Rattus norvegicus

123 known processes

Tsc1

tuberous sclerosis 1

Tsc1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intracellular signal transductionGO:00355563140.491
positive regulation of multicellular organismal processGO:00512403870.167
regulation of phosphate metabolic processGO:00192203490.150
positive regulation of phosphate metabolic processGO:00459372620.101
regulation of programmed cell deathGO:00430673410.098
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.097
regulation of molecular functionGO:00650093980.090
regulation of nucleic acid templated transcriptionGO:19035063800.090
response to inorganic substanceGO:00100353770.086
regulation of rna metabolic processGO:00512523910.079
regulation of rna biosynthetic processGO:20011413810.078
regulation of catalytic activityGO:00507903040.077
regulation of multicellular organismal developmentGO:20000263760.074
positive regulation of molecular functionGO:00440932300.068
regulation of intracellular signal transductionGO:19025312180.068
positive regulation of nucleobase containing compound metabolic processGO:00459353190.067
cellular response to endogenous stimulusGO:00714953770.066
positive regulation of response to stimulusGO:00485842850.064
brain developmentGO:00074202470.062
positive regulation of macromolecule biosynthetic processGO:00105572470.061
regulation of cell differentiationGO:00455953200.061
rna biosynthetic processGO:00327743800.060
negative regulation of cellular metabolic processGO:00313242810.060
nucleic acid templated transcriptionGO:00976593790.060
regulation of transcription dna templatedGO:00063553740.059
rna metabolic processGO:00160704060.058
enzyme linked receptor protein signaling pathwayGO:00071671160.057
positive regulation of cellular biosynthetic processGO:00313282950.054
transcription from rna polymerase ii promoterGO:00063662520.053
regulation of protein metabolic processGO:00512462890.053
protein phosphorylationGO:00064683450.051
neuron apoptotic processGO:0051402880.051
regulation of phosphorylationGO:00423252480.050
positive regulation of phosphorylationGO:00423271770.050
macromolecular complex assemblyGO:00650032730.050
positive regulation of biosynthetic processGO:00098913190.049
regulation of signal transductionGO:00099663180.047
regulation of phosphorus metabolic processGO:00511743490.045
central nervous system developmentGO:00074173110.045
regulation of cellular protein metabolic processGO:00322682670.044
protein complex assemblyGO:00064612630.044
multicellular organismal reproductive processGO:00486092330.043
positive regulation of cell proliferationGO:00082842490.043
negative regulation of cell deathGO:00605482290.043
transcription dna templatedGO:00063513770.041
positive regulation of cellular protein metabolic processGO:00322701670.041
head developmentGO:00603222470.041
nucleobase containing compound catabolic processGO:00346551520.040
locomotionGO:00400112370.040
negative regulation of macromolecule metabolic processGO:00106052600.040
positive regulation of nitrogen compound metabolic processGO:00511733340.039
small gtpase mediated signal transductionGO:0007264360.039
regulation of neuron deathGO:19012141150.039
regulation of kinase activityGO:00435491170.038
cell cycleGO:00070491010.038
regulation of immune system processGO:00026821230.038
regulation of transcription from rna polymerase ii promoterGO:00063572340.038
organic substance catabolic processGO:19015753160.037
cellular component assemblyGO:00226073600.036
protein oligomerizationGO:00512591910.036
reproductionGO:00000032450.036
nucleoside phosphate metabolic processGO:00067532830.035
regulation of protein phosphorylationGO:00019321830.035
positive regulation of intracellular signal transductionGO:19025331380.035
cellular catabolic processGO:00442482950.034
response to campGO:0051591910.034
protein complex biogenesisGO:00702712630.033
positive regulation of cell deathGO:00109421840.033
response to acid chemicalGO:00011012220.033
negative regulation of nitrogen compound metabolic processGO:00511721610.033
positive regulation of nucleic acid templated transcriptionGO:19035081970.033
positive regulation of protein metabolic processGO:00512471780.033
protein complex subunit organizationGO:00718223020.033
response to nutrient levelsGO:00316673700.032
positive regulation of signal transductionGO:00099671750.032
immune system processGO:00023762040.032
regulation of nervous system developmentGO:00519602640.032
mapk cascadeGO:00001651400.031
catabolic processGO:00090563510.031
single organism catabolic processGO:00447122830.031
response to decreased oxygen levelsGO:00362932370.031
cellular response to oxygen containing compoundGO:19017013860.030
negative regulation of metabolic processGO:00098923310.030
cell migrationGO:00164771970.030
carbohydrate derivative metabolic processGO:19011353460.029
negative regulation of macromolecule biosynthetic processGO:00105581480.029
regulation of protein modification processGO:00313991940.029
protein transportGO:00150311320.029
regulation of cell developmentGO:00602842630.029
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.029
positive regulation of programmed cell deathGO:00430681570.028
programmed cell deathGO:00125013920.028
regulation of neurogenesisGO:00507672470.028
positive regulation of signalingGO:00230562700.028
response to oxygen levelsGO:00704822650.028
response to peptideGO:19016522920.028
positive regulation of developmental processGO:00510942830.027
response to peptide hormoneGO:00434342780.027
negative regulation of molecular functionGO:00440921330.027
cellular protein localizationGO:00346131220.026
response to extracellular stimulusGO:00099913800.026
leukocyte activationGO:0045321760.026
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.026
positive regulation of phosphorus metabolic processGO:00105622620.026
macromolecule localizationGO:00330362520.026
macromolecular complex subunit organizationGO:00439333390.026
antral ovarian follicle growthGO:000154730.026
carbohydrate derivative catabolic processGO:19011361470.026
cell type specific apoptotic processGO:00972851340.026
regulation of cell proliferationGO:00421273590.026
pro t cell differentiationGO:000257210.025
positive regulation of gene expressionGO:00106282440.025
negative regulation of cellular biosynthetic processGO:00313271610.025
negative regulation of biosynthetic processGO:00098901680.025
adult locomotory behaviorGO:000834440.025
regulation of transferase activityGO:00513381230.025
negative regulation of protein metabolic processGO:00512481140.025
ras protein signal transductionGO:0007265290.024
response to insulinGO:00328681330.024
cellular lipid metabolic processGO:00442552080.024
apoptotic processGO:00069153810.024
cellular response to nitrogen compoundGO:19016992100.024
positive regulation of catalytic activityGO:00430851840.024
cellular component movementGO:00069282480.024
positive regulation of apoptotic processGO:00430651540.023
cellular response to insulin stimulusGO:0032869810.023
positive regulation of protein phosphorylationGO:00019341350.023
amine metabolic processGO:0009308380.023
positive regulation of rna biosynthetic processGO:19026801970.023
regulation of apoptotic processGO:00429813350.023
negative regulation of rna metabolic processGO:00512531230.023
membrane organizationGO:0061024940.022
regulation of hydrolase activityGO:00513361430.022
response to woundingGO:00096112540.022
cell motilityGO:00488702020.022
regulation of cellular component organizationGO:00511283680.021
regulation of neuron apoptotic processGO:0043523830.021
regenerationGO:00310991630.021
positive regulation of neurogenesisGO:00507691650.021
nucleoside metabolic processGO:00091161790.021
heterocycle catabolic processGO:00467001670.021
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.020
cellular response to hormone stimulusGO:00328702470.020
anatomical structure morphogenesisGO:00096532980.020
negative regulation of cell proliferationGO:00082851190.020
positive regulation of cell communicationGO:00106472710.020
regulation of small gtpase mediated signal transductionGO:0051056480.020
negative regulation of cellular protein metabolic processGO:00322691060.020
purine containing compound catabolic processGO:00725231380.020
organophosphate metabolic processGO:00196373700.020
nucleoside phosphate catabolic processGO:19012921400.020
cellular component biogenesisGO:00440853680.020
negative regulation of programmed cell deathGO:00430691830.019
multi organism reproductive processGO:00447032620.019
purine ribonucleotide catabolic processGO:00091541360.019
negative regulation of response to stimulusGO:00485851550.019
positive regulation of cell developmentGO:00107201760.019
positive regulation of cell projection organizationGO:00313461110.019
tissue developmentGO:00098882520.019
positive regulation of rna metabolic processGO:00512542030.019
signal transduction by phosphorylationGO:00230141440.019
regulation of hormone levelsGO:00108171870.018
regulation of mapk cascadeGO:00434081160.018
negative regulation of signal transductionGO:0009968830.018
regulation of response to stressGO:00801341260.018
agingGO:00075682410.018
response to radiationGO:00093141370.018
positive regulation of cell differentiationGO:00455972170.018
developmental process involved in reproductionGO:00030061590.018
smooth muscle cell proliferationGO:0048659770.018
cell projection organizationGO:00300303020.017
purine nucleoside metabolic processGO:00422781690.017
rhythmic processGO:00485111560.017
response to growth factorGO:00708481890.017
glycosyl compound metabolic processGO:19016571820.017
tube developmentGO:0035295890.017
positive regulation of cellular component organizationGO:00511302000.017
cellular response to peptideGO:19016531330.017
epithelial cell differentiationGO:0030855710.017
single organism reproductive processGO:00447022970.017
positive regulation of nervous system developmentGO:00519621780.017
intracellular transportGO:00469071850.016
intracellular protein transportGO:0006886790.016
neurological system processGO:00508772190.016
regulation of neuron projection developmentGO:00109751610.016
organic cyclic compound catabolic processGO:19013611750.016
regulation of cell projection organizationGO:00313441750.016
regulation of cell motilityGO:20001451310.015
protein heterooligomerizationGO:0051291890.015
cellular response to stressGO:00335542690.015
negative regulation of nucleic acid templated transcriptionGO:19035071170.015
multicellular organism growthGO:003526410.015
negative regulation of rna biosynthetic processGO:19026791180.015
response to metal ionGO:00100382530.015
protein localizationGO:00081041910.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
organ regenerationGO:00311001010.015
regulation of cellular amino acid metabolic processGO:000652120.014
organelle organizationGO:00069962660.014
response to estrogenGO:00436272320.014
ribonucleotide catabolic processGO:00092611360.014
purine nucleotide metabolic processGO:00061632290.014
regulation of defense responseGO:0031347680.014
immune responseGO:00069551040.014
response to molecule of bacterial originGO:00022371940.014
regulation of catabolic processGO:00098941130.014
purine ribonucleoside metabolic processGO:00461281680.014
response to retinoic acidGO:0032526630.014
organophosphate catabolic processGO:00464341480.014
spindle organizationGO:000705120.014
purine nucleotide catabolic processGO:00061951360.014
positive regulation of protein modification processGO:00314011420.014
negative regulation of cell differentiationGO:0045596990.014
neuronal action potentialGO:0019228350.014
regulation of cellular ketone metabolic processGO:0010565270.013
transmission of nerve impulseGO:0019226420.013
nucleobase containing small molecule metabolic processGO:00550863160.013
establishment of protein localizationGO:00451841410.013
cellular response to organonitrogen compoundGO:00714171970.013
protein homooligomerizationGO:0051260910.013
response to toxic substanceGO:00096361330.013
hematopoietic progenitor cell differentiationGO:000224420.013
neuron differentiationGO:00301823680.013
positive regulation of isotype switchingGO:004583010.013
multicellular organism reproductionGO:00325042330.013
single organism intracellular transportGO:19025821660.013
regulation of cellular amine metabolic processGO:003323880.013
neuron developmentGO:00486662860.013
negative regulation of catalytic activityGO:00430861030.013
defense responseGO:00069521940.013
maintenance of locationGO:0051235170.012
dephosphorylationGO:0016311980.012
nucleoside triphosphate catabolic processGO:00091431230.012
proteolysisGO:00065081750.012
epithelium developmentGO:0060429960.012
response to glucocorticoidGO:00513842230.012
aromatic compound catabolic processGO:00194391680.012
cellular response to growth factor stimulusGO:00713631620.012
cellular response to peptide hormone stimulusGO:00713751200.012
nucleoside triphosphate metabolic processGO:00091411440.012
localization of cellGO:00516742020.012
positive regulation of immunoglobulin productionGO:000263940.012
response to organophosphorusGO:00466831020.012
cellular ketone metabolic processGO:0042180510.012
peptidyl tyrosine modificationGO:0018212720.012
growthGO:00400071650.012
cellular amine metabolic processGO:0044106380.012
anion transportGO:00068201780.012
macromolecule catabolic processGO:0009057580.012
negative regulation of gene expressionGO:00106291990.012
gamete generationGO:00072761240.012
response to external biotic stimulusGO:00432072210.012
positive regulation of neuron differentiationGO:00456661260.012
positive regulation of transferase activityGO:0051347810.012
cellular amino acid metabolic processGO:00065201070.012
protein processingGO:0016485680.012
insulin like growth factor receptor signaling pathwayGO:004800930.012
regulation of epithelial cell proliferationGO:0050678490.011
response to lipopolysaccharideGO:00324961910.011
regulation of nucleotide metabolic processGO:00061401170.011
cellular homeostasisGO:00197252520.011
g protein coupled receptor signaling pathwayGO:00071862420.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
b cell activation involved in immune responseGO:000231210.011
regulation of immunoglobulin productionGO:000263740.011
nitrogen compound transportGO:00717052290.011
nucleoside catabolic processGO:00091641260.011
negative regulation of multicellular organismal processGO:00512412030.011
regulation of lipid metabolic processGO:0019216680.011
muscle cell proliferationGO:0033002840.011
synaptic growth at neuromuscular junctionGO:005112410.011
negative regulation of intracellular signal transductionGO:1902532380.011
response to nutrientGO:00075842480.011
response to bacteriumGO:00096172000.011
cytoplasmic transportGO:00164821150.011
regulation of protein serine threonine kinase activityGO:0071900640.011
axis specificationGO:000979840.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
intracellular receptor signaling pathwayGO:0030522350.010
response to oxidative stressGO:00069791860.010
response to hypoxiaGO:00016662310.010
regulation of mrna splicing via spliceosomeGO:004802430.010
gastrulationGO:000736920.010
positive regulation of mapk cascadeGO:0043410920.010
sequestering of metal ionGO:005123890.010
regulation of cell cycleGO:0051726730.010
cellular component morphogenesisGO:00329891550.010
reproductive processGO:00224143720.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.010

Tsc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.025
disease of anatomical entityDOID:700.025
disease of metabolismDOID:001466700.016
central nervous system diseaseDOID:33100.011