Rattus norvegicus

0 known processes

Ppy

pancreatic polypeptide

Ppy biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to extracellular stimulusGO:00099913800.395
Rat
nitrogen compound transportGO:00717052290.377
reproductive processGO:00224143720.349
regulation of membrane potentialGO:00423911100.285
developmental process involved in reproductionGO:00030061590.270
regulation of cellular ketone metabolic processGO:0010565270.265
regulation of multicellular organismal developmentGO:20000263760.261
response to woundingGO:00096112540.246
single organism reproductive processGO:00447022970.239
cellular component biogenesisGO:00440853680.217
oxoacid metabolic processGO:00434362900.207
macromolecular complex assemblyGO:00650032730.207
regulation of cellular component organizationGO:00511283680.193
regulation of blood pressureGO:0008217830.188
Rat
carboxylic acid metabolic processGO:00197522890.180
cell projection organizationGO:00300303020.172
neuron developmentGO:00486662860.165
anatomical structure morphogenesisGO:00096532980.165
chemical homeostasisGO:00488782920.160
response to lipopolysaccharideGO:00324961910.159
protein complex assemblyGO:00064612630.158
locomotionGO:00400112370.158
neuron differentiationGO:00301823680.156
positive regulation of multicellular organismal processGO:00512403870.148
neuron projection developmentGO:00311752730.147
cellular component assemblyGO:00226073600.146
monovalent inorganic cation transportGO:00156721720.145
protein complex biogenesisGO:00702712630.141
heart contractionGO:0060047570.140
response to nutrient levelsGO:00316673700.139
Rat
reproductive system developmentGO:00614581280.131
behaviorGO:00076102050.130
Rat
multicellular organism reproductionGO:00325042330.129
reproductive structure developmentGO:00486081280.127
multi organism reproductive processGO:00447032620.126
transmembrane transportGO:00550854120.123
regulation of cell proliferationGO:00421273590.122
ion transmembrane transportGO:00342203650.120
negative regulation of metabolic processGO:00098923310.120
ion homeostasisGO:00508012120.119
protein oligomerizationGO:00512591910.117
organic acid transportGO:00158491160.117
negative regulation of response to woundingGO:1903035230.117
organic anion transportGO:00157111320.112
carboxylic acid transportGO:00469421150.109
cellular response to organonitrogen compoundGO:00714171970.107
cation transportGO:00068123820.107
regulation of secretionGO:00510462240.106
secretionGO:00469033070.104
response to oxidative stressGO:00069791860.102
development of primary sexual characteristicsGO:00451371070.101
single organism organelle organizationGO:19025891800.101
response to cytokineGO:00340972150.101
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.100
renal system processGO:0003014400.098
single organism behaviorGO:00447081300.096
Rat
cell cell signalingGO:00072673350.094
Rat
sensory perceptionGO:00076001010.092
Rat
negative regulation of response to external stimulusGO:0032102370.090
Rat
multi multicellular organism processGO:00447061380.090
hormone secretionGO:00468791150.090
regulation of cellular protein metabolic processGO:00322682670.089
response to foodGO:0032094270.089
Rat
brain developmentGO:00074202470.088
regulation of neuron differentiationGO:00456642080.087
multicellular organismal reproductive processGO:00486092330.085
blood circulationGO:00080151830.085
Rat
axon developmentGO:0061564960.084
regulation of appetiteGO:003209880.084
Rat
homeostatic processGO:00425923310.082
regulation of nucleic acid templated transcriptionGO:19035063800.082
response to oxygen levelsGO:00704822650.081
purine ribonucleotide metabolic processGO:00091502270.081
head developmentGO:00603222470.080
circulatory system processGO:00030131830.080
Rat
protein complex subunit organizationGO:00718223020.079
inflammatory responseGO:00069541500.078
gland developmentGO:00487321550.077
regulation of cellular component movementGO:00512701500.075
negative regulation of multicellular organismal processGO:00512412030.075
regulation of molecular functionGO:00650093980.075
positive regulation of long term synaptic potentiationGO:190027340.075
catabolic processGO:00090563510.072
cellular component movementGO:00069282480.072
response to molecule of bacterial originGO:00022371940.071
organic substance catabolic processGO:19015753160.070
regulation of neuron projection developmentGO:00109751610.070
response to mechanical stimulusGO:00096121340.070
learning or memoryGO:0007611900.070
regulation of blood vessel sizeGO:0050880890.070
cellular response to endogenous stimulusGO:00714953770.069
positive regulation of cellular biosynthetic processGO:00313282950.068
immune system processGO:00023762040.067
regulation of protein metabolic processGO:00512462890.067
transcription from rna polymerase ii promoterGO:00063662520.066
response to organophosphorusGO:00466831020.065
regulation of response to external stimulusGO:00321011060.064
Rat
regulation of camp metabolic processGO:0030814430.064
forebrain developmentGO:0030900980.064
action potentialGO:0001508540.064
secretion by cellGO:00329402480.064
urinary bladder smooth muscle contractionGO:001483240.064
cellular response to stressGO:00335542690.063
response to peptideGO:19016522920.063
regulation of cellular amine metabolic processGO:003323880.063
response to inorganic substanceGO:00100353770.063
carbohydrate derivative biosynthetic processGO:19011371240.061
regulation of cellular amino acid metabolic processGO:000652120.061
cellular amine metabolic processGO:0044106380.061
single organism catabolic processGO:00447122830.060
regulation of secretion by cellGO:19035302080.060
organelle organizationGO:00069962660.060
cytoskeleton organizationGO:00070101110.059
cation transmembrane transportGO:00986552630.059
negative regulation of nitrogen compound metabolic processGO:00511721610.059
macromolecular complex subunit organizationGO:00439333390.059
response to toxic substanceGO:00096361330.059
reproductionGO:00000032450.058
lipid metabolic processGO:00066292830.058
protein phosphorylationGO:00064683450.058
sodium ion transportGO:0006814820.057
amide transportGO:00428861050.057
cell morphogenesis involved in differentiationGO:00009041190.056
negative regulation of cellular metabolic processGO:00313242810.056
regulation of peptide transportGO:0090087870.056
synaptic transmissionGO:00072682350.056
Rat
regulation of cell developmentGO:00602842630.055
negative regulation of response to stimulusGO:00485851550.055
Rat
metal ion transportGO:00300012890.053
growthGO:00400071650.053
carbohydrate derivative metabolic processGO:19011353460.053
regulation of anatomical structure sizeGO:00900661350.052
response to biotic stimulusGO:00096072260.051
limb morphogenesisGO:003510840.051
cellular ion homeostasisGO:00068731840.051
hormone transportGO:00099141210.051
regulation of synaptic transmissionGO:00508041410.051
defense responseGO:00069521940.050
cellular ketone metabolic processGO:0042180510.050
response to alkaloidGO:00432791320.050
positive regulation of protein metabolic processGO:00512471780.050
response to glucocorticoidGO:00513842230.049
regulation of defense responseGO:0031347680.048
cell morphogenesis involved in neuron differentiationGO:00486671060.048
regulation of wound healingGO:0061041140.047
cellular lipid metabolic processGO:00442552080.046
limbic system developmentGO:0021761380.045
regulation of response to woundingGO:1903034690.044
negative regulation of developmental processGO:00510931250.044
cognitionGO:0050890920.044
cellular amino acid metabolic processGO:00065201070.043
regenerationGO:00310991630.043
digestionGO:0007586260.043
response to metal ionGO:00100382530.043
response to mineralocorticoidGO:0051385490.043
regulation of cardiac muscle tissue developmentGO:0055024120.043
regulation of epithelial cell differentiationGO:0030856120.043
cellular response to nitrogen compoundGO:19016992100.042
regulation of ion transmembrane transporter activityGO:0032412480.042
regulation of hormone levelsGO:00108171870.042
positive regulation of phosphorylationGO:00423271770.042
response to nutrientGO:00075842480.042
response to estrogenGO:00436272320.042
central nervous system developmentGO:00074173110.041
regulation of the force of heart contraction by chemical signalGO:000305720.041
biological adhesionGO:00226101100.041
amine metabolic processGO:0009308380.041
positive regulation of gene expressionGO:00106282440.041
regulation of catalytic activityGO:00507903040.041
cellular response to abiotic stimulusGO:0071214850.041
positive regulation of rna metabolic processGO:00512542030.040
circulatory system developmentGO:00723591340.040
positive regulation of nervous system developmentGO:00519621780.040
odontogenesisGO:0042476320.040
forebrain generation of neuronsGO:002187280.040
regulation of peptide secretionGO:0002791820.040
gonad developmentGO:00084061040.040
tissue developmentGO:00098882520.039
proteolysisGO:00065081750.039
regulation of cell projection organizationGO:00313441750.039
transcription dna templatedGO:00063513770.039
positive regulation of biosynthetic processGO:00098913190.039
heart morphogenesisGO:000300730.038
peptide transportGO:0015833970.038
regulation of rna biosynthetic processGO:20011413810.038
acute inflammatory responseGO:0002526580.038
positive regulation of molecular functionGO:00440932300.038
response to corticosteroidGO:00319602350.038
positive regulation of protein phosphorylationGO:00019341350.037
urinary tract smooth muscle contractionGO:001484840.037
organophosphate biosynthetic processGO:00904071430.037
regulation of blood circulationGO:19035221100.037
response to vitaminGO:00332731310.037
positive regulation of nitrogen compound metabolic processGO:00511733340.036
multicellular organismal response to stressGO:0033555250.036
wound healingGO:00420601220.035
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.035
memoryGO:0007613540.035
localization of cellGO:00516742020.034
regulation of signal transductionGO:00099663180.034
appendage morphogenesisGO:003510740.033
anion transportGO:00068201780.033
organic acid metabolic processGO:00060822920.033
regulation of transcription dna templatedGO:00063553740.033
anterior posterior pattern specificationGO:000995210.033
response to tumor necrosis factorGO:0034612560.033
smooth muscle contractionGO:0006939370.033
hippocampus developmentGO:0021766300.033
organic hydroxy compound metabolic processGO:19016151150.032
organonitrogen compound biosynthetic processGO:19015661670.032
cell migrationGO:00164771970.032
cellular response to hormone stimulusGO:00328702470.032
forebrain neuron differentiationGO:002187970.032
negative regulation of signalingGO:00230571570.032
organophosphate metabolic processGO:00196373700.032
negative regulation of cell differentiationGO:0045596990.032
gamete generationGO:00072761240.031
regulation of behaviorGO:0050795610.031
macromolecule catabolic processGO:0009057580.031
digestive system processGO:0022600240.031
sensory organ developmentGO:0007423740.031
camp biosynthetic processGO:0006171470.031
agingGO:00075682410.031
regulation of systemic arterial blood pressureGO:0003073300.031
response to transition metal nanoparticleGO:19902671220.030
response to nicotineGO:0035094510.030
regulation of body fluid levelsGO:0050878900.030
axon regenerationGO:0031103280.030
positive regulation of heart contractionGO:0045823150.030
mesoderm developmentGO:000749820.030
neuron projection regenerationGO:0031102350.030
negative regulation of cellular biosynthetic processGO:00313271610.030
vasoconstrictionGO:0042310540.030
negative regulation of response to foodGO:003209670.030
Rat
negative regulation of biosynthetic processGO:00098901680.029
regulation of growthGO:00400081050.029
protein localizationGO:00081041910.029
purine nucleotide metabolic processGO:00061632290.029
sexual reproductionGO:00199531480.029
regulation of heart rateGO:0002027160.029
positive regulation of cellular protein metabolic processGO:00322701670.029
peptide secretionGO:0002790860.029
positive regulation of cell proliferationGO:00082842490.028
signal releaseGO:00230611450.028
protein heterooligomerizationGO:0051291890.028
response to temperature stimulusGO:0009266940.028
cellular catabolic processGO:00442482950.028
regulation of ion transportGO:00432692450.028
regulation of apoptotic processGO:00429813350.028
nucleic acid templated transcriptionGO:00976593790.027
positive regulation of rna biosynthetic processGO:19026801970.027
heart developmentGO:0007507720.027
regulation of system processGO:00440572080.027
response to purine containing compoundGO:00140741260.026
embryonic appendage morphogenesisGO:003511340.026
negative regulation of blood pressureGO:0045776290.026
Rat
regulation of saliva secretionGO:004687730.026
negative regulation of molecular functionGO:00440921330.026
vascular process in circulatory systemGO:0003018960.026
nucleotide metabolic processGO:00091172790.026
eye developmentGO:0001654500.025
positive regulation of macromolecule biosynthetic processGO:00105572470.025
positive regulation of cell differentiationGO:00455972170.025
camp metabolic processGO:0046058630.025
positive regulation of cell communicationGO:00106472710.025
regulation of anion transportGO:0044070430.025
apoptotic processGO:00069153810.025
response to corticosteroneGO:0051412400.025
positive regulation of cellular amino acid metabolic processGO:004576410.025
negative regulation of transportGO:00510511360.025
response to ketoneGO:19016541820.025
regulation of protein modification processGO:00313991940.025
purine nucleotide biosynthetic processGO:0006164830.025
smooth muscle cell proliferationGO:0048659770.025
response to peptide hormoneGO:00434342780.024
positive regulation of developmental processGO:00510942830.024
regulation of rna metabolic processGO:00512523910.024
cellular component morphogenesisGO:00329891550.024
positive regulation of phosphate metabolic processGO:00459372620.024
organ morphogenesisGO:0009887750.024
monocarboxylic acid metabolic processGO:00327871520.024
macromolecule localizationGO:00330362520.024
positive regulation of the force of heart contraction by norepinephrineGO:000306110.024
intracellular signal transductionGO:00355563140.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
metanephric s shaped body morphogenesisGO:007228420.023
eye morphogenesisGO:004859240.023
sex differentiationGO:00075481130.023
programmed cell deathGO:00125013920.023
response to hypoxiaGO:00016662310.023
regulation of response to stressGO:00801341260.023
response to ethanolGO:00454711620.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
positive regulation of cell developmentGO:00107201760.023
regulation of pancreatic stellate cell proliferationGO:200022920.023
regulation of transferase activityGO:00513381230.023
ras protein signal transductionGO:0007265290.022
developmental growthGO:00485891000.022
cellular response to lipidGO:00713962010.022
oxidation reduction processGO:00551143040.022
response to external biotic stimulusGO:00432072210.022
telencephalon developmentGO:0021537620.022
positive regulation of programmed cell deathGO:00430681570.022
regulation of vasoconstrictionGO:0019229440.022
placenta developmentGO:0001890220.022
vitamin a metabolic processGO:000677620.022
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.021
positive regulation of cellular component organizationGO:00511302000.021
carbohydrate metabolic processGO:00059751300.021
regulation of programmed cell deathGO:00430673410.021
dendrite developmentGO:0016358720.021
embryonic limb morphogenesisGO:003032640.021
neurological system processGO:00508772190.021
Rat
chemosensory behaviorGO:000763520.021
protein homooligomerizationGO:0051260910.021
response to amino acidGO:0043200750.021
positive regulation of apoptotic processGO:00430651540.021
ribose phosphate metabolic processGO:00196932350.020
glial cell differentiationGO:0010001650.020
negative regulation of phosphorus metabolic processGO:0010563800.020
synaptic transmission glutamatergicGO:0035249330.020
cell part morphogenesisGO:00329901230.020
positive regulation of response to woundingGO:1903036340.020
negative regulation of gene expressionGO:00106291990.020
camera type eye morphogenesisGO:004859320.020
cell morphogenesisGO:00009021420.020
nucleotide biosynthetic processGO:0009165980.020
membrane depolarizationGO:0051899320.020
positive regulation of blood circulationGO:1903524650.020
positive regulation of protein modification processGO:00314011420.019
astrocyte differentiationGO:0048708190.019
regulation of phosphorylationGO:00423252480.019
regulation of purine nucleotide biosynthetic processGO:1900371460.019
positive regulation of secretionGO:00510471400.019
cellular response to oxygen containing compoundGO:19017013860.019
negative regulation of nucleobase containing compound metabolic processGO:00459341530.019
camera type eye developmentGO:0043010480.019
peptide hormone secretionGO:0030072840.019
response to ammonium ionGO:0060359710.019
negative regulation of intracellular estrogen receptor signaling pathwayGO:003314720.019
phototransduction visible lightGO:000760320.019
transmission of nerve impulseGO:0019226420.019
brain renin angiotensin systemGO:000203530.019
regulation of metal ion transportGO:00109591180.019
muscle system processGO:00030121150.019
peptidyl amino acid modificationGO:00181931260.019
regulation of phosphate metabolic processGO:00192203490.019
positive regulation of catalytic activityGO:00430851840.019
positive regulation of renin secretion into blood streamGO:190013510.019
positive regulation of peptide hormone secretionGO:0090277500.019
intestinal absorptionGO:005089230.019
regulation of tube sizeGO:0035150890.019
neuron projection morphogenesisGO:00488121220.019
positive regulation of the force of heart contraction by chemical signalGO:000309920.019
cellular response to fluid shear stressGO:007149840.018
negative regulation of cell deathGO:00605482290.018
positive regulation of hepatocyte differentiationGO:007036820.018
saliva secretionGO:004654130.018
rhythmic processGO:00485111560.018
positive regulation of synaptic transmissionGO:0050806620.018
cell motilityGO:00488702020.018
regulation of protein serine threonine kinase activityGO:0071900640.018
regulation of homeostatic processGO:00328441010.018
reactive nitrogen species metabolic processGO:200105710.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
positive regulation of catabolic processGO:0009896780.018
g protein coupled receptor signaling pathwayGO:00071862420.018
Rat
n methyl d aspartate receptor clusteringGO:009711420.018
negative regulation of transcription regulatory region dna bindingGO:200067820.017
rna metabolic processGO:00160704060.017
sodium ion transmembrane transportGO:0035725670.017
detection of abiotic stimulusGO:0009582130.017
intracellular receptor signaling pathwayGO:0030522350.017
positive regulation of cellular amine metabolic processGO:003324030.017
lipid transportGO:0006869610.017
negative regulation of cell communicationGO:00106481580.017
cyclic nucleotide metabolic processGO:0009187800.017
nucleotide catabolic processGO:00091661390.017
positive regulation of cell projection organizationGO:00313461110.017
phospholipase c activating serotonin receptor signaling pathwayGO:000720820.017
regulation of insulin secretionGO:0050796650.017
small molecule biosynthetic processGO:00442831240.017
heart processGO:0003015570.017
embryonic pattern specificationGO:000988010.017
regulation of locomotionGO:00400121480.017
response to vitamin eGO:0033197240.017
tube developmentGO:0035295890.017
response to hexoseGO:00097461440.017
regulation of protein homodimerization activityGO:004349650.017
negative regulation of transcription dna templatedGO:00458921160.017
catecholamine transportGO:0051937370.017
acid secretionGO:0046717480.017
purine containing compound metabolic processGO:00725212530.016
regulation of nervous system developmentGO:00519602640.016
regulation of intracellular signal transductionGO:19025312180.016
fear responseGO:004259690.016
positive regulation of signalingGO:00230562700.016
epithelium developmentGO:0060429960.016
positive regulation of ion transportGO:0043270940.016
behavioral response to nicotineGO:003509520.016
fatty acid metabolic processGO:0006631990.016
nucleobase containing small molecule metabolic processGO:00550863160.016
sensory perception of painGO:0019233730.016
negative regulation of macromolecule metabolic processGO:00106052600.016
organic hydroxy compound transportGO:0015850770.016
positive regulation of signal transductionGO:00099671750.016
single organism biosynthetic processGO:00447113420.016
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.016
insulin secretionGO:0030073690.016
response to axon injuryGO:0048678590.016
regulation of fat cell differentiationGO:004559830.016
positive regulation of the force of heart contraction by epinephrineGO:000305910.016
organonitrogen compound catabolic processGO:19015651790.016
neuropeptide signaling pathwayGO:0007218290.016
Rat
adrenergic receptor signaling pathwayGO:007187590.016
diaphragm contractionGO:000208620.016
negative regulation of macromolecule biosynthetic processGO:00105581480.016
purine containing compound biosynthetic processGO:0072522850.016
feeding behaviorGO:0007631530.016
Rat
retina development in camera type eyeGO:0060041270.016
potassium ion transportGO:0006813970.016
regulation of peptide hormone secretionGO:0090276800.015
gastrulationGO:000736920.015
multicellular organismal signalingGO:0035637440.015
striated muscle contractionGO:0006941440.015
muscle contractionGO:0006936880.015
positive regulation of neuron differentiationGO:00456661260.015
cellular nitrogen compound catabolic processGO:00442701630.015
regulation of protein kinase activityGO:00458591050.015
regulation of reactive oxygen species biosynthetic processGO:190342650.015
response to light stimulusGO:0009416520.015
behavioral response to cocaineGO:004814860.015
regulation of hormone secretionGO:00468831060.015
positive regulation of response to external stimulusGO:0032103510.015
Rat
regulation of cellular catabolic processGO:00313291010.015
negative regulation of nervous system developmentGO:0051961790.015
cell cycleGO:00070491010.015
pancreatic stellate cell proliferationGO:007234320.015
positive regulation of transferase activityGO:0051347810.015
response to estradiolGO:00323551640.015
regulation of neurogenesisGO:00507672470.015
organic cyclic compound catabolic processGO:19013611750.015
muscle structure developmentGO:0061061870.015
cellular chemical homeostasisGO:00550822470.015
cellular response to organic cyclic compoundGO:00714072020.015
monocarboxylic acid transportGO:0015718520.015
respiratory system processGO:000301630.014
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.014
negative regulation of neurogenesisGO:0050768780.014
detection of visible lightGO:000958430.014
calcium ion homeostasisGO:00550741620.014
negative regulation of catalytic activityGO:00430861030.014
spermatogenesisGO:0007283990.014
regulation of heart contractionGO:0008016480.014
carbohydrate derivative catabolic processGO:19011361470.014
negative regulation of response to extracellular stimulusGO:003210570.014
Rat
response to antibioticGO:0046677390.014
negative regulation of uterine smooth muscle contractionGO:007047320.014
cell adhesionGO:00071551100.014
negative regulation of programmed cell deathGO:00430691830.014
respiratory gaseous exchangeGO:000758540.014
positive regulation of saliva secretionGO:004687830.014
negative regulation of cellular protein metabolic processGO:00322691060.014
nucleoside phosphate metabolic processGO:00067532830.014
cellular response to mechanical stimulusGO:0071260480.014
monoamine transportGO:0015844430.014
amine transportGO:0015837570.014
negative regulation of cell developmentGO:0010721820.014
long term synaptic potentiationGO:0060291210.014
neurotransmitter gated ion channel clusteringGO:007257830.014
olfactory behaviorGO:004204820.014
response to decreased oxygen levelsGO:00362932370.014
detection of stimulusGO:0051606240.014
cellular response to external stimulusGO:00714961180.014
regulation of phosphorus metabolic processGO:00511743490.014
cellular response to vitamin eGO:007130630.014
regulation of protein processingGO:0070613500.014
positive regulation of nucleic acid templated transcriptionGO:19035081970.014
ribonucleotide biosynthetic processGO:0009260850.013
actin cytoskeleton organizationGO:0030036730.013
positive regulation of response to stimulusGO:00485842850.013
Rat
protein processingGO:0016485680.013
cardiovascular system developmentGO:00723581340.013
regulation of muscle tissue developmentGO:1901861250.013
cellular homeostasisGO:00197252520.013
cholesterol homeostasisGO:004263230.013
regulation of cell growthGO:0001558850.013
positive regulation of humoral immune responseGO:000292220.013
purine containing compound catabolic processGO:00725231380.013
female gonad developmentGO:0008585530.013
neuron neuron synaptic transmissionGO:0007270600.013
nucleoside phosphate biosynthetic processGO:19012931020.013
response to glucoseGO:00097491360.013
positive regulation of neurogenesisGO:00507691650.013

Ppy disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.021
eye and adnexa diseaseDOID:149200.021
nervous system diseaseDOID:86300.021
sensory system diseaseDOID:005015500.021
disease of metabolismDOID:001466700.018