Rattus norvegicus

92 known processes

Col2a1

collagen, type II, alpha 1

(Aliases: CG2A1A,COLLII)

Col2a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tissue developmentGO:00098882520.290
cellular response to oxygen containing compoundGO:19017013860.275
cellular response to endogenous stimulusGO:00714953770.180
response to extracellular stimulusGO:00099913800.163
cellular response to peptide hormone stimulusGO:00713751200.160
cellular chemical homeostasisGO:00550822470.139
response to oxygen levelsGO:00704822650.136
Rat
response to nutrient levelsGO:00316673700.124
central nervous system developmentGO:00074173110.120
gland developmentGO:00487321550.115
response to peptide hormoneGO:00434342780.110
response to hypoxiaGO:00016662310.110
response to radiationGO:00093141370.106
regulation of system processGO:00440572080.104
nucleic acid templated transcriptionGO:00976593790.100
anatomical structure morphogenesisGO:00096532980.099
response to nutrientGO:00075842480.098
negative regulation of cell deathGO:00605482290.089
cellular response to hormone stimulusGO:00328702470.087
cell cell signalingGO:00072673350.086
regulation of nucleic acid templated transcriptionGO:19035063800.083
cellular response to peptideGO:19016531330.081
neurological system processGO:00508772190.079
Human
cellular amino acid metabolic processGO:00065201070.079
chemical homeostasisGO:00488782920.076
reproductive processGO:00224143720.074
response to peptideGO:19016522920.067
cellular homeostasisGO:00197252520.067
transcription dna templatedGO:00063513770.066
secretionGO:00469033070.064
positive regulation of signal transductionGO:00099671750.064
regulation of rna metabolic processGO:00512523910.061
epithelium developmentGO:0060429960.059
response to metal ionGO:00100382530.058
brain developmentGO:00074202470.058
positive regulation of signalingGO:00230562700.056
cell morphogenesis involved in differentiationGO:00009041190.056
regulation of rna biosynthetic processGO:20011413810.055
regulation of multicellular organismal developmentGO:20000263760.054
response to corticosteroidGO:00319602350.054
Rat
response to inorganic substanceGO:00100353770.052
Rat
regulation of programmed cell deathGO:00430673410.052
response to decreased oxygen levelsGO:00362932370.052
single organism behaviorGO:00447081300.052
negative regulation of macromolecule biosynthetic processGO:00105581480.050
cellular response to organic cyclic compoundGO:00714072020.050
multicellular organismal reproductive processGO:00486092330.050
cellular response to stressGO:00335542690.049
chemosensory behaviorGO:000763520.049
programmed cell deathGO:00125013920.049
negative regulation of multicellular organismal processGO:00512412030.048
regulation of apoptotic processGO:00429813350.047
neuron differentiationGO:00301823680.047
rna metabolic processGO:00160704060.046
multi multicellular organism processGO:00447061380.046
intracellular signal transductionGO:00355563140.046
positive regulation of nitrogen compound metabolic processGO:00511733340.045
regulation of transcription from rna polymerase ii promoterGO:00063572340.045
regulation of transcription dna templatedGO:00063553740.044
regulation of secretion by cellGO:19035302080.044
cell projection organizationGO:00300303020.044
response to bacteriumGO:00096172000.043
regulation of nervous system developmentGO:00519602640.043
rna biosynthetic processGO:00327743800.043
adult locomotory behaviorGO:000834440.043
intracellular transportGO:00469071850.043
regulation of signal transductionGO:00099663180.042
single organism reproductive processGO:00447022970.042
multi organism reproductive processGO:00447032620.042
regulation of cell proliferationGO:00421273590.041
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.040
cell morphogenesisGO:00009021420.040
regenerationGO:00310991630.040
reproductionGO:00000032450.039
protein phosphorylationGO:00064683450.039
ion homeostasisGO:00508012120.039
developmental process involved in reproductionGO:00030061590.039
olfactory behaviorGO:004204820.039
cellular response to lipidGO:00713962010.038
cell adhesionGO:00071551100.038
skeletal system developmentGO:0001501410.038
cellular response to acid chemicalGO:0071229750.038
embryonic skeletal system morphogenesisGO:004870430.038
Human
axon developmentGO:0061564960.038
circadian rhythmGO:0007623880.038
negative regulation of response to stimulusGO:00485851550.038
cellular cation homeostasisGO:00300031800.038
rhythmic processGO:00485111560.038
transmission of nerve impulseGO:0019226420.038
neuron projection developmentGO:00311752730.038
carbohydrate derivative metabolic processGO:19011353460.037
negative regulation of programmed cell deathGO:00430691830.037
behaviorGO:00076102050.037
ossificationGO:0001503700.037
Rat
homeostatic processGO:00425923310.037
ion transmembrane transportGO:00342203650.036
regulation of circadian sleep wake cycle sleepGO:0045187180.036
regulation of cell differentiationGO:00455953200.035
olfactory learningGO:000835510.035
positive regulation of response to stimulusGO:00485842850.035
organ morphogenesisGO:0009887750.035
regulation of molecular functionGO:00650093980.035
positive regulation of biosynthetic processGO:00098913190.035
cellular component biogenesisGO:00440853680.034
cation transmembrane transportGO:00986552630.034
regulation of phosphorus metabolic processGO:00511743490.034
cation transportGO:00068123820.033
negative regulation of biosynthetic processGO:00098901680.033
response to estradiolGO:00323551640.033
Rat
cellular component movementGO:00069282480.032
positive regulation of multicellular organismal processGO:00512403870.032
cellular component morphogenesisGO:00329891550.032
head developmentGO:00603222470.032
response to biotic stimulusGO:00096072260.032
secretion by cellGO:00329402480.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.031
oxoacid metabolic processGO:00434362900.031
multicellular organismal signalingGO:0035637440.031
positive regulation of transcription dna templatedGO:00458931970.030
regulation of neurogenesisGO:00507672470.030
response to insulinGO:00328681330.030
response to transition metal nanoparticleGO:19902671220.030
organic acid metabolic processGO:00060822920.030
cellular response to organonitrogen compoundGO:00714171970.029
positive regulation of gene expressionGO:00106282440.029
single organism intracellular transportGO:19025821660.029
synaptic transmissionGO:00072682350.029
response to retinoic acidGO:0032526630.029
response to temperature stimulusGO:0009266940.029
positive regulation of nervous system developmentGO:00519621780.028
response to growth factorGO:00708481890.028
negative regulation of neurogenesisGO:0050768780.028
salivary gland developmentGO:000743130.028
connective tissue developmentGO:0061448330.028
eye morphogenesisGO:004859240.027
negative regulation of gene expressionGO:00106291990.027
developmental growthGO:00485891000.027
negative regulation of signalingGO:00230571570.027
response to axon injuryGO:0048678590.027
positive regulation of cellular protein metabolic processGO:00322701670.027
gliogenesisGO:0042063930.027
cartilage developmentGO:0051216220.027
positive regulation of cell communicationGO:00106472710.027
growthGO:00400071650.027
neuron developmentGO:00486662860.026
purine nucleotide metabolic processGO:00061632290.026
regulation of cell developmentGO:00602842630.026
regulation of membrane potentialGO:00423911100.026
regulation of intracellular signal transductionGO:19025312180.026
carboxylic acid metabolic processGO:00197522890.026
negative regulation of cell communicationGO:00106481580.026
protein oligomerizationGO:00512591910.026
positive regulation of cell differentiationGO:00455972170.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
organ regenerationGO:00311001010.025
positive regulation of intracellular signal transductionGO:19025331380.024
negative regulation of cell developmentGO:0010721820.024
negative regulation of macromolecule metabolic processGO:00106052600.024
apoptotic processGO:00069153810.024
positive regulation of rna metabolic processGO:00512542030.024
regulation of neuron apoptotic processGO:0043523830.024
positive regulation of neurogenesisGO:00507691650.024
metal ion homeostasisGO:00550651860.024
sexual reproductionGO:00199531480.023
negative regulation of cellular biosynthetic processGO:00313271610.023
negative regulation of metabolic processGO:00098923310.023
cellular response to growth factor stimulusGO:00713631620.023
Rat
liver developmentGO:0001889900.023
metal ion transportGO:00300012890.023
cell morphogenesis involved in neuron differentiationGO:00486671060.023
response to glucocorticoidGO:00513842230.023
negative regulation of apoptotic processGO:00430661810.023
macromolecular complex assemblyGO:00650032730.023
axis specificationGO:000979840.023
regulation of cellular component organizationGO:00511283680.022
positive regulation of phosphorylationGO:00423271770.022
regulation of metal ion transportGO:00109591180.022
epithelial cell differentiationGO:0030855710.022
negative regulation of transcription dna templatedGO:00458921160.022
neuronal action potentialGO:0019228350.022
neuron deathGO:00709971270.022
response to acid chemicalGO:00011012220.022
reproductive structure developmentGO:00486081280.021
anatomical structure formation involved in morphogenesisGO:0048646830.021
locomotionGO:00400112370.021
muscle system processGO:00030121150.021
biological adhesionGO:00226101100.021
positive regulation of kinase activityGO:0033674770.021
regulation of phosphorylationGO:00423252480.021
response to molecule of bacterial originGO:00022371940.021
agingGO:00075682410.021
Rat
cell projection morphogenesisGO:00488581230.021
nucleobase containing small molecule metabolic processGO:00550863160.021
salivary gland morphogenesisGO:000743510.021
establishment of protein localizationGO:00451841410.021
regulation of neuron differentiationGO:00456642080.021
single organism biosynthetic processGO:00447113420.021
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.021
nitrogen compound transportGO:00717052290.021
sensory organ developmentGO:0007423740.021
regulation of protein phosphorylationGO:00019321830.020
enzyme linked receptor protein signaling pathwayGO:00071671160.020
response to hexoseGO:00097461440.020
regulation of mapk cascadeGO:00434081160.020
regulation of catalytic activityGO:00507903040.020
cellular ion homeostasisGO:00068731840.020
negative regulation of nucleic acid templated transcriptionGO:19035071170.020
cellular response to nicotineGO:007131670.020
organonitrogen compound biosynthetic processGO:19015661670.020
negative regulation of cellular metabolic processGO:00313242810.020
positive regulation of molecular functionGO:00440932300.020
cellular component assemblyGO:00226073600.020
organic cyclic compound catabolic processGO:19013611750.020
cellular amine metabolic processGO:0044106380.020
organic hydroxy compound metabolic processGO:19016151150.019
regulation of cellular protein metabolic processGO:00322682670.019
positive regulation of catalytic activityGO:00430851840.019
nucleoside phosphate metabolic processGO:00067532830.019
regulation of cellular localizationGO:00603412630.019
cytoplasmic transportGO:00164821150.019
amine metabolic processGO:0009308380.019
glucose homeostasisGO:0042593750.019
purine ribonucleotide metabolic processGO:00091502270.019
circulatory system processGO:00030131830.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.019
organelle organizationGO:00069962660.019
glial cell differentiationGO:0010001650.019
negative regulation of rna biosynthetic processGO:19026791180.019
cellular divalent inorganic cation homeostasisGO:00725031620.018
cation homeostasisGO:00550801950.018
regulation of hormone levelsGO:00108171870.018
regulation of cellular amine metabolic processGO:003323880.018
positive regulation of protein metabolic processGO:00512471780.018
regulation of synaptic transmissionGO:00508041410.018
positive regulation of protein modification processGO:00314011420.018
organonitrogen compound catabolic processGO:19015651790.018
positive regulation of protein phosphorylationGO:00019341350.018
response to alkaloidGO:00432791320.018
positive regulation of phosphorus metabolic processGO:00105622620.018
negative regulation of rna metabolic processGO:00512531230.018
response to estrogenGO:00436272320.018
Rat
anion transportGO:00068201780.018
transmembrane transportGO:00550854120.017
response to woundingGO:00096112540.017
Rat
negative regulation of nervous system developmentGO:0051961790.017
positive regulation of mapk cascadeGO:0043410920.017
female pregnancyGO:00075651220.017
nuclear transportGO:0051169490.017
neuron projection morphogenesisGO:00488121220.017
multicellular organism reproductionGO:00325042330.017
camera type eye morphogenesisGO:004859320.017
positive regulation of cellular biosynthetic processGO:00313282950.017
blood circulationGO:00080151830.017
axonogenesisGO:0007409710.017
response to monosaccharideGO:00342841590.017
cellular response to insulin stimulusGO:0032869810.017
circadian regulation of gene expressionGO:003292230.017
neuron apoptotic processGO:0051402880.017
positive regulation of cellular component organizationGO:00511302000.017
organophosphate catabolic processGO:00464341480.017
wnt signaling pathway planar cell polarity pathwayGO:006007120.017
regulation of phosphate metabolic processGO:00192203490.016
single organism catabolic processGO:00447122830.016
circadian sleep wake cycle processGO:0022410210.016
negative regulation of signal transductionGO:0009968830.016
sequestering of calcium ionGO:005120880.016
negative regulation of nucleobase containing compound metabolic processGO:00459341530.016
cellular response to nitrogen compoundGO:19016992100.016
g protein coupled receptor internalizationGO:000203130.016
response to external biotic stimulusGO:00432072210.016
learning or memoryGO:0007611900.016
cell growthGO:00160491040.016
positive regulation of cell developmentGO:00107201760.016
sensory perceptionGO:00076001010.016
Human
bone developmentGO:0060348250.016
purine containing compound metabolic processGO:00725212530.016
cellular calcium ion homeostasisGO:00068741600.016
cellular metal ion homeostasisGO:00068751720.016
neuron fate commitmentGO:004866340.016
cell part morphogenesisGO:00329901230.016
ribonucleotide metabolic processGO:00092592310.015
response to fluorideGO:190261730.015
Rat
hepaticobiliary system developmentGO:0061008900.015
protein complex biogenesisGO:00702712630.015
response to light stimulusGO:0009416520.015
peptide secretionGO:0002790860.015
cartilage development involved in endochondral bone morphogenesisGO:006035130.015
regulation of secretionGO:00510462240.015
cellular response to cytokine stimulusGO:00713451270.015
cellular response to oxidative stressGO:0034599760.015
protein transportGO:00150311320.015
spinal cord developmentGO:0021510270.015
response to cytokineGO:00340972150.015
negative regulation of canonical wnt signaling pathwayGO:009009040.015
cellular response to glucocorticoid stimulusGO:0071385680.015
embryonic pattern specificationGO:000988010.015
macromolecular complex subunit organizationGO:00439333390.015
Human
inorganic ion transmembrane transportGO:00986602290.015
cell junction maintenanceGO:003433110.015
morphogenesis of a polarized epitheliumGO:000173810.015
regulation of cellular amino acid metabolic processGO:000652120.015
cytoskeleton dependent cytokinesisGO:006164020.014
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
vesicle mediated transportGO:00161921810.014
gamete generationGO:00072761240.014
response to purine containing compoundGO:00140741260.014
Rat
positive regulation of phosphate metabolic processGO:00459372620.014
synaptic transmission dopaminergicGO:0001963110.014
negative regulation of nitrogen compound metabolic processGO:00511721610.014
carbohydrate homeostasisGO:0033500750.014
negative regulation of cell differentiationGO:0045596990.014
limb morphogenesisGO:003510840.014
monocarboxylic acid transportGO:0015718520.014
negative regulation of developmental processGO:00510931250.014
wound healingGO:00420601220.014
Rat
cellular modified amino acid metabolic processGO:0006575610.014
regulation of homeostatic processGO:00328441010.014
organophosphate metabolic processGO:00196373700.014
inorganic cation transmembrane transportGO:00986622020.014
cellular response to hexose stimulusGO:0071331650.014
response to oxidative stressGO:00069791860.014
Rat
positive regulation of apoptotic processGO:00430651540.014
cellular lipid metabolic processGO:00442552080.014
g protein coupled receptor signaling pathwayGO:00071862420.014
response to mechanical stimulusGO:00096121340.014
peptidyl tyrosine phosphorylationGO:0018108720.014
calcium ion homeostasisGO:00550741620.014
circadian sleep wake cycleGO:0042745230.014
regulation of canonical wnt signaling pathwayGO:006082840.014
negative regulation of neuron apoptotic processGO:0043524450.014
embryonic skeletal system developmentGO:004870630.014
Human
positive regulation of rna biosynthetic processGO:19026801970.013
regulation of blood circulationGO:19035221100.013
response to x rayGO:0010165150.013
regulation of protein modification processGO:00313991940.013
cytosolic calcium ion homeostasisGO:00514801400.013
defense responseGO:00069521940.013
spermatogenesisGO:0007283990.013
protein complex subunit organizationGO:00718223020.013
Human
proteolysisGO:00065081750.013
response to other organismGO:00517072200.013
sex differentiationGO:00075481130.013
sensory perception of painGO:0019233730.013
cognitionGO:0050890920.013
regulation of establishment of protein localizationGO:0070201690.013
regulation of protein metabolic processGO:00512462890.013
positive regulation of secretionGO:00510471400.013
reproductive system developmentGO:00614581280.013
single organism cell adhesionGO:0098602460.013
nucleotide metabolic processGO:00091172790.013
actin filament based processGO:0030029860.013
positive regulation of neuron differentiationGO:00456661260.013
heterocycle catabolic processGO:00467001670.012
single organism carbohydrate metabolic processGO:00447231180.012
regulation of cytokine productionGO:0001817560.012
response to lipopolysaccharideGO:00324961910.012
response to ethanolGO:00454711620.012
regulation of protein transportGO:0051223680.012
regulation of synaptic plasticityGO:0048167700.012
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.012
transcription from rna polymerase ii promoterGO:00063662520.012
cellular response to carbohydrate stimulusGO:0071322720.012
positive regulation of protein kinase activityGO:0045860730.012
hormone metabolic processGO:0042445690.012
rhythmic behaviorGO:0007622240.012
negative regulation of molecular functionGO:00440921330.012
nucleoside catabolic processGO:00091641260.012
monovalent inorganic cation transportGO:00156721720.012
positive regulation of programmed cell deathGO:00430681570.012
negative regulation of cell proliferationGO:00082851190.012
endochondral bone growthGO:000341630.012
cell motilityGO:00488702020.012
negative regulation of neuron deathGO:1901215690.012
developmental maturationGO:0021700250.012
peptide hormone secretionGO:0030072840.012
negative regulation of cell cycle phase transitionGO:190198840.012
tube developmentGO:0035295890.012
purine nucleotide catabolic processGO:00061951360.012
male gamete generationGO:0048232990.012
response to campGO:0051591910.012
Rat
carbohydrate derivative catabolic processGO:19011361470.012
regulation of ion transportGO:00432692450.012
macromolecule localizationGO:00330362520.012
response to carbohydrateGO:00097431830.012
regulation of neuron deathGO:19012141150.011
regulation of growthGO:00400081050.011
lipid transportGO:0006869610.011
cellular macromolecule localizationGO:00707271220.011
retina development in camera type eyeGO:0060041270.011
protein localizationGO:00081041910.011
regulation of notch signaling pathwayGO:000859330.011
embryo developmentGO:0009790490.011
Human Zebrafish
protein complex assemblyGO:00064612630.011
regulation of purine nucleotide metabolic processGO:19005421150.011
regulation of circadian sleep wake cycleGO:0042749180.011
amine transportGO:0015837570.011
protein maturationGO:0051604680.011
single organism cellular localizationGO:19025801020.011
male mating behaviorGO:006017930.011
cellular amide metabolic processGO:0043603440.011
multicellular organism growthGO:003526410.011
skeletal muscle cell differentiationGO:003591420.011
regulation of peptide secretionGO:0002791820.011
regulation of response to stressGO:00801341260.011
regulation of cell motilityGO:20001451310.011
carboxylic acid transportGO:00469421150.011
regulation of cell cycleGO:0051726730.011
cellular response to glucose stimulusGO:0071333650.011
photoperiodismGO:000964840.011
regulation of cell morphogenesisGO:0022604770.011
rho protein signal transductionGO:0007266110.011
nucleoside metabolic processGO:00091161790.011
locomotory behaviorGO:0007626150.011
response to tumor necrosis factorGO:0034612560.011
metanephric comma shaped body morphogenesisGO:007227820.011
protein heterooligomerizationGO:0051291890.011
circulatory system developmentGO:00723591340.011
cellular response to corticosteroid stimulusGO:0071384690.011
single organism organelle organizationGO:19025891800.011
divalent inorganic cation homeostasisGO:00725071650.011
carbohydrate derivative biosynthetic processGO:19011371240.011
cell cycle checkpointGO:000007520.010
catabolic processGO:00090563510.010
peptidyl amino acid modificationGO:00181931260.010
calcium ion importGO:0070509220.010
sensory perception of light stimulusGO:005095330.010
Human
palate developmentGO:006002120.010
skeletal system morphogenesisGO:0048705120.010
cellular response to monosaccharide stimulusGO:0071326670.010
regulation of neuronal synaptic plasticityGO:0048168310.010
sequestering of metal ionGO:005123890.010
carboxylic acid biosynthetic processGO:0046394830.010
ribose phosphate biosynthetic processGO:0046390870.010
localization of cellGO:00516742020.010
signal releaseGO:00230611450.010
heart processGO:0003015570.010
embryonic appendage morphogenesisGO:003511340.010
growth plate cartilage developmentGO:000341720.010
small gtpase mediated signal transductionGO:0007264360.010

Col2a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.150
Human
disease of anatomical entityDOID:700.150
Human
nervous system diseaseDOID:86300.062
connective tissue diseaseDOID:6500.046
Human
bone development diseaseDOID:008000600.046
Human
bone diseaseDOID:008000100.046
Human
urinary system diseaseDOID:1800.028
kidney diseaseDOID:55700.028
osteochondrodysplasiaDOID:225600.027
Human
gastrointestinal system diseaseDOID:7700.017
muscle tissue diseaseDOID:6600.016
muscular diseaseDOID:008000000.016
neuropathyDOID:87000.016
disease of metabolismDOID:001466700.016
eye diseaseDOID:561400.015
retinal diseaseDOID:567900.015
retinal degenerationDOID:846600.015
eye and adnexa diseaseDOID:149200.015
sensory system diseaseDOID:005015500.015
inherited metabolic disorderDOID:65500.014
neuromuscular diseaseDOID:44000.014
disease of cellular proliferationDOID:1456600.014
charcot marie tooth diseaseDOID:1059500.012