Rattus norvegicus

15 known processes

Arfgef2

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)

(Aliases: Big2)

Arfgef2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular protein metabolic processGO:00322682670.107
rna metabolic processGO:00160704060.105
intracellular signal transductionGO:00355563140.081
Human
rna biosynthetic processGO:00327743800.074
regulation of signal transductionGO:00099663180.073
catabolic processGO:00090563510.073
Human
cellular response to endogenous stimulusGO:00714953770.068
response to extracellular stimulusGO:00099913800.068
protein complex assemblyGO:00064612630.068
regulation of rna metabolic processGO:00512523910.068
regulation of rna biosynthetic processGO:20011413810.065
macromolecular complex assemblyGO:00650032730.063
macromolecular complex subunit organizationGO:00439333390.062
organophosphate metabolic processGO:00196373700.060
Human
nucleoside phosphate metabolic processGO:00067532830.059
Human
regulation of transcription dna templatedGO:00063553740.056
response to nutrient levelsGO:00316673700.055
regulation of cell proliferationGO:00421273590.055
protein complex subunit organizationGO:00718223020.054
positive regulation of nitrogen compound metabolic processGO:00511733340.053
Human
programmed cell deathGO:00125013920.052
secretion by cellGO:00329402480.052
regulation of programmed cell deathGO:00430673410.052
transcription dna templatedGO:00063513770.052
head developmentGO:00603222470.051
nucleic acid templated transcriptionGO:00976593790.051
anatomical structure morphogenesisGO:00096532980.049
regulation of protein metabolic processGO:00512462890.049
regulation of phosphate metabolic processGO:00192203490.049
Human
vesicle mediated transportGO:00161921810.048
response to nutrientGO:00075842480.047
single organism catabolic processGO:00447122830.047
Human
regulation of apoptotic processGO:00429813350.047
regulation of protein modification processGO:00313991940.047
negative regulation of metabolic processGO:00098923310.046
regulation of phosphorylationGO:00423252480.046
cellular response to nitrogen compoundGO:19016992100.045
positive regulation of phosphate metabolic processGO:00459372620.044
Human
central nervous system developmentGO:00074173110.044
homeostatic processGO:00425923310.043
apoptotic processGO:00069153810.043
regulation of secretionGO:00510462240.042
organelle organizationGO:00069962660.042
Human
cellular response to organonitrogen compoundGO:00714171970.042
cell cell signalingGO:00072673350.042
regulation of nucleic acid templated transcriptionGO:19035063800.042
positive regulation of multicellular organismal processGO:00512403870.040
Human
organic acid metabolic processGO:00060822920.040
regulation of intracellular signal transductionGO:19025312180.040
positive regulation of rna metabolic processGO:00512542030.040
cellular catabolic processGO:00442482950.040
Human
ribonucleotide metabolic processGO:00092592310.040
Human
positive regulation of developmental processGO:00510942830.039
regulation of catalytic activityGO:00507903040.039
Human
positive regulation of cellular biosynthetic processGO:00313282950.039
cellular response to oxygen containing compoundGO:19017013860.039
single organism intracellular transportGO:19025821660.038
Human
chemical homeostasisGO:00488782920.037
multi organism reproductive processGO:00447032620.037
purine ribonucleotide metabolic processGO:00091502270.036
Human
brain developmentGO:00074202470.036
negative regulation of macromolecule metabolic processGO:00106052600.035
multicellular organismal reproductive processGO:00486092330.035
oxoacid metabolic processGO:00434362900.035
cellular response to stressGO:00335542690.034
reproductive processGO:00224143720.034
regulation of cellular component organizationGO:00511283680.034
lipid metabolic processGO:00066292830.033
nucleotide metabolic processGO:00091172790.033
Human
single organism reproductive processGO:00447022970.033
positive regulation of biosynthetic processGO:00098913190.033
macromolecule localizationGO:00330362520.032
carbohydrate derivative metabolic processGO:19011353460.032
Human
organic substance catabolic processGO:19015753160.032
Human
positive regulation of gene expressionGO:00106282440.032
regulation of multicellular organismal developmentGO:20000263760.032
single organism biosynthetic processGO:00447113420.032
secretionGO:00469033070.031
cellular component biogenesisGO:00440853680.031
response to inorganic substanceGO:00100353770.031
tissue developmentGO:00098882520.030
reproductionGO:00000032450.030
positive regulation of nervous system developmentGO:00519621780.030
regulation of cell differentiationGO:00455953200.030
regulation of molecular functionGO:00650093980.030
Human
carboxylic acid metabolic processGO:00197522890.030
protein complex biogenesisGO:00702712630.030
regulation of phosphorus metabolic processGO:00511743490.030
Human
positive regulation of transcription dna templatedGO:00458931970.030
positive regulation of nucleic acid templated transcriptionGO:19035081970.030
regulation of secretion by cellGO:19035302080.029
protein localizationGO:00081041910.029
multicellular organism reproductionGO:00325042330.029
response to growth factorGO:00708481890.029
cellular component assemblyGO:00226073600.029
response to peptideGO:19016522920.029
transmembrane transportGO:00550854120.029
positive regulation of cellular component organizationGO:00511302000.028
purine nucleotide metabolic processGO:00061632290.028
Human
regulation of canonical wnt signaling pathwayGO:006082840.028
negative regulation of cell communicationGO:00106481580.028
cellular response to hormone stimulusGO:00328702470.028
positive regulation of nucleobase containing compound metabolic processGO:00459353190.028
Human
purine containing compound metabolic processGO:00725212530.028
Human
positive regulation of cell differentiationGO:00455972170.028
cellular ketone metabolic processGO:0042180510.028
regulation of neuron differentiationGO:00456642080.027
nucleobase containing small molecule metabolic processGO:00550863160.027
Human
rhythmic processGO:00485111560.027
regulation of nervous system developmentGO:00519602640.027
neuron developmentGO:00486662860.027
lipid biosynthetic processGO:00086101280.027
positive regulation of phosphorus metabolic processGO:00105622620.027
Human
cellular amino acid metabolic processGO:00065201070.027
organonitrogen compound catabolic processGO:19015651790.027
Human
cation transmembrane transportGO:00986552630.026
positive regulation of neurogenesisGO:00507691650.026
positive regulation of cell proliferationGO:00082842490.026
negative regulation of protein metabolic processGO:00512481140.026
negative regulation of signalingGO:00230571570.025
ribose phosphate metabolic processGO:00196932350.025
Human
neuron differentiationGO:00301823680.025
negative regulation of programmed cell deathGO:00430691830.025
response to peptide hormoneGO:00434342780.025
purine nucleoside triphosphate metabolic processGO:00091441410.025
Human
chromosome segregationGO:000705920.025
negative regulation of gene expressionGO:00106291990.025
cellular response to growth factor stimulusGO:00713631620.025
purine nucleoside metabolic processGO:00422781690.024
Human
regulation of neurogenesisGO:00507672470.024
positive regulation of cell developmentGO:00107201760.024
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.024
regulation of cellular localizationGO:00603412630.024
positive regulation of macromolecule biosynthetic processGO:00105572470.024
cellular homeostasisGO:00197252520.024
regulation of system processGO:00440572080.024
negative regulation of response to stimulusGO:00485851550.023
agingGO:00075682410.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
regulation of response to stressGO:00801341260.023
negative regulation of cellular metabolic processGO:00313242810.023
negative regulation of apoptotic processGO:00430661810.023
positive regulation of cellular protein metabolic processGO:00322701670.023
cellular macromolecule localizationGO:00707271220.022
negative regulation of molecular functionGO:00440921330.022
lipid localizationGO:0010876620.022
cofactor metabolic processGO:0051186950.022
ion transmembrane transportGO:00342203650.022
transcription from rna polymerase ii promoterGO:00063662520.022
cellular response to peptide hormone stimulusGO:00713751200.022
regulation of membrane potentialGO:00423911100.022
intracellular transportGO:00469071850.022
Human
protein oligomerizationGO:00512591910.022
regulation of proteasomal protein catabolic processGO:006113640.022
behaviorGO:00076102050.022
regulation of cell developmentGO:00602842630.022
purine ribonucleoside metabolic processGO:00461281680.021
Human
ion homeostasisGO:00508012120.021
positive regulation of rna biosynthetic processGO:19026801970.021
neurological system processGO:00508772190.021
regulation of anatomical structure morphogenesisGO:00226031410.021
cellular amine metabolic processGO:0044106380.021
amine metabolic processGO:0009308380.021
positive regulation of catabolic processGO:0009896780.021
Human
enzyme linked receptor protein signaling pathwayGO:00071671160.021
nucleoside metabolic processGO:00091161790.021
Human
negative regulation of cellular protein metabolic processGO:00322691060.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.020
cation transportGO:00068123820.020
protein phosphorylationGO:00064683450.020
negative regulation of cell deathGO:00605482290.020
response to woundingGO:00096112540.020
regulation of cellular ketone metabolic processGO:0010565270.020
cellular lipid metabolic processGO:00442552080.020
regulation of immune system processGO:00026821230.020
regulation of protein phosphorylationGO:00019321830.020
proteolysisGO:00065081750.020
positive regulation of protein metabolic processGO:00512471780.019
cellular chemical homeostasisGO:00550822470.019
positive regulation of signalingGO:00230562700.019
anion transportGO:00068201780.019
regulation of cellular catabolic processGO:00313291010.019
Human
cellular protein localizationGO:00346131220.019
hormone secretionGO:00468791150.019
response to oxidative stressGO:00069791860.019
hormone transportGO:00099141210.019
purine nucleotide catabolic processGO:00061951360.018
Human
neuron projection developmentGO:00311752730.018
developmental process involved in reproductionGO:00030061590.018
positive regulation of neuron differentiationGO:00456661260.018
purine nucleoside triphosphate catabolic processGO:00091461220.018
Human
transmission of nerve impulseGO:0019226420.018
response to metal ionGO:00100382530.018
carbohydrate derivative catabolic processGO:19011361470.018
Human
organophosphate catabolic processGO:00464341480.018
Human
locomotionGO:00400112370.018
regulation of catabolic processGO:00098941130.018
Human
coenzyme metabolic processGO:0006732860.018
cell projection organizationGO:00300303020.017
regulation of body fluid levelsGO:0050878900.017
growthGO:00400071650.017
positive regulation of transportGO:00510502450.017
gamete generationGO:00072761240.017
multicellular organism growthGO:003526410.017
negative regulation of nitrogen compound metabolic processGO:00511721610.017
inorganic cation transmembrane transportGO:00986622020.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
ribonucleoside triphosphate catabolic processGO:00092031220.017
Human
positive regulation of neuron projection developmentGO:0010976990.017
single organism organelle organizationGO:19025891800.017
cytoplasmic transportGO:00164821150.017
Human
response to decreased oxygen levelsGO:00362932370.017
metal ion transportGO:00300012890.016
negative regulation of rna metabolic processGO:00512531230.016
circulatory system processGO:00030131830.016
axis specificationGO:000979840.016
cellular nitrogen compound catabolic processGO:00442701630.016
Human
nucleotide catabolic processGO:00091661390.016
Human
positive regulation of phosphorylationGO:00423271770.016
response to ketoneGO:19016541820.016
cellular response to organic cyclic compoundGO:00714072020.016
protein autophosphorylationGO:0046777660.016
regulation of cellular amino acid metabolic processGO:000652120.016
purine containing compound catabolic processGO:00725231380.016
Human
purine nucleoside catabolic processGO:00061521240.015
Human
negative regulation of signal transductionGO:0009968830.015
organic cyclic compound catabolic processGO:19013611750.015
Human
inorganic ion transmembrane transportGO:00986602290.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
nucleoside catabolic processGO:00091641260.015
Human
multicellular organismal signalingGO:0035637440.015
regulation of cell morphogenesisGO:0022604770.015
glycosyl compound metabolic processGO:19016571820.015
Human
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
Human
heterocycle catabolic processGO:00467001670.015
Human
nucleoside phosphate catabolic processGO:19012921400.015
Human
protein heterooligomerizationGO:0051291890.015
synaptic transmissionGO:00072682350.015
small gtpase mediated signal transductionGO:0007264360.015
regulation of cellular amine metabolic processGO:003323880.015
ribonucleoside metabolic processGO:00091191740.015
Human
sexual reproductionGO:00199531480.015
ribonucleotide catabolic processGO:00092611360.015
Human
negative regulation of multicellular organismal processGO:00512412030.015
neuronal action potentialGO:0019228350.015
regulation of purine nucleotide metabolic processGO:19005421150.015
Human
nitrogen compound transportGO:00717052290.015
protein transportGO:00150311320.015
regulation of neuron projection developmentGO:00109751610.015
positive regulation of protein modification processGO:00314011420.015
lipid transportGO:0006869610.014
ribonucleoside triphosphate metabolic processGO:00091991410.014
Human
negative regulation of biosynthetic processGO:00098901680.014
regulation of cell growthGO:0001558850.014
oxidation reduction processGO:00551143040.014
establishment of protein localizationGO:00451841410.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
response to vitaminGO:00332731310.014
cellular component movementGO:00069282480.014
nucleoside monophosphate metabolic processGO:0009123930.014
cellular cation homeostasisGO:00300031800.014
response to biotic stimulusGO:00096072260.014
nucleoside phosphate biosynthetic processGO:19012931020.014
ribonucleoside catabolic processGO:00424541260.014
Human
immune system processGO:00023762040.014
positive regulation of response to stimulusGO:00485842850.014
regulation of defense responseGO:0031347680.014
regulation of growthGO:00400081050.014
acylglycerol metabolic processGO:0006639210.014
response to oxygen levelsGO:00704822650.014
cellular response to external stimulusGO:00714961180.014
organophosphate biosynthetic processGO:00904071430.014
positive regulation of molecular functionGO:00440932300.014
Human
negative regulation of transportGO:00510511360.014
action potentialGO:0001508540.014
blood circulationGO:00080151830.014
spermatogenesisGO:0007283990.014
cellular response to peptideGO:19016531330.014
regulation of response to external stimulusGO:00321011060.014
positive regulation of nucleotide metabolic processGO:0045981910.013
Human
spindle organizationGO:000705120.013
organonitrogen compound biosynthetic processGO:19015661670.013
purine ribonucleoside triphosphate catabolic processGO:00092071220.013
Human
ras protein signal transductionGO:0007265290.013
cell motilityGO:00488702020.013
purine ribonucleoside catabolic processGO:00461301240.013
Human
ribonucleoside monophosphate metabolic processGO:0009161880.013
monocarboxylic acid metabolic processGO:00327871520.013
male gamete generationGO:0048232990.013
negative regulation of transcription dna templatedGO:00458921160.013
defense responseGO:00069521940.013
regulation of hydrolase activityGO:00513361430.013
Human
regulation of cell projection organizationGO:00313441750.013
response to radiationGO:00093141370.013
nucleobase containing compound catabolic processGO:00346551520.013
Human
dna metabolic processGO:0006259960.013
response to hypoxiaGO:00016662310.013
signal releaseGO:00230611450.013
negative regulation of intracellular signal transductionGO:1902532380.013
lipid storageGO:001991510.013
dephosphorylationGO:0016311980.013
response to insulinGO:00328681330.013
organic anion transportGO:00157111320.013
positive regulation of protein phosphorylationGO:00019341350.013
cell growthGO:00160491040.013
response to estrogenGO:00436272320.013
development of primary sexual characteristicsGO:00451371070.012
regulation of protein kinase activityGO:00458591050.012
regulation of anatomical structure sizeGO:00900661350.012
response to reactive oxygen speciesGO:00003021200.012
gastrulationGO:000736920.012
negative regulation of catalytic activityGO:00430861030.012
developmental growthGO:00485891000.012
nucleotide biosynthetic processGO:0009165980.012
cellular ion homeostasisGO:00068731840.012
glycerolipid metabolic processGO:0046486670.012
response to carbohydrateGO:00097431830.012
regulation of transferase activityGO:00513381230.012
positive regulation of cellular amine metabolic processGO:003324030.012
atp metabolic processGO:0046034720.012
alpha amino acid metabolic processGO:1901605710.012
positive regulation of purine nucleotide metabolic processGO:1900544910.012
Human
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
glycosyl compound catabolic processGO:19016581260.012
Human
aromatic compound catabolic processGO:00194391680.012
Human
positive regulation of signal transductionGO:00099671750.012
gonad developmentGO:00084061040.012
endocytosisGO:0006897840.012
sex differentiationGO:00075481130.012
embryonic pattern specificationGO:000988010.012
regulation of hormone secretionGO:00468831060.012
regulation of developmental growthGO:0048638450.012
positive regulation of cell projection organizationGO:00313461110.012
response to glucoseGO:00097491360.012
metal ion homeostasisGO:00550651860.012
cell morphogenesisGO:00009021420.012
carboxylic acid transportGO:00469421150.012
cellular component morphogenesisGO:00329891550.012
ribonucleotide biosynthetic processGO:0009260850.012
actin filament based processGO:0030029860.011
posttranscriptional regulation of gene expressionGO:0010608370.011
cytoskeleton organizationGO:00070101110.011
single organism cellular localizationGO:19025801020.011
monovalent inorganic cation transportGO:00156721720.011
regulation of hormone levelsGO:00108171870.011
maintenance of locationGO:0051235170.011
negative regulation of rna biosynthetic processGO:19026791180.011
positive regulation of catalytic activityGO:00430851840.011
Human
hormone metabolic processGO:0042445690.011
forebrain developmentGO:0030900980.011
eye morphogenesisGO:004859240.011
positive regulation of lipid catabolic processGO:005099640.011
purine ribonucleotide catabolic processGO:00091541360.011
Human
regulation of cell morphogenesis involved in differentiationGO:0010769720.011
positive regulation of secretionGO:00510471400.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
g protein coupled receptor signaling pathwayGO:00071862420.011
peptide biosynthetic processGO:004304330.011
positive regulation of proteasomal protein catabolic processGO:190180030.011
single organism behaviorGO:00447081300.011
macroautophagyGO:001623640.011
gland developmentGO:00487321550.010
mesoderm developmentGO:000749820.010
nucleoside triphosphate catabolic processGO:00091431230.010
Human
carbohydrate metabolic processGO:00059751300.010
regulation of nucleotide metabolic processGO:00061401170.010
Human
protein modification by small protein conjugation or removalGO:0070647350.010
cellular response to cytokine stimulusGO:00713451270.010
cell migrationGO:00164771970.010
response to hexoseGO:00097461440.010
response to monosaccharideGO:00342841590.010
protein homooligomerizationGO:0051260910.010
neutral lipid metabolic processGO:0006638210.010
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.010
peptidyl tyrosine modificationGO:0018212720.010
purine nucleoside monophosphate catabolic processGO:0009128550.010
actin cytoskeleton organizationGO:0030036730.010
ribose phosphate biosynthetic processGO:0046390870.010

Arfgef2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.033
nervous system diseaseDOID:86300.033
musculoskeletal system diseaseDOID:1700.021
sensory system diseaseDOID:005015500.015
muscle tissue diseaseDOID:6600.015
muscular diseaseDOID:008000000.015
disease of metabolismDOID:001466700.014
eye and adnexa diseaseDOID:149200.011
eye diseaseDOID:561400.011
central nervous system diseaseDOID:33100.011