGO:0009790490.025
macromolecular complex subunit organizationGO:00439333390.025
behaviorGO:00076102050.024
Mouse
positive regulation of programmed cell deathGO:00430681570.024
sexual reproductionGO:00199531480.024
regulation of cellular component organizationGO:00511283680.024
single organism organelle organizationGO:19025891800.024
locomotionGO:00400112370.024
regulation of programmed cell deathGO:00430673410.024
protein localizationGO:00081041910.024
Mouse
skeletal muscle cell differentiationGO:003591420.024
adult locomotory behaviorGO:000834440.024
positive regulation of nucleotide metabolic processGO:0045981910.023
palate developmentGO:006002120.023
cyclic purine nucleotide metabolic processGO:0052652620.023
positive regulation of phosphate metabolic processGO:00459372620.023
cellular catabolic processGO:00442482950.023
organelle organizationGO:00069962660.023
forebrain developmentGO:0030900980.023
response to metal ionGO:00100382530.023
regulation of transferase activityGO:00513381230.023
Mouse
sensory perception of painGO:0019233730.022
cellular homeostasisGO:00197252520.022
organonitrogen compound catabolic processGO:19015651790.022
positive regulation of response to stimulusGO:00485842850.022
single organism biosynthetic processGO:00447113420.022
negative regulation of calcium ion importGO:009028120.022
cyclic nucleotide metabolic processGO:0009187800.021
proteolysisGO:00065081750.021
morphogenesis of an epitheliumGO:0002009200.021
nucleoside phosphate metabolic processGO:00067532830.021
negative regulation of cellular component organizationGO:0051129830.021
cellular response to lipidGO:00713962010.021
regulation of ion transmembrane transportGO:00347651210.021
regulation of catecholamine secretionGO:0050433320.021
regulation of defecationGO:200029210.020
regulation of cellular ketone metabolic processGO:0010565270.020
metal ion transportGO:00300012890.020
positive regulation of cell differentiationGO:00455972170.020
nucleobase containing small molecule metabolic processGO:00550863160.020
purine containing compound metabolic processGO:00725212530.020
carboxylic acid transportGO:00469421150.020
negative regulation of signal transductionGO:0009968830.020
regulation of cellular amino acid metabolic processGO:000652120.020
regulation of phosphorus metabolic processGO:00511743490.020
neuron projection morphogenesisGO:00488121220.020
gonadotropin secretionGO:003227480.019
regulation of follicle stimulating hormone secretionGO:004688050.019
gamete generationGO:00072761240.019
organophosphate metabolic processGO:00196373700.019
organic acid transportGO:00158491160.019
multicellular organismal water homeostasisGO:005089140.019
heart developmentGO:0007507720.019
noradrenergic neuron differentiationGO:000335710.019
negative regulation of signalingGO:00230571570.019
formation of primary germ layerGO:000170410.019
regulation of axonogenesisGO:0050770370.019
muscle tissue morphogenesisGO:006041510.018
synaptic transmissionGO:00072682350.018
gliogenesisGO:0042063930.018
response to transition metal nanoparticleGO:19902671220.018
cellular cation homeostasisGO:00300031800.018
calcium ion transportGO:00068161310.018
regulation of secretion by cellGO:19035302080.018
cell morphogenesis involved in neuron differentiationGO:00486671060.018
negative regulation of molecular functionGO:00440921330.018
dna metabolic processGO:0006259960.018
response to peptide hormoneGO:00434342780.018
chemosensory behaviorGO:000763520.018
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:003114510.018
b cell differentiationGO:003018320.018
positive regulation of ion transportGO:0043270940.017
regulation of cellular localizationGO:00603412630.017
response to fluorideGO:190261730.017
regulation of signal transductionGO:00099663180.017
Mouse
calcium ion homeostasisGO:00550741620.017
learningGO:0007612330.017
renal system developmentGO:0072001670.017
peptide biosynthetic processGO:004304330.017
muscle tissue developmentGO:0060537580.017
positive regulation of nervous system developmentGO:00519621780.017
localization of cellGO:00516742020.017
bmp signaling pathwayGO:003050940.017
dendrite developmentGO:0016358720.017
positive regulation of amine transportGO:0051954260.017
cellular response to acid chemicalGO:0071229750.017
response to axon injuryGO:0048678590.016
axon developmentGO:0061564960.016
metanephric part of ureteric bud developmentGO:003550210.016
amide transportGO:00428861050.016
positive regulation of cell projection organizationGO:00313461110.016
negative regulation of transportGO:00510511360.016
negative regulation of intracellular estrogen receptor signaling pathwayGO:003314720.016
mesoderm formationGO:000170710.016
muscle organ developmentGO:0007517500.016
carboxylic acid metabolic processGO:00197522890.016
negative regulation of growthGO:0045926370.016
regulation of growthGO:00400081050.016
negative regulation of cell projection organizationGO:0031345500.016
intracellular transportGO:00469071850.016
ribonucleoside triphosphate metabolic processGO:00091991410.016
regulation of purine nucleotide metabolic processGO:19005421150.016
negative regulation of follicle stimulating hormone secretionGO:004688230.016
growthGO:00400071650.016
axis specificationGO:000979840.016
regulation of cellular protein metabolic processGO:00322682670.015
purine nucleoside catabolic processGO:00061521240.015
regulation of system processGO:00440572080.015
agingGO:00075682410.015
olfactory behaviorGO:004204820.015
regulation of proteasomal protein catabolic processGO:006113640.015
protein heterooligomerizationGO:0051291890.015
response to glucocorticoidGO:00513842230.015
positive regulation of secretionGO:00510471400.015
nucleotide biosynthetic processGO:0009165980.015
organonitrogen compound biosynthetic processGO:19015661670.015
muscle system processGO:00030121150.014
gonad developmentGO:00084061040.014
positive regulation of cellular amine metabolic processGO:003324030.014
peptide metabolic processGO:0006518320.014
positive regulation of purine nucleotide metabolic processGO:1900544910.014
transmission of nerve impulseGO:0019226420.014
negative regulation of neuron projection developmentGO:0010977460.014
cell fate determinationGO:000170920.014
protein autophosphorylationGO:0046777660.014
regulation of anatomical structure morphogenesisGO:00226031410.014
cell cycleGO:00070491010.014
positive regulation of cell proliferationGO:00082842490.014
regulation of metanephros developmentGO:007221540.014
neuron fate commitmentGO:004866340.014
multi multicellular organism processGO:00447061380.014
endochondral bone growthGO:000341630.014
defense responseGO:00069521940.014
regulation of insulin secretionGO:0050796650.014
cardiac chamber developmentGO:000320510.014
antigen processing and presentationGO:001988220.014
action potentialGO:0001508540.014
visual perceptionGO:000760130.014
apoptotic signaling pathwayGO:0097190270.014
regulation of muscle tissue developmentGO:1901861250.014
norepinephrine secretionGO:0048243160.013
regulation of blood circulationGO:19035221100.013
maintenance of locationGO:0051235170.013
response to estradiolGO:00323551640.013
cellular ketone metabolic processGO:0042180510.013
response to lipopolysaccharideGO:00324961910.013
mitotic sister chromatid separationGO:005130610.013
response to purine containing compoundGO:00140741260.013
regulation of phosphorylationGO:00423252480.013
oxoacid metabolic processGO:00434362900.013
chromosome segregationGO:000705920.013
cellular component morphogenesisGO:00329891550.013
digestive tract developmentGO:0048565390.013
spindle organizationGO:000705120.013
regulation of cell morphogenesis involved in differentiationGO:0010769720.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.013
organ formationGO:004864530.013
blood circulationGO:00080151830.013
thigmotaxisGO:000196610.013
regulation of neuronal synaptic plasticityGO:0048168310.013
embryonic skeletal system developmentGO:004870630.013
sex differentiationGO:00075481130.013
dendrite morphogenesisGO:0048813430.013
positive regulation of cellular component organizationGO:00511302000.013
cardiac muscle tissue morphogenesisGO:005500810.012
skeletal system morphogenesisGO:0048705120.012
negative regulation of canonical wnt signaling pathwayGO:009009040.012
positive regulation of peptide secretionGO:0002793520.012
negative regulation of defecationGO:200029310.012
embryonic morphogenesisGO:0048598140.012
purine containing compound biosynthetic processGO:0072522850.012
ras protein signal transductionGO:0007265290.012
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.012
male mating behaviorGO:006017930.012
cognitionGO:0050890920.012
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.012
regulation of interleukin 6 productionGO:0032675120.012
signal releaseGO:00230611450.012
chromosome organizationGO:0051276360.012
cell projection assemblyGO:0030031210.012
development of primary sexual characteristicsGO:00451371070.012
mesoderm morphogenesisGO:004833210.012
organophosphate biosynthetic processGO:00904071430.012
behavioral response to ethanolGO:004814910.012
embryonic pattern specificationGO:000988010.011
reproductive structure developmentGO:00486081280.011
desensitization of g protein coupled receptor protein signaling pathwayGO:0002029100.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
nucleotide metabolic processGO:00091172790.011
regulation of catabolic processGO:00098941130.011
purine ribonucleoside metabolic processGO:00461281680.011
nucleoside triphosphate metabolic processGO:00091411440.011
regenerationGO:00310991630.011
cellular response to stressGO:00335542690.011
insulin secretionGO:0030073690.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
diencephalon developmentGO:0021536210.011
regulation of blood pressureGO:0008217830.011
mapk cascadeGO:00001651400.011
Mouse
cytosolic calcium ion homeostasisGO:00514801400.011
regulation of peptide secretionGO:0002791820.011
regulation of respiratory gaseous exchangeGO:004357620.011
carbohydrate derivative biosynthetic processGO:19011371240.011
embryonic axis specificationGO:000057810.011
regulation of apoptotic signaling pathwayGO:2001233130.011
negative regulation of metanephros developmentGO:007221720.011
tissue morphogenesisGO:0048729220.011
muscle organ morphogenesisGO:004864410.011
cell type specific apoptotic processGO:00972851340.011
protein tetramerizationGO:0051262380.011
ribose phosphate metabolic processGO:00196932350.011
negative regulation of developmental growthGO:0048640150.011
embryonic skeletal system morphogenesisGO:004870430.010
hypothalamus developmentGO:0021854110.010
protein phosphorylationGO:00064683450.010
positive regulation of cytokine productionGO:0001819420.010
metaphase anaphase transition of mitotic cell cycleGO:000709110.010
cell adhesionGO:00071551100.010
monovalent inorganic cation transportGO:00156721720.010
male gamete generationGO:0048232990.010
cell differentiation involved in kidney developmentGO:006100540.010
tube morphogenesisGO:0035239230.010
cytokine productionGO:0001816610.010
regulation of kinase activityGO:00435491170.010
Mouse
organic acid metabolic processGO:00060822920.010
negative regulation of insulin receptor signaling pathwayGO:0046627100.010
immune responseGO:00069551040.010
cellular ion homeostasisGO:00068731840.010

Ager disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
lower respiratory tract diseaseDOID:005016100.024
disease of anatomical entityDOID:700.024
respiratory system diseaseDOID:157900.024
primary ciliary dyskinesiaDOID:956200.018
kidney diseaseDOID:55700.016
urinary system diseaseDOID:1800.016
sensory system diseaseDOID:005015500.015
nervous system diseaseDOID:86300.015