Rattus norvegicus

139 known processes

Spp1

secreted phosphoprotein 1

(Aliases: OSP)

Spp1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nutrientGO:00075842480.337
response to woundingGO:00096112540.308
cell motilityGO:00488702020.268
cation transportGO:00068123820.210
regulation of cellular component movementGO:00512701500.175
response to external biotic stimulusGO:00432072210.172
response to extracellular stimulusGO:00099913800.169
cellular response to endogenous stimulusGO:00714953770.168
cellular component movementGO:00069282480.163
cellular component assemblyGO:00226073600.163
vesicle mediated transportGO:00161921810.154
regulation of cell motilityGO:20001451310.153
negative regulation of response to stimulusGO:00485851550.151
regulation of locomotionGO:00400121480.148
protein complex subunit organizationGO:00718223020.146
chemical homeostasisGO:00488782920.144
programmed cell deathGO:00125013920.142
wound healingGO:00420601220.142
regulation of programmed cell deathGO:00430673410.142
cell cell signalingGO:00072673350.140
carboxylic acid biosynthetic processGO:0046394830.135
locomotionGO:00400112370.134
positive regulation of cell migrationGO:0030335960.131
cell migrationGO:00164771970.130
macromolecular complex subunit organizationGO:00439333390.127
anatomical structure morphogenesisGO:00096532980.126
organic acid metabolic processGO:00060822920.125
defense responseGO:00069521940.125
cellular lipid metabolic processGO:00442552080.120
response to vitaminGO:00332731310.119
response to estrogenGO:00436272320.115
regulation of cellular component organizationGO:00511283680.114
cellular response to stressGO:00335542690.112
transmembrane transportGO:00550854120.111
neuron differentiationGO:00301823680.109
protein complex assemblyGO:00064612630.107
cellular response to organic cyclic compoundGO:00714072020.106
positive regulation of cell motilityGO:2000147970.105
regulation of apoptotic processGO:00429813350.104
cellular component biogenesisGO:00440853680.101
response to other organismGO:00517072200.101
response to mechanical stimulusGO:00096121340.100
response to molecule of bacterial originGO:00022371940.100
metal ion transportGO:00300012890.099
apoptotic processGO:00069153810.097
tissue regenerationGO:0042246360.096
lipid metabolic processGO:00066292830.095
positive regulation of cell communicationGO:00106472710.095
tissue developmentGO:00098882520.095
regulation of cell migrationGO:00303341280.091
localization of cellGO:00516742020.089
agingGO:00075682410.086
developmental growthGO:00485891000.086
cellular response to oxygen containing compoundGO:19017013860.086
central nervous system developmentGO:00074173110.084
response to bacteriumGO:00096172000.084
reproductive processGO:00224143720.084
regulation of cell developmentGO:00602842630.083
cell projection organizationGO:00300303020.082
positive regulation of transportGO:00510502450.082
ion transmembrane transportGO:00342203650.082
positive regulation of multicellular organismal processGO:00512403870.081
response to nutrient levelsGO:00316673700.079
cellular response to nitrogen compoundGO:19016992100.078
regulation of nervous system developmentGO:00519602640.077
protein complex biogenesisGO:00702712630.076
cellular cation homeostasisGO:00300031800.076
response to ethanolGO:00454711620.076
regulation of ion transportGO:00432692450.076
response to inorganic substanceGO:00100353770.076
regulation of metal ion transportGO:00109591180.075
cellular metal ion homeostasisGO:00068751720.074
growthGO:00400071650.074
positive regulation of response to stimulusGO:00485842850.073
response to metal ionGO:00100382530.073
regulation of molecular functionGO:00650093980.072
negative regulation of cellular biosynthetic processGO:00313271610.071
regulation of response to external stimulusGO:00321011060.071
response to corticosteroidGO:00319602350.071
positive regulation of nitrogen compound metabolic processGO:00511733340.069
response to growth factorGO:00708481890.067
response to glucocorticoidGO:00513842230.066
oxoacid metabolic processGO:00434362900.066
carboxylic acid metabolic processGO:00197522890.065
positive regulation of ion transportGO:0043270940.064
response to lipopolysaccharideGO:00324961910.064
response to tumor necrosis factorGO:0034612560.063
multicellular organismal reproductive processGO:00486092330.062
single organism biosynthetic processGO:00447113420.061
cellular ion homeostasisGO:00068731840.061
positive regulation of nucleobase containing compound metabolic processGO:00459353190.060
cellular response to lipidGO:00713962010.060
macromolecular complex assemblyGO:00650032730.059
cellular homeostasisGO:00197252520.058
homeostatic processGO:00425923310.058
single organism catabolic processGO:00447122830.058
regulation of cell proliferationGO:00421273590.057
single organism organelle organizationGO:19025891800.057
negative regulation of cell deathGO:00605482290.057
multicellular organism reproductionGO:00325042330.057
regulation of neurogenesisGO:00507672470.056
response to axon injuryGO:0048678590.056
calcium ion transportGO:00068161310.056
positive regulation of cellular component organizationGO:00511302000.056
developmental process involved in reproductionGO:00030061590.055
positive regulation of nervous system developmentGO:00519621780.054
regulation of cellular localizationGO:00603412630.054
fatty acid metabolic processGO:0006631990.054
regulation of phosphate metabolic processGO:00192203490.053
protein oligomerizationGO:00512591910.053
neuron projection developmentGO:00311752730.051
single organism reproductive processGO:00447022970.050
cellular component morphogenesisGO:00329891550.050
behaviorGO:00076102050.050
gastrulationGO:000736920.050
small molecule biosynthetic processGO:00442831240.049
organic acid biosynthetic processGO:0016053830.049
response to oxidative stressGO:00069791860.049
intracellular signal transductionGO:00355563140.049
organelle organizationGO:00069962660.049
inflammatory responseGO:00069541500.048
negative regulation of metabolic processGO:00098923310.047
anion transportGO:00068201780.047
single organism intracellular transportGO:19025821660.046
cellular response to growth factor stimulusGO:00713631620.046
positive regulation of cell developmentGO:00107201760.045
cellular response to tumor necrosis factorGO:0071356460.044
response to peptideGO:19016522920.043
regulation of cell differentiationGO:00455953200.043
regenerationGO:00310991630.043
synaptic transmissionGO:00072682350.043
positive regulation of locomotionGO:00400171020.042
secretion by cellGO:00329402480.042
reproductionGO:00000032450.042
positive regulation of signalingGO:00230562700.042
calcium ion homeostasisGO:00550741620.042
monocarboxylic acid metabolic processGO:00327871520.042
positive regulation of cytosolic calcium ion concentrationGO:00072041220.042
neuron developmentGO:00486662860.041
lipid biosynthetic processGO:00086101280.040
regulation of neuron differentiationGO:00456642080.040
cell part morphogenesisGO:00329901230.039
positive regulation of programmed cell deathGO:00430681570.039
response to biotic stimulusGO:00096072260.038
positive regulation of cellular biosynthetic processGO:00313282950.038
positive regulation of phosphorus metabolic processGO:00105622620.038
response to estradiolGO:00323551640.038
endocytosisGO:0006897840.038
divalent inorganic cation homeostasisGO:00725071650.038
cellular response to hormone stimulusGO:00328702470.038
carbohydrate derivative metabolic processGO:19011353460.038
positive regulation of cell proliferationGO:00082842490.038
positive regulation of phosphate metabolic processGO:00459372620.037
proteolysisGO:00065081750.037
cellular response to corticosteroid stimulusGO:0071384690.037
cellular response to extracellular stimulusGO:0031668730.037
positive regulation of apoptotic processGO:00430651540.037
neuron deathGO:00709971270.036
positive regulation of neurogenesisGO:00507691650.036
nucleic acid templated transcriptionGO:00976593790.036
regulation of blood circulationGO:19035221100.035
rna biosynthetic processGO:00327743800.035
response to purine containing compoundGO:00140741260.035
regulation of rna metabolic processGO:00512523910.034
catabolic processGO:00090563510.034
regulation of system processGO:00440572080.034
positive regulation of calcium ion transportGO:0051928360.034
positive regulation of biosynthetic processGO:00098913190.034
hormone secretionGO:00468791150.034
actin filament based processGO:0030029860.034
rna metabolic processGO:00160704060.034
neuron projection morphogenesisGO:00488121220.033
secretionGO:00469033070.033
nitrogen compound transportGO:00717052290.033
regulation of signal transductionGO:00099663180.033
response to transition metal nanoparticleGO:19902671220.033
response to organophosphorusGO:00466831020.033
regulation of protein metabolic processGO:00512462890.033
regulation of cellular protein metabolic processGO:00322682670.032
transcription dna templatedGO:00063513770.032
regulation of vesicle mediated transportGO:0060627810.032
positive regulation of gene expressionGO:00106282440.032
epithelium developmentGO:0060429960.032
response to peptide hormoneGO:00434342780.032
regulation of hormone levelsGO:00108171870.032
positive regulation of cell differentiationGO:00455972170.032
reproductive system developmentGO:00614581280.032
signal releaseGO:00230611450.031
response to reactive oxygen speciesGO:00003021200.031
response to antidepressantGO:003627640.031
regulation of cellular ketone metabolic processGO:0010565270.031
blood circulationGO:00080151830.031
cytosolic calcium ion homeostasisGO:00514801400.031
nucleobase containing small molecule metabolic processGO:00550863160.031
regulation of response to woundingGO:1903034690.031
neurological system processGO:00508772190.030
cellular amine metabolic processGO:0044106380.030
alcohol metabolic processGO:0006066770.030
positive regulation of neuron differentiationGO:00456661260.030
positive regulation of cell projection organizationGO:00313461110.030
positive regulation of synaptic transmissionGO:0050806620.030
regulation of defense responseGO:0031347680.029
positive regulation of molecular functionGO:00440932300.029
rhythmic processGO:00485111560.029
regulation of cellular extravasationGO:000269120.029
divalent inorganic cation transportGO:00725111340.028
protein phosphorylationGO:00064683450.028
regulation of nucleic acid templated transcriptionGO:19035063800.028
maternal process involved in female pregnancyGO:0060135380.028
cellular response to external stimulusGO:00714961180.027
regulation of synaptic transmissionGO:00508041410.027
cellular chemical homeostasisGO:00550822470.027
multi organism reproductive processGO:00447032620.027
organonitrogen compound biosynthetic processGO:19015661670.027
multi multicellular organism processGO:00447061380.027
regulation of calcium ion transportGO:0051924770.027
axonogenesisGO:0007409710.027
regulation of phosphorylationGO:00423252480.026
cellular response to glucocorticoid stimulusGO:0071385680.026
response to ketoneGO:19016541820.026
regulation of catalytic activityGO:00507903040.026
negative regulation of transcription dna templatedGO:00458921160.026
purine containing compound metabolic processGO:00725212530.026
regulation of response to stressGO:00801341260.026
macromolecule localizationGO:00330362520.026
cell chemotaxisGO:0060326310.026
cellular response to steroid hormone stimulusGO:0071383930.026
regulation of cellular amino acid metabolic processGO:000652120.026
positive regulation of phosphorylationGO:00423271770.025
muscle system processGO:00030121150.025
cellular response to ketoneGO:1901655510.025
negative regulation of innate immune responseGO:004582440.025
regulation of neuron deathGO:19012141150.025
response to cytokineGO:00340972150.025
organic substance catabolic processGO:19015753160.025
response to oxygen levelsGO:00704822650.025
macrophage chemotaxisGO:004824620.025
regulation of rna biosynthetic processGO:20011413810.025
positive regulation of neuron projection developmentGO:0010976990.025
immune system processGO:00023762040.024
regulation of transmembrane transportGO:00347621220.024
negative regulation of programmed cell deathGO:00430691830.024
cellular response to oxidative stressGO:0034599760.024
organophosphate metabolic processGO:00196373700.024
intracellular transportGO:00469071850.024
biological adhesionGO:00226101100.024
organonitrogen compound catabolic processGO:19015651790.024
female pregnancyGO:00075651220.024
response to carbohydrateGO:00097431830.023
cellular ketone metabolic processGO:0042180510.023
cellular calcium ion homeostasisGO:00068741600.023
protein homooligomerizationGO:0051260910.023
positive regulation of signal transductionGO:00099671750.023
response to hydrogen peroxideGO:0042542890.023
regulation of transcription dna templatedGO:00063553740.023
positive regulation of response to external stimulusGO:0032103510.023
positive regulation of cell deathGO:00109421840.023
divalent metal ion transportGO:00708381320.022
response to zinc ionGO:0010043390.022
negative regulation of cell communicationGO:00106481580.022
positive regulation of macromolecule biosynthetic processGO:00105572470.022
response to hexoseGO:00097461440.022
cellular response to molecule of bacterial originGO:0071219560.022
leukocyte chemotaxisGO:0030595220.022
negative regulation of apoptotic processGO:00430661810.022
regulation of immune system processGO:00026821230.022
response to campGO:0051591910.022
response to glucoseGO:00097491360.022
cytoplasmic transportGO:00164821150.022
positive regulation of developmental processGO:00510942830.021
metal ion homeostasisGO:00550651860.021
limb morphogenesisGO:003510840.021
regulation of secretion by cellGO:19035302080.021
ras protein signal transductionGO:0007265290.021
response to toxic substanceGO:00096361330.021
regulation of ion transmembrane transportGO:00347651210.021
gliogenesisGO:0042063930.021
cell morphogenesis involved in neuron differentiationGO:00486671060.021
cellular divalent inorganic cation homeostasisGO:00725031620.021
regulation of cell projection organizationGO:00313441750.020
response to radiationGO:00093141370.020
negative regulation of nitrogen compound metabolic processGO:00511721610.020
amide transportGO:00428861050.020
positive regulation of secretionGO:00510471400.020
negative regulation of signalingGO:00230571570.020
organic hydroxy compound metabolic processGO:19016151150.020
positive regulation of catalytic activityGO:00430851840.020
positive regulation of voltage gated calcium channel activityGO:190138710.020
regulation of purine nucleotide metabolic processGO:19005421150.019
regulation of cell adhesionGO:0030155520.019
regulation of cellular component biogenesisGO:0044087860.019
response to vitamin dGO:0033280340.019
brain developmentGO:00074202470.019
ion homeostasisGO:00508012120.019
epithelial cell proliferationGO:0050673540.019
positive regulation of protein phosphorylationGO:00019341350.019
regulation of neuron projection developmentGO:00109751610.019
nucleoside triphosphate metabolic processGO:00091411440.019
negative regulation of rna biosynthetic processGO:19026791180.019
cellular response to organonitrogen compoundGO:00714171970.019
epithelial cell differentiationGO:0030855710.019
transcription from rna polymerase ii promoterGO:00063662520.019
negative regulation of biosynthetic processGO:00098901680.019
positive regulation of protein metabolic processGO:00512471780.019
regulation of homeostatic processGO:00328441010.018
inorganic cation transmembrane transportGO:00986622020.018
reproductive structure developmentGO:00486081280.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
innate immune responseGO:0045087350.018
cellular catabolic processGO:00442482950.018
cellular response to peptideGO:19016531330.018
regulation of cellular amine metabolic processGO:003323880.018
protein maturationGO:0051604680.018
purine ribonucleotide metabolic processGO:00091502270.018
cellular response to alcoholGO:0097306870.018
negative regulation of gene expressionGO:00106291990.018
circulatory system processGO:00030131830.018
regulation of skeletal muscle cell differentiationGO:200101410.018
ribose phosphate metabolic processGO:00196932350.017
positive regulation of transcription dna templatedGO:00458931970.017
cell adhesionGO:00071551100.017
regulation of camp metabolic processGO:0030814430.017
protein transportGO:00150311320.017
negative regulation of macromolecule biosynthetic processGO:00105581480.017
organophosphate biosynthetic processGO:00904071430.017
dna metabolic processGO:0006259960.017
regulation of inflammatory responseGO:0050727480.017
head developmentGO:00603222470.017
regulation of anatomical structure morphogenesisGO:00226031410.017
cell type specific apoptotic processGO:00972851340.017
negative regulation of developmental processGO:00510931250.017
negative regulation of neuron differentiationGO:0045665620.017
negative regulation of catalytic activityGO:00430861030.017
regulation of membrane potentialGO:00423911100.017
response to high density lipoprotein particleGO:005509920.017
sexual reproductionGO:00199531480.017
skeletal muscle tissue regenerationGO:0043403100.017
regulation of anatomical structure sizeGO:00900661350.017
reactive oxygen species metabolic processGO:0072593370.017
cellular response to nutrient levelsGO:0031669600.017
positive regulation of secretion by cellGO:19035321280.016
g protein coupled receptor signaling pathwayGO:00071862420.016
purine nucleotide metabolic processGO:00061632290.016
negative regulation of extrinsic apoptotic signaling pathwayGO:200123740.016
lipid transportGO:0006869610.016
regulation of hydrolase activityGO:00513361430.016
cell morphogenesis involved in differentiationGO:00009041190.016
cation homeostasisGO:00550801950.016
regulation of blood pressureGO:0008217830.016
regulation of cytokine productionGO:0001817560.016
unsaturated fatty acid biosynthetic processGO:0006636210.016
regulation of lymphocyte migrationGO:200040110.016
positive regulation of cellular protein metabolic processGO:00322701670.016
regulation of cell morphogenesisGO:0022604770.016
negative regulation of macromolecule metabolic processGO:00106052600.016
small gtpase mediated signal transductionGO:0007264360.016
actin cytoskeleton organizationGO:0030036730.016
cell morphogenesisGO:00009021420.016
regulation of endocytosisGO:0030100420.016
receptor mediated endocytosisGO:0006898420.016
hormone transportGO:00099141210.016
protein heterooligomerizationGO:0051291890.015
positive regulation of hormone secretionGO:0046887650.015
organic anion transportGO:00157111320.015
axon developmentGO:0061564960.015
carbohydrate derivative catabolic processGO:19011361470.015
response to monosaccharideGO:00342841590.015
negative regulation of cellular metabolic processGO:00313242810.015
regulation of catabolic processGO:00098941130.015
interleukin 1 productionGO:0032612110.015
phospholipid metabolic processGO:0006644610.015
reactive oxygen species biosynthetic processGO:190340980.015
amine metabolic processGO:0009308380.015
acute inflammatory responseGO:0002526580.015
negative regulation of rna metabolic processGO:00512531230.015
eosinophil chemotaxisGO:004824530.015
monovalent inorganic cation transportGO:00156721720.015
glycerolipid metabolic processGO:0046486670.015
positive regulation of cellular component biogenesisGO:0044089550.015
regulation of ion homeostasisGO:2000021630.015
ribonucleotide metabolic processGO:00092592310.015
negative regulation of protein metabolic processGO:00512481140.014
protein localizationGO:00081041910.014
regulation of neuron apoptotic processGO:0043523830.014
nucleoside phosphate metabolic processGO:00067532830.014
negative regulation of neurogenesisGO:0050768780.014
negative regulation of neuron apoptotic processGO:0043524450.014
regulation of cellular catabolic processGO:00313291010.014
regulation of reactive oxygen species metabolic processGO:2000377260.014
cellular response to interleukin 1GO:0071347370.014
regulation of small gtpase mediated signal transductionGO:0051056480.014
defense response to gram negative bacteriumGO:005082930.014
positive regulation of intracellular signal transductionGO:19025331380.014
peptidyl amino acid modificationGO:00181931260.014
muscle structure developmentGO:0061061870.014
dephosphorylationGO:0016311980.014
regulation of cell activationGO:0050865500.014
response to indole 3 methanolGO:007168020.014
action potentialGO:0001508540.014
positive regulation of lymphocyte migrationGO:200040310.014
response to fibroblast growth factorGO:0071774290.014
negative regulation of transportGO:00510511360.014
muscle contractionGO:0006936880.014
reactive nitrogen species metabolic processGO:200105710.014
sequestering of calcium ionGO:005120880.014
cellular response to peptide hormone stimulusGO:00713751200.014
negative regulation of neuron deathGO:1901215690.014
lymphocyte migrationGO:007267630.013
negative regulation of cellular component organizationGO:0051129830.013
regulation of t cell migrationGO:200040410.013
regulation of protein phosphorylationGO:00019321830.013
positive regulation of rna biosynthetic processGO:19026801970.013
cellular response to reactive oxygen speciesGO:0034614550.013
positive regulation of nucleotide metabolic processGO:0045981910.013
nucleotide metabolic processGO:00091172790.013
response to fatty acidGO:0070542650.013
smooth muscle cell migrationGO:0014909360.013
mononuclear cell migrationGO:007167430.013
regulation of secretionGO:00510462240.013
positive regulation of cellular amine metabolic processGO:003324030.013
icosanoid metabolic processGO:0006690380.013
cellular response to low density lipoprotein particle stimulusGO:007140430.013
response to electrical stimulusGO:0051602560.013
cellular amino acid metabolic processGO:00065201070.013
formation of primary germ layerGO:000170410.013
positive regulation of protein modification processGO:00314011420.013
negative regulation of molecular functionGO:00440921330.013
purine containing compound biosynthetic processGO:0072522850.013
negative regulation of multicellular organismal processGO:00512412030.013
cellular response to cytokine stimulusGO:00713451270.013
striated muscle tissue developmentGO:0014706580.012
sensory perceptionGO:00076001010.012
response to amino acidGO:0043200750.012
response to activityGO:0014823730.012
response to alkaloidGO:00432791320.012
immune responseGO:00069551040.012
purine nucleotide biosynthetic processGO:0006164830.012
actin filament organizationGO:0007015420.012
positive regulation of hydrolase activityGO:0051345860.012
multicellular organismal signalingGO:0035637440.012
positive regulation of cellular component movementGO:00512721020.012
apoptotic signaling pathwayGO:0097190270.012
regulation of monocyte chemotaxisGO:009002530.012
glial cell differentiationGO:0010001650.012
gamete generationGO:00072761240.012
cell projection morphogenesisGO:00488581230.012
regulation of phosphorus metabolic processGO:00511743490.012
regulation of peptidase activityGO:0052547550.012
negative regulation of nucleic acid templated transcriptionGO:19035071170.012
positive regulation of behaviorGO:0048520380.012
nucleotide biosynthetic processGO:0009165980.012
endomembrane system organizationGO:0010256480.012
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.012
transmission of nerve impulseGO:0019226420.012
regulation of protein modification processGO:00313991940.012
positive regulation of homeostatic processGO:0032846490.012
purine ribonucleotide catabolic processGO:00091541360.012
membrane organizationGO:0061024940.012
ribonucleotide biosynthetic processGO:0009260850.012
organic cyclic compound catabolic processGO:19013611750.012
chemotaxisGO:0006935660.011
cellular response to acid chemicalGO:0071229750.011
insulin secretionGO:0030073690.011
sex differentiationGO:00075481130.011
positive regulation of rna metabolic processGO:00512542030.011
carbohydrate homeostasisGO:0033500750.011
anion transmembrane transportGO:0098656770.011
cellular response to drugGO:0035690300.011
protein processingGO:0016485680.011
development of primary sexual characteristicsGO:00451371070.011
regulation of body fluid levelsGO:0050878900.011
leukocyte activationGO:0045321760.011
regulation of blood vessel sizeGO:0050880890.011
skeletal muscle cell differentiationGO:003591420.011
astrocyte differentiationGO:0048708190.011
regulation of transcription from rna polymerase ii promoterGO:00063572340.011
axis specificationGO:000979840.011
actin filament bundle assemblyGO:0051017190.011
positive regulation of defense responseGO:0031349370.011
response to vitamin kGO:003257140.011
negative regulation of response to tumor cellGO:000283520.011
sequestering of metal ionGO:005123890.011
cellular macromolecule localizationGO:00707271220.011
positive regulation of reactive oxygen species metabolic processGO:2000379160.011
neuronal action potentialGO:0019228350.011
response to ionizing radiationGO:0010212590.011
response to dexamethasoneGO:0071548490.011
negative regulation of homeostatic processGO:0032845470.011
response to transforming growth factor betaGO:0071559460.011
positive regulation of cytokine productionGO:0001819420.011
cellular response to metal ionGO:0071248550.011
inorganic ion transmembrane transportGO:00986602290.011

Spp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.028
disease of anatomical entityDOID:700.028
musculoskeletal system diseaseDOID:1700.015
sensory system diseaseDOID:005015500.012