| cation transmembrane transport | GO:0098655 | 263 | 0.255 | |
| protein complex biogenesis | GO:0070271 | 263 | 0.241 | |
| protein complex subunit organization | GO:0071822 | 302 | 0.239 | Yeast |
| ion transmembrane transport | GO:0034220 | 365 | 0.238 | |
| protein oligomerization | GO:0051259 | 191 | 0.202 | |
| response to inorganic substance | GO:0010035 | 377 | 0.190 | |
| protein complex assembly | GO:0006461 | 263 | 0.169 | |
| macromolecular complex assembly | GO:0065003 | 273 | 0.161 | |
| cation transport | GO:0006812 | 382 | 0.155 | |
| muscle contraction | GO:0006936 | 88 | 0.152 | |
| inorganic ion transmembrane transport | GO:0098660 | 229 | 0.107 | |
| potassium ion transport | GO:0006813 | 97 | 0.101 | |
| metal ion transport | GO:0030001 | 289 | 0.096 | |
| neuron differentiation | GO:0030182 | 368 | 0.093 | |
| inorganic cation transmembrane transport | GO:0098662 | 202 | 0.093 | |
| transmembrane transport | GO:0055085 | 412 | 0.089 | |
| protein homooligomerization | GO:0051260 | 91 | 0.080 | |
| regulation of transcription dna templated | GO:0006355 | 374 | 0.079 | |
| cellular response to oxygen containing compound | GO:1901701 | 386 | 0.077 | |
| monovalent inorganic cation transport | GO:0015672 | 172 | 0.075 | |
| regulation of rna metabolic process | GO:0051252 | 391 | 0.074 | |
| muscle system process | GO:0003012 | 115 | 0.072 | |
| anion transport | GO:0006820 | 178 | 0.071 | |
| cellular component assembly | GO:0022607 | 360 | 0.069 | |
| positive regulation of ion transport | GO:0043270 | 94 | 0.065 | |
| response to mechanical stimulus | GO:0009612 | 134 | 0.065 | |
| organic anion transport | GO:0015711 | 132 | 0.058 | |
| cellular homeostasis | GO:0019725 | 252 | 0.058 | |
| cellular component biogenesis | GO:0044085 | 368 | 0.058 | |
| blood circulation | GO:0008015 | 183 | 0.058 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 316 | 0.057 | |
| cellular component movement | GO:0006928 | 248 | 0.055 | |
| macromolecular complex subunit organization | GO:0043933 | 339 | 0.055 | Yeast |
| chemical homeostasis | GO:0048878 | 292 | 0.053 | |
| cell migration | GO:0016477 | 197 | 0.051 | |
| regulation of ion transport | GO:0043269 | 245 | 0.051 | |
| oxidation reduction process | GO:0055114 | 304 | 0.050 | |
| rna biosynthetic process | GO:0032774 | 380 | 0.048 | |
| circulatory system development | GO:0072359 | 134 | 0.046 | |
| cardiac muscle contraction | GO:0060048 | 27 | 0.046 | |
| regulation of multicellular organismal development | GO:2000026 | 376 | 0.046 | |
| nucleic acid templated transcription | GO:0097659 | 379 | 0.045 | |
| response to blue light | GO:0009637 | 1 | 0.045 | |
| organic substance catabolic process | GO:1901575 | 316 | 0.045 | |
| response to cytokine | GO:0034097 | 215 | 0.045 | |
| potassium ion transmembrane transport | GO:0071805 | 71 | 0.044 | |
| programmed cell death | GO:0012501 | 392 | 0.041 | |
| transcription dna templated | GO:0006351 | 377 | 0.040 | |
| neuron projection development | GO:0031175 | 273 | 0.040 | |
| response to peptide hormone | GO:0043434 | 278 | 0.040 | |
| response to molecule of bacterial origin | GO:0002237 | 194 | 0.039 | |
| cellular chemical homeostasis | GO:0055082 | 247 | 0.039 | |
| homeostatic process | GO:0042592 | 331 | 0.036 | |
| cellular response to endogenous stimulus | GO:0071495 | 377 | 0.036 | |
| cell cell signaling | GO:0007267 | 335 | 0.036 | |
| inflammatory response | GO:0006954 | 150 | 0.035 | |
| nucleoside metabolic process | GO:0009116 | 179 | 0.034 | |
| catabolic process | GO:0009056 | 351 | 0.034 | |
| regulation of cell proliferation | GO:0042127 | 359 | 0.034 | |
| response to wounding | GO:0009611 | 254 | 0.034 | |
| response to tumor necrosis factor | GO:0034612 | 56 | 0.034 | |
| response to hypoxia | GO:0001666 | 231 | 0.033 | |
| locomotion | GO:0040011 | 237 | 0.032 | |
| response to transition metal nanoparticle | GO:1990267 | 122 | 0.032 | |
| nucleoside phosphate metabolic process | GO:0006753 | 283 | 0.032 | |
| cellular response to external stimulus | GO:0071496 | 118 | 0.032 | |
| purine containing compound metabolic process | GO:0072521 | 253 | 0.031 | |
| regulation of striated muscle contraction | GO:0006942 | 21 | 0.031 | |
| response to carbohydrate | GO:0009743 | 183 | 0.031 | |
| ribonucleoside metabolic process | GO:0009119 | 174 | 0.031 | |
| central nervous system development | GO:0007417 | 311 | 0.030 | |
| response to hexose | GO:0009746 | 144 | 0.030 | |
| response to interleukin 1 | GO:0070555 | 55 | 0.030 | |
| positive regulation of transport | GO:0051050 | 245 | 0.030 | |
| cellular catabolic process | GO:0044248 | 295 | 0.030 | |
| regulation of metal ion transport | GO:0010959 | 118 | 0.030 | |
| regulation of muscle system process | GO:0090257 | 79 | 0.030 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 334 | 0.029 | |
| muscle structure development | GO:0061061 | 87 | 0.029 | Fly |
| regulation of phosphate metabolic process | GO:0019220 | 349 | 0.029 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 144 | 0.029 | |
| negative regulation of transcription dna templated | GO:0045892 | 116 | 0.029 | |
| response to ketone | GO:1901654 | 182 | 0.029 | |
| organic acid transport | GO:0015849 | 116 | 0.028 | |
| purine ribonucleoside metabolic process | GO:0046128 | 168 | 0.028 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 141 | 0.028 | |
| positive regulation of developmental process | GO:0051094 | 283 | 0.028 | |
| cell motility | GO:0048870 | 202 | 0.027 | |
| regulation of cell differentiation | GO:0045595 | 320 | 0.027 | |
| positive regulation of biosynthetic process | GO:0009891 | 319 | 0.027 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 122 | 0.027 | |
| regulation of catabolic process | GO:0009894 | 113 | 0.027 | |
| nucleotide metabolic process | GO:0009117 | 279 | 0.027 | |
| purine nucleoside metabolic process | GO:0042278 | 169 | 0.027 | |
| cellular response to stress | GO:0033554 | 269 | 0.026 | |
| circulatory system process | GO:0003013 | 183 | 0.026 | |
| response to decreased oxygen levels | GO:0036293 | 237 | 0.026 | |
| cellular potassium ion transport | GO:0071804 | 72 | 0.026 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 115 | 0.026 | |
| glycosyl compound catabolic process | GO:1901658 | 126 | 0.026 | |
| regulation of membrane repolarization | GO:0060306 | 1 | 0.026 | |
| positive regulation of cell death | GO:0010942 | 184 | 0.026 | |
| cellular response to mechanical stimulus | GO:0071260 | 48 | 0.026 | |
| cellular response to tumor necrosis factor | GO:0071356 | 46 | 0.025 | |
| regulation of catalytic activity | GO:0050790 | 304 | 0.025 | |
| organelle organization | GO:0006996 | 266 | 0.025 | Yeast Worm |
| cardiovascular system development | GO:0072358 | 134 | 0.025 | |
| membrane depolarization during action potential | GO:0086010 | 1 | 0.025 | |
| l glutamate import | GO:0051938 | 2 | 0.025 | |
| response to metal ion | GO:0010038 | 253 | 0.025 | |
| striated muscle contraction | GO:0006941 | 44 | 0.025 | |
| regulation of apoptotic process | GO:0042981 | 335 | 0.024 | |
| organophosphate metabolic process | GO:0019637 | 370 | 0.024 | |
| organonitrogen compound catabolic process | GO:1901565 | 179 | 0.024 | |
| carbohydrate derivative metabolic process | GO:1901135 | 346 | 0.024 | |
| nucleotide catabolic process | GO:0009166 | 139 | 0.024 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 117 | 0.023 | |
| glycosyl compound metabolic process | GO:1901657 | 182 | 0.023 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 141 | 0.023 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 123 | 0.023 | |
| regulation of nucleic acid templated transcription | GO:1903506 | 380 | 0.023 | |
| locomotor rhythm | GO:0045475 | 1 | 0.022 | |
| regulation of molecular function | GO:0065009 | 398 | 0.022 | |
| ribonucleoside catabolic process | GO:0042454 | 126 | 0.022 | |
| cardiac muscle cell contraction | GO:0086003 | 10 | 0.022 | |
| regulation of neurogenesis | GO:0050767 | 247 | 0.022 | |
| negative regulation of gene expression | GO:0010629 | 199 | 0.022 | |
| positive regulation of apoptotic process | GO:0043065 | 154 | 0.022 | |
| carboxylic acid metabolic process | GO:0019752 | 289 | 0.021 | |
| cellular response to abiotic stimulus | GO:0071214 | 85 | 0.021 | |
| nucleoside phosphate catabolic process | GO:1901292 | 140 | 0.021 | |
| cell projection organization | GO:0030030 | 302 | 0.021 | |
| response to monosaccharide | GO:0034284 | 159 | 0.021 | |
| intracellular signal transduction | GO:0035556 | 314 | 0.021 | |
| response to glucose | GO:0009749 | 136 | 0.021 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 122 | 0.021 | |
| regulation of membrane potential | GO:0042391 | 110 | 0.020 | |
| defense response | GO:0006952 | 194 | 0.020 | Fly |
| neurological system process | GO:0050877 | 219 | 0.020 | |
| response to radiation | GO:0009314 | 137 | 0.020 | |
| cellular response to acid chemical | GO:0071229 | 75 | 0.020 | |
| neuron projection morphogenesis | GO:0048812 | 122 | 0.020 | |
| endocytosis | GO:0006897 | 84 | 0.020 | |
| lipid metabolic process | GO:0006629 | 283 | 0.020 | |
| carboxylic acid transport | GO:0046942 | 115 | 0.020 | |
| cellular macromolecule localization | GO:0070727 | 122 | 0.020 | |
| positive regulation of cell differentiation | GO:0045597 | 217 | 0.019 | |
| regulation of neuron differentiation | GO:0045664 | 208 | 0.019 | |
| response to acid chemical | GO:0001101 | 222 | 0.019 | |
| positive regulation of rna metabolic process | GO:0051254 | 203 | 0.019 | |
| anatomical structure morphogenesis | GO:0009653 | 298 | 0.019 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 2 | 0.019 | |
| response to oxygen levels | GO:0070482 | 265 | 0.019 | |
| regulation of system process | GO:0044057 | 208 | 0.019 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 252 | 0.019 | |
| regulation of secretion | GO:0051046 | 224 | 0.019 | |
| localization of cell | GO:0051674 | 202 | 0.019 | |
| signal release | GO:0023061 | 145 | 0.019 | |
| cellular lipid metabolic process | GO:0044255 | 208 | 0.019 | |
| membrane organization | GO:0061024 | 94 | 0.018 | |
| multi multicellular organism process | GO:0044706 | 138 | 0.018 | |
| renal system development | GO:0072001 | 67 | 0.018 | |
| response to insulin | GO:0032868 | 133 | 0.018 | |
| single organism catabolic process | GO:0044712 | 283 | 0.018 | |
| rna metabolic process | GO:0016070 | 406 | 0.018 | |
| regulation of nervous system development | GO:0051960 | 264 | 0.017 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 122 | 0.017 | |
| carbohydrate derivative catabolic process | GO:1901136 | 147 | 0.017 | |
| positive regulation of molecular function | GO:0044093 | 230 | 0.017 | |
| positive regulation of programmed cell death | GO:0043068 | 157 | 0.017 | |
| negative regulation of cell differentiation | GO:0045596 | 99 | 0.017 | |
| cellular response to metal ion | GO:0071248 | 55 | 0.017 | |
| nitrogen compound transport | GO:0071705 | 229 | 0.017 | |
| cellular amino acid metabolic process | GO:0006520 | 107 | 0.017 | |
| brain development | GO:0007420 | 247 | 0.017 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 55 | 0.017 | |
| cellular amine metabolic process | GO:0044106 | 38 | 0.017 | |
| choline transport | GO:0015871 | 4 | 0.017 | |
| neuron development | GO:0048666 | 286 | 0.017 | |
| positive regulation of cellular catabolic process | GO:0031331 | 71 | 0.017 | |
| response to nutrient levels | GO:0031667 | 370 | 0.017 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 148 | 0.017 | |
| cellular response to cytokine stimulus | GO:0071345 | 127 | 0.016 | |
| ribose phosphate metabolic process | GO:0019693 | 235 | 0.016 | |
| purine nucleotide catabolic process | GO:0006195 | 136 | 0.016 | |
| regulation of cell development | GO:0060284 | 263 | 0.016 | |
| circadian rhythm | GO:0007623 | 88 | 0.016 | |
| calcium ion homeostasis | GO:0055074 | 162 | 0.016 | |
| amino acid transport | GO:0006865 | 70 | 0.016 | |
| response to ethanol | GO:0045471 | 162 | 0.016 | |
| behavior | GO:0007610 | 205 | 0.016 | |
| negative regulation of cell communication | GO:0010648 | 158 | 0.016 | |
| purine ribonucleoside catabolic process | GO:0046130 | 124 | 0.016 | |
| regulation of potassium ion transport | GO:0043266 | 29 | 0.016 | |
| positive regulation of gene expression | GO:0010628 | 244 | 0.016 | |
| regulation of cell migration | GO:0030334 | 128 | 0.016 | |
| regulation of mapk cascade | GO:0043408 | 116 | 0.016 | |
| regulation of intracellular signal transduction | GO:1902531 | 218 | 0.016 | |
| cardiac conduction | GO:0061337 | 2 | 0.015 | |
| head development | GO:0060322 | 247 | 0.015 | |
| regulation of sodium ion transmembrane transporter activity | GO:2000649 | 4 | 0.015 | |
| hormone transport | GO:0009914 | 121 | 0.015 | |
| positive regulation of potassium ion transmembrane transport | GO:1901381 | 4 | 0.015 | |
| immune system process | GO:0002376 | 204 | 0.015 | |
| regulation of homeostatic process | GO:0032844 | 101 | 0.015 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 140 | 0.015 | |
| organophosphate catabolic process | GO:0046434 | 148 | 0.015 | |
| cellular response to growth factor stimulus | GO:0071363 | 162 | 0.015 | |
| regulation of hormone levels | GO:0010817 | 187 | 0.015 | |
| multi organism reproductive process | GO:0044703 | 262 | 0.015 | |
| reproductive process | GO:0022414 | 372 | 0.015 | |
| regulation of rna biosynthetic process | GO:2001141 | 381 | 0.015 | |
| positive regulation of organic acid transport | GO:0032892 | 22 | 0.014 | |
| response to extracellular stimulus | GO:0009991 | 380 | 0.014 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 84 | 0.014 | |
| sodium ion transport | GO:0006814 | 82 | 0.014 | |
| purine containing compound catabolic process | GO:0072523 | 138 | 0.014 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 197 | 0.014 | |
| secretion by cell | GO:0032940 | 248 | 0.014 | |
| positive regulation of cell proliferation | GO:0008284 | 249 | 0.014 | |
| synaptic transmission | GO:0007268 | 235 | 0.014 | |
| anion transmembrane transport | GO:0098656 | 77 | 0.014 | |
| negative regulation of metabolic process | GO:0009892 | 331 | 0.014 | |
| cell projection morphogenesis | GO:0048858 | 123 | 0.014 | |
| single organism biosynthetic process | GO:0044711 | 342 | 0.014 | |
| response to lipopolysaccharide | GO:0032496 | 191 | 0.014 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.014 | |
| organophosphate biosynthetic process | GO:0090407 | 143 | 0.013 | |
| fatty acid oxidation | GO:0019395 | 29 | 0.013 | |
| circadian regulation of gene expression | GO:0032922 | 3 | 0.013 | |
| heterocycle catabolic process | GO:0046700 | 167 | 0.013 | |
| response to calcium ion | GO:0051592 | 59 | 0.013 | |
| response to alkaloid | GO:0043279 | 132 | 0.013 | |
| apoptotic process | GO:0006915 | 381 | 0.013 | |
| response to other organism | GO:0051707 | 220 | 0.013 | Fly |
| vesicle mediated transport | GO:0016192 | 181 | 0.013 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 163 | 0.013 | |
| ion homeostasis | GO:0050801 | 212 | 0.013 | |
| regulation of cell motility | GO:2000145 | 131 | 0.013 | |
| phosphatidylethanolamine metabolic process | GO:0046337 | 1 | 0.013 | |
| single organism behavior | GO:0044708 | 130 | 0.013 | |
| positive regulation of transcription dna templated | GO:0045893 | 197 | 0.013 | |
| regulation of neuron projection development | GO:0010975 | 161 | 0.013 | |
| female pregnancy | GO:0007565 | 122 | 0.013 | |
| regulation of phosphorylation | GO:0042325 | 248 | 0.013 | |
| protein tetramerization | GO:0051262 | 38 | 0.013 | |
| positive regulation of phosphorylation | GO:0042327 | 177 | 0.013 | |
| single organism membrane organization | GO:0044802 | 74 | 0.013 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 262 | 0.013 | |
| regulation of programmed cell death | GO:0043067 | 341 | 0.013 | |
| organic cyclic compound catabolic process | GO:1901361 | 175 | 0.013 | |
| purine ribonucleotide metabolic process | GO:0009150 | 227 | 0.013 | |
| membrane repolarization | GO:0086009 | 1 | 0.013 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 83 | 0.013 | |
| gliogenesis | GO:0042063 | 93 | 0.013 | |
| regulation of cellular catabolic process | GO:0031329 | 101 | 0.012 | |
| cellular response to inorganic substance | GO:0071241 | 65 | 0.012 | |
| purine ribonucleotide catabolic process | GO:0009154 | 136 | 0.012 | |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.012 | |
| protein homotetramerization | GO:0051289 | 25 | 0.012 | |
| cell morphogenesis | GO:0000902 | 142 | 0.012 | |
| nucleobase containing compound catabolic process | GO:0034655 | 152 | 0.012 | |
| negative regulation of cellular component organization | GO:0051129 | 83 | 0.012 | Yeast |
| aging | GO:0007568 | 241 | 0.012 | |
| positive regulation of catalytic activity | GO:0043085 | 184 | 0.012 | |
| actin filament based process | GO:0030029 | 86 | 0.012 | Yeast |
| negative regulation of neurogenesis | GO:0050768 | 78 | 0.012 | |
| purine nucleoside catabolic process | GO:0006152 | 124 | 0.012 | |
| regulation of cellular component organization | GO:0051128 | 368 | 0.012 | Yeast |
| proteolysis | GO:0006508 | 175 | 0.012 | |
| multicellular organismal reproductive process | GO:0048609 | 233 | 0.012 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 319 | 0.012 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 27 | 0.012 | |
| divalent metal ion transport | GO:0070838 | 132 | 0.012 | |
| positive regulation of smooth muscle cell proliferation | GO:0048661 | 51 | 0.012 | |
| negative regulation of cellular metabolic process | GO:0031324 | 281 | 0.012 | |
| response to testosterone | GO:0033574 | 55 | 0.012 | |
| regulation of phagocytosis engulfment | GO:0060099 | 4 | 0.012 | |
| regulation of blood vessel size | GO:0050880 | 89 | 0.011 | |
| regulation of cellular component movement | GO:0051270 | 150 | 0.011 | |
| actin mediated cell contraction | GO:0070252 | 12 | 0.011 | |
| heart process | GO:0003015 | 57 | 0.011 | |
| regulation of stem cell differentiation | GO:2000736 | 2 | 0.011 | |
| negative regulation of cell death | GO:0060548 | 229 | 0.011 | |
| sodium ion transmembrane transport | GO:0035725 | 67 | 0.011 | |
| nucleoside catabolic process | GO:0009164 | 126 | 0.011 | |
| cellular response to lipid | GO:0071396 | 201 | 0.011 | |
| cellular response to nitrogen compound | GO:1901699 | 210 | 0.011 | |
| negative regulation of response to stimulus | GO:0048585 | 155 | 0.011 | |
| heart development | GO:0007507 | 72 | 0.011 | |
| glucose homeostasis | GO:0042593 | 75 | 0.011 | |
| positive regulation of cell communication | GO:0010647 | 271 | 0.011 | |
| cell growth | GO:0016049 | 104 | 0.011 | |
| response to toxic substance | GO:0009636 | 133 | 0.011 | |
| regulation of reactive oxygen species biosynthetic process | GO:1903426 | 5 | 0.011 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 118 | 0.011 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 153 | 0.011 | |
| positive regulation of cellular component movement | GO:0051272 | 102 | 0.011 | |
| amine metabolic process | GO:0009308 | 38 | 0.011 | |
| oxoacid metabolic process | GO:0043436 | 290 | 0.011 | |
| organic acid metabolic process | GO:0006082 | 292 | 0.011 | |
| neurotransmitter transport | GO:0006836 | 42 | 0.011 | |
| cellular response to lipopolysaccharide | GO:0071222 | 55 | 0.011 | |
| cellular response to molecule of bacterial origin | GO:0071219 | 56 | 0.011 | |
| regulation of insulin secretion | GO:0050796 | 65 | 0.011 | |
| cellular response to insulin stimulus | GO:0032869 | 81 | 0.011 | |
| response to ph | GO:0009268 | 27 | 0.011 | |
| positive regulation of catabolic process | GO:0009896 | 78 | 0.011 | |
| ras protein signal transduction | GO:0007265 | 29 | 0.010 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 148 | 0.010 | |
| muscle organ development | GO:0007517 | 50 | 0.010 | |
| negative regulation of rna metabolic process | GO:0051253 | 123 | 0.010 | |
| regulation of anatomical structure size | GO:0090066 | 135 | 0.010 | Yeast |
| protein phosphorylation | GO:0006468 | 345 | 0.010 | |
| cytoplasmic transport | GO:0016482 | 115 | 0.010 | |
| regulation of locomotion | GO:0040012 | 148 | 0.010 | |
| regulation of neuron death | GO:1901214 | 115 | 0.010 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 124 | 0.010 | |
| cell adhesion | GO:0007155 | 110 | 0.010 | |
| purine nucleotide metabolic process | GO:0006163 | 229 | 0.010 | |