Rattus norvegicus

17 known processes

Defb1

defensin beta 1

Defb1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
monovalent inorganic cation transportGO:00156721720.504
reproductive processGO:00224143720.353
transcription from rna polymerase ii promoterGO:00063662520.350
cation transmembrane transportGO:00986552630.323
cellular component morphogenesisGO:00329891550.239
regulation of transcription dna templatedGO:00063553740.191
transmembrane transportGO:00550854120.186
nitrogen compound transportGO:00717052290.170
regulation of secretionGO:00510462240.164
negative regulation of transcription dna templatedGO:00458921160.163
circulatory system developmentGO:00723591340.161
cell cell signalingGO:00072673350.156
response to nutrient levelsGO:00316673700.154
regulation of rna metabolic processGO:00512523910.150
inorganic cation transmembrane transportGO:00986622020.143
positive regulation of apoptotic processGO:00430651540.142
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.137
positive regulation of phosphorus metabolic processGO:00105622620.134
rna biosynthetic processGO:00327743800.132
positive regulation of biosynthetic processGO:00098913190.130
positive regulation of cell deathGO:00109421840.130
positive regulation of cellular biosynthetic processGO:00313282950.129
nucleic acid templated transcriptionGO:00976593790.129
regulation of transcription from rna polymerase ii promoterGO:00063572340.128
cellular response to endogenous stimulusGO:00714953770.126
rna metabolic processGO:00160704060.126
cellular component movementGO:00069282480.123
regulation of rna biosynthetic processGO:20011413810.122
cellular response to lipidGO:00713962010.120
response to molecule of bacterial originGO:00022371940.115
intracellular signal transductionGO:00355563140.114
negative regulation of nucleobase containing compound metabolic processGO:00459341530.113
regulation of neuron differentiationGO:00456642080.108
response to acid chemicalGO:00011012220.107
response to peptide hormoneGO:00434342780.105
regulation of multicellular organismal developmentGO:20000263760.103
negative regulation of macromolecule biosynthetic processGO:00105581480.101
response to estradiolGO:00323551640.101
organic acid transportGO:00158491160.098
cation transportGO:00068123820.097
negative regulation of nitrogen compound metabolic processGO:00511721610.095
regulation of cell proliferationGO:00421273590.095
positive regulation of rna biosynthetic processGO:19026801970.095
multi organism reproductive processGO:00447032620.094
negative regulation of rna biosynthetic processGO:19026791180.093
transcription dna templatedGO:00063513770.091
negative regulation of nucleic acid templated transcriptionGO:19035071170.090
single organism reproductive processGO:00447022970.089
regulation of cell migrationGO:00303341280.088
positive regulation of phosphate metabolic processGO:00459372620.088
regulation of nervous system developmentGO:00519602640.087
cellular response to organic cyclic compoundGO:00714072020.083
positive regulation of cellular protein metabolic processGO:00322701670.082
negative regulation of gene expressionGO:00106291990.082
regulation of catalytic activityGO:00507903040.080
epithelium developmentGO:0060429960.080
regulation of molecular functionGO:00650093980.079
neuron projection morphogenesisGO:00488121220.078
response to nutrientGO:00075842480.078
cell projection organizationGO:00300303020.078
apoptotic processGO:00069153810.078
negative regulation of rna metabolic processGO:00512531230.077
cellular response to hormone stimulusGO:00328702470.076
response to carbohydrateGO:00097431830.076
inorganic ion transmembrane transportGO:00986602290.073
regulation of cellular ketone metabolic processGO:0010565270.073
taxisGO:0042330670.071
negative regulation of cellular biosynthetic processGO:00313271610.071
regulation of cellular protein metabolic processGO:00322682670.071
response to monosaccharideGO:00342841590.070
cell projection morphogenesisGO:00488581230.070
cell morphogenesisGO:00009021420.070
positive regulation of molecular functionGO:00440932300.070
positive regulation of nucleic acid templated transcriptionGO:19035081970.069
positive regulation of multicellular organismal processGO:00512403870.069
response to peptideGO:19016522920.069
response to extracellular stimulusGO:00099913800.068
cellular response to oxygen containing compoundGO:19017013860.068
programmed cell deathGO:00125013920.068
regulation of response to stressGO:00801341260.067
negative regulation of biosynthetic processGO:00098901680.067
regulation of ion transportGO:00432692450.067
response to hypoxiaGO:00016662310.067
regulation of programmed cell deathGO:00430673410.066
negative regulation of macromolecule metabolic processGO:00106052600.066
regulation of apoptotic processGO:00429813350.066
locomotionGO:00400112370.065
regulation of cell projection organizationGO:00313441750.065
positive regulation of response to stimulusGO:00485842850.065
regulation of phosphorylationGO:00423252480.064
organic anion transportGO:00157111320.064
regulation of lipid biosynthetic processGO:0046890380.063
positive regulation of nitrogen compound metabolic processGO:00511733340.063
regulation of locomotionGO:00400121480.062
sodium ion transmembrane transportGO:0035725670.062
positive regulation of developmental processGO:00510942830.062
reproductionGO:00000032450.062
response to other organismGO:00517072200.062
cell motilityGO:00488702020.061
catabolic processGO:00090563510.061
positive regulation of gene expressionGO:00106282440.060
regulation of neurogenesisGO:00507672470.060
response to cytokineGO:00340972150.060
response to oxygen levelsGO:00704822650.059
cell part morphogenesisGO:00329901230.057
negative regulation of transportGO:00510511360.056
brain developmentGO:00074202470.056
ion transmembrane transportGO:00342203650.055
organophosphate metabolic processGO:00196373700.055
sex differentiationGO:00075481130.055
response to biotic stimulusGO:00096072260.054
response to inorganic substanceGO:00100353770.054
positive regulation of catalytic activityGO:00430851840.053
regulation of phosphorus metabolic processGO:00511743490.053
neuron differentiationGO:00301823680.051
positive regulation of protein metabolic processGO:00512471780.050
positive regulation of signalingGO:00230562700.050
positive regulation of programmed cell deathGO:00430681570.050
female pregnancyGO:00075651220.049
cellular response to acid chemicalGO:0071229750.049
metal ion transportGO:00300012890.049
enzyme linked receptor protein signaling pathwayGO:00071671160.049
response to external biotic stimulusGO:00432072210.048
regulation of hormone levelsGO:00108171870.048
oxoacid metabolic processGO:00434362900.048
neuron developmentGO:00486662860.048
central nervous system developmentGO:00074173110.048
multicellular organismal reproductive processGO:00486092330.048
positive regulation of rna metabolic processGO:00512542030.048
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.048
secretionGO:00469033070.047
homeostatic processGO:00425923310.047
regulation of cell differentiationGO:00455953200.046
regulation of phosphate metabolic processGO:00192203490.046
regulation of cell developmentGO:00602842630.046
regulation of signal transductionGO:00099663180.046
cellular lipid metabolic processGO:00442552080.046
cardiovascular system developmentGO:00723581340.045
multicellular organism reproductionGO:00325042330.045
bmp signaling pathwayGO:003050940.044
tube developmentGO:0035295890.044
heart developmentGO:0007507720.044
positive regulation of transcription dna templatedGO:00458931970.043
response to estrogenGO:00436272320.043
localization of cellGO:00516742020.043
peptide transportGO:0015833970.042
negative regulation of signalingGO:00230571570.042
nucleotide catabolic processGO:00091661390.042
nucleobase containing small molecule metabolic processGO:00550863160.042
negative regulation of cell deathGO:00605482290.042
positive regulation of cell proliferationGO:00082842490.041
carboxylic acid metabolic processGO:00197522890.041
regulation of anatomical structure sizeGO:00900661350.041
embryo implantationGO:0007566150.041
negative regulation of cellular metabolic processGO:00313242810.041
protein homooligomerizationGO:0051260910.040
lipid biosynthetic processGO:00086101280.040
single organism catabolic processGO:00447122830.040
response to decreased oxygen levelsGO:00362932370.040
negative regulation of metabolic processGO:00098923310.040
response to metal ionGO:00100382530.039
cellular response to external stimulusGO:00714961180.039
sodium ion transportGO:0006814820.039
tissue developmentGO:00098882520.039
cellular response to abiotic stimulusGO:0071214850.039
positive regulation of cell differentiationGO:00455972170.039
head developmentGO:00603222470.039
agingGO:00075682410.038
organic substance catabolic processGO:19015753160.038
positive regulation of cell developmentGO:00107201760.038
negative regulation of collagen biosynthetic processGO:003296640.038
anatomical structure morphogenesisGO:00096532980.037
regulation of neuron projection developmentGO:00109751610.037
development of primary female sexual characteristicsGO:0046545560.037
protein complex biogenesisGO:00702712630.037
gonad developmentGO:00084061040.037
regulation of protein metabolic processGO:00512462890.036
cell morphogenesis involved in neuron differentiationGO:00486671060.036
circulatory system processGO:00030131830.036
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.036
protein phosphorylationGO:00064683450.035
negative regulation of developmental processGO:00510931250.035
positive regulation of macromolecule biosynthetic processGO:00105572470.035
ovulation cycleGO:0042698670.035
anion transportGO:00068201780.034
anatomical structure formation involved in morphogenesisGO:0048646830.034
anion transmembrane transportGO:0098656770.033
regulation of lipid metabolic processGO:0019216680.033
response to woundingGO:00096112540.033
regulation of intracellular signal transductionGO:19025312180.033
response to organophosphorusGO:00466831020.032
amide transportGO:00428861050.032
cellular component biogenesisGO:00440853680.032
multi multicellular organism processGO:00447061380.031
cellular component assemblyGO:00226073600.031
positive regulation of phosphorylationGO:00423271770.031
regulation of blood pressureGO:0008217830.031
response to hexoseGO:00097461440.031
epithelial cell proliferationGO:0050673540.031
monocarboxylic acid transportGO:0015718520.030
female gonad developmentGO:0008585530.030
leukocyte cell cell adhesionGO:000715940.030
regulation of cellular localizationGO:00603412630.030
response to retinoic acidGO:0032526630.030
negative regulation of cell developmentGO:0010721820.030
muscle structure developmentGO:0061061870.030
negative regulation of multicellular organismal processGO:00512412030.029
steroid biosynthetic processGO:0006694480.029
epithelial cell differentiationGO:0030855710.029
regulation of protein modification processGO:00313991940.029
hormone secretionGO:00468791150.029
positive regulation of cell communicationGO:00106472710.029
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
amine metabolic processGO:0009308380.028
single organism biosynthetic processGO:00447113420.028
regulation of cellular component organizationGO:00511283680.028
cytokine mediated signaling pathwayGO:0019221430.028
nucleoside phosphate metabolic processGO:00067532830.028
regulation of phagocytosis engulfmentGO:006009940.028
renal system developmentGO:0072001670.027
carbohydrate derivative metabolic processGO:19011353460.027
neuron projection developmentGO:00311752730.027
cellular response to stressGO:00335542690.027
positive regulation of signal transductionGO:00099671750.027
regulation of anatomical structure morphogenesisGO:00226031410.027
response to bacteriumGO:00096172000.027
positive regulation of phagocytosis engulfmentGO:006010040.026
defense responseGO:00069521940.026
chemical homeostasisGO:00488782920.026
positive regulation of protein modification processGO:00314011420.026
growthGO:00400071650.026
positive regulation of nervous system developmentGO:00519621780.026
response to purine containing compoundGO:00140741260.025
nucleotide metabolic processGO:00091172790.025
regulation of membrane potentialGO:00423911100.025
regulation of sodium ion transmembrane transporter activityGO:200064940.025
negative regulation of molecular functionGO:00440921330.025
positive regulation of neurogenesisGO:00507691650.025
positive regulation of cell projection organizationGO:00313461110.025
response to growth factorGO:00708481890.025
regulation of kinase activityGO:00435491170.025
cellular amine metabolic processGO:0044106380.024
regulation of system processGO:00440572080.024
blood circulationGO:00080151830.024
negative regulation of cell differentiationGO:0045596990.024
vitamin transportGO:0051180140.024
regulation of protein phosphorylationGO:00019321830.024
regulation of neuron deathGO:19012141150.023
reproductive system developmentGO:00614581280.023
neuron deathGO:00709971270.023
regulation of hormone secretionGO:00468831060.023
regulation of fat cell differentiationGO:004559830.023
chemotaxisGO:0006935660.023
regulation of catabolic processGO:00098941130.023
negative regulation of heart growthGO:006111730.023
anterior posterior pattern specificationGO:000995210.023
regulation of nucleic acid templated transcriptionGO:19035063800.023
positive regulation of protein phosphorylationGO:00019341350.023
cellular response to steroid hormone stimulusGO:0071383930.022
regulation of cellular amine metabolic processGO:003323880.022
positive regulation of intracellular signal transductionGO:19025331380.022
ovulation cycle processGO:0022602500.022
peptide hormone secretionGO:0030072840.022
response to glucoseGO:00097491360.022
protein complex assemblyGO:00064612630.022
potassium ion transportGO:0006813970.022
monocarboxylic acid metabolic processGO:00327871520.022
cell morphogenesis involved in differentiationGO:00009041190.022
cellular response to gonadotropin stimulusGO:0071371170.022
peptide secretionGO:0002790860.022
cellular ketone metabolic processGO:0042180510.022
steroid metabolic processGO:0008202730.022
g protein coupled receptor internalizationGO:000203130.022
ribose phosphate metabolic processGO:00196932350.021
vascular process in circulatory systemGO:0003018960.021
cell adhesionGO:00071551100.021
macromolecular complex assemblyGO:00650032730.021
proteolysisGO:00065081750.021
regulation of cellular amino acid metabolic processGO:000652120.021
signal releaseGO:00230611450.021
negative regulation of cell proliferationGO:00082851190.021
positive regulation of cell motilityGO:2000147970.021
multicellular organismal signalingGO:0035637440.021
urogenital system developmentGO:0001655780.021
response to lipopolysaccharideGO:00324961910.021
female sex differentiationGO:0046660590.021
hormone transportGO:00099141210.021
organic acid metabolic processGO:00060822920.021
metal ion homeostasisGO:00550651860.021
negative regulation of neuron differentiationGO:0045665620.020
lipid oxidationGO:0034440300.020
protein oligomerizationGO:00512591910.020
positive regulation of neuron projection developmentGO:0010976990.020
axis specificationGO:000979840.020
biological adhesionGO:00226101100.020
cellular metal ion homeostasisGO:00068751720.020
positive regulation of epithelial cell proliferationGO:0050679320.020
cellular response to cytokine stimulusGO:00713451270.020
divalent inorganic cation transportGO:00725111340.020
negative regulation of secretionGO:0051048820.020
hormone biosynthetic processGO:0042446250.019
lipid metabolic processGO:00066292830.019
multicellular organismal response to stressGO:0033555250.019
reactive oxygen species metabolic processGO:0072593370.019
response to insulinGO:00328681330.019
organophosphate biosynthetic processGO:00904071430.019
positive regulation of cellular amino acid metabolic processGO:004576410.019
cytokine productionGO:0001816610.019
erythrocyte differentiationGO:003021810.019
response to interleukin 1GO:0070555550.019
muscle cell proliferationGO:0033002840.019
secretion by cellGO:00329402480.019
regulation of cellular component movementGO:00512701500.018
prostaglandin transportGO:001573280.018
regulation of cytokine productionGO:0001817560.018
nucleoside phosphate catabolic processGO:19012921400.018
ion homeostasisGO:00508012120.018
positive regulation of cellular component movementGO:00512721020.018
neuron apoptotic processGO:0051402880.018
regulation of secretion by cellGO:19035302080.018
regulation of organic acid transportGO:0032890350.018
protein complex subunit organizationGO:00718223020.018
cell type specific apoptotic processGO:00972851340.018
negative regulation of secretion by cellGO:1903531720.018
cellular response to oxygen levelsGO:0071453600.018
regulation of growthGO:00400081050.018
sulfur compound transportGO:007234880.017
regulation of behaviorGO:0050795610.017
action potentialGO:0001508540.017
regulation of cell motilityGO:20001451310.017
heart morphogenesisGO:000300730.017
jak stat cascadeGO:0007259260.017
ribonucleotide metabolic processGO:00092592310.017
response to tumor necrosis factorGO:0034612560.017
purine nucleotide metabolic processGO:00061632290.017
negative regulation of ion transportGO:0043271510.017
organic hydroxy compound transportGO:0015850770.017
male sex differentiationGO:0046661640.017
rhythmic processGO:00485111560.017
behaviorGO:00076102050.017
negative regulation of cell communicationGO:00106481580.017
nucleobase containing compound catabolic processGO:00346551520.016
positive regulation of ion transportGO:0043270940.016
reproductive structure developmentGO:00486081280.016
vitamin d receptor signaling pathwayGO:007056110.016
purine containing compound metabolic processGO:00725212530.016
ribonucleoside metabolic processGO:00091191740.016
single organism cell adhesionGO:0098602460.016
axonogenesisGO:0007409710.016
small molecule biosynthetic processGO:00442831240.016
macromolecular complex subunit organizationGO:00439333390.016
regulation of blood circulationGO:19035221100.016
response to glucocorticoidGO:00513842230.016
negative regulation of signal transductionGO:0009968830.016
cellular response to lipopolysaccharideGO:0071222550.016
negative regulation of response to stimulusGO:00485851550.016
ribonucleoside catabolic processGO:00424541260.015
unsaturated fatty acid metabolic processGO:0033559390.015
diterpenoid metabolic processGO:0016101330.015
regulation of blood vessel sizeGO:0050880890.015
cellular response to organonitrogen compoundGO:00714171970.015
cellular response to alcoholGO:0097306870.015
alcohol metabolic processGO:0006066770.015
multicellular organismal homeostasisGO:0048871490.015
cellular homeostasisGO:00197252520.015
oxidation reduction processGO:00551143040.015
glycosyl compound metabolic processGO:19016571820.015
negative regulation of apoptotic processGO:00430661810.015
aromatic compound catabolic processGO:00194391680.015
ras protein signal transductionGO:0007265290.015
reactive nitrogen species metabolic processGO:200105710.015
positive regulation of lipid metabolic processGO:0045834330.015
modified amino acid transportGO:0072337120.015
behavioral response to nicotineGO:003509520.015
heart contractionGO:0060047570.015
mesoderm developmentGO:000749820.015
carbohydrate derivative catabolic processGO:19011361470.015
regulation of protein localizationGO:0032880810.015
regulation of transcription regulatory region dna bindingGO:200067740.015
carboxylic acid transportGO:00469421150.015
response to mechanical stimulusGO:00096121340.014
negative regulation of cardiac muscle tissue developmentGO:005502630.014
tissue regenerationGO:0042246360.014
embryo developmentGO:0009790490.014
cell communication involved in cardiac conductionGO:008606520.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092100.014
developmental process involved in reproductionGO:00030061590.014
ovarian follicle developmentGO:0001541310.014
response to progesteroneGO:0032570480.014
carboxylic acid biosynthetic processGO:0046394830.014
endocrine system developmentGO:0035270300.014
negative regulation of nervous system developmentGO:0051961790.014
small gtpase mediated signal transductionGO:0007264360.014
amino acid transportGO:0006865700.014
regulation of reactive oxygen species metabolic processGO:2000377260.014
cellular response to growth factor stimulusGO:00713631620.014
regulation of peptide hormone secretionGO:0090276800.014
regulation of interleukin 6 productionGO:0032675120.014
negative regulation of cardiac muscle tissue growthGO:005502230.014
regulation of hydrolase activityGO:00513361430.014
response to calcium ionGO:0051592590.014
organonitrogen compound catabolic processGO:19015651790.013
embryonic skeletal system developmentGO:004870630.013
cell migrationGO:00164771970.013
protein ubiquitinationGO:0016567280.013
mapk cascadeGO:00001651400.013
response to vitaminGO:00332731310.013
sexual reproductionGO:00199531480.013
negative regulation of neuron deathGO:1901215690.013
hormone metabolic processGO:0042445690.013
regulation of muscle contractionGO:0006937530.013
digestive tract developmentGO:0048565390.013
embryonic axis specificationGO:000057810.013
protein modification by small protein conjugation or removalGO:0070647350.013
negative regulation of pancreatic stellate cell proliferationGO:200023010.013
neurological system processGO:00508772190.013
macromolecule localizationGO:00330362520.013
negative regulation of neurogenesisGO:0050768780.013
immune system processGO:00023762040.013
development of primary sexual characteristicsGO:00451371070.013
organonitrogen compound biosynthetic processGO:19015661670.013
regulation of insulin secretionGO:0050796650.013
regulation of smooth muscle cell proliferationGO:0048660750.013
regulation of protein kinase activityGO:00458591050.013
regulation of muscle tissue developmentGO:1901861250.013
multicellular organismal water homeostasisGO:005089140.013
developmental growthGO:00485891000.013
cardiac ventricle developmentGO:000323110.013
cellular potassium ion transportGO:0071804720.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.013
positive regulation of lipid biosynthetic processGO:0046889250.012
regulation of epithelial cell differentiationGO:0030856120.012
response to fatty acidGO:0070542650.012
gastrulationGO:000736920.012
respiratory tube developmentGO:0030323430.012
response to transforming growth factor betaGO:0071559460.012
muscle organ developmentGO:0007517500.012
embryonic skeletal system morphogenesisGO:004870430.012
vitamin a metabolic processGO:000677620.012
heart processGO:0003015570.012
cellular macromolecular complex assemblyGO:0034622580.012
regulation of metal ion transportGO:00109591180.012
single organism carbohydrate metabolic processGO:00447231180.012
response to amino acidGO:0043200750.012
cellular response to tumor necrosis factorGO:0071356460.012
response to toxic substanceGO:00096361330.012
positive regulation of cellular amine metabolic processGO:003324030.012
vesicle mediated transportGO:00161921810.012
regulation of organ formationGO:000315620.012
cellular catabolic processGO:00442482950.012
lymphocyte activation involved in immune responseGO:000228530.012
lipid transportGO:0006869610.011
interferon gamma productionGO:003260930.011
striated muscle tissue developmentGO:0014706580.011
cardiac muscle cell proliferationGO:006003860.011
potassium ion transmembrane transportGO:0071805710.011
isoprenoid metabolic processGO:0006720450.011
cardiac chamber developmentGO:000320510.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
g protein coupled receptor signaling pathwayGO:00071862420.011
lipid modificationGO:0030258520.011
positive regulation of catabolic processGO:0009896780.011
fatty acid oxidationGO:0019395290.011
positive regulation of cellular component organizationGO:00511302000.011
amino acid transmembrane transportGO:0003333330.011
multicellular organism growthGO:003526410.011
protein modification by small protein conjugationGO:0032446310.011
neural crest cell developmentGO:001403220.011
tissue morphogenesisGO:0048729220.011
calcium ion homeostasisGO:00550741620.011
gliogenesisGO:0042063930.011
lipid storageGO:001991510.011
regulation of developmental growthGO:0048638450.011
l glutamate importGO:005193820.011
divalent inorganic cation homeostasisGO:00725071650.011
single organism behaviorGO:00447081300.011
small molecule catabolic processGO:0044282590.011
smooth muscle cell proliferationGO:0048659770.011
neurotransmitter uptakeGO:000150430.011
cell growthGO:00160491040.011
monocarboxylic acid biosynthetic processGO:0072330480.011
response to gonadotropinGO:0034698340.011
regulation of homeostatic processGO:00328441010.011
skin developmentGO:0043588170.011
positive regulation of transportGO:00510502450.011

Defb1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.093
disease of anatomical entityDOID:700.093
kidney diseaseDOID:55700.093
obesityDOID:997000.025
acquired metabolic diseaseDOID:006015800.025
overnutritionDOID:65400.025
nutrition diseaseDOID:37400.025
disease of metabolismDOID:001466700.025
nervous system diseaseDOID:86300.025