Rattus norvegicus

7 known processes

B2m

beta-2 microglobulin

B2m biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of tolerance induction dependent upon immune responseGO:000265210.629
positive regulation of tolerance inductionGO:000264510.480
wound healingGO:00420601220.455
regulation of tolerance induction to nonself antigenGO:000265510.398
female pregnancyGO:00075651220.395
t cell tolerance inductionGO:000251730.354
cellular catabolic processGO:00442482950.269
regulation of phosphorus metabolic processGO:00511743490.224
response to estradiolGO:00323551640.217
reproductive processGO:00224143720.206
negative regulation of cell deathGO:00605482290.206
tissue developmentGO:00098882520.202
organic substance catabolic processGO:19015753160.197
innate immune responseGO:0045087350.189
carboxylic acid metabolic processGO:00197522890.188
cellular amino acid metabolic processGO:00065201070.184
peptide metabolic processGO:0006518320.181
positive regulation of tolerance induction dependent upon immune responseGO:000265410.171
multi organism reproductive processGO:00447032620.166
hemostasisGO:0007599260.151
cell killingGO:0001906130.140
Mouse
regulation of blood coagulationGO:003019390.135
catabolic processGO:00090563510.134
cellular response to stressGO:00335542690.126
positive regulation of cell proliferationGO:00082842490.126
regulation of apoptotic processGO:00429813350.123
blood coagulationGO:0007596260.122
regulation of protein metabolic processGO:00512462890.122
regulation of body fluid levelsGO:0050878900.121
signal transduction by phosphorylationGO:00230141440.115
proteolysisGO:00065081750.110
mapk cascadeGO:00001651400.110
negative regulation of natural killer cell mediated immunityGO:000271640.110
organic acid metabolic processGO:00060822920.109
cellular response to iron ion starvationGO:001010610.109
programmed cell deathGO:00125013920.105
macromolecule catabolic processGO:0009057580.104
oxoacid metabolic processGO:00434362900.097
regulation of cell proliferationGO:00421273590.096
agingGO:00075682410.094
lipid biosynthetic processGO:00086101280.092
single organism catabolic processGO:00447122830.090
regulation of phosphate metabolic processGO:00192203490.087
regulation of cellular amino acid metabolic processGO:000652120.086
regulation of anatomical structure morphogenesisGO:00226031410.085
cellular amide metabolic processGO:0043603440.084
response to peptideGO:19016522920.083
negative regulation of response to stimulusGO:00485851550.080
cellular ketone metabolic processGO:0042180510.078
single organism reproductive processGO:00447022970.078
response to glucocorticoidGO:00513842230.077
positive regulation of developmental processGO:00510942830.077
response to estrogenGO:00436272320.076
negative regulation of metabolic processGO:00098923310.075
regulation of cellular ketone metabolic processGO:0010565270.073
response to inorganic substanceGO:00100353770.069
multicellular organism reproductionGO:00325042330.068
positive regulation of response to stimulusGO:00485842850.066
Mouse
regulation of cellular amine metabolic processGO:003323880.065
synaptic transmissionGO:00072682350.062
protein localizationGO:00081041910.061
nucleoside metabolic processGO:00091161790.060
protein complex biogenesisGO:00702712630.058
glycosyl compound metabolic processGO:19016571820.058
single organism biosynthetic processGO:00447113420.058
negative regulation of response to external stimulusGO:0032102370.058
regulation of vasculature developmentGO:1901342440.058
response to nutrient levelsGO:00316673700.057
organ regenerationGO:00311001010.055
negative regulation of rna metabolic processGO:00512531230.055
multicellular organismal reproductive processGO:00486092330.054
atp metabolic processGO:0046034720.052
positive regulation of multicellular organismal processGO:00512403870.052
circulatory system developmentGO:00723591340.051
nucleotide metabolic processGO:00091172790.050
protein maturationGO:0051604680.050
positive regulation of mapk cascadeGO:0043410920.050
protein phosphorylationGO:00064683450.049
protein complex assemblyGO:00064612630.048
carbohydrate derivative metabolic processGO:19011353460.048
defense responseGO:00069521940.047
positive regulation of signalingGO:00230562700.047
organic cyclic compound catabolic processGO:19013611750.047
epithelium developmentGO:0060429960.047
cellular response to oxidative stressGO:0034599760.047
intracellular signal transductionGO:00355563140.047
amine metabolic processGO:0009308380.047
regulation of signal transductionGO:00099663180.045
coagulationGO:0050817280.045
regulation of locomotionGO:00400121480.045
striated muscle tissue developmentGO:0014706580.044
response to amineGO:0014075460.044
positive regulation of phosphate metabolic processGO:00459372620.043
negative regulation of cell killingGO:003134250.043
positive regulation of tolerance induction to nonself antigenGO:000265710.042
organonitrogen compound catabolic processGO:19015651790.042
respiratory system developmentGO:0060541450.042
response to glucoseGO:00097491360.041
homeostatic processGO:00425923310.041
Human Mouse
regulation of tolerance inductionGO:000264320.041
response to monosaccharideGO:00342841590.041
regulation of transcription dna templatedGO:00063553740.040
regulation of catalytic activityGO:00507903040.040
muscle structure developmentGO:0061061870.039
regulation of molecular functionGO:00650093980.039
cellular component movementGO:00069282480.039
chemical homeostasisGO:00488782920.039
Mouse
positive regulation of phosphorus metabolic processGO:00105622620.038
response to hexoseGO:00097461440.038
cellular response to organic cyclic compoundGO:00714072020.038
positive regulation of nitrogen compound metabolic processGO:00511733340.037
response to carbohydrateGO:00097431830.037
cellular response to oxygen containing compoundGO:19017013860.037
response to starvationGO:0042594590.036
purine ribonucleotide metabolic processGO:00091502270.036
response to acid chemicalGO:00011012220.036
positive regulation of cell communicationGO:00106472710.036
ribonucleotide metabolic processGO:00092592310.036
secretionGO:00469033070.035
response to cytokineGO:00340972150.035
regulation of cell differentiationGO:00455953200.035
cellular response to endogenous stimulusGO:00714953770.035
sexual reproductionGO:00199531480.035
anatomical structure morphogenesisGO:00096532980.035
regulation of programmed cell deathGO:00430673410.034
regulation of intracellular signal transductionGO:19025312180.033
positive regulation of catalytic activityGO:00430851840.033
negative regulation of apoptotic processGO:00430661810.033
regulation of phosphorylationGO:00423252480.033
morphogenesis of an epitheliumGO:0002009200.032
reproductive structure developmentGO:00486081280.032
regulation of cellular protein metabolic processGO:00322682670.032
negative regulation of rna biosynthetic processGO:19026791180.032
response to retinoic acidGO:0032526630.032
reproductionGO:00000032450.032
response to growth factorGO:00708481890.032
nucleoside triphosphate metabolic processGO:00091411440.031
muscle tissue developmentGO:0060537580.030
organophosphate biosynthetic processGO:00904071430.030
nucleobase containing small molecule metabolic processGO:00550863160.030
cellular protein catabolic processGO:0044257190.029
carbohydrate derivative catabolic processGO:19011361470.029
negative regulation of nitrogen compound metabolic processGO:00511721610.029
regulation of cellular component movementGO:00512701500.029
positive regulation of cell deathGO:00109421840.029
cellular response to external stimulusGO:00714961180.028
positive regulation of cellular amine metabolic processGO:003324030.028
response to metal ionGO:00100382530.028
positive regulation of cellular component organizationGO:00511302000.028
multi multicellular organism processGO:00447061380.028
small molecule biosynthetic processGO:00442831240.028
prostanoid metabolic processGO:0006692120.028
cellular response to growth factor stimulusGO:00713631620.028
purine nucleoside metabolic processGO:00422781690.027
response to corticosteroidGO:00319602350.027
regulation of protein modification processGO:00313991940.027
positive regulation of cell differentiationGO:00455972170.026
tissue morphogenesisGO:0048729220.026
regulation of cellular component organizationGO:00511283680.026
carboxylic acid biosynthetic processGO:0046394830.026
prostaglandin metabolic processGO:0006693120.026
response to bacteriumGO:00096172000.026
Mouse
fatty acid derivative metabolic processGO:1901568380.026
cellular nitrogen compound catabolic processGO:00442701630.025
aromatic compound catabolic processGO:00194391680.025
macromolecule localizationGO:00330362520.024
negative regulation of multicellular organismal processGO:00512412030.024
brain developmentGO:00074202470.024
response to extracellular stimulusGO:00099913800.024
negative regulation of programmed cell deathGO:00430691830.024
response to peptide hormoneGO:00434342780.024
regulation of multicellular organismal developmentGO:20000263760.024
cellular response to hormone stimulusGO:00328702470.024
protein oligomerizationGO:00512591910.023
metanephros developmentGO:0001656140.023
positive regulation of nucleobase containing compound metabolic processGO:00459353190.023
spermatogenesisGO:0007283990.023
lymphocyte mediated immunityGO:0002449140.023
Mouse
male sex differentiationGO:0046661640.022
prostaglandin biosynthetic processGO:0001516120.022
macromolecular complex assemblyGO:00650032730.022
organophosphate metabolic processGO:00196373700.022
gland developmentGO:00487321550.022
negative regulation of cell proliferationGO:00082851190.021
positive regulation of cell developmentGO:00107201760.021
collagen metabolic processGO:0032963210.021
nucleoside catabolic processGO:00091641260.021
regulation of response to stressGO:00801341260.021
single organism intracellular transportGO:19025821660.021
apoptotic processGO:00069153810.021
activation of cysteine type endopeptidase activityGO:009720240.021
glycosyl compound catabolic processGO:19016581260.020
regulation of viral entry into host cellGO:004659630.020
positive regulation of transportGO:00510502450.020
negative regulation of immune system processGO:0002683390.020
vascular endothelial growth factor signaling pathwayGO:003808440.020
negative regulation of leukocyte apoptotic processGO:200010740.020
establishment of protein localizationGO:00451841410.020
epithelial cell differentiationGO:0030855710.020
immune responseGO:00069551040.019
Mouse
regulation of ion transportGO:00432692450.019
nucleoside phosphate metabolic processGO:00067532830.019
maternal process involved in female pregnancyGO:0060135380.019
purine nucleotide metabolic processGO:00061632290.019
nucleobase containing compound catabolic processGO:00346551520.019
g protein coupled receptor signaling pathwayGO:00071862420.019
cellular response to starvationGO:0009267270.019
nucleoside monophosphate metabolic processGO:0009123930.019
positive regulation of cell motilityGO:2000147970.018
macromolecular complex subunit organizationGO:00439333390.018
neuron developmentGO:00486662860.018
cellular component assemblyGO:00226073600.018
protein catabolic processGO:0030163300.018
positive regulation of molecular functionGO:00440932300.018
protein homooligomerizationGO:0051260910.018
negative regulation of gene expressionGO:00106291990.018
negative regulation of cell communicationGO:00106481580.018
blood vessel morphogenesisGO:0048514580.018
regulation of response to external stimulusGO:00321011060.018
vesicle mediated transportGO:00161921810.018
rna biosynthetic processGO:00327743800.018
positive regulation of purine nucleotide metabolic processGO:1900544910.018
regulation of hydrolase activityGO:00513361430.017
cellular chemical homeostasisGO:00550822470.017
positive regulation of behaviorGO:0048520380.017
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.017
immune effector processGO:0002252530.017
Mouse
response to woundingGO:00096112540.017
peptidyl amino acid modificationGO:00181931260.017
cellular response to extracellular stimulusGO:0031668730.017
rna metabolic processGO:00160704060.017
monovalent inorganic cation transportGO:00156721720.017
purine nucleoside monophosphate metabolic processGO:0009126840.016
protein processingGO:0016485680.016
vasculature developmentGO:0001944700.016
negative regulation of innate immune responseGO:004582440.016
developmental process involved in reproductionGO:00030061590.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
positive regulation of cellular protein metabolic processGO:00322701670.016
negative regulation of macromolecule metabolic processGO:00106052600.015
gamete generationGO:00072761240.015
regulation of rna metabolic processGO:00512523910.015
acute inflammatory responseGO:0002526580.015
schwann cell migrationGO:003613520.015
intracellular transportGO:00469071850.015
negative regulation of cellular metabolic processGO:00313242810.015
epithelial cell proliferationGO:0050673540.015
response to mechanical stimulusGO:00096121340.015
establishment of vesicle localizationGO:0051650310.015
head developmentGO:00603222470.015
cellular response to abiotic stimulusGO:0071214850.015
ribose phosphate metabolic processGO:00196932350.015
adaptive immune responseGO:0002250140.014
Mouse
skeletal muscle tissue developmentGO:0007519310.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
reactive oxygen species metabolic processGO:0072593370.014
proteolysis involved in cellular protein catabolic processGO:0051603190.014
regulation of cellular localizationGO:00603412630.014
enzyme linked receptor protein signaling pathwayGO:00071671160.013
response to reactive oxygen speciesGO:00003021200.013
positive regulation of phosphorylationGO:00423271770.013
lymphocyte activationGO:0046649430.013
Mouse
leukocyte mediated cytotoxicityGO:0001909100.013
Mouse
regulation of synaptic transmissionGO:00508041410.012
positive regulation of cellular biosynthetic processGO:00313282950.012
development of primary sexual characteristicsGO:00451371070.012
negative regulation of defense responseGO:0031348190.012
negative regulation of leukocyte mediated immunityGO:000270460.012
negative regulation of cellular biosynthetic processGO:00313271610.012
peptide secretionGO:0002790860.012
ribonucleoside monophosphate catabolic processGO:0009158550.012
regulation of epithelial cell proliferationGO:0050678490.012
autophagic cell deathGO:004810240.012
positive regulation of apoptotic processGO:00430651540.012
cellular protein localizationGO:00346131220.012
response to ketoneGO:19016541820.012
activation of cysteine type endopeptidase activity involved in apoptotic processGO:000691940.012
cellular response to organonitrogen compoundGO:00714171970.012
regulation of defense responseGO:0031347680.012
positive regulation of fibroblast proliferationGO:0048146150.012
cellular response to mechanical stimulusGO:0071260480.011
regulation of immune effector processGO:0002697320.011
Mouse
reproductive system developmentGO:00614581280.011
positive regulation of biosynthetic processGO:00098913190.011
protein transportGO:00150311320.011
gonad developmentGO:00084061040.011
positive regulation of protein metabolic processGO:00512471780.011
regulation of neuron projection developmentGO:00109751610.011
purine ribonucleoside monophosphate metabolic processGO:0009167840.011
positive regulation of protein modification processGO:00314011420.011
central nervous system developmentGO:00074173110.011
chaperone mediated protein folding requiring cofactorGO:005108520.011
positive regulation of gene expressionGO:00106282440.011
growthGO:00400071650.010
regulation of angiogenesisGO:0045765390.010
purine containing compound catabolic processGO:00725231380.010
transcription from rna polymerase ii promoterGO:00063662520.010
cellular macromolecule catabolic processGO:0044265290.010
cell migrationGO:00164771970.010
behaviorGO:00076102050.010
regulation of endopeptidase activityGO:0052548510.010
metal ion transportGO:00300012890.010
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.010
glutamate receptor signaling pathwayGO:0007215430.010
purine containing compound metabolic processGO:00725212530.010
purine nucleoside monophosphate catabolic processGO:0009128550.010
ribonucleoside triphosphate metabolic processGO:00091991410.010
nucleoside triphosphate catabolic processGO:00091431230.010

B2m disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
primary immunodeficiency diseaseDOID:61200.082
hematopoietic system diseaseDOID:7400.082
blood protein diseaseDOID:62000.082
agammaglobulinemiaDOID:258300.082
b cell deficiencyDOID:211500.082
immune system diseaseDOID:291400.082
disease of anatomical entityDOID:700.082
nervous system diseaseDOID:86300.017
degeneration of macula and posterior poleDOID:200700.011
sensory system diseaseDOID:005015500.011
retinal degenerationDOID:846600.011
eye and adnexa diseaseDOID:149200.011
age related macular degenerationDOID:1087100.011
retinal diseaseDOID:567900.011
macular degenerationDOID:444800.011
eye diseaseDOID:561400.011