Rattus norvegicus

0 known processes

Espn

espin

(Aliases: Je)

Espn biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to metal ionGO:00100382530.320
positive regulation of nucleobase containing compound metabolic processGO:00459353190.231
behaviorGO:00076102050.201
Mouse
response to inorganic substanceGO:00100353770.168
positive regulation of amine transportGO:0051954260.127
brain developmentGO:00074202470.117
catabolic processGO:00090563510.114
reproductive processGO:00224143720.110
cellular lipid metabolic processGO:00442552080.100
cell projection morphogenesisGO:00488581230.099
regulation of cell proliferationGO:00421273590.097
cellular response to vitamin eGO:007130630.089
regulation of ion transportGO:00432692450.086
organic substance catabolic processGO:19015753160.085
cell growthGO:00160491040.085
positive regulation of nitrogen compound metabolic processGO:00511733340.085
cell morphogenesisGO:00009021420.084
fatty acid metabolic processGO:0006631990.083
locomotionGO:00400112370.083
rna metabolic processGO:00160704060.082
cellular component movementGO:00069282480.081
regulation of transcription dna templatedGO:00063553740.079
neuron projection developmentGO:00311752730.078
oxoacid metabolic processGO:00434362900.077
neuron differentiationGO:00301823680.077
axon developmentGO:0061564960.076
nucleotide metabolic processGO:00091172790.076
response to nutrient levelsGO:00316673700.075
monocarboxylic acid metabolic processGO:00327871520.074
response to oxygen levelsGO:00704822650.073
transmembrane transportGO:00550854120.073
nucleobase containing small molecule metabolic processGO:00550863160.072
ribonucleotide metabolic processGO:00092592310.071
oxidation reduction processGO:00551143040.071
cellular catabolic processGO:00442482950.071
regulation of locomotionGO:00400121480.070
transcription from rna polymerase ii promoterGO:00063662520.069
response to peptideGO:19016522920.069
cell morphogenesis involved in neuron differentiationGO:00486671060.067
cell part morphogenesisGO:00329901230.067
rhythmic processGO:00485111560.067
single organism biosynthetic processGO:00447113420.065
positive regulation of biosynthetic processGO:00098913190.065
cellular response to stressGO:00335542690.065
motor neuron axon guidanceGO:000804510.064
response to mineralocorticoidGO:0051385490.061
sensory organ developmentGO:0007423740.061
reproductive system developmentGO:00614581280.060
purine nucleotide metabolic processGO:00061632290.058
regulation of transcription from rna polymerase ii promoterGO:00063572340.058
neuron projection morphogenesisGO:00488121220.058
purine containing compound metabolic processGO:00725212530.057
organic acid metabolic processGO:00060822920.054
carbohydrate derivative catabolic processGO:19011361470.054
carboxylic acid metabolic processGO:00197522890.053
cellular component biogenesisGO:00440853680.053
Mouse
neurological system processGO:00508772190.053
head developmentGO:00603222470.053
negative regulation of developmental processGO:00510931250.052
reproductionGO:00000032450.052
positive regulation of rna biosynthetic processGO:19026801970.050
response to ammonium ionGO:0060359710.050
lipid metabolic processGO:00066292830.050
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.050
cation transportGO:00068123820.049
multi organism reproductive processGO:00447032620.049
regulation of rna metabolic processGO:00512523910.048
anatomical structure morphogenesisGO:00096532980.048
positive regulation of apoptotic processGO:00430651540.048
organic acid biosynthetic processGO:0016053830.048
central nervous system developmentGO:00074173110.047
regulation of molecular functionGO:00650093980.047
metal ion transportGO:00300012890.047
carbohydrate metabolic processGO:00059751300.046
single organism behaviorGO:00447081300.046
positive regulation of purine nucleotide metabolic processGO:1900544910.046
cellular response to acid chemicalGO:0071229750.046
apoptotic processGO:00069153810.045
ion transmembrane transportGO:00342203650.045
regulation of catalytic activityGO:00507903040.045
negative regulation of protein import into nucleus translocationGO:003315910.045
cyclic nucleotide metabolic processGO:0009187800.043
regulation of multicellular organismal developmentGO:20000263760.042
regulation of programmed cell deathGO:00430673410.042
single organism catabolic processGO:00447122830.042
positive regulation of cellular biosynthetic processGO:00313282950.042
negative regulation of macromolecule metabolic processGO:00106052600.042
multicellular organismal reproductive processGO:00486092330.041
cell morphogenesis involved in differentiationGO:00009041190.041
eye developmentGO:0001654500.041
regulation of blood vessel sizeGO:0050880890.041
regulation of purine nucleotide metabolic processGO:19005421150.041
positive regulation of cellular catabolic processGO:0031331710.041
regulation of nucleotide metabolic processGO:00061401170.040
regulation of cell growthGO:0001558850.040
cell projection organizationGO:00300303020.040
Mouse
lens fiber cell differentiationGO:007030630.040
positive regulation of gene expressionGO:00106282440.040
negative regulation of neurogenesisGO:0050768780.040
gastrulationGO:000736920.040
nucleoside phosphate metabolic processGO:00067532830.040
agingGO:00075682410.039
regulation of cellular ketone metabolic processGO:0010565270.039
heart developmentGO:0007507720.039
positive regulation of catabolic processGO:0009896780.038
ribonucleotide biosynthetic processGO:0009260850.038
inorganic ion transmembrane transportGO:00986602290.038
inorganic cation transmembrane transportGO:00986622020.038
response to acid chemicalGO:00011012220.038
sensory perceptionGO:00076001010.037
cellular component morphogenesisGO:00329891550.037
anion transportGO:00068201780.037
response to hypoxiaGO:00016662310.037
nucleoside metabolic processGO:00091161790.037
regulation of catabolic processGO:00098941130.037
carbohydrate derivative metabolic processGO:19011353460.037
negative regulation of nitrogen compound metabolic processGO:00511721610.035
cellular nitrogen compound catabolic processGO:00442701630.035
glucose metabolic processGO:0006006520.035
negative regulation of multicellular organismal processGO:00512412030.034
regulation of system processGO:00440572080.034
positive regulation of nucleic acid templated transcriptionGO:19035081970.034
positive regulation of nucleotide metabolic processGO:0045981910.034
positive regulation of transcription dna templatedGO:00458931970.033
developmental process involved in reproductionGO:00030061590.033
potassium ion transportGO:0006813970.033
g protein coupled receptor signaling pathwayGO:00071862420.033
negative regulation of nervous system developmentGO:0051961790.033
multi multicellular organism processGO:00447061380.033
lipid biosynthetic processGO:00086101280.032
macromolecular complex subunit organizationGO:00439333390.032
Mouse
response to corticosteroidGO:00319602350.032
regulation of cellular catabolic processGO:00313291010.032
purine nucleoside triphosphate catabolic processGO:00091461220.032
positive regulation of phosphorus metabolic processGO:00105622620.032
regulation of tube sizeGO:0035150890.031
response to monosaccharideGO:00342841590.031
response to cocaineGO:0042220390.030
ribonucleotide catabolic processGO:00092611360.030
organophosphate metabolic processGO:00196373700.030
multicellular organism reproductionGO:00325042330.030
negative regulation of cell proliferationGO:00082851190.030
regulation of nervous system developmentGO:00519602640.029
rna biosynthetic processGO:00327743800.029
mesoderm developmentGO:000749820.029
regulation of nucleic acid templated transcriptionGO:19035063800.029
nitrogen compound transportGO:00717052290.028
regulation of rna biosynthetic processGO:20011413810.028
glycosyl compound metabolic processGO:19016571820.028
small molecule biosynthetic processGO:00442831240.028
purine nucleoside catabolic processGO:00061521240.028
programmed cell deathGO:00125013920.028
purine ribonucleotide catabolic processGO:00091541360.028
sex differentiationGO:00075481130.027
hexose metabolic processGO:0019318580.027
dephosphorylationGO:0016311980.027
male gonad developmentGO:0008584590.027
positive regulation of macromolecule biosynthetic processGO:00105572470.027
response to peptide hormoneGO:00434342780.027
negative regulation of transcription regulatory region dna bindingGO:200067820.027
response to decreased oxygen levelsGO:00362932370.027
response to ethanolGO:00454711620.027
negative regulation of tyrosine phosphorylation of stat5 proteinGO:004252410.027
cellular response to oxygen containing compoundGO:19017013860.026
neuromuscular synaptic transmissionGO:000727420.026
organic cyclic compound catabolic processGO:19013611750.026
ribose phosphate metabolic processGO:00196932350.026
organonitrogen compound catabolic processGO:19015651790.026
fatty acid biosynthetic processGO:0006633330.026
negative regulation of molecular functionGO:00440921330.025
nucleotide biosynthetic processGO:0009165980.025
purine nucleotide catabolic processGO:00061951360.025
organic hydroxy compound metabolic processGO:19016151150.025
forebrain developmentGO:0030900980.025
intracellular signal transductionGO:00355563140.025
negative regulation of metabolic processGO:00098923310.025
positive regulation of molecular functionGO:00440932300.025
negative regulation of cellular metabolic processGO:00313242810.025
regulation of cellular component organizationGO:00511283680.025
Mouse
macromolecule localizationGO:00330362520.025
ribonucleoside metabolic processGO:00091191740.025
chemosensory behaviorGO:000763520.024
carboxylic acid biosynthetic processGO:0046394830.024
single organism intracellular transportGO:19025821660.024
reproductive structure developmentGO:00486081280.024
macromolecular complex assemblyGO:00650032730.024
regulation of neuron projection developmentGO:00109751610.024
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.024
regulation of fatty acid metabolic processGO:0019217180.024
organelle organizationGO:00069962660.024
Mouse
gonad developmentGO:00084061040.024
renal system processGO:0003014400.024
vascular process in circulatory systemGO:0003018960.024
synaptic transmissionGO:00072682350.024
purine ribonucleotide metabolic processGO:00091502270.024
cognitionGO:0050890920.024
response to nicotineGO:0035094510.024
positive regulation of rna metabolic processGO:00512542030.023
response to oxidative stressGO:00069791860.023
membrane organizationGO:0061024940.023
positive regulation of multicellular organismal processGO:00512403870.023
regulation of apoptotic processGO:00429813350.023
response to transition metal nanoparticleGO:19902671220.023
intracellular transportGO:00469071850.023
response to carbohydrateGO:00097431830.023
cellular ketone metabolic processGO:0042180510.023
gland developmentGO:00487321550.023
positive regulation of cell deathGO:00109421840.023
response to nutrientGO:00075842480.023
ribose phosphate biosynthetic processGO:0046390870.022
development of primary sexual characteristicsGO:00451371070.022
cellular component assemblyGO:00226073600.022
Mouse
male sex differentiationGO:0046661640.022
localization of cellGO:00516742020.022
growthGO:00400071650.022
dendrite morphogenesisGO:0048813430.022
dendrite developmentGO:0016358720.022
nucleotide catabolic processGO:00091661390.022
aromatic compound catabolic processGO:00194391680.022
lipid oxidationGO:0034440300.022
axonogenesisGO:0007409710.022
monocarboxylic acid biosynthetic processGO:0072330480.022
digestive tract developmentGO:0048565390.022
positive regulation of cellular component organizationGO:00511302000.022
Mouse
regulation of cell motilityGO:20001451310.022
cellular response to retinoic acidGO:0071300270.021
negative regulation of neuron differentiationGO:0045665620.021
regulation of anatomical structure sizeGO:00900661350.021
lipid storageGO:001991510.021
positive regulation of nucleotide catabolic processGO:0030813530.021
negative regulation of apoptotic processGO:00430661810.021
regulation of cell differentiationGO:00455953200.021
regulation of fat cell differentiationGO:004559830.021
vitamin a metabolic processGO:000677620.021
regulation of phosphate metabolic processGO:00192203490.021
purine ribonucleoside triphosphate catabolic processGO:00092071220.021
female pregnancyGO:00075651220.021
intracellular receptor signaling pathwayGO:0030522350.021
cellular homeostasisGO:00197252520.021
positive regulation of phosphate metabolic processGO:00459372620.020
ion homeostasisGO:00508012120.020
cellular response to gonadotropin stimulusGO:0071371170.020
purine ribonucleoside triphosphate metabolic processGO:00092051400.020
activation of jak2 kinase activityGO:004297720.020
positive regulation of signalingGO:00230562700.020
negative regulation of transcription dna templatedGO:00458921160.020
organophosphate catabolic processGO:00464341480.020
regulation of body fluid levelsGO:0050878900.020
amine metabolic processGO:0009308380.020
regulation of lipid metabolic processGO:0019216680.019
purine nucleoside triphosphate metabolic processGO:00091441410.019
response to vitamin aGO:0033189360.019
nucleoside triphosphate metabolic processGO:00091411440.019
intracellular protein transportGO:0006886790.019
transcription dna templatedGO:00063513770.019
anterior posterior pattern specificationGO:000995210.019
eye morphogenesisGO:004859240.019
carbohydrate derivative biosynthetic processGO:19011371240.019
regulation of cellular amine metabolic processGO:003323880.019
pancreatic stellate cell proliferationGO:007234320.019
monovalent inorganic cation transportGO:00156721720.019
cellular response to oxidative stressGO:0034599760.019
tissue developmentGO:00098882520.019
behavioral response to nicotineGO:003509520.019
negative regulation of cell differentiationGO:0045596990.018
purine ribonucleoside metabolic processGO:00461281680.018
organic anion transportGO:00157111320.018
single organism cellular localizationGO:19025801020.018
ribonucleoside catabolic processGO:00424541260.018
positive regulation of ion transportGO:0043270940.018
anion transmembrane transportGO:0098656770.018
negative regulation of cellular biosynthetic processGO:00313271610.018
regulation of cell developmentGO:00602842630.018
cell cell signalingGO:00072673350.018
circulatory system processGO:00030131830.018
protein complex assemblyGO:00064612630.017
development of primary male sexual characteristicsGO:0046546590.017
regulation of cell projection organizationGO:00313441750.017
Mouse
nucleoside phosphate catabolic processGO:19012921400.017
response to glucoseGO:00097491360.017
regulation of hormone levelsGO:00108171870.017
vitamin d receptor signaling pathwayGO:007056110.017
regulation of pancreatic stellate cell proliferationGO:200022920.017
response to mechanical stimulusGO:00096121340.017
regulation of neurogenesisGO:00507672470.017
response to woundingGO:00096112540.017
cyclic nucleotide biosynthetic processGO:0009190630.017
blood circulationGO:00080151830.017
nucleoside phosphate biosynthetic processGO:19012931020.016
positive regulation of fatty acid oxidationGO:004632160.016
negative regulation of cellular protein metabolic processGO:00322691060.016
cellular amine metabolic processGO:0044106380.016
developmental growthGO:00485891000.016
positive regulation of mitochondrion organizationGO:001082240.016
camera type eye morphogenesisGO:004859320.016
positive regulation of catalytic activityGO:00430851840.016
response to reactive oxygen speciesGO:00003021200.016
negative regulation of macromolecule biosynthetic processGO:00105581480.016
positive regulation of the force of heart contraction by norepinephrineGO:000306110.016
response to alkaloidGO:00432791320.016
negative regulation of sequence specific dna binding transcription factor activityGO:0043433110.016
negative regulation of biosynthetic processGO:00098901680.016
regulation of synaptic transmission glutamatergicGO:0051966260.016
nucleic acid templated transcriptionGO:00976593790.016
regulation of renal sodium excretionGO:0035813200.016
cellular glucan metabolic processGO:0006073230.016
positive regulation of cyclic nucleotide metabolic processGO:0030801370.016
heterocycle catabolic processGO:00467001670.016
cell motilityGO:00488702020.016
negative regulation of ion transportGO:0043271510.015
purine containing compound catabolic processGO:00725231380.015
regulation of cellular amino acid metabolic processGO:000652120.015
response to follicle stimulating hormoneGO:0032354180.015
entrainment of circadian clockGO:000964930.015
circadian rhythmGO:0007623880.015
s shaped body morphogenesisGO:007205020.015
regulation of gtpase activityGO:0043087570.015
regulation of g protein coupled receptor protein signaling pathwayGO:0008277280.015
purine ribonucleotide biosynthetic processGO:0009152810.015
nucleobase containing compound catabolic processGO:00346551520.015
negative regulation of rna metabolic processGO:00512531230.015
positive regulation of hydrolase activityGO:0051345860.015
response to hydrogen peroxideGO:0042542890.015
response to vitaminGO:00332731310.015
sensory perception of light stimulusGO:005095330.015
regenerationGO:00310991630.015
response to insulinGO:00328681330.015
unsaturated fatty acid metabolic processGO:0033559390.015
placenta developmentGO:0001890220.015
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.014
muscle system processGO:00030121150.014
sexual reproductionGO:00199531480.014
response to axon injuryGO:0048678590.014
response to calcium ionGO:0051592590.014
protein homooligomerizationGO:0051260910.014
olfactory behaviorGO:004204820.014
mapk cascadeGO:00001651400.014
regulation of ion transmembrane transportGO:00347651210.014
negative regulation of cell communicationGO:00106481580.014
regulation of neuron differentiationGO:00456642080.014
response to fatty acidGO:0070542650.014
negative regulation of nucleobase containing compound metabolic processGO:00459341530.014
monosaccharide metabolic processGO:0005996610.014
axis specificationGO:000979840.014
action potentialGO:0001508540.014
regulation of lipid biosynthetic processGO:0046890380.014
regulation of nucleotide catabolic processGO:0030811650.014
regulation of cellular component biogenesisGO:0044087860.014
Mouse
purine nucleoside metabolic processGO:00422781690.014
camera type eye developmentGO:0043010480.014
negative regulation of rna biosynthetic processGO:19026791180.013
organonitrogen compound biosynthetic processGO:19015661670.013
divalent metal ion transportGO:00708381320.013
regulation of growthGO:00400081050.013
heart contractionGO:0060047570.013
regulation of purine nucleotide catabolic processGO:0033121650.013
regulation of secretionGO:00510462240.013
ras protein signal transductionGO:0007265290.013
regulation of cyclic nucleotide biosynthetic processGO:0030802450.013
protein complex subunit organizationGO:00718223020.013
Mouse
axon choice point recognitionGO:001619820.013
regulation of vasodilationGO:0042312360.013
visual perceptionGO:000760130.013
regulation of blood circulationGO:19035221100.013
single organism reproductive processGO:00447022970.013
regulation of membrane potentialGO:00423911100.013
response to glucocorticoidGO:00513842230.013
regulation of cellular component movementGO:00512701500.013
regulation of activation of jak2 kinase activityGO:001053410.013
cellular response to growth factor stimulusGO:00713631620.013
regulation of membrane repolarizationGO:006030610.013
regulation of anatomical structure morphogenesisGO:00226031410.012
lipid catabolic processGO:0016042460.012
negative regulation of signalingGO:00230571570.012
regulation of smooth muscle cell migrationGO:0014910360.012
formation of primary germ layerGO:000170410.012
negative regulation of growthGO:0045926370.012
phospholipid metabolic processGO:0006644610.012
cellular amino acid metabolic processGO:00065201070.012
single organism membrane organizationGO:0044802740.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
muscle cell migrationGO:0014812360.012
cellular chemical homeostasisGO:00550822470.012
hematopoietic progenitor cell differentiationGO:000224420.012
organophosphate biosynthetic processGO:00904071430.012
multicellular organism growthGO:003526410.012
circulatory system developmentGO:00723591340.012
camp metabolic processGO:0046058630.012
cellular modified amino acid biosynthetic processGO:0042398180.012
cell cycleGO:00070491010.012
neuron developmentGO:00486662860.012
positive regulation of transportGO:00510502450.012
maintenance of locationGO:0051235170.012
gtp catabolic processGO:0006184710.012
positive regulation of purine nucleotide biosynthetic processGO:1900373360.011
telencephalon developmentGO:0021537620.011
response to estrogenGO:00436272320.011
respiratory gaseous exchangeGO:000758540.011
ribonucleoside triphosphate catabolic processGO:00092031220.011
negative regulation of cell developmentGO:0010721820.011
endocrine system developmentGO:0035270300.011
purine ribonucleoside catabolic processGO:00461301240.011
protein complex biogenesisGO:00702712630.011
nucleoside triphosphate catabolic processGO:00091431230.011
response to hexoseGO:00097461440.011
regulation of activation of janus kinase activityGO:001053310.011
mesoderm morphogenesisGO:004833210.011
guanosine containing compound catabolic processGO:1901069710.011
regulation of transcription regulatory region dna bindingGO:200067740.011
positive regulation of vasodilationGO:0045909290.011
olfactory learningGO:000835510.011
negative regulation of catalytic activityGO:00430861030.011
vasoconstrictionGO:0042310540.011
glycosyl compound catabolic processGO:19016581260.011
response to ketoneGO:19016541820.011
respiratory system processGO:000301630.011
neurotransmitter gated ion channel clusteringGO:007257830.011
regulation of calcium ion transportGO:0051924770.011
negative regulation of gene expressionGO:00106291990.010
positive regulation of nucleoside metabolic processGO:0045979550.010
regulation of cyclic nucleotide metabolic processGO:0030799510.010
response to temperature stimulusGO:0009266940.010
mesoderm formationGO:000170710.010
negative regulation of neuron projection developmentGO:0010977460.010
tube developmentGO:0035295890.010
regulation of transferase activityGO:00513381230.010
regulation of transmembrane transportGO:00347621220.010
cell migrationGO:00164771970.010
negative regulation of synaptic transmission dopaminergicGO:003222740.010
positive regulation of programmed cell deathGO:00430681570.010
response to dexamethasoneGO:0071548490.010
hepaticobiliary system developmentGO:0061008900.010

Espn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.034
Human
eye and adnexa diseaseDOID:149200.034
disease of anatomical entityDOID:700.034
Human
sensory system diseaseDOID:005015500.034
Human
eye diseaseDOID:561400.025
muscle tissue diseaseDOID:6600.012
muscular diseaseDOID:008000000.012
musculoskeletal system diseaseDOID:1700.012
myopathyDOID:42300.012
night blindnessDOID:849900.011
retinal diseaseDOID:567900.011
retinal degenerationDOID:846600.010
retinitis pigmentosaDOID:1058400.010