Rattus norvegicus

53 known processes

Pde10a

phosphodiesterase 10A

(Aliases: Pde10a3)

Pde10a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of molecular functionGO:00650093980.163
cellular response to endogenous stimulusGO:00714953770.159
response to oxygen levelsGO:00704822650.153
Rat
cell projection organizationGO:00300303020.131
behaviorGO:00076102050.125
Rat
apoptotic processGO:00069153810.114
Rat
regulation of signal transductionGO:00099663180.107
Mouse
cell cell signalingGO:00072673350.097
protein phosphorylationGO:00064683450.096
regulation of phosphate metabolic processGO:00192203490.092
Rat
regulation of multicellular organismal developmentGO:20000263760.091
neuron projection morphogenesisGO:00488121220.082
anatomical structure morphogenesisGO:00096532980.082
response to inorganic substanceGO:00100353770.080
positive regulation of cell proliferationGO:00082842490.079
regulation of rna metabolic processGO:00512523910.079
cation transportGO:00068123820.077
neuron differentiationGO:00301823680.071
rna biosynthetic processGO:00327743800.070
neuron developmentGO:00486662860.067
metal ion transportGO:00300012890.066
cellular component movementGO:00069282480.065
regulation of catalytic activityGO:00507903040.064
neuron projection developmentGO:00311752730.064
protein complex subunit organizationGO:00718223020.063
regulation of transcription dna templatedGO:00063553740.061
oxoacid metabolic processGO:00434362900.061
response to hypoxiaGO:00016662310.061
Rat
transcription dna templatedGO:00063513770.058
cell motilityGO:00488702020.058
growthGO:00400071650.056
regulation of programmed cell deathGO:00430673410.056
Rat
monovalent inorganic cation transportGO:00156721720.056
regulation of rna biosynthetic processGO:20011413810.055
regulation of phosphorylationGO:00423252480.055
synaptic transmissionGO:00072682350.053
purine nucleoside metabolic processGO:00422781690.052
positive regulation of nervous system developmentGO:00519621780.051
regulation of nervous system developmentGO:00519602640.051
nucleic acid templated transcriptionGO:00976593790.051
positive regulation of multicellular organismal processGO:00512403870.051
Rat
neurological system processGO:00508772190.050
Rat
carbohydrate derivative metabolic processGO:19011353460.050
regulation of cell developmentGO:00602842630.049
positive regulation of phosphorus metabolic processGO:00105622620.049
cellular component biogenesisGO:00440853680.049
response to bacteriumGO:00096172000.048
Rat
synapse organizationGO:0050808460.048
positive regulation of cell developmentGO:00107201760.047
purine ribonucleotide metabolic processGO:00091502270.047
organophosphate metabolic processGO:00196373700.047
nucleoside phosphate metabolic processGO:00067532830.046
regulation of protein metabolic processGO:00512462890.046
cellular amino acid metabolic processGO:00065201070.046
positive regulation of cell differentiationGO:00455972170.045
catabolic processGO:00090563510.045
regulation of protein modification processGO:00313991940.045
cellular component morphogenesisGO:00329891550.045
negative regulation of cell deathGO:00605482290.044
reproductionGO:00000032450.043
macromolecular complex subunit organizationGO:00439333390.043
regulation of neurogenesisGO:00507672470.043
response to peptideGO:19016522920.043
positive regulation of neurogenesisGO:00507691650.042
eye morphogenesisGO:004859240.042
organic acid metabolic processGO:00060822920.041
protein complex biogenesisGO:00702712630.041
negative regulation of signalingGO:00230571570.041
tissue developmentGO:00098882520.041
Rat
multi organism reproductive processGO:00447032620.040
regulation of anatomical structure morphogenesisGO:00226031410.039
purine ribonucleoside metabolic processGO:00461281680.039
protein complex assemblyGO:00064612630.039
regulation of cellular protein metabolic processGO:00322682670.038
single organism catabolic processGO:00447122830.038
organic substance catabolic processGO:19015753160.038
organonitrogen compound biosynthetic processGO:19015661670.038
Rat
brain developmentGO:00074202470.038
transmembrane transportGO:00550854120.038
regulation of synaptic growth at neuromuscular junctionGO:000858210.038
cellular catabolic processGO:00442482950.038
heterocycle catabolic processGO:00467001670.037
carbohydrate derivative catabolic processGO:19011361470.037
regulation of nucleic acid templated transcriptionGO:19035063800.036
regulation of phosphorus metabolic processGO:00511743490.036
Rat
regulation of protein phosphorylationGO:00019321830.036
carboxylic acid metabolic processGO:00197522890.036
ribonucleoside catabolic processGO:00424541260.035
purine ribonucleoside triphosphate metabolic processGO:00092051400.035
regulation of neuron differentiationGO:00456642080.034
cardiac conductionGO:006133720.034
positive regulation of developmental processGO:00510942830.034
cellular ketone metabolic processGO:0042180510.033
purine containing compound catabolic processGO:00725231380.033
negative regulation of multicellular organismal processGO:00512412030.033
intracellular signal transductionGO:00355563140.033
Mouse Rat
regulation of cell proliferationGO:00421273590.032
nucleobase containing small molecule metabolic processGO:00550863160.032
rna metabolic processGO:00160704060.032
nucleoside metabolic processGO:00091161790.032
response to extracellular stimulusGO:00099913800.032
macromolecular complex assemblyGO:00650032730.032
cell communication involved in cardiac conductionGO:008606520.032
response to peptide hormoneGO:00434342780.032
glycosyl compound metabolic processGO:19016571820.031
ribonucleotide metabolic processGO:00092592310.031
sodium ion transportGO:0006814820.031
regulation of angiogenesisGO:0045765390.031
cellular response to peptide hormone stimulusGO:00713751200.031
regulation of cell differentiationGO:00455953200.031
gtp metabolic processGO:0046039720.031
nucleotide metabolic processGO:00091172790.031
positive regulation of rna metabolic processGO:00512542030.031
ribonucleotide catabolic processGO:00092611360.030
localization of cellGO:00516742020.030
cellular component assemblyGO:00226073600.030
positive regulation of signalingGO:00230562700.030
cell morphogenesis involved in differentiationGO:00009041190.030
regulation of dendrite developmentGO:0050773590.030
cellular response to oxygen containing compoundGO:19017013860.030
regulation of apoptotic processGO:00429813350.030
Rat
regulation of neuron projection developmentGO:00109751610.030
ion transmembrane transportGO:00342203650.030
positive regulation of nitrogen compound metabolic processGO:00511733340.030
regulation of system processGO:00440572080.029
Rat
regulation of transferase activityGO:00513381230.029
purine nucleoside triphosphate metabolic processGO:00091441410.029
chemical homeostasisGO:00488782920.029
purine nucleoside triphosphate catabolic processGO:00091461220.029
regulation of cellular amino acid metabolic processGO:000652120.029
biological adhesionGO:00226101100.029
inorganic ion transmembrane transportGO:00986602290.029
negative regulation of apoptotic processGO:00430661810.028
nucleoside triphosphate metabolic processGO:00091411440.028
negative regulation of programmed cell deathGO:00430691830.028
nucleoside triphosphate catabolic processGO:00091431230.028
negative regulation of cell communicationGO:00106481580.028
organonitrogen compound catabolic processGO:19015651790.028
positive regulation of cellular biosynthetic processGO:00313282950.028
purine ribonucleoside catabolic processGO:00461301240.028
purine nucleotide catabolic processGO:00061951360.028
heart contractionGO:0060047570.028
Rat
ribose phosphate metabolic processGO:00196932350.027
ribonucleoside metabolic processGO:00091191740.027
regulation of cellular ketone metabolic processGO:0010565270.027
guanosine containing compound metabolic processGO:1901068740.027
cellular response to nitrogen compoundGO:19016992100.027
response to campGO:0051591910.027
cell growthGO:00160491040.027
ribonucleoside triphosphate metabolic processGO:00091991410.027
divalent metal ion transportGO:00708381320.027
purine nucleoside catabolic processGO:00061521240.027
cell morphogenesis involved in neuron differentiationGO:00486671060.026
cellular response to growth factor stimulusGO:00713631620.026
negative regulation of macromolecule metabolic processGO:00106052600.026
response to nutrientGO:00075842480.026
purine ribonucleoside triphosphate catabolic processGO:00092071220.026
response to estrogenGO:00436272320.026
central nervous system developmentGO:00074173110.025
dendrite developmentGO:0016358720.025
positive regulation of cellular component organizationGO:00511302000.025
positive regulation of gene expressionGO:00106282440.025
angiogenesisGO:0001525530.025
programmed cell deathGO:00125013920.024
Rat
cellular nitrogen compound catabolic processGO:00442701630.024
response to growth factorGO:00708481890.024
positive regulation of cell communicationGO:00106472710.024
response to decreased oxygen levelsGO:00362932370.024
Rat
positive regulation of rna biosynthetic processGO:19026801970.024
cellular response to organonitrogen compoundGO:00714171970.024
regulation of kinase activityGO:00435491170.024
regulation of locomotionGO:00400121480.024
multicellular organismal signalingGO:0035637440.023
response to molecule of bacterial originGO:00022371940.023
Rat
response to metal ionGO:00100382530.023
positive regulation of neuron differentiationGO:00456661260.023
cellular amine metabolic processGO:0044106380.023
organic cyclic compound catabolic processGO:19013611750.023
gtp catabolic processGO:0006184710.023
olfactory learningGO:000835510.023
cellular homeostasisGO:00197252520.023
response to other organismGO:00517072200.023
Rat
sensory perceptionGO:00076001010.022
regulation of transcription from rna polymerase ii promoterGO:00063572340.022
transcription from rna polymerase ii promoterGO:00063662520.022
purine ribonucleotide catabolic processGO:00091541360.022
head developmentGO:00603222470.022
positive regulation of neuron projection developmentGO:0010976990.022
regulation of sodium ion transmembrane transporter activityGO:200064940.021
positive regulation of nucleobase containing compound metabolic processGO:00459353190.021
circulatory system developmentGO:00723591340.021
regulation of growthGO:00400081050.021
regulation of ion transportGO:00432692450.021
response to cytokineGO:00340972150.021
regulation of smooth muscle cell proliferationGO:0048660750.021
regulation of cellular component movementGO:00512701500.021
cellular response to drugGO:0035690300.021
positive regulation of cellular amine metabolic processGO:003324030.021
positive regulation of macromolecule biosynthetic processGO:00105572470.021
calcium ion transportGO:00068161310.020
positive regulation of biosynthetic processGO:00098913190.020
locomotionGO:00400112370.020
response to glucocorticoidGO:00513842230.020
aromatic compound catabolic processGO:00194391680.020
positive regulation of ion transportGO:0043270940.020
ribonucleoside triphosphate catabolic processGO:00092031220.020
multicellular organismal reproductive processGO:00486092330.020
negative regulation of molecular functionGO:00440921330.020
glycosyl compound catabolic processGO:19016581260.020
developmental growthGO:00485891000.020
guanosine containing compound catabolic processGO:1901069710.020
regulation of cellular amine metabolic processGO:003323880.020
secretionGO:00469033070.020
learning or memoryGO:0007611900.020
Rat
response to monosaccharideGO:00342841590.020
negative regulation of developmental processGO:00510931250.020
amine metabolic processGO:0009308380.019
regulation of transmembrane transportGO:00347621220.019
protein oligomerizationGO:00512591910.019
single organism biosynthetic processGO:00447113420.019
Rat
regulation of protein kinase activityGO:00458591050.019
response to estradiolGO:00323551640.019
regulation of blood circulationGO:19035221100.019
Rat
blood vessel morphogenesisGO:0048514580.019
regulation of ion transmembrane transportGO:00347651210.018
memoryGO:0007613540.018
Rat
reproductive processGO:00224143720.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
single organism reproductive processGO:00447022970.018
cellular response to peptideGO:19016531330.018
positive regulation of cellular component movementGO:00512721020.018
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187550.018
positive regulation of transcription dna templatedGO:00458931970.018
embryonic appendage morphogenesisGO:003511340.018
retina morphogenesis in camera type eyeGO:006004210.018
cell projection morphogenesisGO:00488581230.018
regenerationGO:00310991630.018
regulation of secretionGO:00510462240.018
regulation of vasculature developmentGO:1901342440.018
positive regulation of phosphate metabolic processGO:00459372620.017
regulation of calcium ion transportGO:0051924770.017
inorganic cation transmembrane transportGO:00986622020.017
synaptic growth at neuromuscular junctionGO:005112410.017
rhythmic processGO:00485111560.017
vasculature developmentGO:0001944700.017
cellular metal ion homeostasisGO:00068751720.017
positive regulation of nucleic acid templated transcriptionGO:19035081970.017
multicellular organism reproductionGO:00325042330.017
regulation of hydrolase activityGO:00513361430.017
nucleobase containing compound catabolic processGO:00346551520.017
positive regulation of catalytic activityGO:00430851840.017
amide transportGO:00428861050.017
organophosphate catabolic processGO:00464341480.017
wound healingGO:00420601220.017
response to nutrient levelsGO:00316673700.017
nucleotide catabolic processGO:00091661390.017
cation transmembrane transportGO:00986552630.017
response to oxidative stressGO:00069791860.017
cellular lipid metabolic processGO:00442552080.017
negative regulation of protein metabolic processGO:00512481140.017
cellular chemical homeostasisGO:00550822470.016
cognitionGO:0050890920.016
Rat
nucleoside catabolic processGO:00091641260.016
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.016
ion homeostasisGO:00508012120.016
glutamate receptor signaling pathwayGO:0007215430.016
camera type eye morphogenesisGO:004859320.016
response to purine containing compoundGO:00140741260.016
regulation of cellular component organizationGO:00511283680.016
cell morphogenesisGO:00009021420.016
chemosensory behaviorGO:000763520.016
response to external biotic stimulusGO:00432072210.016
Rat
response to hydrogen peroxideGO:0042542890.016
negative regulation of cellular protein metabolic processGO:00322691060.016
homeostatic processGO:00425923310.016
transmission of nerve impulseGO:0019226420.016
response to lipopolysaccharideGO:00324961910.016
Rat
cellular response to stressGO:00335542690.015
divalent inorganic cation homeostasisGO:00725071650.015
ras protein signal transductionGO:0007265290.015
negative regulation of metabolic processGO:00098923310.015
Rat
positive regulation of cell projection organizationGO:00313461110.015
gliogenesisGO:0042063930.015
muscle structure developmentGO:0061061870.015
positive regulation of cardiac muscle cell proliferationGO:006004540.015
cellular divalent inorganic cation homeostasisGO:00725031620.015
regulation of body fluid levelsGO:0050878900.015
action potentialGO:0001508540.015
divalent inorganic cation transportGO:00725111340.015
response to activityGO:0014823730.015
macromolecule localizationGO:00330362520.015
Rat
glucose homeostasisGO:0042593750.014
cell adhesionGO:00071551100.014
central nervous system neuron axonogenesisGO:002195510.014
cell cycleGO:00070491010.014
regulation of cell migrationGO:00303341280.014
cell migrationGO:00164771970.014
sensory organ developmentGO:0007423740.014
positive regulation of molecular functionGO:00440932300.014
small gtpase mediated signal transductionGO:0007264360.014
cardiovascular system developmentGO:00723581340.014
response to amineGO:0014075460.014
sodium ion transmembrane transportGO:0035725670.014
nitrogen compound transportGO:00717052290.014
regulation of intracellular signal transductionGO:19025312180.014
Mouse
axon developmentGO:0061564960.014
regulation of hormone levelsGO:00108171870.014
regulation of cell projection organizationGO:00313441750.014
positive regulation of transportGO:00510502450.013
muscle cell proliferationGO:0033002840.013
regulation of cell motilityGO:20001451310.013
regulation of hormone secretionGO:00468831060.013
neuron deathGO:00709971270.013
neuronal action potentialGO:0019228350.013
cellular macromolecule localizationGO:00707271220.013
Rat
regulation of cellular component biogenesisGO:0044087860.013
positive regulation of cellular protein metabolic processGO:00322701670.013
developmental process involved in reproductionGO:00030061590.013
limb morphogenesisGO:003510840.013
response to corticosteroidGO:00319602350.013
single organism intracellular transportGO:19025821660.013
Rat
regulation of cellular localizationGO:00603412630.013
organic acid biosynthetic processGO:0016053830.013
cell part morphogenesisGO:00329901230.013
cytoskeleton organizationGO:00070101110.013
negative regulation of protein phosphorylationGO:0001933440.013
positive regulation of protein phosphorylationGO:00019341350.013
carbohydrate metabolic processGO:00059751300.013
rho protein signal transductionGO:0007266110.013
negative regulation of nervous system developmentGO:0051961790.013
single organism behaviorGO:00447081300.013
Rat
regulation of homeostatic processGO:00328441010.013
membrane depolarization during cardiac muscle cell action potentialGO:008601210.013
agingGO:00075682410.013
calcium ion homeostasisGO:00550741620.013
embryonic limb morphogenesisGO:003032640.013
positive regulation of smooth muscle cell proliferationGO:0048661510.013
purine nucleotide biosynthetic processGO:0006164830.013
Rat
axis specificationGO:000979840.013
cellular amino acid biosynthetic processGO:0008652320.013
cellular response to external stimulusGO:00714961180.013
gamete generationGO:00072761240.013
organelle organizationGO:00069962660.013
Rat
negative regulation of catalytic activityGO:00430861030.013
negative regulation of biosynthetic processGO:00098901680.012
Rat
positive regulation of intracellular signal transductionGO:19025331380.012
regulation of peptide transportGO:0090087870.012
adult locomotory behaviorGO:000834440.012
spermatogenesisGO:0007283990.012
anatomical structure formation involved in morphogenesisGO:0048646830.012
response to transition metal nanoparticleGO:19902671220.012
positive regulation of locomotionGO:00400171020.012
regulation of synapse assemblyGO:0051963150.012
positive regulation of gtpase activityGO:0043547470.012
positive regulation of signal transductionGO:00099671750.012
organ regenerationGO:00311001010.012
response to ethanolGO:00454711620.012
multicellular organism growthGO:003526410.012
response to glucoseGO:00097491360.012
regulation of gtpase activityGO:0043087570.012
regulation of purine nucleotide catabolic processGO:0033121650.012
positive regulation of protein modification processGO:00314011420.012
regulation of establishment of planar polarityGO:009017520.012
purine nucleotide metabolic processGO:00061632290.012
establishment of tissue polarityGO:000716420.012
regulation of neuron deathGO:19012141150.012
smooth muscle cell proliferationGO:0048659770.012
appendage morphogenesisGO:003510740.012
regulation of synaptic plasticityGO:0048167700.012
negative regulation of protein kinase activityGO:0006469230.011
regulation of insulin secretionGO:0050796650.011
regulation of cell cycleGO:0051726730.011
gastrulationGO:000736920.011
salivary gland morphogenesisGO:000743510.011
respiratory gaseous exchangeGO:000758540.011
response to toxic substanceGO:00096361330.011
adult behaviorGO:0030534160.011
lipid metabolic processGO:00066292830.011
response to woundingGO:00096112540.011
Rat
regulation of catabolic processGO:00098941130.011
cation homeostasisGO:00550801950.011
anion transmembrane transportGO:0098656770.011
negative regulation of phosphorylationGO:0042326570.011
positive regulation of growthGO:0045927550.011
secretion by cellGO:00329402480.011
regulation of synaptic transmissionGO:00508041410.011
reactive nitrogen species metabolic processGO:200105710.011
nucleoside phosphate catabolic processGO:19012921400.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
embryonic pattern specificationGO:000988010.011
alpha amino acid metabolic processGO:1901605710.011
tube developmentGO:0035295890.011
actin filament based movementGO:0030048160.011
cytoplasmic transportGO:00164821150.011
Rat
negative regulation of phosphate metabolic processGO:0045936800.011
Rat
negative regulation of gene expressionGO:00106291990.011
positive regulation of phosphorylationGO:00423271770.011
regulation of small gtpase mediated signal transductionGO:0051056480.011
sexual reproductionGO:00199531480.011
feeding behaviorGO:0007631530.011
protein transportGO:00150311320.011
Rat
insulin like growth factor receptor signaling pathwayGO:004800930.011
reproductive system developmentGO:00614581280.010
male gamete generationGO:0048232990.010
negative regulation of nitrogen compound metabolic processGO:00511721610.010
Rat
cellular response to oxygen levelsGO:0071453600.010
response to light stimulusGO:0009416520.010
reactive oxygen species biosynthetic processGO:190340980.010
proteolysisGO:00065081750.010
regulation of nucleoside metabolic processGO:0009118660.010
blood circulationGO:00080151830.010
Rat
blood vessel developmentGO:0001568690.010
dendrite morphogenesisGO:0048813430.010
muscle tissue developmentGO:0060537580.010
response to organophosphorusGO:00466831020.010
axonogenesisGO:0007409710.010
positive regulation of kinase activityGO:0033674770.010
response to acid chemicalGO:00011012220.010

Pde10a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
nervous system diseaseDOID:86300.016
myopathyDOID:42300.010
muscle tissue diseaseDOID:6600.010
musculoskeletal system diseaseDOID:1700.010
muscular diseaseDOID:008000000.010