Rattus norvegicus

73 known processes

Alox5ap

arachidonate 5-lipoxygenase activating protein

Alox5ap biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
programmed cell deathGO:00125013920.582
immune system processGO:00023762040.404
apoptotic processGO:00069153810.369
response to external biotic stimulusGO:00432072210.355
Rat
response to biotic stimulusGO:00096072260.343
Rat
response to lipopolysaccharideGO:00324961910.292
Rat
positive regulation of immune system processGO:0002684900.276
response to other organismGO:00517072200.229
Rat
defense responseGO:00069521940.224
regulation of apoptotic processGO:00429813350.189
single organism biosynthetic processGO:00447113420.171
regulation of immunoglobulin productionGO:000263740.165
inflammatory responseGO:00069541500.162
cellular response to endogenous stimulusGO:00714953770.160
response to molecule of bacterial originGO:00022371940.152
Rat
response to glucocorticoidGO:00513842230.151
positive regulation of response to stimulusGO:00485842850.142
negative regulation of cell proliferationGO:00082851190.140
response to corticosteroidGO:00319602350.137
intracellular signal transductionGO:00355563140.127
regulation of phosphate metabolic processGO:00192203490.112
positive regulation of programmed cell deathGO:00430681570.110
regulation of cell proliferationGO:00421273590.105
positive regulation of cell deathGO:00109421840.105
response to monosaccharideGO:00342841590.103
protein complex subunit organizationGO:00718223020.103
positive regulation of apoptotic processGO:00430651540.100
neurological system processGO:00508772190.095
regulation of immune system processGO:00026821230.094
regulation of programmed cell deathGO:00430673410.094
regulation of cellular component organizationGO:00511283680.092
reproductionGO:00000032450.090
regulation of cell activationGO:0050865500.089
response to oxygen levelsGO:00704822650.089
organophosphate metabolic processGO:00196373700.084
mapk cascadeGO:00001651400.083
oxoacid metabolic processGO:00434362900.081
carboxylic acid metabolic processGO:00197522890.080
positive regulation of multicellular organismal processGO:00512403870.078
cellular amine metabolic processGO:0044106380.075
response to bacteriumGO:00096172000.074
Rat
behaviorGO:00076102050.073
metal ion transportGO:00300012890.071
regulation of cellular protein metabolic processGO:00322682670.069
myeloid cell apoptotic processGO:003302860.068
positive regulation of phosphorylationGO:00423271770.067
divalent metal ion transportGO:00708381320.067
response to decreased oxygen levelsGO:00362932370.067
chemical homeostasisGO:00488782920.067
regulation of cell differentiationGO:00455953200.066
regulation of catalytic activityGO:00507903040.065
agingGO:00075682410.065
inorganic ion transmembrane transportGO:00986602290.064
negative regulation of nervous system developmentGO:0051961790.063
regulation of cellular amino acid metabolic processGO:000652120.062
amine metabolic processGO:0009308380.062
b cell mediated immunityGO:001972440.061
response to carbohydrateGO:00097431830.061
positive regulation of developmental processGO:00510942830.061
regulation of cellular ketone metabolic processGO:0010565270.061
myeloid leukocyte activationGO:0002274360.059
vesicle mediated transportGO:00161921810.058
response to hexoseGO:00097461440.058
biological adhesionGO:00226101100.057
positive regulation of transportGO:00510502450.057
positive regulation of immune responseGO:0050778420.056
single organism cell adhesionGO:0098602460.056
response to woundingGO:00096112540.056
regulation of multicellular organismal developmentGO:20000263760.055
immunoglobulin mediated immune responseGO:001606440.055
carbohydrate derivative metabolic processGO:19011353460.054
positive regulation of signalingGO:00230562700.054
small molecule biosynthetic processGO:00442831240.053
regulation of cytokine productionGO:0001817560.053
positive regulation of cellular biosynthetic processGO:00313282950.051
organic acid metabolic processGO:00060822920.051
reactive oxygen species metabolic processGO:0072593370.051
homeostatic processGO:00425923310.050
response to transition metal nanoparticleGO:19902671220.050
cellular response to oxygen containing compoundGO:19017013860.050
Rat
central nervous system developmentGO:00074173110.049
negative regulation of cellular metabolic processGO:00313242810.049
response to cytokineGO:00340972150.049
innate immune responseGO:0045087350.048
negative regulation of molecular functionGO:00440921330.048
negative regulation of developmental processGO:00510931250.048
response to radiationGO:00093141370.048
negative regulation of cell differentiationGO:0045596990.046
immune response regulating signaling pathwayGO:0002764190.045
negative regulation of multicellular organismal processGO:00512412030.043
inorganic cation transmembrane transportGO:00986622020.043
positive regulation of cell communicationGO:00106472710.041
multicellular organism reproductionGO:00325042330.041
catabolic processGO:00090563510.040
response to metal ionGO:00100382530.040
Human
regulation of immune responseGO:0050776550.040
neuron projection developmentGO:00311752730.040
regulation of nervous system developmentGO:00519602640.039
cellular response to interferon gammaGO:0071346140.039
immune effector processGO:0002252530.039
cation transportGO:00068123820.039
organonitrogen compound catabolic processGO:19015651790.038
single organism organelle organizationGO:19025891800.038
neutrophil apoptotic processGO:000178140.038
cellular response to organic cyclic compoundGO:00714072020.038
response to glucoseGO:00097491360.037
cellular response to molecule of bacterial originGO:0071219560.037
Rat
regulation of cell developmentGO:00602842630.037
chemotaxisGO:0006935660.037
positive regulation of macromolecule biosynthetic processGO:00105572470.037
cell projection organizationGO:00300303020.037
phospholipid metabolic processGO:0006644610.037
divalent inorganic cation transportGO:00725111340.037
head developmentGO:00603222470.036
regulation of molecular functionGO:00650093980.036
negative regulation of apoptotic processGO:00430661810.036
negative regulation of programmed cell deathGO:00430691830.036
regulation of cellular amine metabolic processGO:003323880.036
multicellular organismal reproductive processGO:00486092330.036
regulation of neutrophil apoptotic processGO:003302940.036
positive regulation of intracellular signal transductionGO:19025331380.036
regulation of neurogenesisGO:00507672470.035
activation of immune responseGO:0002253260.035
response to peptideGO:19016522920.035
positive regulation of molecular functionGO:00440932300.035
transmembrane transportGO:00550854120.035
cellular amino acid metabolic processGO:00065201070.034
positive regulation of cell proliferationGO:00082842490.034
single organism catabolic processGO:00447122830.034
locomotionGO:00400112370.034
positive regulation of cell migrationGO:0030335960.034
cellular homeostasisGO:00197252520.034
response to zinc ionGO:0010043390.033
proteolysisGO:00065081750.033
regulation of kinase activityGO:00435491170.033
nucleoside phosphate metabolic processGO:00067532830.033
response to growth factorGO:00708481890.033
positive regulation of phosphorus metabolic processGO:00105622620.032
cellular response to lipidGO:00713962010.032
Rat
cellular component assemblyGO:00226073600.032
positive regulation of cell developmentGO:00107201760.032
hematopoietic progenitor cell differentiationGO:000224420.032
reproductive processGO:00224143720.032
regulation of reactive oxygen species metabolic processGO:2000377260.032
response to nutrient levelsGO:00316673700.032
Rat
leukotriene biosynthetic processGO:001937030.031
cellular response to interleukin 1GO:0071347370.031
regulation of hydrolase activityGO:00513361430.031
calcium ion transportGO:00068161310.030
regulation of anatomical structure sizeGO:00900661350.030
negative regulation of metabolic processGO:00098923310.030
cellular response to stressGO:00335542690.030
blood vessel morphogenesisGO:0048514580.030
neuron differentiationGO:00301823680.030
cellular metal ion homeostasisGO:00068751720.030
response to extracellular stimulusGO:00099913800.029
Rat
receptor mediated endocytosisGO:0006898420.029
nucleotide metabolic processGO:00091172790.029
regulation of phosphorus metabolic processGO:00511743490.029
regulation of metal ion transportGO:00109591180.029
protein phosphorylationGO:00064683450.029
positive regulation of cell differentiationGO:00455972170.028
carbohydrate derivative catabolic processGO:19011361470.028
response to organophosphorusGO:00466831020.028
regulation of system processGO:00440572080.028
multi organism reproductive processGO:00447032620.028
nucleoside triphosphate catabolic processGO:00091431230.027
cellular response to biotic stimulusGO:0071216590.027
Rat
positive regulation of catalytic activityGO:00430851840.027
positive regulation of cellular amino acid metabolic processGO:004576410.027
growthGO:00400071650.026
nitrogen compound transportGO:00717052290.026
rhythmic processGO:00485111560.026
response to purine containing compoundGO:00140741260.026
response to temperature stimulusGO:0009266940.026
cellular response to lipopolysaccharideGO:0071222550.026
Rat
response to nutrientGO:00075842480.026
Rat
transcription dna templatedGO:00063513770.026
regulation of immunoglobulin mediated immune responseGO:000288920.026
brain developmentGO:00074202470.025
response to hypoxiaGO:00016662310.025
t cell proliferationGO:0042098190.025
purine containing compound metabolic processGO:00725212530.025
regulation of intracellular signal transductionGO:19025312180.025
cellular response to growth factor stimulusGO:00713631620.025
positive regulation of neurogenesisGO:00507691650.025
negative regulation of gene expressionGO:00106291990.025
positive regulation of reactive oxygen species metabolic processGO:2000379160.025
monocarboxylic acid metabolic processGO:00327871520.025
cell adhesionGO:00071551100.024
positive regulation of response to external stimulusGO:0032103510.024
negative regulation of signal transductionGO:0009968830.024
cellular ketone metabolic processGO:0042180510.024
cellular cation homeostasisGO:00300031800.024
regulation of leukocyte activationGO:0002694450.024
positive regulation of phosphate metabolic processGO:00459372620.024
regulation of phosphorylationGO:00423252480.024
cellular chemical homeostasisGO:00550822470.024
peptidyl amino acid modificationGO:00181931260.023
regulation of smooth muscle cell proliferationGO:0048660750.023
positive regulation of lymphocyte migrationGO:200040310.023
positive regulation of cellular amine metabolic processGO:003324030.023
regulation of protein maturationGO:1903317500.023
regulation of lymphocyte activationGO:0051249340.023
reactive oxygen species biosynthetic processGO:190340980.023
negative regulation of immune system processGO:0002683390.023
positive regulation of cytoskeleton organizationGO:0051495260.023
positive regulation of secretionGO:00510471400.023
cytokine productionGO:0001816610.023
secretionGO:00469033070.023
protein complex assemblyGO:00064612630.023
regulation of defense responseGO:0031347680.023
negative regulation of neuron differentiationGO:0045665620.023
cell type specific apoptotic processGO:00972851340.022
lipid metabolic processGO:00066292830.022
anatomical structure morphogenesisGO:00096532980.022
response to ethanolGO:00454711620.022
lymphocyte activationGO:0046649430.022
regulation of homeostatic processGO:00328441010.022
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.022
positive regulation of biosynthetic processGO:00098913190.022
negative regulation of nitrogen compound metabolic processGO:00511721610.022
response to axon injuryGO:0048678590.022
Rat
cell motilityGO:00488702020.022
positive regulation of leukocyte activationGO:0002696300.022
purine ribonucleoside metabolic processGO:00461281680.022
protein complex biogenesisGO:00702712630.022
peptidyl tyrosine autophosphorylationGO:003808310.022
positive regulation of signal transductionGO:00099671750.021
icosanoid metabolic processGO:0006690380.021
small gtpase mediated signal transductionGO:0007264360.021
defense response to gram positive bacteriumGO:005083020.021
negative regulation of macromolecule metabolic processGO:00106052600.021
negative regulation of phosphorus metabolic processGO:0010563800.021
regulation of secretionGO:00510462240.021
negative regulation of protein metabolic processGO:00512481140.021
regenerationGO:00310991630.021
negative regulation of cellular protein metabolic processGO:00322691060.021
antigen processing and presentationGO:001988220.021
cytoskeleton organizationGO:00070101110.021
localization of cellGO:00516742020.020
response to interferon gammaGO:0034341200.020
cation homeostasisGO:00550801950.020
negative regulation of cell deathGO:00605482290.020
cellular response to cytokine stimulusGO:00713451270.020
cell activationGO:0001775970.020
regulation of muscle system processGO:0090257790.020
ras protein signal transductionGO:0007265290.020
cellular component movementGO:00069282480.020
response to ketoneGO:19016541820.020
negative regulation of neurogenesisGO:0050768780.020
regulation of cell growthGO:0001558850.020
macromolecular complex subunit organizationGO:00439333390.020
response to campGO:0051591910.020
organonitrogen compound biosynthetic processGO:19015661670.020
cell migrationGO:00164771970.020
response to inorganic substanceGO:00100353770.019
Human Rat
nucleobase containing small molecule metabolic processGO:00550863160.019
regulation of protein phosphorylationGO:00019321830.019
nucleoside catabolic processGO:00091641260.019
regulation of response to stressGO:00801341260.019
ion transmembrane transportGO:00342203650.019
regulation of reactive oxygen species biosynthetic processGO:190342650.019
g protein coupled receptor signaling pathwayGO:00071862420.019
regulation of leukocyte proliferationGO:0070663260.019
positive regulation of cytokine productionGO:0001819420.019
organophosphate biosynthetic processGO:00904071430.019
blood circulationGO:00080151830.019
positive regulation of nitrogen compound metabolic processGO:00511733340.019
vasculature developmentGO:0001944700.019
tissue developmentGO:00098882520.019
b cell differentiationGO:003018320.019
regulation of ion transmembrane transportGO:00347651210.019
cellular component morphogenesisGO:00329891550.019
calcium ion transmembrane transportGO:0070588700.019
purine nucleotide metabolic processGO:00061632290.018
response to vitaminGO:00332731310.018
Rat
cell cell signalingGO:00072673350.018
circadian rhythmGO:0007623880.018
positive regulation of lipid kinase activityGO:009021820.018
positive regulation of mapk cascadeGO:0043410920.018
regulation of response to external stimulusGO:00321011060.018
regulation of rna metabolic processGO:00512523910.018
negative regulation of catalytic activityGO:00430861030.018
gamete generationGO:00072761240.018
regulation of mononuclear cell proliferationGO:0032944260.018
cellular lipid metabolic processGO:00442552080.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
glycosyl compound metabolic processGO:19016571820.018
nucleoside metabolic processGO:00091161790.018
regulation of protein metabolic processGO:00512462890.018
regulation of membrane potentialGO:00423911100.018
rna biosynthetic processGO:00327743800.018
macromolecular complex assemblyGO:00650032730.017
positive regulation of cellular protein metabolic processGO:00322701670.017
circulatory system developmentGO:00723591340.017
aromatic compound catabolic processGO:00194391680.017
endocytosisGO:0006897840.017
cardiovascular system developmentGO:00723581340.017
renal system developmentGO:0072001670.017
humoral immune responseGO:0006959120.017
response to acid chemicalGO:00011012220.017
smooth muscle cell proliferationGO:0048659770.017
lipid biosynthetic processGO:00086101280.017
inflammatory cell apoptotic processGO:000692550.017
leukocyte mediated immunityGO:0002443280.017
regulation of cation channel activityGO:2001257230.017
regulation of organelle organizationGO:0033043800.017
negative regulation of cell developmentGO:0010721820.016
protein maturationGO:0051604680.016
regulation of growthGO:00400081050.016
regulation of nucleic acid templated transcriptionGO:19035063800.016
positive regulation of hydrolase activityGO:0051345860.016
regulation of dna metabolic processGO:0051052600.016
regulation of secretion by cellGO:19035302080.016
cellular response to steroid hormone stimulusGO:0071383930.016
regulation of lymphocyte proliferationGO:0050670260.016
ribose phosphate metabolic processGO:00196932350.016
multi multicellular organism processGO:00447061380.016
cellular response to glucocorticoid stimulusGO:0071385680.016
cellular calcium ion homeostasisGO:00068741600.016
developmental growthGO:00485891000.016
positive regulation of blood circulationGO:1903524650.016
transforming growth factor beta receptor signaling pathwayGO:0007179180.016
cellular catabolic processGO:00442482950.016
synaptic growth at neuromuscular junctionGO:005112410.016
cellular response to glucose stimulusGO:0071333650.016
glucose homeostasisGO:0042593750.016
regulation of homotypic cell cell adhesionGO:003411040.015
response to peptide hormoneGO:00434342780.015
secretion by cellGO:00329402480.015
positive regulation of protein metabolic processGO:00512471780.015
regulation of neuron projection developmentGO:00109751610.015
actin filament based processGO:0030029860.015
leukocyte homeostasisGO:000177670.015
response to estradiolGO:00323551640.015
single organism cellular localizationGO:19025801020.015
anterior posterior pattern specificationGO:000995210.015
cellular response to acid chemicalGO:0071229750.015
muscle system processGO:00030121150.015
regulation of peptidase activityGO:0052547550.015
regulation of signal transductionGO:00099663180.015
regulation of protein modification processGO:00313991940.015
sensory perceptionGO:00076001010.015
regulation of t cell activationGO:0050863230.015
sequestering of metal ionGO:005123890.015
organic substance catabolic processGO:19015753160.015
tissue remodelingGO:0048771400.015
reactive nitrogen species metabolic processGO:200105710.015
cell growthGO:00160491040.015
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555130.015
negative regulation of cell communicationGO:00106481580.015
ion homeostasisGO:00508012120.015
regulation of cellular extravasationGO:000269120.015
ovulation cycleGO:0042698670.014
response to interleukin 1GO:0070555550.014
antigen processing and presentation of peptide antigenGO:004800220.014
carbohydrate homeostasisGO:0033500750.014
regulation of cytoskeleton organizationGO:0051493490.014
purine containing compound biosynthetic processGO:0072522850.014
gland developmentGO:00487321550.014
regulation of nucleotide metabolic processGO:00061401170.014
regulation of mapk cascadeGO:00434081160.014
response to toxic substanceGO:00096361330.014
response to transforming growth factor betaGO:0071559460.014
negative regulation of cellular component organizationGO:0051129830.014
positive regulation of ion transportGO:0043270940.014
defense response to gram negative bacteriumGO:005082930.014
response to calcium ionGO:0051592590.014
Human
wound healingGO:00420601220.014
olfactory behaviorGO:004204820.013
transcription from rna polymerase ii promoterGO:00063662520.013
positive regulation of cell projection organizationGO:00313461110.013
cellular response to organonitrogen compoundGO:00714171970.013
regulation of transmembrane transporter activityGO:0022898490.013
regulation of vesicle mediated transportGO:0060627810.013
tube developmentGO:0035295890.013
acute inflammatory responseGO:0002526580.013
negative regulation of phosphate metabolic processGO:0045936800.013
monovalent inorganic cation transportGO:00156721720.013
organic acid biosynthetic processGO:0016053830.013
response to amino acidGO:0043200750.013
cell cell signaling involved in cell fate commitmentGO:004516820.013
sexual reproductionGO:00199531480.013
rna metabolic processGO:00160704060.013
ribonucleoside metabolic processGO:00091191740.013
circulatory system processGO:00030131830.013
cellular response to hormone stimulusGO:00328702470.013
olfactory learningGO:000835510.013
regulation of anatomical structure morphogenesisGO:00226031410.013
negative regulation of nucleobase containing compound metabolic processGO:00459341530.013
regulation of ion transportGO:00432692450.013
protein activation cascadeGO:0072376120.013
somatic diversification of immunoglobulins involved in immune responseGO:000220810.013
negative regulation of response to stimulusGO:00485851550.013
taxisGO:0042330670.013
negative regulation of homeostatic processGO:0032845470.013
response to progesteroneGO:0032570480.013
maintenance of locationGO:0051235170.012
axis specificationGO:000979840.012
carbohydrate derivative biosynthetic processGO:19011371240.012
organic cyclic compound catabolic processGO:19013611750.012
response to dexamethasoneGO:0071548490.012
regulation of transporter activityGO:0032409500.012
release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001480840.012
multicellular organismal signalingGO:0035637440.012
response to estrogenGO:00436272320.012
calcium ion homeostasisGO:00550741620.012
spindle organizationGO:000705120.012
developmental process involved in reproductionGO:00030061590.012
oxidation reduction processGO:00551143040.012
urogenital system developmentGO:0001655780.012
protein polymerizationGO:0051258220.012
regulation of purine nucleotide metabolic processGO:19005421150.012
muscle cell proliferationGO:0033002840.012
regulation of proteolysisGO:0030162660.012
establishment of protein localizationGO:00451841410.012
purine ribonucleotide metabolic processGO:00091502270.012
negative regulation of cell activationGO:0050866150.012
regulation of b cell mediated immunityGO:000271220.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
signal transduction by phosphorylationGO:00230141440.012
cellular response to nitrogen compoundGO:19016992100.012
cellular process involved in reproduction in multicellular organismGO:0022412350.012
purine containing compound catabolic processGO:00725231380.012
regulation of endopeptidase activityGO:0052548510.011
negative regulation of innate immune responseGO:004582440.011
regulation of cell morphogenesisGO:0022604770.011
positive regulation of neuron differentiationGO:00456661260.011
positive regulation of cellular component biogenesisGO:0044089550.011
response to retinoic acidGO:0032526630.011
response to mechanical stimulusGO:00096121340.011
actin filament bundle organizationGO:0061572190.011
neuronal action potentialGO:0019228350.011
positive regulation of protein phosphorylationGO:00019341350.011
purine nucleoside metabolic processGO:00422781690.011
dna metabolic processGO:0006259960.011
protein oligomerizationGO:00512591910.011
cellular response to ketoneGO:1901655510.011
ribonucleoside triphosphate metabolic processGO:00091991410.011
regulation of cellular localizationGO:00603412630.011
rho protein signal transductionGO:0007266110.011
positive regulation of protein modification processGO:00314011420.011
regulation of locomotionGO:00400121480.011
positive regulation of secretion by cellGO:19035321280.011
peptidyl tyrosine modificationGO:0018212720.011
nucleoside phosphate catabolic processGO:19012921400.011
p38mapk cascadeGO:003806610.011
neuron deathGO:00709971270.011
regulation of rna biosynthetic processGO:20011413810.011
cognitionGO:0050890920.011
cell morphogenesisGO:00009021420.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
autophagic cell deathGO:004810240.011
lipid storageGO:001991510.011
hepaticobiliary system developmentGO:0061008900.011
response to fatty acidGO:0070542650.010
negative regulation of growthGO:0045926370.010
intrinsic apoptotic signaling pathway in response to dna damageGO:000863010.010
protein processingGO:0016485680.010
mononuclear cell proliferationGO:0032943290.010
response to osmotic stressGO:0006970420.010
regulation of platelet activationGO:001054320.010
salivary gland developmentGO:000743130.010
signal releaseGO:00230611450.010
cell cell junction organizationGO:0045216200.010
sensory perception of painGO:0019233730.010
regulation of body fluid levelsGO:0050878900.010
lymphocyte proliferationGO:0046651290.010
positive regulation of ion transmembrane transportGO:0034767240.010
stress activated protein kinase signaling cascadeGO:0031098370.010
axon developmentGO:0061564960.010
negative regulation of lymphocyte activationGO:0051250100.010
regulation of transcription from rna polymerase ii promoterGO:00063572340.010
negative regulation of neuron projection developmentGO:0010977460.010
nucleoside triphosphate metabolic processGO:00091411440.010
cyclic nucleotide biosynthetic processGO:0009190630.010
cellular divalent inorganic cation homeostasisGO:00725031620.010

Alox5ap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:1700.046
connective tissue diseaseDOID:6500.046
disease of anatomical entityDOID:700.046
Human
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
nervous system diseaseDOID:86300.012
immune system diseaseDOID:291400.012