Rattus norvegicus

6 known processes

Tub

tubby homolog (mouse)

Tub biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inorganic ion transmembrane transportGO:00986602290.237
monovalent inorganic cation transportGO:00156721720.173
ribonucleotide metabolic processGO:00092592310.165
purine nucleotide metabolic processGO:00061632290.161
macromolecular complex subunit organizationGO:00439333390.145
positive regulation of phosphate metabolic processGO:00459372620.144
anion transportGO:00068201780.143
regulation of ion transportGO:00432692450.139
organic substance catabolic processGO:19015753160.127
lipid biosynthetic processGO:00086101280.106
positive regulation of signal transductionGO:00099671750.105
organonitrogen compound biosynthetic processGO:19015661670.104
vesicle mediated transportGO:00161921810.104
regulation of molecular functionGO:00650093980.101
organophosphate metabolic processGO:00196373700.100
regulation of phosphate metabolic processGO:00192203490.100
intracellular signal transductionGO:00355563140.096
sodium ion transmembrane transportGO:0035725670.091
transmembrane transportGO:00550854120.090
cellular component assemblyGO:00226073600.087
ion transmembrane transportGO:00342203650.087
regulation of catalytic activityGO:00507903040.086
head developmentGO:00603222470.085
positive regulation of signalingGO:00230562700.085
response to lipopolysaccharideGO:00324961910.084
carboxylic acid metabolic processGO:00197522890.083
nucleotide metabolic processGO:00091172790.082
regulation of phosphorus metabolic processGO:00511743490.081
cell projection organizationGO:00300303020.079
organic hydroxy compound metabolic processGO:19016151150.078
carbohydrate derivative metabolic processGO:19011353460.077
lipid metabolic processGO:00066292830.074
cell motilityGO:00488702020.072
purine containing compound metabolic processGO:00725212530.070
regulation of neurogenesisGO:00507672470.069
response to nutrient levelsGO:00316673700.068
nucleoside phosphate metabolic processGO:00067532830.068
nucleobase containing small molecule metabolic processGO:00550863160.068
ribonucleoside triphosphate catabolic processGO:00092031220.068
positive regulation of cell communicationGO:00106472710.068
positive regulation of multicellular organismal processGO:00512403870.066
single organism biosynthetic processGO:00447113420.065
reproductive processGO:00224143720.065
nucleotide biosynthetic processGO:0009165980.064
regulation of membrane potentialGO:00423911100.062
sodium ion transportGO:0006814820.061
peptide secretionGO:0002790860.061
protein complex biogenesisGO:00702712630.061
cell morphogenesisGO:00009021420.060
regulation of cellular localizationGO:00603412630.060
positive regulation of cell differentiationGO:00455972170.059
protein complex assemblyGO:00064612630.059
cation transportGO:00068123820.057
positive regulation of molecular functionGO:00440932300.056
regulation of secretionGO:00510462240.055
inorganic cation transmembrane transportGO:00986622020.054
cellular component movementGO:00069282480.054
ribose phosphate metabolic processGO:00196932350.054
positive regulation of phosphorus metabolic processGO:00105622620.053
protein phosphorylationGO:00064683450.053
response to molecule of bacterial originGO:00022371940.052
organelle organizationGO:00069962660.052
cellular response to oxygen containing compoundGO:19017013860.051
purine ribonucleoside metabolic processGO:00461281680.050
neuron differentiationGO:00301823680.050
cellular metal ion homeostasisGO:00068751720.050
purine ribonucleotide metabolic processGO:00091502270.049
organophosphate biosynthetic processGO:00904071430.048
positive regulation of response to stimulusGO:00485842850.046
response to growth factorGO:00708481890.046
monocarboxylic acid metabolic processGO:00327871520.045
regulation of peptide hormone secretionGO:0090276800.045
brain developmentGO:00074202470.044
cellular amino acid metabolic processGO:00065201070.044
oxoacid metabolic processGO:00434362900.044
ribonucleoside triphosphate metabolic processGO:00091991410.044
ribonucleotide biosynthetic processGO:0009260850.043
multicellular organism reproductionGO:00325042330.043
nucleoside phosphate biosynthetic processGO:19012931020.043
single organism catabolic processGO:00447122830.043
regulation of cellular component organizationGO:00511283680.043
taxisGO:0042330670.042
regulation of cyclic nucleotide metabolic processGO:0030799510.041
negative regulation of multicellular organismal processGO:00512412030.040
negative regulation of cell communicationGO:00106481580.039
response to bacteriumGO:00096172000.039
purine nucleotide biosynthetic processGO:0006164830.039
cyclic nucleotide metabolic processGO:0009187800.038
purine ribonucleotide biosynthetic processGO:0009152810.038
response to inorganic substanceGO:00100353770.038
monocarboxylic acid transportGO:0015718520.038
positive regulation of nucleotide metabolic processGO:0045981910.038
purine nucleoside metabolic processGO:00422781690.038
cellular amine metabolic processGO:0044106380.038
regulation of intracellular signal transductionGO:19025312180.037
response to other organismGO:00517072200.037
ribose phosphate biosynthetic processGO:0046390870.037
calcium ion transmembrane transportGO:0070588700.037
cellular component biogenesisGO:00440853680.037
cellular component morphogenesisGO:00329891550.036
protein oligomerizationGO:00512591910.036
regulation of transferase activityGO:00513381230.036
response to biotic stimulusGO:00096072260.035
response to ketoneGO:19016541820.035
regulation of muscle tissue developmentGO:1901861250.035
nucleoside triphosphate metabolic processGO:00091411440.034
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.034
cell part morphogenesisGO:00329901230.034
regulation of rna biosynthetic processGO:20011413810.034
nucleoside catabolic processGO:00091641260.033
secretion by cellGO:00329402480.033
neurological system processGO:00508772190.033
single organism cellular localizationGO:19025801020.033
purine ribonucleotide catabolic processGO:00091541360.033
protein localizationGO:00081041910.032
regulation of phosphorylationGO:00423252480.032
purine nucleoside triphosphate metabolic processGO:00091441410.032
potassium ion transportGO:0006813970.032
negative regulation of response to stimulusGO:00485851550.031
peptide hormone secretionGO:0030072840.031
organic cyclic compound catabolic processGO:19013611750.031
muscle cell proliferationGO:0033002840.031
regulation of hormone secretionGO:00468831060.031
secretionGO:00469033070.030
organic anion transportGO:00157111320.030
positive regulation of nitrogen compound metabolic processGO:00511733340.030
epithelium developmentGO:0060429960.030
signal releaseGO:00230611450.030
amine metabolic processGO:0009308380.030
response to acid chemicalGO:00011012220.030
cellular catabolic processGO:00442482950.029
carbohydrate derivative biosynthetic processGO:19011371240.029
regulation of rna metabolic processGO:00512523910.029
positive regulation of rna biosynthetic processGO:19026801970.029
nucleoside metabolic processGO:00091161790.029
dna metabolic processGO:0006259960.029
regulation of kinase activityGO:00435491170.029
neuron projection morphogenesisGO:00488121220.029
g protein coupled receptor signaling pathwayGO:00071862420.029
regulation of cell developmentGO:00602842630.028
central nervous system developmentGO:00074173110.028
catabolic processGO:00090563510.028
positive regulation of phosphorylationGO:00423271770.028
ribonucleotide catabolic processGO:00092611360.028
regulation of exocytosisGO:0017157370.028
negative regulation of nitrogen compound metabolic processGO:00511721610.028
second messenger mediated signalingGO:0019932510.027
regulation of peptide transportGO:0090087870.027
response to external biotic stimulusGO:00432072210.027
positive regulation of catalytic activityGO:00430851840.027
anatomical structure morphogenesisGO:00096532980.027
regulation of nucleic acid templated transcriptionGO:19035063800.027
nucleobase containing compound catabolic processGO:00346551520.026
amide transportGO:00428861050.026
small gtpase mediated signal transductionGO:0007264360.026
inflammatory responseGO:00069541500.026
aromatic compound catabolic processGO:00194391680.026
immune system processGO:00023762040.026
cell morphogenesis involved in differentiationGO:00009041190.026
nucleotide catabolic processGO:00091661390.026
organic acid metabolic processGO:00060822920.025
glycerolipid metabolic processGO:0046486670.025
purine nucleoside catabolic processGO:00061521240.025
response to extracellular stimulusGO:00099913800.025
reproductionGO:00000032450.025
regulation of neuron differentiationGO:00456642080.025
macromolecule localizationGO:00330362520.025
signal transduction by phosphorylationGO:00230141440.025
neuron developmentGO:00486662860.025
glycosyl compound metabolic processGO:19016571820.025
regulation of secretion by cellGO:19035302080.024
motor neuron axon guidanceGO:000804510.024
multi organism reproductive processGO:00447032620.024
ribonucleoside catabolic processGO:00424541260.024
growthGO:00400071650.024
heart processGO:0003015570.024
cation transmembrane transportGO:00986552630.024
positive regulation of cellular component organizationGO:00511302000.024
purine containing compound biosynthetic processGO:0072522850.024
triglyceride homeostasisGO:007032820.024
organonitrogen compound catabolic processGO:19015651790.023
purine containing compound catabolic processGO:00725231380.023
protein homooligomerizationGO:0051260910.023
calcium ion transportGO:00068161310.023
heterocycle catabolic processGO:00467001670.023
insulin secretionGO:0030073690.023
apoptotic processGO:00069153810.023
positive regulation of protein modification processGO:00314011420.023
guanosine containing compound catabolic processGO:1901069710.022
regulation of hydrolase activityGO:00513361430.022
organ formationGO:004864530.022
regulation of nucleotide metabolic processGO:00061401170.022
organophosphate catabolic processGO:00464341480.022
regulation of cellular component biogenesisGO:0044087860.022
regulation of nucleotide biosynthetic processGO:0030808470.022
calcium mediated signalingGO:0019722230.022
macromolecular complex assemblyGO:00650032730.022
cellular nitrogen compound catabolic processGO:00442701630.021
regulation of phosphatidylinositol dephosphorylationGO:006030410.021
regulation of multicellular organismal developmentGO:20000263760.021
single organism organelle organizationGO:19025891800.021
purine nucleoside monophosphate metabolic processGO:0009126840.021
response to metal ionGO:00100382530.021
agingGO:00075682410.021
guanosine containing compound metabolic processGO:1901068740.020
organic hydroxy compound biosynthetic processGO:1901617510.020
regulation of system processGO:00440572080.020
response to monosaccharideGO:00342841590.020
enzyme linked receptor protein signaling pathwayGO:00071671160.020
localization of cellGO:00516742020.020
hormone transportGO:00099141210.020
negative regulation of transportGO:00510511360.020
multicellular organismal reproductive processGO:00486092330.020
cell projection morphogenesisGO:00488581230.020
neuron projection developmentGO:00311752730.020
l glutamate importGO:005193820.020
nucleic acid templated transcriptionGO:00976593790.020
gamete generationGO:00072761240.019
positive regulation of long term synaptic potentiationGO:190027340.019
cell growthGO:00160491040.019
negative regulation of vesicle fusionGO:003133920.019
purine ribonucleoside catabolic processGO:00461301240.019
negative regulation of signalingGO:00230571570.019
response to oxidative stressGO:00069791860.019
positive regulation of gene expressionGO:00106282440.019
regulation of cell differentiationGO:00455953200.018
positive regulation of protein phosphorylationGO:00019341350.018
regulation of peptide secretionGO:0002791820.018
cardiovascular system developmentGO:00723581340.018
positive regulation of cellular amino acid metabolic processGO:004576410.018
heart developmentGO:0007507720.018
striated muscle cell proliferationGO:001485590.018
nucleoside phosphate catabolic processGO:19012921400.018
forebrain developmentGO:0030900980.018
negative regulation of heart growthGO:006111730.018
regulation of protein kinase activityGO:00458591050.017
neurotransmitter transportGO:0006836420.017
regulation of cellular amino acid metabolic processGO:000652120.017
negative regulation of molecular functionGO:00440921330.017
negative regulation of cardiac muscle tissue developmentGO:005502630.017
glycosyl compound catabolic processGO:19016581260.017
locomotionGO:00400112370.017
cyclic purine nucleotide metabolic processGO:0052652620.017
multicellular organism growthGO:003526410.017
dendrite morphogenesisGO:0048813430.017
axon guidanceGO:0007411240.017
neurotransmitter secretionGO:0007269330.017
response to reactive oxygen speciesGO:00003021200.017
regulation of cardiac muscle tissue growthGO:0055021120.017
regulation of apoptotic processGO:00429813350.017
small molecule biosynthetic processGO:00442831240.017
regulation of ion transmembrane transporter activityGO:0032412480.016
negative regulation of cellular metabolic processGO:00313242810.016
divalent metal ion transportGO:00708381320.016
somatostatin receptor signaling pathwayGO:003816940.016
regulation of purine nucleotide biosynthetic processGO:1900371460.016
tissue developmentGO:00098882520.016
negative regulation of nucleotide metabolic processGO:0045980230.016
ribonucleoside metabolic processGO:00091191740.016
proteolysisGO:00065081750.016
regulation of catabolic processGO:00098941130.016
organic acid biosynthetic processGO:0016053830.016
regulation of metal ion transportGO:00109591180.016
carboxylic acid transportGO:00469421150.016
mapk cascadeGO:00001651400.016
negative regulation of secretion by cellGO:1903531720.016
regulation of insulin secretionGO:0050796650.016
positive regulation of mapk cascadeGO:0043410920.016
endomembrane system organizationGO:0010256480.016
purine nucleoside triphosphate catabolic processGO:00091461220.016
positive regulation of erk1 and erk2 cascadeGO:0070374290.016
jak stat cascadeGO:0007259260.016
sensory perception of painGO:0019233730.016
negative regulation of cardiac muscle tissue growthGO:005502230.015
cellular response to organic cyclic compoundGO:00714072020.015
purine ribonucleoside triphosphate catabolic processGO:00092071220.015
defense responseGO:00069521940.015
adult locomotory behaviorGO:000834440.015
regulation of mapk cascadeGO:00434081160.015
nitrogen compound transportGO:00717052290.015
catecholamine biosynthetic processGO:004242390.015
potassium ion transmembrane transportGO:0071805710.015
protein transportGO:00150311320.015
regulation of sodium ion transmembrane transporter activityGO:200064940.015
negative regulation of developmental growthGO:0048640150.015
carbohydrate derivative catabolic processGO:19011361470.015
positive regulation of cytosolic calcium ion concentrationGO:00072041220.015
regulation of purine nucleotide metabolic processGO:19005421150.014
response to radiationGO:00093141370.014
regulation of blood circulationGO:19035221100.014
cell cell signalingGO:00072673350.014
homeostatic processGO:00425923310.014
multicellular organismal homeostasisGO:0048871490.014
negative regulation of signal transductionGO:0009968830.014
peptide transportGO:0015833970.014
regulation of organ growthGO:0046620130.014
cellular response to stressGO:00335542690.014
somatostatin signaling pathwayGO:003817040.014
regulation of cellular amine metabolic processGO:003323880.014
regulation of dna metabolic processGO:0051052600.014
regulation of cell projection organizationGO:00313441750.014
metal ion transportGO:00300012890.014
actin mediated cell contractionGO:0070252120.014
protein complex subunit organizationGO:00718223020.014
muscle tissue developmentGO:0060537580.014
gastrulationGO:000736920.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
anterior posterior pattern specificationGO:000995210.014
negative regulation of cellular biosynthetic processGO:00313271610.013
response to glucocorticoidGO:00513842230.013
cellular response to endogenous stimulusGO:00714953770.013
purine nucleotide catabolic processGO:00061951360.013
regulation of ion homeostasisGO:2000021630.013
gtp metabolic processGO:0046039720.013
regulation of protein localizationGO:0032880810.013
embryo developmentGO:0009790490.013
positive regulation of nucleobase containing compound metabolic processGO:00459353190.013
exocytosisGO:0006887600.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.013
calcium ion homeostasisGO:00550741620.013
single organism intracellular transportGO:19025821660.013
mesonephric tubule developmentGO:0072164140.013
negative regulation of muscle cell apoptotic processGO:0010656210.013
regulation of protein serine threonine kinase activityGO:0071900640.013
embryonic pattern specificationGO:000988010.013
response to decreased oxygen levelsGO:00362932370.013
positive regulation of rna metabolic processGO:00512542030.013
positive regulation of ion transportGO:0043270940.013
positive regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124120.013
developmental growthGO:00485891000.013
response to glucoseGO:00097491360.013
phasic smooth muscle contractionGO:001482130.013
circulatory system processGO:00030131830.013
macromolecule catabolic processGO:0009057580.013
gtp catabolic processGO:0006184710.013
positive regulation of protein metabolic processGO:00512471780.013
synaptic transmissionGO:00072682350.012
axonogenesisGO:0007409710.012
sensory perception of light stimulusGO:005095330.012
camp biosynthetic processGO:0006171470.012
erk1 and erk2 cascadeGO:0070371480.012
activation of mapkkk activityGO:000018510.012
positive regulation of synaptic growth at neuromuscular junctionGO:004588710.012
positive regulation of blood circulationGO:1903524650.012
nucleoside monophosphate metabolic processGO:0009123930.012
muscle structure developmentGO:0061061870.012
ribonucleoside monophosphate metabolic processGO:0009161880.012
regulation of protein metabolic processGO:00512462890.012
detection of calcium ionGO:000551310.012
positive regulation of cellular component biogenesisGO:0044089550.012
regulation of transcription dna templatedGO:00063553740.012
regulation of protein modification processGO:00313991940.012
negative regulation of secretionGO:0051048820.012
single organism carbohydrate metabolic processGO:00447231180.012
positive regulation of transportGO:00510502450.012
chemical homeostasisGO:00488782920.012
negative regulation of ion transportGO:0043271510.012
detection of visible lightGO:000958430.012
heart morphogenesisGO:000300730.012
regulation of developmental growthGO:0048638450.012
negative regulation of organ growthGO:004662130.012
cellular response to alcoholGO:0097306870.012
positive regulation of biosynthetic processGO:00098913190.012
positive regulation of secretion by cellGO:19035321280.012
circulatory system developmentGO:00723591340.012
positive regulation of cellular amine metabolic processGO:003324030.011
positive regulation of cellular biosynthetic processGO:00313282950.011
male gamete generationGO:0048232990.011
positive regulation of exocytosisGO:0045921190.011
mitochondrion organizationGO:0007005350.011
regulation of synaptic growth at neuromuscular junctionGO:000858210.011
intracellular transportGO:00469071850.011
positive regulation of cellular protein metabolic processGO:00322701670.011
negative regulation of cellular component organizationGO:0051129830.011
cellular ion homeostasisGO:00068731840.011
saliva secretionGO:004654130.011
response to histamineGO:003477630.011
regulation of transmembrane transporter activityGO:0022898490.011
salivary gland developmentGO:000743130.011
positive regulation of immune system processGO:0002684900.011
negative regulation of purine nucleotide metabolic processGO:1900543230.011
positive regulation of homeostatic processGO:0032846490.011
regulation of signal transductionGO:00099663180.011
glutamine family amino acid metabolic processGO:0009064150.011
atp catabolic processGO:0006200540.011
regulation of muscle organ developmentGO:0048634260.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
regulation of cyclic nucleotide biosynthetic processGO:0030802450.011
acute inflammatory responseGO:0002526580.011
ion homeostasisGO:00508012120.011
positive regulation of cyclic nucleotide biosynthetic processGO:0030804340.011
response to ionizing radiationGO:0010212590.011
acid secretionGO:0046717480.011
regulation of nervous system developmentGO:00519602640.011
metal ion homeostasisGO:00550651860.011
camp metabolic processGO:0046058630.011
cell adhesionGO:00071551100.011
regulation of programmed cell deathGO:00430673410.011
response to peptide hormoneGO:00434342780.011
positive regulation of developmental processGO:00510942830.010
programmed cell deathGO:00125013920.010
peptidyl amino acid modificationGO:00181931260.010
tube developmentGO:0035295890.010
positive regulation of nervous system developmentGO:00519621780.010
divalent inorganic cation transportGO:00725111340.010
central nervous system neuron differentiationGO:0021953170.010
adaptation of signaling pathwayGO:0023058100.010
nucleoside triphosphate catabolic processGO:00091431230.010
cardiac chamber developmentGO:000320510.010
organic acid transportGO:00158491160.010
purine ribonucleoside monophosphate metabolic processGO:0009167840.010
protein catabolic processGO:0030163300.010

Tub disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.069
disease of anatomical entityDOID:700.069
sensory system diseaseDOID:005015500.035
brain diseaseDOID:93600.023
central nervous system diseaseDOID:33100.023
epilepsy syndromeDOID:182600.023
eye and adnexa diseaseDOID:149200.022
retinal diseaseDOID:567900.022
eye diseaseDOID:561400.022
electroclinical syndromeDOID:005070100.010