Rattus norvegicus

8 known processes

Mx2

myxovirus (influenza virus) resistance 2

(Aliases: Mx3)

Mx2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to biotic stimulusGO:00096072260.598
response to other organismGO:00517072200.258
response to cytokineGO:00340972150.255
immune responseGO:00069551040.151
cellular response to peptide hormone stimulusGO:00713751200.141
cellular response to endogenous stimulusGO:00714953770.140
positive regulation of multicellular organismal processGO:00512403870.134
response to external biotic stimulusGO:00432072210.118
nucleotide metabolic processGO:00091172790.102
regulation of cell proliferationGO:00421273590.101
response to extracellular stimulusGO:00099913800.096
organophosphate metabolic processGO:00196373700.093
intracellular signal transductionGO:00355563140.089
homeostatic processGO:00425923310.087
cellular response to oxygen containing compoundGO:19017013860.086
transcription dna templatedGO:00063513770.085
nucleoside phosphate metabolic processGO:00067532830.080
regulation of apoptotic processGO:00429813350.076
transcription from rna polymerase ii promoterGO:00063662520.074
amine metabolic processGO:0009308380.067
regulation of phosphorus metabolic processGO:00511743490.065
regulation of cellular component organizationGO:00511283680.063
chemical homeostasisGO:00488782920.063
negative regulation of nitrogen compound metabolic processGO:00511721610.062
cation transportGO:00068123820.062
regulation of cell developmentGO:00602842630.062
reproductive processGO:00224143720.061
response to inorganic substanceGO:00100353770.061
rna metabolic processGO:00160704060.058
regulation of programmed cell deathGO:00430673410.058
negative regulation of macromolecule metabolic processGO:00106052600.057
organonitrogen compound biosynthetic processGO:19015661670.057
regulation of metanephros developmentGO:007221540.056
organic acid metabolic processGO:00060822920.056
response to mechanical stimulusGO:00096121340.055
neuron developmentGO:00486662860.054
cell projection organizationGO:00300303020.054
response to nutrientGO:00075842480.054
positive regulation of phosphorus metabolic processGO:00105622620.053
rna biosynthetic processGO:00327743800.052
cellular response to hormone stimulusGO:00328702470.052
defense responseGO:00069521940.052
cellular response to organonitrogen compoundGO:00714171970.051
neuron differentiationGO:00301823680.051
jak stat cascadeGO:0007259260.051
regulation of molecular functionGO:00650093980.051
cellular chemical homeostasisGO:00550822470.050
macromolecular complex assemblyGO:00650032730.050
negative regulation of metabolic processGO:00098923310.049
negative regulation of cellular metabolic processGO:00313242810.049
oxoacid metabolic processGO:00434362900.048
response to nutrient levelsGO:00316673700.048
carbohydrate derivative metabolic processGO:19011353460.048
response to estrogenGO:00436272320.047
regulation of signal transductionGO:00099663180.046
secretionGO:00469033070.046
regulation of catalytic activityGO:00507903040.046
negative regulation of cellular biosynthetic processGO:00313271610.046
ribonucleotide metabolic processGO:00092592310.046
tyrosine phosphorylation of stat1 proteinGO:004250830.045
cellular response to stressGO:00335542690.045
purine containing compound biosynthetic processGO:0072522850.045
macromolecular complex subunit organizationGO:00439333390.045
single organism biosynthetic processGO:00447113420.044
metal ion transportGO:00300012890.044
regulation of rna metabolic processGO:00512523910.044
response to peptideGO:19016522920.044
organelle organizationGO:00069962660.043
central nervous system developmentGO:00074173110.043
response to lipopolysaccharideGO:00324961910.043
regulation of nucleic acid templated transcriptionGO:19035063800.042
regulation of neurogenesisGO:00507672470.042
regulation of rna biosynthetic processGO:20011413810.042
brain developmentGO:00074202470.042
positive regulation of cell deathGO:00109421840.042
nucleoside phosphate biosynthetic processGO:19012931020.042
cation homeostasisGO:00550801950.041
regulation of phosphate metabolic processGO:00192203490.041
response to peptide hormoneGO:00434342780.041
cellular response to organic cyclic compoundGO:00714072020.041
positive regulation of cellular biosynthetic processGO:00313282950.041
response to molecule of bacterial originGO:00022371940.041
apoptotic processGO:00069153810.041
cellular component assemblyGO:00226073600.040
positive regulation of response to stimulusGO:00485842850.040
cellular response to growth factor stimulusGO:00713631620.039
cellular response to cytokine stimulusGO:00713451270.039
neuron projection developmentGO:00311752730.039
carboxylic acid metabolic processGO:00197522890.039
positive regulation of nucleobase containing compound metabolic processGO:00459353190.039
regulation of cellular amine metabolic processGO:003323880.039
cellular response to peptideGO:19016531330.038
anatomical structure morphogenesisGO:00096532980.038
cellular amino acid metabolic processGO:00065201070.037
regulation of immune system processGO:00026821230.037
cellular component movementGO:00069282480.037
nucleic acid templated transcriptionGO:00976593790.037
cellular response to external stimulusGO:00714961180.036
regulation of neuron projection developmentGO:00109751610.036
positive regulation of nitrogen compound metabolic processGO:00511733340.036
response to growth factorGO:00708481890.036
regulation of intracellular signal transductionGO:19025312180.036
negative regulation of developmental processGO:00510931250.035
cellular ketone metabolic processGO:0042180510.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
regulation of cell differentiationGO:00455953200.035
regulation of phosphorylationGO:00423252480.034
ion homeostasisGO:00508012120.034
positive regulation of developmental processGO:00510942830.034
negative regulation of signalingGO:00230571570.034
protein complex subunit organizationGO:00718223020.033
regulation of purine nucleotide metabolic processGO:19005421150.033
rhythmic processGO:00485111560.033
regulation of immune responseGO:0050776550.032
protein complex biogenesisGO:00702712630.032
macromolecule localizationGO:00330362520.032
cellular amine metabolic processGO:0044106380.032
agingGO:00075682410.032
negative regulation of cell deathGO:00605482290.031
regulation of multicellular organismal developmentGO:20000263760.031
membrane organizationGO:0061024940.030
purine containing compound metabolic processGO:00725212530.030
regulation of response to stressGO:00801341260.030
positive regulation of phosphate metabolic processGO:00459372620.030
secretion by cellGO:00329402480.030
regulation of cellular amino acid metabolic processGO:000652120.030
blood circulationGO:00080151830.030
cellular ion homeostasisGO:00068731840.030
regulation of cellular localizationGO:00603412630.030
cellular divalent inorganic cation homeostasisGO:00725031620.029
nucleobase containing small molecule metabolic processGO:00550863160.029
response to bacteriumGO:00096172000.029
protein complex assemblyGO:00064612630.029
negative regulation of cell developmentGO:0010721820.029
positive regulation of transcription dna templatedGO:00458931970.029
positive regulation of cellular component organizationGO:00511302000.029
intracellular transportGO:00469071850.029
response to retinoic acidGO:0032526630.029
purine nucleotide metabolic processGO:00061632290.029
response to radiationGO:00093141370.029
single organism intracellular transportGO:19025821660.029
response to estradiolGO:00323551640.029
negative regulation of cell communicationGO:00106481580.029
regulation of nervous system developmentGO:00519602640.029
negative regulation of nervous system developmentGO:0051961790.028
response to metal ionGO:00100382530.028
positive regulation of cell projection organizationGO:00313461110.028
regulation of mesenchymal cell proliferationGO:001046440.028
cellular component morphogenesisGO:00329891550.028
positive regulation of macromolecule biosynthetic processGO:00105572470.028
single organism reproductive processGO:00447022970.028
response to ethanolGO:00454711620.028
carbohydrate metabolic processGO:00059751300.028
positive regulation of tolerance induction dependent upon immune responseGO:000265410.028
positive regulation of biosynthetic processGO:00098913190.028
positive regulation of rna biosynthetic processGO:19026801970.027
regulation of transcription dna templatedGO:00063553740.027
ribose phosphate metabolic processGO:00196932350.027
positive regulation of gene expressionGO:00106282440.027
regulation of protein metabolic processGO:00512462890.027
regulation of cellular protein metabolic processGO:00322682670.027
cellular component biogenesisGO:00440853680.026
cellular homeostasisGO:00197252520.026
negative regulation of phosphate metabolic processGO:0045936800.026
positive regulation of transportGO:00510502450.026
protein oligomerizationGO:00512591910.026
protein localizationGO:00081041910.026
regulation of nucleotide metabolic processGO:00061401170.026
positive regulation of programmed cell deathGO:00430681570.026
regulation of tolerance induction to nonself antigenGO:000265510.026
positive regulation of rna metabolic processGO:00512542030.026
positive regulation of cell proliferationGO:00082842490.026
inflammatory responseGO:00069541500.025
negative regulation of macromolecule biosynthetic processGO:00105581480.025
negative regulation of cell differentiationGO:0045596990.025
response to oxidative stressGO:00069791860.025
response to hexoseGO:00097461440.024
developmental process involved in reproductionGO:00030061590.024
response to oxygen levelsGO:00704822650.024
positive regulation of signalingGO:00230562700.024
regulation of secretion by cellGO:19035302080.024
multicellular organismal reproductive processGO:00486092330.024
response to monosaccharideGO:00342841590.024
regulation of neuron differentiationGO:00456642080.024
catabolic processGO:00090563510.024
transmembrane transportGO:00550854120.024
cell cell signalingGO:00072673350.023
multi organism reproductive processGO:00447032620.023
programmed cell deathGO:00125013920.023
purine ribonucleotide metabolic processGO:00091502270.023
positive regulation of neuron projection developmentGO:0010976990.023
reproductionGO:00000032450.023
positive regulation of intracellular signal transductionGO:19025331380.023
negative regulation of multicellular organismal processGO:00512412030.023
synaptic transmissionGO:00072682350.023
inorganic cation transmembrane transportGO:00986622020.023
regulation of neuron deathGO:19012141150.023
response to carbohydrateGO:00097431830.023
response to vitaminGO:00332731310.023
negative regulation of innate immune responseGO:004582440.022
positive regulation of cell developmentGO:00107201760.022
establishment of protein localizationGO:00451841410.022
head developmentGO:00603222470.022
negative regulation of viral genome replicationGO:004507110.022
Human
response to tumor necrosis factorGO:0034612560.022
protein phosphorylationGO:00064683450.022
regulation of ion transportGO:00432692450.022
response to glucocorticoidGO:00513842230.022
liver developmentGO:0001889900.022
smooth muscle cell proliferationGO:0048659770.021
purine nucleotide biosynthetic processGO:0006164830.021
cellular response to nitrogen compoundGO:19016992100.021
mesenchymal cell proliferationGO:001046340.021
monovalent inorganic cation transportGO:00156721720.021
nucleotide biosynthetic processGO:0009165980.021
negative regulation of kidney developmentGO:009018520.021
cell differentiation involved in kidney developmentGO:006100540.021
cellular protein localizationGO:00346131220.021
regulation of cellular ketone metabolic processGO:0010565270.021
response to woundingGO:00096112540.021
response to acid chemicalGO:00011012220.021
regulation of cell projection organizationGO:00313441750.021
cation transmembrane transportGO:00986552630.021
regulation of protein modification processGO:00313991940.020
cellular cation homeostasisGO:00300031800.020
sodium ion transportGO:0006814820.020
positive regulation of apoptotic processGO:00430651540.020
negative regulation of cellular component organizationGO:0051129830.020
metal ion homeostasisGO:00550651860.020
response to insulinGO:00328681330.020
negative regulation of rna metabolic processGO:00512531230.020
negative regulation of phosphorus metabolic processGO:0010563800.020
multicellular organism reproductionGO:00325042330.020
carbohydrate derivative biosynthetic processGO:19011371240.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
response to organophosphorusGO:00466831020.020
negative regulation of protein phosphorylationGO:0001933440.020
positive regulation of nucleic acid templated transcriptionGO:19035081970.020
negative regulation of cell projection organizationGO:0031345500.020
cellular response to lipidGO:00713962010.020
response to hydrogen peroxideGO:0042542890.019
positive regulation of cell differentiationGO:00455972170.019
regulation of cell morphogenesis involved in differentiationGO:0010769720.019
cytokine productionGO:0001816610.019
gonad developmentGO:00084061040.019
neuron deathGO:00709971270.019
immune system processGO:00023762040.019
single organism membrane organizationGO:0044802740.019
calcium ion transportGO:00068161310.018
circulatory system processGO:00030131830.018
organophosphate biosynthetic processGO:00904071430.018
regulation of hormone levelsGO:00108171870.018
regulation of kinase activityGO:00435491170.018
reproductive system developmentGO:00614581280.018
positive regulation of nervous system developmentGO:00519621780.018
response to dsrnaGO:004333190.018
Zebrafish
positive regulation of catalytic activityGO:00430851840.018
sex differentiationGO:00075481130.018
antigen processing and presentation of endogenous antigenGO:001988310.017
response to purine containing compoundGO:00140741260.017
positive regulation of immune system processGO:0002684900.017
negative regulation of biosynthetic processGO:00098901680.017
neurological system processGO:00508772190.017
protein transportGO:00150311320.017
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.017
peptidyl amino acid modificationGO:00181931260.017
cellular response to insulin stimulusGO:0032869810.017
protection from natural killer cell mediated cytotoxicityGO:004227020.017
negative regulation of gene expressionGO:00106291990.017
regenerationGO:00310991630.017
mesoderm developmentGO:000749820.017
negative regulation of metanephros developmentGO:007221720.016
positive regulation of cellular amine metabolic processGO:003324030.016
g protein coupled receptor signaling pathwayGO:00071862420.016
positive regulation of neurogenesisGO:00507691650.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
negative regulation of signal transductionGO:0009968830.016
regulation of membrane potentialGO:00423911100.016
anion transportGO:00068201780.016
regulation of smooth muscle cell proliferationGO:0048660750.016
wound healingGO:00420601220.016
response to virusGO:0009615170.016
positive regulation of cytosolic calcium ion concentrationGO:00072041220.016
tissue developmentGO:00098882520.016
regulation of synaptic transmissionGO:00508041410.015
single organism cellular localizationGO:19025801020.015
cell type specific apoptotic processGO:00972851340.015
neuron apoptotic processGO:0051402880.015
negative regulation of natural killer cell mediated immunityGO:000271640.015
positive regulation of signal transductionGO:00099671750.015
female sex differentiationGO:0046660590.015
regulation of nucleotide biosynthetic processGO:0030808470.015
glucose homeostasisGO:0042593750.015
mesenchymal cell differentiation involved in renal system developmentGO:200101210.015
regulation of purine nucleotide biosynthetic processGO:1900371460.015
regulation of defense responseGO:0031347680.015
cellular calcium ion homeostasisGO:00068741600.015
acute inflammatory responseGO:0002526580.015
nitrogen compound transportGO:00717052290.015
response to corticosteroidGO:00319602350.015
divalent inorganic cation transportGO:00725111340.015
response to hypoxiaGO:00016662310.015
positive regulation of purine nucleotide metabolic processGO:1900544910.015
single organism catabolic processGO:00447122830.015
single organism organelle organizationGO:19025891800.015
behaviorGO:00076102050.015
renal system developmentGO:0072001670.015
proteolysisGO:00065081750.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
innate immune responseGO:0045087350.015
cellular response to nutrient levelsGO:0031669600.014
response to decreased oxygen levelsGO:00362932370.014
nucleoside metabolic processGO:00091161790.014
purine nucleoside metabolic processGO:00422781690.014
cellular response to abiotic stimulusGO:0071214850.014
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.014
positive regulation of mesenchymal cell proliferationGO:000205340.014
negative regulation of neuron deathGO:1901215690.014
gland developmentGO:00487321550.014
organ morphogenesisGO:0009887750.014
regulation of protein phosphorylationGO:00019321830.014
negative regulation of protein metabolic processGO:00512481140.014
peptide transportGO:0015833970.014
ribonucleotide biosynthetic processGO:0009260850.014
response to glucoseGO:00097491360.014
development of primary female sexual characteristicsGO:0046545560.014
development of primary sexual characteristicsGO:00451371070.014
ribonucleoside metabolic processGO:00091191740.014
growthGO:00400071650.014
negative regulation of neurogenesisGO:0050768780.014
response to reactive oxygen speciesGO:00003021200.014
regulation of cell morphogenesisGO:0022604770.014
purine ribonucleotide biosynthetic processGO:0009152810.014
calcium ion homeostasisGO:00550741620.014
signal transduction by phosphorylationGO:00230141440.014
regulation of response to external stimulusGO:00321011060.014
multi multicellular organism processGO:00447061380.014
cellular catabolic processGO:00442482950.014
regulation of system processGO:00440572080.014
ribose phosphate biosynthetic processGO:0046390870.013
regulation of tolerance induction dependent upon immune responseGO:000265210.013
ion transmembrane transportGO:00342203650.013
urogenital system developmentGO:0001655780.013
purine ribonucleoside metabolic processGO:00461281680.013
kidney developmentGO:0001822670.013
negative regulation of neuron differentiationGO:0045665620.013
response to campGO:0051591910.013
glycosyl compound catabolic processGO:19016581260.013
cytosolic calcium ion homeostasisGO:00514801400.013
eye morphogenesisGO:004859240.013
peptide secretionGO:0002790860.013
response to ionizing radiationGO:0010212590.013
negative regulation of phosphorylationGO:0042326570.013
positive regulation of smooth muscle cell proliferationGO:0048661510.013
positive regulation of neuron differentiationGO:00456661260.013
gamete generationGO:00072761240.013
response to temperature stimulusGO:0009266940.013
cell morphogenesis involved in differentiationGO:00009041190.013
negative regulation of programmed cell deathGO:00430691830.013
metanephric tubule developmentGO:007217040.013
axis specificationGO:000979840.013
response to starvationGO:0042594590.013
negative regulation of rna biosynthetic processGO:19026791180.012
multicellular organism growthGO:003526410.012
cell morphogenesisGO:00009021420.012
regulation of transferase activityGO:00513381230.012
response to toxic substanceGO:00096361330.012
organophosphate catabolic processGO:00464341480.012
purine nucleoside monophosphate metabolic processGO:0009126840.012
positive regulation of ion transportGO:0043270940.012
cellular metal ion homeostasisGO:00068751720.012
cellular macromolecule localizationGO:00707271220.012
immune effector processGO:0002252530.012
cyclic nucleotide metabolic processGO:0009187800.012
positive regulation of molecular functionGO:00440932300.012
cellular response to extracellular stimulusGO:0031668730.012
glycosyl compound metabolic processGO:19016571820.012
localization of cellGO:00516742020.012
cellular response to interleukin 1GO:0071347370.012
positive regulation of secretion by cellGO:19035321280.012
metanephric renal vesicle morphogenesisGO:007228330.012
circadian rhythmGO:0007623880.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
positive regulation of cell communicationGO:00106472710.012
positive regulation of cyclic nucleotide metabolic processGO:0030801370.012
ribonucleoside monophosphate metabolic processGO:0009161880.012
cell cycle checkpointGO:000007520.012
regulation of reactive oxygen species biosynthetic processGO:190342650.012
reproductive structure developmentGO:00486081280.012
single organism carbohydrate metabolic processGO:00447231180.012
alcohol metabolic processGO:0006066770.012
negative regulation of molecular functionGO:00440921330.012
inorganic ion transmembrane transportGO:00986602290.012
muscle tissue developmentGO:0060537580.011
sexual reproductionGO:00199531480.011
small molecule biosynthetic processGO:00442831240.011
negative regulation of catalytic activityGO:00430861030.011
muscle cell proliferationGO:0033002840.011
ovulation cycle processGO:0022602500.011
ossificationGO:0001503700.011
negative regulation of jak stat cascadeGO:004642630.011
cardiac chamber developmentGO:000320510.011
regulation of viral genome replicationGO:004506920.011
Human
response to alkaloidGO:00432791320.011
tissue remodelingGO:0048771400.011
reactive oxygen species biosynthetic processGO:190340980.011
developmental growthGO:00485891000.011
cell motilityGO:00488702020.011
oxidation reduction processGO:00551143040.011
metanephric mesenchymal cell differentiationGO:007216210.011
regulation of camp metabolic processGO:0030814430.011
organic substance catabolic processGO:19015753160.011
nucleoside triphosphate metabolic processGO:00091411440.011
chromosome segregationGO:000705920.011
antigen processing and presentation of endogenous peptide antigen via mhc class iGO:001988510.011
second messenger mediated signalingGO:0019932510.011
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000334020.011
amide transportGO:00428861050.011
negative regulation of immune system processGO:0002683390.011
negative regulation of response to stimulusGO:00485851550.011
small gtpase mediated signal transductionGO:0007264360.011
hepaticobiliary system developmentGO:0061008900.011
axon developmentGO:0061564960.011
positive regulation of interleukin 1 beta secretionGO:005071830.011
ovulation cycleGO:0042698670.011
positive regulation of nucleotide metabolic processGO:0045981910.010
activation of cysteine type endopeptidase activityGO:009720240.010
purine nucleoside triphosphate metabolic processGO:00091441410.010
carbohydrate homeostasisGO:0033500750.010
negative regulation of transcription dna templatedGO:00458921160.010
negative regulation of cellular amine metabolic processGO:003323930.010
sensory perceptionGO:00076001010.010
action potentialGO:0001508540.010
cardiovascular system developmentGO:00723581340.010
divalent inorganic cation homeostasisGO:00725071650.010
regulation of nephron tubule epithelial cell differentiationGO:007218210.010
cellular response to tumor necrosis factorGO:0071356460.010
regulation of cellular component movementGO:00512701500.010
cytoplasmic transportGO:00164821150.010
insulin secretionGO:0030073690.010

Mx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.020
disease of anatomical entityDOID:700.015
urinary system diseaseDOID:1800.015
severe combined immunodeficiencyDOID:62700.014
combined t cell and b cell immunodeficiencyDOID:62800.014
immune system diseaseDOID:291400.014
primary immunodeficiency diseaseDOID:61200.014
nervous system diseaseDOID:86300.014