Rattus norvegicus

0 known processes

Igh-6

immunoglobulin heavy chain 6

(Aliases: RGD1359202,IgM,MGC125059)

Igh-6 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023762040.497
leukocyte activationGO:0045321760.298
immune responseGO:00069551040.270
regulation of transcription dna templatedGO:00063553740.258
regulation of rna biosynthetic processGO:20011413810.210
t cell activationGO:0042110290.209
myeloid leukocyte activationGO:0002274360.199
cell activationGO:0001775970.190
homeostatic processGO:00425923310.188
positive regulation of biosynthetic processGO:00098913190.183
cytokine mediated signaling pathwayGO:0019221430.178
response to cytokineGO:00340972150.170
regulation of nucleic acid templated transcriptionGO:19035063800.163
response to inorganic substanceGO:00100353770.158
carboxylic acid metabolic processGO:00197522890.158
regulation of rna metabolic processGO:00512523910.152
b cell differentiationGO:003018320.146
positive regulation of nucleobase containing compound metabolic processGO:00459353190.140
negative regulation of nitrogen compound metabolic processGO:00511721610.131
transcription dna templatedGO:00063513770.131
rna biosynthetic processGO:00327743800.122
response to biotic stimulusGO:00096072260.122
organic acid metabolic processGO:00060822920.116
neuron differentiationGO:00301823680.115
negative regulation of nucleic acid templated transcriptionGO:19035071170.112
positive regulation of transcription dna templatedGO:00458931970.110
regulation of multicellular organismal developmentGO:20000263760.109
positive regulation of cellular biosynthetic processGO:00313282950.109
cellular response to acid chemicalGO:0071229750.108
response to growth factorGO:00708481890.103
angioblast cell migrationGO:003547610.100
nucleic acid templated transcriptionGO:00976593790.099
response to external biotic stimulusGO:00432072210.098
programmed cell deathGO:00125013920.097
regulation of angiogenesisGO:0045765390.097
positive regulation of cell proliferationGO:00082842490.095
negative regulation of biosynthetic processGO:00098901680.092
organophosphate metabolic processGO:00196373700.089
taxisGO:0042330670.088
regulation of cell differentiationGO:00455953200.084
rna metabolic processGO:00160704060.083
t cell differentiationGO:003021790.082
anatomical structure morphogenesisGO:00096532980.080
transcription from rna polymerase ii promoterGO:00063662520.079
negative regulation of cellular metabolic processGO:00313242810.077
oxoacid metabolic processGO:00434362900.075
proteolysisGO:00065081750.074
negative regulation of multicellular organismal processGO:00512412030.073
sequestering of metal ionGO:005123890.073
regulation of cellular ketone metabolic processGO:0010565270.072
positive regulation of locomotionGO:00400171020.071
negative regulation of chronic inflammatory responseGO:000267720.071
regulation of secretionGO:00510462240.070
positive regulation of multicellular organismal processGO:00512403870.069
histamine production involved in inflammatory responseGO:000234930.067
negative regulation of macromolecule biosynthetic processGO:00105581480.067
response to molecule of bacterial originGO:00022371940.066
regulation of neurogenesisGO:00507672470.065
protein autophosphorylationGO:0046777660.065
positive regulation of leukocyte activationGO:0002696300.063
positive regulation of cellular component movementGO:00512721020.063
leukocyte differentiationGO:0002521300.062
protein phosphorylationGO:00064683450.062
cellular ketone metabolic processGO:0042180510.062
hemopoiesisGO:0030097340.061
regulation of phosphate metabolic processGO:00192203490.061
regulation of cellular localizationGO:00603412630.060
regulation of homeostatic processGO:00328441010.058
positive regulation of developmental processGO:00510942830.058
intracellular transportGO:00469071850.057
apoptotic processGO:00069153810.057
regulation of metal ion transportGO:00109591180.056
chemotaxisGO:0006935660.055
head developmentGO:00603222470.055
regulation of cellular protein metabolic processGO:00322682670.054
olfactory learningGO:000835510.054
positive regulation of cell developmentGO:00107201760.053
positive regulation of humoral immune responseGO:000292220.052
response to lipopolysaccharideGO:00324961910.052
secretion by cellGO:00329402480.052
regulation of cellular amino acid metabolic processGO:000652120.050
secretionGO:00469033070.050
regulation of synaptic plasticityGO:0048167700.049
positive regulation of immunoglobulin productionGO:000263940.049
regulation of cell developmentGO:00602842630.049
response to oxygen levelsGO:00704822650.048
regulation of neuron differentiationGO:00456642080.047
regulation of ion transportGO:00432692450.047
enzyme linked receptor protein signaling pathwayGO:00071671160.047
regulation of cellular amine metabolic processGO:003323880.046
positive regulation of secretion by cellGO:19035321280.046
response to metal ionGO:00100382530.046
regulation of necroptotic processGO:006054420.046
divalent metal ion transportGO:00708381320.045
negative regulation of rna biosynthetic processGO:19026791180.044
positive regulation of nitrogen compound metabolic processGO:00511733340.044
positive regulation of leukocyte degranulationGO:004330240.043
organophosphate biosynthetic processGO:00904071430.043
positive regulation of gene expressionGO:00106282440.043
salivary gland developmentGO:000743130.043
regulation of anatomical structure morphogenesisGO:00226031410.043
negative regulation of programmed cell deathGO:00430691830.042
developmental process involved in reproductionGO:00030061590.042
vesicle mediated transportGO:00161921810.042
regulation of leukocyte activationGO:0002694450.042
regulation of cell proliferationGO:00421273590.042
cellular amino acid metabolic processGO:00065201070.042
positive regulation of secretionGO:00510471400.042
cellular response to oxygen containing compoundGO:19017013860.042
norepinephrine secretionGO:0048243160.041
chemical homeostasisGO:00488782920.040
regulation of locomotionGO:00400121480.040
positive regulation of cellular protein metabolic processGO:00322701670.040
neuron projection developmentGO:00311752730.039
cellular catabolic processGO:00442482950.039
angiogenesisGO:0001525530.039
antigen receptor mediated signaling pathwayGO:005085110.038
positive regulation of macromolecule biosynthetic processGO:00105572470.038
carbohydrate derivative metabolic processGO:19011353460.038
cell cell signalingGO:00072673350.037
regulation of programmed cell deathGO:00430673410.037
negative regulation of nucleobase containing compound metabolic processGO:00459341530.037
regulation of hydrolase activityGO:00513361430.037
circulatory system developmentGO:00723591340.036
t cell receptor signaling pathwayGO:005085210.036
negative regulation of cellular component organizationGO:0051129830.036
cellular response to cytokine stimulusGO:00713451270.036
positive regulation of nucleic acid templated transcriptionGO:19035081970.035
regulation of nervous system developmentGO:00519602640.035
cellular lipid metabolic processGO:00442552080.035
learning or memoryGO:0007611900.035
intracellular signal transductionGO:00355563140.035
amine metabolic processGO:0009308380.034
response to peptide hormoneGO:00434342780.034
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.034
negative regulation of rna metabolic processGO:00512531230.034
cation transportGO:00068123820.034
negative regulation of homeostatic processGO:0032845470.034
cellular amine metabolic processGO:0044106380.034
synaptic growth at neuromuscular junctionGO:005112410.034
positive regulation of nervous system developmentGO:00519621780.033
response to other organismGO:00517072200.033
lymphocyte differentiationGO:0030098100.033
negative regulation of metabolic processGO:00098923310.033
response to fatty acidGO:0070542650.033
single organism behaviorGO:00447081300.032
positive regulation of rna metabolic processGO:00512542030.032
locomotionGO:00400112370.031
catecholamine secretionGO:0050432330.031
regulation of t cell activationGO:0050863230.031
regulation of catalytic activityGO:00507903040.030
positive regulation of immune system processGO:0002684900.030
negative regulation of cellular biosynthetic processGO:00313271610.030
response to hexoseGO:00097461440.030
cellular homeostasisGO:00197252520.030
cell motilityGO:00488702020.030
cellular calcium ion homeostasisGO:00068741600.030
single organism catabolic processGO:00447122830.029
negative regulation of long term synaptic potentiationGO:190027210.029
mast cell migrationGO:009753140.029
immune effector processGO:0002252530.029
response to decreased oxygen levelsGO:00362932370.029
regulation of phosphorus metabolic processGO:00511743490.028
cellular chemical homeostasisGO:00550822470.028
cognitionGO:0050890920.027
blood vessel morphogenesisGO:0048514580.027
protein secretionGO:0009306340.027
cellular cation homeostasisGO:00300031800.027
regulation of apoptotic processGO:00429813350.027
regulation of secretion by cellGO:19035302080.027
establishment of protein localizationGO:00451841410.027
regulation of signal transductionGO:00099663180.027
innate immune responseGO:0045087350.027
regulation of molecular functionGO:00650093980.027
regulation of immune system processGO:00026821230.026
negative regulation of transcription dna templatedGO:00458921160.026
positive regulation of gamma delta t cell activationGO:004664510.026
ion homeostasisGO:00508012120.026
regulation of vasculature developmentGO:1901342440.026
cell projection organizationGO:00300303020.026
neuron developmentGO:00486662860.026
ribonucleotide metabolic processGO:00092592310.026
ribose phosphate metabolic processGO:00196932350.025
positive regulation of norepinephrine secretionGO:001070140.025
regulation of neuron projection developmentGO:00109751610.025
dna metabolic processGO:0006259960.025
t cell proliferationGO:0042098190.025
response to hypoxiaGO:00016662310.025
organelle localizationGO:0051640550.025
positive regulation of immune responseGO:0050778420.025
regulation of b cell differentiationGO:004557710.025
chronic inflammatory response to non antigenic stimulusGO:000254510.024
response to reactive oxygen speciesGO:00003021200.024
sequestering of calcium ionGO:005120880.024
protein processingGO:0016485680.024
t cell chemotaxisGO:001081820.024
response to acid chemicalGO:00011012220.024
positive regulation of cell deathGO:00109421840.024
somatic diversification of immune receptors via germline recombination within a single locusGO:000256220.024
tissue developmentGO:00098882520.024
positive regulation of rna biosynthetic processGO:19026801970.023
response to hydrogen peroxideGO:0042542890.023
multicellular organismal homeostasisGO:0048871490.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.023
necroptotic processGO:007026620.023
positive regulation of neurogenesisGO:00507691650.023
positive regulation of cellular amine metabolic processGO:003324030.022
cellular metal ion homeostasisGO:00068751720.022
lipid metabolic processGO:00066292830.022
salivary gland morphogenesisGO:000743510.022
central nervous system developmentGO:00074173110.022
positive regulation of molecular functionGO:00440932300.022
regulation of protein metabolic processGO:00512462890.022
biological adhesionGO:00226101100.022
cellular component biogenesisGO:00440853680.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
nucleotide metabolic processGO:00091172790.021
regulation of t cell differentiationGO:004558070.021
metanephric tubule morphogenesisGO:007217320.021
positive regulation of cellular amino acid metabolic processGO:004576410.021
regulation of immune responseGO:0050776550.021
nucleoside phosphate metabolic processGO:00067532830.021
regulation of cell activationGO:0050865500.020
exocytosisGO:0006887600.020
maintenance of locationGO:0051235170.020
multicellular organism growthGO:003526410.020
response to bacteriumGO:00096172000.020
blood vessel developmentGO:0001568690.020
macromolecule localizationGO:00330362520.020
peptidyl amino acid modificationGO:00181931260.020
epithelial cell differentiationGO:0030855710.020
negative regulation of macromolecule metabolic processGO:00106052600.020
regulation of chronic inflammatory responseGO:000267630.020
negative regulation of transportGO:00510511360.019
divalent inorganic cation transportGO:00725111340.019
regulation of transcription from rna polymerase ii promoterGO:00063572340.019
metal ion transportGO:00300012890.019
cellular response to stressGO:00335542690.019
anatomical structure formation involved in morphogenesisGO:0048646830.019
mapk cascadeGO:00001651400.019
cell projection morphogenesisGO:00488581230.019
negative regulation of innate immune responseGO:004582440.019
cellular component morphogenesisGO:00329891550.019
female pregnancyGO:00075651220.019
lysosome localizationGO:0032418100.019
positive regulation of cell differentiationGO:00455972170.018
phospholipid biosynthetic processGO:0008654290.018
negative regulation of developmental processGO:00510931250.018
regulation of cell projection organizationGO:00313441750.018
organic substance catabolic processGO:19015753160.018
peptidyl tyrosine modificationGO:0018212720.018
synaptic transmissionGO:00072682350.018
cellular response to growth factor stimulusGO:00713631620.018
leukocyte activation involved in immune responseGO:0002366160.018
glycerolipid metabolic processGO:0046486670.018
carbohydrate metabolic processGO:00059751300.018
positive regulation of dna metabolic processGO:0051054390.018
neuron apoptotic processGO:0051402880.017
response to hyperoxiaGO:0055093450.017
lymphocyte activationGO:0046649430.017
regulation of norepinephrine secretionGO:0014061150.017
regulation of cell motilityGO:20001451310.017
regulation of cellular component organizationGO:00511283680.017
cytoplasmic transportGO:00164821150.017
activation of phospholipase d activityGO:003158420.016
regulation of ion homeostasisGO:2000021630.016
divalent inorganic cation homeostasisGO:00725071650.016
positive regulation of transportGO:00510502450.016
positive regulation of cytokine productionGO:0001819420.016
positive regulation of protein kinase activityGO:0045860730.016
membrane organizationGO:0061024940.016
catabolic processGO:00090563510.016
metal ion homeostasisGO:00550651860.016
cytosolic calcium ion homeostasisGO:00514801400.016
organelle organizationGO:00069962660.016
regulation of neuronal synaptic plasticityGO:0048168310.016
lipid biosynthetic processGO:00086101280.016
nucleoside phosphate catabolic processGO:19012921400.015
response to purine containing compoundGO:00140741260.015
cellular defense responseGO:000696820.015
negative regulation of chronic inflammatory response to non antigenic stimulusGO:000288110.015
regulation of reactive oxygen species metabolic processGO:2000377260.015
reactive oxygen species metabolic processGO:0072593370.015
small molecule biosynthetic processGO:00442831240.015
myeloid cell activation involved in immune responseGO:0002275130.015
cellular lipid catabolic processGO:0044242370.015
negative regulation of sequestering of calcium ionGO:0051283250.015
cellular response to lipidGO:00713962010.014
gastrulationGO:000736920.014
ventral spinal cord interneuron specificationGO:002152120.014
regulation of cell morphogenesisGO:0022604770.014
positive regulation of isotype switchingGO:004583010.014
negative regulation of response to stimulusGO:00485851550.014
regulation of alpha beta t cell activationGO:004663420.014
fatty acid catabolic processGO:0009062260.014
immune response activating signal transductionGO:0002757150.014
regulation of synaptic transmissionGO:00508041410.014
protein localizationGO:00081041910.014
negative regulation of gene expressionGO:00106291990.014
immune response regulating cell surface receptor signaling pathwayGO:0002768100.014
regulation of isotype switching to igg isotypesGO:004830210.014
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.014
response to monosaccharideGO:00342841590.014
regulation of phosphorylationGO:00423252480.014
activation of protein kinase b activityGO:003214830.014
amine transportGO:0015837570.014
response to nutrient levelsGO:00316673700.014
single organism intracellular transportGO:19025821660.014
metanephric tubule developmentGO:007217040.014
cell cell signaling involved in cell fate commitmentGO:004516820.013
response to glucoseGO:00097491360.013
immune system developmentGO:0002520410.013
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.013
somatic cell dna recombinationGO:001644420.013
positive regulation of leukocyte differentiationGO:1902107130.013
b cell activation involved in immune responseGO:000231210.013
response to oxidative stressGO:00069791860.013
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.013
immunoglobulin mediated immune responseGO:001606440.013
response to radiationGO:00093141370.013
response to carbohydrateGO:00097431830.013
response to magnesium ionGO:0032026200.013
positive regulation of catalytic activityGO:00430851840.013
regulation of neutrophil apoptotic processGO:003302940.013
b cell mediated immunityGO:001972440.013
neuron projection morphogenesisGO:00488121220.013
development of primary male sexual characteristicsGO:0046546590.013
response to molecule of fungal originGO:000223830.013
positive regulation of cell motilityGO:2000147970.013
leukocyte mediated immunityGO:0002443280.013
ribonucleotide catabolic processGO:00092611360.013
purine nucleotide metabolic processGO:00061632290.013
cellular response to endogenous stimulusGO:00714953770.013
regulation of calcium ion transportGO:0051924770.013
positive regulation of protein metabolic processGO:00512471780.013
interleukin 12 productionGO:003261530.013
negative regulation of cell deathGO:00605482290.013
multi organism reproductive processGO:00447032620.013
mitotic spindle organizationGO:000705220.012
multicellular organism reproductionGO:00325042330.012
positive regulation of kinase activityGO:0033674770.012
response to woundingGO:00096112540.012
regulation of mapk cascadeGO:00434081160.012
cellular macromolecule catabolic processGO:0044265290.012
response to interleukin 15GO:007067240.012
olfactory behaviorGO:004204820.012
purine nucleotide catabolic processGO:00061951360.012
negative regulation of neutrophil apoptotic processGO:003303030.012
organophosphate catabolic processGO:00464341480.012
positive regulation of phosphorus metabolic processGO:00105622620.012
negative regulation of viral processGO:004852540.012
regulation of immunoglobulin productionGO:000263740.012
metanephric epithelium developmentGO:007220740.012
chemokine mediated signaling pathwayGO:007009850.012
negative regulation of neuron deathGO:1901215690.012
response to peptideGO:19016522920.012
positive regulation of phosphate metabolic processGO:00459372620.012
single organism reproductive processGO:00447022970.012
positive regulation of catecholamine secretionGO:0033605130.012
positive regulation of protein tyrosine kinase activityGO:006109820.012
regulation of t cell proliferationGO:0042129170.012
neutrophil apoptotic processGO:000178140.012
positive regulation of mesenchymal cell proliferationGO:000205340.012
lymphocyte migrationGO:007267630.012
regulation of intracellular transportGO:0032386650.012
positive regulation of calcium ion transportGO:0051928360.012
cellular divalent inorganic cation homeostasisGO:00725031620.012
organic acid catabolic processGO:0016054490.012
regulation of establishment of protein localizationGO:0070201690.012
cell migrationGO:00164771970.012
calcium ion homeostasisGO:00550741620.012
response to axon injuryGO:0048678590.012
regulation of proteolysisGO:0030162660.012
response to increased oxygen levelsGO:0036296450.012
cellular response to reactive oxygen speciesGO:0034614550.012
regulation of cytokine productionGO:0001817560.011
digestive system developmentGO:0055123410.011
positive regulation of phosphorylationGO:00423271770.011
single organism membrane organizationGO:0044802740.011
protein transportGO:00150311320.011
cell adhesionGO:00071551100.011
reproductionGO:00000032450.011
positive regulation of leukocyte mediated immunityGO:0002705130.011
purine containing compound metabolic processGO:00725212530.011
protein dephosphorylationGO:0006470380.011
regulation of cellular carbohydrate metabolic processGO:0010675390.011
negative regulation of cellular protein metabolic processGO:00322691060.011
carboxylic acid biosynthetic processGO:0046394830.011
inflammatory cell apoptotic processGO:000692550.011
peptidyl tyrosine phosphorylationGO:0018108720.011
mast cell chemotaxisGO:000255140.011
tube developmentGO:0035295890.011
negative regulation of cell communicationGO:00106481580.011
neurotrophin productionGO:003289820.011
t cell tolerance inductionGO:000251730.011
regulation of purine nucleotide metabolic processGO:19005421150.011
positive regulation of alpha beta t cell activationGO:004663520.011
cellular response to lipopolysaccharideGO:0071222550.011
regulation of homotypic cell cell adhesionGO:003411040.011
positive regulation of necroptotic processGO:006054520.011
negative regulation of leukocyte apoptotic processGO:200010740.011
regulation of macrophage chemotaxisGO:001075820.011
fc receptor mediated stimulatory signaling pathwayGO:000243130.011
cellular response to transforming growth factor beta stimulusGO:0071560410.011
behaviorGO:00076102050.011
localization of cellGO:00516742020.011
negative regulation of protein modification processGO:0031400520.011
positive regulation of camp mediated signalingGO:004395020.011
regulation of lymphocyte activationGO:0051249340.011
establishment of organelle localizationGO:0051656370.011
monocarboxylic acid transportGO:0015718520.011
negative regulation of molecular functionGO:00440921330.011
t cell selectionGO:004505810.010
cardiovascular system developmentGO:00723581340.010
negative regulation of protein maturationGO:1903318470.010
cellular response to biotic stimulusGO:0071216590.010
spindle organizationGO:000705120.010
dendrite developmentGO:0016358720.010
programmed necrotic cell deathGO:009730020.010
cation homeostasisGO:00550801950.010
positive regulation of neuron differentiationGO:00456661260.010
leukocyte proliferationGO:0070661290.010
regulation of endopeptidase activityGO:0052548510.010
axis specificationGO:000979840.010
positive regulation of programmed cell deathGO:00430681570.010
gliogenesisGO:0042063930.010
vasculature developmentGO:0001944700.010
antigen processing and presentationGO:001988220.010
single organism organelle organizationGO:19025891800.010
positive regulation of synaptic transmissionGO:0050806620.010
cellular carbohydrate metabolic processGO:0044262720.010
neutrophil homeostasisGO:000178040.010
cellular component movementGO:00069282480.010
phospholipid metabolic processGO:0006644610.010
nucleobase containing compound catabolic processGO:00346551520.010

Igh-6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
musculoskeletal system diseaseDOID:1700.028
connective tissue diseaseDOID:6500.028
bone diseaseDOID:008000100.012
nervous system diseaseDOID:86300.011