IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Coro6

coronin 6

(Aliases: MGC112600)

Ensembl: ENSRNOG00000014496
Entrez: 245982
RGD: 708560
UniProtKB: Q920J3

Process Predictions
Disease Predictions

Coro6 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cation transmembrane transport	GO:0098655	263	0.255
protein complex biogenesis	GO:0070271	263	0.241
protein complex subunit organization	GO:0071822	302	0.239	Yeast
ion transmembrane transport	GO:0034220	365	0.238
protein oligomerization	GO:0051259	191	0.202
response to inorganic substance	GO:0010035	377	0.190
protein complex assembly	GO:0006461	263	0.169
macromolecular complex assembly	GO:0065003	273	0.161
cation transport	GO:0006812	382	0.155
muscle contraction	GO:0006936	88	0.152
inorganic ion transmembrane transport	GO:0098660	229	0.107
potassium ion transport	GO:0006813	97	0.101
metal ion transport	GO:0030001	289	0.096
neuron differentiation	GO:0030182	368	0.093
inorganic cation transmembrane transport	GO:0098662	202	0.093
transmembrane transport	GO:0055085	412	0.089
protein homooligomerization	GO:0051260	91	0.080
regulation of transcription dna templated	GO:0006355	374	0.079
cellular response to oxygen containing compound	GO:1901701	386	0.077
monovalent inorganic cation transport	GO:0015672	172	0.075
regulation of rna metabolic process	GO:0051252	391	0.074
muscle system process	GO:0003012	115	0.072
anion transport	GO:0006820	178	0.071
cellular component assembly	GO:0022607	360	0.069
positive regulation of ion transport	GO:0043270	94	0.065
response to mechanical stimulus	GO:0009612	134	0.065
organic anion transport	GO:0015711	132	0.058
cellular homeostasis	GO:0019725	252	0.058
cellular component biogenesis	GO:0044085	368	0.058
blood circulation	GO:0008015	183	0.058
nucleobase containing small molecule metabolic process	GO:0055086	316	0.057
cellular component movement	GO:0006928	248	0.055
macromolecular complex subunit organization	GO:0043933	339	0.055	Yeast
chemical homeostasis	GO:0048878	292	0.053
cell migration	GO:0016477	197	0.051
regulation of ion transport	GO:0043269	245	0.051
oxidation reduction process	GO:0055114	304	0.050
rna biosynthetic process	GO:0032774	380	0.048
circulatory system development	GO:0072359	134	0.046
cardiac muscle contraction	GO:0060048	27	0.046
regulation of multicellular organismal development	GO:2000026	376	0.046
nucleic acid templated transcription	GO:0097659	379	0.045
response to blue light	GO:0009637	1	0.045
organic substance catabolic process	GO:1901575	316	0.045
response to cytokine	GO:0034097	215	0.045
potassium ion transmembrane transport	GO:0071805	71	0.044
programmed cell death	GO:0012501	392	0.041
transcription dna templated	GO:0006351	377	0.040
neuron projection development	GO:0031175	273	0.040
response to peptide hormone	GO:0043434	278	0.040
response to molecule of bacterial origin	GO:0002237	194	0.039
cellular chemical homeostasis	GO:0055082	247	0.039
homeostatic process	GO:0042592	331	0.036
cellular response to endogenous stimulus	GO:0071495	377	0.036
cell cell signaling	GO:0007267	335	0.036
inflammatory response	GO:0006954	150	0.035
nucleoside metabolic process	GO:0009116	179	0.034
catabolic process	GO:0009056	351	0.034
regulation of cell proliferation	GO:0042127	359	0.034
response to wounding	GO:0009611	254	0.034
response to tumor necrosis factor	GO:0034612	56	0.034
response to hypoxia	GO:0001666	231	0.033
locomotion	GO:0040011	237	0.032
response to transition metal nanoparticle	GO:1990267	122	0.032
nucleoside phosphate metabolic process	GO:0006753	283	0.032
cellular response to external stimulus	GO:0071496	118	0.032
purine containing compound metabolic process	GO:0072521	253	0.031
regulation of striated muscle contraction	GO:0006942	21	0.031
response to carbohydrate	GO:0009743	183	0.031
ribonucleoside metabolic process	GO:0009119	174	0.031
central nervous system development	GO:0007417	311	0.030
response to hexose	GO:0009746	144	0.030
response to interleukin 1	GO:0070555	55	0.030
positive regulation of transport	GO:0051050	245	0.030
cellular catabolic process	GO:0044248	295	0.030
regulation of metal ion transport	GO:0010959	118	0.030
regulation of muscle system process	GO:0090257	79	0.030
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.029
muscle structure development	GO:0061061	87	0.029	Fly
regulation of phosphate metabolic process	GO:0019220	349	0.029
nucleoside triphosphate metabolic process	GO:0009141	144	0.029
negative regulation of transcription dna templated	GO:0045892	116	0.029
response to ketone	GO:1901654	182	0.029
organic acid transport	GO:0015849	116	0.028
purine ribonucleoside metabolic process	GO:0046128	168	0.028
ribonucleoside triphosphate metabolic process	GO:0009199	141	0.028
positive regulation of developmental process	GO:0051094	283	0.028
cell motility	GO:0048870	202	0.027
regulation of cell differentiation	GO:0045595	320	0.027
positive regulation of biosynthetic process	GO:0009891	319	0.027
ribonucleoside triphosphate catabolic process	GO:0009203	122	0.027
regulation of catabolic process	GO:0009894	113	0.027
nucleotide metabolic process	GO:0009117	279	0.027
purine nucleoside metabolic process	GO:0042278	169	0.027
cellular response to stress	GO:0033554	269	0.026
circulatory system process	GO:0003013	183	0.026
response to decreased oxygen levels	GO:0036293	237	0.026
cellular potassium ion transport	GO:0071804	72	0.026
regulation of purine nucleotide metabolic process	GO:1900542	115	0.026
glycosyl compound catabolic process	GO:1901658	126	0.026
regulation of membrane repolarization	GO:0060306	1	0.026
positive regulation of cell death	GO:0010942	184	0.026
cellular response to mechanical stimulus	GO:0071260	48	0.026
cellular response to tumor necrosis factor	GO:0071356	46	0.025
regulation of catalytic activity	GO:0050790	304	0.025
organelle organization	GO:0006996	266	0.025	Yeast Worm
cardiovascular system development	GO:0072358	134	0.025
membrane depolarization during action potential	GO:0086010	1	0.025
l glutamate import	GO:0051938	2	0.025
response to metal ion	GO:0010038	253	0.025
striated muscle contraction	GO:0006941	44	0.025
regulation of apoptotic process	GO:0042981	335	0.024
organophosphate metabolic process	GO:0019637	370	0.024
organonitrogen compound catabolic process	GO:1901565	179	0.024
carbohydrate derivative metabolic process	GO:1901135	346	0.024
nucleotide catabolic process	GO:0009166	139	0.024
negative regulation of nucleic acid templated transcription	GO:1903507	117	0.023
glycosyl compound metabolic process	GO:1901657	182	0.023
purine nucleoside triphosphate metabolic process	GO:0009144	141	0.023
nucleoside triphosphate catabolic process	GO:0009143	123	0.023
regulation of nucleic acid templated transcription	GO:1903506	380	0.023
locomotor rhythm	GO:0045475	1	0.022
regulation of molecular function	GO:0065009	398	0.022
ribonucleoside catabolic process	GO:0042454	126	0.022
cardiac muscle cell contraction	GO:0086003	10	0.022
regulation of neurogenesis	GO:0050767	247	0.022
negative regulation of gene expression	GO:0010629	199	0.022
positive regulation of apoptotic process	GO:0043065	154	0.022
carboxylic acid metabolic process	GO:0019752	289	0.021
cellular response to abiotic stimulus	GO:0071214	85	0.021
nucleoside phosphate catabolic process	GO:1901292	140	0.021
cell projection organization	GO:0030030	302	0.021
response to monosaccharide	GO:0034284	159	0.021
intracellular signal transduction	GO:0035556	314	0.021
response to glucose	GO:0009749	136	0.021
purine nucleoside triphosphate catabolic process	GO:0009146	122	0.021
regulation of membrane potential	GO:0042391	110	0.020
defense response	GO:0006952	194	0.020	Fly
neurological system process	GO:0050877	219	0.020
response to radiation	GO:0009314	137	0.020
cellular response to acid chemical	GO:0071229	75	0.020
neuron projection morphogenesis	GO:0048812	122	0.020
endocytosis	GO:0006897	84	0.020
lipid metabolic process	GO:0006629	283	0.020
carboxylic acid transport	GO:0046942	115	0.020
cellular macromolecule localization	GO:0070727	122	0.020
positive regulation of cell differentiation	GO:0045597	217	0.019
regulation of neuron differentiation	GO:0045664	208	0.019
response to acid chemical	GO:0001101	222	0.019
positive regulation of rna metabolic process	GO:0051254	203	0.019
anatomical structure morphogenesis	GO:0009653	298	0.019
regulation of cellular amino acid metabolic process	GO:0006521	2	0.019
response to oxygen levels	GO:0070482	265	0.019
regulation of system process	GO:0044057	208	0.019
transcription from rna polymerase ii promoter	GO:0006366	252	0.019
regulation of secretion	GO:0051046	224	0.019
localization of cell	GO:0051674	202	0.019
signal release	GO:0023061	145	0.019
cellular lipid metabolic process	GO:0044255	208	0.019
membrane organization	GO:0061024	94	0.018
multi multicellular organism process	GO:0044706	138	0.018
renal system development	GO:0072001	67	0.018
response to insulin	GO:0032868	133	0.018
single organism catabolic process	GO:0044712	283	0.018
rna metabolic process	GO:0016070	406	0.018
regulation of nervous system development	GO:0051960	264	0.017
purine ribonucleoside triphosphate catabolic process	GO:0009207	122	0.017
carbohydrate derivative catabolic process	GO:1901136	147	0.017
positive regulation of molecular function	GO:0044093	230	0.017
positive regulation of programmed cell death	GO:0043068	157	0.017
negative regulation of cell differentiation	GO:0045596	99	0.017
cellular response to metal ion	GO:0071248	55	0.017
nitrogen compound transport	GO:0071705	229	0.017
cellular amino acid metabolic process	GO:0006520	107	0.017
brain development	GO:0007420	247	0.017
purine nucleoside monophosphate catabolic process	GO:0009128	55	0.017
cellular amine metabolic process	GO:0044106	38	0.017
choline transport	GO:0015871	4	0.017
neuron development	GO:0048666	286	0.017
positive regulation of cellular catabolic process	GO:0031331	71	0.017
response to nutrient levels	GO:0031667	370	0.017
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.017
cellular response to cytokine stimulus	GO:0071345	127	0.016
ribose phosphate metabolic process	GO:0019693	235	0.016
purine nucleotide catabolic process	GO:0006195	136	0.016
regulation of cell development	GO:0060284	263	0.016
circadian rhythm	GO:0007623	88	0.016
calcium ion homeostasis	GO:0055074	162	0.016
amino acid transport	GO:0006865	70	0.016
response to ethanol	GO:0045471	162	0.016
behavior	GO:0007610	205	0.016
negative regulation of cell communication	GO:0010648	158	0.016
purine ribonucleoside catabolic process	GO:0046130	124	0.016
regulation of potassium ion transport	GO:0043266	29	0.016
positive regulation of gene expression	GO:0010628	244	0.016
regulation of cell migration	GO:0030334	128	0.016
regulation of mapk cascade	GO:0043408	116	0.016
regulation of intracellular signal transduction	GO:1902531	218	0.016
cardiac conduction	GO:0061337	2	0.015
head development	GO:0060322	247	0.015
regulation of sodium ion transmembrane transporter activity	GO:2000649	4	0.015
hormone transport	GO:0009914	121	0.015
positive regulation of potassium ion transmembrane transport	GO:1901381	4	0.015
immune system process	GO:0002376	204	0.015
regulation of homeostatic process	GO:0032844	101	0.015
purine ribonucleoside triphosphate metabolic process	GO:0009205	140	0.015
organophosphate catabolic process	GO:0046434	148	0.015
cellular response to growth factor stimulus	GO:0071363	162	0.015
regulation of hormone levels	GO:0010817	187	0.015
multi organism reproductive process	GO:0044703	262	0.015
reproductive process	GO:0022414	372	0.015
regulation of rna biosynthetic process	GO:2001141	381	0.015
positive regulation of organic acid transport	GO:0032892	22	0.014
response to extracellular stimulus	GO:0009991	380	0.014
purine ribonucleoside monophosphate metabolic process	GO:0009167	84	0.014
sodium ion transport	GO:0006814	82	0.014
purine containing compound catabolic process	GO:0072523	138	0.014
positive regulation of rna biosynthetic process	GO:1902680	197	0.014
secretion by cell	GO:0032940	248	0.014
positive regulation of cell proliferation	GO:0008284	249	0.014
synaptic transmission	GO:0007268	235	0.014
anion transmembrane transport	GO:0098656	77	0.014
negative regulation of metabolic process	GO:0009892	331	0.014
cell projection morphogenesis	GO:0048858	123	0.014
single organism biosynthetic process	GO:0044711	342	0.014
response to lipopolysaccharide	GO:0032496	191	0.014
developmental process involved in reproduction	GO:0003006	159	0.014
organophosphate biosynthetic process	GO:0090407	143	0.013
fatty acid oxidation	GO:0019395	29	0.013
circadian regulation of gene expression	GO:0032922	3	0.013
heterocycle catabolic process	GO:0046700	167	0.013
response to calcium ion	GO:0051592	59	0.013
response to alkaloid	GO:0043279	132	0.013
apoptotic process	GO:0006915	381	0.013
response to other organism	GO:0051707	220	0.013	Fly
vesicle mediated transport	GO:0016192	181	0.013
cellular nitrogen compound catabolic process	GO:0044270	163	0.013
ion homeostasis	GO:0050801	212	0.013
regulation of cell motility	GO:2000145	131	0.013
phosphatidylethanolamine metabolic process	GO:0046337	1	0.013
single organism behavior	GO:0044708	130	0.013
positive regulation of transcription dna templated	GO:0045893	197	0.013
regulation of neuron projection development	GO:0010975	161	0.013
female pregnancy	GO:0007565	122	0.013
regulation of phosphorylation	GO:0042325	248	0.013
protein tetramerization	GO:0051262	38	0.013
positive regulation of phosphorylation	GO:0042327	177	0.013
single organism membrane organization	GO:0044802	74	0.013
positive regulation of phosphate metabolic process	GO:0045937	262	0.013
regulation of programmed cell death	GO:0043067	341	0.013
organic cyclic compound catabolic process	GO:1901361	175	0.013
purine ribonucleotide metabolic process	GO:0009150	227	0.013
membrane repolarization	GO:0086009	1	0.013
anatomical structure formation involved in morphogenesis	GO:0048646	83	0.013
gliogenesis	GO:0042063	93	0.013
regulation of cellular catabolic process	GO:0031329	101	0.012
cellular response to inorganic substance	GO:0071241	65	0.012
purine ribonucleotide catabolic process	GO:0009154	136	0.012
small gtpase mediated signal transduction	GO:0007264	36	0.012
protein homotetramerization	GO:0051289	25	0.012
cell morphogenesis	GO:0000902	142	0.012
nucleobase containing compound catabolic process	GO:0034655	152	0.012
negative regulation of cellular component organization	GO:0051129	83	0.012	Yeast
aging	GO:0007568	241	0.012
positive regulation of catalytic activity	GO:0043085	184	0.012
actin filament based process	GO:0030029	86	0.012	Yeast
negative regulation of neurogenesis	GO:0050768	78	0.012
purine nucleoside catabolic process	GO:0006152	124	0.012
regulation of cellular component organization	GO:0051128	368	0.012	Yeast
proteolysis	GO:0006508	175	0.012
multicellular organismal reproductive process	GO:0048609	233	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.012
regulation of cellular ketone metabolic process	GO:0010565	27	0.012
divalent metal ion transport	GO:0070838	132	0.012
positive regulation of smooth muscle cell proliferation	GO:0048661	51	0.012
negative regulation of cellular metabolic process	GO:0031324	281	0.012
response to testosterone	GO:0033574	55	0.012
regulation of phagocytosis engulfment	GO:0060099	4	0.012
regulation of blood vessel size	GO:0050880	89	0.011
regulation of cellular component movement	GO:0051270	150	0.011
actin mediated cell contraction	GO:0070252	12	0.011
heart process	GO:0003015	57	0.011
regulation of stem cell differentiation	GO:2000736	2	0.011
negative regulation of cell death	GO:0060548	229	0.011
sodium ion transmembrane transport	GO:0035725	67	0.011
nucleoside catabolic process	GO:0009164	126	0.011
cellular response to lipid	GO:0071396	201	0.011
cellular response to nitrogen compound	GO:1901699	210	0.011
negative regulation of response to stimulus	GO:0048585	155	0.011
heart development	GO:0007507	72	0.011
glucose homeostasis	GO:0042593	75	0.011
positive regulation of cell communication	GO:0010647	271	0.011
cell growth	GO:0016049	104	0.011
response to toxic substance	GO:0009636	133	0.011
regulation of reactive oxygen species biosynthetic process	GO:1903426	5	0.011
negative regulation of rna biosynthetic process	GO:1902679	118	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	153	0.011
positive regulation of cellular component movement	GO:0051272	102	0.011
amine metabolic process	GO:0009308	38	0.011
oxoacid metabolic process	GO:0043436	290	0.011
organic acid metabolic process	GO:0006082	292	0.011
neurotransmitter transport	GO:0006836	42	0.011
cellular response to lipopolysaccharide	GO:0071222	55	0.011
cellular response to molecule of bacterial origin	GO:0071219	56	0.011
regulation of insulin secretion	GO:0050796	65	0.011
cellular response to insulin stimulus	GO:0032869	81	0.011
response to ph	GO:0009268	27	0.011
positive regulation of catabolic process	GO:0009896	78	0.011
ras protein signal transduction	GO:0007265	29	0.010
negative regulation of macromolecule biosynthetic process	GO:0010558	148	0.010
muscle organ development	GO:0007517	50	0.010
negative regulation of rna metabolic process	GO:0051253	123	0.010
regulation of anatomical structure size	GO:0090066	135	0.010	Yeast
protein phosphorylation	GO:0006468	345	0.010
cytoplasmic transport	GO:0016482	115	0.010
regulation of locomotion	GO:0040012	148	0.010
regulation of neuron death	GO:1901214	115	0.010
carbohydrate derivative biosynthetic process	GO:1901137	124	0.010
cell adhesion	GO:0007155	110	0.010
purine nucleotide metabolic process	GO:0006163	229	0.010

Coro6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
inherited metabolic disorder	DOID:655	0.044
disease of metabolism	DOID:0014667	0.044
long qt syndrome	DOID:2843	0.035
cardiovascular system disease	DOID:1287	0.027
disease of anatomical entity	DOID:7	0.027
carbohydrate metabolic disorder	DOID:2978	0.026
nervous system disease	DOID:863	0.017
muscular disease	DOID:0080000	0.013
musculoskeletal system disease	DOID:17	0.013

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