Rattus norvegicus

47 known processes

Slc22a1

solute carrier family 22 (organic cation transporter), member 1

(Aliases: Roct1,MGC93570,Orct1,Oct1)

Slc22a1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nutrient levelsGO:00316673700.651
choline transportGO:001587140.489
Rat
cellular component assemblyGO:00226073600.460
cellular response to endogenous stimulusGO:00714953770.421
response to extracellular stimulusGO:00099913800.416
organic acid transportGO:00158491160.377
Rat
protein complex biogenesisGO:00702712630.350
vitamin d receptor signaling pathwayGO:007056110.326
response to nutrientGO:00075842480.309
protein complex assemblyGO:00064612630.307
response to organophosphorusGO:00466831020.298
response to carbohydrateGO:00097431830.269
response to toxic substanceGO:00096361330.267
cellular response to organic cyclic compoundGO:00714072020.267
positive regulation of phagocytosis engulfmentGO:006010040.262
macromolecular complex assemblyGO:00650032730.260
cellular response to hormone stimulusGO:00328702470.259
response to monosaccharideGO:00342841590.250
protein homooligomerizationGO:0051260910.244
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.232
cellular response to oxygen containing compoundGO:19017013860.227
protein oligomerizationGO:00512591910.222
carboxylic acid transportGO:00469421150.210
Rat
antibiotic transportGO:004289120.206
Rat
carboxylic acid metabolic processGO:00197522890.205
tripeptide transportGO:004293920.196
Rat
cellular response to stressGO:00335542690.195
macromolecular complex subunit organizationGO:00439333390.193
brain developmentGO:00074202470.189
response to estradiolGO:00323551640.184
response to estrogenGO:00436272320.181
positive regulation of apoptotic processGO:00430651540.179
protein complex subunit organizationGO:00718223020.178
oxoacid metabolic processGO:00434362900.178
response to metforminGO:190155810.177
pancreatic stellate cell proliferationGO:007234320.177
amino acid transportGO:0006865700.173
Rat
vitamin a metabolic processGO:000677620.162
response to hexoseGO:00097461440.160
regulation of phagocytosis engulfmentGO:006009940.155
response to bacteriumGO:00096172000.151
response to cytokineGO:00340972150.148
response to peptideGO:19016522920.146
cellular response to organonitrogen compoundGO:00714171970.144
response to other organismGO:00517072200.144
Rat
locomotionGO:00400112370.144
cell cell signalingGO:00072673350.143
response to corticosteroidGO:00319602350.143
response to external biotic stimulusGO:00432072210.142
Rat
organic acid metabolic processGO:00060822920.142
cation transportGO:00068123820.140
homeostatic processGO:00425923310.138
response to campGO:0051591910.137
head developmentGO:00603222470.137
regulation of neurogenesisGO:00507672470.136
response to hypoxiaGO:00016662310.129
reproductive processGO:00224143720.129
response to acid chemicalGO:00011012220.127
Rat
response to purine containing compoundGO:00140741260.126
nitrogen compound transportGO:00717052290.124
dicarboxylic acid transportGO:0006835340.122
central nervous system developmentGO:00074173110.121
thioester metabolic processGO:0035383280.120
response to oxygen levelsGO:00704822650.118
negative regulation of nucleobase containing compound metabolic processGO:00459341530.112
regulation of neuron differentiationGO:00456642080.111
negative regulation of transcription dna templatedGO:00458921160.110
negative regulation of cell developmentGO:0010721820.110
cellular response to steroid hormone stimulusGO:0071383930.110
acyl coa metabolic processGO:0006637280.109
regulation of nervous system developmentGO:00519602640.109
single organism biosynthetic processGO:00447113420.109
response to molecule of fungal originGO:000223830.108
Rat
neuron differentiationGO:00301823680.108
regulation of transcription from rna polymerase ii promoterGO:00063572340.107
monocarboxylic acid transportGO:0015718520.106
Rat
single organism reproductive processGO:00447022970.105
cellular component biogenesisGO:00440853680.105
sulfur compound transportGO:007234880.104
Rat
regulation of neuron deathGO:19012141150.104
cellular response to alcoholGO:0097306870.103
reproductive system developmentGO:00614581280.103
transmission of nerve impulseGO:0019226420.100
negative regulation of nitrogen compound metabolic processGO:00511721610.100
gland developmentGO:00487321550.098
cellular ketone metabolic processGO:0042180510.095
glutathione transportGO:003463520.093
Rat
negative regulation of pancreatic stellate cell proliferationGO:200023010.092
negative regulation of multicellular organismal processGO:00512412030.092
female pregnancyGO:00075651220.091
behaviorGO:00076102050.089
response to nicotineGO:0035094510.089
multi multicellular organism processGO:00447061380.088
negative regulation of rna metabolic processGO:00512531230.088
modified amino acid transportGO:0072337120.088
Rat
regulation of cellular component organizationGO:00511283680.087
regulation of multicellular organismal developmentGO:20000263760.087
positive regulation of organic acid transportGO:0032892220.087
catabolic processGO:00090563510.087
drug transmembrane transportGO:0006855130.086
response to radiationGO:00093141370.085
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.083
reproductive structure developmentGO:00486081280.083
regulation of cell developmentGO:00602842630.082
secretionGO:00469033070.082
response to glucoseGO:00097491360.082
organic anion transportGO:00157111320.082
Rat
regenerationGO:00310991630.081
rna biosynthetic processGO:00327743800.079
carboxylic acid catabolic processGO:0046395490.079
chemical homeostasisGO:00488782920.078
fatty acid metabolic processGO:0006631990.077
oligopeptide transportGO:000685740.077
Rat
cellular response to cytokine stimulusGO:00713451270.075
response to vitaminGO:00332731310.075
multicellular organism reproductionGO:00325042330.075
regulation of cell differentiationGO:00455953200.074
response to glucocorticoidGO:00513842230.074
negative regulation of rna biosynthetic processGO:19026791180.074
negative regulation of cellular metabolic processGO:00313242810.073
quaternary ammonium group transportGO:001569760.072
regulation of cellular component movementGO:00512701500.072
circulatory system processGO:00030131830.072
response to mechanical stimulusGO:00096121340.071
telencephalon developmentGO:0021537620.071
regulation of neuron projection developmentGO:00109751610.070
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.069
response to retinoic acidGO:0032526630.069
response to starvationGO:0042594590.068
negative regulation of cellular biosynthetic processGO:00313271610.068
positive regulation of nucleic acid templated transcriptionGO:19035081970.067
oxidation reduction processGO:00551143040.066
developmental process involved in reproductionGO:00030061590.066
acetyl coa metabolic processGO:0006084170.065
response to inorganic substanceGO:00100353770.065
response to peptide hormoneGO:00434342780.065
positive regulation of gene expressionGO:00106282440.064
regulation of cell motilityGO:20001451310.063
response to woundingGO:00096112540.063
transmembrane transportGO:00550854120.062
positive regulation of nitrogen compound metabolic processGO:00511733340.061
response to insulinGO:00328681330.060
anion transportGO:00068201780.059
Rat
cellular response to nitrogen compoundGO:19016992100.059
cellular response to peptideGO:19016531330.059
ion transmembrane transportGO:00342203650.059
neuron developmentGO:00486662860.058
metal ion transportGO:00300012890.058
glucose homeostasisGO:0042593750.058
sulfur compound metabolic processGO:0006790700.058
isoprenoid metabolic processGO:0006720450.058
positive regulation of rna biosynthetic processGO:19026801970.058
response to vitamin dGO:0033280340.057
positive regulation of nucleobase containing compound metabolic processGO:00459353190.057
cellular response to external stimulusGO:00714961180.056
negative regulation of nucleic acid templated transcriptionGO:19035071170.056
regulation of cell projection organizationGO:00313441750.054
negative regulation of response to stimulusGO:00485851550.052
cellular component movementGO:00069282480.052
organophosphate metabolic processGO:00196373700.052
regulation of hormone levelsGO:00108171870.051
negative regulation of developmental processGO:00510931250.051
response to decreased oxygen levelsGO:00362932370.050
neurological system processGO:00508772190.050
dopamine transportGO:0015872180.049
regulation of cellular ketone metabolic processGO:0010565270.048
rhythmic processGO:00485111560.048
positive regulation of transportGO:00510502450.048
positive regulation of biosynthetic processGO:00098913190.047
response to biotic stimulusGO:00096072260.047
Rat
cell motilityGO:00488702020.046
response to amineGO:0014075460.046
anion transmembrane transportGO:0098656770.045
Rat
localization of cellGO:00516742020.045
response to growth factorGO:00708481890.045
cellular response to lipidGO:00713962010.044
negative regulation of nervous system developmentGO:0051961790.044
amide transportGO:00428861050.044
Rat
multicellular organismal signalingGO:0035637440.044
regulation of rna metabolic processGO:00512523910.043
transcription dna templatedGO:00063513770.043
cell projection organizationGO:00300303020.042
response to alkaloidGO:00432791320.042
response to lipopolysaccharideGO:00324961910.042
regulation of cell proliferationGO:00421273590.042
cellular response to ketoneGO:1901655510.042
positive regulation of transcription dna templatedGO:00458931970.041
positive regulation of cellular biosynthetic processGO:00313282950.041
regulation of secretionGO:00510462240.041
development of primary sexual characteristicsGO:00451371070.041
coenzyme metabolic processGO:0006732860.041
signal releaseGO:00230611450.041
cellular response to follicle stimulating hormone stimulusGO:0071372130.041
positive regulation of macromolecule biosynthetic processGO:00105572470.040
fatty acid oxidationGO:0019395290.039
carboxylic acid biosynthetic processGO:0046394830.039
carbohydrate homeostasisGO:0033500750.039
cellular homeostasisGO:00197252520.039
blood circulationGO:00080151830.039
negative regulation of cellular component organizationGO:0051129830.038
single organism catabolic processGO:00447122830.038
cellular response to growth factor stimulusGO:00713631620.038
l glutamate importGO:005193820.037
organic cation transportGO:0015695110.037
response to ethanolGO:00454711620.037
regulation of rna biosynthetic processGO:20011413810.037
protein localizationGO:00081041910.036
cellular amino acid metabolic processGO:00065201070.036
positive regulation of rna metabolic processGO:00512542030.036
positive regulation of cellular component organizationGO:00511302000.036
cellular response to insulin stimulusGO:0032869810.036
positive regulation of locomotionGO:00400171020.036
transcription from rna polymerase ii promoterGO:00063662520.035
protein tetramerizationGO:0051262380.035
aromatic amino acid family catabolic processGO:000907470.035
regulation of peptide hormone secretionGO:0090276800.035
positive regulation of gamma aminobutyric acid secretionGO:001405440.035
regulation of cell growthGO:0001558850.034
regulation of anatomical structure sizeGO:00900661350.034
alpha amino acid metabolic processGO:1901605710.034
tissue developmentGO:00098882520.034
positive regulation of neuron projection developmentGO:0010976990.034
lipid metabolic processGO:00066292830.033
bile acid biosynthetic processGO:000669930.033
cellular response to vitamin eGO:007130630.033
exogenous drug catabolic processGO:004273810.033
muscle cell migrationGO:0014812360.033
acidic amino acid transportGO:0015800100.033
negative regulation of neurogenesisGO:0050768780.032
response to activityGO:0014823730.032
estrogen biosynthetic processGO:000670360.032
multi organism reproductive processGO:00447032620.032
negative regulation of metabolic processGO:00098923310.032
negative regulation of biosynthetic processGO:00098901680.031
vesicle mediated transportGO:00161921810.031
tube developmentGO:0035295890.031
negative regulation of cell proliferationGO:00082851190.030
negative regulation of macromolecule metabolic processGO:00106052600.030
negative regulation of macromolecule biosynthetic processGO:00105581480.030
behavioral response to nicotineGO:003509520.030
negative regulation of telomerase activityGO:005197410.029
regulation of apoptotic processGO:00429813350.029
regulation of insulin secretionGO:0050796650.029
response to corticosteroneGO:0051412400.029
neuron projection developmentGO:00311752730.029
positive regulation of multicellular organismal processGO:00512403870.029
cellular catabolic processGO:00442482950.029
cellular response to cgmpGO:007132120.029
cellular response to extracellular stimulusGO:0031668730.029
sex differentiationGO:00075481130.029
smooth muscle cell migrationGO:0014909360.029
mrna transcriptionGO:000929920.029
response to calcium ionGO:0051592590.029
cellular response to acid chemicalGO:0071229750.028
regulation of programmed cell deathGO:00430673410.028
response to foodGO:0032094270.028
negative regulation of cell differentiationGO:0045596990.028
bile acid and bile salt transportGO:0015721120.028
organic hydroxy compound metabolic processGO:19016151150.028
programmed cell deathGO:00125013920.028
liver developmentGO:0001889900.028
multicellular organismal reproductive processGO:00486092330.028
response to metal ionGO:00100382530.027
regulation of ion transportGO:00432692450.027
regulation of tube sizeGO:0035150890.027
positive regulation of programmed cell deathGO:00430681570.027
response to transition metal nanoparticleGO:19902671220.027
hepaticobiliary system developmentGO:0061008900.027
diterpenoid metabolic processGO:0016101330.027
cellular response to metal ionGO:0071248550.026
response to lead ionGO:0010288330.026
single organism behaviorGO:00447081300.026
drug transportGO:0015893180.026
response to molecule of bacterial originGO:00022371940.026
regulation of secretion by cellGO:19035302080.026
regulation of pancreatic stellate cell proliferationGO:200022920.026
aromatic amino acid family metabolic processGO:000907290.025
response to increased oxygen levelsGO:0036296450.025
regulation of dendrite developmentGO:0050773590.025
regulation of growthGO:00400081050.025
immune system processGO:00023762040.025
embryo implantationGO:0007566150.025
synaptic transmissionGO:00072682350.024
regulation of blood pressureGO:0008217830.024
cellular chemical homeostasisGO:00550822470.024
positive regulation of cell differentiationGO:00455972170.024
regulation of cell migrationGO:00303341280.024
organonitrogen compound biosynthetic processGO:19015661670.024
response to hyperoxiaGO:0055093450.024
digestive system developmentGO:0055123410.023
monosaccharide metabolic processGO:0005996610.023
response to vitamin aGO:0033189360.023
positive regulation of cell projection organizationGO:00313461110.023
monosaccharide transportGO:0015749310.023
cellular response to hexose stimulusGO:0071331650.023
nucleic acid templated transcriptionGO:00976593790.023
cell migrationGO:00164771970.023
apoptotic processGO:00069153810.022
immune responseGO:00069551040.022
cellular response to nutrient levelsGO:0031669600.022
positive regulation of nervous system developmentGO:00519621780.022
cellular response to glucose stimulusGO:0071333650.022
negative regulation of neuron differentiationGO:0045665620.022
reproductionGO:00000032450.022
hexose metabolic processGO:0019318580.022
neuron deathGO:00709971270.021
insulin secretionGO:0030073690.021
response to interleukin 1GO:0070555550.021
nucleoside phosphate metabolic processGO:00067532830.021
neuronal action potentialGO:0019228350.021
regulation of serine type peptidase activityGO:190257110.021
positive regulation of cell migrationGO:0030335960.021
cell growthGO:00160491040.021
neuron projection regenerationGO:0031102350.021
regulation of cellular amino acid metabolic processGO:000652120.020
cofactor metabolic processGO:0051186950.020
positive regulation of cellular amino acid metabolic processGO:004576410.020
epithelium developmentGO:0060429960.020
forebrain developmentGO:0030900980.020
amino acid transmembrane transportGO:0003333330.020
Rat
negative regulation of gene expressionGO:00106291990.020
response to cgmpGO:007030530.020
gamma aminobutyric acid secretionGO:001405160.019
sodium independent organic anion transportGO:004325220.019
Rat
positive regulation of amino acid transportGO:0051957130.019
rna metabolic processGO:00160704060.019
insecticide metabolic processGO:001714340.019
terpenoid metabolic processGO:0006721370.019
cellular response to carbohydrate stimulusGO:0071322720.019
ribonucleotide biosynthetic processGO:0009260850.019
regulation of peptide transportGO:0090087870.019
positive regulation of ion transportGO:0043270940.019
positive regulation of epidermis developmentGO:004568410.019
peptide secretionGO:0002790860.019
cellular response to campGO:0071320260.019
regulation of hormone secretionGO:00468831060.019
small molecule catabolic processGO:0044282590.019
carnitine transportGO:001587910.019
Rat
gonad developmentGO:00084061040.019
agingGO:00075682410.018
axon regenerationGO:0031103280.018
positive regulation of purine nucleotide metabolic processGO:1900544910.018
gastrulationGO:000736920.018
negative regulation of transportGO:00510511360.018
response to follicle stimulating hormoneGO:0032354180.018
retinoid metabolic processGO:0001523240.018
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.018
organic acid catabolic processGO:0016054490.018
axon developmentGO:0061564960.018
regulation of gluconeogenesisGO:000611140.018
cellular glucose homeostasisGO:0001678660.018
response to cocaineGO:0042220390.018
response to axon injuryGO:0048678590.018
calcium ion transportGO:00068161310.018
urogenital system developmentGO:0001655780.018
negative regulation of growthGO:0045926370.018
positive regulation of developmental processGO:00510942830.018
regulation of cellular amine metabolic processGO:003323880.018
cellular response to tumor necrosis factorGO:0071356460.018
regulation of peptide secretionGO:0002791820.017
response to mineralocorticoidGO:0051385490.017
lipid storageGO:001991510.017
cellular carbohydrate metabolic processGO:0044262720.017
posttranscriptional regulation of gene expressionGO:0010608370.017
monocarboxylic acid biosynthetic processGO:0072330480.017
cholesterol homeostasisGO:004263230.017
carbohydrate metabolic processGO:00059751300.017
lateral ventricle developmentGO:002167010.017
organic substance catabolic processGO:19015753160.017
embryonic appendage morphogenesisGO:003511340.017
hormone transportGO:00099141210.017
multicellular organism growthGO:003526410.017
divalent inorganic cation transportGO:00725111340.016
growthGO:00400071650.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.016
regulation of cellular component biogenesisGO:0044087860.016
cellular lipid catabolic processGO:0044242370.016
cellular amine metabolic processGO:0044106380.016
glutamine family amino acid metabolic processGO:0009064150.016
response to amphetamineGO:0001975250.016
placenta developmentGO:0001890220.016
organonitrogen compound catabolic processGO:19015651790.016
locomotor rhythmGO:004547510.016
response to light stimulusGO:0009416520.016
positive regulation of smooth muscle cell migrationGO:0014911270.016
response to vitamin eGO:0033197240.016
maternal process involved in female pregnancyGO:0060135380.016
cellular response to monosaccharide stimulusGO:0071326670.016
positive regulation of peptide hormone secretionGO:0090277500.015
response to osmotic stressGO:0006970420.015
leydig cell differentiationGO:003332780.015
regulation of amino acid transportGO:0051955250.015
divalent metal ion transportGO:00708381320.015
regulation of locomotionGO:00400121480.015
neurotransmitter uptakeGO:000150430.015
positive regulation of neurogenesisGO:00507691650.015
hormone metabolic processGO:0042445690.015
response to potassium ionGO:003586490.015
sterol homeostasisGO:005509230.015
amine metabolic processGO:0009308380.015
glycoside transportGO:190165620.015
defense responseGO:00069521940.015
regulation of vesicle mediated transportGO:0060627810.015
lipid transportGO:0006869610.015
positive regulation of cell motilityGO:2000147970.015
androgen metabolic processGO:0008209140.014
cellular response to inorganic substanceGO:0071241650.014
negative regulation of tyrosine phosphorylation of stat5 proteinGO:004252410.014
positive regulation of cell deathGO:00109421840.014
spermatogenesisGO:0007283990.014
response to ketoneGO:19016541820.014
positive regulation of neuron differentiationGO:00456661260.014
neuron neuron synaptic transmissionGO:0007270600.014
response to blue lightGO:000963710.014
hormone secretionGO:00468791150.014
male sex differentiationGO:0046661640.014
regulation of immune system processGO:00026821230.014
female sex differentiationGO:0046660590.014
defense response to gram negative bacteriumGO:005082930.014
endocytosisGO:0006897840.014
androgen biosynthetic processGO:0006702100.014
monocarboxylic acid catabolic processGO:0072329280.013
response to dexamethasoneGO:0071548490.013
sensory organ developmentGO:0007423740.013
regulation of organic acid transportGO:0032890350.013
cell cycleGO:00070491010.013
cellular amino acid catabolic processGO:0009063210.013
peptide hormone secretionGO:0030072840.013
regulation of cell cycleGO:0051726730.013
positive regulation of catalytic activityGO:00430851840.013
cognitionGO:0050890920.013
organ regenerationGO:00311001010.013
canalicular bile acid transportGO:001572250.013
organic acid biosynthetic processGO:0016053830.013
acid secretionGO:0046717480.013
response to cadmium ionGO:0046686350.013
positive regulation of peptide secretionGO:0002793520.013
cerebellar granule cell precursor proliferationGO:002193010.013
cardiovascular system developmentGO:00723581340.013
olfactory behaviorGO:004204820.012
renal system processGO:0003014400.012
organelle organizationGO:00069962660.012
regulation of fatty acid metabolic processGO:0019217180.012
lipid biosynthetic processGO:00086101280.012
negative regulation of synaptic transmission dopaminergicGO:003222740.012
small gtpase mediated signal transductionGO:0007264360.012
regulation of cellular localizationGO:00603412630.012
regulation of catalytic activityGO:00507903040.012
cell proliferation in external granule layerGO:002192410.012
response to fatty acidGO:0070542650.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
ear developmentGO:0043583210.012
monocarboxylic acid metabolic processGO:00327871520.012
regulation of response to woundingGO:1903034690.012
regulation of lipid metabolic processGO:0019216680.012
action potentialGO:0001508540.012
cellular response to interleukin 1GO:0071347370.012
response to tumor necrosis factorGO:0034612560.012
gamma aminobutyric acid transportGO:001581280.012
ribose phosphate metabolic processGO:00196932350.012
glucose metabolic processGO:0006006520.012
toxin transportGO:190199830.012
Rat
l amino acid transportGO:0015807210.012
cellular response to transforming growth factor beta stimulusGO:0071560410.012
cgmp biosynthetic processGO:0006182150.012
gluconeogenesisGO:0006094150.012
fractalkine metabolic processGO:005075630.012
myelinationGO:0042552390.012
gamete generationGO:00072761240.012
digestive tract developmentGO:0048565390.011
smooth muscle cell proliferationGO:0048659770.011
response to reactive oxygen speciesGO:00003021200.011
positive regulation of amine transportGO:0051954260.011
sexual reproductionGO:00199531480.011
fatty acid biosynthetic processGO:0006633330.011
proteoglycan metabolic processGO:000602930.011
regulation of nucleic acid templated transcriptionGO:19035063800.011
negative regulation of cellular protein metabolic processGO:00322691060.011
t cell tolerance inductionGO:000251730.011
lipid oxidationGO:0034440300.011

Slc22a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.039
inherited metabolic disorderDOID:65500.039
urinary system diseaseDOID:1800.031
disease of anatomical entityDOID:700.031
kidney diseaseDOID:55700.023
nervous system diseaseDOID:86300.019
lipid metabolism disorderDOID:314600.015
steroid inherited metabolic disorderDOID:170100.015
congenital adrenal hyperplasiaDOID:005081100.015
organ system cancerDOID:005068600.012
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
acquired metabolic diseaseDOID:006015800.012
glucose metabolism diseaseDOID:419400.012
carbohydrate metabolism diseaseDOID:005001300.012
musculoskeletal system diseaseDOID:1700.011