Rattus norvegicus

52 known processes

Pi4k2a

phosphatidylinositol 4-kinase type 2 alpha

(Aliases: Pi4KII)

Pi4k2a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of transcription dna templatedGO:00063553740.185
neuron differentiationGO:00301823680.166
anatomical structure morphogenesisGO:00096532980.148
cellular response to oxygen containing compoundGO:19017013860.124
transcription dna templatedGO:00063513770.111
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.109
regulation of transcription from rna polymerase ii promoterGO:00063572340.102
negative regulation of metabolic processGO:00098923310.094
negative regulation of macromolecule metabolic processGO:00106052600.093
regulation of molecular functionGO:00650093980.090
response to metal ionGO:00100382530.090
rna metabolic processGO:00160704060.089
response to inorganic substanceGO:00100353770.081
positive regulation of nucleic acid templated transcriptionGO:19035081970.080
regulation of nucleic acid templated transcriptionGO:19035063800.078
regulation of protein metabolic processGO:00512462890.074
transcription from rna polymerase ii promoterGO:00063662520.074
regulation of rna biosynthetic processGO:20011413810.072
negative regulation of gene expressionGO:00106291990.072
cellular response to nitrogen compoundGO:19016992100.069
response to lipopolysaccharideGO:00324961910.067
cellular response to oxidative stressGO:0034599760.066
response to purine containing compoundGO:00140741260.065
rna biosynthetic processGO:00327743800.065
regulation of cellular component organizationGO:00511283680.064
negative regulation of macromolecule biosynthetic processGO:00105581480.063
regulation of cell developmentGO:00602842630.063
response to cytokineGO:00340972150.061
negative regulation of transcription dna templatedGO:00458921160.061
response to extracellular stimulusGO:00099913800.060
cellular response to endogenous stimulusGO:00714953770.060
cellular response to stressGO:00335542690.059
nucleic acid templated transcriptionGO:00976593790.059
intracellular signal transductionGO:00355563140.058
macromolecular complex assemblyGO:00650032730.058
regulation of phosphate metabolic processGO:00192203490.057
regulation of rna metabolic processGO:00512523910.055
positive regulation of nitrogen compound metabolic processGO:00511733340.054
positive regulation of nucleobase containing compound metabolic processGO:00459353190.054
regulation of phosphorus metabolic processGO:00511743490.053
regulation of signal transductionGO:00099663180.052
negative regulation of cell deathGO:00605482290.051
response to biotic stimulusGO:00096072260.051
positive regulation of catalytic activityGO:00430851840.050
regulation of neuron deathGO:19012141150.050
cellular chemical homeostasisGO:00550822470.049
cellular response to cytokine stimulusGO:00713451270.049
response to molecule of bacterial originGO:00022371940.049
cellular response to biotic stimulusGO:0071216590.048
neuron projection developmentGO:00311752730.048
regulation of nervous system developmentGO:00519602640.047
negative regulation of rna metabolic processGO:00512531230.047
neurological system processGO:00508772190.047
cell projection organizationGO:00300303020.046
reproductionGO:00000032450.046
negative regulation of cellular metabolic processGO:00313242810.046
negative regulation of cellular biosynthetic processGO:00313271610.045
multi organism reproductive processGO:00447032620.044
neuron developmentGO:00486662860.044
negative regulation of nucleobase containing compound metabolic processGO:00459341530.043
muscle system processGO:00030121150.043
macromolecular complex subunit organizationGO:00439333390.043
regulation of cellular protein metabolic processGO:00322682670.042
organelle organizationGO:00069962660.042
positive regulation of transcription dna templatedGO:00458931970.042
positive regulation of biosynthetic processGO:00098913190.042
single organism reproductive processGO:00447022970.042
neuron apoptotic processGO:0051402880.041
response to other organismGO:00517072200.041
positive regulation of phosphorus metabolic processGO:00105622620.041
cellular homeostasisGO:00197252520.040
positive regulation of gene expressionGO:00106282440.040
single organism intracellular transportGO:19025821660.040
cellular cation homeostasisGO:00300031800.040
regulation of membrane potentialGO:00423911100.039
cellular response to organic cyclic compoundGO:00714072020.039
response to peptideGO:19016522920.039
cell morphogenesis involved in neuron differentiationGO:00486671060.038
chemical homeostasisGO:00488782920.038
regulation of catalytic activityGO:00507903040.038
negative regulation of nitrogen compound metabolic processGO:00511721610.038
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.037
negative regulation of neuron deathGO:1901215690.037
negative regulation of rna biosynthetic processGO:19026791180.036
neuron deathGO:00709971270.036
positive regulation of transportGO:00510502450.036
positive regulation of cellular biosynthetic processGO:00313282950.036
macromolecule localizationGO:00330362520.036
cell part morphogenesisGO:00329901230.035
ion homeostasisGO:00508012120.035
response to decreased oxygen levelsGO:00362932370.035
cellular component movementGO:00069282480.034
negative regulation of apoptotic processGO:00430661810.034
cellular response to reactive oxygen speciesGO:0034614550.034
positive regulation of macromolecule biosynthetic processGO:00105572470.034
cellular response to peptide hormone stimulusGO:00713751200.034
negative regulation of biosynthetic processGO:00098901680.034
cell morphogenesisGO:00009021420.034
response to external biotic stimulusGO:00432072210.034
response to radiationGO:00093141370.033
cellular response to hormone stimulusGO:00328702470.033
cellular ion homeostasisGO:00068731840.033
response to campGO:0051591910.033
response to bacteriumGO:00096172000.033
positive regulation of nervous system developmentGO:00519621780.033
regulation of cell differentiationGO:00455953200.033
regulation of lipid metabolic processGO:0019216680.033
positive regulation of phosphate metabolic processGO:00459372620.033
reproductive processGO:00224143720.032
cation homeostasisGO:00550801950.032
cellular response to organonitrogen compoundGO:00714171970.032
cellular response to external stimulusGO:00714961180.032
negative regulation of programmed cell deathGO:00430691830.031
behaviorGO:00076102050.031
cellular component biogenesisGO:00440853680.030
cellular response to lipidGO:00713962010.030
response to nutrient levelsGO:00316673700.030
negative regulation of signalingGO:00230571570.029
response to insulinGO:00328681330.029
response to oxidative stressGO:00069791860.029
protein complex subunit organizationGO:00718223020.029
cell morphogenesis involved in differentiationGO:00009041190.029
inorganic ion transmembrane transportGO:00986602290.029
regulation of intracellular signal transductionGO:19025312180.029
protein complex biogenesisGO:00702712630.028
potassium ion transportGO:0006813970.028
single organism cellular localizationGO:19025801020.028
positive regulation of nucleoside metabolic processGO:0045979550.028
agingGO:00075682410.027
response to acid chemicalGO:00011012220.027
multicellular organismal reproductive processGO:00486092330.027
regulation of programmed cell deathGO:00430673410.026
cellular divalent inorganic cation homeostasisGO:00725031620.026
metal ion homeostasisGO:00550651860.026
regulation of system processGO:00440572080.026
regulation of catabolic processGO:00098941130.026
positive regulation of rna biosynthetic processGO:19026801970.026
negative regulation of response to stimulusGO:00485851550.026
cellular component morphogenesisGO:00329891550.026
cellular amino acid metabolic processGO:00065201070.026
locomotionGO:00400112370.026
tube developmentGO:0035295890.025
cellular response to peptideGO:19016531330.025
negative regulation of nucleic acid templated transcriptionGO:19035071170.025
regulation of apoptotic processGO:00429813350.024
regulation of cellular ketone metabolic processGO:0010565270.024
regulation of neuron differentiationGO:00456642080.024
circadian rhythmGO:0007623880.024
oxoacid metabolic processGO:00434362900.024
cell projection morphogenesisGO:00488581230.024
protein complex assemblyGO:00064612630.024
anion transportGO:00068201780.024
transmembrane transportGO:00550854120.024
response to peptide hormoneGO:00434342780.023
positive regulation of neurogenesisGO:00507691650.023
reproductive structure developmentGO:00486081280.023
positive regulation of molecular functionGO:00440932300.023
muscle contractionGO:0006936880.023
purine ribonucleoside triphosphate metabolic processGO:00092051400.023
purine nucleotide metabolic processGO:00061632290.022
ion transmembrane transportGO:00342203650.022
negative regulation of signal transductionGO:0009968830.022
cellular ketone metabolic processGO:0042180510.021
organ morphogenesisGO:0009887750.021
cellular response to molecule of bacterial originGO:0071219560.021
lipid metabolic processGO:00066292830.021
vesicle mediated transportGO:00161921810.021
response to estrogenGO:00436272320.021
synaptic transmissionGO:00072682350.020
positive regulation of developmental processGO:00510942830.020
organophosphate metabolic processGO:00196373700.020
regulation of neuron projection developmentGO:00109751610.020
negative regulation of cell communicationGO:00106481580.020
nucleoside phosphate metabolic processGO:00067532830.020
catabolic processGO:00090563510.020
positive regulation of cell proliferationGO:00082842490.020
regulation of homeostatic processGO:00328441010.019
regulation of hydrolase activityGO:00513361430.019
sexual reproductionGO:00199531480.019
response to estradiolGO:00323551640.019
cell type specific apoptotic processGO:00972851340.019
purine ribonucleotide metabolic processGO:00091502270.019
rhythmic processGO:00485111560.019
learning or memoryGO:0007611900.019
cellular component assemblyGO:00226073600.019
multi multicellular organism processGO:00447061380.019
response to mechanical stimulusGO:00096121340.019
response to growth factorGO:00708481890.019
regulation of cellular amino acid metabolic processGO:000652120.018
monovalent inorganic cation transportGO:00156721720.018
metal ion transportGO:00300012890.018
ribose phosphate metabolic processGO:00196932350.018
positive regulation of hydrolase activityGO:0051345860.018
positive regulation of catabolic processGO:0009896780.018
regulation of multicellular organismal developmentGO:20000263760.018
regulation of cell proliferationGO:00421273590.018
cellular protein localizationGO:00346131220.018
cellular response to nitriteGO:007125020.018
response to hypoxiaGO:00016662310.018
multicellular organism reproductionGO:00325042330.018
cellular response to lipopolysaccharideGO:0071222550.017
membrane organizationGO:0061024940.017
carboxylic acid metabolic processGO:00197522890.017
regulation of hormone levelsGO:00108171870.017
regulation of secretion by cellGO:19035302080.017
cardiovascular system developmentGO:00723581340.017
organelle localizationGO:0051640550.017
regulation of phosphorylationGO:00423252480.017
single organism biosynthetic processGO:00447113420.017
dna metabolic processGO:0006259960.017
sensory perceptionGO:00076001010.017
cell cell signalingGO:00072673350.017
vascular process in circulatory systemGO:0003018960.017
cellular amine metabolic processGO:0044106380.017
positive regulation of cell differentiationGO:00455972170.017
positive regulation of protein modification processGO:00314011420.017
tissue developmentGO:00098882520.016
single organism organelle organizationGO:19025891800.016
response to carbohydrateGO:00097431830.016
response to toxic substanceGO:00096361330.016
proteolysisGO:00065081750.016
regulation of transmembrane transportGO:00347621220.016
regulation of cellular amine metabolic processGO:003323880.016
response to alkaloidGO:00432791320.016
single organism catabolic processGO:00447122830.016
ribonucleotide metabolic processGO:00092592310.016
neuron projection morphogenesisGO:00488121220.016
steroid metabolic processGO:0008202730.016
response to oxygen levelsGO:00704822650.016
regulation of cell projection organizationGO:00313441750.015
cellular response to insulin stimulusGO:0032869810.015
cell migrationGO:00164771970.015
regulation of nucleotide metabolic processGO:00061401170.015
regulation of mapk cascadeGO:00434081160.015
organic substance catabolic processGO:19015753160.015
intracellular transportGO:00469071850.015
small gtpase mediated signal transductionGO:0007264360.015
response to starvationGO:0042594590.015
hexose metabolic processGO:0019318580.015
neuromuscular synaptic transmissionGO:000727420.015
nucleoside triphosphate metabolic processGO:00091411440.015
carbohydrate derivative metabolic processGO:19011353460.015
gastrulationGO:000736920.015
nucleobase containing small molecule metabolic processGO:00550863160.015
regulation of secretionGO:00510462240.015
regulation of protein phosphorylationGO:00019321830.015
single organism behaviorGO:00447081300.015
vasculature developmentGO:0001944700.015
cell cycleGO:00070491010.015
response to electrical stimulusGO:0051602560.015
single organism carbohydrate metabolic processGO:00447231180.014
regulation of cell migrationGO:00303341280.014
organic acid metabolic processGO:00060822920.014
dephosphorylationGO:0016311980.014
olfactory learningGO:000835510.014
purine containing compound metabolic processGO:00725212530.014
inorganic cation transmembrane transportGO:00986622020.014
cellular potassium ion transportGO:0071804720.014
circadian regulation of gene expressionGO:003292230.014
circulatory system developmentGO:00723591340.014
regulation of rab protein signal transductionGO:003248330.014
positive regulation of cellular catabolic processGO:0031331710.014
energy derivation by oxidation of organic compoundsGO:0015980460.014
positive regulation of purine nucleotide metabolic processGO:1900544910.014
positive regulation of cellular amine metabolic processGO:003324030.014
regulation of cellular localizationGO:00603412630.014
calcium ion homeostasisGO:00550741620.014
amine metabolic processGO:0009308380.014
cytosolic calcium ion homeostasisGO:00514801400.014
divalent inorganic cation homeostasisGO:00725071650.014
maintenance of locationGO:0051235170.014
cellular response to interleukin 1GO:0071347370.014
positive regulation of cellular protein metabolic processGO:00322701670.013
secretionGO:00469033070.013
protein localizationGO:00081041910.013
response to activityGO:0014823730.013
sensory organ developmentGO:0007423740.013
aromatic compound catabolic processGO:00194391680.013
response to glucoseGO:00097491360.013
heart contractionGO:0060047570.013
cellular catabolic processGO:00442482950.013
cation transmembrane transportGO:00986552630.013
negative regulation of molecular functionGO:00440921330.013
regulation of metal ion transportGO:00109591180.013
nucleotide catabolic processGO:00091661390.013
positive regulation of multicellular organismal processGO:00512403870.013
growthGO:00400071650.013
regulation of muscle system processGO:0090257790.013
regulation of neurogenesisGO:00507672470.013
response to hydrogen peroxideGO:0042542890.013
positive regulation of phosphorylationGO:00423271770.013
positive regulation of cellular component organizationGO:00511302000.013
positive regulation of nucleotide metabolic processGO:0045981910.013
organophosphate catabolic processGO:00464341480.013
ncrna processingGO:003447030.013
regulation of neuron apoptotic processGO:0043523830.013
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.013
central nervous system developmentGO:00074173110.012
gamete generationGO:00072761240.012
regulation of cellular component movementGO:00512701500.012
regulation of growthGO:00400081050.012
dendrite morphogenesisGO:0048813430.012
chemosensory behaviorGO:000763520.012
dendrite developmentGO:0016358720.012
response to nutrientGO:00075842480.012
cellular response to growth factor stimulusGO:00713631620.012
norepinephrine metabolic processGO:004241530.012
phototransduction visible lightGO:000760320.012
nucleotide metabolic processGO:00091172790.012
negative regulation of cellular protein metabolic processGO:00322691060.012
chromosome segregationGO:000705920.012
ras protein signal transductionGO:0007265290.012
response to monosaccharideGO:00342841590.012
defense responseGO:00069521940.012
intracellular receptor signaling pathwayGO:0030522350.012
homeostatic processGO:00425923310.012
ribonucleoside triphosphate metabolic processGO:00091991410.012
protein phosphorylationGO:00064683450.012
regulation of canonical wnt signaling pathwayGO:006082840.012
positive regulation of rab gtpase activityGO:003285130.012
regulation of cell cycleGO:0051726730.012
positive regulation of gtp catabolic processGO:0033126480.012
signal transduction by phosphorylationGO:00230141440.012
peptidyl amino acid modificationGO:00181931260.012
blood circulationGO:00080151830.012
glycosyl compound metabolic processGO:19016571820.012
cation transportGO:00068123820.012
negative regulation of neuron apoptotic processGO:0043524450.012
epithelium developmentGO:0060429960.011
cellular protein complex assemblyGO:0043623440.011
programmed cell deathGO:00125013920.011
response to ethanolGO:00454711620.011
circulatory system processGO:00030131830.011
regulation of calcium ion transportGO:0051924770.011
ribonucleoside metabolic processGO:00091191740.011
generation of precursor metabolites and energyGO:0006091620.011
negative regulation of protein metabolic processGO:00512481140.011
cytoplasmic transportGO:00164821150.011
positive regulation of transferase activityGO:0051347810.011
response to organophosphorusGO:00466831020.011
secretion by cellGO:00329402480.011
g protein coupled receptor signaling pathwayGO:00071862420.011
lipid biosynthetic processGO:00086101280.011
regulation of protein kinase activityGO:00458591050.011
rna localizationGO:000640340.011
positive regulation of protein metabolic processGO:00512471780.011
monocarboxylic acid metabolic processGO:00327871520.011
multicellular organism growthGO:003526410.011
regulation of response to stressGO:00801341260.011
nitrogen compound transportGO:00717052290.011
anterior posterior pattern specificationGO:000995210.011
response to ionizing radiationGO:0010212590.011
regulation of transporter activityGO:0032409500.011
axis specificationGO:000979840.011
positive regulation of cellular amino acid metabolic processGO:004576410.011
cellular response to acid chemicalGO:0071229750.011
cellular macromolecular complex assemblyGO:0034622580.011
head developmentGO:00603222470.011
divalent inorganic cation transportGO:00725111340.011
ribonucleoside catabolic processGO:00424541260.011
response to ammonium ionGO:0060359710.011
macroautophagyGO:001623640.010
female pregnancyGO:00075651220.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
hormone secretionGO:00468791150.010
positive regulation of protein phosphorylationGO:00019341350.010
memoryGO:0007613540.010
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.010
olfactory behaviorGO:004204820.010
nucleoside metabolic processGO:00091161790.010
organonitrogen compound biosynthetic processGO:19015661670.010
positive regulation of cytosolic calcium ion concentrationGO:00072041220.010
regulation of kinase activityGO:00435491170.010
ribonucleoside triphosphate catabolic processGO:00092031220.010
sensory perception of light stimulusGO:005095330.010
regulation of protein modification processGO:00313991940.010
regulation of transcription elongation from rna polymerase ii promoterGO:003424340.010
gonad developmentGO:00084061040.010

Pi4k2a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.025
inherited metabolic disorderDOID:65500.022
nervous system diseaseDOID:86300.021
disease of anatomical entityDOID:700.021
musculoskeletal system diseaseDOID:1700.017
muscular diseaseDOID:008000000.016
muscle tissue diseaseDOID:6600.016
myopathyDOID:42300.012
central nervous system diseaseDOID:33100.012