IMP: Integrative Multi-species Prediction

Rattus norvegicus

0 known processes

Rnf222

ring finger protein 222

(Aliases: RGD1310573)

Entrez: 363627
RGD: 1310573
Ensembl: ENSRNOG00000022964
UniProtKB: D3ZTZ3

Process Predictions
Disease Predictions

Rnf222 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
single organism reproductive process	GO:0044702	297	0.222
regulation of cellular protein metabolic process	GO:0032268	267	0.119
intracellular signal transduction	GO:0035556	314	0.093
response to extracellular stimulus	GO:0009991	380	0.087
regulation of molecular function	GO:0065009	398	0.085
regulation of cellular localization	GO:0060341	263	0.082
homeostatic process	GO:0042592	331	0.070
positive regulation of signaling	GO:0023056	270	0.069
regulation of phosphate metabolic process	GO:0019220	349	0.068
tongue morphogenesis	GO:0043587	3	0.067
cellular calcium ion homeostasis	GO:0006874	160	0.066
programmed cell death	GO:0012501	392	0.065
multi organism reproductive process	GO:0044703	262	0.065
cellular divalent inorganic cation homeostasis	GO:0072503	162	0.062
regulation of protein metabolic process	GO:0051246	289	0.061
cellular ion homeostasis	GO:0006873	184	0.058
regulation of phosphorus metabolic process	GO:0051174	349	0.057
tissue development	GO:0009888	252	0.055
cation transport	GO:0006812	382	0.055
divalent inorganic cation homeostasis	GO:0072507	165	0.055
response to nutrient levels	GO:0031667	370	0.054
cation homeostasis	GO:0055080	195	0.054
negative regulation of cell death	GO:0060548	229	0.054
protein complex biogenesis	GO:0070271	263	0.054
positive regulation of response to stimulus	GO:0048584	285	0.052
cellular metal ion homeostasis	GO:0006875	172	0.051
calcium ion homeostasis	GO:0055074	162	0.050
apoptotic process	GO:0006915	381	0.050
cellular component assembly	GO:0022607	360	0.050
macromolecular complex assembly	GO:0065003	273	0.049
negative regulation of metabolic process	GO:0009892	331	0.048
reproduction	GO:0000003	245	0.047
regulation of cell proliferation	GO:0042127	359	0.047
regulation of cellular component organization	GO:0051128	368	0.046
regulation of secretion	GO:0051046	224	0.046
aging	GO:0007568	241	0.045
cellular homeostasis	GO:0019725	252	0.044
multi multicellular organism process	GO:0044706	138	0.044
cytosolic calcium ion homeostasis	GO:0051480	140	0.044
lipid metabolic process	GO:0006629	283	0.044
response to inorganic substance	GO:0010035	377	0.043
response to other organism	GO:0051707	220	0.043
metal ion homeostasis	GO:0055065	186	0.043
multicellular organism reproduction	GO:0032504	233	0.042
reproductive process	GO:0022414	372	0.042
organelle organization	GO:0006996	266	0.041
cellular component biogenesis	GO:0044085	368	0.041
regulation of response to external stimulus	GO:0032101	106	0.041
regulation of cellular amine metabolic process	GO:0033238	8	0.040
regulation of body fluid levels	GO:0050878	90	0.040
cellular cation homeostasis	GO:0030003	180	0.040
regulation of secretion by cell	GO:1903530	208	0.038
cell projection organization	GO:0030030	302	0.038
multicellular organismal reproductive process	GO:0048609	233	0.038
macromolecule localization	GO:0033036	252	0.038
regulation of catalytic activity	GO:0050790	304	0.037
reproductive system development	GO:0061458	128	0.037
secretion by cell	GO:0032940	248	0.036
protein complex assembly	GO:0006461	263	0.036
macromolecular complex subunit organization	GO:0043933	339	0.036
positive regulation of cell proliferation	GO:0008284	249	0.035
cellular chemical homeostasis	GO:0055082	247	0.035
positive regulation of nitrogen compound metabolic process	GO:0051173	334	0.035
negative regulation of programmed cell death	GO:0043069	183	0.035
response to nutrient	GO:0007584	248	0.035
amine metabolic process	GO:0009308	38	0.034
response to glucocorticoid	GO:0051384	223	0.033
protein complex subunit organization	GO:0071822	302	0.032
proteolysis	GO:0006508	175	0.032
metal ion transport	GO:0030001	289	0.032
ion homeostasis	GO:0050801	212	0.031
positive regulation of protein metabolic process	GO:0051247	178	0.031
cellular response to oxygen containing compound	GO:1901701	386	0.031
response to hypoxia	GO:0001666	231	0.030
regulation of multicellular organismal development	GO:2000026	376	0.030
calcium ion transport	GO:0006816	131	0.030
protein oligomerization	GO:0051259	191	0.030
protein phosphorylation	GO:0006468	345	0.030
positive regulation of multicellular organismal process	GO:0051240	387	0.030
biological adhesion	GO:0022610	110	0.030
regulation of protein phosphorylation	GO:0001932	183	0.030
response to oxidative stress	GO:0006979	186	0.030
negative regulation of gene expression	GO:0010629	199	0.029
action potential	GO:0001508	54	0.029
regulation of ion transport	GO:0043269	245	0.029
wound healing	GO:0042060	122	0.029
regulation of response to stress	GO:0080134	126	0.028
neuron differentiation	GO:0030182	368	0.028
divalent inorganic cation transport	GO:0072511	134	0.028
g protein coupled receptor signaling pathway	GO:0007186	242	0.027
oxoacid metabolic process	GO:0043436	290	0.027
regulation of cellular amino acid metabolic process	GO:0006521	2	0.026
regulation of cell differentiation	GO:0045595	320	0.026
secretion	GO:0046903	307	0.026
positive regulation of molecular function	GO:0044093	230	0.026
regulation of hormone levels	GO:0010817	187	0.026
response to lipopolysaccharide	GO:0032496	191	0.025
chemical homeostasis	GO:0048878	292	0.025
gamete generation	GO:0007276	124	0.025
rna biosynthetic process	GO:0032774	380	0.025
regulation of protein modification process	GO:0031399	194	0.025
male sex differentiation	GO:0046661	64	0.025
response to biotic stimulus	GO:0009607	226	0.024
regulation of neuron differentiation	GO:0045664	208	0.024
regulation of hydrolase activity	GO:0051336	143	0.024
cellular amine metabolic process	GO:0044106	38	0.024
negative regulation of cellular metabolic process	GO:0031324	281	0.024
positive regulation of cell communication	GO:0010647	271	0.024
positive regulation of phosphate metabolic process	GO:0045937	262	0.023
response to wounding	GO:0009611	254	0.023
nucleotide metabolic process	GO:0009117	279	0.023
single organism organelle organization	GO:1902589	180	0.023
regulation of programmed cell death	GO:0043067	341	0.022
positive regulation of secretion by cell	GO:1903532	128	0.022
negative regulation of cell communication	GO:0010648	158	0.022
protein processing	GO:0016485	68	0.022
regulation of signal transduction	GO:0009966	318	0.022
organ regeneration	GO:0031100	101	0.021
negative regulation of apoptotic process	GO:0043066	181	0.021
response to external biotic stimulus	GO:0043207	221	0.021
organic cyclic compound catabolic process	GO:1901361	175	0.021
regulation of apoptotic process	GO:0042981	335	0.021
positive regulation of programmed cell death	GO:0043068	157	0.020
male gonad development	GO:0008584	59	0.020
positive regulation of phosphorylation	GO:0042327	177	0.020
developmental process involved in reproduction	GO:0003006	159	0.020
carbohydrate derivative metabolic process	GO:1901135	346	0.019
nucleotide catabolic process	GO:0009166	139	0.019
negative regulation of molecular function	GO:0044092	133	0.019
defense response	GO:0006952	194	0.019
heart morphogenesis	GO:0003007	3	0.019
circulatory system process	GO:0003013	183	0.019
response to acid chemical	GO:0001101	222	0.019
cellular response to stress	GO:0033554	269	0.019
positive regulation of protein phosphorylation	GO:0001934	135	0.019
regulation of cell development	GO:0060284	263	0.019
signal release	GO:0023061	145	0.019
wnt signaling pathway planar cell polarity pathway	GO:0060071	2	0.018
regulation of response to wounding	GO:1903034	69	0.018
cellular ketone metabolic process	GO:0042180	51	0.018
response to cytokine	GO:0034097	215	0.018
reproductive structure development	GO:0048608	128	0.018
response to oxygen levels	GO:0070482	265	0.018
negative regulation of transport	GO:0051051	136	0.017
negative regulation of protein metabolic process	GO:0051248	114	0.017
protein maturation	GO:0051604	68	0.017
positive regulation of catalytic activity	GO:0043085	184	0.017
regulation of peptide transport	GO:0090087	87	0.017
regulation of cellular ketone metabolic process	GO:0010565	27	0.017
transcription dna templated	GO:0006351	377	0.016
axis specification	GO:0009798	4	0.016
regeneration	GO:0031099	163	0.016
positive regulation of transport	GO:0051050	245	0.016
sexual reproduction	GO:0019953	148	0.016
positive regulation of cellular biosynthetic process	GO:0031328	295	0.016
nucleobase containing small molecule metabolic process	GO:0055086	316	0.016
response to decreased oxygen levels	GO:0036293	237	0.016
nucleobase containing compound catabolic process	GO:0034655	152	0.016
neurological system process involved in regulation of systemic arterial blood pressure	GO:0001976	3	0.016
cellular macromolecule localization	GO:0070727	122	0.016
regulation of phosphorylation	GO:0042325	248	0.016
cell adhesion	GO:0007155	110	0.016
negative regulation of multicellular organismal process	GO:0051241	203	0.016
nitrogen compound transport	GO:0071705	229	0.016
nucleoside catabolic process	GO:0009164	126	0.016
regulation of nervous system development	GO:0051960	264	0.016
neuron development	GO:0048666	286	0.016
single organism behavior	GO:0044708	130	0.016
cellular hormone metabolic process	GO:0034754	49	0.015
divalent metal ion transport	GO:0070838	132	0.015
purine containing compound metabolic process	GO:0072521	253	0.015
cell cell signaling	GO:0007267	335	0.015
spermatogenesis	GO:0007283	99	0.015
regulation of cell projection organization	GO:0031344	175	0.015
neuronal action potential	GO:0019228	35	0.015
negative regulation of signaling	GO:0023057	157	0.015
establishment of tissue polarity	GO:0007164	2	0.015
single organism biosynthetic process	GO:0044711	342	0.015
regulation of nucleic acid templated transcription	GO:1903506	380	0.015
protein localization	GO:0008104	191	0.015
negative regulation of macromolecule metabolic process	GO:0010605	260	0.014
cellular amino acid metabolic process	GO:0006520	107	0.014
negative regulation of response to stimulus	GO:0048585	155	0.014
regulation of intracellular signal transduction	GO:1902531	218	0.014
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	148	0.014
response to corticosteroid	GO:0031960	235	0.014
cellular nitrogen compound catabolic process	GO:0044270	163	0.014
nucleoside phosphate metabolic process	GO:0006753	283	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	247	0.014
neuron projection development	GO:0031175	273	0.014
cellular lipid metabolic process	GO:0044255	208	0.014
positive regulation of nucleobase containing compound metabolic process	GO:0045935	319	0.014
negative regulation of catalytic activity	GO:0043086	103	0.014
negative regulation of secretion	GO:0051048	82	0.014
positive regulation of cellular component organization	GO:0051130	200	0.014
positive regulation of developmental process	GO:0051094	283	0.014
transmission of nerve impulse	GO:0019226	42	0.014
nucleoside phosphate catabolic process	GO:1901292	140	0.014
development of primary male sexual characteristics	GO:0046546	59	0.014
carboxylic acid metabolic process	GO:0019752	289	0.014
response to peptide hormone	GO:0043434	278	0.014
positive regulation of biosynthetic process	GO:0009891	319	0.013
cellular response to lipid	GO:0071396	201	0.013
peptide transport	GO:0015833	97	0.013
regulation of protein processing	GO:0070613	50	0.013
positive regulation of protein modification process	GO:0031401	142	0.013
neurological system process	GO:0050877	219	0.013
response to alkaloid	GO:0043279	132	0.013
nucleoside metabolic process	GO:0009116	179	0.013
response to growth factor	GO:0070848	189	0.013
positive regulation of cellular protein metabolic process	GO:0032270	167	0.013
regulation of transferase activity	GO:0051338	123	0.013
morphogenesis of a polarized epithelium	GO:0001738	1	0.013
positive regulation of cellular amine metabolic process	GO:0033240	3	0.013
purine nucleotide metabolic process	GO:0006163	229	0.013
positive regulation of cell death	GO:0010942	184	0.013
positive regulation of cytosolic calcium ion concentration	GO:0007204	122	0.013
female pregnancy	GO:0007565	122	0.013
hormone secretion	GO:0046879	115	0.013
fibrinolysis	GO:0042730	2	0.013
transcription from rna polymerase ii promoter	GO:0006366	252	0.013
hormone metabolic process	GO:0042445	69	0.013
positive regulation of phosphorus metabolic process	GO:0010562	262	0.013
cellular response to endogenous stimulus	GO:0071495	377	0.012
cellular component morphogenesis	GO:0032989	155	0.012
gonad development	GO:0008406	104	0.012
positive regulation of signal transduction	GO:0009967	175	0.012
dna metabolic process	GO:0006259	96	0.012
metestrus	GO:0060210	1	0.012
response to bacterium	GO:0009617	200	0.012
male gamete generation	GO:0048232	99	0.012
purine ribonucleotide metabolic process	GO:0009150	227	0.012
organic acid metabolic process	GO:0006082	292	0.012
rhythmic process	GO:0048511	156	0.012
behavior	GO:0007610	205	0.012
ras protein signal transduction	GO:0007265	29	0.012
cytoplasmic transport	GO:0016482	115	0.012
sex differentiation	GO:0007548	113	0.012
positive regulation of cell projection organization	GO:0031346	111	0.012
aromatic compound catabolic process	GO:0019439	168	0.012
regulation of protein kinase activity	GO:0045859	105	0.012
ossification	GO:0001503	70	0.012
cellular protein localization	GO:0034613	122	0.012
male mating behavior	GO:0060179	3	0.012
anterior posterior pattern specification	GO:0009952	1	0.012
cell part morphogenesis	GO:0032990	123	0.012
coagulation	GO:0050817	28	0.011
actin cytoskeleton organization	GO:0030036	73	0.011
rna metabolic process	GO:0016070	406	0.011
response to metal ion	GO:0010038	253	0.011
response to reactive oxygen species	GO:0000302	120	0.011
response to molecule of bacterial origin	GO:0002237	194	0.011
negative regulation of fibrinolysis	GO:0051918	2	0.011
gliogenesis	GO:0042063	93	0.011
peptidyl amino acid modification	GO:0018193	126	0.011
positive regulation of neuron projection development	GO:0010976	99	0.011
defense response to gram negative bacterium	GO:0050829	3	0.011
organophosphate catabolic process	GO:0046434	148	0.011
cell motility	GO:0048870	202	0.011
cytoskeleton organization	GO:0007010	111	0.011
epithelial cell differentiation	GO:0030855	71	0.011
response to ketone	GO:1901654	182	0.011
regulation of rna metabolic process	GO:0051252	391	0.011
negative regulation of secretion by cell	GO:1903531	72	0.011
small gtpase mediated signal transduction	GO:0007264	36	0.011
sensory perception	GO:0007600	101	0.011
response to transition metal nanoparticle	GO:1990267	122	0.011
establishment of planar polarity	GO:0001736	1	0.011
transmembrane transport	GO:0055085	412	0.011
regulation of cell motility	GO:2000145	131	0.011
single organism catabolic process	GO:0044712	283	0.011
cofactor metabolic process	GO:0051186	95	0.011
glycosyl compound catabolic process	GO:1901658	126	0.010
nucleic acid templated transcription	GO:0097659	379	0.010
dendrite development	GO:0016358	72	0.010
response to estrogen	GO:0043627	232	0.010
purine nucleoside metabolic process	GO:0042278	169	0.010
regulation of rna biosynthetic process	GO:2001141	381	0.010
organic substance catabolic process	GO:1901575	316	0.010
regulation of proteolysis	GO:0030162	66	0.010
negative regulation of protein processing	GO:0010955	47	0.010
anatomical structure morphogenesis	GO:0009653	298	0.010
heterocycle catabolic process	GO:0046700	167	0.010
lymphocyte activation	GO:0046649	43	0.010
blood circulation	GO:0008015	183	0.010
response to radiation	GO:0009314	137	0.010
cellular response to corticosteroid stimulus	GO:0071384	69	0.010
embryonic axis specification	GO:0000578	1	0.010

Rnf222 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease	DO term ID	Probability
nervous system disease	DOID:863	0.017
disease of anatomical entity	DOID:7	0.017
urinary system disease	DOID:18	0.015

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