Rattus norvegicus

29 known processes

Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

Akr1b10 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of nitrogen compound metabolic processGO:00511733340.146
nucleic acid templated transcriptionGO:00976593790.131
rna biosynthetic processGO:00327743800.115
transcription from rna polymerase ii promoterGO:00063662520.112
positive regulation of cellular biosynthetic processGO:00313282950.100
regulation of rna biosynthetic processGO:20011413810.095
regulation of cellular component organizationGO:00511283680.082
regulation of transcription dna templatedGO:00063553740.082
rna metabolic processGO:00160704060.080
positive regulation of nucleobase containing compound metabolic processGO:00459353190.080
cellular response to endogenous stimulusGO:00714953770.078
Rat
transcription dna templatedGO:00063513770.075
regulation of rna metabolic processGO:00512523910.073
regulation of phosphorus metabolic processGO:00511743490.070
regulation of nucleic acid templated transcriptionGO:19035063800.069
regulation of signal transductionGO:00099663180.068
Rat
negative regulation of metabolic processGO:00098923310.066
regulation of molecular functionGO:00650093980.062
regulation of transcription from rna polymerase ii promoterGO:00063572340.061
positive regulation of gene expressionGO:00106282440.061
positive regulation of transcription dna templatedGO:00458931970.059
protein phosphorylationGO:00064683450.058
nucleobase containing small molecule metabolic processGO:00550863160.056
cellular response to hormone stimulusGO:00328702470.056
regulation of phosphorylationGO:00423252480.056
nucleoside phosphate metabolic processGO:00067532830.055
positive regulation of phosphate metabolic processGO:00459372620.055
cellular component assemblyGO:00226073600.053
positive regulation of macromolecule biosynthetic processGO:00105572470.053
regulation of phosphate metabolic processGO:00192203490.051
positive regulation of transportGO:00510502450.051
intracellular signal transductionGO:00355563140.051
Rat
response to nutrientGO:00075842480.051
negative regulation of macromolecule metabolic processGO:00106052600.050
regulation of intracellular signal transductionGO:19025312180.050
Rat
positive regulation of rna biosynthetic processGO:19026801970.049
positive regulation of phosphorus metabolic processGO:00105622620.049
positive regulation of rna metabolic processGO:00512542030.049
regulation of protein metabolic processGO:00512462890.048
positive regulation of cellular component organizationGO:00511302000.048
positive regulation of nucleic acid templated transcriptionGO:19035081970.047
cellular response to nitrogen compoundGO:19016992100.046
Rat
positive regulation of cell communicationGO:00106472710.045
Rat
negative regulation of cellular metabolic processGO:00313242810.045
ribose phosphate metabolic processGO:00196932350.045
response to nutrient levelsGO:00316673700.044
negative regulation of signalingGO:00230571570.043
regulation of cellular localizationGO:00603412630.041
regulation of programmed cell deathGO:00430673410.041
negative regulation of gene expressionGO:00106291990.040
positive regulation of molecular functionGO:00440932300.040
regulation of cell differentiationGO:00455953200.039
purine containing compound metabolic processGO:00725212530.038
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.037
regulation of catalytic activityGO:00507903040.037
response to extracellular stimulusGO:00099913800.036
carbohydrate derivative metabolic processGO:19011353460.036
Human
programmed cell deathGO:00125013920.036
regulation of cellular ketone metabolic processGO:0010565270.036
reproductionGO:00000032450.036
Rat
regulation of cell projection organizationGO:00313441750.035
positive regulation of catalytic activityGO:00430851840.035
regulation of neurogenesisGO:00507672470.035
amine metabolic processGO:0009308380.035
nucleotide metabolic processGO:00091172790.034
multicellular organismal reproductive processGO:00486092330.034
Rat
positive regulation of response to stimulusGO:00485842850.034
Rat
regulation of secretion by cellGO:19035302080.033
positive regulation of protein metabolic processGO:00512471780.033
positive regulation of signalingGO:00230562700.032
Rat
positive regulation of phosphorylationGO:00423271770.031
negative regulation of biosynthetic processGO:00098901680.031
central nervous system developmentGO:00074173110.031
Rat Fly
regulation of cellular amine metabolic processGO:003323880.031
protein complex subunit organizationGO:00718223020.030
purine ribonucleotide metabolic processGO:00091502270.030
neuron differentiationGO:00301823680.030
cellular amino acid metabolic processGO:00065201070.030
negative regulation of cell deathGO:00605482290.029
heterocycle catabolic processGO:00467001670.029
regulation of cellular protein metabolic processGO:00322682670.029
regulation of multicellular organismal developmentGO:20000263760.028
ion transmembrane transportGO:00342203650.028
small gtpase mediated signal transductionGO:0007264360.028
cellular catabolic processGO:00442482950.028
Human
positive regulation of multicellular organismal processGO:00512403870.028
cellular component biogenesisGO:00440853680.028
positive regulation of developmental processGO:00510942830.027
negative regulation of nitrogen compound metabolic processGO:00511721610.027
positive regulation of biosynthetic processGO:00098913190.027
positive regulation of signal transductionGO:00099671750.027
Rat
secretionGO:00469033070.027
signal releaseGO:00230611450.027
cell cell signalingGO:00072673350.027
cellular ketone metabolic processGO:0042180510.027
Human
regulation of cell proliferationGO:00421273590.027
Rat
cell projection organizationGO:00300303020.026
organophosphate metabolic processGO:00196373700.026
cellular chemical homeostasisGO:00550822470.026
biological adhesionGO:00226101100.025
cellular amine metabolic processGO:0044106380.025
organophosphate biosynthetic processGO:00904071430.025
regulation of hormone levelsGO:00108171870.025
regulation of cellular amino acid metabolic processGO:000652120.025
negative regulation of cellular biosynthetic processGO:00313271610.025
protein complex assemblyGO:00064612630.025
negative regulation of programmed cell deathGO:00430691830.025
secretion by cellGO:00329402480.025
purine nucleotide metabolic processGO:00061632290.025
sensory perception of painGO:0019233730.024
catabolic processGO:00090563510.024
Human
g protein coupled receptor signaling pathwayGO:00071862420.024
signal transduction by phosphorylationGO:00230141440.024
defense responseGO:00069521940.024
locomotionGO:00400112370.024
oxidation reduction processGO:00551143040.024
organic acid metabolic processGO:00060822920.024
cellular response to oxygen containing compoundGO:19017013860.024
Rat
establishment of tissue polarityGO:000716420.024
response to glucocorticoidGO:00513842230.024
macromolecular complex subunit organizationGO:00439333390.024
regulation of cell developmentGO:00602842630.023
positive regulation of neurogenesisGO:00507691650.023
negative regulation of cell communicationGO:00106481580.023
cell motilityGO:00488702020.023
negative regulation of apoptotic processGO:00430661810.023
apoptotic processGO:00069153810.023
response to alkaloidGO:00432791320.023
single organism catabolic processGO:00447122830.023
Human
positive regulation of cell developmentGO:00107201760.023
neuron projection developmentGO:00311752730.022
multicellular organism reproductionGO:00325042330.022
Rat
positive regulation of cytosolic calcium ion concentrationGO:00072041220.022
response to ketoneGO:19016541820.022
Rat
regulation of protein phosphorylationGO:00019321830.022
regulation of membrane potentialGO:00423911100.022
regulation of catabolic processGO:00098941130.022
response to carbohydrateGO:00097431830.022
negative regulation of macromolecule biosynthetic processGO:00105581480.022
dendrite developmentGO:0016358720.022
positive regulation of cell differentiationGO:00455972170.022
neuron apoptotic processGO:0051402880.022
negative regulation of nucleobase containing compound metabolic processGO:00459341530.021
ribonucleotide metabolic processGO:00092592310.021
purine containing compound catabolic processGO:00725231380.021
negative regulation of response to stimulusGO:00485851550.021
positive regulation of cellular protein metabolic processGO:00322701670.021
chromosome segregationGO:000705920.021
aromatic compound catabolic processGO:00194391680.021
proteolysisGO:00065081750.021
regulation of system processGO:00440572080.021
cellular response to peptideGO:19016531330.021
Rat
synaptic transmissionGO:00072682350.021
carboxylic acid metabolic processGO:00197522890.021
regulation of apoptotic processGO:00429813350.021
circulatory system processGO:00030131830.020
response to corticosteroidGO:00319602350.020
glycosyl compound metabolic processGO:19016571820.020
Human
purine nucleoside triphosphate metabolic processGO:00091441410.020
purine ribonucleoside metabolic processGO:00461281680.020
negative regulation of cell developmentGO:0010721820.020
ribonucleoside metabolic processGO:00091191740.020
cellular component movementGO:00069282480.020
cellular response to stressGO:00335542690.020
Rat
oxoacid metabolic processGO:00434362900.019
negative regulation of transportGO:00510511360.019
cation transmembrane transportGO:00986552630.019
mapk cascadeGO:00001651400.019
negative regulation of rna biosynthetic processGO:19026791180.019
metal ion homeostasisGO:00550651860.019
positive regulation of hydrolase activityGO:0051345860.019
positive regulation of cellular amine metabolic processGO:003324030.019
regulation of neuron deathGO:19012141150.019
positive regulation of nervous system developmentGO:00519621780.018
regulation of transferase activityGO:00513381230.018
response to growth factorGO:00708481890.018
regulation of response to stressGO:00801341260.018
reproductive processGO:00224143720.018
Rat
negative regulation of multicellular organismal processGO:00512412030.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
divalent inorganic cation transportGO:00725111340.018
negative regulation of phosphorus metabolic processGO:0010563800.018
macromolecule localizationGO:00330362520.018
regulation of hydrolase activityGO:00513361430.018
regulation of neuron differentiationGO:00456642080.018
negative regulation of signal transductionGO:0009968830.018
regulation of neuron apoptotic processGO:0043523830.018
protein complex biogenesisGO:00702712630.017
regulation of mapk cascadeGO:00434081160.017
metal ion transportGO:00300012890.017
stress activated protein kinase signaling cascadeGO:0031098370.017
Rat
positive regulation of protein phosphorylationGO:00019341350.017
organic substance catabolic processGO:19015753160.017
Human
response to oxygen levelsGO:00704822650.017
divalent inorganic cation homeostasisGO:00725071650.017
cellular response to organic cyclic compoundGO:00714072020.017
single organism biosynthetic processGO:00447113420.017
Rat
ras protein signal transductionGO:0007265290.017
action potentialGO:0001508540.017
brain developmentGO:00074202470.017
Rat Fly
negative regulation of nucleic acid templated transcriptionGO:19035071170.017
regulation of nervous system developmentGO:00519602640.017
response to lipopolysaccharideGO:00324961910.017
head developmentGO:00603222470.017
Rat Fly
positive regulation of intracellular signal transductionGO:19025331380.017
Rat
negative regulation of rna metabolic processGO:00512531230.017
regulation of secretionGO:00510462240.017
peptidyl amino acid modificationGO:00181931260.017
sensory perceptionGO:00076001010.017
neuromuscular processGO:005090520.017
regulation of neuron projection developmentGO:00109751610.017
cation transportGO:00068123820.016
nucleobase containing compound catabolic processGO:00346551520.016
transmembrane transportGO:00550854120.016
bmp signaling pathwayGO:003050940.016
response to acid chemicalGO:00011012220.016
Rat
negative regulation of neuron deathGO:1901215690.016
regulation of anatomical structure sizeGO:00900661350.016
regulation of nucleotide metabolic processGO:00061401170.016
negative regulation of secretionGO:0051048820.016
nucleoside catabolic processGO:00091641260.016
neuron neuron synaptic transmissionGO:0007270600.016
response to ethanolGO:00454711620.016
axis specificationGO:000979840.016
response to molecule of bacterial originGO:00022371940.015
positive regulation of protein modification processGO:00314011420.015
regulation of protein modification processGO:00313991940.015
carbohydrate derivative biosynthetic processGO:19011371240.015
protein localizationGO:00081041910.015
blood circulationGO:00080151830.015
cytosolic calcium ion homeostasisGO:00514801400.015
response to decreased oxygen levelsGO:00362932370.015
response to hexoseGO:00097461440.015
hormone transportGO:00099141210.015
ion homeostasisGO:00508012120.015
regulation of proteasomal protein catabolic processGO:006113640.015
muscle system processGO:00030121150.015
negative regulation of molecular functionGO:00440921330.015
cellular cation homeostasisGO:00300031800.015
amine transportGO:0015837570.015
cellular calcium ion homeostasisGO:00068741600.015
non canonical wnt signaling pathwayGO:003556730.015
ribose phosphate biosynthetic processGO:0046390870.015
regulation of smooth muscle cell proliferationGO:0048660750.015
Rat
regulation of kinase activityGO:00435491170.015
tube developmentGO:0035295890.015
Rat
macromolecular complex assemblyGO:00650032730.015
cell type specific apoptotic processGO:00972851340.015
positive regulation of neuron projection developmentGO:0010976990.015
cell adhesionGO:00071551100.015
behaviorGO:00076102050.015
organ regenerationGO:00311001010.015
regulation of establishment of planar polarityGO:009017520.015
positive regulation of purine nucleotide metabolic processGO:1900544910.014
positive regulation of cell deathGO:00109421840.014
calcium ion homeostasisGO:00550741620.014
cellular homeostasisGO:00197252520.014
spermatogenesisGO:0007283990.014
neuron developmentGO:00486662860.014
nucleoside metabolic processGO:00091161790.014
adult locomotory behaviorGO:000834440.014
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.014
purine nucleoside metabolic processGO:00422781690.014
organophosphate catabolic processGO:00464341480.014
membrane organizationGO:0061024940.014
wnt signaling pathway planar cell polarity pathwayGO:006007120.014
cellular nitrogen compound catabolic processGO:00442701630.014
cellular response to growth factor stimulusGO:00713631620.014
nitrogen compound transportGO:00717052290.014
positive regulation of neuron differentiationGO:00456661260.014
response to estradiolGO:00323551640.014
response to monosaccharideGO:00342841590.014
purine nucleotide catabolic processGO:00061951360.014
response to glucoseGO:00097491360.014
growthGO:00400071650.014
negative regulation of cellular protein metabolic processGO:00322691060.014
regulation of vesicle mediated transportGO:0060627810.014
circulatory system developmentGO:00723591340.014
positive regulation of cell proliferationGO:00082842490.013
Rat
amide transportGO:00428861050.013
response to woundingGO:00096112540.013
sequestering of metal ionGO:005123890.013
dephosphorylationGO:0016311980.013
chemical homeostasisGO:00488782920.013
negative regulation of developmental processGO:00510931250.013
cytoplasmic transportGO:00164821150.013
intracellular transportGO:00469071850.013
glial cell differentiationGO:0010001650.013
cellular response to steroid hormone stimulusGO:0071383930.013
rhythmic processGO:00485111560.013
response to biotic stimulusGO:00096072260.013
sequestering of calcium ionGO:005120880.013
nucleoside phosphate catabolic processGO:19012921400.013
regulation of protein kinase activityGO:00458591050.013
single organism reproductive processGO:00447022970.013
Rat
single organism carbohydrate metabolic processGO:00447231180.013
Rat
hormone secretionGO:00468791150.013
negative regulation of secretion by cellGO:1903531720.013
regulation of ion transportGO:00432692450.013
cation homeostasisGO:00550801950.012
response to purine containing compoundGO:00140741260.012
calcium ion transportGO:00068161310.012
negative regulation of protein metabolic processGO:00512481140.012
regulation of response to external stimulusGO:00321011060.012
male gamete generationGO:0048232990.012
morphogenesis of a polarized epitheliumGO:000173810.012
embryonic pattern specificationGO:000988010.012
regulation of purine nucleotide metabolic processGO:19005421150.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
cell cycle checkpointGO:000007520.012
ribonucleoside catabolic processGO:00424541260.012
regulation of cellular component biogenesisGO:0044087860.012
regulation of cytoskeleton organizationGO:0051493490.012
establishment of planar polarityGO:000173610.012
response to other organismGO:00517072200.012
carbohydrate derivative catabolic processGO:19011361470.012
peptide transportGO:0015833970.012
neuron deathGO:00709971270.012
regulation of stem cell differentiationGO:200073620.012
nucleotide catabolic processGO:00091661390.012
negative regulation of amine transportGO:0051953240.012
response to bacteriumGO:00096172000.012
regulation of blood pressureGO:0008217830.012
regulation of dendrite developmentGO:0050773590.012
positive regulation of gtpase activityGO:0043547470.012
cell part morphogenesisGO:00329901230.012
negative regulation of catalytic activityGO:00430861030.011
regulation of cellular catabolic processGO:00313291010.011
camp metabolic processGO:0046058630.011
cardiovascular system developmentGO:00723581340.011
sulfur compound metabolic processGO:0006790700.011
multi organism reproductive processGO:00447032620.011
Rat
organic cyclic compound catabolic processGO:19013611750.011
response to external biotic stimulusGO:00432072210.011
negative regulation of neuron apoptotic processGO:0043524450.011
organonitrogen compound biosynthetic processGO:19015661670.011
gliogenesisGO:0042063930.011
embryonic axis specificationGO:000057810.011
organonitrogen compound catabolic processGO:19015651790.011
cytoskeleton organizationGO:00070101110.011
negative regulation of cell differentiationGO:0045596990.011
purine nucleoside triphosphate catabolic processGO:00091461220.011
positive regulation of smooth muscle cell proliferationGO:0048661510.011
Rat
protein oligomerizationGO:00512591910.011
response to metal ionGO:00100382530.011
lipid storageGO:001991510.011
regulation of tube sizeGO:0035150890.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
positive regulation of cell projection organizationGO:00313461110.011
homeostatic processGO:00425923310.011
Rat
nucleoside triphosphate metabolic processGO:00091411440.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
positive regulation of cellular catabolic processGO:0031331710.011
regulation of hormone secretionGO:00468831060.011
purine nucleotide biosynthetic processGO:0006164830.011
glycosyl compound catabolic processGO:19016581260.011
immune system processGO:00023762040.011
cellular response to lipidGO:00713962010.011
gamete generationGO:00072761240.011
neuropeptide signaling pathwayGO:0007218290.011
maintenance of locationGO:0051235170.011
positive regulation of transferase activityGO:0051347810.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
cellular component morphogenesisGO:00329891550.010
lipid metabolic processGO:00066292830.010
nucleotide biosynthetic processGO:0009165980.010
positive regulation of secretion by cellGO:19035321280.010
regulation of anatomical structure morphogenesisGO:00226031410.010
response to radiationGO:00093141370.010
protein dephosphorylationGO:0006470380.010
neurological system processGO:00508772190.010
cellular response to external stimulusGO:00714961180.010
regulation of cellular response to stressGO:0080135490.010
negative regulation of cell cycle phase transitionGO:190198840.010
positive regulation of mapk cascadeGO:0043410920.010
regulation of canonical wnt signaling pathwayGO:006082840.010
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulumGO:001088040.010

Akr1b10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012
nervous system diseaseDOID:86300.012
central nervous system diseaseDOID:33100.012
disease of metabolismDOID:001466700.011