Rattus norvegicus

22 known processes

Fh1

fumarate hydratase 1

(Aliases: Fh,MGC105468)

Fh1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
coenzyme metabolic processGO:0006732860.816
dicarboxylic acid metabolic processGO:0043648420.741
glycosyl compound metabolic processGO:19016571820.585
generation of precursor metabolites and energyGO:0006091620.568
cofactor metabolic processGO:0051186950.533
purine nucleoside monophosphate metabolic processGO:0009126840.513
oxidation reduction processGO:00551143040.501
oxidative phosphorylationGO:000611940.474
atp metabolic processGO:0046034720.471
cellular respirationGO:0045333210.457
citrate metabolic processGO:000610130.448
oxoacid metabolic processGO:00434362900.443
aerobic respirationGO:0009060130.437
nucleobase containing small molecule metabolic processGO:00550863160.409
ribonucleoside monophosphate metabolic processGO:0009161880.364
nucleoside phosphate metabolic processGO:00067532830.342
nucleoside monophosphate metabolic processGO:0009123930.331
carboxylic acid metabolic processGO:00197522890.329
organic acid metabolic processGO:00060822920.318
purine containing compound metabolic processGO:00725212530.278
nucleotide metabolic processGO:00091172790.266
tricarboxylic acid metabolic processGO:0072350100.236
nucleoside metabolic processGO:00091161790.228
nicotinamide nucleotide metabolic processGO:0046496280.220
tricarboxylic acid cycleGO:0006099110.220
electron transport chainGO:002290050.214
purine ribonucleoside triphosphate metabolic processGO:00092051400.204
purine nucleoside metabolic processGO:00422781690.197
purine nucleotide metabolic processGO:00061632290.189
ribonucleoside metabolic processGO:00091191740.165
organelle organizationGO:00069962660.165
mitochondrion organizationGO:0007005350.152
purine ribonucleoside metabolic processGO:00461281680.152
cofactor biosynthetic processGO:0051188280.150
carbohydrate derivative metabolic processGO:19011353460.147
ribonucleoside triphosphate metabolic processGO:00091991410.133
isocitrate metabolic processGO:000610250.132
nucleoside triphosphate metabolic processGO:00091411440.126
ribonucleotide metabolic processGO:00092592310.123
growthGO:00400071650.115
nadh metabolic processGO:0006734100.112
purine ribonucleoside monophosphate metabolic processGO:0009167840.110
organophosphate metabolic processGO:00196373700.099
single organism biosynthetic processGO:00447113420.098
tetrapyrrole metabolic processGO:0033013110.096
nad metabolic processGO:0019674150.094
transmembrane transportGO:00550854120.092
purine ribonucleotide metabolic processGO:00091502270.090
organic substance catabolic processGO:19015753160.081
energy derivation by oxidation of organic compoundsGO:0015980460.077
protein maturationGO:0051604680.076
atp synthesis coupled electron transportGO:004277320.075
oxidoreduction coenzyme metabolic processGO:0006733310.075
protein transportGO:00150311320.064
apoptotic mitochondrial changesGO:0008637100.062
single organism catabolic processGO:00447122830.059
purine nucleoside triphosphate metabolic processGO:00091441410.059
connective tissue developmentGO:0061448330.057
acyl coa metabolic processGO:0006637280.048
regulation of molecular functionGO:00650093980.044
purine nucleoside biosynthetic processGO:0042451210.044
reproductive processGO:00224143720.043
response to nutrient levelsGO:00316673700.041
ribonucleoside biosynthetic processGO:0042455250.041
single organism organelle organizationGO:19025891800.040
positive regulation of molecular functionGO:00440932300.040
regulation of apoptotic processGO:00429813350.040
sulfur compound metabolic processGO:0006790700.039
protein complex assemblyGO:00064612630.039
organonitrogen compound catabolic processGO:19015651790.037
vesicle mediated transportGO:00161921810.037
catabolic processGO:00090563510.035
nucleotide biosynthetic processGO:0009165980.035
regulation of membrane potentialGO:00423911100.034
nucleotide catabolic processGO:00091661390.033
response to extracellular stimulusGO:00099913800.033
cellular catabolic processGO:00442482950.033
intracellular transportGO:00469071850.032
negative regulation of programmed cell deathGO:00430691830.032
hepaticobiliary system developmentGO:0061008900.031
2 oxoglutarate metabolic processGO:000610360.031
cellular component biogenesisGO:00440853680.031
pyridine nucleotide metabolic processGO:0019362280.030
developmental process involved in reproductionGO:00030061590.030
liver developmentGO:0001889900.029
regulation of transferase activityGO:00513381230.029
programmed cell deathGO:00125013920.029
cellular component assemblyGO:00226073600.029
metanephric tubule developmentGO:007217040.028
protein oligomerizationGO:00512591910.027
regulation of signal transductionGO:00099663180.027
response to ethanolGO:00454711620.027
agingGO:00075682410.027
ribonucleotide biosynthetic processGO:0009260850.026
anion transportGO:00068201780.026
homeostatic processGO:00425923310.026
protein processingGO:0016485680.026
purine containing compound biosynthetic processGO:0072522850.026
single organism reproductive processGO:00447022970.026
reproductionGO:00000032450.026
cell redox homeostasisGO:004545410.025
positive regulation of atp biosynthetic processGO:200117120.025
protein complex biogenesisGO:00702712630.025
regulation of growthGO:00400081050.024
chemical homeostasisGO:00488782920.024
central nervous system developmentGO:00074173110.024
synaptic transmissionGO:00072682350.024
reproductive structure developmentGO:00486081280.023
purine nucleotide biosynthetic processGO:0006164830.022
pyridine containing compound metabolic processGO:0072524320.022
response to decreased oxygen levelsGO:00362932370.021
purine nucleoside triphosphate catabolic processGO:00091461220.021
single organism intracellular transportGO:19025821660.021
endocytosisGO:0006897840.021
regulation of nucleic acid templated transcriptionGO:19035063800.021
purine ribonucleoside monophosphate biosynthetic processGO:0009168200.020
brain developmentGO:00074202470.020
ribose phosphate metabolic processGO:00196932350.020
response to toxic substanceGO:00096361330.020
response to external biotic stimulusGO:00432072210.020
apoptotic processGO:00069153810.019
purine nucleoside catabolic processGO:00061521240.019
cellular homeostasisGO:00197252520.019
response to oxygen levelsGO:00704822650.019
positive regulation of catalytic activityGO:00430851840.019
multicellular organism reproductionGO:00325042330.019
multicellular organismal reproductive processGO:00486092330.018
negative regulation of apoptotic processGO:00430661810.018
rna biosynthetic processGO:00327743800.018
response to tumor cellGO:000234740.018
regulation of phosphate metabolic processGO:00192203490.017
aromatic amino acid family metabolic processGO:000907290.017
mitochondrial transportGO:0006839190.017
regulation of hydrolase activityGO:00513361430.017
organic cyclic compound catabolic processGO:19013611750.017
cellular amino acid metabolic processGO:00065201070.017
immune system processGO:00023762040.017
negative regulation of cell communicationGO:00106481580.017
monocarboxylic acid metabolic processGO:00327871520.016
multi organism reproductive processGO:00447032620.016
cellular nitrogen compound catabolic processGO:00442701630.016
macromolecule localizationGO:00330362520.016
macromolecular complex assemblyGO:00650032730.016
behaviorGO:00076102050.016
gamete generationGO:00072761240.016
protein complex subunit organizationGO:00718223020.016
regulation of cellular component organizationGO:00511283680.016
purine ribonucleoside monophosphate catabolic processGO:0009169550.015
positive regulation of cell proliferationGO:00082842490.015
regulation of programmed cell deathGO:00430673410.015
skeletal system developmentGO:0001501410.015
purine nucleoside monophosphate biosynthetic processGO:0009127200.015
organophosphate catabolic processGO:00464341480.015
single organism cellular localizationGO:19025801020.015
negative regulation of metabolic processGO:00098923310.015
regulation of catalytic activityGO:00507903040.015
cellular response to lipidGO:00713962010.015
cellular metal ion homeostasisGO:00068751720.014
cell cell signalingGO:00072673350.014
cellular response to stressGO:00335542690.014
sexual reproductionGO:00199531480.014
negative regulation of cell deathGO:00605482290.014
negative regulation of cellular metabolic processGO:00313242810.014
nucleoside phosphate catabolic processGO:19012921400.014
protein targetingGO:0006605610.014
muscle system processGO:00030121150.014
response to bacteriumGO:00096172000.013
macromolecular complex subunit organizationGO:00439333390.013
somatic cell dna recombinationGO:001644420.013
response to ketoneGO:19016541820.013
positive regulation of hydrolase activityGO:0051345860.013
transcription dna templatedGO:00063513770.013
phagocytosisGO:0006909170.013
heme biosynthetic processGO:000678340.013
positive regulation of protein metabolic processGO:00512471780.013
cellular response to oxygen containing compoundGO:19017013860.013
regulation of kinase activityGO:00435491170.013
response to molecule of bacterial originGO:00022371940.012
positive regulation of immune system processGO:0002684900.012
multi multicellular organism processGO:00447061380.012
leukocyte proliferationGO:0070661290.012
negative regulation of protein modification by small protein conjugation or removalGO:190332140.012
rna metabolic processGO:00160704060.012
lipid storageGO:001991510.012
organophosphate biosynthetic processGO:00904071430.012
purine containing compound catabolic processGO:00725231380.012
positive regulation of cellular protein metabolic processGO:00322701670.012
cellular response to extracellular stimulusGO:0031668730.012
negative regulation of signalingGO:00230571570.012
ion transmembrane transportGO:00342203650.012
proteolysisGO:00065081750.011
aromatic compound catabolic processGO:00194391680.011
amino acid importGO:004309070.011
regulation of cell differentiationGO:00455953200.011
positive regulation of cell activationGO:0050867340.011
syncytium formation by plasma membrane fusionGO:000076830.011
organonitrogen compound biosynthetic processGO:19015661670.011
t cell activationGO:0042110290.011
metal ion transportGO:00300012890.011
head developmentGO:00603222470.011
positive regulation of nitrogen compound metabolic processGO:00511733340.011
nucleobase containing compound catabolic processGO:00346551520.011
cytoplasmic transportGO:00164821150.011
heterocycle catabolic processGO:00467001670.011
positive regulation of viral processGO:004852420.011
cation transportGO:00068123820.011
purine nucleotide catabolic processGO:00061951360.011
purine ribonucleotide catabolic processGO:00091541360.011
nucleoside monophosphate biosynthetic processGO:0009124280.010
nephron developmentGO:0072006220.010
cellular response to acid chemicalGO:0071229750.010
purine ribonucleoside triphosphate catabolic processGO:00092071220.010
ribonucleoside catabolic processGO:00424541260.010
spermatogenesisGO:0007283990.010
response to acid chemicalGO:00011012220.010
neurotransmitter uptakeGO:000150430.010
lymphocyte activationGO:0046649430.010
response to oxidative stressGO:00069791860.010
response to inorganic substanceGO:00100353770.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
regulation of peptidase activityGO:0052547550.010
cellular chemical homeostasisGO:00550822470.010
positive regulation of lymphocyte activationGO:0051251250.010

Fh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.164
disease of anatomical entityDOID:700.164
disease of metabolismDOID:001466700.053
inherited metabolic disorderDOID:65500.053
central nervous system diseaseDOID:33100.038
cancerDOID:16200.031
disease of cellular proliferationDOID:1456600.031
gastrointestinal system cancerDOID:311900.031
organ system cancerDOID:005068600.031
organic acidemiaDOID:006015900.030
maple syrup urine diseaseDOID:926900.030
amino acid metabolic disorderDOID:925200.030
sensory system diseaseDOID:005015500.017
retinal diseaseDOID:567900.015
eye diseaseDOID:561400.015
eye and adnexa diseaseDOID:149200.015
retinitis pigmentosaDOID:1058400.013
retinal degenerationDOID:846600.013