Rattus norvegicus

185 known processes

Axl

Axl receptor tyrosine kinase

Axl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of programmed cell deathGO:00430673410.344
cellular response to platelet derived growth factor stimulusGO:003612070.255
blood coagulationGO:0007596260.253
cell migration involved in kidney developmentGO:003578720.246
enzyme linked receptor protein signaling pathwayGO:00071671160.223
defense responseGO:00069521940.220
cellular response to vascular endothelial growth factor stimulusGO:003592460.200
metanephric glomerulus morphogenesisGO:007227510.181
regulation of blood coagulationGO:003019390.164
regulation of apoptotic processGO:00429813350.160
positive regulation of cell communicationGO:00106472710.154
cellular component movementGO:00069282480.150
neuron deathGO:00709971270.148
positive regulation of phosphate metabolic processGO:00459372620.141
pro t cell differentiationGO:000257210.139
positive regulation of signalingGO:00230562700.135
positive regulation of mapk cascadeGO:0043410920.127
glomerulus morphogenesisGO:007210210.118
s shaped body morphogenesisGO:007205020.112
regulation of cellular component movementGO:00512701500.110
positive regulation of macromolecule biosynthetic processGO:00105572470.109
apoptotic processGO:00069153810.106
localization of cellGO:00516742020.103
positive regulation of phosphorylationGO:00423271770.100
locomotionGO:00400112370.100
positive regulation of cell proliferationGO:00082842490.098
cellular response to hormone stimulusGO:00328702470.093
regulation of cell proliferationGO:00421273590.092
regulation of stem cell differentiationGO:200073620.090
positive regulation of molecular functionGO:00440932300.084
response to woundingGO:00096112540.084
positive regulation of smooth muscle cell proliferationGO:0048661510.084
response to biotic stimulusGO:00096072260.084
glomerulus vasculature developmentGO:007201260.080
positive regulation of signal transductionGO:00099671750.078
positive regulation of cellular protein metabolic processGO:00322701670.077
tissue remodelingGO:0048771400.077
glomerulus developmentGO:0032835100.074
positive regulation of nitrogen compound metabolic processGO:00511733340.074
comma shaped body morphogenesisGO:007204920.074
cell projection organizationGO:00300303020.073
carbohydrate derivative metabolic processGO:19011353460.072
positive regulation of cellular biosynthetic processGO:00313282950.071
peptidyl amino acid modificationGO:00181931260.071
metanephric mesenchymal cell migrationGO:003578920.071
cell motilityGO:00488702020.070
positive regulation of phosphorus metabolic processGO:00105622620.070
lymphoid progenitor cell differentiationGO:000232020.069
positive regulation of protein metabolic processGO:00512471780.068
vascular endothelial growth factor receptor signaling pathwayGO:004801080.067
vasculature developmentGO:0001944700.067
single organism reproductive processGO:00447022970.066
single organism cell adhesionGO:0098602460.066
neuron apoptotic processGO:0051402880.065
myeloid progenitor cell differentiationGO:000231810.064
positive regulation of transportGO:00510502450.063
macromolecular complex subunit organizationGO:00439333390.062
coagulationGO:0050817280.062
platelet activationGO:003016880.061
cellular response to organic cyclic compoundGO:00714072020.059
regulation of cell migrationGO:00303341280.059
regulation of system processGO:00440572080.058
negative regulation of cell deathGO:00605482290.058
embryonic skeletal system developmentGO:004870630.058
metanephric glomerulus developmentGO:007222430.057
positive regulation of multicellular organismal processGO:00512403870.057
intracellular signal transductionGO:00355563140.056
wound healingGO:00420601220.054
metanephric s shaped body morphogenesisGO:007228420.054
cellular response to growth factor stimulusGO:00713631620.054
regulation of response to stressGO:00801341260.054
lipid metabolic processGO:00066292830.053
protein phosphorylationGO:00064683450.052
circulatory system developmentGO:00723591340.051
cell migrationGO:00164771970.050
growthGO:00400071650.050
cellular response to endogenous stimulusGO:00714953770.049
regulation of smooth muscle cell proliferationGO:0048660750.048
inflammatory responseGO:00069541500.047
regulation of rna biosynthetic processGO:20011413810.047
regulation of response to external stimulusGO:00321011060.046
reproductive processGO:00224143720.046
regulation of locomotionGO:00400121480.046
positive regulation of developmental processGO:00510942830.046
positive regulation of response to stimulusGO:00485842850.045
regulation of multicellular organismal developmentGO:20000263760.045
response to growth factorGO:00708481890.045
regulation of platelet activationGO:001054320.044
salivary gland developmentGO:000743130.044
protein complex subunit organizationGO:00718223020.043
regulation of hydrolase activityGO:00513361430.043
sensory organ developmentGO:0007423740.042
platelet derived growth factor receptor alpha signaling pathwayGO:003579010.042
regulation of neuron deathGO:19012141150.042
regulation of cellular component organizationGO:00511283680.042
cell morphogenesisGO:00009021420.041
positive regulation of myeloid leukocyte differentiationGO:000276370.041
regulation of response to woundingGO:1903034690.041
response to oxidative stressGO:00069791860.040
positive regulation of catalytic activityGO:00430851840.040
response to mechanical stimulusGO:00096121340.039
heart morphogenesisGO:000300730.039
regulation of mapk cascadeGO:00434081160.039
cellular component assemblyGO:00226073600.038
organelle organizationGO:00069962660.038
positive regulation of apoptotic processGO:00430651540.038
neuron projection developmentGO:00311752730.038
cardiovascular system developmentGO:00723581340.038
response to molecule of bacterial originGO:00022371940.038
organophosphate metabolic processGO:00196373700.038
positive regulation of protein phosphorylationGO:00019341350.037
response to oxygen levelsGO:00704822650.037
immune system processGO:00023762040.037
cell projection assemblyGO:0030031210.036
regulation of catalytic activityGO:00507903040.036
regulation of signal transductionGO:00099663180.036
positive regulation of protein kinase activityGO:0045860730.036
regulation of protein metabolic processGO:00512462890.035
positive regulation of cell differentiationGO:00455972170.035
response to glucocorticoidGO:00513842230.034
response to external biotic stimulusGO:00432072210.034
cellular response to steroid hormone stimulusGO:0071383930.034
organonitrogen compound biosynthetic processGO:19015661670.034
negative regulation of b cell differentiationGO:004557810.034
multicellular organism reproductionGO:00325042330.034
vesicle mediated transportGO:00161921810.034
cell chemotaxisGO:0060326310.034
multicellular organismal homeostasisGO:0048871490.033
regulation of nucleic acid templated transcriptionGO:19035063800.033
regulation of cell differentiationGO:00455953200.033
signal transduction by phosphorylationGO:00230141440.033
endocytosisGO:0006897840.033
tissue developmentGO:00098882520.033
nucleic acid templated transcriptionGO:00976593790.033
regulation of cell projection organizationGO:00313441750.032
regulation of cellular protein metabolic processGO:00322682670.032
regulation of phosphorylationGO:00423252480.032
positive regulation of blood coagulationGO:003019440.031
single organism biosynthetic processGO:00447113420.031
positive regulation of transferase activityGO:0051347810.031
regulation of molecular functionGO:00650093980.030
response to inorganic substanceGO:00100353770.030
metanephric comma shaped body morphogenesisGO:007227820.030
organic acid metabolic processGO:00060822920.030
positive regulation of intracellular signal transductionGO:19025331380.030
leydig cell differentiationGO:003332780.030
programmed cell deathGO:00125013920.030
positive regulation of biosynthetic processGO:00098913190.029
blood vessel developmentGO:0001568690.029
positive regulation of interleukin 6 productionGO:003275580.029
cellular component biogenesisGO:00440853680.028
positive regulation of locomotionGO:00400171020.028
multicellular organismal reproductive processGO:00486092330.027
organ morphogenesisGO:0009887750.026
cellular response to oxygen containing compoundGO:19017013860.026
negative regulation of cell differentiationGO:0045596990.026
mapk cascadeGO:00001651400.026
skeletal system developmentGO:0001501410.026
regulation of coagulationGO:0050818110.026
regulation of chemotaxisGO:0050920290.026
rna biosynthetic processGO:00327743800.026
positive regulation of protein modification processGO:00314011420.025
innate immune responseGO:0045087350.025
development of primary female sexual characteristicsGO:0046545560.025
response to corticosteroidGO:00319602350.025
kidney developmentGO:0001822670.025
positive regulation of growthGO:0045927550.025
small gtpase mediated signal transductionGO:0007264360.024
reproductionGO:00000032450.024
regulation of nervous system developmentGO:00519602640.024
positive regulation of kinase activityGO:0033674770.024
regulation of phosphate metabolic processGO:00192203490.024
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.023
eye developmentGO:0001654500.023
organ regenerationGO:00311001010.023
response to hypoxiaGO:00016662310.023
collagen metabolic processGO:0032963210.023
response to bacteriumGO:00096172000.023
regulation of smooth muscle contractionGO:0006940290.023
aminoglycan biosynthetic processGO:000602340.023
protein transportGO:00150311320.022
positive regulation of gene expressionGO:00106282440.022
positive regulation of protein export from nucleusGO:004682730.022
response to estrogenGO:00436272320.022
tissue homeostasisGO:0001894280.022
positive regulation of cellular component organizationGO:00511302000.022
cellular response to lipidGO:00713962010.022
carboxylic acid metabolic processGO:00197522890.022
regulation of transcription dna templatedGO:00063553740.022
cellular response to organonitrogen compoundGO:00714171970.021
developmental process involved in reproductionGO:00030061590.021
cell activationGO:0001775970.021
regulation of protein modification processGO:00313991940.021
positive regulation of cellular amine metabolic processGO:003324030.021
cellular amine metabolic processGO:0044106380.021
positive regulation of cellular amino acid metabolic processGO:004576410.020
agingGO:00075682410.020
muscle contractionGO:0006936880.020
response to decreased oxygen levelsGO:00362932370.020
ras protein signal transductionGO:0007265290.020
transcription from rna polymerase ii promoterGO:00063662520.020
peptidyl tyrosine phosphorylationGO:0018108720.020
response to reactive oxygen speciesGO:00003021200.020
negative regulation of programmed cell deathGO:00430691830.020
hematopoietic progenitor cell differentiationGO:000224420.020
kidney mesenchyme developmentGO:007207420.020
cellular hormone metabolic processGO:0034754490.020
renal system developmentGO:0072001670.019
response to glucoseGO:00097491360.019
gliogenesisGO:0042063930.019
cell growthGO:00160491040.019
neurological system processGO:00508772190.019
positive regulation of cell deathGO:00109421840.019
smooth muscle cell proliferationGO:0048659770.018
regulation of bmp signaling pathwayGO:003051020.018
positive regulation of cell migrationGO:0030335960.018
smooth muscle contractionGO:0006939370.018
bone resorptionGO:0045453180.018
establishment of protein localizationGO:00451841410.018
neuronal action potentialGO:0019228350.018
positive regulation of nucleobase containing compound metabolic processGO:00459353190.018
b cell differentiationGO:003018320.018
rho protein signal transductionGO:0007266110.018
response to transforming growth factor betaGO:0071559460.018
platelet aggregationGO:007052740.018
neuron differentiationGO:00301823680.018
positive regulation of rna biosynthetic processGO:19026801970.018
organic substance catabolic processGO:19015753160.018
negative regulation of macromolecule metabolic processGO:00106052600.018
sex differentiationGO:00075481130.018
salivary gland morphogenesisGO:000743510.018
maternal process involved in female pregnancyGO:0060135380.017
actin cytoskeleton organizationGO:0030036730.017
regulation of cellular amino acid metabolic processGO:000652120.017
metanephros developmentGO:0001656140.017
multi organism reproductive processGO:00447032620.017
positive regulation of hemostasisGO:190004840.017
regulation of anatomical structure sizeGO:00900661350.017
regulation of b cell differentiationGO:004557710.017
response to nutrient levelsGO:00316673700.017
regulation of protein kinase activityGO:00458591050.017
spindle organizationGO:000705120.017
cellular response to cytokine stimulusGO:00713451270.017
muscle system processGO:00030121150.017
cytokine mediated signaling pathwayGO:0019221430.017
axis specificationGO:000979840.017
regulation of immune system processGO:00026821230.017
anatomical structure homeostasisGO:0060249290.017
positive regulation of coagulationGO:005082050.016
regulation of blood vessel sizeGO:0050880890.016
negative regulation of immune system processGO:0002683390.016
response to other organismGO:00517072200.016
neuron developmentGO:00486662860.016
urogenital system developmentGO:0001655780.016
carbohydrate derivative biosynthetic processGO:19011371240.016
regulation of cellular localizationGO:00603412630.015
regulation of small gtpase mediated signal transductionGO:0051056480.015
catabolic processGO:00090563510.015
female sex differentiationGO:0046660590.015
homeostasis of number of cellsGO:0048872100.015
homeostatic processGO:00425923310.015
cellular component morphogenesisGO:00329891550.015
response to toxic substanceGO:00096361330.015
positive regulation of intracellular protein transportGO:0090316200.015
secretion by cellGO:00329402480.015
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.015
anatomical structure morphogenesisGO:00096532980.015
positive regulation of cell projection organizationGO:00313461110.015
positive regulation of transcription dna templatedGO:00458931970.014
regulation of cellular amine metabolic processGO:003323880.014
central nervous system developmentGO:00074173110.014
regulation of tube sizeGO:0035150890.014
cellular component maintenanceGO:004395440.014
regulation of osteoclast differentiationGO:004567080.014
nephron developmentGO:0072006220.014
cellular response to glucocorticoid stimulusGO:0071385680.014
negative regulation of apoptotic processGO:00430661810.014
peptidyl tyrosine modificationGO:0018212720.014
regulation of neuron projection developmentGO:00109751610.014
regulation of kinase activityGO:00435491170.014
regulation of catabolic processGO:00098941130.014
response to vitaminGO:00332731310.014
positive regulation of fibroblast proliferationGO:0048146150.014
positive regulation of cellular component movementGO:00512721020.014
transforming growth factor beta receptor signaling pathwayGO:0007179180.014
positive regulation of cell motilityGO:2000147970.014
regulation of phosphorus metabolic processGO:00511743490.013
cellular ketone metabolic processGO:0042180510.013
negative regulation of multicellular organismal processGO:00512412030.013
response to cytokineGO:00340972150.013
regulation of hormone levelsGO:00108171870.013
amine metabolic processGO:0009308380.013
regulation of body fluid levelsGO:0050878900.013
organic anion transportGO:00157111320.013
positive regulation of hydrolase activityGO:0051345860.013
sexual reproductionGO:00199531480.013
mast cell migrationGO:009753140.013
positive regulation of nervous system developmentGO:00519621780.013
regulation of cell developmentGO:00602842630.013
regulation of muscle system processGO:0090257790.013
bone developmentGO:0060348250.013
behaviorGO:00076102050.013
embryonic pattern specificationGO:000988010.012
nucleobase containing small molecule metabolic processGO:00550863160.012
smooth muscle cell migrationGO:0014909360.012
cell type specific apoptotic processGO:00972851340.012
response to lipopolysaccharideGO:00324961910.012
protein complex assemblyGO:00064612630.012
cellular amino acid metabolic processGO:00065201070.012
cell projection morphogenesisGO:00488581230.012
rna metabolic processGO:00160704060.012
hemostasisGO:0007599260.012
response to increased oxygen levelsGO:0036296450.012
positive regulation of programmed cell deathGO:00430681570.012
secretionGO:00469033070.012
response to fluid shear stressGO:0034405160.012
multicellular organismal macromolecule metabolic processGO:0044259210.012
gamete generationGO:00072761240.012
action potentialGO:0001508540.012
cytokine biosynthetic processGO:004208930.012
regulation of protein phosphorylationGO:00019321830.012
macromolecule localizationGO:00330362520.012
anterior posterior pattern specificationGO:000995210.011
regulation of establishment of protein localizationGO:0070201690.011
positive regulation of neuron differentiationGO:00456661260.011
oxoacid metabolic processGO:00434362900.011
cation homeostasisGO:00550801950.011
reproductive structure developmentGO:00486081280.011
cell adhesionGO:00071551100.011
anatomical structure maturationGO:007169520.011
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051220.011
eye morphogenesisGO:004859240.011
muscle cell proliferationGO:0033002840.011
single organism catabolic processGO:00447122830.011
palate developmentGO:006002120.011
developmental growthGO:00485891000.011
vascular endothelial growth factor signaling pathwayGO:003808440.011
cellular homeostasisGO:00197252520.011
negative regulation of metabolic processGO:00098923310.010
transmembrane transportGO:00550854120.010
protein localizationGO:00081041910.010
response to hexoseGO:00097461440.010
regulation of cell adhesionGO:0030155520.010
cell migration involved in metanephros developmentGO:003578820.010
retina development in camera type eyeGO:0060041270.010
phospholipid metabolic processGO:0006644610.010
positive regulation of rna metabolic processGO:00512542030.010
positive regulation of neuron deathGO:1901216430.010
blood vessel morphogenesisGO:0048514580.010
cytoskeleton organizationGO:00070101110.010

Axl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.027
eye and adnexa diseaseDOID:149200.027
nervous system diseaseDOID:86300.027
eye diseaseDOID:561400.027
retinal degenerationDOID:846600.027
retinal diseaseDOID:567900.027
sensory system diseaseDOID:005015500.027
musculoskeletal system diseaseDOID:1700.019
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011
cancerDOID:16200.011
gastrointestinal system cancerDOID:311900.011