Rattus norvegicus

0 known processes

Isl2

ISL LIM homeobox 2

Isl2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
macromolecular complex subunit organizationGO:00439333390.174
rhythmic processGO:00485111560.174
neurological system processGO:00508772190.171
protein complex subunit organizationGO:00718223020.157
protein complex biogenesisGO:00702712630.126
metal ion transportGO:00300012890.125
cation transportGO:00068123820.118
response to extracellular stimulusGO:00099913800.114
cell cell signalingGO:00072673350.112
Rat
cellular component assemblyGO:00226073600.108
forebrain developmentGO:0030900980.106
phasic smooth muscle contractionGO:001482130.105
nitrogen compound transportGO:00717052290.105
Rat
macromolecular complex assemblyGO:00650032730.103
cellular component biogenesisGO:00440853680.101
telencephalon developmentGO:0021537620.095
response to ethanolGO:00454711620.095
protein oligomerizationGO:00512591910.086
negative regulation of nitrogen compound metabolic processGO:00511721610.085
positive regulation of biosynthetic processGO:00098913190.085
Rat Fly
reproductive processGO:00224143720.083
Worm
cell cycleGO:00070491010.081
rna biosynthetic processGO:00327743800.080
Rat Fly
anion transportGO:00068201780.078
regulation of ion transportGO:00432692450.077
protein complex assemblyGO:00064612630.076
single organism behaviorGO:00447081300.075
intracellular signal transductionGO:00355563140.070
regulation of cell proliferationGO:00421273590.070
cellular protein localizationGO:00346131220.068
secretionGO:00469033070.068
Rat
tissue developmentGO:00098882520.067
Rat Fly
programmed cell deathGO:00125013920.064
negative regulation of cellular biosynthetic processGO:00313271610.064
learning or memoryGO:0007611900.064
multicellular organism reproductionGO:00325042330.063
positive regulation of multicellular organismal processGO:00512403870.062
protein phosphorylationGO:00064683450.062
sensory perceptionGO:00076001010.061
potassium ion transportGO:0006813970.060
regulation of system processGO:00440572080.060
regulation of secretionGO:00510462240.059
Rat
behaviorGO:00076102050.058
positive regulation of phosphate metabolic processGO:00459372620.057
regulation of cellular component organizationGO:00511283680.056
regulation of rna metabolic processGO:00512523910.056
Rat Fly
regulation of rna biosynthetic processGO:20011413810.055
Rat Fly
regulation of membrane potentialGO:00423911100.054
urinary bladder smooth muscle contractionGO:001483240.053
regulation of body fluid levelsGO:0050878900.053
n methyl d aspartate receptor clusteringGO:009711420.052
cellular macromolecule localizationGO:00707271220.052
heart developmentGO:0007507720.052
Fly
nucleobase containing small molecule metabolic processGO:00550863160.051
response to estradiolGO:00323551640.051
regulation of cell developmentGO:00602842630.050
Mouse
tonic smooth muscle contractionGO:001482040.050
regulation of transcription dna templatedGO:00063553740.050
Rat Fly
vascular process in circulatory systemGO:0003018960.050
positive regulation of cell developmentGO:00107201760.050
carboxylic acid transportGO:00469421150.049
anterior posterior pattern specificationGO:000995210.048
Fly
synaptic transmissionGO:00072682350.048
transmembrane transportGO:00550854120.048
positive regulation of cell proliferationGO:00082842490.048
organic anion transportGO:00157111320.046
regulation of behaviorGO:0050795610.045
rna metabolic processGO:00160704060.045
Rat Fly
neuron developmentGO:00486662860.045
Zebrafish Mouse Rat Fly
macromolecule localizationGO:00330362520.045
secretion by cellGO:00329402480.044
Rat
locomotionGO:00400112370.043
Zebrafish Mouse Worm Fly
neuron projection developmentGO:00311752730.043
Zebrafish Mouse Rat Fly
purine nucleoside metabolic processGO:00422781690.043
purine nucleotide metabolic processGO:00061632290.042
purine nucleoside triphosphate catabolic processGO:00091461220.042
oxoacid metabolic processGO:00434362900.041
carbohydrate derivative metabolic processGO:19011353460.041
negative regulation of biosynthetic processGO:00098901680.041
synapse organizationGO:0050808460.040
circadian rhythmGO:0007623880.040
response to foodGO:0032094270.040
enzyme linked receptor protein signaling pathwayGO:00071671160.040
Fly
urinary tract smooth muscle contractionGO:001484840.039
cellular amino acid metabolic processGO:00065201070.039
purine ribonucleotide catabolic processGO:00091541360.038
negative regulation of developmental processGO:00510931250.038
Mouse
organophosphate metabolic processGO:00196373700.038
negative regulation of cell differentiationGO:0045596990.038
Mouse
positive regulation of nitrogen compound metabolic processGO:00511733340.038
Rat Fly
central nervous system developmentGO:00074173110.038
Mouse
apoptotic processGO:00069153810.037
multicellular organismal reproductive processGO:00486092330.037
positive regulation of nucleobase containing compound metabolic processGO:00459353190.037
Rat Fly
cellular ketone metabolic processGO:0042180510.037
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.036
small gtpase mediated signal transductionGO:0007264360.036
negative regulation of macromolecule metabolic processGO:00106052600.036
positive regulation of cellular component organizationGO:00511302000.035
protein heterooligomerizationGO:0051291890.035
purine ribonucleoside catabolic processGO:00461301240.034
transcription dna templatedGO:00063513770.034
Rat Fly
positive regulation of cytosolic calcium ion concentrationGO:00072041220.034
regulation of multicellular organismal developmentGO:20000263760.034
Mouse
regulation of cellular amine metabolic processGO:003323880.034
ribonucleoside triphosphate catabolic processGO:00092031220.034
g protein coupled receptor signaling pathwayGO:00071862420.033
response to nutrientGO:00075842480.033
positive regulation of gene expressionGO:00106282440.033
Rat Fly
cardiovascular system developmentGO:00723581340.033
Fly
regulation of developmental growthGO:0048638450.033
organophosphate catabolic processGO:00464341480.033
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.033
reproductionGO:00000032450.032
brain developmentGO:00074202470.032
regulation of cellular amino acid metabolic processGO:000652120.032
regulation of cellular component movementGO:00512701500.032
positive regulation of neurogenesisGO:00507691650.032
regulation of nucleic acid templated transcriptionGO:19035063800.031
Rat Fly
neuron fate commitmentGO:004866340.031
Zebrafish Mouse
regulation of cellular ketone metabolic processGO:0010565270.031
glycosyl compound metabolic processGO:19016571820.030
monocarboxylic acid transportGO:0015718520.030
amine metabolic processGO:0009308380.030
purine nucleotide catabolic processGO:00061951360.030
agingGO:00075682410.030
negative regulation of signalingGO:00230571570.030
Rat
organic acid metabolic processGO:00060822920.030
thyroid gland developmentGO:003087810.029
saliva secretionGO:004654130.029
purine ribonucleotide metabolic processGO:00091502270.029
nucleic acid templated transcriptionGO:00976593790.029
Rat Fly
ribonucleotide catabolic processGO:00092611360.029
negative regulation of cell developmentGO:0010721820.029
Mouse
organelle organizationGO:00069962660.029
diaphragm contractionGO:000208620.029
response to nutrient levelsGO:00316673700.028
circulatory system processGO:00030131830.028
head developmentGO:00603222470.028
Worm
neuromuscular synaptic transmissionGO:000727420.028
regulation of transmembrane transporter activityGO:0022898490.028
nucleotide metabolic processGO:00091172790.028
regulation of programmed cell deathGO:00430673410.028
multi organism reproductive processGO:00447032620.028
single organism catabolic processGO:00447122830.028
response to nicotineGO:0035094510.028
regulation of apoptotic processGO:00429813350.028
transcription from rna polymerase ii promoterGO:00063662520.027
Rat Fly
single organism organelle organizationGO:19025891800.027
regulation of cellular component biogenesisGO:0044087860.027
regulation of cell growthGO:0001558850.027
serotonin receptor signaling pathwayGO:0007210100.026
carbohydrate derivative catabolic processGO:19011361470.026
nucleoside phosphate metabolic processGO:00067532830.026
peptidyl amino acid modificationGO:00181931260.026
response to ketoneGO:19016541820.026
regulation of phosphate metabolic processGO:00192203490.026
cellular nitrogen compound catabolic processGO:00442701630.026
response to woundingGO:00096112540.026
Rat
organic substance catabolic processGO:19015753160.026
purine containing compound catabolic processGO:00725231380.026
response to estrogenGO:00436272320.026
ribonucleoside triphosphate metabolic processGO:00091991410.025
positive regulation of cell differentiationGO:00455972170.025
cell growthGO:00160491040.025
Zebrafish
embryonic skeletal system developmentGO:004870630.025
positive regulation of developmental processGO:00510942830.025
cytosolic calcium ion homeostasisGO:00514801400.025
glycosyl compound catabolic processGO:19016581260.025
regulation of tube sizeGO:0035150890.025
negative regulation of multicellular organismal processGO:00512412030.024
Mouse
organonitrogen compound catabolic processGO:19015651790.024
cation homeostasisGO:00550801950.024
acid secretionGO:0046717480.024
intracellular protein transportGO:0006886790.024
adenylate cyclase activating g protein coupled receptor signaling pathwayGO:0007189240.024
positive regulation of long term synaptic potentiationGO:190027340.024
mapk cascadeGO:00001651400.023
regulation of synaptic transmissionGO:00508041410.023
cellular amine metabolic processGO:0044106380.023
regulation of cell projection organizationGO:00313441750.023
cellular response to cytokine stimulusGO:00713451270.023
regulation of systemic arterial blood pressure by norepinephrine epinephrineGO:000199320.023
regulation of ion transmembrane transportGO:00347651210.023
cytoskeleton organizationGO:00070101110.023
carboxylic acid metabolic processGO:00197522890.023
cardiac chamber developmentGO:000320510.023
ribonucleoside catabolic processGO:00424541260.023
cellular response to lipidGO:00713962010.023
Rat
purine containing compound metabolic processGO:00725212530.023
reproductive system developmentGO:00614581280.023
Worm
negative regulation of neurogenesisGO:0050768780.022
Mouse
heterocycle catabolic processGO:00467001670.022
wound healingGO:00420601220.022
positive regulation of rna metabolic processGO:00512542030.022
Rat Fly
axonogenesisGO:0007409710.022
Zebrafish Mouse Fly
ion transmembrane transportGO:00342203650.022
purine ribonucleoside metabolic processGO:00461281680.022
positive regulation of blood pressure by epinephrine norepinephrineGO:000332120.022
purine ribonucleoside triphosphate catabolic processGO:00092071220.021
positive regulation of nervous system developmentGO:00519621780.021
single organism reproductive processGO:00447022970.021
Worm
sex differentiationGO:00075481130.021
Worm
biological adhesionGO:00226101100.021
response to lipopolysaccharideGO:00324961910.021
nucleoside metabolic processGO:00091161790.021
positive regulation of cell deathGO:00109421840.021
regulation of ion transmembrane transporter activityGO:0032412480.021
neuron differentiationGO:00301823680.021
Zebrafish Mouse Rat Fly
regulation of blood circulationGO:19035221100.021
ribonucleoside metabolic processGO:00091191740.021
muscle system processGO:00030121150.021
nucleoside catabolic processGO:00091641260.021
positive regulation of cellular amine metabolic processGO:003324030.020
regulation of neurogenesisGO:00507672470.020
Mouse
response to vitaminGO:00332731310.020
response to toxic substanceGO:00096361330.020
positive regulation of macromolecule biosynthetic processGO:00105572470.020
Rat Fly
cellular response to acid chemicalGO:0071229750.020
regulation of cellular localizationGO:00603412630.020
Rat
ossificationGO:0001503700.020
heart morphogenesisGO:000300730.020
organic cyclic compound catabolic processGO:19013611750.020
nucleoside triphosphate metabolic processGO:00091411440.020
cell projection organizationGO:00300303020.020
Zebrafish Mouse Rat Fly
nucleoside triphosphate catabolic processGO:00091431230.020
response to acid chemicalGO:00011012220.020
positive regulation of rna biosynthetic processGO:19026801970.020
Rat Fly
eye morphogenesisGO:004859240.020
positive regulation of sodium ion transportGO:0010765100.020
regulation of blood vessel sizeGO:0050880890.020
regulation of organelle organizationGO:0033043800.020
regulation of anatomical structure sizeGO:00900661350.020
calcium ion transportGO:00068161310.019
phospholipase c activating serotonin receptor signaling pathwayGO:000720820.019
organic hydroxy compound transportGO:0015850770.019
regulation of secretion by cellGO:19035302080.019
Rat
positive regulation of cellular component biogenesisGO:0044089550.019
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.019
Rat Fly
sexual reproductionGO:00199531480.019
nucleobase containing compound catabolic processGO:00346551520.019
amine transportGO:0015837570.019
response to cocaineGO:0042220390.019
regulation of cell differentiationGO:00455953200.019
Mouse
hippocampus developmentGO:0021766300.019
negative regulation of metabolic processGO:00098923310.019
homeostatic processGO:00425923310.019
Fly
metal ion homeostasisGO:00550651860.019
sensory organ developmentGO:0007423740.018
Fly
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178270.018
lipid transportGO:0006869610.018
monovalent inorganic cation transportGO:00156721720.018
development of primary sexual characteristicsGO:00451371070.018
Worm
protein localizationGO:00081041910.018
negative regulation of cell communicationGO:00106481580.018
Rat
response to growth factorGO:00708481890.018
Rat
protein homooligomerizationGO:0051260910.018
muscle cell differentiationGO:0042692520.018
Fly
response to transition metal nanoparticleGO:19902671220.018
muscle contractionGO:0006936880.018
regulation of muscle organ developmentGO:0048634260.018
negative regulation of cellular metabolic processGO:00313242810.018
transmission of nerve impulseGO:0019226420.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
cardiac ventricle developmentGO:000323110.018
regulation of muscle tissue developmentGO:1901861250.018
ribose phosphate metabolic processGO:00196932350.017
divalent metal ion transportGO:00708381320.017
cell morphogenesisGO:00009021420.017
Zebrafish Mouse Fly
muscle structure developmentGO:0061061870.017
Fly
negative regulation of nervous system developmentGO:0051961790.017
Mouse
epithelium developmentGO:0060429960.017
Rat Fly
ras protein signal transductionGO:0007265290.017
chemical homeostasisGO:00488782920.017
cellular component movementGO:00069282480.017
Zebrafish Mouse Fly
regulation of inhibitory postsynaptic membrane potentialGO:006008060.017
renal system processGO:0003014400.017
regulation of saliva secretionGO:004687730.017
organonitrogen compound biosynthetic processGO:19015661670.017
regulation of nucleotide catabolic processGO:0030811650.017
single organism cellular localizationGO:19025801020.017
positive regulation of phosphorus metabolic processGO:00105622620.017
regulation of cell cycleGO:0051726730.017
growthGO:00400071650.017
Zebrafish
response to external biotic stimulusGO:00432072210.017
regulation of metal ion transportGO:00109591180.016
muscle tissue developmentGO:0060537580.016
regulation of phosphorus metabolic processGO:00511743490.016
positive regulation of saliva secretionGO:004687830.016
cellular response to oxygen containing compoundGO:19017013860.016
nucleoside phosphate catabolic processGO:19012921400.016
positive regulation of cell projection organizationGO:00313461110.016
monoamine transportGO:0015844430.016
regulation of hydrolase activityGO:00513361430.016
positive regulation of the force of heart contraction by norepinephrineGO:000306110.016
membrane hyperpolarizationGO:0060081110.016
eye developmentGO:0001654500.016
response to alkaloidGO:00432791320.016
receptor clusteringGO:0043113130.016
regulation of neuron projection developmentGO:00109751610.016
cognitionGO:0050890920.016
smooth muscle contractionGO:0006939370.016
skeletal system developmentGO:0001501410.016
cellular metal ion homeostasisGO:00068751720.016
positive regulation of digestive system processGO:006045680.015
response to campGO:0051591910.015
signal releaseGO:00230611450.015
Rat
artery smooth muscle contractionGO:001482440.015
hormone secretionGO:00468791150.015
Rat
positive regulation of programmed cell deathGO:00430681570.015
cellular cation homeostasisGO:00300031800.015
regulation of neuron differentiationGO:00456642080.015
Mouse
phospholipid metabolic processGO:0006644610.015
one carbon compound transportGO:001975550.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
organic acid transportGO:00158491160.015
ribonucleotide metabolic processGO:00092592310.015
embryonic cranial skeleton morphogenesisGO:004870120.015
muscle cell developmentGO:0055001260.015
developmental growthGO:00485891000.015
Zebrafish
camera type eye morphogenesisGO:004859320.015
regulation of systemic arterial blood pressureGO:0003073300.015
regulation of amine transportGO:0051952540.015
renal system developmentGO:0072001670.015
Rat
regulation of sodium ion transportGO:0002028210.015
response to radiationGO:00093141370.015
localization of cellGO:00516742020.015
synaptic transmission cholinergicGO:0007271110.015
vasodilationGO:0042311440.014
behavioral response to nicotineGO:003509520.014
cell migrationGO:00164771970.014
actin cytoskeleton organizationGO:0030036730.014
embryonic pattern specificationGO:000988010.014
Fly
dopamine secretionGO:0014046150.014
choline transportGO:001587140.014
response to biotic stimulusGO:00096072260.014
inorganic cation transmembrane transportGO:00986622020.014
divalent inorganic cation transportGO:00725111340.014
regulation of cytoskeleton organizationGO:0051493490.014
lipid biosynthetic processGO:00086101280.014
organ regenerationGO:00311001010.014
purine nucleoside triphosphate metabolic processGO:00091441410.014
regulation of skeletal muscle tissue growthGO:004863130.014
regulation of excitatory postsynaptic membrane potentialGO:0060079180.014
response to carbohydrateGO:00097431830.014
regulation of appetiteGO:003209880.014
autonomic nervous system developmentGO:004848330.013
cellular response to organonitrogen compoundGO:00714171970.013
regulation of synaptic transmission gabaergicGO:0032228170.013
defense responseGO:00069521940.013
purine nucleoside catabolic processGO:00061521240.013
oxidation reduction processGO:00551143040.013
positive regulation of signalingGO:00230562700.013
Rat
regulation of response to stressGO:00801341260.013
musculoskeletal movementGO:0050881170.013
cellular response to growth factor stimulusGO:00713631620.013
Rat
positive regulation of nucleic acid templated transcriptionGO:19035081970.013
Rat Fly
ovulation cycle processGO:0022602500.013
response to cytokineGO:00340972150.013
respiratory system processGO:000301630.013
postsynaptic membrane organizationGO:000194150.013
cellular lipid metabolic processGO:00442552080.013
nucleoside monophosphate catabolic processGO:0009125560.013
neuron neuron synaptic transmissionGO:0007270600.013
nucleocytoplasmic transportGO:0006913480.013
axis specificationGO:000979840.013
Fly
cell cycle processGO:0022402570.013
positive regulation of cell communicationGO:00106472710.013
Rat
response to glucoseGO:00097491360.013
adenylate cyclase inhibiting opioid receptor signaling pathwayGO:003163520.013
negative regulation of rna biosynthetic processGO:19026791180.013
immune system processGO:00023762040.012
Fly
copulationGO:0007620170.012
regulation of protein kinase activityGO:00458591050.012
regulation of blood pressureGO:0008217830.012
regulation of ossificationGO:0030278320.012
regulation of growthGO:00400081050.012
cytoplasmic transportGO:00164821150.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
developmental process involved in reproductionGO:00030061590.012
Worm
negative regulation of cell proliferationGO:00082851190.012
lipid metabolic processGO:00066292830.012
pallium developmentGO:0021543420.012
negative regulation of protein metabolic processGO:00512481140.012
positive regulation of renin secretion into blood streamGO:190013510.012
negative regulation of catalytic activityGO:00430861030.012
positive regulation of neuron projection developmentGO:0010976990.012
negative regulation of transcription dna templatedGO:00458921160.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
negative regulation of growthGO:0045926370.012
regulation of phosphorylationGO:00423252480.012
embryo developmentGO:0009790490.012
Fly
detection of temperature stimulus involved in sensory perception of painGO:005096540.012
vasoconstrictionGO:0042310540.012
glucan metabolic processGO:0044042230.012
negative regulation of nucleobase containing compound metabolic processGO:00459341530.012
positive regulation of synaptic transmissionGO:0050806620.012
positive regulation of amine transportGO:0051954260.012
regulation of nucleoside metabolic processGO:0009118660.012
positive regulation of nucleotide catabolic processGO:0030813530.012
regulation of purine nucleotide metabolic processGO:19005421150.012
rho protein signal transductionGO:0007266110.012
positive regulation of response to stimulusGO:00485842850.012
involuntary skeletal muscle contractionGO:000301120.012
nucleotide catabolic processGO:00091661390.012
catabolic processGO:00090563510.011
response to retinoic acidGO:0032526630.011
positive regulation of the force of heart contraction by chemical signalGO:000309920.011
regulation of homotypic cell cell adhesionGO:003411040.011
response to other organismGO:00517072200.011
single organismal cell cell adhesionGO:0016337420.011
spinal cord developmentGO:0021510270.011
Mouse
response to dexamethasoneGO:0071548490.011
ribonucleoside monophosphate metabolic processGO:0009161880.011
cell projection morphogenesisGO:00488581230.011
Zebrafish Mouse Fly
chemosensory behaviorGO:000763520.011
regulation of kinase activityGO:00435491170.011
multi multicellular organism processGO:00447061380.011
positive regulation of the force of heart contraction by epinephrineGO:000305910.011
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.011
brain renin angiotensin systemGO:000203530.011
cellular catabolic processGO:00442482950.011
cell cycle checkpointGO:000007520.011
positive regulation of ion transportGO:0043270940.011
negative regulation of transportGO:00510511360.011
regulation of cellular catabolic processGO:00313291010.011
cellular ion homeostasisGO:00068731840.011
retinal ganglion cell axon guidanceGO:003129010.011
Mouse
camera type eye developmentGO:0043010480.011
intracellular transportGO:00469071850.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
aromatic compound catabolic processGO:00194391680.011
positive regulation of neuron differentiationGO:00456661260.011
olfactory behaviorGO:004204820.011
negative regulation of molecular functionGO:00440921330.011
Rat Fly
regulation of purine nucleotide catabolic processGO:0033121650.011
regulation of transporter activityGO:0032409500.011
circulatory system developmentGO:00723591340.011
Fly
negative regulation of gene expressionGO:00106291990.011
defense response to gram negative bacteriumGO:005082930.011
response to mechanical stimulusGO:00096121340.011
regulation of neuronal synaptic plasticityGO:0048168310.011
response to testosteroneGO:0033574550.010
blood circulationGO:00080151830.010
regulation of molecular functionGO:00650093980.010
Rat Fly
regulation of signal transductionGO:00099663180.010
Rat
sensory perception of mechanical stimulusGO:0050954170.010
sympathetic nervous system developmentGO:004848510.010
response to hypoxiaGO:00016662310.010
regulation of anatomical structure morphogenesisGO:00226031410.010
detection of temperature stimulusGO:001604840.010
regulation of vasodilationGO:0042312360.010
dendrite developmentGO:0016358720.010
Fly
vesicle mediated transportGO:00161921810.010
blood vessel developmentGO:0001568690.010

Isl2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.035
disease of anatomical entityDOID:700.035
central nervous system diseaseDOID:33100.012
brain diseaseDOID:93600.012