Rattus norvegicus

5 known processes

Cyp8b1

cytochrome P450, family 8, subfamily b, polypeptide 1

Cyp8b1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cell proliferationGO:00421273590.550
positive regulation of cellular biosynthetic processGO:00313282950.238
chemical homeostasisGO:00488782920.235
Rat
regulation of programmed cell deathGO:00430673410.229
response to oxygen levelsGO:00704822650.225
Rat
homeostatic processGO:00425923310.189
Rat
apoptotic processGO:00069153810.184
response to hypoxiaGO:00016662310.158
Rat
carboxylic acid biosynthetic processGO:0046394830.149
Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.145
g protein coupled receptor signaling pathwayGO:00071862420.143
response to woundingGO:00096112540.139
response to estrogenGO:00436272320.129
regulation of apoptotic processGO:00429813350.128
response to decreased oxygen levelsGO:00362932370.126
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.126
response to estradiolGO:00323551640.126
programmed cell deathGO:00125013920.125
protein oligomerizationGO:00512591910.116
blood circulationGO:00080151830.108
positive regulation of biosynthetic processGO:00098913190.106
head developmentGO:00603222470.106
single organism reproductive processGO:00447022970.103
circulatory system processGO:00030131830.102
regulation of multicellular organismal developmentGO:20000263760.100
macromolecular complex subunit organizationGO:00439333390.099
single organism biosynthetic processGO:00447113420.099
Rat
cellular homeostasisGO:00197252520.097
organic acid biosynthetic processGO:0016053830.097
Rat
cellular response to lipidGO:00713962010.097
Rat
cellular chemical homeostasisGO:00550822470.096
positive regulation of macromolecule biosynthetic processGO:00105572470.095
cellular response to nitrogen compoundGO:19016992100.094
negative regulation of cell proliferationGO:00082851190.094
cell migrationGO:00164771970.089
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.085
mapk cascadeGO:00001651400.083
positive regulation of cytosolic calcium ion concentrationGO:00072041220.083
response to nutrient levelsGO:00316673700.082
positive regulation of cell proliferationGO:00082842490.081
neuron deathGO:00709971270.080
regulation of ion transportGO:00432692450.079
multicellular organismal reproductive processGO:00486092330.075
positive regulation of rna biosynthetic processGO:19026801970.073
response to bacteriumGO:00096172000.073
cellular metal ion homeostasisGO:00068751720.072
ion homeostasisGO:00508012120.072
positive regulation of rna metabolic processGO:00512542030.071
positive regulation of nucleic acid templated transcriptionGO:19035081970.069
reproductionGO:00000032450.069
regulation of rna metabolic processGO:00512523910.069
negative regulation of multicellular organismal processGO:00512412030.068
cytosolic calcium ion homeostasisGO:00514801400.067
negative regulation of cell deathGO:00605482290.067
transcription from rna polymerase ii promoterGO:00063662520.066
positive regulation of developmental processGO:00510942830.066
locomotionGO:00400112370.066
signal transduction by phosphorylationGO:00230141440.065
regulation of nucleic acid templated transcriptionGO:19035063800.064
cellular response to endogenous stimulusGO:00714953770.064
positive regulation of cell communicationGO:00106472710.062
choline transportGO:001587140.059
response to biotic stimulusGO:00096072260.059
cellular response to organic cyclic compoundGO:00714072020.057
Rat
positive regulation of transcription dna templatedGO:00458931970.056
regulation of secretionGO:00510462240.055
positive regulation of cell differentiationGO:00455972170.054
multi organism reproductive processGO:00447032620.054
regulation of cell developmentGO:00602842630.053
negative regulation of developmental processGO:00510931250.053
positive regulation of cellular component organizationGO:00511302000.053
cellular cation homeostasisGO:00300031800.053
response to organophosphorusGO:00466831020.053
Rat
epithelial cell proliferationGO:0050673540.052
cellular component assemblyGO:00226073600.052
regulation of anatomical structure sizeGO:00900661350.052
positive regulation of gene expressionGO:00106282440.051
learning or memoryGO:0007611900.051
Rat
regulation of cellular component organizationGO:00511283680.051
response to extracellular stimulusGO:00099913800.051
cation transportGO:00068123820.050
macromolecular complex assemblyGO:00650032730.050
immune system processGO:00023762040.050
regulation of cell differentiationGO:00455953200.050
cellular ion homeostasisGO:00068731840.050
response to nutrientGO:00075842480.049
regulation of blood vessel sizeGO:0050880890.049
neuron projection developmentGO:00311752730.048
regulation of catalytic activityGO:00507903040.048
carnitine transportGO:001587910.048
fibrinolysisGO:004273020.048
regulation of neurogenesisGO:00507672470.048
protein phosphorylationGO:00064683450.047
response to ethanolGO:00454711620.047
response to external biotic stimulusGO:00432072210.047
cardiovascular system developmentGO:00723581340.047
positive regulation of neurogenesisGO:00507691650.046
cellular response to hormone stimulusGO:00328702470.046
regulation of cellular protein metabolic processGO:00322682670.046
nitrogen compound transportGO:00717052290.046
carboxylic acid transportGO:00469421150.046
renal system developmentGO:0072001670.045
response to mechanical stimulusGO:00096121340.045
positive regulation of cell migrationGO:0030335960.045
urogenital system developmentGO:0001655780.044
cellular divalent inorganic cation homeostasisGO:00725031620.044
rna metabolic processGO:00160704060.044
neuron developmentGO:00486662860.043
single organism organelle organizationGO:19025891800.043
regulation of protein metabolic processGO:00512462890.043
regulation of system processGO:00440572080.043
reproductive processGO:00224143720.043
positive regulation of apoptotic processGO:00430651540.043
neuron differentiationGO:00301823680.042
positive regulation of nervous system developmentGO:00519621780.042
cellular calcium ion homeostasisGO:00068741600.042
regulation of transcription dna templatedGO:00063553740.042
agingGO:00075682410.042
regulation of neuron deathGO:19012141150.042
positive regulation of cell developmentGO:00107201760.041
cellular amine metabolic processGO:0044106380.041
organelle organizationGO:00069962660.040
calcium ion homeostasisGO:00550741620.040
response to other organismGO:00517072200.040
regulation of cellular ketone metabolic processGO:0010565270.040
Rat
cellular component biogenesisGO:00440853680.039
smooth muscle cell proliferationGO:0048659770.039
regulation of neuron projection developmentGO:00109751610.039
negative regulation of metabolic processGO:00098923310.038
protein complex subunit organizationGO:00718223020.038
response to cocaineGO:0042220390.038
tissue developmentGO:00098882520.038
amine metabolic processGO:0009308380.037
multicellular organism reproductionGO:00325042330.037
positive regulation of extracellular matrix constituent secretionGO:000333120.037
regulation of transcription from rna polymerase ii promoterGO:00063572340.037
transcription dna templatedGO:00063513770.037
cellular response to oxygen containing compoundGO:19017013860.036
Rat
positive regulation of multicellular organismal processGO:00512403870.036
cell motilityGO:00488702020.036
transmembrane transportGO:00550854120.036
regulation of amine transportGO:0051952540.036
regulation of nervous system developmentGO:00519602640.035
glutathione transportGO:003463520.035
response to growth factorGO:00708481890.035
brain developmentGO:00074202470.035
regulation of neuron differentiationGO:00456642080.034
tube developmentGO:0035295890.034
kidney developmentGO:0001822670.034
divalent inorganic cation homeostasisGO:00725071650.034
regulation of protein modification processGO:00313991940.033
response to lipopolysaccharideGO:00324961910.033
response to monosaccharideGO:00342841590.033
oligopeptide transportGO:000685740.033
regulation of epithelial cell proliferationGO:0050678490.032
regulation of kinase activityGO:00435491170.032
organonitrogen compound biosynthetic processGO:19015661670.032
positive regulation of phosphate metabolic processGO:00459372620.032
positive regulation of hormone secretionGO:0046887650.032
behaviorGO:00076102050.032
Rat
catecholamine transportGO:0051937370.032
organic acid transportGO:00158491160.031
response to molecule of bacterial originGO:00022371940.031
positive regulation of programmed cell deathGO:00430681570.031
regulation of rna biosynthetic processGO:20011413810.031
nucleic acid templated transcriptionGO:00976593790.031
regulation of anatomical structure morphogenesisGO:00226031410.031
dna metabolic processGO:0006259960.030
positive regulation of immune system processGO:0002684900.030
alpha amino acid metabolic processGO:1901605710.030
negative regulation of macromolecule metabolic processGO:00106052600.030
positive regulation of phosphorylationGO:00423271770.029
synaptic transmissionGO:00072682350.029
oxoacid metabolic processGO:00434362900.029
Rat
intracellular signal transductionGO:00355563140.029
sterol homeostasisGO:005509230.029
Rat
regulation of phosphate metabolic processGO:00192203490.029
rna biosynthetic processGO:00327743800.029
inflammatory responseGO:00069541500.028
regulation of molecular functionGO:00650093980.028
carboxylic acid metabolic processGO:00197522890.028
Rat
secretionGO:00469033070.028
regulation of inflammatory responseGO:0050727480.028
sodium independent organic anion transportGO:004325220.027
neuron neuron synaptic transmissionGO:0007270600.027
circulatory system developmentGO:00723591340.027
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.027
response to carbohydrateGO:00097431830.026
hormone transportGO:00099141210.026
vascular process in circulatory systemGO:0003018960.026
neurological system processGO:00508772190.026
Rat
cation homeostasisGO:00550801950.026
response to acid chemicalGO:00011012220.026
regulation of response to woundingGO:1903034690.025
catabolic processGO:00090563510.025
Rat
positive regulation of transportGO:00510502450.025
organic hydroxy compound transportGO:0015850770.025
regulation of extracellular matrix constituent secretionGO:000333020.025
anatomical structure morphogenesisGO:00096532980.025
organophosphate metabolic processGO:00196373700.025
regulation of phosphorus metabolic processGO:00511743490.025
negative regulation of protein metabolic processGO:00512481140.025
regulation of smooth muscle cell proliferationGO:0048660750.025
muscle cell proliferationGO:0033002840.025
negative regulation of cellular protein metabolic processGO:00322691060.024
small molecule catabolic processGO:0044282590.024
Rat
response to purine containing compoundGO:00140741260.024
Rat
negative regulation of programmed cell deathGO:00430691830.024
regulation of neurological system processGO:0031644430.024
monocarboxylic acid biosynthetic processGO:0072330480.024
Rat
cellular response to stressGO:00335542690.024
regulation of hydrolase activityGO:00513361430.023
positive regulation of protein metabolic processGO:00512471780.023
regulation of phosphorylationGO:00423252480.023
positive regulation of mapk cascadeGO:0043410920.023
positive regulation of cell deathGO:00109421840.023
positive regulation of signalingGO:00230562700.023
organophosphate biosynthetic processGO:00904071430.022
positive regulation of neuron projection developmentGO:0010976990.022
memoryGO:0007613540.022
Rat
central nervous system developmentGO:00074173110.022
positive regulation of protein modification processGO:00314011420.022
erk1 and erk2 cascadeGO:0070371480.022
actin cytoskeleton organizationGO:0030036730.022
organic acid metabolic processGO:00060822920.022
Rat
negative regulation of cellular metabolic processGO:00313242810.022
cell projection organizationGO:00300303020.022
monoamine transportGO:0015844430.022
regulation of erk1 and erk2 cascadeGO:0070372410.021
epithelium developmentGO:0060429960.021
regulation of intracellular signal transductionGO:19025312180.021
cell cell signalingGO:00072673350.021
response to glucoseGO:00097491360.021
negative regulation of gene expressionGO:00106291990.020
positive regulation of neuron differentiationGO:00456661260.020
ovulation cycleGO:0042698670.020
positive regulation of phosphorus metabolic processGO:00105622620.020
regulation of plasminogen activationGO:001075520.020
negative regulation of signalingGO:00230571570.020
regulation of tube sizeGO:0035150890.020
response to ammonium ionGO:0060359710.020
endocrine processGO:0050886320.019
metal ion homeostasisGO:00550651860.019
sensory perceptionGO:00076001010.019
protein complex assemblyGO:00064612630.019
bile acid biosynthetic processGO:000669930.019
Rat
innate immune responseGO:0045087350.019
negative regulation of neuron deathGO:1901215690.019
lipid biosynthetic processGO:00086101280.019
Rat
regulation of cell migrationGO:00303341280.019
positive regulation of cellular protein metabolic processGO:00322701670.019
multi multicellular organism processGO:00447061380.019
positive regulation of homeostatic processGO:0032846490.019
proteolysisGO:00065081750.019
organic anion transportGO:00157111320.019
anion transportGO:00068201780.019
growthGO:00400071650.019
reproductive system developmentGO:00614581280.019
fatty acid metabolic processGO:0006631990.019
Rat
response to hexoseGO:00097461440.019
regulation of signal transductionGO:00099663180.019
immune responseGO:00069551040.019
response to glucocorticoidGO:00513842230.019
response to molecule of fungal originGO:000223830.018
localization of cellGO:00516742020.018
lipid metabolic processGO:00066292830.018
Rat
negative regulation of calcium ion importGO:009028120.018
positive regulation of intracellular signal transductionGO:19025331380.018
small molecule biosynthetic processGO:00442831240.018
Rat
muscle structure developmentGO:0061061870.018
positive regulation of signal transductionGO:00099671750.018
response to transition metal nanoparticleGO:19902671220.018
sex differentiationGO:00075481130.018
developmental process involved in reproductionGO:00030061590.018
nucleobase containing small molecule metabolic processGO:00550863160.018
alcohol metabolic processGO:0006066770.018
Rat
regulation of immune system processGO:00026821230.018
positive regulation of cell projection organizationGO:00313461110.017
regulation of response to external stimulusGO:00321011060.017
feeding behaviorGO:0007631530.017
divalent inorganic cation transportGO:00725111340.017
positive regulation of secretionGO:00510471400.017
sexual reproductionGO:00199531480.017
cellular response to growth factor stimulusGO:00713631620.017
regenerationGO:00310991630.017
cellular component movementGO:00069282480.017
tongue morphogenesisGO:004358730.017
cholesterol homeostasisGO:004263230.017
Rat
monocarboxylic acid transportGO:0015718520.017
regulation of dna metabolic processGO:0051052600.016
positive regulation of blood circulationGO:1903524650.016
divalent metal ion transportGO:00708381320.016
regulation of metal ion transportGO:00109591180.016
protein maturationGO:0051604680.016
quaternary ammonium group transportGO:001569760.016
hormone secretionGO:00468791150.016
angiogenesisGO:0001525530.016
regulation of protein phosphorylationGO:00019321830.016
antibiotic transportGO:004289120.016
striated muscle tissue developmentGO:0014706580.016
reproductive structure developmentGO:00486081280.016
response to chromateGO:004668730.016
cofactor metabolic processGO:0051186950.016
dopamine transportGO:0015872180.016
cellular response to organonitrogen compoundGO:00714171970.016
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.016
nucleoside phosphate metabolic processGO:00067532830.015
glucose homeostasisGO:0042593750.015
smooth muscle cell migrationGO:0014909360.015
regulation of calcium ion transportGO:0051924770.015
cell type specific apoptotic processGO:00972851340.015
negative regulation of catalytic activityGO:00430861030.015
female pregnancyGO:00075651220.015
purine ribonucleotide metabolic processGO:00091502270.015
regulation of cellular amino acid metabolic processGO:000652120.015
regulation of growthGO:00400081050.015
regulation of transferase activityGO:00513381230.015
calcium ion transportGO:00068161310.015
cellular response to glucocorticoid stimulusGO:0071385680.015
regulation of cellular component movementGO:00512701500.015
single organism behaviorGO:00447081300.015
Rat
salivary gland developmentGO:000743130.015
regulation of secretion by cellGO:19035302080.014
activation of protein kinase activityGO:0032147470.014
positive regulation of cellular amino acid metabolic processGO:004576410.014
regulation of fibrinolysisGO:005191720.014
blood vessel developmentGO:0001568690.014
maintenance of locationGO:0051235170.014
regulation of lipid metabolic processGO:0019216680.014
Rat
response to alkaloidGO:00432791320.014
response to vitamin aGO:0033189360.014
negative regulation of cell communicationGO:00106481580.014
single organism intracellular transportGO:19025821660.014
response to corticosteroidGO:00319602350.014
cellular amino acid metabolic processGO:00065201070.014
negative regulation of molecular functionGO:00440921330.014
female sex differentiationGO:0046660590.014
positive regulation of protein phosphorylationGO:00019341350.014
regulation of cell projection organizationGO:00313441750.014
circadian rhythmGO:0007623880.014
Rat
vesicle mediated transportGO:00161921810.014
positive regulation of extracellular matrix organizationGO:190305540.013
carbohydrate homeostasisGO:0033500750.013
negative regulation of transportGO:00510511360.013
transmission of nerve impulseGO:0019226420.013
cytosolic calcium ion transportGO:0060401390.013
plasminogen activationGO:003163920.013
regulation of blood circulationGO:19035221100.013
carbohydrate derivative metabolic processGO:19011353460.013
regulation of hormone secretionGO:00468831060.013
carbohydrate metabolic processGO:00059751300.013
protein homooligomerizationGO:0051260910.013
regulation of locomotionGO:00400121480.013
digestive tract developmentGO:0048565390.013
multicellular organismal signalingGO:0035637440.013
hormone mediated signaling pathwayGO:0009755230.013
tripeptide transportGO:004293920.013
regulation of ion homeostasisGO:2000021630.013
heart developmentGO:0007507720.013
reactive oxygen species metabolic processGO:0072593370.013
positive regulation of response to stimulusGO:00485842850.013
muscle system processGO:00030121150.013
ion transmembrane transportGO:00342203650.013
rhythmic processGO:00485111560.013
Rat
response to retinoic acidGO:0032526630.013
negative regulation of apoptotic processGO:00430661810.013
defecationGO:003042110.013
steroid metabolic processGO:0008202730.013
Rat
response to inorganic substanceGO:00100353770.013
positive regulation of blood coagulationGO:003019440.013
connective tissue developmentGO:0061448330.013
response to nicotineGO:0035094510.013
leukocyte cell cell adhesionGO:000715940.013
metal ion transportGO:00300012890.013
cellular response to abiotic stimulusGO:0071214850.013
ribose phosphate metabolic processGO:00196932350.012
nucleotide metabolic processGO:00091172790.012
regulation of immunoglobulin productionGO:000263740.012
defense responseGO:00069521940.012
positive regulation of catalytic activityGO:00430851840.012
negative regulation of cell differentiationGO:0045596990.012
action potentialGO:0001508540.012
response to ketoneGO:19016541820.012
regulation of leukocyte activationGO:0002694450.012
cyclic nucleotide metabolic processGO:0009187800.012
sequestering of calcium ionGO:005120880.012
multicellular organismal homeostasisGO:0048871490.012
response to peptide hormoneGO:00434342780.012
lymphocyte proliferationGO:0046651290.012
cellular response to steroid hormone stimulusGO:0071383930.012
regulation of mapk cascadeGO:00434081160.012
epithelial cell differentiationGO:0030855710.012
cytoplasmic transportGO:00164821150.012
response to cytokineGO:00340972150.012
embryonic limb morphogenesisGO:003032640.012
gonad developmentGO:00084061040.012
regulation of body fluid levelsGO:0050878900.012
positive regulation of smooth muscle cell proliferationGO:0048661510.012
organic hydroxy compound metabolic processGO:19016151150.012
Rat
ribonucleotide metabolic processGO:00092592310.012
digestive system developmentGO:0055123410.012
lipid storageGO:001991510.012
regulation of cellular amine metabolic processGO:003323880.011
peristalsisGO:003043220.011
cell cycleGO:00070491010.011
regulation of activation of jak2 kinase activityGO:001053410.011
blood vessel morphogenesisGO:0048514580.011
artery smooth muscle contractionGO:001482440.011
serotonin transportGO:000683790.011
regulation of homeostatic processGO:00328441010.011
vasoconstrictionGO:0042310540.011
intracellular transportGO:00469071850.011
amine transportGO:0015837570.011
isoprenoid metabolic processGO:0006720450.011
cellular response to acid chemicalGO:0071229750.011
cofactor biosynthetic processGO:0051188280.011
mitochondrial fragmentation involved in apoptotic processGO:004365320.011
response to campGO:0051591910.011
Rat
multicellular organismal macromolecule metabolic processGO:0044259210.011
positive regulation of cellular component movementGO:00512721020.011
cellular response to hexose stimulusGO:0071331650.011
ras protein signal transductionGO:0007265290.011
regulation of cell growthGO:0001558850.011
positive regulation of smooth muscle cell migrationGO:0014911270.011
positive regulation of secretion by cellGO:19035321280.011
cellular response to alcoholGO:0097306870.011
Rat
negative regulation of smooth muscle cell proliferationGO:0048662210.011
cellular lipid metabolic processGO:00442552080.011
Rat
anion transmembrane transportGO:0098656770.011
negative regulation of endopeptidase activityGO:0010951360.011
regulation of protein processingGO:0070613500.011
response to vitaminGO:00332731310.011
multicellular organismal response to stressGO:0033555250.011
hepatocyte proliferationGO:007257430.011
regulation of vasculature developmentGO:1901342440.011
small gtpase mediated signal transductionGO:0007264360.011
fatty acid transportGO:0015908250.010
angiotensin mediated drinking behaviorGO:000305120.010
positive regulation of transferase activityGO:0051347810.010
norepinephrine transportGO:0015874180.010
regulation of membrane potentialGO:00423911100.010
nucleoside phosphate biosynthetic processGO:19012931020.010
negative regulation of phosphate metabolic processGO:0045936800.010
regulation of purine nucleotide metabolic processGO:19005421150.010
regulation of peptide transportGO:0090087870.010
gland developmentGO:00487321550.010
positive regulation of lymphocyte activationGO:0051251250.010
extracellular matrix constituent secretionGO:007027840.010
eating behaviorGO:0042755210.010
positive regulation of reactive oxygen species metabolic processGO:2000379160.010
neurotransmitter uptakeGO:000150430.010
regulation of endopeptidase activityGO:0052548510.010
gamete generationGO:00072761240.010
positive regulation of cellular amine metabolic processGO:003324030.010
anatomical structure formation involved in morphogenesisGO:0048646830.010
developmental inductionGO:003112820.010

Cyp8b1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.036
inherited metabolic disorderDOID:65500.021
disease of anatomical entityDOID:700.019
nervous system diseaseDOID:86300.019
disease of cellular proliferationDOID:1456600.013
organ system cancerDOID:005068600.010
cancerDOID:16200.010