Rattus norvegicus

17 known processes

Pkn1

protein kinase N1

(Aliases: PAK-1,Prkcl1)

Pkn1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
metal ion transportGO:00300012890.088
protein phosphorylationGO:00064683450.083
cation transportGO:00068123820.080
organophosphate catabolic processGO:00464341480.077
homeostatic processGO:00425923310.070
Mouse
purine containing compound metabolic processGO:00725212530.066
cation transmembrane transportGO:00986552630.066
regulation of molecular functionGO:00650093980.066
Mouse
positive regulation of response to stimulusGO:00485842850.064
Fly
transmembrane transportGO:00550854120.055
regulation of ion transportGO:00432692450.054
catabolic processGO:00090563510.050
nucleoside phosphate metabolic processGO:00067532830.048
intracellular signal transductionGO:00355563140.048
nucleic acid templated transcriptionGO:00976593790.047
Human
divalent metal ion transportGO:00708381320.045
nucleotide metabolic processGO:00091172790.044
organophosphate metabolic processGO:00196373700.044
purine ribonucleotide metabolic processGO:00091502270.044
organonitrogen compound biosynthetic processGO:19015661670.043
negative regulation of nitrogen compound metabolic processGO:00511721610.043
organelle organizationGO:00069962660.041
Human Fly
ribonucleotide metabolic processGO:00092592310.039
regulation of catalytic activityGO:00507903040.039
Mouse
single organism biosynthetic processGO:00447113420.039
nucleobase containing small molecule metabolic processGO:00550863160.039
macromolecular complex subunit organizationGO:00439333390.038
Human
positive regulation of transportGO:00510502450.038
response to inorganic substanceGO:00100353770.037
purine nucleotide metabolic processGO:00061632290.037
cation homeostasisGO:00550801950.037
carbohydrate derivative metabolic processGO:19011353460.037
positive regulation of cell communicationGO:00106472710.036
regulation of purine nucleotide metabolic processGO:19005421150.035
positive regulation of nucleobase containing compound metabolic processGO:00459353190.035
metal ion homeostasisGO:00550651860.035
cellular divalent inorganic cation homeostasisGO:00725031620.035
positive regulation of molecular functionGO:00440932300.034
rna biosynthetic processGO:00327743800.034
Human
reproductive processGO:00224143720.034
programmed cell deathGO:00125013920.033
Mouse
neuron differentiationGO:00301823680.033
monovalent inorganic cation transportGO:00156721720.032
positive regulation of signalingGO:00230562700.032
regulation of hydrolase activityGO:00513361430.032
response to other organismGO:00517072200.031
immune system processGO:00023762040.031
Mouse
regulation of rna metabolic processGO:00512523910.031
Human
nucleoside triphosphate metabolic processGO:00091411440.031
cell projection organizationGO:00300303020.031
ion homeostasisGO:00508012120.031
calcium ion transportGO:00068161310.030
small molecule biosynthetic processGO:00442831240.030
response to metal ionGO:00100382530.030
lipid metabolic processGO:00066292830.030
heterocycle catabolic processGO:00467001670.030
negative regulation of metabolic processGO:00098923310.030
Mouse
cellular calcium ion homeostasisGO:00068741600.030
divalent inorganic cation transportGO:00725111340.029
regulation of metal ion transportGO:00109591180.029
response to extracellular stimulusGO:00099913800.029
oxoacid metabolic processGO:00434362900.029
cellular ion homeostasisGO:00068731840.029
store operated calcium entryGO:000211520.029
calcium ion homeostasisGO:00550741620.029
cellular chemical homeostasisGO:00550822470.029
cellular ketone metabolic processGO:0042180510.029
cellular amine metabolic processGO:0044106380.029
regulation of cellular amine metabolic processGO:003323880.029
chemical homeostasisGO:00488782920.028
regulation of intracellular signal transductionGO:19025312180.028
cellular response to endogenous stimulusGO:00714953770.028
positive regulation of developmental processGO:00510942830.027
regulation of signal transductionGO:00099663180.027
organophosphate biosynthetic processGO:00904071430.027
amine metabolic processGO:0009308380.027
transcription dna templatedGO:00063513770.027
Human
cellular homeostasisGO:00197252520.026
transcription from rna polymerase ii promoterGO:00063662520.026
Human
regulation of phosphorus metabolic processGO:00511743490.026
Mouse
regulation of multicellular organismal developmentGO:20000263760.026
cellular cation homeostasisGO:00300031800.026
regulation of cell differentiationGO:00455953200.026
ribonucleoside triphosphate metabolic processGO:00091991410.026
response to fatty acidGO:0070542650.026
single organism catabolic processGO:00447122830.026
ribonucleoside triphosphate catabolic processGO:00092031220.026
purine nucleoside triphosphate metabolic processGO:00091441410.025
regulation of mapk cascadeGO:00434081160.025
divalent inorganic cation homeostasisGO:00725071650.025
cellular response to stressGO:00335542690.025
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.025
chromosome organizationGO:0051276360.025
Human
purine ribonucleoside metabolic processGO:00461281680.025
neuron developmentGO:00486662860.025
purine ribonucleoside triphosphate metabolic processGO:00092051400.025
positive regulation of cellular biosynthetic processGO:00313282950.025
nucleoside metabolic processGO:00091161790.025
neurological system processGO:00508772190.024
response to acid chemicalGO:00011012220.024
inorganic cation transmembrane transportGO:00986622020.024
regulation of rna biosynthetic processGO:20011413810.024
Human
nucleoside phosphate catabolic processGO:19012921400.024
cellular amino acid metabolic processGO:00065201070.024
response to purine containing compoundGO:00140741260.024
small gtpase mediated signal transductionGO:0007264360.024
regulation of cellular ketone metabolic processGO:0010565270.024
purine nucleoside metabolic processGO:00422781690.024
inorganic ion transmembrane transportGO:00986602290.024
defense responseGO:00069521940.024
response to nutrient levelsGO:00316673700.024
response to peptideGO:19016522920.024
regulation of phosphate metabolic processGO:00192203490.023
Mouse
ribose phosphate metabolic processGO:00196932350.023
response to bacteriumGO:00096172000.023
peptidyl amino acid modificationGO:00181931260.023
Human
ion transmembrane transportGO:00342203650.023
single organism organelle organizationGO:19025891800.022
Human Fly
negative regulation of signalingGO:00230571570.022
negative regulation of natural killer cell mediated immunityGO:000271640.022
response to peptide hormoneGO:00434342780.022
negative regulation of neuron differentiationGO:0045665620.022
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.022
carboxylic acid metabolic processGO:00197522890.021
positive regulation of transcription dna templatedGO:00458931970.021
multi multicellular organism processGO:00447061380.021
cellular response to oxygen containing compoundGO:19017013860.021
neuron projection developmentGO:00311752730.021
regulation of phosphorylationGO:00423252480.021
Mouse
ribonucleoside catabolic processGO:00424541260.021
response to oxidative stressGO:00069791860.021
lipid biosynthetic processGO:00086101280.021
sensory perceptionGO:00076001010.021
nucleobase containing compound catabolic processGO:00346551520.021
learning or memoryGO:0007611900.021
organic cyclic compound catabolic processGO:19013611750.021
regulation of protein kinase activityGO:00458591050.021
Mouse
ribonucleoside metabolic processGO:00091191740.021
cellular response to external stimulusGO:00714961180.021
cytosolic calcium ion homeostasisGO:00514801400.021
cell type specific apoptotic processGO:00972851340.021
Mouse
cellular metal ion homeostasisGO:00068751720.020
protein complex subunit organizationGO:00718223020.020
central nervous system developmentGO:00074173110.020
response to biotic stimulusGO:00096072260.020
purine ribonucleotide biosynthetic processGO:0009152810.020
organic substance catabolic processGO:19015753160.020
glycosyl compound metabolic processGO:19016571820.020
response to nutrientGO:00075842480.020
alcohol biosynthetic processGO:0046165380.020
regulation of protein phosphorylationGO:00019321830.020
Mouse
rna metabolic processGO:00160704060.020
Human
regulation of cell proliferationGO:00421273590.020
Mouse
positive regulation of macromolecule biosynthetic processGO:00105572470.020
negative regulation of innate immune responseGO:004582440.020
response to cytokineGO:00340972150.020
regulation of cellular amino acid metabolic processGO:000652120.020
organic acid metabolic processGO:00060822920.020
regulation of nucleotide metabolic processGO:00061401170.020
head developmentGO:00603222470.019
regulation of cellular protein metabolic processGO:00322682670.019
Mouse
nitrogen compound transportGO:00717052290.019
agingGO:00075682410.019
positive regulation of phosphate metabolic processGO:00459372620.019
multicellular organism reproductionGO:00325042330.019
positive regulation of purine nucleotide metabolic processGO:1900544910.019
single organism carbohydrate metabolic processGO:00447231180.019
negative regulation of cellular metabolic processGO:00313242810.019
Mouse
negative regulation of biosynthetic processGO:00098901680.019
regulation of immune system processGO:00026821230.019
Mouse
multi organism reproductive processGO:00447032620.019
positive regulation of nitrogen compound metabolic processGO:00511733340.019
positive regulation of cell differentiationGO:00455972170.019
carbohydrate derivative biosynthetic processGO:19011371240.019
apoptotic processGO:00069153810.019
Mouse
positive regulation of immune system processGO:0002684900.019
chromatin assembly or disassemblyGO:000633310.019
purine ribonucleoside catabolic processGO:00461301240.018
organonitrogen compound catabolic processGO:19015651790.018
organic acid biosynthetic processGO:0016053830.018
purine nucleoside catabolic processGO:00061521240.018
carbohydrate derivative catabolic processGO:19011361470.018
regulation of nucleic acid templated transcriptionGO:19035063800.018
Human
purine ribonucleoside triphosphate catabolic processGO:00092071220.018
response to growth factorGO:00708481890.018
response to external biotic stimulusGO:00432072210.018
positive regulation of cell deathGO:00109421840.018
alcohol metabolic processGO:0006066770.018
cellular response to lipidGO:00713962010.018
locomotionGO:00400112370.018
Human
aromatic compound catabolic processGO:00194391680.017
positive regulation of multicellular organismal processGO:00512403870.017
positive regulation of phosphorus metabolic processGO:00105622620.017
regulation of cellular component organizationGO:00511283680.017
negative regulation of cell deathGO:00605482290.017
positive regulation of cellular amine metabolic processGO:003324030.017
ribonucleotide catabolic processGO:00092611360.017
regulation of cell developmentGO:00602842630.017
protein localizationGO:00081041910.017
positive regulation of programmed cell deathGO:00430681570.017
embryonic pattern specificationGO:000988010.017
nucleoside catabolic processGO:00091641260.017
regulation of transmembrane transporter activityGO:0022898490.017
nucleotide catabolic processGO:00091661390.017
mitotic spindle organizationGO:000705220.017
positive regulation of rna biosynthetic processGO:19026801970.017
cellular nitrogen compound catabolic processGO:00442701630.017
cellular response to nitrogen compoundGO:19016992100.017
regulation of calcium ion transportGO:0051924770.017
regulation of cell projection organizationGO:00313441750.017
cellular component biogenesisGO:00440853680.017
single organism intracellular transportGO:19025821660.017
purine ribonucleotide catabolic processGO:00091541360.016
positive regulation of nucleic acid templated transcriptionGO:19035081970.016
regulation of homeostatic processGO:00328441010.016
positive regulation of ion transportGO:0043270940.016
response to reactive oxygen speciesGO:00003021200.016
cellular catabolic processGO:00442482950.016
cellular response to organic cyclic compoundGO:00714072020.016
regulation of ion transmembrane transportGO:00347651210.016
negative regulation of cell communicationGO:00106481580.016
regulation of neurogenesisGO:00507672470.016
organic hydroxy compound biosynthetic processGO:1901617510.016
regulation of programmed cell deathGO:00430673410.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
spindle organizationGO:000705120.016
response to campGO:0051591910.016
purine containing compound catabolic processGO:00725231380.016
regulation of cation channel activityGO:2001257230.016
signal transduction by phosphorylationGO:00230141440.016
axis specificationGO:000979840.016
positive regulation of signal transductionGO:00099671750.015
response to woundingGO:00096112540.015
Fly
regulation of neuron differentiationGO:00456642080.015
response to organophosphorusGO:00466831020.015
intracellular transportGO:00469071850.015
cellular component assemblyGO:00226073600.015
cellular lipid metabolic processGO:00442552080.015
regulation of membrane potentialGO:00423911100.015
macromolecule localizationGO:00330362520.015
cellular component movementGO:00069282480.015
Human
regulation of transmembrane transportGO:00347621220.015
purine nucleotide biosynthetic processGO:0006164830.015
guanosine containing compound metabolic processGO:1901068740.015
anterior posterior pattern specificationGO:000995210.015
cell motilityGO:00488702020.015
Human
female pregnancyGO:00075651220.015
reproductionGO:00000032450.015
glycosyl compound catabolic processGO:19016581260.014
cell cycleGO:00070491010.014
response to lipopolysaccharideGO:00324961910.014
regulation of transcription dna templatedGO:00063553740.014
Human
regulation of cellular localizationGO:00603412630.014
sensory organ developmentGO:0007423740.014
g protein coupled receptor signaling pathwayGO:00071862420.014
positive regulation of cell proliferationGO:00082842490.014
regulation of defense responseGO:0031347680.014
regulation of hormone levelsGO:00108171870.014
negative regulation of response to stimulusGO:00485851550.014
cellular macromolecule localizationGO:00707271220.014
single organism reproductive processGO:00447022970.014
positive regulation of intracellular signal transductionGO:19025331380.014
salivary gland developmentGO:000743130.014
positive regulation of cytosolic calcium ion concentrationGO:00072041220.014
positive regulation of catalytic activityGO:00430851840.013
behaviorGO:00076102050.013
macromolecular complex assemblyGO:00650032730.013
carboxylic acid biosynthetic processGO:0046394830.013
ras protein signal transductionGO:0007265290.013
positive regulation of cellular component organizationGO:00511302000.013
regulation of gtpase activityGO:0043087570.013
brain developmentGO:00074202470.013
regulation of neuron projection developmentGO:00109751610.013
positive regulation of phosphorylationGO:00423271770.013
multicellular organismal reproductive processGO:00486092330.013
protein complex biogenesisGO:00702712630.013
regulation of ion transmembrane transporter activityGO:0032412480.013
cyclic nucleotide biosynthetic processGO:0009190630.013
response to decreased oxygen levelsGO:00362932370.013
asymmetric protein localizationGO:000810520.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
response to monosaccharideGO:00342841590.013
regulation of purine nucleotide catabolic processGO:0033121650.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.012
positive regulation of t cell mediated cytotoxicityGO:000191640.012
response to glucocorticoidGO:00513842230.012
regulation of kinase activityGO:00435491170.012
Mouse
regulation of protein metabolic processGO:00512462890.012
Mouse
nucleoside phosphate biosynthetic processGO:19012931020.012
cellular response to cytokine stimulusGO:00713451270.012
cellular response to peptide hormone stimulusGO:00713751200.012
purine nucleoside triphosphate catabolic processGO:00091461220.012
regulation of immune responseGO:0050776550.012
Mouse
response to ethanolGO:00454711620.012
regulation of lipid metabolic processGO:0019216680.012
membrane organizationGO:0061024940.012
potassium ion transportGO:0006813970.012
vesicle mediated transportGO:00161921810.012
regulation of locomotionGO:00400121480.012
Human
regulation of nucleotide catabolic processGO:0030811650.012
wound healingGO:00420601220.012
Fly
defense response to gram negative bacteriumGO:005082930.012
proteolysisGO:00065081750.012
carboxylic acid transportGO:00469421150.012
positive regulation of apoptotic processGO:00430651540.012
nucleoside triphosphate catabolic processGO:00091431230.012
positive regulation of calcium ion transportGO:0051928360.012
positive regulation of cell developmentGO:00107201760.012
anion transportGO:00068201780.012
cyclic nucleotide metabolic processGO:0009187800.012
fatty acid metabolic processGO:0006631990.012
establishment of protein localizationGO:00451841410.012
negative regulation of multicellular organismal processGO:00512412030.012
heart morphogenesisGO:000300730.012
sequestering of calcium ionGO:005120880.012
organic hydroxy compound metabolic processGO:19016151150.012
single organism cellular localizationGO:19025801020.012
regulation of cell motilityGO:20001451310.012
Human
protein oligomerizationGO:00512591910.012
monocarboxylic acid metabolic processGO:00327871520.012
response to calcium ionGO:0051592590.012
response to insulinGO:00328681330.012
response to mechanical stimulusGO:00096121340.011
purine nucleoside monophosphate metabolic processGO:0009126840.011
cellular response to abiotic stimulusGO:0071214850.011
reactive oxygen species biosynthetic processGO:190340980.011
positive regulation of mapk cascadeGO:0043410920.011
negative regulation of macromolecule metabolic processGO:00106052600.011
Mouse
purine ribonucleoside monophosphate catabolic processGO:0009169550.011
circulatory system processGO:00030131830.011
muscle structure developmentGO:0061061870.011
regenerationGO:00310991630.011
cellular response to peptideGO:19016531330.011
gtp catabolic processGO:0006184710.011
cellular response to extracellular stimulusGO:0031668730.011
negative regulation of cell differentiationGO:0045596990.011
reactive nitrogen species metabolic processGO:200105710.011
regulation of blood circulationGO:19035221100.011
negative regulation of rna metabolic processGO:00512531230.011
sexual reproductionGO:00199531480.011
negative regulation of catalytic activityGO:00430861030.011
Mouse
neuron deathGO:00709971270.011
anatomical structure morphogenesisGO:00096532980.011
Mouse Fly
cell cell signalingGO:00072673350.011
positive regulation of nervous system developmentGO:00519621780.011
gtp metabolic processGO:0046039720.011
organic anion transportGO:00157111320.011
response to oxygen levelsGO:00704822650.011
negative regulation of gene expressionGO:00106291990.011
response to osmotic stressGO:0006970420.011
Mouse
peptidyl tyrosine modificationGO:0018212720.011
regulation of sodium ion transportGO:0002028210.011
regulation of anatomical structure sizeGO:00900661350.011
positive regulation of homeostatic processGO:0032846490.011
negative regulation of transcription dna templatedGO:00458921160.011
growthGO:00400071650.011
positive regulation of immune responseGO:0050778420.011
positive regulation of cellular component movementGO:00512721020.010
organic acid transportGO:00158491160.010
response to alkaloidGO:00432791320.010
negative regulation of programmed cell deathGO:00430691830.010
maintenance of locationGO:0051235170.010
positive regulation of biosynthetic processGO:00098913190.010
positive regulation of response to external stimulusGO:0032103510.010
regulation of catabolic processGO:00098941130.010
chromatin modificationGO:0016568330.010
Human
regulation of nervous system developmentGO:00519602640.010
response to radiationGO:00093141370.010
sequestering of metal ionGO:005123890.010
regulation of apoptotic processGO:00429813350.010
response to carbohydrateGO:00097431830.010
inflammatory responseGO:00069541500.010
response to corticosteroidGO:00319602350.010
regulation of cell migrationGO:00303341280.010
ribonucleotide biosynthetic processGO:0009260850.010

Pkn1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.012
disease of metabolismDOID:001466700.012
nervous system diseaseDOID:86300.011
disease of anatomical entityDOID:700.011