Rattus norvegicus

22 known processes

Slc22a2

solute carrier family 22 (organic cation transporter), member 2

(Aliases: rOCT2,OCT2,OCT2r)

Slc22a2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.296
response to organophosphorusGO:00466831020.258
cell cell signalingGO:00072673350.175
amino acid transportGO:0006865700.174
Rat
organic acid metabolic processGO:00060822920.170
gland developmentGO:00487321550.163
g protein coupled receptor signaling pathwayGO:00071862420.154
anion transmembrane transportGO:0098656770.152
Rat
rhythmic processGO:00485111560.149
oxoacid metabolic processGO:00434362900.149
ion transmembrane transportGO:00342203650.148
tissue developmentGO:00098882520.126
response to ethanolGO:00454711620.119
regulation of cell differentiationGO:00455953200.116
regulation of rna metabolic processGO:00512523910.109
reproductive system developmentGO:00614581280.108
regulation of multicellular organismal developmentGO:20000263760.100
single organism reproductive processGO:00447022970.100
response to toxic substanceGO:00096361330.098
positive regulation of programmed cell deathGO:00430681570.098
rna biosynthetic processGO:00327743800.096
programmed cell deathGO:00125013920.095
inorganic ion transmembrane transportGO:00986602290.093
positive regulation of signalingGO:00230562700.091
anion transportGO:00068201780.086
Rat
cellular response to oxygen containing compoundGO:19017013860.084
secretionGO:00469033070.083
regulation of saliva secretionGO:004687730.083
regulation of secretionGO:00510462240.083
protein complex assemblyGO:00064612630.079
Rat
choline transportGO:001587140.078
cation transmembrane transportGO:00986552630.077
negative regulation of ion transportGO:0043271510.073
organelle organizationGO:00069962660.073
head developmentGO:00603222470.071
ovulation cycleGO:0042698670.069
regulation of transmembrane transportGO:00347621220.069
carboxylic acid metabolic processGO:00197522890.066
regulation of cellular ketone metabolic processGO:0010565270.066
positive regulation of developmental processGO:00510942830.066
neurological system processGO:00508772190.065
positive regulation of the force of heart contraction by epinephrine norepinephrineGO:000199720.064
neuron neuron synaptic transmissionGO:0007270600.064
response to other organismGO:00517072200.063
Rat
cellular ketone metabolic processGO:0042180510.060
regulation of cell proliferationGO:00421273590.060
reproductive processGO:00224143720.060
synaptic transmission gabaergicGO:0051932220.059
synaptic transmissionGO:00072682350.059
cellular component biogenesisGO:00440853680.059
Rat
regulation of programmed cell deathGO:00430673410.058
positive regulation of cell communicationGO:00106472710.058
brain developmentGO:00074202470.057
ovulation cycle processGO:0022602500.057
response to ammonium ionGO:0060359710.057
negative regulation of transportGO:00510511360.057
positive regulation of biosynthetic processGO:00098913190.055
response to extracellular stimulusGO:00099913800.055
multicellular organismal reproductive processGO:00486092330.055
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.054
myelinationGO:0042552390.054
transmission of nerve impulseGO:0019226420.053
regulation of cellular localizationGO:00603412630.053
anatomical structure morphogenesisGO:00096532980.052
protein complex biogenesisGO:00702712630.052
Rat
regulation of apoptotic processGO:00429813350.051
positive regulation of phosphorylationGO:00423271770.051
organic anion transportGO:00157111320.050
Rat
cellular amino acid metabolic processGO:00065201070.050
response to nutrientGO:00075842480.050
regulation of phosphorus metabolic processGO:00511743490.049
multicellular organism reproductionGO:00325042330.049
cellular response to nitrogen compoundGO:19016992100.049
cellular amine metabolic processGO:0044106380.048
macromolecular complex subunit organizationGO:00439333390.048
Rat
single organism organelle organizationGO:19025891800.047
neuron developmentGO:00486662860.047
locomotionGO:00400112370.047
saliva secretionGO:004654130.047
negative regulation of developmental processGO:00510931250.046
synaptic transmission glycinergicGO:006001220.046
regulation of organelle organizationGO:0033043800.045
apoptotic processGO:00069153810.045
positive regulation of macromolecule biosynthetic processGO:00105572470.045
response to peptideGO:19016522920.044
regulation of phosphate metabolic processGO:00192203490.044
regulation of cellular amino acid metabolic processGO:000652120.044
agingGO:00075682410.044
organophosphate metabolic processGO:00196373700.044
regulation of nucleic acid templated transcriptionGO:19035063800.044
skeletal system developmentGO:0001501410.043
response to external biotic stimulusGO:00432072210.043
Rat
intracellular signal transductionGO:00355563140.042
secretion by cellGO:00329402480.042
cytoskeleton organizationGO:00070101110.042
organic hydroxy compound metabolic processGO:19016151150.042
developmental process involved in reproductionGO:00030061590.041
transcription dna templatedGO:00063513770.041
reproductionGO:00000032450.041
regulation of cellular amine metabolic processGO:003323880.040
female gonad developmentGO:0008585530.040
regulation of molecular functionGO:00650093980.040
regulation of ion transmembrane transportGO:00347651210.038
urinary tract smooth muscle contractionGO:001484840.038
cellular component assemblyGO:00226073600.038
Rat
organ inductionGO:000175910.038
insecticide metabolic processGO:001714340.037
rna metabolic processGO:00160704060.037
ribonucleotide biosynthetic processGO:0009260850.037
actin filament based processGO:0030029860.037
female sex differentiationGO:0046660590.037
liver developmentGO:0001889900.037
developmental inductionGO:003112820.036
single organism biosynthetic processGO:00447113420.036
urinary bladder smooth muscle contractionGO:001483240.036
purine containing compound metabolic processGO:00725212530.035
positive regulation of secretion by cellGO:19035321280.035
positive regulation of multicellular organismal processGO:00512403870.035
response to estrogenGO:00436272320.035
homeostatic processGO:00425923310.035
macromolecular complex assemblyGO:00650032730.035
Rat
regulation of neurogenesisGO:00507672470.034
sensory organ developmentGO:0007423740.034
response to oxidative stressGO:00069791860.034
reproductive structure developmentGO:00486081280.034
angiogenesis involved in coronary vascular morphogenesisGO:006097830.033
regulation of organ formationGO:000315620.033
negative regulation of multicellular organismal processGO:00512412030.033
nitrogen compound transportGO:00717052290.032
cell type specific apoptotic processGO:00972851340.032
neuron projection developmentGO:00311752730.032
regulation of amine transportGO:0051952540.032
neuron differentiationGO:00301823680.032
sulfur compound transportGO:007234880.032
Rat
telencephalon developmentGO:0021537620.032
ossificationGO:0001503700.032
positive regulation of nucleobase containing compound metabolic processGO:00459353190.031
positive regulation of cellular amino acid metabolic processGO:004576410.031
hepaticobiliary system developmentGO:0061008900.031
mesoderm developmentGO:000749820.031
positive regulation of nitrogen compound metabolic processGO:00511733340.031
multi organism reproductive processGO:00447032620.030
response to biotic stimulusGO:00096072260.030
Rat
positive regulation of cellular biosynthetic processGO:00313282950.030
macromolecule localizationGO:00330362520.029
action potentialGO:0001508540.029
development of primary sexual characteristicsGO:00451371070.029
protein phosphorylationGO:00064683450.029
regulation of nucleotide metabolic processGO:00061401170.029
monoamine transportGO:0015844430.029
Rat
single organism catabolic processGO:00447122830.029
cellular response to endogenous stimulusGO:00714953770.028
regulation of secretion by cellGO:19035302080.028
cellular response to growth factor stimulusGO:00713631620.028
response to peptide hormoneGO:00434342780.028
cation transportGO:00068123820.028
nucleobase containing small molecule metabolic processGO:00550863160.028
positive regulation of cellular component organizationGO:00511302000.028
growthGO:00400071650.027
regulation of cell developmentGO:00602842630.027
actin cytoskeleton organizationGO:0030036730.027
regulation of cellular protein metabolic processGO:00322682670.027
response to estradiolGO:00323551640.027
axon ensheathmentGO:0008366400.027
negative regulation of gene expressionGO:00106291990.027
protein complex subunit organizationGO:00718223020.027
Rat
regulation of synaptic transmissionGO:00508041410.027
nucleic acid templated transcriptionGO:00976593790.026
membrane organizationGO:0061024940.026
enzyme linked receptor protein signaling pathwayGO:00071671160.026
ensheathment of neuronsGO:0007272400.026
amine metabolic processGO:0009308380.026
positive regulation of cell differentiationGO:00455972170.026
positive regulation of cell developmentGO:00107201760.026
cellular response to hormone stimulusGO:00328702470.026
ribose phosphate metabolic processGO:00196932350.026
positive regulation of cellular amine metabolic processGO:003324030.025
regulation of rna biosynthetic processGO:20011413810.025
multicellular organismal signalingGO:0035637440.025
neural crest cell developmentGO:001403220.025
response to metal ionGO:00100382530.025
response to insulinGO:00328681330.025
response to ketoneGO:19016541820.025
cgmp biosynthetic processGO:0006182150.025
response to cytokineGO:00340972150.025
positive regulation of ion transportGO:0043270940.025
regulation of ion transportGO:00432692450.025
cyclic nucleotide biosynthetic processGO:0009190630.024
organonitrogen compound biosynthetic processGO:19015661670.024
female pregnancyGO:00075651220.024
response to corticosteroidGO:00319602350.024
multicellular organismal homeostasisGO:0048871490.024
sodium ion transmembrane transportGO:0035725670.024
sodium ion transportGO:0006814820.024
positive regulation of catalytic activityGO:00430851840.024
dopamine transportGO:0015872180.024
Rat
embryo developmentGO:0009790490.023
protein localizationGO:00081041910.023
negative regulation of cellular biosynthetic processGO:00313271610.023
positive regulation of the force of heart contraction by chemical signalGO:000309920.023
purine ribonucleotide biosynthetic processGO:0009152810.023
positive regulation of neurogenesisGO:00507691650.023
positive regulation of apoptotic processGO:00430651540.022
neuronal action potentialGO:0019228350.022
anterior posterior pattern specificationGO:000995210.022
response to campGO:0051591910.022
central nervous system developmentGO:00074173110.022
blood vessel developmentGO:0001568690.022
regulation of neurotransmitter levelsGO:0001505420.022
amine transportGO:0015837570.022
behaviorGO:00076102050.022
brown fat cell proliferationGO:007034220.022
response to starvationGO:0042594590.022
regulation of sodium ion transportGO:0002028210.022
circulatory system developmentGO:00723591340.022
hormone secretionGO:00468791150.022
response to nutrient levelsGO:00316673700.021
purine nucleotide metabolic processGO:00061632290.021
regulation of hormone levelsGO:00108171870.021
Rat
positive regulation of cell proliferationGO:00082842490.021
regulation of catalytic activityGO:00507903040.021
single organism membrane organizationGO:0044802740.021
cell activationGO:0001775970.021
response to growth factorGO:00708481890.021
positive regulation of hydrolase activityGO:0051345860.021
peptidyl tyrosine phosphorylationGO:0018108720.021
nucleoside phosphate biosynthetic processGO:19012931020.021
positive regulation of synaptic transmissionGO:0050806620.020
response to retinoic acidGO:0032526630.020
connective tissue developmentGO:0061448330.020
neurotransmitter gated ion channel clusteringGO:007257830.020
regulation of nervous system developmentGO:00519602640.020
hindlimb morphogenesisGO:003513720.020
negative regulation of macromolecule metabolic processGO:00106052600.020
regulation of cell growthGO:0001558850.020
lipid biosynthetic processGO:00086101280.019
negative regulation of cell differentiationGO:0045596990.019
response to inorganic substanceGO:00100353770.019
calcium ion importGO:0070509220.019
response to hexoseGO:00097461440.019
inorganic cation transmembrane transportGO:00986622020.019
response to hypoxiaGO:00016662310.019
negative regulation of apoptotic processGO:00430661810.019
amino acid transmembrane transportGO:0003333330.019
Rat
sex differentiationGO:00075481130.019
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.019
acid secretionGO:0046717480.019
heart morphogenesisGO:000300730.019
nucleoside phosphate metabolic processGO:00067532830.018
positive regulation of growthGO:0045927550.018
response to vitaminGO:00332731310.018
response to fungicideGO:0060992200.018
signal releaseGO:00230611450.018
small gtpase mediated signal transductionGO:0007264360.018
regulation of transcription from rna polymerase ii promoterGO:00063572340.018
regulation of neuron apoptotic processGO:0043523830.018
catecholamine transportGO:0051937370.018
Rat
forebrain developmentGO:0030900980.018
organophosphate biosynthetic processGO:00904071430.018
alcohol metabolic processGO:0006066770.018
embryonic appendage morphogenesisGO:003511340.018
response to dexamethasoneGO:0071548490.017
regenerationGO:00310991630.017
development of primary female sexual characteristicsGO:0046545560.017
axis specificationGO:000979840.017
cellular component morphogenesisGO:00329891550.017
cellular response to cytokine stimulusGO:00713451270.017
ras protein signal transductionGO:0007265290.017
carbohydrate derivative metabolic processGO:19011353460.017
positive regulation of nervous system developmentGO:00519621780.017
amide transportGO:00428861050.017
Rat
regulation of dopamine secretionGO:0014059150.017
transcription from rna polymerase ii promoterGO:00063662520.017
cellular response to stressGO:00335542690.017
embryonic skeletal system morphogenesisGO:004870430.017
positive regulation of cellular protein metabolic processGO:00322701670.017
neuron deathGO:00709971270.017
adenylate cyclase inhibiting serotonin receptor signaling pathwayGO:000719810.016
positive regulation of cell motilityGO:2000147970.016
cytoplasmic transportGO:00164821150.016
response to molecule of bacterial originGO:00022371940.016
neurotransmitter transportGO:0006836420.016
Rat
negative regulation of cellular metabolic processGO:00313242810.016
regulation of protein metabolic processGO:00512462890.016
leukocyte activationGO:0045321760.016
carboxylic acid transportGO:00469421150.016
Rat
positive regulation of secretionGO:00510471400.016
regulation of brown fat cell proliferationGO:007034710.016
cellular chemical homeostasisGO:00550822470.016
blood circulationGO:00080151830.016
bone developmentGO:0060348250.016
negative regulation of programmed cell deathGO:00430691830.016
nucleotide biosynthetic processGO:0009165980.016
cellular homeostasisGO:00197252520.016
cellular macromolecule localizationGO:00707271220.016
cellular response to organic cyclic compoundGO:00714072020.016
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.015
regulation of platelet activationGO:001054320.015
positive regulation of phosphorus metabolic processGO:00105622620.015
salivary gland developmentGO:000743130.015
neuron apoptotic processGO:0051402880.015
lipid metabolic processGO:00066292830.015
cell communication involved in cardiac conductionGO:008606520.015
digestionGO:0007586260.015
organic substance catabolic processGO:19015753160.015
ovulationGO:0030728170.015
cardiovascular system developmentGO:00723581340.015
regulation of the force of heart contraction by chemical signalGO:000305720.015
protein homooligomerizationGO:0051260910.015
Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.015
negative regulation of cell deathGO:00605482290.015
cellular lipid metabolic processGO:00442552080.015
limb morphogenesisGO:003510840.015
microtubule based processGO:0007017360.015
ribonucleotide metabolic processGO:00092592310.015
monovalent inorganic cation transportGO:00156721720.015
organic hydroxy compound transportGO:0015850770.015
blood vessel morphogenesisGO:0048514580.015
gonad developmentGO:00084061040.015
hippocampus developmentGO:0021766300.015
regulation of stem cell differentiationGO:200073620.015
fat cell proliferationGO:007034120.014
regulation of protein phosphorylationGO:00019321830.014
response to cocaineGO:0042220390.014
response to lipopolysaccharideGO:00324961910.014
hormone transportGO:00099141210.014
Rat
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.014
regulation of fat cell proliferationGO:007034410.014
positive regulation of cell deathGO:00109421840.014
regulation of smooth muscle cell proliferationGO:0048660750.014
regulation of membrane potentialGO:00423911100.014
regulation of synaptic transmission gabaergicGO:0032228170.014
positive regulation of renin secretion into blood streamGO:190013510.014
ovarian follicle developmentGO:0001541310.014
neural crest cell differentiationGO:001403320.014
cellular response to organonitrogen compoundGO:00714171970.014
secretion by tissueGO:0032941370.014
positive regulation of transportGO:00510502450.014
cell cell signaling involved in cell fate commitmentGO:004516820.014
respiratory system developmentGO:0060541450.014
negative regulation of transcription dna templatedGO:00458921160.014
cation homeostasisGO:00550801950.014
peptidyl amino acid modificationGO:00181931260.014
positive regulation of signal transductionGO:00099671750.014
peptide transportGO:0015833970.014
Rat
regulation of organic acid transportGO:0032890350.014
lung developmentGO:0030324430.014
serotonin receptor signaling pathwayGO:0007210100.014
response to carbohydrateGO:00097431830.014
regulation of intracellular signal transductionGO:19025312180.013
cardiac conductionGO:006133720.013
hormone metabolic processGO:0042445690.013
synapse organizationGO:0050808460.013
positive regulation of molecular functionGO:00440932300.013
nucleotide metabolic processGO:00091172790.013
circadian rhythmGO:0007623880.013
positive regulation of hormone secretionGO:0046887650.013
positive regulation of smooth muscle cell proliferationGO:0048661510.013
peptidyl tyrosine modificationGO:0018212720.013
negative regulation of uterine smooth muscle contractionGO:007047320.013
cell cycleGO:00070491010.013
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.013
negative regulation of nervous system developmentGO:0051961790.013
regulation of action potentialGO:0098900140.013
regulation of nitric oxide synthase activityGO:005099980.013
regulation of anion transportGO:0044070430.013
response to alkaloidGO:00432791320.013
single organism intracellular transportGO:19025821660.012
regulation of homeostatic processGO:00328441010.012
organ morphogenesisGO:0009887750.012
hematopoietic progenitor cell differentiationGO:000224420.012
regulation of transcription dna templatedGO:00063553740.012
gamete generationGO:00072761240.012
negative regulation of neuron differentiationGO:0045665620.012
response to oxygen levelsGO:00704822650.012
positive regulation of cyclic nucleotide metabolic processGO:0030801370.012
sexual reproductionGO:00199531480.012
regulation of metal ion transportGO:00109591180.012
salivary gland morphogenesisGO:000743510.012
monocarboxylic acid metabolic processGO:00327871520.012
aromatic compound catabolic processGO:00194391680.012
divalent metal ion transportGO:00708381320.012
fractalkine metabolic processGO:005075630.012
eye developmentGO:0001654500.012
regulation of signal transductionGO:00099663180.012
reactive oxygen species biosynthetic processGO:190340980.012
cell morphogenesis involved in differentiationGO:00009041190.012
renin secretion into blood streamGO:000200110.012
positive regulation of the force of heart contraction by epinephrineGO:000305910.012
anatomical structure homeostasisGO:0060249290.012
chemical homeostasisGO:00488782920.012
feeding behaviorGO:0007631530.012
positive regulation of saliva secretionGO:004687830.012
neural crest cell migrationGO:000175510.012
cytosolic calcium ion homeostasisGO:00514801400.012
response to purine containing compoundGO:00140741260.011
epithelial cell differentiationGO:0030855710.011
skeletal muscle organ developmentGO:0060538330.011
negative regulation of nucleic acid templated transcriptionGO:19035071170.011
purine ribonucleoside monophosphate catabolic processGO:0009169550.011
dephosphorylationGO:0016311980.011
regulation of monooxygenase activityGO:003276880.011
positive regulation of protein metabolic processGO:00512471780.011
response to lead ionGO:0010288330.011
progesterone biosynthetic processGO:000670130.011
regulation of oxidoreductase activityGO:0051341110.011
positive regulation of organelle organizationGO:0010638480.011
appendage morphogenesisGO:003510740.011
negative regulation of rna metabolic processGO:00512531230.011
taxisGO:0042330670.011
regulation of homotypic cell cell adhesionGO:003411040.011
positive regulation of phosphate metabolic processGO:00459372620.011
dopamine secretionGO:0014046150.011
endoplasmic reticulum organizationGO:000702910.011
metal ion transportGO:00300012890.011
oxidation reduction processGO:00551143040.011
regulation of muscle system processGO:0090257790.011
rho protein signal transductionGO:0007266110.011
response to histamineGO:003477630.011
response to glucocorticoidGO:00513842230.011
regulation of neuron differentiationGO:00456642080.011
molting cycleGO:004230330.011
regulation of cell morphogenesisGO:0022604770.011
immune responseGO:00069551040.011
regulation of transporter activityGO:0032409500.011
cellular response to acid chemicalGO:0071229750.011
regulation of cell migrationGO:00303341280.011
lipid localizationGO:0010876620.011
cellular response to metal ionGO:0071248550.011
negative regulation of biosynthetic processGO:00098901680.011
cell adhesionGO:00071551100.011
purine ribonucleotide metabolic processGO:00091502270.011
regulation of growthGO:00400081050.011
modified amino acid transportGO:0072337120.010
Rat
positive regulation of amine transportGO:0051954260.010
purine containing compound biosynthetic processGO:0072522850.010
cell morphogenesisGO:00009021420.010
tripeptide transportGO:004293920.010
Rat
embryonic pattern specificationGO:000988010.010
negative regulation of synaptic transmission gabaergicGO:003222960.010
protein oligomerizationGO:00512591910.010
Rat
steroid biosynthetic processGO:0006694480.010
synaptic transmission glutamatergicGO:0035249330.010
diterpenoid metabolic processGO:0016101330.010
organonitrogen compound catabolic processGO:19015651790.010
ion homeostasisGO:00508012120.010
regulation of ossificationGO:0030278320.010
spinal cord developmentGO:0021510270.010
ribonucleoside monophosphate metabolic processGO:0009161880.010
epithelial cell proliferationGO:0050673540.010
cellular response to glucocorticoid stimulusGO:0071385680.010
regulation of purine nucleotide metabolic processGO:19005421150.010
epithelium developmentGO:0060429960.010
learning or memoryGO:0007611900.010
muscle tissue developmentGO:0060537580.010
cell projection organizationGO:00300303020.010
negative regulation of neuron deathGO:1901215690.010
intracellular transportGO:00469071850.010
response to woundingGO:00096112540.010
cellular response to dexamethasone stimulusGO:0071549360.010

Slc22a2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.016
disease of metabolismDOID:001466700.016
endocrine system diseaseDOID:2800.012
disease of anatomical entityDOID:700.012