Rattus norvegicus

40 known processes

Slc22a8

solute carrier family 22 (organic anion transporter), member 8

(Aliases: Roct,MGC93369,OCT3,Oat3)

Slc22a8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
amino acid transportGO:0006865700.644
transmembrane transportGO:00550854120.413
anion transportGO:00068201780.353
homeostatic processGO:00425923310.215
organic acid transportGO:00158491160.214
nitrogen compound transportGO:00717052290.199
renal sodium excretionGO:0035812200.189
anion transmembrane transportGO:0098656770.161
Rat
regulation of cell proliferationGO:00421273590.159
carboxylic acid transportGO:00469421150.151
cellular response to oxygen containing compoundGO:19017013860.136
regenerationGO:00310991630.133
cellular chemical homeostasisGO:00550822470.130
divalent inorganic cation homeostasisGO:00725071650.123
fatty acid derivative metabolic processGO:1901568380.120
cation transmembrane transportGO:00986552630.119
metal ion homeostasisGO:00550651860.118
sulfur compound transportGO:007234880.116
monovalent inorganic cation transportGO:00156721720.114
regulation of blood pressureGO:0008217830.112
hormone transportGO:00099141210.110
Rat
positive regulation of developmental processGO:00510942830.108
neuron developmentGO:00486662860.105
response to decreased oxygen levelsGO:00362932370.104
protein oligomerizationGO:00512591910.102
Rat
cellular component assemblyGO:00226073600.101
Rat
regulation of anatomical structure sizeGO:00900661350.099
metal ion transportGO:00300012890.098
negative regulation of cell deathGO:00605482290.097
response to woundingGO:00096112540.095
multi multicellular organism processGO:00447061380.094
sodium ion transmembrane transportGO:0035725670.094
learningGO:0007612330.093
rhythmic processGO:00485111560.093
cellular homeostasisGO:00197252520.093
regulation of nervous system developmentGO:00519602640.093
organic acid metabolic processGO:00060822920.093
monocarboxylic acid transportGO:0015718520.092
Rat
sensory perceptionGO:00076001010.092
macromolecular complex assemblyGO:00650032730.091
Rat
carboxylic acid metabolic processGO:00197522890.090
regulation of hormone levelsGO:00108171870.089
Rat
central nervous system developmentGO:00074173110.088
reproductive processGO:00224143720.085
regulation of multicellular organismal developmentGO:20000263760.081
dicarboxylic acid transportGO:0006835340.080
response to inorganic substanceGO:00100353770.080
response to oxidative stressGO:00069791860.079
response to campGO:0051591910.076
neurological system processGO:00508772190.076
regulation of neuron differentiationGO:00456642080.075
regulation of cell differentiationGO:00455953200.075
unsaturated fatty acid metabolic processGO:0033559390.073
response to oxygen levelsGO:00704822650.072
response to hypoxiaGO:00016662310.072
amino acid transmembrane transportGO:0003333330.072
Rat
ion homeostasisGO:00508012120.072
ion transmembrane transportGO:00342203650.071
cellular cation homeostasisGO:00300031800.071
agingGO:00075682410.070
positive regulation of cell communicationGO:00106472710.070
cation transportGO:00068123820.070
cellular ion homeostasisGO:00068731840.065
organic anion transportGO:00157111320.065
regulation of amino acid transportGO:0051955250.063
positive regulation of cell differentiationGO:00455972170.063
locomotionGO:00400112370.062
organelle organizationGO:00069962660.062
cation homeostasisGO:00550801950.062
chemical homeostasisGO:00488782920.062
response to toxic substanceGO:00096361330.061
negative regulation of programmed cell deathGO:00430691830.061
regulation of secretionGO:00510462240.061
sensory organ developmentGO:0007423740.060
acid secretionGO:0046717480.060
response to corticosteroidGO:00319602350.059
response to estrogenGO:00436272320.058
regulation of behaviorGO:0050795610.057
positive regulation of transportGO:00510502450.057
negative regulation of cellular metabolic processGO:00313242810.056
cellular calcium ion homeostasisGO:00068741600.056
amide transportGO:00428861050.056
cellular divalent inorganic cation homeostasisGO:00725031620.056
g protein coupled receptor signaling pathwayGO:00071862420.055
regulation of blood vessel sizeGO:0050880890.053
protein complex biogenesisGO:00702712630.053
Rat
circulatory system processGO:00030131830.053
neuron differentiationGO:00301823680.052
response to insulinGO:00328681330.051
response to acid chemicalGO:00011012220.051
sodium ion transportGO:0006814820.051
multi organism reproductive processGO:00447032620.051
regulation of locomotionGO:00400121480.050
regulation of peptide transportGO:0090087870.050
regulation of organic acid transportGO:0032890350.050
organic hydroxy compound metabolic processGO:19016151150.050
positive regulation of nervous system developmentGO:00519621780.049
wound healingGO:00420601220.048
gliogenesisGO:0042063930.048
regulation of tube sizeGO:0035150890.048
peptide secretionGO:0002790860.047
negative regulation of ion transportGO:0043271510.047
cellular response to lipidGO:00713962010.046
positive regulation of signalingGO:00230562700.045
multicellular organismal reproductive processGO:00486092330.045
regulation of neurogenesisGO:00507672470.045
regulation of anion transportGO:0044070430.045
regulation of body fluid levelsGO:0050878900.045
protein complex subunit organizationGO:00718223020.045
Rat
modified amino acid transportGO:0072337120.045
organic hydroxy compound transportGO:0015850770.045
Rat
regulation of cell developmentGO:00602842630.044
vascular process in circulatory systemGO:0003018960.044
positive regulation of nucleobase containing compound metabolic processGO:00459353190.042
positive regulation of response to stimulusGO:00485842850.042
multicellular organism reproductionGO:00325042330.042
cell projection organizationGO:00300303020.041
action potentialGO:0001508540.041
negative regulation of nervous system developmentGO:0051961790.041
positive regulation of neurogenesisGO:00507691650.041
single organism biosynthetic processGO:00447113420.041
response to radiationGO:00093141370.041
alcohol metabolic processGO:0006066770.041
fatty acid biosynthetic processGO:0006633330.040
cell cell signalingGO:00072673350.040
steroid metabolic processGO:0008202730.040
muscle cell proliferationGO:0033002840.040
head developmentGO:00603222470.040
amine metabolic processGO:0009308380.039
peptide transportGO:0015833970.039
response to ketoneGO:19016541820.039
negative regulation of developmental processGO:00510931250.039
cellular component biogenesisGO:00440853680.039
Rat
response to organophosphorusGO:00466831020.038
response to nutrient levelsGO:00316673700.038
carboxylic acid biosynthetic processGO:0046394830.038
response to glucoseGO:00097491360.038
behaviorGO:00076102050.038
protein complex assemblyGO:00064612630.038
Rat
response to monosaccharideGO:00342841590.038
response to purine containing compoundGO:00140741260.038
hepaticobiliary system developmentGO:0061008900.038
response to ionizing radiationGO:0010212590.038
negative regulation of transportGO:00510511360.037
cellular amine metabolic processGO:0044106380.037
oxoacid metabolic processGO:00434362900.037
fatty acid metabolic processGO:0006631990.037
negative regulation of nucleobase containing compound metabolic processGO:00459341530.036
anatomical structure morphogenesisGO:00096532980.036
positive regulation of gamma aminobutyric acid secretionGO:001405440.036
cellular response to endogenous stimulusGO:00714953770.035
regulation of apoptotic processGO:00429813350.035
cognitionGO:0050890920.035
negative regulation of neuron differentiationGO:0045665620.035
positive regulation of peptide secretionGO:0002793520.035
circadian rhythmGO:0007623880.034
cellular response to organic cyclic compoundGO:00714072020.034
secretionGO:00469033070.034
macromolecular complex subunit organizationGO:00439333390.034
Rat
regulation of anatomical structure morphogenesisGO:00226031410.034
negative regulation of metabolic processGO:00098923310.034
regulation of homeostatic processGO:00328441010.033
apoptotic processGO:00069153810.033
organic acid biosynthetic processGO:0016053830.033
brain developmentGO:00074202470.033
response to extracellular stimulusGO:00099913800.033
synaptic transmissionGO:00072682350.033
positive regulation of secretionGO:00510471400.033
blood circulationGO:00080151830.032
cytosolic calcium ion homeostasisGO:00514801400.032
pyridine nucleotide biosynthetic processGO:001936320.032
macromolecule localizationGO:00330362520.032
regulation of hormone secretionGO:00468831060.032
single organism behaviorGO:00447081300.031
regulation of secretion by cellGO:19035302080.031
localization of cellGO:00516742020.031
response to transition metal nanoparticleGO:19902671220.031
sensory perception of painGO:0019233730.031
positive regulation of cell proliferationGO:00082842490.031
regulation of peptide hormone secretionGO:0090276800.031
anatomical structure formation involved in morphogenesisGO:0048646830.031
regulation of neural precursor cell proliferationGO:2000177160.031
lipid biosynthetic processGO:00086101280.031
regulation of inflammatory responseGO:0050727480.030
learning or memoryGO:0007611900.030
positive regulation of phosphorus metabolic processGO:00105622620.030
signal transduction by phosphorylationGO:00230141440.030
cellular response to alcoholGO:0097306870.030
cellular response to hormone stimulusGO:00328702470.029
organophosphate biosynthetic processGO:00904071430.029
hormone secretionGO:00468791150.029
reproductive system developmentGO:00614581280.028
regulation of rna metabolic processGO:00512523910.028
cell migrationGO:00164771970.028
negative regulation of gene expressionGO:00106291990.028
cellular metal ion homeostasisGO:00068751720.028
cellular response to stressGO:00335542690.028
programmed cell deathGO:00125013920.027
regulation of vascular permeabilityGO:0043114100.027
positive regulation of multicellular organismal processGO:00512403870.027
cell motilityGO:00488702020.027
regulation of cell projection organizationGO:00313441750.027
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.027
regulation of ion transportGO:00432692450.027
regulation of feeding behaviorGO:0060259140.027
icosanoid metabolic processGO:0006690380.027
embryonic skeletal system developmentGO:004870630.026
inner ear receptor cell differentiationGO:006011320.026
single organism organelle organizationGO:19025891800.026
regulation of excretionGO:0044062210.026
response to estradiolGO:00323551640.026
regulation of signal transductionGO:00099663180.026
excretionGO:0007588240.026
positive regulation of cellular biosynthetic processGO:00313282950.026
cellular component movementGO:00069282480.025
organonitrogen compound biosynthetic processGO:19015661670.025
mechanoreceptor differentiationGO:004249020.025
regulation of renal sodium excretionGO:0035813200.025
regulation of smooth muscle cell proliferationGO:0048660750.025
regulation of membrane potentialGO:00423911100.025
potassium ion transportGO:0006813970.025
response to mechanical stimulusGO:00096121340.025
positive regulation of biosynthetic processGO:00098913190.024
response to peptide hormoneGO:00434342780.024
negative regulation of apoptotic processGO:00430661810.024
regulation of protein metabolic processGO:00512462890.024
peptide hormone secretionGO:0030072840.024
dna metabolic processGO:0006259960.024
memoryGO:0007613540.024
female pregnancyGO:00075651220.024
regulation of response to external stimulusGO:00321011060.024
negative regulation of cell communicationGO:00106481580.023
transcription from rna polymerase ii promoterGO:00063662520.023
positive regulation of nucleic acid templated transcriptionGO:19035081970.023
response to peptideGO:19016522920.023
regulation of response to stressGO:00801341260.023
sodium ion homeostasisGO:0055078230.023
lipid metabolic processGO:00066292830.023
regulation of peptide secretionGO:0002791820.023
pyridine containing compound metabolic processGO:0072524320.023
lipid localizationGO:0010876620.022
negative regulation of cell developmentGO:0010721820.022
response to glucocorticoidGO:00513842230.022
regulation of cellular component organizationGO:00511283680.022
positive regulation of cell developmentGO:00107201760.021
mapk cascadeGO:00001651400.021
regulation of sensory perceptionGO:0051931290.021
renal system developmentGO:0072001670.021
response to vitamin dGO:0033280340.021
regulation of cellular localizationGO:00603412630.021
negative regulation of hormone secretionGO:0046888460.021
positive regulation of cellular protein metabolic processGO:00322701670.021
cellular ketone metabolic processGO:0042180510.021
positive regulation of synaptic transmissionGO:0050806620.021
positive regulation of cellular component organizationGO:00511302000.021
isoprenoid metabolic processGO:0006720450.021
negative regulation of transcription dna templatedGO:00458921160.021
response to vitaminGO:00332731310.021
regulation of synaptic transmission gabaergicGO:0032228170.020
negative regulation of multicellular organismal processGO:00512412030.020
positive regulation of macromolecule biosynthetic processGO:00105572470.020
regulation of acute inflammatory responseGO:0002673230.020
positive regulation of phosphate metabolic processGO:00459372620.020
negative regulation of secretion by cellGO:1903531720.020
heart processGO:0003015570.020
response to reactive oxygen speciesGO:00003021200.020
positive regulation of phosphorylationGO:00423271770.020
positive regulation of peptide hormone secretionGO:0090277500.020
nicotinamide nucleotide biosynthetic processGO:001935920.020
smooth muscle cell proliferationGO:0048659770.019
positive regulation of gene expressionGO:00106282440.019
positive regulation of cytosolic calcium ion concentrationGO:00072041220.019
amine transportGO:0015837570.019
response to hexoseGO:00097461440.019
hair cell differentiationGO:003531520.019
signal releaseGO:00230611450.019
negative regulation of secretionGO:0051048820.019
positive regulation of nitrogen compound metabolic processGO:00511733340.019
cell type specific apoptotic processGO:00972851340.019
positive regulation of neuron differentiationGO:00456661260.019
positive regulation of blood circulationGO:1903524650.019
regulation of system processGO:00440572080.019
regulation of neuron deathGO:19012141150.019
adult locomotory behaviorGO:000834440.019
negative regulation of neurogenesisGO:0050768780.018
growthGO:00400071650.018
cellular response to abiotic stimulusGO:0071214850.018
regulation of protein modification processGO:00313991940.018
oligopeptide transportGO:000685740.018
negative regulation of cell proliferationGO:00082851190.018
regulation of molecular functionGO:00650093980.018
positive regulation of protein metabolic processGO:00512471780.018
negative regulation of synaptic transmission dopaminergicGO:003222740.018
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
cellular response to peptide hormone stimulusGO:00713751200.018
angiotensin mediated drinking behaviorGO:000305120.018
regulation of response to woundingGO:1903034690.018
regulation of neurological system processGO:0031644430.018
single organism reproductive processGO:00447022970.017
regulation of cellular amine metabolic processGO:003323880.017
locomotor rhythmGO:004547510.017
ovulation cycle processGO:0022602500.017
intracellular signal transductionGO:00355563140.017
monocarboxylic acid metabolic processGO:00327871520.017
neurotransmitter uptakeGO:000150430.017
reproductive structure developmentGO:00486081280.017
multicellular organismal response to stressGO:0033555250.017
rna metabolic processGO:00160704060.017
cellular hormone metabolic processGO:0034754490.017
epithelial cell proliferationGO:0050673540.017
sexual reproductionGO:00199531480.017
regulation of phosphorus metabolic processGO:00511743490.016
regulation of programmed cell deathGO:00430673410.016
positive regulation of long term synaptic potentiationGO:190027340.016
glutamate secretionGO:0014047190.016
developmental process involved in reproductionGO:00030061590.016
brain renin angiotensin systemGO:000203530.016
regulation of glutamate secretionGO:0014048170.016
negative regulation of amine transportGO:0051953240.016
negative regulation of cell differentiationGO:0045596990.016
urogenital system developmentGO:0001655780.016
response to osmotic stressGO:0006970420.016
response to cgmpGO:007030530.016
neuron neuron synaptic transmissionGO:0007270600.016
negative regulation of nitrogen compound metabolic processGO:00511721610.015
regulation of neuron projection developmentGO:00109751610.015
sperm ejaculationGO:004271350.015
glucose homeostasisGO:0042593750.015
calcium ion homeostasisGO:00550741620.015
regulation of phosphorylationGO:00423252480.015
gamma aminobutyric acid transportGO:001581280.015
secretion by cellGO:00329402480.015
anterior posterior pattern specificationGO:000995210.015
inorganic anion transportGO:0015698410.015
blood vessel developmentGO:0001568690.015
positive regulation of protein phosphorylationGO:00019341350.015
positive regulation of intracellular signal transductionGO:19025331380.015
positive regulation of protein modification processGO:00314011420.015
vasoconstrictionGO:0042310540.015
nicotine metabolic processGO:001893310.015
negative regulation of glutamate secretionGO:001405090.014
synaptic transmission gabaergicGO:0051932220.014
protein heterooligomerizationGO:0051291890.014
generation of ovulation cycle rhythmGO:006011220.014
hyperosmotic responseGO:0006972180.014
protein phosphorylationGO:00064683450.014
icosanoid biosynthetic processGO:0046456180.014
regulation of transcription dna templatedGO:00063553740.014
response to sulfur dioxideGO:001047730.014
response to testosteroneGO:0033574550.014
response to carbohydrateGO:00097431830.014
cellular glucose homeostasisGO:0001678660.014
positive regulation of cell projection organizationGO:00313461110.014
regulation of sensory perception of painGO:0051930290.014
positive regulation of cellular component movementGO:00512721020.014
transmission of nerve impulseGO:0019226420.014
cellular response to external stimulusGO:00714961180.014
angiogenesisGO:0001525530.014
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.014
regulation of cell growthGO:0001558850.013
regulation of rna biosynthetic processGO:20011413810.013
regulation of phosphate metabolic processGO:00192203490.013
negative regulation of macromolecule biosynthetic processGO:00105581480.013
chemosensory behaviorGO:000763520.013
gonad developmentGO:00084061040.013
inorganic cation transmembrane transportGO:00986622020.013
positive regulation of signal transductionGO:00099671750.013
alpha amino acid metabolic processGO:1901605710.013
small molecule biosynthetic processGO:00442831240.013
regulation of amine transportGO:0051952540.013
cofactor metabolic processGO:0051186950.013
cellular modified amino acid metabolic processGO:0006575610.013
diterpenoid metabolic processGO:0016101330.013
negative regulation of macromolecule metabolic processGO:00106052600.013
vitamin transportGO:0051180140.013
cellular response to glucose stimulusGO:0071333650.013
regulation of cellular protein metabolic processGO:00322682670.013
inorganic ion transmembrane transportGO:00986602290.013
gamma aminobutyric acid secretionGO:001405160.013
neuron projection developmentGO:00311752730.013
gland developmentGO:00487321550.012
regulation of synaptic transmission glutamatergicGO:0051966260.012
micturitionGO:006007340.012
antibiotic transportGO:004289120.012
Rat
peristalsisGO:003043220.012
regulation of insulin secretionGO:0050796650.012
reproductionGO:00000032450.012
positive regulation of cell motilityGO:2000147970.012
nicotinamide nucleotide metabolic processGO:0046496280.012
regulation of ion homeostasisGO:2000021630.012
trichloroethylene metabolic processGO:001897910.012
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.012
response to activityGO:0014823730.012
glial cell differentiationGO:0010001650.012
germ cell migrationGO:000835410.012
sex differentiationGO:00075481130.012
response to metal ionGO:00100382530.012
vasodilationGO:0042311440.012
regulation of synaptic transmissionGO:00508041410.012
hematopoietic progenitor cell differentiationGO:000224420.012
positive regulation of hormone secretionGO:0046887650.012
regulation of blood circulationGO:19035221100.012
secretion by tissueGO:0032941370.012
cellular amino acid metabolic processGO:00065201070.012
neuron deathGO:00709971270.012
synaptic transmission cholinergicGO:0007271110.012
lipid transportGO:0006869610.012
negative regulation of response to stimulusGO:00485851550.012
regulation of cellular ketone metabolic processGO:0010565270.012
ovulation cycleGO:0042698670.012
cellular response to organonitrogen compoundGO:00714171970.012
carbohydrate homeostasisGO:0033500750.012
tongue morphogenesisGO:004358730.012
regulation of cellular component biogenesisGO:0044087860.012
nucleoside phosphate metabolic processGO:00067532830.012
mesoderm developmentGO:000749820.012
glandular epithelial cell differentiationGO:000206740.012
response to progesteroneGO:0032570480.011
development of primary sexual characteristicsGO:00451371070.011
response to nutrientGO:00075842480.011
positive regulation of vascular permeabilityGO:004311770.011
response to lipopolysaccharideGO:00324961910.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
neuronal action potentialGO:0019228350.011
response to nicotineGO:0035094510.011
negative regulation of cellular protein metabolic processGO:00322691060.011
divalent inorganic cation transportGO:00725111340.011
positive regulation of organic acid transportGO:0032892220.011
regulation of leukocyte migrationGO:0002685240.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.011
organophosphate metabolic processGO:00196373700.011
ossificationGO:0001503700.011
defecationGO:003042110.011
terpenoid metabolic processGO:0006721370.011
regulation of dna metabolic processGO:0051052600.011
regulation of protein localizationGO:0032880810.011
body fluid secretionGO:0007589410.011
enzyme linked receptor protein signaling pathwayGO:00071671160.011
positive regulation of cytoskeleton organizationGO:0051495260.011
negative regulation of blood pressureGO:0045776290.011
regulation of metal ion transportGO:00109591180.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
protein homooligomerizationGO:0051260910.011
Rat
multicellular organismal macromolecule metabolic processGO:0044259210.011
response to painGO:0048265110.011
negative regulation of cytosolic calcium ion concentrationGO:0051481100.011
organic hydroxy compound biosynthetic processGO:1901617510.011
negative regulation of synaptic transmissionGO:0050805290.011
regulation of organ formationGO:000315620.010
monocarboxylic acid biosynthetic processGO:0072330480.010
regulation of epithelial cell proliferationGO:0050678490.010
organ regenerationGO:00311001010.010
cell morphogenesisGO:00009021420.010
cellular biogenic amine metabolic processGO:0006576300.010
intestinal absorptionGO:005089230.010
positive regulation of organelle organizationGO:0010638480.010
rho protein signal transductionGO:0007266110.010
regulation of mapk cascadeGO:00434081160.010
positive regulation of homeostatic processGO:0032846490.010
regulation of catalytic activityGO:00507903040.010
regulation of cellular amino acid metabolic processGO:000652120.010
negative regulation of synaptic transmission gabaergicGO:003222960.010

Slc22a8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.118
nervous system diseaseDOID:86300.118
sensory system diseaseDOID:005015500.091
eye and adnexa diseaseDOID:149200.091
eye diseaseDOID:561400.091
disease of metabolismDOID:001466700.030
retinal diseaseDOID:567900.027
retinal degenerationDOID:846600.022
retinitis pigmentosaDOID:1058400.021
disease of cellular proliferationDOID:1456600.016
central nervous system diseaseDOID:33100.013
urinary system diseaseDOID:1800.012
kidney diseaseDOID:55700.012
connective tissue diseaseDOID:6500.012
musculoskeletal system diseaseDOID:1700.012