IMP: Integrative Multi-species Prediction

Rattus norvegicus

14 known processes

Unc50

unc-50 homolog (C. elegans)

(Aliases: Uncl)

RGD: 621749
Ensembl: ENSRNOG00000018128
Entrez: 192356
UniProtKB: O55227

Process Predictions
Disease Predictions

Unc50 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
nitrogen compound transport	GO:0071705	229	0.066
response to hypoxia	GO:0001666	231	0.059
reproductive process	GO:0022414	372	0.056
ion transmembrane transport	GO:0034220	365	0.052
behavior	GO:0007610	205	0.052
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.050
single organism reproductive process	GO:0044702	297	0.045
transmembrane transport	GO:0055085	412	0.039
oxidation reduction process	GO:0055114	304	0.038
positive regulation of cellular biosynthetic process	GO:0031328	295	0.037
regulation of hormone levels	GO:0010817	187	0.033
cellular response to growth factor stimulus	GO:0071363	162	0.032
regulation of phosphate metabolic process	GO:0019220	349	0.031
multicellular organism reproduction	GO:0032504	233	0.029
anion transport	GO:0006820	178	0.029
multi organism reproductive process	GO:0044703	262	0.028
organic acid transport	GO:0015849	116	0.028
carboxylic acid catabolic process	GO:0046395	49	0.028
organic acid catabolic process	GO:0016054	49	0.026
cellular response to endogenous stimulus	GO:0071495	377	0.026
cell cell signaling	GO:0007267	335	0.026
cation transport	GO:0006812	382	0.026
response to acid chemical	GO:0001101	222	0.026
programmed cell death	GO:0012501	392	0.025
response to decreased oxygen levels	GO:0036293	237	0.025
anion transmembrane transport	GO:0098656	77	0.025
cellular homeostasis	GO:0019725	252	0.024
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.024
positive regulation of biosynthetic process	GO:0009891	319	0.024
lipid metabolic process	GO:0006629	283	0.024
positive regulation of gene expression	GO:0010628	244	0.024
hormone transport	GO:0009914	121	0.023
carboxylic acid transport	GO:0046942	115	0.023
intracellular signal transduction	GO:0035556	314	0.022
organic acid metabolic process	GO:0006082	292	0.022
gamete generation	GO:0007276	124	0.022
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.021
single organism organelle organization	GO:1902589	180	0.021
organic cation transport	GO:0015695	11	0.021
reproduction	GO:0000003	245	0.021
cellular component assembly	GO:0022607	360	0.020
hormone secretion	GO:0046879	115	0.020
regulation of molecular function	GO:0065009	398	0.020
regulation of cellular component biogenesis	GO:0044087	86	0.019
amide transport	GO:0042886	105	0.019
homeostatic process	GO:0042592	331	0.019
blood circulation	GO:0008015	183	0.019
apoptotic process	GO:0006915	381	0.018
positive regulation of phosphorus metabolic process	GO:0010562	262	0.018
response to extracellular stimulus	GO:0009991	380	0.018
protein complex biogenesis	GO:0070271	263	0.018
multicellular organismal reproductive process	GO:0048609	233	0.018
transforming growth factor beta3 production	GO:0032907	2	0.018
transcription dna templated	GO:0006351	377	0.017
cellular response to oxygen containing compound	GO:1901701	386	0.017
negative regulation of apoptotic process	GO:0043066	181	0.017
cellular component biogenesis	GO:0044085	368	0.017
chemical homeostasis	GO:0048878	292	0.017
regulation of catalytic activity	GO:0050790	304	0.017
synaptic transmission	GO:0007268	235	0.017
bmp signaling pathway	GO:0030509	4	0.017
fatty acid transport	GO:0015908	25	0.016
rna metabolic process	GO:0016070	406	0.016
response to oxygen levels	GO:0070482	265	0.016
organelle organization	GO:0006996	266	0.016
regulation of apoptotic process	GO:0042981	335	0.016
neuron projection morphogenesis	GO:0048812	122	0.016
monocarboxylic acid transport	GO:0015718	52	0.016
lipid transport	GO:0006869	61	0.016
positive regulation of rna metabolic process	GO:0051254	203	0.016
regulation of phosphorus metabolic process	GO:0051174	349	0.016
positive regulation of transcription dna templated	GO:0045893	197	0.016
asymmetric protein localization	GO:0008105	2	0.015
response to growth factor	GO:0070848	189	0.015
spermatogenesis	GO:0007283	99	0.015
secretion	GO:0046903	307	0.015
regulation of transcription from rna polymerase ii promoter	GO:0006357	234	0.015
positive regulation of molecular function	GO:0044093	230	0.015
regulation of cellular component organization	GO:0051128	368	0.015
positive regulation of chemotaxis	GO:0050921	23	0.015
mullerian duct regression	GO:0001880	2	0.015
regulation of neurogenesis	GO:0050767	247	0.015
tissue development	GO:0009888	252	0.015
regulation of protein metabolic process	GO:0051246	289	0.015
rna biosynthetic process	GO:0032774	380	0.014
regulation of hydrolase activity	GO:0051336	143	0.014
regulation of multicellular organismal development	GO:2000026	376	0.014
regulation of anatomical structure size	GO:0090066	135	0.014
regulation of nucleic acid templated transcription	GO:1903506	380	0.014
positive regulation of cell death	GO:0010942	184	0.014
peptide secretion	GO:0002790	86	0.014
positive regulation of programmed cell death	GO:0043068	157	0.014
proteolysis	GO:0006508	175	0.014
positive regulation of cytokine production	GO:0001819	42	0.014
positive regulation of bone mineralization	GO:0030501	4	0.014
cellular lipid catabolic process	GO:0044242	37	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.014
nucleotide transmembrane transport	GO:1901679	2	0.014
transmission of nerve impulse	GO:0019226	42	0.013
carboxylic acid metabolic process	GO:0019752	289	0.013
fatty acid beta oxidation	GO:0006635	22	0.013
regulation of transforming growth factor beta3 production	GO:0032910	2	0.013
developmental process involved in reproduction	GO:0003006	159	0.013
positive regulation of cell communication	GO:0010647	271	0.013
peptide hormone secretion	GO:0030072	84	0.013
positive regulation of apoptotic process	GO:0043065	154	0.013
nucleic acid templated transcription	GO:0097659	379	0.013
action potential	GO:0001508	54	0.012
ossification	GO:0001503	70	0.012
protein complex subunit organization	GO:0071822	302	0.012
sexual reproduction	GO:0019953	148	0.012
positive regulation of catalytic activity	GO:0043085	184	0.012
positive regulation of focal adhesion assembly	GO:0051894	2	0.012
fatty acid oxidation	GO:0019395	29	0.012
regulation of response to external stimulus	GO:0032101	106	0.012
peptide transport	GO:0015833	97	0.012
positive regulation of biomineral tissue development	GO:0070169	4	0.012
regulation of rna metabolic process	GO:0051252	391	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	197	0.011
embryonic pattern specification	GO:0009880	1	0.011
positive regulation of protein metabolic process	GO:0051247	178	0.011
cell projection organization	GO:0030030	302	0.011
regulation of system process	GO:0044057	208	0.011
regulation of hormone secretion	GO:0046883	106	0.011
positive regulation of signaling	GO:0023056	270	0.011
negative regulation of cell death	GO:0060548	229	0.011
regulation of blood pressure	GO:0008217	83	0.011
cellular chemical homeostasis	GO:0055082	247	0.011
regulation of transcription dna templated	GO:0006355	374	0.011
male gamete generation	GO:0048232	99	0.011
regulation of secretion by cell	GO:1903530	208	0.011
cellular amine metabolic process	GO:0044106	38	0.011
regulation of cellular localization	GO:0060341	263	0.011
secretion by cell	GO:0032940	248	0.011
catabolic process	GO:0009056	351	0.011
response to estrogen	GO:0043627	232	0.010
positive regulation of cellular amine metabolic process	GO:0033240	3	0.010
response to nutrient levels	GO:0031667	370	0.010
macromolecular complex assembly	GO:0065003	273	0.010
protein processing	GO:0016485	68	0.010
insulin secretion	GO:0030073	69	0.010

Unc50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network