Rattus norvegicus

22 known processes

Pi4kb

phosphatidylinositol 4-kinase, catalytic, beta

(Aliases: Pik4cb)

Pi4kb biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron differentiationGO:00301823680.228
rna metabolic processGO:00160704060.178
regulation of rna biosynthetic processGO:20011413810.155
transcription dna templatedGO:00063513770.142
regulation of multicellular organismal developmentGO:20000263760.135
regulation of nucleic acid templated transcriptionGO:19035063800.135
rna biosynthetic processGO:00327743800.128
transcription from rna polymerase ii promoterGO:00063662520.124
positive regulation of macromolecule biosynthetic processGO:00105572470.104
single organism organelle organizationGO:19025891800.102
axon developmentGO:0061564960.101
cellular response to hormone stimulusGO:00328702470.098
nucleic acid templated transcriptionGO:00976593790.098
locomotionGO:00400112370.093
regulation of transcription dna templatedGO:00063553740.091
regulation of rna metabolic processGO:00512523910.088
macromolecule localizationGO:00330362520.088
macromolecular complex subunit organizationGO:00439333390.085
regulation of transcription from rna polymerase ii promoterGO:00063572340.084
positive regulation of nucleic acid templated transcriptionGO:19035081970.082
positive regulation of biosynthetic processGO:00098913190.078
regulation of cellular component organizationGO:00511283680.077
positive regulation of gene expressionGO:00106282440.076
neuron developmentGO:00486662860.076
negative regulation of cellular metabolic processGO:00313242810.076
negative regulation of metabolic processGO:00098923310.073
positive regulation of rna biosynthetic processGO:19026801970.071
reproductive processGO:00224143720.071
positive regulation of cellular biosynthetic processGO:00313282950.066
localization of cellGO:00516742020.065
positive regulation of nitrogen compound metabolic processGO:00511733340.064
positive regulation of rna metabolic processGO:00512542030.062
cellular response to endogenous stimulusGO:00714953770.061
regulation of anatomical structure morphogenesisGO:00226031410.060
cell projection organizationGO:00300303020.060
positive regulation of developmental processGO:00510942830.059
neuron projection developmentGO:00311752730.059
regulation of anatomical structure sizeGO:00900661350.057
cellular component morphogenesisGO:00329891550.056
positive regulation of transcription dna templatedGO:00458931970.055
regulation of nervous system developmentGO:00519602640.052
negative regulation of nucleic acid templated transcriptionGO:19035071170.052
organic acid metabolic processGO:00060822920.049
positive regulation of nucleobase containing compound metabolic processGO:00459353190.049
cellular component movementGO:00069282480.049
cellular component biogenesisGO:00440853680.048
anatomical structure morphogenesisGO:00096532980.048
intracellular signal transductionGO:00355563140.047
macromolecular complex assemblyGO:00650032730.044
regulation of cell differentiationGO:00455953200.044
organelle organizationGO:00069962660.044
multi organism reproductive processGO:00447032620.044
negative regulation of macromolecule metabolic processGO:00106052600.044
cellular amino acid metabolic processGO:00065201070.043
programmed cell deathGO:00125013920.042
protein transportGO:00150311320.042
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.041
protein phosphorylationGO:00064683450.041
response to other organismGO:00517072200.041
cell motilityGO:00488702020.039
response to nutrient levelsGO:00316673700.039
cell migrationGO:00164771970.039
single organism reproductive processGO:00447022970.038
regulation of protein phosphorylationGO:00019321830.038
cell projection morphogenesisGO:00488581230.038
neuron projection morphogenesisGO:00488121220.037
carboxylic acid metabolic processGO:00197522890.037
regulation of catalytic activityGO:00507903040.037
regulation of cell developmentGO:00602842630.037
cellular response to stressGO:00335542690.037
regulation of neuron differentiationGO:00456642080.036
cellular ketone metabolic processGO:0042180510.036
negative regulation of response to stimulusGO:00485851550.036
negative regulation of cellular component organizationGO:0051129830.036
oxoacid metabolic processGO:00434362900.036
amine metabolic processGO:0009308380.035
regulation of programmed cell deathGO:00430673410.035
membrane organizationGO:0061024940.034
cellular amine metabolic processGO:0044106380.034
positive regulation of programmed cell deathGO:00430681570.034
protein localizationGO:00081041910.034
reproductionGO:00000032450.034
carbohydrate derivative metabolic processGO:19011353460.034
central nervous system developmentGO:00074173110.034
multicellular organism reproductionGO:00325042330.033
cellular response to oxygen containing compoundGO:19017013860.032
growthGO:00400071650.032
cell morphogenesisGO:00009021420.032
regulation of neurogenesisGO:00507672470.032
response to extracellular stimulusGO:00099913800.032
nucleobase containing small molecule metabolic processGO:00550863160.032
secretionGO:00469033070.032
regulation of cellular amine metabolic processGO:003323880.031
cell morphogenesis involved in neuron differentiationGO:00486671060.031
heart morphogenesisGO:000300730.031
apoptotic processGO:00069153810.031
purine nucleotide metabolic processGO:00061632290.031
regulation of locomotionGO:00400121480.031
regulation of apoptotic processGO:00429813350.031
cellular response to organonitrogen compoundGO:00714171970.030
positive regulation of cell deathGO:00109421840.030
establishment of protein localizationGO:00451841410.030
cellular component assemblyGO:00226073600.030
regulation of growthGO:00400081050.029
multicellular organismal reproductive processGO:00486092330.029
regulation of cell proliferationGO:00421273590.029
developmental process involved in reproductionGO:00030061590.029
response to external biotic stimulusGO:00432072210.029
agingGO:00075682410.029
regulation of cell projection organizationGO:00313441750.028
negative regulation of rna biosynthetic processGO:19026791180.028
negative regulation of nitrogen compound metabolic processGO:00511721610.028
single organism biosynthetic processGO:00447113420.028
positive regulation of cell proliferationGO:00082842490.028
actin cytoskeleton organizationGO:0030036730.028
cytoskeleton organizationGO:00070101110.028
regulation of phosphorus metabolic processGO:00511743490.028
positive regulation of signalingGO:00230562700.027
tissue developmentGO:00098882520.027
regulation of secretion by cellGO:19035302080.027
response to monosaccharideGO:00342841590.027
intracellular transportGO:00469071850.027
response to decreased oxygen levelsGO:00362932370.027
positive regulation of cell differentiationGO:00455972170.027
regulation of cell morphogenesis involved in differentiationGO:0010769720.027
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.026
cellular response to lipidGO:00713962010.026
regulation of cellular ketone metabolic processGO:0010565270.026
ras protein signal transductionGO:0007265290.026
negative regulation of cellular biosynthetic processGO:00313271610.026
response to hypoxiaGO:00016662310.026
purine containing compound metabolic processGO:00725212530.025
positive regulation of cellular component organizationGO:00511302000.025
regulation of protein metabolic processGO:00512462890.025
regulation of cellular amino acid metabolic processGO:000652120.025
secretion by cellGO:00329402480.025
regulation of axonogenesisGO:0050770370.025
actin filament based processGO:0030029860.025
response to acid chemicalGO:00011012220.025
regulation of phosphorylationGO:00423252480.025
purine ribonucleotide metabolic processGO:00091502270.025
protein complex biogenesisGO:00702712630.024
regulation of cell migrationGO:00303341280.024
negative regulation of transcription dna templatedGO:00458921160.024
small gtpase mediated signal transductionGO:0007264360.024
positive regulation of multicellular organismal processGO:00512403870.024
developmental growthGO:00485891000.024
protein complex assemblyGO:00064612630.024
response to peptide hormoneGO:00434342780.024
response to hexoseGO:00097461440.024
cellular response to nitrogen compoundGO:19016992100.024
multi multicellular organism processGO:00447061380.023
response to purine containing compoundGO:00140741260.023
circadian rhythmGO:0007623880.023
regulation of protein modification processGO:00313991940.023
regulation of organelle organizationGO:0033043800.023
response to oxygen levelsGO:00704822650.022
negative regulation of gene expressionGO:00106291990.022
negative regulation of neurogenesisGO:0050768780.022
positive regulation of molecular functionGO:00440932300.022
catabolic processGO:00090563510.022
head developmentGO:00603222470.022
regulation of molecular functionGO:00650093980.022
negative regulation of multicellular organismal processGO:00512412030.022
heterocycle catabolic processGO:00467001670.022
cellular homeostasisGO:00197252520.022
regulation of cellular localizationGO:00603412630.021
organonitrogen compound biosynthetic processGO:19015661670.021
chemical homeostasisGO:00488782920.021
positive regulation of phosphate metabolic processGO:00459372620.021
homeostatic processGO:00425923310.021
purine nucleoside triphosphate metabolic processGO:00091441410.021
negative regulation of protein metabolic processGO:00512481140.021
negative regulation of cell developmentGO:0010721820.021
regulation of synaptic growth at neuromuscular junctionGO:000858210.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
response to growth factorGO:00708481890.021
response to inorganic substanceGO:00100353770.021
cellular lipid metabolic processGO:00442552080.021
response to glucoseGO:00097491360.021
response to bacteriumGO:00096172000.021
negative regulation of developmental processGO:00510931250.020
nucleobase containing compound catabolic processGO:00346551520.020
purine containing compound catabolic processGO:00725231380.020
protein complex subunit organizationGO:00718223020.020
cell growthGO:00160491040.020
single organism cellular localizationGO:19025801020.020
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.020
response to radiationGO:00093141370.020
positive regulation of phosphorylationGO:00423271770.020
positive regulation of phosphorus metabolic processGO:00105622620.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
cellular chemical homeostasisGO:00550822470.019
cellular catabolic processGO:00442482950.019
regulation of purine nucleotide metabolic processGO:19005421150.019
negative regulation of cell proliferationGO:00082851190.019
ribose phosphate metabolic processGO:00196932350.019
negative regulation of apoptotic processGO:00430661810.019
response to biotic stimulusGO:00096072260.019
cation transportGO:00068123820.019
positive regulation of apoptotic processGO:00430651540.019
positive regulation of catalytic activityGO:00430851840.019
regulation of intracellular signal transductionGO:19025312180.019
regulation of cell morphogenesisGO:0022604770.019
response to corticosteroidGO:00319602350.019
response to nutrientGO:00075842480.019
response to peptideGO:19016522920.019
cellular ion homeostasisGO:00068731840.019
positive regulation of cellular amino acid metabolic processGO:004576410.018
gliogenesisGO:0042063930.018
single organism catabolic processGO:00447122830.018
proteolysisGO:00065081750.018
anatomical structure formation involved in morphogenesisGO:0048646830.018
negative regulation of cell deathGO:00605482290.018
regulation of cellular protein metabolic processGO:00322682670.018
cellular macromolecule localizationGO:00707271220.018
cellular response to peptideGO:19016531330.018
vesicle mediated transportGO:00161921810.018
positive regulation of response to stimulusGO:00485842850.018
negative regulation of nervous system developmentGO:0051961790.018
regulation of neuron projection developmentGO:00109751610.018
positive regulation of transportGO:00510502450.018
regulation of cell growthGO:0001558850.018
positive regulation of protein phosphorylationGO:00019341350.018
cell type specific apoptotic processGO:00972851340.018
negative regulation of signalingGO:00230571570.017
synaptic growth at neuromuscular junctionGO:005112410.017
lipid metabolic processGO:00066292830.017
regulation of phosphate metabolic processGO:00192203490.017
regulation of signal transductionGO:00099663180.017
response to metal ionGO:00100382530.017
cardiac chamber developmentGO:000320510.017
cytokine productionGO:0001816610.017
circulatory system processGO:00030131830.017
response to carbohydrateGO:00097431830.017
negative regulation of rna metabolic processGO:00512531230.017
cellular response to growth factor stimulusGO:00713631620.017
positive regulation of protein modification processGO:00314011420.017
negative regulation of cell communicationGO:00106481580.017
organophosphate biosynthetic processGO:00904071430.017
regulation of establishment of protein localizationGO:0070201690.017
cell morphogenesis involved in differentiationGO:00009041190.017
cell part morphogenesisGO:00329901230.017
positive regulation of cellular amine metabolic processGO:003324030.017
protein oligomerizationGO:00512591910.016
chromatin organizationGO:0006325340.016
protein secretionGO:0009306340.016
axonogenesisGO:0007409710.016
biological adhesionGO:00226101100.016
negative regulation of programmed cell deathGO:00430691830.016
intracellular protein transportGO:0006886790.016
regulation of vesicle mediated transportGO:0060627810.016
purine nucleotide catabolic processGO:00061951360.016
regulation of secretionGO:00510462240.016
protein autophosphorylationGO:0046777660.016
rhythmic processGO:00485111560.016
nucleoside metabolic processGO:00091161790.016
response to woundingGO:00096112540.016
cytoskeleton dependent cytokinesisGO:006164020.016
positive regulation of cell developmentGO:00107201760.016
regulation of protein localizationGO:0032880810.016
chromatin modificationGO:0016568330.016
nucleotide catabolic processGO:00091661390.016
meiotic cell cycle processGO:190304630.016
response to ethanolGO:00454711620.016
single organism intracellular transportGO:19025821660.015
response to transition metal nanoparticleGO:19902671220.015
cation homeostasisGO:00550801950.015
cellular response to insulin stimulusGO:0032869810.015
sexual reproductionGO:00199531480.015
nucleoside phosphate metabolic processGO:00067532830.015
regulation of cellular component biogenesisGO:0044087860.015
cellular amide metabolic processGO:0043603440.015
regulation of catabolic processGO:00098941130.015
cell cycleGO:00070491010.015
ion homeostasisGO:00508012120.015
purine nucleoside metabolic processGO:00422781690.015
spindle organizationGO:000705120.015
cellular protein complex assemblyGO:0043623440.015
regulation of cell motilityGO:20001451310.015
synapse organizationGO:0050808460.015
positive regulation of nervous system developmentGO:00519621780.015
negative regulation of molecular functionGO:00440921330.014
peptidyl amino acid modificationGO:00181931260.014
muscle cell differentiationGO:0042692520.014
brain developmentGO:00074202470.014
regulation of hydrolase activityGO:00513361430.014
response to ketoneGO:19016541820.014
positive regulation of locomotionGO:00400171020.014
dendrite morphogenesisGO:0048813430.014
cytoplasmic transportGO:00164821150.014
regulation of neuron deathGO:19012141150.014
negative regulation of cell cycle phase transitionGO:190198840.014
single organism membrane organizationGO:0044802740.014
cellular response to peptide hormone stimulusGO:00713751200.014
circulatory system developmentGO:00723591340.014
organelle localizationGO:0051640550.014
gamete generationGO:00072761240.014
response to calcium ionGO:0051592590.014
response to oxidative stressGO:00069791860.013
organophosphate metabolic processGO:00196373700.013
regulation of hormone levelsGO:00108171870.013
response to glucocorticoidGO:00513842230.013
negative regulation of biosynthetic processGO:00098901680.013
cell cell signalingGO:00072673350.013
organic substance catabolic processGO:19015753160.013
dendrite developmentGO:0016358720.013
positive regulation of neuron differentiationGO:00456661260.013
synaptic transmissionGO:00072682350.013
purine nucleoside catabolic processGO:00061521240.013
immune system processGO:00023762040.013
regulation of protein transportGO:0051223680.013
development of primary sexual characteristicsGO:00451371070.013
nucleoside catabolic processGO:00091641260.013
response to retinoic acidGO:0032526630.013
behaviorGO:00076102050.013
regulation of actin cytoskeleton organizationGO:0032956300.013
circadian regulation of gene expressionGO:003292230.013
positive regulation of cell communicationGO:00106472710.013
nucleotide metabolic processGO:00091172790.013
cell adhesionGO:00071551100.013
carbohydrate derivative catabolic processGO:19011361470.013
regulation of kinase activityGO:00435491170.013
response to temperature stimulusGO:0009266940.013
negative regulation of signal transductionGO:0009968830.013
transmembrane transportGO:00550854120.013
response to estrogenGO:00436272320.013
response to alkaloidGO:00432791320.012
positive regulation of cellular protein metabolic processGO:00322701670.012
nucleoside triphosphate catabolic processGO:00091431230.012
positive regulation of secretionGO:00510471400.012
spermatogenesisGO:0007283990.012
negative regulation of neuron deathGO:1901215690.012
lipid storageGO:001991510.012
response to cytokineGO:00340972150.012
purine ribonucleoside metabolic processGO:00461281680.012
ion transmembrane transportGO:00342203650.012
positive regulation of neurogenesisGO:00507691650.012
neuron apoptotic processGO:0051402880.012
negative regulation of neuron differentiationGO:0045665620.012
oxidation reduction processGO:00551143040.012
alcohol metabolic processGO:0006066770.012
muscle system processGO:00030121150.012
multicellular organism growthGO:003526410.012
negative regulation of innate immune responseGO:004582440.012
endomembrane system organizationGO:0010256480.012
gastrulationGO:000736920.012
regulation of membrane potentialGO:00423911100.012
response to campGO:0051591910.012
organ morphogenesisGO:0009887750.012
regulation of stem cell differentiationGO:200073620.012
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.012
regulation of protein serine threonine kinase activityGO:0071900640.012
positive regulation of protein transportGO:0051222410.012
tube formationGO:003514830.012
male gamete generationGO:0048232990.012
embryonic pattern specificationGO:000988010.012
eye morphogenesisGO:004859240.012
regulation of cellular component sizeGO:0032535510.012
adult locomotory behaviorGO:000834440.012
cellular metal ion homeostasisGO:00068751720.012
cell cell signaling involved in cell fate commitmentGO:004516820.012
nitrogen compound transportGO:00717052290.012
cellular response to abiotic stimulusGO:0071214850.011
learning or memoryGO:0007611900.011
heart developmentGO:0007507720.011
regulation of nucleotide metabolic processGO:00061401170.011
rho protein signal transductionGO:0007266110.011
motor neuron axon guidanceGO:000804510.011
small molecule biosynthetic processGO:00442831240.011
regulation of cytoskeleton organizationGO:0051493490.011
lipid localizationGO:0010876620.011
defense response to gram negative bacteriumGO:005082930.011
neuron neuron synaptic transmissionGO:0007270600.011
positive regulation of immune system processGO:0002684900.011
anion transportGO:00068201780.011
response to insulinGO:00328681330.011
maintenance of locationGO:0051235170.011
cell cycle checkpointGO:000007520.011
purine ribonucleoside triphosphate metabolic processGO:00092051400.011
protein homooligomerizationGO:0051260910.011
organic cyclic compound catabolic processGO:19013611750.011
regulation of protein kinase activityGO:00458591050.011
negative regulation of cellular protein metabolic processGO:00322691060.011
negative regulation of transportGO:00510511360.011
female pregnancyGO:00075651220.011
sensory organ developmentGO:0007423740.011
glycosyl compound catabolic processGO:19016581260.011
positive regulation of transferase activityGO:0051347810.011
peptide metabolic processGO:0006518320.011
organic hydroxy compound metabolic processGO:19016151150.011
defense responseGO:00069521940.011
actin filament organizationGO:0007015420.011
ribonucleotide metabolic processGO:00092592310.011
axis specificationGO:000979840.011
positive regulation of protein metabolic processGO:00512471780.010
dephosphorylationGO:0016311980.010
regulation of cellular component movementGO:00512701500.010
regulation of immune system processGO:00026821230.010
regulation of cytokine productionGO:0001817560.010
cellular nitrogen compound catabolic processGO:00442701630.010
negative regulation of mitotic cell cycle phase transitionGO:190199130.010
bmp signaling pathwayGO:003050940.010
positive regulation of endothelial cell migrationGO:001059540.010
chemotaxisGO:0006935660.010
blood circulationGO:00080151830.010
organophosphate catabolic processGO:00464341480.010
somatic stem cell divisionGO:004810320.010
metal ion transportGO:00300012890.010
peptidyl tyrosine phosphorylationGO:0018108720.010
cellular cation homeostasisGO:00300031800.010
cytokine biosynthetic processGO:004208930.010
g protein coupled receptor signaling pathwayGO:00071862420.010
negative regulation of phosphorus metabolic processGO:0010563800.010
aminoglycan biosynthetic processGO:000602340.010
positive regulation of cell migrationGO:0030335960.010

Pi4kb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.063
nervous system diseaseDOID:86300.063
musculoskeletal system diseaseDOID:1700.032
connective tissue diseaseDOID:6500.016
sensory system diseaseDOID:005015500.013
central nervous system diseaseDOID:33100.012
brain diseaseDOID:93600.011
epilepsy syndromeDOID:182600.011