IMP: Integrative Multi-species Prediction

Rattus norvegicus

30 known processes

Tas1r3

taste receptor, type 1, member 3

(Aliases: T1r3)

RGD: 620539
Ensembl: ENSRNOG00000019589
Entrez: 170634
UniProtKB: Q923K1

Process Predictions
Disease Predictions

Tas1r3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to nutrient levels	GO:0031667	370	0.152	Rat
homeostatic process	GO:0042592	331	0.143	Rat
immune system process	GO:0002376	204	0.126
response to external biotic stimulus	GO:0043207	221	0.123
response to extracellular stimulus	GO:0009991	380	0.108	Rat
response to other organism	GO:0051707	220	0.107
chemical homeostasis	GO:0048878	292	0.104	Rat
negative regulation of chronic inflammatory response	GO:0002677	2	0.074
response to corticosteroid	GO:0031960	235	0.073
lipid metabolic process	GO:0006629	283	0.073
carboxylic acid metabolic process	GO:0019752	289	0.065
response to bacterium	GO:0009617	200	0.060
g protein coupled receptor signaling pathway	GO:0007186	242	0.060
t cell tolerance induction	GO:0002517	3	0.060
response to biotic stimulus	GO:0009607	226	0.058
cellular ion homeostasis	GO:0006873	184	0.057	Rat
catabolic process	GO:0009056	351	0.054
aging	GO:0007568	241	0.053
positive regulation of multicellular organismal process	GO:0051240	387	0.053	Rat
anion transmembrane transport	GO:0098656	77	0.052
divalent inorganic cation homeostasis	GO:0072507	165	0.050	Rat
macromolecule localization	GO:0033036	252	0.049
transmembrane transport	GO:0055085	412	0.049	Rat
protein phosphorylation	GO:0006468	345	0.049
response to chromate	GO:0046687	3	0.049
oxoacid metabolic process	GO:0043436	290	0.048
regulation of hormone secretion	GO:0046883	106	0.048	Rat
multi organism reproductive process	GO:0044703	262	0.045
carbohydrate metabolic process	GO:0005975	130	0.045
regulation of system process	GO:0044057	208	0.044	Rat
regulation of hormone levels	GO:0010817	187	0.044	Rat
single organism catabolic process	GO:0044712	283	0.043
single organism carbohydrate metabolic process	GO:0044723	118	0.042
organic acid metabolic process	GO:0006082	292	0.041
single organism intracellular transport	GO:1902582	166	0.041
cellular response to organic cyclic compound	GO:0071407	202	0.040	Rat
response to lipopolysaccharide	GO:0032496	191	0.039
defense response	GO:0006952	194	0.038
response to metal ion	GO:0010038	253	0.037	Rat
monovalent inorganic cation transport	GO:0015672	172	0.037
regulation of metal ion transport	GO:0010959	118	0.037	Rat
regulation of blood circulation	GO:1903522	110	0.033	Rat
cellular chemical homeostasis	GO:0055082	247	0.033	Rat
central nervous system development	GO:0007417	311	0.033
inorganic ion transmembrane transport	GO:0098660	229	0.033
response to axon injury	GO:0048678	59	0.033
positive regulation of biosynthetic process	GO:0009891	319	0.033
apoptotic process	GO:0006915	381	0.032	Rat
response to inorganic substance	GO:0010035	377	0.032	Rat
response to vitamin	GO:0033273	131	0.031	Rat
response to decreased oxygen levels	GO:0036293	237	0.031	Rat
response to glucocorticoid	GO:0051384	223	0.031
response to toxic substance	GO:0009636	133	0.031
positive regulation of transport	GO:0051050	245	0.031	Rat
hormone transport	GO:0009914	121	0.030	Rat
regulation of secretion	GO:0051046	224	0.030	Rat
response to transition metal nanoparticle	GO:1990267	122	0.029
response to estrogen	GO:0043627	232	0.029
cellular homeostasis	GO:0019725	252	0.029	Rat
multicellular organism reproduction	GO:0032504	233	0.029
regulation of cellular localization	GO:0060341	263	0.028	Rat
reproduction	GO:0000003	245	0.026
regulation of phosphorus metabolic process	GO:0051174	349	0.026
inflammatory response to antigenic stimulus	GO:0002437	18	0.025
positive regulation of molecular function	GO:0044093	230	0.025
female pregnancy	GO:0007565	122	0.025
cell activation	GO:0001775	97	0.024
cellular carbohydrate metabolic process	GO:0044262	72	0.024
intracellular signal transduction	GO:0035556	314	0.024	Rat
cellular response to oxygen containing compound	GO:1901701	386	0.024	Rat
neuron death	GO:0070997	127	0.024
neurological system process	GO:0050877	219	0.024
proteolysis	GO:0006508	175	0.023
lipid transport	GO:0006869	61	0.023
response to oxygen levels	GO:0070482	265	0.023	Rat
dna replication	GO:0006260	37	0.023
cellular response to endogenous stimulus	GO:0071495	377	0.023	Rat
calcium ion homeostasis	GO:0055074	162	0.022	Rat
positive regulation of cell development	GO:0010720	176	0.022
regulation of anatomical structure size	GO:0090066	135	0.022	Rat
sodium ion transport	GO:0006814	82	0.022
response to estradiol	GO:0032355	164	0.022
glycerolipid metabolic process	GO:0046486	67	0.021
cation homeostasis	GO:0055080	195	0.021	Rat
regulation of ion transport	GO:0043269	245	0.021	Rat
ion homeostasis	GO:0050801	212	0.021	Rat
sexual reproduction	GO:0019953	148	0.021
cellular amine metabolic process	GO:0044106	38	0.021
regulation of nervous system development	GO:0051960	264	0.020
establishment of protein localization	GO:0045184	141	0.020
reproductive process	GO:0022414	372	0.020
intracellular transport	GO:0046907	185	0.020
cation transport	GO:0006812	382	0.020	Rat
phosphatidylinositol dephosphorylation	GO:0046856	4	0.020
vesicle mediated transport	GO:0016192	181	0.019
single organism reproductive process	GO:0044702	297	0.019
amine metabolic process	GO:0009308	38	0.019
secretion by cell	GO:0032940	248	0.019	Rat
response to molecule of bacterial origin	GO:0002237	194	0.018
response to carbohydrate	GO:0009743	183	0.018	Rat
cytoplasmic transport	GO:0016482	115	0.018
positive regulation of cellular amine metabolic process	GO:0033240	3	0.018
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.018	Rat
organ induction	GO:0001759	1	0.018
organic hydroxy compound metabolic process	GO:1901615	115	0.018
regulation of cellular amino acid metabolic process	GO:0006521	2	0.017
anatomical structure morphogenesis	GO:0009653	298	0.017	Rat
response to hypoxia	GO:0001666	231	0.017	Rat
positive regulation of cellular amino acid metabolic process	GO:0045764	1	0.017
head development	GO:0060322	247	0.017
somatostatin receptor signaling pathway	GO:0038169	4	0.017
adenylate cyclase modulating g protein coupled receptor signaling pathway	GO:0007188	51	0.017	Rat
positive regulation of cellular biosynthetic process	GO:0031328	295	0.017
developmental process involved in reproduction	GO:0003006	159	0.016
cellular cation homeostasis	GO:0030003	180	0.016	Rat
cellular ketone metabolic process	GO:0042180	51	0.016
positive regulation of protein metabolic process	GO:0051247	178	0.016
maintenance of location	GO:0051235	17	0.016
regulation of transmembrane transport	GO:0034762	122	0.016	Rat
cellular amino acid metabolic process	GO:0006520	107	0.016
sensory perception	GO:0007600	101	0.016
neutrophil apoptotic process	GO:0001781	4	0.016
cellular response to hexose stimulus	GO:0071331	65	0.016	Rat
regulation of phosphatidylinositol dephosphorylation	GO:0060304	1	0.016
response to cytokine	GO:0034097	215	0.016
metal ion transport	GO:0030001	289	0.016	Rat
growth	GO:0040007	165	0.016
single organism biosynthetic process	GO:0044711	342	0.016
response to acid chemical	GO:0001101	222	0.016
regulation of vasculature development	GO:1901342	44	0.016
inflammatory response	GO:0006954	150	0.015
ion transmembrane transport	GO:0034220	365	0.015	Rat
embryo implantation	GO:0007566	15	0.015
cellular component assembly	GO:0022607	360	0.015
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.015
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.015
nuclear import	GO:0051170	35	0.015
defense response to gram negative bacterium	GO:0050829	3	0.015
xenobiotic metabolic process	GO:0006805	19	0.015
cellular nitrogen compound catabolic process	GO:0044270	163	0.015
regulation of cellular ketone metabolic process	GO:0010565	27	0.014
cell cell signaling	GO:0007267	335	0.014	Rat
response to nutrient	GO:0007584	248	0.014	Rat
positive regulation of catalytic activity	GO:0043085	184	0.014
regulation of neurogenesis	GO:0050767	247	0.014
cellular response to organonitrogen compound	GO:0071417	197	0.014	Rat
response to increased oxygen levels	GO:0036296	45	0.014
regulation of homeostatic process	GO:0032844	101	0.014
brain development	GO:0007420	247	0.014
circulatory system process	GO:0003013	183	0.014	Rat
regulation of immune system process	GO:0002682	123	0.014
cellular catabolic process	GO:0044248	295	0.014
synaptic transmission	GO:0007268	235	0.014
somatostatin signaling pathway	GO:0038170	4	0.014
cytosolic calcium ion homeostasis	GO:0051480	140	0.013
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.013
cellular macromolecule localization	GO:0070727	122	0.013
regulation of dna metabolic process	GO:0051052	60	0.013
cellular lipid metabolic process	GO:0044255	208	0.013
membrane organization	GO:0061024	94	0.013
immune response	GO:0006955	104	0.013
single organism cellular localization	GO:1902580	102	0.013
sequestering of metal ion	GO:0051238	9	0.013
reactive nitrogen species metabolic process	GO:2001057	1	0.013
regulation of response to external stimulus	GO:0032101	106	0.013	Rat
monosaccharide metabolic process	GO:0005996	61	0.013
regulation of cellular amine metabolic process	GO:0033238	8	0.013
positive regulation of neurogenesis	GO:0050769	165	0.012
negative regulation of long term synaptic potentiation	GO:1900272	1	0.012
programmed cell death	GO:0012501	392	0.012	Rat
protein localization	GO:0008104	191	0.012
feeding behavior	GO:0007631	53	0.012
regulation of cell activation	GO:0050865	50	0.012
regulation of phosphate metabolic process	GO:0019220	349	0.012
positive regulation of protein phosphorylation	GO:0001934	135	0.012
multicellular organismal reproductive process	GO:0048609	233	0.012
hematopoietic progenitor cell differentiation	GO:0002244	2	0.012
angioblast cell migration	GO:0035476	1	0.012
multicellular organism growth	GO:0035264	1	0.012
regulation of insulin secretion	GO:0050796	65	0.012	Rat
regulation of intracellular transport	GO:0032386	65	0.012
positive regulation of cell proliferation	GO:0008284	249	0.012	Rat
regulation of neural precursor cell proliferation	GO:2000177	16	0.012
protein transport	GO:0015031	132	0.012
multi multicellular organism process	GO:0044706	138	0.012
regulation of programmed cell death	GO:0043067	341	0.012
spermatogenesis	GO:0007283	99	0.012
development of primary sexual characteristics	GO:0045137	107	0.012
regulation of hydrolase activity	GO:0051336	143	0.012
organic hydroxy compound biosynthetic process	GO:1901617	51	0.011
regulation of cellular carbohydrate metabolic process	GO:0010675	39	0.011
monocarboxylic acid metabolic process	GO:0032787	152	0.011
detection of chemical stimulus involved in sensory perception of bitter taste	GO:0001580	4	0.011
lipid storage	GO:0019915	1	0.011
smooth muscle contraction	GO:0006939	37	0.011
response to xenobiotic stimulus	GO:0009410	23	0.011
catecholamine metabolic process	GO:0006584	19	0.011
cellular response to xenobiotic stimulus	GO:0071466	19	0.011
regulation of immunoglobulin production	GO:0002637	4	0.011
positive regulation of cell differentiation	GO:0045597	217	0.011
negative regulation of response to stimulus	GO:0048585	155	0.011
positive regulation of hydrolase activity	GO:0051345	86	0.011
nucleic acid templated transcription	GO:0097659	379	0.011
protein heterooligomerization	GO:0051291	89	0.011
regulation of nucleic acid templated transcription	GO:1903506	380	0.011
adult locomotory behavior	GO:0008344	4	0.011
regulation of behavior	GO:0050795	61	0.011	Rat
positive regulation of nucleotide metabolic process	GO:0045981	91	0.011
carbohydrate derivative metabolic process	GO:1901135	346	0.011
regulation of leukocyte activation	GO:0002694	45	0.011
endocrine hormone secretion	GO:0060986	21	0.011
glucose homeostasis	GO:0042593	75	0.011	Rat
male gamete generation	GO:0048232	99	0.011
positive regulation of gene expression	GO:0010628	244	0.011
sequestering of calcium ion	GO:0051208	8	0.011
response to radiation	GO:0009314	137	0.011
response to monosaccharide	GO:0034284	159	0.011	Rat
protein complex biogenesis	GO:0070271	263	0.010
fatty acid metabolic process	GO:0006631	99	0.010
positive regulation of apoptotic process	GO:0043065	154	0.010
reactive oxygen species biosynthetic process	GO:1903409	8	0.010
regulation of blood vessel size	GO:0050880	89	0.010	Rat
circadian rhythm	GO:0007623	88	0.010
blood circulation	GO:0008015	183	0.010	Rat
response to mineralocorticoid	GO:0051385	49	0.010
defense response to other organism	GO:0098542	17	0.010
organophosphate metabolic process	GO:0019637	370	0.010

Tas1r3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.019
disease of anatomical entity	DOID:7	0.019
sensory system disease	DOID:0050155	0.019
eye and adnexa disease	DOID:1492	0.019
eye disease	DOID:5614	0.019
retinal disease	DOID:5679	0.019
disease of mental health	DOID:150	0.017
substance related disorder	DOID:303	0.017

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