Rattus norvegicus

139 known processes

Pten

phosphatase and tensin homolog

(Aliases: Mmac,TEP1,MMAC1)

Pten biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein phosphorylationGO:00064683450.161
Human
regulation of protein metabolic processGO:00512462890.138
Human
regulation of molecular functionGO:00650093980.127
Human
catabolic processGO:00090563510.117
Human
negative regulation of cellular metabolic processGO:00313242810.114
Human
programmed cell deathGO:00125013920.105
transcription dna templatedGO:00063513770.101
Human
rna metabolic processGO:00160704060.099
Human
response to nutrientGO:00075842480.093
regulation of apoptotic processGO:00429813350.092
cellular catabolic processGO:00442482950.080
Human
regulation of transcription dna templatedGO:00063553740.074
Human
regulation of cellular component organizationGO:00511283680.071
transmembrane transportGO:00550854120.065
regulation of catalytic activityGO:00507903040.064
Human
regulation of phosphorus metabolic processGO:00511743490.063
Human
organic substance catabolic processGO:19015753160.062
Human
regulation of rna biosynthetic processGO:20011413810.062
Human
negative regulation of macromolecule metabolic processGO:00106052600.060
Human
regulation of rna metabolic processGO:00512523910.060
Human
positive regulation of transportGO:00510502450.058
reproductionGO:00000032450.057
regulation of cellular protein metabolic processGO:00322682670.057
Human
nucleic acid templated transcriptionGO:00976593790.056
Human
negative regulation of metabolic processGO:00098923310.055
Human
reproductive processGO:00224143720.055
response to biotic stimulusGO:00096072260.054
response to estrogenGO:00436272320.053
regulation of response to stressGO:00801341260.050
multi organism reproductive processGO:00447032620.048
regulation of signal transductionGO:00099663180.048
Human
negative regulation of cell communicationGO:00106481580.048
regulation of phosphate metabolic processGO:00192203490.046
Human
positive regulation of molecular functionGO:00440932300.045
Human
regulation of transcription from rna polymerase ii promoterGO:00063572340.045
protein catabolic processGO:0030163300.045
Human
cellular response to endogenous stimulusGO:00714953770.044
negative regulation of programmed cell deathGO:00430691830.044
cellular response to hormone stimulusGO:00328702470.044
regulation of secretion by cellGO:19035302080.043
intracellular signal transductionGO:00355563140.042
Human
regulation of nucleic acid templated transcriptionGO:19035063800.041
Human
proteolysisGO:00065081750.041
Human
regulation of ion transportGO:00432692450.041
positive regulation of biosynthetic processGO:00098913190.040
cellular component biogenesisGO:00440853680.039
Human
cellular ketone metabolic processGO:0042180510.039
protein autophosphorylationGO:0046777660.038
enzyme linked receptor protein signaling pathwayGO:00071671160.038
negative regulation of gene expressionGO:00106291990.037
multicellular organism reproductionGO:00325042330.037
ion transmembrane transportGO:00342203650.037
apoptotic processGO:00069153810.037
tissue developmentGO:00098882520.036
regulation of secretionGO:00510462240.036
defense responseGO:00069521940.036
macromolecule localizationGO:00330362520.036
cellular component assemblyGO:00226073600.036
Human
cellular response to stressGO:00335542690.036
single organism reproductive processGO:00447022970.036
brain developmentGO:00074202470.035
response to extracellular stimulusGO:00099913800.034
macromolecular complex assemblyGO:00650032730.034
lipid metabolic processGO:00066292830.034
response to external biotic stimulusGO:00432072210.033
cellular response to peptide hormone stimulusGO:00713751200.033
cellular response to oxygen containing compoundGO:19017013860.033
response to ethanolGO:00454711620.033
behaviorGO:00076102050.033
transcription from rna polymerase ii promoterGO:00063662520.032
central nervous system developmentGO:00074173110.032
response to inorganic substanceGO:00100353770.032
bmp signaling pathwayGO:003050940.032
secretionGO:00469033070.032
regulation of cellular localizationGO:00603412630.031
cellular response to nitrogen compoundGO:19016992100.031
negative regulation of molecular functionGO:00440921330.031
Human
regulation of kinase activityGO:00435491170.030
Human
actin filament based processGO:0030029860.030
carboxylic acid metabolic processGO:00197522890.030
positive regulation of nucleobase containing compound metabolic processGO:00459353190.030
regulation of cellular catabolic processGO:00313291010.030
Human
positive regulation of phosphorus metabolic processGO:00105622620.030
rna biosynthetic processGO:00327743800.030
Human
negative regulation of apoptotic processGO:00430661810.029
cation transportGO:00068123820.029
positive regulation of cellular protein metabolic processGO:00322701670.029
Human
multicellular organismal reproductive processGO:00486092330.029
positive regulation of cellular component organizationGO:00511302000.029
Human
regulation of mapk cascadeGO:00434081160.029
oxoacid metabolic processGO:00434362900.028
positive regulation of cell communicationGO:00106472710.028
positive regulation of cellular biosynthetic processGO:00313282950.028
negative regulation of signalingGO:00230571570.028
developmental process involved in reproductionGO:00030061590.028
regulation of multicellular organismal developmentGO:20000263760.028
nitrogen compound transportGO:00717052290.028
regulation of cytokine productionGO:0001817560.028
signal transduction by phosphorylationGO:00230141440.027
response to radiationGO:00093141370.027
negative regulation of signal transductionGO:0009968830.027
Human
organic acid metabolic processGO:00060822920.027
anatomical structure morphogenesisGO:00096532980.026
organic cyclic compound catabolic processGO:19013611750.026
response to other organismGO:00517072200.026
homeostatic processGO:00425923310.026
regulation of cell proliferationGO:00421273590.026
response to glucocorticoidGO:00513842230.025
secretion by cellGO:00329402480.025
neuron developmentGO:00486662860.025
regulation of cellular ketone metabolic processGO:0010565270.025
cellular amino acid metabolic processGO:00065201070.025
response to toxic substanceGO:00096361330.025
positive regulation of signalingGO:00230562700.024
ribonucleotide metabolic processGO:00092592310.024
positive regulation of cell proliferationGO:00082842490.024
regulation of phosphorylationGO:00423252480.024
Human
locomotionGO:00400112370.024
Human
positive regulation of protein metabolic processGO:00512471780.024
Human
regulation of protein localizationGO:0032880810.024
regulation of protein transportGO:0051223680.024
positive regulation of multicellular organismal processGO:00512403870.024
purine ribonucleotide metabolic processGO:00091502270.023
response to cytokineGO:00340972150.023
metal ion transportGO:00300012890.023
response to growth factorGO:00708481890.023
negative regulation of cellular biosynthetic processGO:00313271610.023
positive regulation of nitrogen compound metabolic processGO:00511733340.023
response to nutrient levelsGO:00316673700.023
muscle cell proliferationGO:0033002840.023
response to peptideGO:19016522920.023
cell motilityGO:00488702020.022
Human
negative regulation of biosynthetic processGO:00098901680.022
cell cell signalingGO:00072673350.022
cellular chemical homeostasisGO:00550822470.022
nucleobase containing compound catabolic processGO:00346551520.022
regulation of programmed cell deathGO:00430673410.022
ion homeostasisGO:00508012120.021
head developmentGO:00603222470.021
neurological system processGO:00508772190.021
regulation of response to external stimulusGO:00321011060.021
cellular homeostasisGO:00197252520.021
cellular response to organonitrogen compoundGO:00714171970.021
dephosphorylationGO:0016311980.021
cation transmembrane transportGO:00986552630.021
response to woundingGO:00096112540.021
response to bacteriumGO:00096172000.021
inorganic cation transmembrane transportGO:00986622020.021
response to corticosteroidGO:00319602350.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
regulation of endocytosisGO:0030100420.020
wound healingGO:00420601220.020
peptidyl amino acid modificationGO:00181931260.020
positive regulation of phosphate metabolic processGO:00459372620.020
purine containing compound metabolic processGO:00725212530.020
regulation of transferase activityGO:00513381230.020
Human
neuron differentiationGO:00301823680.020
heterocycle catabolic processGO:00467001670.019
cellular response to growth factor stimulusGO:00713631620.019
amine metabolic processGO:0009308380.019
heart developmentGO:0007507720.019
positive regulation of developmental processGO:00510942830.019
anion transportGO:00068201780.019
response to peptide hormoneGO:00434342780.019
regulation of cellular amino acid metabolic processGO:000652120.019
ribose phosphate metabolic processGO:00196932350.019
immune system processGO:00023762040.019
regulation of cellular amine metabolic processGO:003323880.019
positive regulation of phosphorylationGO:00423271770.019
actin cytoskeleton organizationGO:0030036730.019
positive regulation of signal transductionGO:00099671750.019
smooth muscle cell proliferationGO:0048659770.019
positive regulation of cell deathGO:00109421840.019
macromolecular complex subunit organizationGO:00439333390.019
negative regulation of rna metabolic processGO:00512531230.019
regulation of protein modification processGO:00313991940.019
Human
response to light stimulusGO:0009416520.019
regulation of hormone levelsGO:00108171870.019
response to alkaloidGO:00432791320.018
positive regulation of gene expressionGO:00106282440.018
nucleotide metabolic processGO:00091172790.018
intracellular transportGO:00469071850.018
multi multicellular organism processGO:00447061380.018
regulation of purine nucleotide metabolic processGO:19005421150.018
regulation of body fluid levelsGO:0050878900.018
negative regulation of protein metabolic processGO:00512481140.018
Human
regulation of cell cycleGO:0051726730.018
Human
sexual reproductionGO:00199531480.018
metal ion homeostasisGO:00550651860.018
chemical homeostasisGO:00488782920.018
hormone transportGO:00099141210.018
agingGO:00075682410.018
regulation of catabolic processGO:00098941130.018
Human
immune responseGO:00069551040.018
positive regulation of intracellular signal transductionGO:19025331380.018
response to vitaminGO:00332731310.018
g protein coupled receptor signaling pathwayGO:00071862420.017
sex differentiationGO:00075481130.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
regulation of nervous system developmentGO:00519602640.017
regulation of protein phosphorylationGO:00019321830.017
Human
positive regulation of apoptotic processGO:00430651540.017
carboxylic acid transportGO:00469421150.017
cellular response to organic cyclic compoundGO:00714072020.017
regulation of cell differentiationGO:00455953200.017
regulation of nucleotide metabolic processGO:00061401170.017
organophosphate biosynthetic processGO:00904071430.017
circulatory system processGO:00030131830.017
cellular nitrogen compound catabolic processGO:00442701630.017
circulatory system developmentGO:00723591340.017
blood circulationGO:00080151830.017
vesicle mediated transportGO:00161921810.017
cellular ion homeostasisGO:00068731840.017
muscle structure developmentGO:0061061870.016
negative regulation of multicellular organismal processGO:00512412030.016
cellular macromolecule localizationGO:00707271220.016
positive regulation of programmed cell deathGO:00430681570.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
growthGO:00400071650.016
protein complex assemblyGO:00064612630.016
negative regulation of cellular protein metabolic processGO:00322691060.016
Human
developmental growthGO:00485891000.016
gland developmentGO:00487321550.016
cell growthGO:00160491040.016
negative regulation of catalytic activityGO:00430861030.016
Human
positive regulation of macromolecule biosynthetic processGO:00105572470.016
single organism carbohydrate metabolic processGO:00447231180.016
Human
negative regulation of transportGO:00510511360.016
macromolecule catabolic processGO:0009057580.016
Human
positive regulation of transferase activityGO:0051347810.016
Human
glycerolipid metabolic processGO:0046486670.015
nucleobase containing small molecule metabolic processGO:00550863160.015
organelle organizationGO:00069962660.015
Human
cellular cation homeostasisGO:00300031800.015
mapk cascadeGO:00001651400.015
ribonucleoside triphosphate catabolic processGO:00092031220.015
hepaticobiliary system developmentGO:0061008900.015
protein oligomerizationGO:00512591910.015
organophosphate metabolic processGO:00196373700.015
positive regulation of nucleotide catabolic processGO:0030813530.015
response to ketoneGO:19016541820.015
aromatic compound catabolic processGO:00194391680.015
carbohydrate derivative metabolic processGO:19011353460.015
regulation of metal ion transportGO:00109591180.015
regulation of anatomical structure morphogenesisGO:00226031410.015
cation homeostasisGO:00550801950.015
glycosyl compound metabolic processGO:19016571820.015
single organism biosynthetic processGO:00447113420.015
regulation of hydrolase activityGO:00513361430.014
cellular amine metabolic processGO:0044106380.014
negative regulation of macromolecule biosynthetic processGO:00105581480.014
cellular response to lipidGO:00713962010.014
regulation of stress activated protein kinase signaling cascadeGO:0070302230.014
protein modification by small protein conjugation or removalGO:0070647350.014
Human
cytoplasmic transportGO:00164821150.014
response to oxygen levelsGO:00704822650.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
positive regulation of mapk cascadeGO:0043410920.014
cellular response to peptideGO:19016531330.014
positive regulation of secretionGO:00510471400.014
gamete generationGO:00072761240.014
positive regulation of catalytic activityGO:00430851840.014
Human
purine nucleotide catabolic processGO:00061951360.014
regulation of intracellular signal transductionGO:19025312180.014
Human
ras protein signal transductionGO:0007265290.014
cell projection organizationGO:00300303020.014
protein complex subunit organizationGO:00718223020.014
response to acid chemicalGO:00011012220.014
response to estradiolGO:00323551640.013
regulation of cell growthGO:0001558850.013
regulation of vesicle mediated transportGO:0060627810.013
development of primary sexual characteristicsGO:00451371070.013
regulation of nucleotide catabolic processGO:0030811650.013
nucleoside metabolic processGO:00091161790.013
positive regulation of catabolic processGO:0009896780.013
Human
regulation of amine transportGO:0051952540.013
protein transportGO:00150311320.013
inorganic ion transmembrane transportGO:00986602290.013
response to carbohydrateGO:00097431830.013
muscle system processGO:00030121150.013
purine nucleoside catabolic processGO:00061521240.013
cytokine productionGO:0001816610.013
cellular metal ion homeostasisGO:00068751720.013
amide transportGO:00428861050.013
positive regulation of response to stimulusGO:00485842850.013
monovalent inorganic cation transportGO:00156721720.013
cellular component movementGO:00069282480.013
Human
membrane organizationGO:0061024940.013
protein localizationGO:00081041910.013
response to hypoxiaGO:00016662310.013
negative regulation of cell differentiationGO:0045596990.013
response to mechanical stimulusGO:00096121340.013
response to metal ionGO:00100382530.013
negative regulation of cellular component organizationGO:0051129830.013
response to decreased oxygen levelsGO:00362932370.013
syncytium formation by plasma membrane fusionGO:000076830.012
organic anion transportGO:00157111320.012
negative regulation of response to stimulusGO:00485851550.012
Human
regulation of ion transmembrane transportGO:00347651210.012
nucleoside phosphate metabolic processGO:00067532830.012
negative regulation of neurogenesisGO:0050768780.012
peptidyl tyrosine modificationGO:0018212720.012
neuron projection morphogenesisGO:00488121220.012
small gtpase mediated signal transductionGO:0007264360.012
organic acid transportGO:00158491160.012
cellular component morphogenesisGO:00329891550.012
regulation of cell developmentGO:00602842630.012
protein modification by small protein conjugationGO:0032446310.012
Human
nucleoside triphosphate catabolic processGO:00091431230.012
stress activated mapk cascadeGO:0051403350.012
hormone secretionGO:00468791150.012
positive regulation of protein phosphorylationGO:00019341350.012
regulation of purine nucleotide catabolic processGO:0033121650.012
regulation of anion transportGO:0044070430.012
calcium ion homeostasisGO:00550741620.012
neuron projection developmentGO:00311752730.012
regulation of hormone secretionGO:00468831060.012
synaptic growth at neuromuscular junctionGO:005112410.012
male gamete generationGO:0048232990.012
response to ammonium ionGO:0060359710.012
positive regulation of purine nucleotide catabolic processGO:0033123530.012
regulation of transmembrane transportGO:00347621220.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
inflammatory responseGO:00069541500.012
asymmetric protein localizationGO:000810520.012
rho protein signal transductionGO:0007266110.012
negative regulation of organ growthGO:004662130.012
regulation of neurogenesisGO:00507672470.012
lipid transportGO:0006869610.012
regulation of neuron projection developmentGO:00109751610.012
carbohydrate metabolic processGO:00059751300.012
Human
localization of cellGO:00516742020.012
Human
regulation of establishment of protein localizationGO:0070201690.011
negative regulation of cell deathGO:00605482290.011
positive regulation of cellular catabolic processGO:0031331710.011
Human
female pregnancyGO:00075651220.011
positive regulation of purine nucleotide metabolic processGO:1900544910.011
regenerationGO:00310991630.011
regulation of cellular response to stressGO:0080135490.011
signal releaseGO:00230611450.011
protein ubiquitinationGO:0016567280.011
Human
regulation of nucleoside metabolic processGO:0009118660.011
negative regulation of intracellular signal transductionGO:1902532380.011
Human
regulation of smooth muscle cell proliferationGO:0048660750.011
negative regulation of developmental processGO:00510931250.011
response to glucoseGO:00097491360.011
positive regulation of cellular amine metabolic processGO:003324030.011
b cell differentiationGO:003018320.011
positive regulation of transcription dna templatedGO:00458931970.011
purine containing compound catabolic processGO:00725231380.011
cytoskeleton organizationGO:00070101110.011
single organism intracellular transportGO:19025821660.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
peptide hormone secretionGO:0030072840.011
multicellular organism growthGO:003526410.011
response to molecule of bacterial originGO:00022371940.011
regulation of cellular component biogenesisGO:0044087860.011
Human
cell morphogenesis involved in differentiationGO:00009041190.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
biological adhesionGO:00226101100.011
Human
positive regulation of growthGO:0045927550.011
cofactor metabolic processGO:0051186950.011
liver developmentGO:0001889900.011
positive regulation of cell differentiationGO:00455972170.011
reproductive system developmentGO:00614581280.011
peptide secretionGO:0002790860.011
positive regulation of secretion by cellGO:19035321280.011
locomotor rhythmGO:004547510.011
cardiovascular system developmentGO:00723581340.010
nucleoside phosphate catabolic processGO:19012921400.010
negative regulation of secretion by cellGO:1903531720.010
spermatogenesisGO:0007283990.010
regulation of system processGO:00440572080.010
response to oxidative stressGO:00069791860.010
positive regulation of cell developmentGO:00107201760.010
organonitrogen compound catabolic processGO:19015651790.010
regulation of ion transmembrane transporter activityGO:0032412480.010
regulation of mrna splicing via spliceosomeGO:004802430.010
purine nucleotide metabolic processGO:00061632290.010
nuclear transportGO:0051169490.010
regulation of actin cytoskeleton organizationGO:0032956300.010
cellular macromolecule catabolic processGO:0044265290.010
Human
regulation of cellular component movementGO:00512701500.010
Human
negative regulation of secretionGO:0051048820.010
jnk cascadeGO:0007254280.010
regulation of cytoskeleton organizationGO:0051493490.010

Pten disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org