IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Plekhn1

pleckstrin homology domain containing, family N member 1

(Aliases: RGD1311019)

Entrez: 298694
Ensembl: ENSRNOG00000020295
RGD: 1311019
UniProtKB: D3Z815

Process Predictions
Disease Predictions

Plekhn1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
positive regulation of locomotion	GO:0040017	102	0.281
oxoacid metabolic process	GO:0043436	290	0.154
organonitrogen compound catabolic process	GO:1901565	179	0.103
organic cyclic compound catabolic process	GO:1901361	175	0.082
organic substance catabolic process	GO:1901575	316	0.074
carboxylic acid metabolic process	GO:0019752	289	0.065
response to inorganic substance	GO:0010035	377	0.060
single organism catabolic process	GO:0044712	283	0.055
organic acid metabolic process	GO:0006082	292	0.053
regulation of gtpase activity	GO:0043087	57	0.052
catabolic process	GO:0009056	351	0.051
cellular amino acid metabolic process	GO:0006520	107	0.043
immune system process	GO:0002376	204	0.041
regulation of molecular function	GO:0065009	398	0.041
carbohydrate derivative metabolic process	GO:1901135	346	0.040
response to extracellular stimulus	GO:0009991	380	0.039
gtp catabolic process	GO:0006184	71	0.034
purine nucleoside catabolic process	GO:0006152	124	0.032
cellular modified amino acid metabolic process	GO:0006575	61	0.030
localization of cell	GO:0051674	202	0.030
regulation of locomotion	GO:0040012	148	0.030
negative regulation of metabolic process	GO:0009892	331	0.029
cellular ketone metabolic process	GO:0042180	51	0.029
guanosine containing compound metabolic process	GO:1901068	74	0.029
signal release	GO:0023061	145	0.029
taxis	GO:0042330	67	0.028
small gtpase mediated signal transduction	GO:0007264	36	0.028
positive regulation of apoptotic process	GO:0043065	154	0.028
cellular catabolic process	GO:0044248	295	0.026
glycosyl compound metabolic process	GO:1901657	182	0.025
cellular nitrogen compound catabolic process	GO:0044270	163	0.025
positive regulation of cell death	GO:0010942	184	0.025
ras protein signal transduction	GO:0007265	29	0.025
heterocycle catabolic process	GO:0046700	167	0.025
guanosine containing compound catabolic process	GO:1901069	71	0.023
regulation of cell projection organization	GO:0031344	175	0.023
aromatic compound catabolic process	GO:0019439	168	0.021
nucleoside phosphate metabolic process	GO:0006753	283	0.021
positive regulation of transport	GO:0051050	245	0.020
regulation of apoptotic process	GO:0042981	335	0.020
glycosyl compound catabolic process	GO:1901658	126	0.020
nucleoside catabolic process	GO:0009164	126	0.020
regulation of exocytosis	GO:0017157	37	0.020
synaptic vesicle priming	GO:0016082	4	0.020
macromolecular complex assembly	GO:0065003	273	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.020
regulation of cellular ketone metabolic process	GO:0010565	27	0.019
gland development	GO:0048732	155	0.019
monosaccharide metabolic process	GO:0005996	61	0.019
cellular response to tumor necrosis factor	GO:0071356	46	0.019
positive regulation of neuron projection development	GO:0010976	99	0.018
aging	GO:0007568	241	0.018
response to nutrient levels	GO:0031667	370	0.018
regulation of hydrolase activity	GO:0051336	143	0.017
nucleoside metabolic process	GO:0009116	179	0.017
gtp metabolic process	GO:0046039	72	0.017
neuron differentiation	GO:0030182	368	0.017
sodium ion transmembrane transport	GO:0035725	67	0.017
transmission of nerve impulse	GO:0019226	42	0.017
response to oxidative stress	GO:0006979	186	0.017
inorganic ion transmembrane transport	GO:0098660	229	0.017
single organism biosynthetic process	GO:0044711	342	0.017
ion transmembrane transport	GO:0034220	365	0.017
regulation of ras gtpase activity	GO:0032318	32	0.017
multicellular organism growth	GO:0035264	1	0.016
regulation of catabolic process	GO:0009894	113	0.016
response to external biotic stimulus	GO:0043207	221	0.016
regulation of purine nucleotide catabolic process	GO:0033121	65	0.016
positive regulation of cell projection organization	GO:0031346	111	0.016
protein complex assembly	GO:0006461	263	0.016
negative regulation of extrinsic apoptotic signaling pathway	GO:2001237	4	0.015
regulation of small gtpase mediated signal transduction	GO:0051056	48	0.015
positive regulation of catalytic activity	GO:0043085	184	0.015
regulation of cellular amine metabolic process	GO:0033238	8	0.015
rna biosynthetic process	GO:0032774	380	0.015
ribonucleoside catabolic process	GO:0042454	126	0.015
positive regulation of molecular function	GO:0044093	230	0.014
regulation of cellular amino acid metabolic process	GO:0006521	2	0.014
amine metabolic process	GO:0009308	38	0.014
cellular amine metabolic process	GO:0044106	38	0.014
exocytosis	GO:0006887	60	0.014
response to metal ion	GO:0010038	253	0.014
apoptotic process	GO:0006915	381	0.014
regulation of cell migration	GO:0030334	128	0.014
cell projection organization	GO:0030030	302	0.013
cellular response to hormone stimulus	GO:0032870	247	0.013
vesicle mediated transport	GO:0016192	181	0.013
negative regulation of response to stimulus	GO:0048585	155	0.013
adult locomotory behavior	GO:0008344	4	0.013
synaptic vesicle exocytosis	GO:0016079	15	0.013
response to carbohydrate	GO:0009743	183	0.013
purine nucleotide catabolic process	GO:0006195	136	0.013
nucleobase containing small molecule metabolic process	GO:0055086	316	0.013
defense response to gram negative bacterium	GO:0050829	3	0.013
fucosylation	GO:0036065	2	0.013
nucleoside phosphate catabolic process	GO:1901292	140	0.013
axis specification	GO:0009798	4	0.013
regulation of rna biosynthetic process	GO:2001141	381	0.013
positive regulation of programmed cell death	GO:0043068	157	0.013
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.013
purine containing compound catabolic process	GO:0072523	138	0.013
hepaticobiliary system development	GO:0061008	90	0.013
positive regulation of response to stimulus	GO:0048584	285	0.013
regulation of ras protein signal transduction	GO:0046578	45	0.013
regulation of vesicle mediated transport	GO:0060627	81	0.013
female sex differentiation	GO:0046660	59	0.013
nucleotide catabolic process	GO:0009166	139	0.013
defense response to gram positive bacterium	GO:0050830	2	0.012
intracellular signal transduction	GO:0035556	314	0.012
tumor necrosis factor mediated signaling pathway	GO:0033209	4	0.012
regulation of phosphorus metabolic process	GO:0051174	349	0.012
regulation of membrane potential	GO:0042391	110	0.012
nucleoside triphosphate metabolic process	GO:0009141	144	0.012
regulation of catalytic activity	GO:0050790	304	0.012
organophosphate catabolic process	GO:0046434	148	0.012
regulation of cellular localization	GO:0060341	263	0.012
organelle organization	GO:0006996	266	0.012
transcription dna templated	GO:0006351	377	0.012
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.012
nucleic acid templated transcription	GO:0097659	379	0.012
nucleobase containing compound catabolic process	GO:0034655	152	0.012
hormone metabolic process	GO:0042445	69	0.011
single organism carbohydrate metabolic process	GO:0044723	118	0.011
lipid metabolic process	GO:0006629	283	0.011
rna metabolic process	GO:0016070	406	0.011
dna integrity checkpoint	GO:0031570	2	0.011
secretion by cell	GO:0032940	248	0.011
transmembrane transport	GO:0055085	412	0.011
negative regulation of gene expression	GO:0010629	199	0.011
secretion	GO:0046903	307	0.011
sex differentiation	GO:0007548	113	0.011
protein autophosphorylation	GO:0046777	66	0.011
regulation of nucleoside metabolic process	GO:0009118	66	0.011
positive regulation of neuron differentiation	GO:0045666	126	0.011
protein localization	GO:0008104	191	0.011
negative regulation of transcription dna templated	GO:0045892	116	0.011
transcription from rna polymerase ii promoter	GO:0006366	252	0.011
regulation of neuron differentiation	GO:0045664	208	0.011
antigen receptor mediated signaling pathway	GO:0050851	1	0.010
regulation of nucleotide catabolic process	GO:0030811	65	0.010
regulation of nucleotide metabolic process	GO:0006140	117	0.010
cell cycle checkpoint	GO:0000075	2	0.010
macromolecule catabolic process	GO:0009057	58	0.010
rho protein signal transduction	GO:0007266	11	0.010
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.010
response to reactive oxygen species	GO:0000302	120	0.010
organophosphate biosynthetic process	GO:0090407	143	0.010
response to nutrient	GO:0007584	248	0.010
positive regulation of cell communication	GO:0010647	271	0.010
locomotion	GO:0040011	237	0.010

Plekhn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.019
disease of anatomical entity	DOID:7	0.019
musculoskeletal system disease	DOID:17	0.012
central nervous system disease	DOID:331	0.011

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