Rattus norvegicus

92 known processes

Grem1

gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)

(Aliases: drm,Cktsf1b1)

Grem1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to peptide hormoneGO:00434342780.332
response to peptideGO:19016522920.231
programmed cell deathGO:00125013920.157
apoptotic processGO:00069153810.153
neurological system processGO:00508772190.141
cellular response to endogenous stimulusGO:00714953770.137
regulation of programmed cell deathGO:00430673410.124
regulation of apoptotic processGO:00429813350.118
reproductive processGO:00224143720.117
response to extracellular stimulusGO:00099913800.111
cellular component movementGO:00069282480.110
response to toxic substanceGO:00096361330.090
cellular response to organic cyclic compoundGO:00714072020.090
response to estrogenGO:00436272320.085
blood circulationGO:00080151830.083
organic acid metabolic processGO:00060822920.079
cellular response to hormone stimulusGO:00328702470.077
chemical homeostasisGO:00488782920.077
reproductive system developmentGO:00614581280.073
response to inorganic substanceGO:00100353770.071
response to mechanical stimulusGO:00096121340.068
ovulation cycle processGO:0022602500.067
reproductionGO:00000032450.067
proteolysisGO:00065081750.065
response to acid chemicalGO:00011012220.064
response to insulinGO:00328681330.064
positive regulation of nitrogen compound metabolic processGO:00511733340.063
regulation of blood circulationGO:19035221100.063
regulation of response to stressGO:00801341260.062
response to nutrient levelsGO:00316673700.060
regulation of blood pressureGO:0008217830.060
neuron differentiationGO:00301823680.060
multi multicellular organism processGO:00447061380.060
positive regulation of biosynthetic processGO:00098913190.059
regulation of cell growthGO:0001558850.058
multicellular organismal reproductive processGO:00486092330.057
positive regulation of cellular biosynthetic processGO:00313282950.057
cellular response to alcoholGO:0097306870.056
regulation of molecular functionGO:00650093980.056
single organism reproductive processGO:00447022970.056
cellular response to stressGO:00335542690.055
neuron neuron synaptic transmissionGO:0007270600.055
regulation of fat cell differentiationGO:004559830.054
response to nutrientGO:00075842480.054
neuron developmentGO:00486662860.053
behaviorGO:00076102050.053
regulation of tube sizeGO:0035150890.053
response to ketoneGO:19016541820.053
positive regulation of apoptotic processGO:00430651540.053
positive regulation of transportGO:00510502450.053
rhythmic processGO:00485111560.052
negative regulation of cell deathGO:00605482290.052
response to estradiolGO:00323551640.052
cell cell signalingGO:00072673350.052
response to alkaloidGO:00432791320.051
regulation of ion transportGO:00432692450.051
cellular cation homeostasisGO:00300031800.051
response to purine containing compoundGO:00140741260.051
negative regulation of metabolic processGO:00098923310.051
regulation of transcription dna templatedGO:00063553740.050
synaptic transmissionGO:00072682350.050
cation transportGO:00068123820.050
regulation of multicellular organismal developmentGO:20000263760.049
metal ion transportGO:00300012890.049
neuron projection developmentGO:00311752730.049
positive regulation of macromolecule biosynthetic processGO:00105572470.048
carboxylic acid metabolic processGO:00197522890.048
cell projection organizationGO:00300303020.047
positive regulation of developmental processGO:00510942830.047
cellular response to oxygen containing compoundGO:19017013860.047
cellular response to peptide hormone stimulusGO:00713751200.046
positive regulation of gene expressionGO:00106282440.046
regulation of locomotionGO:00400121480.046
positive regulation of multicellular organismal processGO:00512403870.045
cell growthGO:00160491040.045
negative regulation of programmed cell deathGO:00430691830.044
positive regulation of transcription factor import into nucleusGO:004299340.044
organelle organizationGO:00069962660.044
tube developmentGO:0035295890.044
positive regulation of cell deathGO:00109421840.043
cellular response to peptideGO:19016531330.043
positive regulation of intracellular protein transportGO:0090316200.043
defense responseGO:00069521940.043
anion transportGO:00068201780.042
brain developmentGO:00074202470.041
response to oxidative stressGO:00069791860.041
positive regulation of cell proliferationGO:00082842490.040
multi organism reproductive processGO:00447032620.040
ovulation cycleGO:0042698670.040
response to ethanolGO:00454711620.039
positive regulation of cellular component organizationGO:00511302000.039
positive regulation of programmed cell deathGO:00430681570.039
regulation of cellular component movementGO:00512701500.039
cell migrationGO:00164771970.039
cellular response to abiotic stimulusGO:0071214850.039
motor neuron axon guidanceGO:000804510.038
central nervous system developmentGO:00074173110.038
regulation of cell proliferationGO:00421273590.038
regulation of system processGO:00440572080.037
response to other organismGO:00517072200.036
divalent inorganic cation homeostasisGO:00725071650.036
nucleic acid templated transcriptionGO:00976593790.036
cell part morphogenesisGO:00329901230.036
negative regulation of multicellular organismal processGO:00512412030.036
neuron deathGO:00709971270.036
regulation of systemic arterial blood pressureGO:0003073300.035
estrous cycle phaseGO:0060206150.035
cell morphogenesisGO:00009021420.035
lipid biosynthetic processGO:00086101280.035
cellular homeostasisGO:00197252520.034
single organism carbohydrate metabolic processGO:00447231180.034
regulation of blood vessel sizeGO:0050880890.034
lipid metabolic processGO:00066292830.034
regulation of muscle contractionGO:0006937530.034
protein complex biogenesisGO:00702712630.033
rna biosynthetic processGO:00327743800.033
metanephric comma shaped body morphogenesisGO:007227820.033
cellular ketone metabolic processGO:0042180510.033
muscle contractionGO:0006936880.032
response to molecule of bacterial originGO:00022371940.032
head developmentGO:00603222470.032
regulation of hydrolase activityGO:00513361430.032
cellular response to acid chemicalGO:0071229750.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.032
regulation of catalytic activityGO:00507903040.032
regulation of anatomical structure sizeGO:00900661350.032
oxoacid metabolic processGO:00434362900.032
regulation of transcription from rna polymerase ii promoterGO:00063572340.032
agingGO:00075682410.031
inflammatory responseGO:00069541500.031
circulatory system processGO:00030131830.031
cellular response to external stimulusGO:00714961180.030
single organism biosynthetic processGO:00447113420.030
cellular component biogenesisGO:00440853680.030
regulation of nucleic acid templated transcriptionGO:19035063800.030
cell motilityGO:00488702020.029
rna metabolic processGO:00160704060.029
locomotionGO:00400112370.029
cation homeostasisGO:00550801950.029
positive regulation of molecular functionGO:00440932300.029
protein complex assemblyGO:00064612630.029
gastrulationGO:000736920.029
learning or memoryGO:0007611900.028
regulation of response to external stimulusGO:00321011060.028
female gonad developmentGO:0008585530.028
negative regulation of apoptotic processGO:00430661810.028
phasic smooth muscle contractionGO:001482130.028
regulation of cellular component organizationGO:00511283680.028
positive regulation of catalytic activityGO:00430851840.027
response to amino acidGO:0043200750.027
brain renin angiotensin systemGO:000203530.027
negative regulation of biosynthetic processGO:00098901680.027
regulation of lipid metabolic processGO:0019216680.027
cell morphogenesis involved in differentiationGO:00009041190.027
reactive oxygen species metabolic processGO:0072593370.027
negative regulation of rna biosynthetic processGO:19026791180.026
single organism behaviorGO:00447081300.026
positive regulation of rna metabolic processGO:00512542030.026
nitrogen compound transportGO:00717052290.026
muscle system processGO:00030121150.026
endocrine processGO:0050886320.025
positive regulation of signalingGO:00230562700.025
secretionGO:00469033070.025
regulation of rna biosynthetic processGO:20011413810.025
protein phosphorylationGO:00064683450.025
response to increased oxygen levelsGO:0036296450.025
tissue developmentGO:00098882520.025
carbohydrate metabolic processGO:00059751300.024
cardiovascular system developmentGO:00723581340.024
positive regulation of phosphorylationGO:00423271770.024
response to oxygen levelsGO:00704822650.024
sodium ion transportGO:0006814820.024
regulation of cell differentiationGO:00455953200.024
regulation of heart rateGO:0002027160.024
positive regulation of cell growthGO:0030307440.024
negative regulation of gene expressionGO:00106291990.024
reproductive structure developmentGO:00486081280.024
heart processGO:0003015570.024
response to metal ionGO:00100382530.024
positive regulation of heart contractionGO:0045823150.024
positive regulation of cell migrationGO:0030335960.023
amine metabolic processGO:0009308380.023
response to growth factorGO:00708481890.023
regulation of cell motilityGO:20001451310.023
regulation of synaptic transmissionGO:00508041410.023
response to amineGO:0014075460.023
positive regulation of lipid kinase activityGO:009021820.023
response to heatGO:0009408600.023
regulation of amino acid transportGO:0051955250.023
regulation of protein metabolic processGO:00512462890.023
positive regulation of saliva secretionGO:004687830.023
response to electrical stimulusGO:0051602560.023
cell cycleGO:00070491010.023
cellular component assemblyGO:00226073600.023
regulation of rna metabolic processGO:00512523910.023
regulation of organic acid transportGO:0032890350.023
regulation of cellular amine metabolic processGO:003323880.022
smooth muscle cell proliferationGO:0048659770.022
response to decreased oxygen levelsGO:00362932370.022
response to woundingGO:00096112540.022
negative regulation of cellular biosynthetic processGO:00313271610.022
positive regulation of homeostatic processGO:0032846490.022
positive regulation of muscle contractionGO:0045933220.022
response to organophosphorusGO:00466831020.021
cellular response to growth factor stimulusGO:00713631620.021
axon developmentGO:0061564960.021
renin secretion into blood streamGO:000200110.021
sexual reproductionGO:00199531480.021
regulation of muscle system processGO:0090257790.021
response to osmotic stressGO:0006970420.021
gland developmentGO:00487321550.021
immune system processGO:00023762040.021
cellular amine metabolic processGO:0044106380.021
growthGO:00400071650.021
macromolecular complex subunit organizationGO:00439333390.021
response to external biotic stimulusGO:00432072210.021
cellular response to organonitrogen compoundGO:00714171970.020
response to temperature stimulusGO:0009266940.020
calcium ion transportGO:00068161310.020
peptidyl amino acid modificationGO:00181931260.020
regulation of cellular protein metabolic processGO:00322682670.020
vascular process in circulatory systemGO:0003018960.020
transcription from rna polymerase ii promoterGO:00063662520.020
positive regulation of phosphorus metabolic processGO:00105622620.020
regulation of proteasomal protein catabolic processGO:006113640.020
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.020
homeostatic processGO:00425923310.020
negative regulation of macromolecule metabolic processGO:00106052600.020
peptide hormone secretionGO:0030072840.020
cytosolic calcium ion homeostasisGO:00514801400.020
response to nicotineGO:0035094510.020
positive regulation of fat cell differentiationGO:004560020.020
regulation of cellular amino acid metabolic processGO:000652120.020
embryonic pattern specificationGO:000988010.019
protein processingGO:0016485680.019
response to corticosteroidGO:00319602350.019
vasoconstrictionGO:0042310540.019
formation of primary germ layerGO:000170410.019
cellular response to nitrogen compoundGO:19016992100.019
ion homeostasisGO:00508012120.019
positive regulation of blood circulationGO:1903524650.019
positive regulation of transcription dna templatedGO:00458931970.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.019
muscle cell proliferationGO:0033002840.018
positive regulation of rna biosynthetic processGO:19026801970.018
acid secretionGO:0046717480.018
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.018
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.018
forebrain developmentGO:0030900980.018
regulation of cell projection organizationGO:00313441750.018
smooth muscle contractionGO:0006939370.018
cellular amino acid metabolic processGO:00065201070.018
positive regulation of phosphate metabolic processGO:00459372620.018
macromolecular complex assemblyGO:00650032730.018
regulation of feeding behaviorGO:0060259140.018
regulation of defense responseGO:0031347680.017
localization of cellGO:00516742020.017
regulation of vasoconstrictionGO:0019229440.017
multicellular organism reproductionGO:00325042330.017
positive regulation of hormone secretionGO:0046887650.017
single organism organelle organizationGO:19025891800.017
regulation of reactive oxygen species biosynthetic processGO:190342650.017
reactive oxygen species biosynthetic processGO:190340980.017
reactive nitrogen species metabolic processGO:200105710.017
response to glucocorticoidGO:00513842230.017
regulation of hormone levelsGO:00108171870.017
cellular calcium ion homeostasisGO:00068741600.017
dendrite developmentGO:0016358720.017
positive regulation of secretionGO:00510471400.017
regulation of cellular catabolic processGO:00313291010.017
carbohydrate derivative metabolic processGO:19011353460.017
positive regulation of protein phosphorylationGO:00019341350.017
regulation of reactive oxygen species metabolic processGO:2000377260.017
acute inflammatory responseGO:0002526580.017
positive regulation of action potentialGO:004576080.017
regulation of response to woundingGO:1903034690.016
response to biotic stimulusGO:00096072260.016
regulation of amine transportGO:0051952540.016
signal releaseGO:00230611450.016
carboxylic acid biosynthetic processGO:0046394830.016
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.016
monocarboxylic acid metabolic processGO:00327871520.016
s shaped body morphogenesisGO:007205020.016
regulation of cellular ketone metabolic processGO:0010565270.016
response to cytokineGO:00340972150.016
membrane organizationGO:0061024940.016
membrane repolarizationGO:008600910.016
response to carbohydrateGO:00097431830.016
organic hydroxy compound metabolic processGO:19016151150.016
cognitionGO:0050890920.016
response to testosteroneGO:0033574550.016
positive regulation of synaptic transmissionGO:0050806620.016
organic substance catabolic processGO:19015753160.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
axis specificationGO:000979840.016
regulation of cellular component biogenesisGO:0044087860.016
regulation of body fluid levelsGO:0050878900.015
regulation of anion transportGO:0044070430.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
positive regulation of nf kappab import into nucleusGO:004234620.015
regulation of inflammatory responseGO:0050727480.015
regulation of signal transductionGO:00099663180.015
regulation of metanephros developmentGO:007221540.015
organic acid biosynthetic processGO:0016053830.015
intracellular transportGO:00469071850.015
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.015
regulation of catabolic processGO:00098941130.015
developmental process involved in reproductionGO:00030061590.015
regulation of growthGO:00400081050.015
regulation of transferase activityGO:00513381230.015
female sex differentiationGO:0046660590.015
action potentialGO:0001508540.015
transcription dna templatedGO:00063513770.015
intracellular signal transductionGO:00355563140.015
peptide transportGO:0015833970.015
oxidation reduction processGO:00551143040.015
metal ion homeostasisGO:00550651860.015
cellular response to mechanical stimulusGO:0071260480.015
negative regulation of signalingGO:00230571570.015
steroid metabolic processGO:0008202730.015
hair cycle processGO:002240520.014
urinary tract smooth muscle contractionGO:001484840.014
amide transportGO:00428861050.014
epithelium developmentGO:0060429960.014
cellular response to steroid hormone stimulusGO:0071383930.014
circulatory system developmentGO:00723591340.014
response to ammonium ionGO:0060359710.014
urinary bladder smooth muscle contractionGO:001483240.014
regulation of homeostatic processGO:00328441010.014
regulation of anatomical structure morphogenesisGO:00226031410.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
cell morphogenesis involved in neuron differentiationGO:00486671060.014
leukocyte activationGO:0045321760.014
cellular metal ion homeostasisGO:00068751720.014
positive regulation of response to stimulusGO:00485842850.014
regulation of phosphate metabolic processGO:00192203490.014
neurotransmitter gated ion channel clusteringGO:007257830.014
hair follicle developmentGO:000194220.014
regulation of secretionGO:00510462240.014
monocarboxylic acid biosynthetic processGO:0072330480.013
amino acid transportGO:0006865700.013
positive regulation of cell communicationGO:00106472710.013
response to campGO:0051591910.013
regulation of ion homeostasisGO:2000021630.013
cellular response to drugGO:0035690300.013
dna metabolic processGO:0006259960.013
response to progesteroneGO:0032570480.013
regulation of dendrite developmentGO:0050773590.013
b cell differentiationGO:003018320.013
purine nucleotide metabolic processGO:00061632290.013
acute phase responseGO:0006953200.013
regulation of phosphorylationGO:00423252480.013
positive regulation of cellular protein metabolic processGO:00322701670.013
regulation of cellular localizationGO:00603412630.013
macromolecule localizationGO:00330362520.013
comma shaped body morphogenesisGO:007204920.013
thyroid gland developmentGO:003087810.013
positive regulation of smooth muscle contractionGO:0045987180.013
positive regulation of cell differentiationGO:00455972170.013
positive regulation of organelle organizationGO:0010638480.013
positive regulation of cytoplasmic transportGO:1903651320.013
negative regulation of nitrogen compound metabolic processGO:00511721610.013
negative regulation of developmental processGO:00510931250.013
cellular component morphogenesisGO:00329891550.013
appendage morphogenesisGO:003510740.013
memoryGO:0007613540.012
mapk cascadeGO:00001651400.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
branching morphogenesis of an epithelial tubeGO:0048754140.012
regulation of lipid biosynthetic processGO:0046890380.012
negative regulation of cellular protein metabolic processGO:00322691060.012
secretion by cellGO:00329402480.012
potassium ion transportGO:0006813970.012
response to lipopolysaccharideGO:00324961910.012
cytoskeleton organizationGO:00070101110.012
anatomical structure morphogenesisGO:00096532980.012
regulation of oxidoreductase activityGO:0051341110.012
muscle structure developmentGO:0061061870.012
fatty acid metabolic processGO:0006631990.012
positive regulation of cellular component biogenesisGO:0044089550.012
response to dexamethasoneGO:0071548490.012
neuromuscular processGO:005090520.012
protein complex subunit organizationGO:00718223020.012
renal system processGO:0003014400.012
regulation of cell developmentGO:00602842630.012
regulation of cell cycleGO:0051726730.012
purine ribonucleoside metabolic processGO:00461281680.012
b cell activation involved in immune responseGO:000231210.012
cardiac conductionGO:006133720.012
dephosphorylationGO:0016311980.012
epithelial cell migrationGO:0010631190.012
cellular response to insulin stimulusGO:0032869810.012
sex differentiationGO:00075481130.012
neuron projection morphogenesisGO:00488121220.012
regulation of exit from mitosisGO:000709610.012
mesoderm developmentGO:000749820.011
regulation of heart contractionGO:0008016480.011
regulation of peptide hormone secretionGO:0090276800.011
developmental growthGO:00485891000.011
skin developmentGO:0043588170.011
divalent metal ion transportGO:00708381320.011
regulation of renin secretion into blood streamGO:190013310.011
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.011
saliva secretionGO:004654130.011
regulation of immune response to tumor cellGO:000283730.011
regulation of phosphorus metabolic processGO:00511743490.011
gonad developmentGO:00084061040.011
regulation of purine nucleotide metabolic processGO:19005421150.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
carbohydrate derivative biosynthetic processGO:19011371240.011
response to activityGO:0014823730.011
organophosphate metabolic processGO:00196373700.011
regulation of smooth muscle cell proliferationGO:0048660750.011
ras protein signal transductionGO:0007265290.011
signal transduction by phosphorylationGO:00230141440.011
biological phaseGO:0044848170.011
cell communication involved in cardiac conductionGO:008606520.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
negative regulation of intracellular estrogen receptor signaling pathwayGO:003314720.011
positive regulation of cellular amine metabolic processGO:003324030.011
regulation of cellular response to stressGO:0080135490.011
response to hexoseGO:00097461440.011
negative regulation of catalytic activityGO:00430861030.011
amine transportGO:0015837570.011
negative regulation of transcription dna templatedGO:00458921160.011
divalent inorganic cation transportGO:00725111340.011
positive regulation of catabolic processGO:0009896780.011
positive regulation of protein metabolic processGO:00512471780.011
negative regulation of glutamate secretionGO:001405090.011
maternal process involved in female pregnancyGO:0060135380.011
transmembrane transportGO:00550854120.011
epithelial cell proliferationGO:0050673540.010
cellular carbohydrate metabolic processGO:0044262720.010
organic anion transportGO:00157111320.010
male gamete generationGO:0048232990.010
negative regulation of growthGO:0045926370.010
regulation of smooth muscle contractionGO:0006940290.010
cellular ion homeostasisGO:00068731840.010
cellular amino acid biosynthetic processGO:0008652320.010
negative regulation of molecular functionGO:00440921330.010
protein maturationGO:0051604680.010
heart morphogenesisGO:000300730.010
regulation of proteolysisGO:0030162660.010
negative regulation of nucleobase containing compound metabolic processGO:00459341530.010

Grem1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
urinary system diseaseDOID:1800.027
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.024
brain diseaseDOID:93600.024
central nervous system diseaseDOID:33100.024
disease of metabolismDOID:001466700.014
long qt syndromeDOID:284300.013