Rattus norvegicus

0 known processes

Tnfrsf12a

tumor necrosis factor receptor superfamily, member 12a

(Aliases: MGC72653,Fn14)

Tnfrsf12a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tissue developmentGO:00098882520.288
regulation of nucleic acid templated transcriptionGO:19035063800.219
programmed cell deathGO:00125013920.216
negative regulation of cell deathGO:00605482290.216
regulation of apoptotic processGO:00429813350.210
nucleic acid templated transcriptionGO:00976593790.199
cellular response to stressGO:00335542690.193
regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285810.150
positive regulation of cell proliferationGO:00082842490.145
neuron differentiationGO:00301823680.142
response to inorganic substanceGO:00100353770.139
response to oxidative stressGO:00069791860.138
response to decreased oxygen levelsGO:00362932370.136
apoptotic processGO:00069153810.135
response to hypoxiaGO:00016662310.128
head developmentGO:00603222470.126
transcription from rna polymerase ii promoterGO:00063662520.126
central nervous system developmentGO:00074173110.121
negative regulation of programmed cell deathGO:00430691830.112
transmembrane transportGO:00550854120.112
regulation of programmed cell deathGO:00430673410.103
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.101
response to hydrogen peroxideGO:0042542890.101
regulation of rna metabolic processGO:00512523910.097
response to oxygen levelsGO:00704822650.096
positive regulation of biosynthetic processGO:00098913190.095
regulation of transcription dna templatedGO:00063553740.094
response to corticosteroidGO:00319602350.093
regulation of natural killer cell mediated immune response to tumor cellGO:000285510.090
cellular response to endogenous stimulusGO:00714953770.087
negative regulation of apoptotic processGO:00430661810.085
epithelium developmentGO:0060429960.084
positive regulation of rna biosynthetic processGO:19026801970.083
natural killer cell mediated immune response to tumor cellGO:000242310.081
regulation of neuron apoptotic processGO:0043523830.078
ion transmembrane transportGO:00342203650.076
regulation of catalytic activityGO:00507903040.074
cell matrix adhesionGO:0007160190.074
cellular response to nitrogen compoundGO:19016992100.071
cellular response to oxygen containing compoundGO:19017013860.070
cell type specific apoptotic processGO:00972851340.068
regulation of rna biosynthetic processGO:20011413810.068
regulation of cell proliferationGO:00421273590.067
positive regulation of signalingGO:00230562700.065
response to woundingGO:00096112540.065
cellular response to oxidative stressGO:0034599760.065
response to estrogenGO:00436272320.064
response to extracellular stimulusGO:00099913800.064
positive regulation of cellular biosynthetic processGO:00313282950.063
response to other organismGO:00517072200.063
response to nutrientGO:00075842480.063
regulation of cell differentiationGO:00455953200.061
positive regulation of rna metabolic processGO:00512542030.061
response to reactive oxygen speciesGO:00003021200.060
positive regulation of nucleic acid templated transcriptionGO:19035081970.060
response to growth factorGO:00708481890.058
regulation of signal transductionGO:00099663180.057
neuron developmentGO:00486662860.057
intracellular signal transductionGO:00355563140.057
reproductive processGO:00224143720.056
gland developmentGO:00487321550.056
response to peptideGO:19016522920.054
single organism reproductive processGO:00447022970.053
regenerationGO:00310991630.053
response to tumor cellGO:000234740.052
response to nutrient levelsGO:00316673700.052
multicellular organism reproductionGO:00325042330.051
response to mechanical stimulusGO:00096121340.050
positive regulation of intracellular signal transductionGO:19025331380.049
protein phosphorylationGO:00064683450.048
carbohydrate derivative metabolic processGO:19011353460.047
positive regulation of macromolecule biosynthetic processGO:00105572470.046
signal transduction by phosphorylationGO:00230141440.046
negative regulation of cell proliferationGO:00082851190.046
rna metabolic processGO:00160704060.046
positive regulation of cell communicationGO:00106472710.045
cellular response to steroid hormone stimulusGO:0071383930.045
rna biosynthetic processGO:00327743800.045
anatomical structure morphogenesisGO:00096532980.044
single organism organelle organizationGO:19025891800.043
response to metal ionGO:00100382530.041
positive regulation of molecular functionGO:00440932300.041
immune response to tumor cellGO:000241830.041
positive regulation of phosphate metabolic processGO:00459372620.041
regulation of transcription from rna polymerase ii promoterGO:00063572340.040
negative regulation of response to stimulusGO:00485851550.040
cellular response to organic cyclic compoundGO:00714072020.039
positive regulation of phosphorylationGO:00423271770.039
positive regulation of response to stimulusGO:00485842850.039
carboxylic acid transportGO:00469421150.039
brain developmentGO:00074202470.038
macromolecular complex subunit organizationGO:00439333390.038
negative regulation of molecular functionGO:00440921330.037
negative regulation of biosynthetic processGO:00098901680.037
neuron deathGO:00709971270.037
positive regulation of developmental processGO:00510942830.037
response to glucocorticoidGO:00513842230.036
regulation of phosphorus metabolic processGO:00511743490.035
cellular response to organonitrogen compoundGO:00714171970.035
cellular catabolic processGO:00442482950.035
circulatory system processGO:00030131830.034
cation transportGO:00068123820.034
positive regulation of transcription dna templatedGO:00458931970.034
single organism catabolic processGO:00447122830.034
protein complex assemblyGO:00064612630.034
cell migrationGO:00164771970.034
cellular response to peptideGO:19016531330.034
defense responseGO:00069521940.033
single organism carbohydrate metabolic processGO:00447231180.033
cell cycleGO:00070491010.033
positive regulation of gene expressionGO:00106282440.033
regulation of molecular functionGO:00650093980.033
reproductive structure developmentGO:00486081280.032
transcription dna templatedGO:00063513770.032
wound healingGO:00420601220.032
organic acid metabolic processGO:00060822920.032
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.032
positive regulation of protein phosphorylationGO:00019341350.031
biological adhesionGO:00226101100.031
positive regulation of protein modification processGO:00314011420.031
cellular ketone metabolic processGO:0042180510.031
regulation of smooth muscle cell proliferationGO:0048660750.031
heart contractionGO:0060047570.031
regulation of defense responseGO:0031347680.031
negative regulation of cellular metabolic processGO:00313242810.031
regulation of response to stressGO:00801341260.031
cellular response to external stimulusGO:00714961180.030
cellular response to oxygen levelsGO:0071453600.030
growthGO:00400071650.030
negative regulation of gene expressionGO:00106291990.029
positive regulation of apoptotic processGO:00430651540.029
negative regulation of macromolecule biosynthetic processGO:00105581480.029
immune system processGO:00023762040.029
negative regulation of metabolic processGO:00098923310.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
actin cytoskeleton organizationGO:0030036730.028
response to acid chemicalGO:00011012220.028
gliogenesisGO:0042063930.027
muscle cell proliferationGO:0033002840.027
response to external biotic stimulusGO:00432072210.027
cellular response to growth factor stimulusGO:00713631620.027
positive regulation of fibroblast proliferationGO:0048146150.026
protein heterooligomerizationGO:0051291890.026
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.026
response to interleukin 1GO:0070555550.026
regulation of protein metabolic processGO:00512462890.026
regulation of intracellular signal transductionGO:19025312180.026
positive regulation of cell deathGO:00109421840.025
regulation of ion transportGO:00432692450.025
reproductionGO:00000032450.025
oxoacid metabolic processGO:00434362900.025
negative regulation of macromolecule metabolic processGO:00106052600.025
multi multicellular organism processGO:00447061380.025
nucleotide metabolic processGO:00091172790.025
nitrogen compound transportGO:00717052290.025
nucleobase containing small molecule metabolic processGO:00550863160.025
maternal process involved in female pregnancyGO:0060135380.025
positive regulation of nitrogen compound metabolic processGO:00511733340.025
positive regulation of signal transductionGO:00099671750.025
positive regulation of smooth muscle cell proliferationGO:0048661510.024
gastrulationGO:000736920.024
reproductive system developmentGO:00614581280.024
positive regulation of mesenchymal cell proliferationGO:000205340.024
single organism biosynthetic processGO:00447113420.024
response to transition metal nanoparticleGO:19902671220.024
organelle organizationGO:00069962660.024
positive regulation of cellular amino acid metabolic processGO:004576410.024
positive regulation of t cell mediated cytotoxicityGO:000191640.023
cellular response to hormone stimulusGO:00328702470.023
muscle tissue developmentGO:0060537580.023
agingGO:00075682410.023
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.023
cellular component assemblyGO:00226073600.023
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.023
positive regulation of catalytic activityGO:00430851840.023
cellular amine metabolic processGO:0044106380.023
actin filament based processGO:0030029860.022
carboxylic acid metabolic processGO:00197522890.022
organic anion transportGO:00157111320.022
neuron apoptotic processGO:0051402880.022
response to ketoneGO:19016541820.022
positive regulation of immune system processGO:0002684900.022
cellular response to reactive oxygen speciesGO:0034614550.022
smooth muscle cell proliferationGO:0048659770.022
striated muscle tissue developmentGO:0014706580.022
regulation of cellular protein metabolic processGO:00322682670.021
regulation of protein modification processGO:00313991940.021
macromolecular complex assemblyGO:00650032730.021
chemical homeostasisGO:00488782920.021
response to peptide hormoneGO:00434342780.021
positive regulation of programmed cell deathGO:00430681570.021
neuron projection developmentGO:00311752730.021
regulation of cellular component organizationGO:00511283680.021
cardiovascular system developmentGO:00723581340.021
cation transmembrane transportGO:00986552630.020
ribonucleotide metabolic processGO:00092592310.020
amine metabolic processGO:0009308380.020
cell cell signalingGO:00072673350.020
anion transportGO:00068201780.020
blood circulationGO:00080151830.020
negative regulation of cellular biosynthetic processGO:00313271610.019
regulation of cellular ketone metabolic processGO:0010565270.019
catabolic processGO:00090563510.019
multi organism reproductive processGO:00447032620.019
developmental growthGO:00485891000.019
small gtpase mediated signal transductionGO:0007264360.019
regulation of cell cycleGO:0051726730.019
positive regulation of cell differentiationGO:00455972170.019
response to vitaminGO:00332731310.019
response to hexoseGO:00097461440.019
negative regulation of cellular protein metabolic processGO:00322691060.019
cell cycle processGO:0022402570.019
protein oligomerizationGO:00512591910.019
mesoderm developmentGO:000749820.019
regulation of phosphate metabolic processGO:00192203490.019
cellular response to corticosteroid stimulusGO:0071384690.019
protein complex biogenesisGO:00702712630.018
response to purine containing compoundGO:00140741260.018
protein complex subunit organizationGO:00718223020.018
response to organophosphorusGO:00466831020.018
positive regulation of nervous system developmentGO:00519621780.018
response to toxic substanceGO:00096361330.018
regulation of cellular amine metabolic processGO:003323880.018
negative regulation of nucleic acid templated transcriptionGO:19035071170.018
circulatory system developmentGO:00723591340.018
cold acclimationGO:000963110.018
positive regulation of cell developmentGO:00107201760.018
forebrain developmentGO:0030900980.018
organ regenerationGO:00311001010.018
regulation of nervous system developmentGO:00519602640.018
single organism cellular localizationGO:19025801020.018
positive regulation of neuron deathGO:1901216430.018
ribose phosphate metabolic processGO:00196932350.017
carbohydrate metabolic processGO:00059751300.017
cell adhesionGO:00071551100.017
regulation of carbohydrate catabolic processGO:0043470140.017
regulation of metal ion transportGO:00109591180.017
regulation of neurogenesisGO:00507672470.017
negative regulation of transcription dna templatedGO:00458921160.017
regulation of ion transmembrane transportGO:00347651210.017
negative regulation of cell communicationGO:00106481580.017
gonad developmentGO:00084061040.017
cellular response to extracellular stimulusGO:0031668730.017
hepaticobiliary system developmentGO:0061008900.017
cellular component biogenesisGO:00440853680.017
negative regulation of multicellular organismal processGO:00512412030.017
positive regulation of phosphorus metabolic processGO:00105622620.017
regulation of cellular localizationGO:00603412630.017
reactive oxygen species metabolic processGO:0072593370.017
regulation of cell developmentGO:00602842630.017
divalent metal ion transportGO:00708381320.017
negative regulation of transportGO:00510511360.017
intracellular transportGO:00469071850.017
developmental process involved in reproductionGO:00030061590.016
liver developmentGO:0001889900.016
homeostatic processGO:00425923310.016
muscle system processGO:00030121150.016
positive regulation of neurogenesisGO:00507691650.016
heart processGO:0003015570.016
plasminogen activationGO:003163920.016
dna metabolic processGO:0006259960.016
glucose homeostasisGO:0042593750.016
cofactor metabolic processGO:0051186950.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
multicellular organismal reproductive processGO:00486092330.016
positive regulation of cellular amine metabolic processGO:003324030.016
positive regulation of transportGO:00510502450.016
regulation of neuron deathGO:19012141150.016
regulation of kinase activityGO:00435491170.016
development of primary sexual characteristicsGO:00451371070.016
lipid metabolic processGO:00066292830.016
hemostasisGO:0007599260.016
cell substrate adhesionGO:0031589290.016
keratinocyte migrationGO:005154620.016
regulation of endothelial cell apoptotic processGO:200035130.016
heart morphogenesisGO:000300730.016
small molecule biosynthetic processGO:00442831240.015
cellular homeostasisGO:00197252520.015
cellular response to hypoxiaGO:0071456510.015
ras protein signal transductionGO:0007265290.015
carbohydrate derivative biosynthetic processGO:19011371240.015
nucleoside phosphate metabolic processGO:00067532830.015
female gonad developmentGO:0008585530.015
muscle structure developmentGO:0061061870.015
regulation of immune system processGO:00026821230.015
localization of cellGO:00516742020.015
monosaccharide metabolic processGO:0005996610.015
coagulationGO:0050817280.015
response to high density lipoprotein particleGO:005509920.015
cellular response to lipidGO:00713962010.015
organophosphate metabolic processGO:00196373700.015
response to starvationGO:0042594590.015
regulation of cell projection organizationGO:00313441750.015
positive regulation of protein metabolic processGO:00512471780.015
regulation of phosphorylationGO:00423252480.015
muscle organ developmentGO:0007517500.015
ossificationGO:0001503700.015
regulation of cellular amino acid metabolic processGO:000652120.015
locomotionGO:00400112370.015
cytoskeleton organizationGO:00070101110.014
response to amino acidGO:0043200750.014
female pregnancyGO:00075651220.014
response to cycloheximideGO:004689860.014
synapse assemblyGO:0007416290.014
positive regulation of neuron apoptotic processGO:0043525330.014
purine nucleotide metabolic processGO:00061632290.014
cellular response to insulin stimulusGO:0032869810.014
leukocyte mediated immunityGO:0002443280.014
oxidation reduction processGO:00551143040.014
organic substance catabolic processGO:19015753160.014
skeletal muscle organ developmentGO:0060538330.014
dendrite developmentGO:0016358720.014
programmed necrotic cell deathGO:009730020.014
response to bacteriumGO:00096172000.014
angiogenesisGO:0001525530.014
positive regulation of natural killer cell mediated cytotoxicityGO:004595420.014
cytoplasmic transportGO:00164821150.013
epithelial cell differentiationGO:0030855710.013
single organism intracellular transportGO:19025821660.013
positive regulation of cellular component organizationGO:00511302000.013
response to estradiolGO:00323551640.013
cellular response to hydrogen peroxideGO:0070301420.013
hexose metabolic processGO:0019318580.013
anterior posterior pattern specificationGO:000995210.013
organophosphate biosynthetic processGO:00904071430.013
regulation of protein phosphorylationGO:00019321830.013
regulation of purine nucleotide metabolic processGO:19005421150.013
positive regulation of cell migrationGO:0030335960.013
positive regulation of response to woundingGO:1903036340.013
positive regulation of transferase activityGO:0051347810.013
response to monosaccharideGO:00342841590.013
positive regulation of cellular protein metabolic processGO:00322701670.013
positive regulation of natural killer cell mediated immunityGO:000271720.013
regulation of cell motilityGO:20001451310.013
mapk cascadeGO:00001651400.013
response to ethanolGO:00454711620.013
dephosphorylationGO:0016311980.012
regulation of multicellular organismal developmentGO:20000263760.012
formation of primary germ layerGO:000170410.012
skeletal muscle tissue developmentGO:0007519310.012
muscle cell differentiationGO:0042692520.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
multicellular organismal signalingGO:0035637440.012
cellular component morphogenesisGO:00329891550.012
gamete generationGO:00072761240.012
purine containing compound metabolic processGO:00725212530.012
cellular response to alcoholGO:0097306870.012
dendrite morphogenesisGO:0048813430.012
secretion by cellGO:00329402480.012
female sex differentiationGO:0046660590.012
negative regulation of signalingGO:00230571570.012
cell growthGO:00160491040.012
development of primary female sexual characteristicsGO:0046545560.012
negative regulation of protein metabolic processGO:00512481140.012
autophagic cell deathGO:004810240.012
regulation of system processGO:00440572080.012
metal ion transportGO:00300012890.012
response to cgmpGO:007030530.012
male gamete generationGO:0048232990.012
negative regulation of rna metabolic processGO:00512531230.012
cellular response to glucocorticoid stimulusGO:0071385680.012
immune responseGO:00069551040.012
regulation of response to external stimulusGO:00321011060.012
regulation of cell adhesionGO:0030155520.012
axis specificationGO:000979840.012
urogenital system developmentGO:0001655780.012
nucleocytoplasmic transportGO:0006913480.012
cellular amino acid metabolic processGO:00065201070.012
regulation of transmembrane transportGO:00347621220.012
proteolysisGO:00065081750.012
response to biotic stimulusGO:00096072260.012
regulation of cellular component biogenesisGO:0044087860.012
regulation of response to woundingGO:1903034690.012
muscle contractionGO:0006936880.012
blood vessel developmentGO:0001568690.011
sex differentiationGO:00075481130.011
purine ribonucleotide metabolic processGO:00091502270.011
apoptotic signaling pathwayGO:0097190270.011
regulation of intracellular transportGO:0032386650.011
cell part morphogenesisGO:00329901230.011
negative regulation of cell differentiationGO:0045596990.011
cellular response to metal ionGO:0071248550.011
purine ribonucleoside metabolic processGO:00461281680.011
cellular response to mechanical stimulusGO:0071260480.011
amino acid transportGO:0006865700.011
cytokine productionGO:0001816610.011
negative regulation of developmental processGO:00510931250.011
cellular response to abiotic stimulusGO:0071214850.011
regulation of synaptic transmissionGO:00508041410.011
wound healing spreading of cellsGO:004431920.011
regulation of hydrolase activityGO:00513361430.011
regulation of reactive oxygen species biosynthetic processGO:190342650.011
regulation of neuron differentiationGO:00456642080.011
cellular response to carbohydrate stimulusGO:0071322720.011
positive regulation of neuron differentiationGO:00456661260.011
organonitrogen compound biosynthetic processGO:19015661670.011
regulation of proteasomal protein catabolic processGO:006113640.011
regulation of protein localizationGO:0032880810.011
collecting duct developmentGO:007204410.011
negative regulation of peptidase activityGO:0010466380.011
endothelial cell apoptotic processGO:007257730.010
cellular response to inorganic substanceGO:0071241650.010
glial cell differentiationGO:0010001650.010
cell projection organizationGO:00300303020.010
positive regulation of ion transportGO:0043270940.010
regulation of body fluid levelsGO:0050878900.010
positive regulation of t cell mediated immunityGO:000271140.010
regulation of blood circulationGO:19035221100.010
response to molecule of bacterial originGO:00022371940.010
negative regulation of osteoblast differentiationGO:004566820.010
lipid storageGO:001991510.010
positive regulation of mapk cascadeGO:0043410920.010

Tnfrsf12a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
nervous system diseaseDOID:86300.038
charcot marie tooth diseaseDOID:1059500.038
neuromuscular diseaseDOID:44000.038
neuropathyDOID:87000.038
musculoskeletal system diseaseDOID:1700.020
muscular diseaseDOID:008000000.020
muscle tissue diseaseDOID:6600.020
myopathyDOID:42300.020
cardiovascular system diseaseDOID:128700.019
dilated cardiomyopathyDOID:1293000.019
cardiomyopathyDOID:005070000.019
intrinsic cardiomyopathyDOID:006003600.019
heart diseaseDOID:11400.019
central nervous system diseaseDOID:33100.018
integumentary system diseaseDOID:1600.014
lipodystrophyDOID:81100.014
skin diseaseDOID:3700.014
charcot marie tooth disease type 2DOID:005053900.013