Rattus norvegicus

0 known processes

Mep1a

meprin 1 alpha

Mep1a biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550854120.608
inorganic ion transmembrane transportGO:00986602290.497
response to peptideGO:19016522920.347
choline transportGO:001587140.293
response to estrogenGO:00436272320.289
cellular response to endogenous stimulusGO:00714953770.278
chemical homeostasisGO:00488782920.266
oligopeptide transportGO:000685740.264
anion transportGO:00068201780.254
antibiotic transportGO:004289120.245
response to cytokineGO:00340972150.238
response to external biotic stimulusGO:00432072210.224
reproductive processGO:00224143720.209
nitrogen compound transportGO:00717052290.208
response to reactive oxygen speciesGO:00003021200.191
regulation of hormone levelsGO:00108171870.187
response to inorganic substanceGO:00100353770.186
cation transportGO:00068123820.179
response to peptide hormoneGO:00434342780.176
positive regulation of biosynthetic processGO:00098913190.174
ion transmembrane transportGO:00342203650.170
cation transmembrane transportGO:00986552630.166
carbohydrate derivative metabolic processGO:19011353460.162
organophosphate metabolic processGO:00196373700.158
regulation of molecular functionGO:00650093980.158
organic anion transportGO:00157111320.158
drug transmembrane transportGO:0006855130.155
programmed cell deathGO:00125013920.154
response to estradiolGO:00323551640.153
response to corticosteroidGO:00319602350.152
macromolecular complex subunit organizationGO:00439333390.150
glutathione transportGO:003463520.144
monocarboxylic acid transportGO:0015718520.144
response to glucocorticoidGO:00513842230.143
intracellular signal transductionGO:00355563140.141
positive regulation of transportGO:00510502450.137
regulation of cell proliferationGO:00421273590.135
organic hydroxy compound metabolic processGO:19016151150.135
lipid transportGO:0006869610.131
cytosolic calcium ion homeostasisGO:00514801400.130
nucleobase containing small molecule metabolic processGO:00550863160.130
amide transportGO:00428861050.126
peptide transportGO:0015833970.125
metal ion transportGO:00300012890.125
apoptotic processGO:00069153810.120
response to oxidative stressGO:00069791860.120
divalent metal ion transportGO:00708381320.119
organic acid metabolic processGO:00060822920.119
response to acid chemicalGO:00011012220.119
cellular component assemblyGO:00226073600.119
inorganic cation transmembrane transportGO:00986622020.118
cellular component movementGO:00069282480.117
central nervous system developmentGO:00074173110.116
positive regulation of nucleobase containing compound metabolic processGO:00459353190.115
protein complex biogenesisGO:00702712630.114
response to woundingGO:00096112540.112
regulation of transporter activityGO:0032409500.111
regulation of body fluid levelsGO:0050878900.107
single organism biosynthetic processGO:00447113420.105
monosaccharide metabolic processGO:0005996610.104
cellular response to steroid hormone stimulusGO:0071383930.103
regulation of ion transportGO:00432692450.102
hormone transportGO:00099141210.101
cellular chemical homeostasisGO:00550822470.100
epithelium developmentGO:0060429960.100
positive regulation of peptide hormone secretionGO:0090277500.098
behaviorGO:00076102050.098
cellular response to peptideGO:19016531330.098
reproductionGO:00000032450.098
cellular homeostasisGO:00197252520.096
protein complex subunit organizationGO:00718223020.096
response to monosaccharideGO:00342841590.094
carboxylic acid transportGO:00469421150.093
regulation of transmembrane transportGO:00347621220.093
response to biotic stimulusGO:00096072260.090
establishment or maintenance of transmembrane electrochemical gradientGO:001024810.090
developmental process involved in reproductionGO:00030061590.089
positive regulation of multicellular organismal processGO:00512403870.088
Zebrafish
organic acid transportGO:00158491160.088
forebrain developmentGO:0030900980.087
response to metal ionGO:00100382530.087
regulation of apoptotic processGO:00429813350.084
single organism organelle organizationGO:19025891800.084
carboxylic acid metabolic processGO:00197522890.083
multi organism reproductive processGO:00447032620.083
cell motilityGO:00488702020.082
negative regulation of programmed cell deathGO:00430691830.081
positive regulation of cell communicationGO:00106472710.080
response to other organismGO:00517072200.079
multicellular organismal reproductive processGO:00486092330.079
actin filament based processGO:0030029860.079
cellular response to peptide hormone stimulusGO:00713751200.078
homeostatic processGO:00425923310.078
cardiovascular system developmentGO:00723581340.078
Zebrafish
tube developmentGO:0035295890.077
positive regulation of molecular functionGO:00440932300.076
regulation of ion transmembrane transportGO:00347651210.075
hormone secretionGO:00468791150.074
single organism reproductive processGO:00447022970.074
positive regulation of nitrogen compound metabolic processGO:00511733340.074
cellular response to organonitrogen compoundGO:00714171970.073
urogenital system developmentGO:0001655780.073
epinephrine transportGO:004824170.072
female pregnancyGO:00075651220.072
protein complex assemblyGO:00064612630.071
head developmentGO:00603222470.070
cell cell signalingGO:00072673350.070
negative regulation of nitrogen compound metabolic processGO:00511721610.070
triglyceride metabolic processGO:0006641210.069
positive regulation of cellular component biogenesisGO:0044089550.068
negative regulation of cell deathGO:00605482290.067
lens development in camera type eyeGO:0002088130.067
divalent inorganic cation homeostasisGO:00725071650.067
divalent inorganic cation transportGO:00725111340.066
cellular response to nitrogen compoundGO:19016992100.065
cellular calcium ion homeostasisGO:00068741600.064
response to decreased oxygen levelsGO:00362932370.064
oxoacid metabolic processGO:00434362900.063
renal system developmentGO:0072001670.063
positive regulation of cell motilityGO:2000147970.063
negative regulation of cell communicationGO:00106481580.061
positive regulation of cellular biosynthetic processGO:00313282950.061
epinephrine secretionGO:004824260.061
drug transportGO:0015893180.061
response to hexoseGO:00097461440.061
cellular component biogenesisGO:00440853680.061
cellular amino acid metabolic processGO:00065201070.060
cell projection organizationGO:00300303020.059
single organism behaviorGO:00447081300.059
cellular response to stressGO:00335542690.059
positive regulation of phosphorylationGO:00423271770.059
growthGO:00400071650.058
response to molecule of bacterial originGO:00022371940.058
macromolecular complex assemblyGO:00650032730.058
negative regulation of apoptotic processGO:00430661810.058
positive regulation of signalingGO:00230562700.057
cytoskeleton organizationGO:00070101110.056
positive regulation of macromolecule biosynthetic processGO:00105572470.056
cognitionGO:0050890920.056
positive regulation of cellular component organizationGO:00511302000.055
positive regulation of gene expressionGO:00106282440.055
regulation of hormone secretionGO:00468831060.055
single organism catabolic processGO:00447122830.055
lipid localizationGO:0010876620.055
Worm
alpha amino acid metabolic processGO:1901605710.054
glycerolipid metabolic processGO:0046486670.054
positive regulation of cell proliferationGO:00082842490.054
response to lipopolysaccharideGO:00324961910.053
response to ethanolGO:00454711620.053
cellular glucan metabolic processGO:0006073230.052
immune system processGO:00023762040.052
multi multicellular organism processGO:00447061380.051
circadian rhythmGO:0007623880.051
calcium ion transport into cytosolGO:0060402380.051
regulation of catalytic activityGO:00507903040.050
purine ribonucleotide metabolic processGO:00091502270.050
organelle organizationGO:00069962660.050
secretion by cellGO:00329402480.050
regulation of phosphorus metabolic processGO:00511743490.049
peptide secretionGO:0002790860.048
regulation of anion transportGO:0044070430.048
regulation of cellular protein metabolic processGO:00322682670.048
cellular divalent inorganic cation homeostasisGO:00725031620.048
regulation of cell differentiationGO:00455953200.048
regulation of protein modification processGO:00313991940.047
cellular catabolic processGO:00442482950.047
cellular response to oxygen containing compoundGO:19017013860.047
positive regulation of developmental processGO:00510942830.046
Zebrafish
learning or memoryGO:0007611900.046
single organism intracellular transportGO:19025821660.045
regulation of phosphate metabolic processGO:00192203490.045
digestionGO:0007586260.045
regulation of cellular component biogenesisGO:0044087860.045
phospholipid metabolic processGO:0006644610.045
ribonucleotide metabolic processGO:00092592310.044
transcription from rna polymerase ii promoterGO:00063662520.044
response to glucoseGO:00097491360.044
regulation of peptide hormone secretionGO:0090276800.044
cellular response to hormone stimulusGO:00328702470.044
regulation of system processGO:00440572080.044
regulation of cellular localizationGO:00603412630.044
regulation of cell growthGO:0001558850.043
digestive system processGO:0022600240.042
cellular metal ion homeostasisGO:00068751720.042
actin filament organizationGO:0007015420.042
lipid metabolic processGO:00066292830.042
cellular response to lipidGO:00713962010.042
positive regulation of catalytic activityGO:00430851840.042
regulation of protein metabolic processGO:00512462890.042
sensory organ developmentGO:0007423740.042
brain developmentGO:00074202470.041
regulation of peptide transportGO:0090087870.041
regulation of calcium ion transportGO:0051924770.041
regulation of cell developmentGO:00602842630.040
phospholipase c activating g protein coupled receptor signaling pathwayGO:0007200270.040
camp metabolic processGO:0046058630.039
positive regulation of cell migrationGO:0030335960.039
regulation of heart contractionGO:0008016480.039
secretionGO:00469033070.039
cellular response to organic cyclic compoundGO:00714072020.039
cellular response to alcoholGO:0097306870.039
regulation of muscle contractionGO:0006937530.038
regulation of purine nucleotide metabolic processGO:19005421150.038
positive regulation of response to stimulusGO:00485842850.038
cellular lipid metabolic processGO:00442552080.038
negative regulation of signal transductionGO:0009968830.038
acylglycerol metabolic processGO:0006639210.038
anatomical structure morphogenesisGO:00096532980.037
Zebrafish Worm
cyclic nucleotide metabolic processGO:0009187800.037
sulfur compound transportGO:007234880.037
agingGO:00075682410.037
Worm
positive regulation of calcium ion transportGO:0051928360.036
sequestering of calcium ionGO:005120880.035
cation homeostasisGO:00550801950.035
peptide hormone secretionGO:0030072840.035
negative regulation of ion transportGO:0043271510.035
regulation of transcription from rna polymerase ii promoterGO:00063572340.035
lens fiber cell differentiationGO:007030630.035
regulation of serotonin secretionGO:001406250.035
signal releaseGO:00230611450.035
nucleoside phosphate biosynthetic processGO:19012931020.035
cellular response to oxidative stressGO:0034599760.034
positive regulation of phosphorus metabolic processGO:00105622620.034
protein homooligomerizationGO:0051260910.034
cellular ion homeostasisGO:00068731840.034
regulation of cellular component movementGO:00512701500.034
ossificationGO:0001503700.033
organic hydroxy compound transportGO:0015850770.033
multicellular organism reproductionGO:00325042330.033
sequestering of metal ionGO:005123890.033
regulation of cellular component organizationGO:00511283680.033
development of primary sexual characteristicsGO:00451371070.033
regulation of peptide secretionGO:0002791820.032
positive regulation of growthGO:0045927550.032
calcium ion transportGO:00068161310.032
sodium ion transmembrane transportGO:0035725670.032
sexual reproductionGO:00199531480.032
positive regulation of ion transportGO:0043270940.032
response to transition metal nanoparticleGO:19902671220.032
negative regulation of signalingGO:00230571570.032
dna metabolic processGO:0006259960.032
digestive tract developmentGO:0048565390.032
rna biosynthetic processGO:00327743800.032
rhythmic processGO:00485111560.032
monosaccharide transportGO:0015749310.032
negative regulation of luteinizing hormone secretionGO:003368540.032
carbohydrate metabolic processGO:00059751300.031
regulation of nucleotide metabolic processGO:00061401170.031
regulation of protein kinase activityGO:00458591050.031
regulation of growthGO:00400081050.031
multicellular organism growthGO:003526410.031
insulin secretionGO:0030073690.030
reproductive structure developmentGO:00486081280.030
positive regulation of cell differentiationGO:00455972170.030
positive regulation of hormone secretionGO:0046887650.030
digestive system developmentGO:0055123410.030
nucleoside phosphate metabolic processGO:00067532830.030
tissue developmentGO:00098882520.030
sex differentiationGO:00075481130.030
circadian regulation of gene expressionGO:003292230.030
positive regulation of intracellular signal transductionGO:19025331380.029
actin cytoskeleton organizationGO:0030036730.029
metal ion homeostasisGO:00550651860.029
regenerationGO:00310991630.029
regulation of phosphorylationGO:00423252480.029
glucose homeostasisGO:0042593750.029
hepaticobiliary system developmentGO:0061008900.029
maintenance of locationGO:0051235170.029
Worm
ion homeostasisGO:00508012120.029
regulation of calcium ion transmembrane transportGO:1903169180.029
hormone metabolic processGO:0042445690.028
negative regulation of macromolecule metabolic processGO:00106052600.028
nucleotide metabolic processGO:00091172790.028
isoprenoid metabolic processGO:0006720450.028
regulation of defense responseGO:0031347680.028
regulation of cell projection organizationGO:00313441750.028
catecholamine transportGO:0051937370.028
negative regulation of transportGO:00510511360.028
positive regulation of kinase activityGO:0033674770.027
response to calcium ionGO:0051592590.027
positive regulation of phosphate metabolic processGO:00459372620.027
sensory perceptionGO:00076001010.026
negative regulation of molecular functionGO:00440921330.026
cellular ketone metabolic processGO:0042180510.026
cell projection morphogenesisGO:00488581230.026
insulin like growth factor receptor signaling pathwayGO:004800930.026
multicellular organismal response to stressGO:0033555250.026
positive regulation of purine nucleotide metabolic processGO:1900544910.026
neutral lipid metabolic processGO:0006638210.026
kidney developmentGO:0001822670.026
toxin transportGO:190199830.026
multicellular organismal macromolecule metabolic processGO:0044259210.026
dephosphorylationGO:0016311980.026
ras protein signal transductionGO:0007265290.025
sodium independent organic anion transportGO:004325220.025
response to bacteriumGO:00096172000.025
ribose phosphate metabolic processGO:00196932350.025
organelle localizationGO:0051640550.025
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.025
positive regulation of protein kinase activityGO:0045860730.025
response to transforming growth factor betaGO:0071559460.025
purine containing compound metabolic processGO:00725212530.025
positive regulation of locomotionGO:00400171020.025
heterocycle catabolic processGO:00467001670.025
purine nucleotide metabolic processGO:00061632290.025
response to cocaineGO:0042220390.025
regulation of amino acid transportGO:0051955250.025
development of primary female sexual characteristicsGO:0046545560.024
telencephalon developmentGO:0021537620.024
cellular cation homeostasisGO:00300031800.024
body fluid secretionGO:0007589410.024
regulation of response to stressGO:00801341260.024
positive regulation of signal transductionGO:00099671750.024
response to molecule of fungal originGO:000223830.024
response to hypoxiaGO:00016662310.024
organic cation transportGO:0015695110.024
regulation of cell activationGO:0050865500.024
nucleic acid templated transcriptionGO:00976593790.024
organophosphate catabolic processGO:00464341480.024
regulation of transferase activityGO:00513381230.024
organonitrogen compound biosynthetic processGO:19015661670.024
cellular response to cgmpGO:007132120.024
cell activationGO:0001775970.024
regulation of insulin secretionGO:0050796650.023
calcium ion homeostasisGO:00550741620.023
protein oligomerizationGO:00512591910.023
regulation of transcription dna templatedGO:00063553740.023
positive regulation of rna metabolic processGO:00512542030.023
cellular response to insulin stimulusGO:0032869810.023
modified amino acid transportGO:0072337120.023
carbohydrate derivative catabolic processGO:19011361470.023
regulation of programmed cell deathGO:00430673410.023
organic substance catabolic processGO:19015753160.023
response to oxygen levelsGO:00704822650.023
respiratory system developmentGO:0060541450.023
cellular response to abiotic stimulusGO:0071214850.022
oxidation reduction processGO:00551143040.022
cellular amine metabolic processGO:0044106380.022
cytoplasmic transportGO:00164821150.022
regulation of defecationGO:200029210.022
lipid biosynthetic processGO:00086101280.022
gastric motilityGO:003548230.022
regulation of lipid metabolic processGO:0019216680.022
response to insulinGO:00328681330.022
release of sequestered calcium ion into cytosolGO:0051209250.022
protein phosphorylationGO:00064683450.022
glycerophospholipid metabolic processGO:0006650470.022
amino acid transportGO:0006865700.022
positive regulation of cellular protein metabolic processGO:00322701670.022
mononuclear cell proliferationGO:0032943290.022
gland developmentGO:00487321550.021
female sex differentiationGO:0046660590.021
positive regulation of cytosolic calcium ion concentrationGO:00072041220.021
response to dexamethasoneGO:0071548490.021
regulation of phospholipase activityGO:0010517120.021
gamete generationGO:00072761240.021
locomotory exploration behaviorGO:003564110.021
regulation of cell motilityGO:20001451310.021
negative regulation of gene expressionGO:00106291990.021
circulatory system developmentGO:00723591340.021
Zebrafish
carbohydrate homeostasisGO:0033500750.021
regulation of locomotionGO:00400121480.020
carbohydrate derivative biosynthetic processGO:19011371240.020
response to ammonium ionGO:0060359710.020
response to extracellular stimulusGO:00099913800.020
negative regulation of peptide hormone secretionGO:0090278300.020
nucleotide biosynthetic processGO:0009165980.020
rna metabolic processGO:00160704060.020
bile acid and bile salt transportGO:0015721120.020
cell migrationGO:00164771970.020
regulation of kinase activityGO:00435491170.020
intracellular transportGO:00469071850.020
exploration behaviorGO:003564010.020
negative regulation of secretionGO:0051048820.020
positive regulation of rna biosynthetic processGO:19026801970.019
ribonucleotide catabolic processGO:00092611360.019
positive regulation of transmembrane transportGO:0034764250.019
regulation of leukocyte proliferationGO:0070663260.019
aromatic compound catabolic processGO:00194391680.019
synaptic transmissionGO:00072682350.019
carnitine transportGO:001587910.019
regulation of signal transductionGO:00099663180.019
cell cycleGO:00070491010.019
regulation of nervous system developmentGO:00519602640.019
renal system processGO:0003014400.019
positive regulation of secretionGO:00510471400.019
regulation of mapk cascadeGO:00434081160.019
regulation of secretionGO:00510462240.019
negative regulation of sequestering of calcium ionGO:0051283250.019
response to growth factorGO:00708481890.018
neuron projection developmentGO:00311752730.018
positive regulation of nucleotide metabolic processGO:0045981910.018
regulation of neuron deathGO:19012141150.018
neuron differentiationGO:00301823680.018
organ formationGO:004864530.018
positive regulation of cell activationGO:0050867340.018
negative regulation of hormone secretionGO:0046888460.018
regulation of cation channel activityGO:2001257230.018
amine metabolic processGO:0009308380.018
female gonad developmentGO:0008585530.018
ovulation cycleGO:0042698670.018
response to axon injuryGO:0048678590.018
response to vitamin eGO:0033197240.018
negative regulation of biosynthetic processGO:00098901680.018
regulation of cellular amino acid metabolic processGO:000652120.018
purine ribonucleoside metabolic processGO:00461281680.018
positive regulation of protein metabolic processGO:00512471780.018
cellular response to hexose stimulusGO:0071331650.018
negative regulation of cell proliferationGO:00082851190.018
terpenoid metabolic processGO:0006721370.017
regulation of inflammatory responseGO:0050727480.017
regulation of cellular ketone metabolic processGO:0010565270.017
catechol containing compound biosynthetic processGO:000971390.017
purine ribonucleoside triphosphate catabolic processGO:00092071220.017
memoryGO:0007613540.017
positive regulation of secretion by cellGO:19035321280.017
cellular modified amino acid metabolic processGO:0006575610.017
positive regulation of ion transmembrane transportGO:0034767240.017
positive regulation of renin secretion into blood streamGO:190013510.017
positive regulation of nervous system developmentGO:00519621780.017
positive regulation of serotonin secretionGO:001406410.017
ribose phosphate biosynthetic processGO:0046390870.017
positive regulation of leukocyte degranulationGO:004330240.017
response to mechanical stimulusGO:00096121340.017
localization of cellGO:00516742020.017
lymphocyte proliferationGO:0046651290.017
leukocyte activationGO:0045321760.017
regulation of fat cell differentiationGO:004559830.017
dopamine transportGO:0015872180.017
regulation of actin filament based processGO:0032970420.017
developmental growthGO:00485891000.017
small gtpase mediated signal transductionGO:0007264360.017
anatomical structure formation involved in morphogenesisGO:0048646830.016
Zebrafish
positive regulation of protein modification processGO:00314011420.016
regulation of dna metabolic processGO:0051052600.016
regulation of lymphocyte proliferationGO:0050670260.016
cellular response to cytokine stimulusGO:00713451270.016
striated muscle contractionGO:0006941440.016
locomotionGO:00400112370.016
Worm
spermatogenesisGO:0007283990.016
cellular response to glucose stimulusGO:0071333650.016
endocrine hormone secretionGO:0060986210.016
phenol containing compound metabolic processGO:0018958300.016
regulation of protein phosphorylationGO:00019321830.016
negative regulation of secretion by cellGO:1903531720.016
regulation of muscle system processGO:0090257790.016
regulation of hydrolase activityGO:00513361430.016
organophosphate biosynthetic processGO:00904071430.016
nucleotide catabolic processGO:00091661390.016
positive regulation of peptide secretionGO:0002793520.016
positive regulation of insulin secretionGO:0032024360.016
negative regulation of cellular biosynthetic processGO:00313271610.016
negative regulation of metabolic processGO:00098923310.016
regulation of organelle organizationGO:0033043800.016
regulation of smooth muscle cell proliferationGO:0048660750.016
reproductive system developmentGO:00614581280.016
purine ribonucleotide catabolic processGO:00091541360.016
regulation of metal ion transportGO:00109591180.016
positive regulation of cell developmentGO:00107201760.016
protein kinase c activating g protein coupled receptor signaling pathwayGO:0007205120.016
defecationGO:003042110.016
hormone mediated signaling pathwayGO:0009755230.015
negative regulation of multicellular organismal processGO:00512412030.015
response to purine containing compoundGO:00140741260.015
positive regulation of transferase activityGO:0051347810.015
cellular response to inorganic substanceGO:0071241650.015
negative regulation of nucleobase containing compound metabolic processGO:00459341530.015
purine ribonucleoside triphosphate metabolic processGO:00092051400.015
response to hydrogen peroxideGO:0042542890.015
acid secretionGO:0046717480.015
regulation of blood pressureGO:0008217830.015
regulation of leukocyte activationGO:0002694450.015
response to organophosphorusGO:00466831020.015
hexose transportGO:0008645290.015
carbohydrate biosynthetic processGO:0016051420.015
purine nucleotide catabolic processGO:00061951360.015
positive regulation of transcription dna templatedGO:00458931970.015
synaptic transmission dopaminergicGO:0001963110.015
ribonucleoside metabolic processGO:00091191740.015
epoxygenase p450 pathwayGO:001937310.014
cellular response to transforming growth factor beta stimulusGO:0071560410.014
alcohol metabolic processGO:0006066770.014
transcription dna templatedGO:00063513770.014
response to carbohydrateGO:00097431830.014
cellular response to metal ionGO:0071248550.014
positive regulation of interleukin 6 productionGO:003275580.014
muscle system processGO:00030121150.014
vesicle mediated transportGO:00161921810.014
positive regulation of muscle contractionGO:0045933220.014

Mep1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
renal tubular transport diseaseDOID:44700.155
kidney diseaseDOID:55700.155
disease of anatomical entityDOID:700.155
urinary system diseaseDOID:1800.155
nervous system diseaseDOID:86300.018
sensory system diseaseDOID:005015500.014
eye and adnexa diseaseDOID:149200.014