Rattus norvegicus

19 known processes

Lum

lumican

Lum biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to mechanical stimulusGO:00096121340.809
Rat
growth plate cartilage developmentGO:000341720.598
extracellular matrix organizationGO:0030198130.591
Zebrafish
odontogenesisGO:0042476320.554
Rat
cartilage developmentGO:0051216220.510
cellular response to vitamin eGO:007130630.469
renal system developmentGO:0072001670.388
Rat
skeletal system developmentGO:0001501410.370
extracellular structure organizationGO:0043062130.337
Zebrafish
tissue developmentGO:00098882520.316
response to transforming growth factor betaGO:0071559460.310
anatomical structure morphogenesisGO:00096532980.306
Zebrafish Rat
response to campGO:0051591910.289
response to corticosteroidGO:00319602350.257
peptide cross linkingGO:001814910.255
cellular response to endogenous stimulusGO:00714953770.237
developmental growthGO:00485891000.215
response to nutrientGO:00075842480.215
cellular response to peptideGO:19016531330.207
response to growth factorGO:00708481890.206
response to fluorideGO:190261730.202
protein heterooligomerizationGO:0051291890.197
response to lipopolysaccharideGO:00324961910.185
Rat
endochondral bone growthGO:000341630.181
response to external biotic stimulusGO:00432072210.179
Rat
cellular response to organonitrogen compoundGO:00714171970.178
cellular response to fluorideGO:190261810.172
transforming growth factor beta receptor signaling pathwayGO:0007179180.171
response to biotic stimulusGO:00096072260.165
Rat
response to molecule of bacterial originGO:00022371940.162
Rat
muscle tissue developmentGO:0060537580.159
Rat
response to purine containing compoundGO:00140741260.158
response to inorganic substanceGO:00100353770.153
single organism reproductive processGO:00447022970.140
Rat
macromolecular complex subunit organizationGO:00439333390.138
Zebrafish
response to tumor necrosis factorGO:0034612560.136
response to nutrient levelsGO:00316673700.131
aorta developmentGO:003590420.126
cellular response to transforming growth factor beta stimulusGO:0071560410.126
response to vitamin eGO:0033197240.124
regulation of canonical wnt signaling pathwayGO:006082840.120
intracellular signal transductionGO:00355563140.119
response to other organismGO:00517072200.119
Rat
cellular response to hormone stimulusGO:00328702470.115
developmental growth involved in morphogenesisGO:0060560330.110
protein complex biogenesisGO:00702712630.109
reproductive structure developmentGO:00486081280.109
Rat
extracellular fibril organizationGO:004320610.108
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.107
cellular response to peptide hormone stimulusGO:00713751200.106
organ morphogenesisGO:0009887750.105
Zebrafish Rat
cellular response to organic cyclic compoundGO:00714072020.103
ossificationGO:0001503700.098
response to bacteriumGO:00096172000.097
Rat
endochondral bone morphogenesisGO:006035070.097
cellular component biogenesisGO:00440853680.096
placenta developmentGO:0001890220.095
Rat
cellular response to external stimulusGO:00714961180.094
cellular component assemblyGO:00226073600.090
protein complex subunit organizationGO:00718223020.090
Zebrafish
cellular response to nitrogen compoundGO:19016992100.089
organ growthGO:0035265240.088
macromolecular complex assemblyGO:00650032730.088
negative regulation of biomineral tissue developmentGO:007016820.085
agingGO:00075682410.084
Rat
response to peptideGO:19016522920.079
cellular response to alkaloidGO:0071312250.078
enzyme linked receptor protein signaling pathwayGO:00071671160.077
response to extracellular stimulusGO:00099913800.077
cellular response to growth factor stimulusGO:00713631620.076
skin morphogenesisGO:004358920.073
regulation of rna biosynthetic processGO:20011413810.072
Mouse
cellular response to oxygen containing compoundGO:19017013860.072
connective tissue developmentGO:0061448330.071
tooth eruptionGO:004469110.070
muscle organ developmentGO:0007517500.070
Rat
urogenital system developmentGO:0001655780.069
Rat
response to ionizing radiationGO:0010212590.068
response to peptide hormoneGO:00434342780.067
response to epidermal growth factorGO:0070849180.066
response to estrogenGO:00436272320.064
response to norepinephrineGO:007187350.063
sulfur compound metabolic processGO:0006790700.062
response to glucocorticoidGO:00513842230.061
cartilage development involved in endochondral bone morphogenesisGO:006035130.058
response to catecholamineGO:0071869160.058
kidney developmentGO:0001822670.058
Rat
cellular response to nicotineGO:007131670.058
development of primary sexual characteristicsGO:00451371070.058
embryonic skeletal system developmentGO:004870630.057
response to woundingGO:00096112540.056
Rat
response to oxygen levelsGO:00704822650.056
response to organophosphorusGO:00466831020.053
developmental process involved in reproductionGO:00030061590.053
Rat
cellular response to lipidGO:00713962010.052
protein phosphorylationGO:00064683450.052
response to hyperoxiaGO:0055093450.051
growthGO:00400071650.051
response to cytokineGO:00340972150.050
wound healingGO:00420601220.050
Rat
brain developmentGO:00074202470.049
regulation of transforming growth factor beta receptor signaling pathwayGO:001701550.047
response to radiationGO:00093141370.046
cellular ion homeostasisGO:00068731840.045
response to estradiolGO:00323551640.045
response to nicotineGO:0035094510.045
response to metal ionGO:00100382530.045
cellular cation homeostasisGO:00300031800.044
regulation of nervous system developmentGO:00519602640.044
endochondral ossificationGO:000195820.044
cellular response to tumor necrosis factorGO:0071356460.044
response to decreased oxygen levelsGO:00362932370.044
bone developmentGO:0060348250.044
response to x rayGO:0010165150.043
protein complex assemblyGO:00064612630.042
cellular response to mechanical stimulusGO:0071260480.042
response to monoamineGO:0071867170.041
response to vitaminGO:00332731310.041
cellular component movementGO:00069282480.041
response to oxidative stressGO:00069791860.040
cellular response to abiotic stimulusGO:0071214850.040
protein heterotrimerizationGO:007020820.040
collagen fibril organizationGO:003019910.039
Zebrafish
regulation of multicellular organismal developmentGO:20000263760.039
oxoacid metabolic processGO:00434362900.039
response to acid chemicalGO:00011012220.038
rho protein signal transductionGO:0007266110.037
striated muscle tissue developmentGO:0014706580.037
Rat
positive regulation of cellular biosynthetic processGO:00313282950.036
Mouse
chemical homeostasisGO:00488782920.036
cellular response to epidermal growth factor stimulusGO:0071364120.035
organic acid metabolic processGO:00060822920.035
cation homeostasisGO:00550801950.035
peptidyl amino acid modificationGO:00181931260.035
cellular response to extracellular stimulusGO:0031668730.034
negative regulation of cell developmentGO:0010721820.034
non canonical wnt signaling pathwayGO:003556730.034
response to increased oxygen levelsGO:0036296450.033
ion homeostasisGO:00508012120.033
action potentialGO:0001508540.033
cellular metal ion homeostasisGO:00068751720.032
response to fibroblast growth factorGO:0071774290.032
response to ethanolGO:00454711620.031
reproductionGO:00000032450.031
response to thyroid hormoneGO:0097066170.031
positive regulation of response to stimulusGO:00485842850.031
positive regulation of cellular component organizationGO:00511302000.031
g protein coupled receptor signaling pathwayGO:00071862420.031
cellular homeostasisGO:00197252520.031
cellular response to cytokine stimulusGO:00713451270.029
cellular response to acid chemicalGO:0071229750.029
response to glucoseGO:00097491360.029
muscle structure developmentGO:0061061870.029
Rat
response to hypoxiaGO:00016662310.028
macromolecule localizationGO:00330362520.028
regulation of cell differentiationGO:00455953200.027
cellular chemical homeostasisGO:00550822470.026
response to zinc ionGO:0010043390.026
positive regulation of macromolecule biosynthetic processGO:00105572470.026
Mouse
negative regulation of odontogenesisGO:004248310.026
cytolysisGO:001983540.026
regulation of transcription dna templatedGO:00063553740.026
Mouse
cellular response to stressGO:00335542690.026
response to alkaloidGO:00432791320.026
cellular response to thyroid hormone stimulusGO:009706750.025
regulation of signal transductionGO:00099663180.025
reproductive processGO:00224143720.025
Rat
positive regulation of gene expressionGO:00106282440.025
Mouse
small gtpase mediated signal transductionGO:0007264360.024
reproductive system developmentGO:00614581280.024
Rat
cellular response to nutrientGO:0031670300.024
rna biosynthetic processGO:00327743800.024
Mouse
regulation of hormone levelsGO:00108171870.024
vesicle mediated transportGO:00161921810.023
cellular response to vitaminGO:0071295210.023
immune system processGO:00023762040.023
apoptotic processGO:00069153810.023
metal ion homeostasisGO:00550651860.023
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.022
muscle organ morphogenesisGO:004864410.022
gonad developmentGO:00084061040.022
cellular response to nutrient levelsGO:0031669600.022
blood vessel developmentGO:0001568690.022
head developmentGO:00603222470.022
response to hydrogen peroxideGO:0042542890.022
positive regulation of cell differentiationGO:00455972170.021
cell motilityGO:00488702020.021
carbohydrate derivative metabolic processGO:19011353460.021
positive regulation of locomotionGO:00400171020.021
chondrocyte differentiationGO:0002062100.020
acrosome assemblyGO:000167530.020
tissue regenerationGO:0042246360.020
neuron projection developmentGO:00311752730.020
transcription dna templatedGO:00063513770.020
Mouse
cell projection organizationGO:00300303020.019
regulation of neurogenesisGO:00507672470.019
skeletal muscle tissue developmentGO:0007519310.019
Rat
regulation of cell developmentGO:00602842630.018
homeostatic processGO:00425923310.018
negative regulation of response to stimulusGO:00485851550.018
female pregnancyGO:00075651220.018
central nervous system developmentGO:00074173110.018
positive regulation of non canonical wnt signaling pathwayGO:200005210.018
negative regulation of signalingGO:00230571570.018
peptidyl serine modificationGO:0018209340.018
single organism biosynthetic processGO:00447113420.018
myeloid leukocyte activationGO:0002274360.018
positive regulation of developmental processGO:00510942830.018
anatomical structure formation involved in morphogenesisGO:0048646830.018
biological adhesionGO:00226101100.017
ras protein signal transductionGO:0007265290.017
endoplasmic reticulum to cytosol transportGO:190351340.017
axis elongationGO:000340120.017
protein oligomerizationGO:00512591910.017
proteoglycan metabolic processGO:000602930.017
skeletal muscle organ developmentGO:0060538330.016
Rat
rna metabolic processGO:00160704060.016
Mouse
neuron differentiationGO:00301823680.016
eye morphogenesisGO:004859240.016
Zebrafish
formation of primary germ layerGO:000170410.016
positive regulation of protein modification processGO:00314011420.016
negative regulation of multicellular organismal processGO:00512412030.015
positive regulation of cellular component biogenesisGO:0044089550.015
elastic fiber assemblyGO:004825110.015
response to retinoic acidGO:0032526630.015
regulation of odontogenesisGO:004248140.015
multicellular organism reproductionGO:00325042330.015
response to reactive oxygen speciesGO:00003021200.015
digestive tract developmentGO:0048565390.015
erbb signaling pathwayGO:0038127230.014
regenerationGO:00310991630.014
neuron developmentGO:00486662860.014
response to amino acidGO:0043200750.014
positive regulation of immune responseGO:0050778420.014
regulation of cell proliferationGO:00421273590.014
cellular amine metabolic processGO:0044106380.014
regulation of protein metabolic processGO:00512462890.014
response to carbohydrateGO:00097431830.014
regulation of molecular functionGO:00650093980.014
visual perceptionGO:000760130.013
response to hexoseGO:00097461440.013
rhythmic processGO:00485111560.013
cellular hormone metabolic processGO:0034754490.013
negative regulation of neurogenesisGO:0050768780.013
lipid biosynthetic processGO:00086101280.013
bone morphogenesisGO:0060349110.013
cell adhesionGO:00071551100.013
cellular response to retinoic acidGO:0071300270.013
regulation of rna metabolic processGO:00512523910.013
Mouse
cellular component morphogenesisGO:00329891550.013
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051220.013
eye developmentGO:0001654500.013
Zebrafish
locomotionGO:00400112370.013
positive regulation of nucleobase containing compound metabolic processGO:00459353190.013
Mouse
response to monosaccharideGO:00342841590.013
skin developmentGO:0043588170.013
immune responseGO:00069551040.013
circadian rhythmGO:0007623880.013
regulation of nucleic acid templated transcriptionGO:19035063800.013
Mouse
blood vessel morphogenesisGO:0048514580.013
multicellular organismal signalingGO:0035637440.013
organic substance catabolic processGO:19015753160.012
artery developmentGO:006084030.012
negative regulation of cell proliferationGO:00082851190.012
hormone metabolic processGO:0042445690.012
regulation of growthGO:00400081050.012
regulation of apoptotic processGO:00429813350.012
negative regulation of developmental processGO:00510931250.012
regulation of immune responseGO:0050776550.012
catabolic processGO:00090563510.012
sex differentiationGO:00075481130.012
establishment of planar polarityGO:000173610.012
positive regulation of phosphate metabolic processGO:00459372620.012
protein localization to organelleGO:0033365570.012
response to indole 3 methanolGO:007168020.012
epithelium developmentGO:0060429960.011
positive regulation of nucleic acid templated transcriptionGO:19035081970.011
Mouse
organ regenerationGO:00311001010.011
nucleic acid templated transcriptionGO:00976593790.011
Mouse
regulation of cellular component organizationGO:00511283680.011
development of primary female sexual characteristicsGO:0046545560.011
replacement ossificationGO:003607520.011
negative regulation of cell communicationGO:00106481580.011
regulation of response to stressGO:00801341260.011
neurological system processGO:00508772190.010
negative regulation of macromolecule biosynthetic processGO:00105581480.010
cellular macromolecule localizationGO:00707271220.010
positive regulation of multicellular organismal processGO:00512403870.010
positive regulation of transcription dna templatedGO:00458931970.010
Mouse
regulation of cellular localizationGO:00603412630.010
neuronal action potentialGO:0019228350.010
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.010
regulation of anatomical structure morphogenesisGO:00226031410.010
positive regulation of rna metabolic processGO:00512542030.010
Mouse
cellular sodium ion homeostasisGO:000688340.010

Lum disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.132
connective tissue diseaseDOID:6500.132
musculoskeletal system diseaseDOID:1700.132
ehlers danlos syndromeDOID:1335900.132
collagen diseaseDOID:85400.132
bone development diseaseDOID:008000600.061
bone diseaseDOID:008000100.061
osteochondrodysplasiaDOID:225600.061
osteogenesis imperfectaDOID:1234700.024
nervous system diseaseDOID:86300.012