IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

RGD1562844

similar to serine (or cysteine) proteinase inhibitor, clade B, member 9

RGD: 1562844
Entrez: 306892

Process Predictions
Disease Predictions

RGD1562844 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
lipid metabolic process	GO:0006629	283	0.158
response to oxidative stress	GO:0006979	186	0.104
response to lipopolysaccharide	GO:0032496	191	0.101
anatomical structure morphogenesis	GO:0009653	298	0.096
steroid metabolic process	GO:0008202	73	0.084
cellular response to endogenous stimulus	GO:0071495	377	0.080
organic acid metabolic process	GO:0006082	292	0.073
negative regulation of response to tumor cell	GO:0002835	2	0.071
response to growth factor	GO:0070848	189	0.070
monocarboxylic acid transport	GO:0015718	52	0.069
tissue development	GO:0009888	252	0.069
response to estradiol	GO:0032355	164	0.067
regulation of protein metabolic process	GO:0051246	289	0.066
response to ionizing radiation	GO:0010212	59	0.066
response to ketone	GO:1901654	182	0.062
response to cytokine	GO:0034097	215	0.061
cellular response to oxygen containing compound	GO:1901701	386	0.057
kidney development	GO:0001822	67	0.056
mapk cascade	GO:0000165	140	0.056
negative regulation of natural killer cell mediated cytotoxicity	GO:0045953	4	0.054
response to molecule of bacterial origin	GO:0002237	194	0.052
positive regulation of biosynthetic process	GO:0009891	319	0.052
response to bacterium	GO:0009617	200	0.048
gland development	GO:0048732	155	0.047
organic substance catabolic process	GO:1901575	316	0.046
single organism biosynthetic process	GO:0044711	342	0.045
positive regulation of phosphate metabolic process	GO:0045937	262	0.045
positive regulation of programmed cell death	GO:0043068	157	0.045
protein oligomerization	GO:0051259	191	0.044
protein phosphorylation	GO:0006468	345	0.044
regulation of phosphate metabolic process	GO:0019220	349	0.044
response to reactive oxygen species	GO:0000302	120	0.043
cellular response to alcohol	GO:0097306	87	0.043
negative regulation of natural killer cell mediated immunity	GO:0002716	4	0.043
intracellular signal transduction	GO:0035556	314	0.042
regulation of phosphorus metabolic process	GO:0051174	349	0.042
regulation of cellular ketone metabolic process	GO:0010565	27	0.042
chemical homeostasis	GO:0048878	292	0.042
response to external biotic stimulus	GO:0043207	221	0.041
cellular catabolic process	GO:0044248	295	0.041
regulation of intracellular signal transduction	GO:1902531	218	0.041
macromolecular complex subunit organization	GO:0043933	339	0.039
rna metabolic process	GO:0016070	406	0.037
negative regulation of metabolic process	GO:0009892	331	0.037
regulation of phosphatidylinositol dephosphorylation	GO:0060304	1	0.036
programmed cell death	GO:0012501	392	0.036
regulation of signal transduction	GO:0009966	318	0.035
sterol catabolic process	GO:0016127	1	0.034
response to glucocorticoid	GO:0051384	223	0.034
apoptotic process	GO:0006915	381	0.034
regulation of phosphorylation	GO:0042325	248	0.033
natural killer cell mediated immune response to tumor cell	GO:0002423	1	0.033
regulation of homeostatic process	GO:0032844	101	0.032
negative regulation of response to stimulus	GO:0048585	155	0.032
response to peptide	GO:1901652	292	0.032
central nervous system development	GO:0007417	311	0.032
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.031
fatty acid metabolic process	GO:0006631	99	0.031
response to biotic stimulus	GO:0009607	226	0.031
response to nutrient levels	GO:0031667	370	0.031
regulation of molecular function	GO:0065009	398	0.030
lipid biosynthetic process	GO:0008610	128	0.030
negative regulation of innate immune response	GO:0045824	4	0.030
renal system development	GO:0072001	67	0.030
response to inorganic substance	GO:0010035	377	0.029
cellular ketone metabolic process	GO:0042180	51	0.029
cellular response to growth factor stimulus	GO:0071363	162	0.029
negative regulation of macromolecule metabolic process	GO:0010605	260	0.029
epithelial cell proliferation	GO:0050673	54	0.028
response to other organism	GO:0051707	220	0.028
cellular response to molecule of bacterial origin	GO:0071219	56	0.027
macromolecule localization	GO:0033036	252	0.027
oxidation reduction process	GO:0055114	304	0.027
detection of chemical stimulus involved in sensory perception of bitter taste	GO:0001580	4	0.026
negative regulation of biosynthetic process	GO:0009890	168	0.026
catabolic process	GO:0009056	351	0.026
regulation of cellular protein metabolic process	GO:0032268	267	0.026
positive regulation of cellular biosynthetic process	GO:0031328	295	0.026
regulation of secretion by cell	GO:1903530	208	0.026
regulation of cell proliferation	GO:0042127	359	0.026
positive regulation of developmental process	GO:0051094	283	0.025
cellular amino acid metabolic process	GO:0006520	107	0.025
head development	GO:0060322	247	0.025
cellular response to nitrogen compound	GO:1901699	210	0.025
regulation of lipid metabolic process	GO:0019216	68	0.025
organic hydroxy compound metabolic process	GO:1901615	115	0.025
oxoacid metabolic process	GO:0043436	290	0.025
multi organism reproductive process	GO:0044703	262	0.025
positive regulation of nervous system development	GO:0051962	178	0.024
circulatory system process	GO:0003013	183	0.024
nucleobase containing small molecule metabolic process	GO:0055086	316	0.024
tube development	GO:0035295	89	0.024
amine metabolic process	GO:0009308	38	0.024
positive regulation of cell development	GO:0010720	176	0.024
positive regulation of molecular function	GO:0044093	230	0.024
regulation of nervous system development	GO:0051960	264	0.024
cellular amine metabolic process	GO:0044106	38	0.024
positive regulation of cell proliferation	GO:0008284	249	0.023
cellular response to lipid	GO:0071396	201	0.023
protein homooligomerization	GO:0051260	91	0.023
regulation of cell development	GO:0060284	263	0.023
anion transport	GO:0006820	178	0.023
regulation of catalytic activity	GO:0050790	304	0.022
regulation of protein phosphorylation	GO:0001932	183	0.022
response to peptide hormone	GO:0043434	278	0.022
single organism organelle organization	GO:1902589	180	0.022
regulation of apoptotic process	GO:0042981	335	0.022
regulation of multicellular organismal development	GO:2000026	376	0.021
positive regulation of cell differentiation	GO:0045597	217	0.021
bile acid biosynthetic process	GO:0006699	3	0.021
response to radiation	GO:0009314	137	0.021
regulation of cellular amine metabolic process	GO:0033238	8	0.021
choline transport	GO:0015871	4	0.021
cellular response to stress	GO:0033554	269	0.021
response to estrogen	GO:0043627	232	0.020
wound healing	GO:0042060	122	0.020
calcium ion homeostasis	GO:0055074	162	0.020
carbohydrate derivative metabolic process	GO:1901135	346	0.020
response to blue light	GO:0009637	1	0.020
multicellular organism growth	GO:0035264	1	0.020
regulation of epithelial cell proliferation	GO:0050678	49	0.020
regulation of rna biosynthetic process	GO:2001141	381	0.020
reproduction	GO:0000003	245	0.020
metal ion transport	GO:0030001	289	0.020
response to transforming growth factor beta	GO:0071559	46	0.020
regulation of cell killing	GO:0031341	12	0.020
negative regulation of cellular metabolic process	GO:0031324	281	0.020
response to hexose	GO:0009746	144	0.020
cellular component biogenesis	GO:0044085	368	0.020
response to extracellular stimulus	GO:0009991	380	0.020
monocarboxylic acid metabolic process	GO:0032787	152	0.019
positive regulation of gene expression	GO:0010628	244	0.019
negative regulation of molecular function	GO:0044092	133	0.019
positive regulation of response to stimulus	GO:0048584	285	0.019
response to monosaccharide	GO:0034284	159	0.019
negative regulation of immune response to tumor cell	GO:0002838	2	0.019
steroid biosynthetic process	GO:0006694	48	0.019
jak stat cascade	GO:0007259	26	0.019
carboxylic acid biosynthetic process	GO:0046394	83	0.019
positive regulation of neurogenesis	GO:0050769	165	0.018
innate immune response	GO:0045087	35	0.018
protein processing	GO:0016485	68	0.018
ion homeostasis	GO:0050801	212	0.018
positive regulation of phosphorylation	GO:0042327	177	0.018
protein complex subunit organization	GO:0071822	302	0.018
response to corticosteroid	GO:0031960	235	0.018
protein complex biogenesis	GO:0070271	263	0.017
positive regulation of catalytic activity	GO:0043085	184	0.017
negative regulation of natural killer cell mediated immune response to tumor cell	GO:0002856	1	0.017
cellular lipid metabolic process	GO:0044255	208	0.017
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.017
organophosphate metabolic process	GO:0019637	370	0.017
purine ribonucleotide metabolic process	GO:0009150	227	0.017
regulation of cell motility	GO:2000145	131	0.017
secretion	GO:0046903	307	0.017
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.017
cellular response to hormone stimulus	GO:0032870	247	0.017
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.017
cytosolic calcium ion homeostasis	GO:0051480	140	0.017
regulation of cell differentiation	GO:0045595	320	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	161	0.017
signal transduction involved in regulation of gene expression	GO:0023019	4	0.016
cholesterol homeostasis	GO:0042632	3	0.016
response to acid chemical	GO:0001101	222	0.016
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090101	2	0.016
multicellular organismal reproductive process	GO:0048609	233	0.016
sensory perception of bitter taste	GO:0050913	4	0.016
urogenital system development	GO:0001655	78	0.016
cellular homeostasis	GO:0019725	252	0.016
homeostatic process	GO:0042592	331	0.016
regulation of cellular amino acid metabolic process	GO:0006521	2	0.016
proteolysis	GO:0006508	175	0.016
positive regulation of cellular amine metabolic process	GO:0033240	3	0.016
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.016
response to chromate	GO:0046687	3	0.016
regulation of transcription dna templated	GO:0006355	374	0.016
chlorinated hydrocarbon metabolic process	GO:0042196	4	0.016
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.016
response to carbohydrate	GO:0009743	183	0.016
cellular ion homeostasis	GO:0006873	184	0.015
cellular response to external stimulus	GO:0071496	118	0.015
negative regulation of cellular protein metabolic process	GO:0032269	106	0.015
ensheathment of neurons	GO:0007272	40	0.015
epithelium development	GO:0060429	96	0.015
negative regulation of transport	GO:0051051	136	0.015
cellular nitrogen compound catabolic process	GO:0044270	163	0.015
regulation of protein processing	GO:0070613	50	0.015
single organism intracellular transport	GO:1902582	166	0.015
nucleoside metabolic process	GO:0009116	179	0.015
cellular component assembly	GO:0022607	360	0.015
protein complex assembly	GO:0006461	263	0.015
regulation of programmed cell death	GO:0043067	341	0.015
positive regulation of cell death	GO:0010942	184	0.015
response to wounding	GO:0009611	254	0.015
macromolecular complex assembly	GO:0065003	273	0.015
insulin like growth factor receptor signaling pathway	GO:0048009	3	0.015
purine containing compound metabolic process	GO:0072521	253	0.015
positive regulation of phosphorus metabolic process	GO:0010562	262	0.015
glycosyl compound metabolic process	GO:1901657	182	0.015
divalent inorganic cation transport	GO:0072511	134	0.014
small molecule biosynthetic process	GO:0044283	124	0.014
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.014
negative regulation of gene expression	GO:0010629	199	0.014
establishment of synaptic specificity at neuromuscular junction	GO:0007529	1	0.014
g protein coupled receptor signaling pathway	GO:0007186	242	0.014
nucleoside phosphate metabolic process	GO:0006753	283	0.014
cellular response to lipopolysaccharide	GO:0071222	55	0.014
negative regulation of catalytic activity	GO:0043086	103	0.014
negative regulation of protein metabolic process	GO:0051248	114	0.014
carboxylic acid metabolic process	GO:0019752	289	0.014
response to hypoxia	GO:0001666	231	0.014
cellular response to cytokine stimulus	GO:0071345	127	0.014
response to interleukin 1	GO:0070555	55	0.014
regulation of hormone levels	GO:0010817	187	0.014
reactive oxygen species biosynthetic process	GO:1903409	8	0.014
calcium ion transport	GO:0006816	131	0.014
organ regeneration	GO:0031100	101	0.014
response to toxic substance	GO:0009636	133	0.014
negative regulation of cell proliferation	GO:0008285	119	0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway	GO:0090092	10	0.013
circadian rhythm	GO:0007623	88	0.013
female pregnancy	GO:0007565	122	0.013
transmission of nerve impulse	GO:0019226	42	0.013
regulation of neurogenesis	GO:0050767	247	0.013
regulation of bile acid biosynthetic process	GO:0070857	1	0.013
positive regulation of neuron differentiation	GO:0045666	126	0.013
blood circulation	GO:0008015	183	0.013
ribonucleotide metabolic process	GO:0009259	231	0.013
monocarboxylic acid biosynthetic process	GO:0072330	48	0.013
regulation of extracellular matrix constituent secretion	GO:0003330	2	0.013
negative regulation of viral process	GO:0048525	4	0.013
secretion by cell	GO:0032940	248	0.013
aging	GO:0007568	241	0.013
arachidonic acid metabolic process	GO:0019369	20	0.013
response to decreased oxygen levels	GO:0036293	237	0.013
regulation of cellular localization	GO:0060341	263	0.013
regulation of membrane potential	GO:0042391	110	0.013
protein transport	GO:0015031	132	0.013
regulation of anatomical structure morphogenesis	GO:0022603	141	0.013
protein catabolic process	GO:0030163	30	0.012
regulation of rna metabolic process	GO:0051252	391	0.012
negative regulation of rna metabolic process	GO:0051253	123	0.012
ribose phosphate metabolic process	GO:0019693	235	0.012
regulation of cellular component organization	GO:0051128	368	0.012
sterol homeostasis	GO:0055092	3	0.012
regulation of protein kinase activity	GO:0045859	105	0.012
regulation of mapk cascade	GO:0043408	116	0.012
purine nucleoside metabolic process	GO:0042278	169	0.012
purine ribonucleoside metabolic process	GO:0046128	168	0.012
cellular response to organonitrogen compound	GO:0071417	197	0.012
cell motility	GO:0048870	202	0.012
cellular response to reactive oxygen species	GO:0034614	55	0.012
regulation of peptidase activity	GO:0052547	55	0.012
epithelial cell proliferation involved in liver morphogenesis	GO:0072575	3	0.012
protein maturation	GO:0051604	68	0.012
respiratory system development	GO:0060541	45	0.012
cellular chemical homeostasis	GO:0055082	247	0.012
signal transduction by phosphorylation	GO:0023014	144	0.012
cellular calcium ion homeostasis	GO:0006874	160	0.012
regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	GO:0002858	1	0.012
antibiotic transport	GO:0042891	2	0.012
cellular response to oxidative stress	GO:0034599	76	0.012
regulation of natural killer cell mediated immune response to tumor cell	GO:0002855	1	0.012
connective tissue development	GO:0061448	33	0.012
response to vitamin	GO:0033273	131	0.012
positive regulation of cellular component organization	GO:0051130	200	0.012
regulation of cytokine biosynthetic process	GO:0042035	3	0.012
circulatory system development	GO:0072359	134	0.011
actin filament based process	GO:0030029	86	0.011
reactive nitrogen species metabolic process	GO:2001057	1	0.011
positive regulation of apoptotic process	GO:0043065	154	0.011
unsaturated fatty acid metabolic process	GO:0033559	39	0.011
nitrogen compound transport	GO:0071705	229	0.011
monovalent inorganic cation transport	GO:0015672	172	0.011
cell projection organization	GO:0030030	302	0.011
regulation of immunoglobulin production	GO:0002637	4	0.011
regulation of neurological system process	GO:0031644	43	0.011
single organism catabolic process	GO:0044712	283	0.011
lipid localization	GO:0010876	62	0.011
lipid transport	GO:0006869	61	0.011
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.011
positive regulation of neuron projection development	GO:0010976	99	0.011
lung development	GO:0030324	43	0.011
neuron differentiation	GO:0030182	368	0.011
salivary gland development	GO:0007431	3	0.011
response to camp	GO:0051591	91	0.011
response to organophosphorus	GO:0046683	102	0.011
cytoplasmic transport	GO:0016482	115	0.011
regulation of nucleic acid templated transcription	GO:1903506	380	0.011
rna biosynthetic process	GO:0032774	380	0.011
organic acid biosynthetic process	GO:0016053	83	0.011
transmembrane transport	GO:0055085	412	0.011
divalent metal ion transport	GO:0070838	132	0.011
phosphatidylinositol dephosphorylation	GO:0046856	4	0.011
renal system process	GO:0003014	40	0.011
rhythmic process	GO:0048511	156	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.010
positive regulation of multicellular organismal process	GO:0051240	387	0.010
regulation of lipid biosynthetic process	GO:0046890	38	0.010
response to testosterone	GO:0033574	55	0.010
small molecule catabolic process	GO:0044282	59	0.010
axis specification	GO:0009798	4	0.010
positive regulation of extracellular matrix constituent secretion	GO:0003331	2	0.010
regulation of reactive oxygen species biosynthetic process	GO:1903426	5	0.010
reproductive structure development	GO:0048608	128	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.010
regulation of kinase activity	GO:0043549	117	0.010

RGD1562844 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.015
	nervous system disease	DOID:863	0	0.015

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network