Rattus norvegicus

122 known processes

Drd4

dopamine receptor D4

(Aliases: D4RA)

Drd4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
inorganic ion transmembrane transportGO:00986602290.306
Human Rat
inorganic cation transmembrane transportGO:00986622020.209
Human Rat
regulation of ion transportGO:00432692450.193
Human Rat
cell projection organizationGO:00300303020.161
neuron differentiationGO:00301823680.157
Zebrafish
regulation of secretion by cellGO:19035302080.157
neurological system processGO:00508772190.142
regulation of intracellular signal transductionGO:19025312180.136
g protein coupled receptor signaling pathwayGO:00071862420.134
positive regulation of cell proliferationGO:00082842490.132
Rat
vesicle mediated transportGO:00161921810.122
Rat
cell morphogenesis involved in differentiationGO:00009041190.110
neuron projection developmentGO:00311752730.109
cation transportGO:00068123820.105
Human Rat
regulation of synaptic transmissionGO:00508041410.101
neuron developmentGO:00486662860.097
cgmp biosynthetic processGO:0006182150.096
axon developmentGO:0061564960.095
homeostatic processGO:00425923310.094
Rat
intracellular signal transductionGO:00355563140.094
cell cell signalingGO:00072673350.092
transmembrane transportGO:00550854120.089
Human Rat
nucleotide metabolic processGO:00091172790.088
Human Rat
negative regulation of nitrogen compound metabolic processGO:00511721610.084
Human Rat
synaptic transmissionGO:00072682350.083
regulation of neuron projection developmentGO:00109751610.082
negative regulation of cellular metabolic processGO:00313242810.082
Human Rat
negative regulation of metabolic processGO:00098923310.082
Human Rat
regulation of multicellular organismal developmentGO:20000263760.081
positive regulation of transportGO:00510502450.080
Human Rat
protein complex assemblyGO:00064612630.079
cell morphogenesis involved in neuron differentiationGO:00486671060.079
cellular ion homeostasisGO:00068731840.077
Rat
developmental process involved in reproductionGO:00030061590.075
regulation of cellular component organizationGO:00511283680.075
Rat
cellular homeostasisGO:00197252520.073
Rat
divalent inorganic cation homeostasisGO:00725071650.073
Rat
behaviorGO:00076102050.072
action potentialGO:0001508540.071
negative regulation of macromolecule metabolic processGO:00106052600.070
Rat
rhythmic processGO:00485111560.067
monovalent inorganic cation transportGO:00156721720.066
Human Rat
regulation of molecular functionGO:00650093980.065
Human Rat
cell projection morphogenesisGO:00488581230.064
lipid metabolic processGO:00066292830.063
Rat
anatomical structure morphogenesisGO:00096532980.062
regulation of nervous system developmentGO:00519602640.059
regulation of cell projection organizationGO:00313441750.057
eye morphogenesisGO:004859240.057
cellular component movementGO:00069282480.056
regulation of phosphate metabolic processGO:00192203490.056
Human Rat
heart morphogenesisGO:000300730.056
carbohydrate derivative metabolic processGO:19011353460.056
Human Rat
organophosphate metabolic processGO:00196373700.055
Human Rat
chemical homeostasisGO:00488782920.055
Rat
negative regulation of multicellular organismal processGO:00512412030.055
Rat
locomotionGO:00400112370.054
Rat
heart developmentGO:0007507720.053
regulation of phosphorus metabolic processGO:00511743490.053
Human Rat
regulation of neurogenesisGO:00507672470.052
negative regulation of signalingGO:00230571570.052
Rat
calcium ion homeostasisGO:00550741620.051
Rat
ion transmembrane transportGO:00342203650.050
Human Rat
cell morphogenesisGO:00009021420.048
regulation of neuron differentiationGO:00456642080.047
transmission of nerve impulseGO:0019226420.047
cellular response to stressGO:00335542690.045
ribose phosphate metabolic processGO:00196932350.045
Human Rat
macromolecular complex assemblyGO:00650032730.044
regulation of signal transductionGO:00099663180.044
positive regulation of signalingGO:00230562700.044
Human Rat
negative regulation of transportGO:00510511360.043
Human Rat
negative regulation of cell proliferationGO:00082851190.043
muscle contractionGO:0006936880.043
kidney developmentGO:0001822670.043
blood circulationGO:00080151830.042
nucleic acid templated transcriptionGO:00976593790.042
Rat
response to biotic stimulusGO:00096072260.041
negative regulation of cell communicationGO:00106481580.041
Rat
metal ion transportGO:00300012890.041
Human Rat
organelle organizationGO:00069962660.041
Rat
cellular component biogenesisGO:00440853680.040
Rat
calcium ion transportGO:00068161310.040
Human Rat
negative regulation of gene expressionGO:00106291990.040
Rat
mapk cascadeGO:00001651400.040
Human Rat
rna metabolic processGO:00160704060.040
Rat
response to ethanolGO:00454711620.039
Rat
motor neuron axon guidanceGO:000804510.038
acid secretionGO:0046717480.038
Human Rat
regulation of cell proliferationGO:00421273590.038
Rat
cellular response to endogenous stimulusGO:00714953770.038
neuron projection morphogenesisGO:00488121220.037
regulation of cellular localizationGO:00603412630.037
positive regulation of multicellular organismal processGO:00512403870.037
regulation of hormone levelsGO:00108171870.037
Rat
axis specificationGO:000979840.037
neuronal action potentialGO:0019228350.036
dendritic spine morphogenesisGO:006099790.036
cellular metal ion homeostasisGO:00068751720.036
Rat
cellular chemical homeostasisGO:00550822470.035
Rat
macromolecule localizationGO:00330362520.035
Human
protein oligomerizationGO:00512591910.035
circadian rhythmGO:0007623880.035
cation transmembrane transportGO:00986552630.035
Human Rat
tissue developmentGO:00098882520.035
single organism behaviorGO:00447081300.035
neuron neuron synaptic transmissionGO:0007270600.035
head developmentGO:00603222470.035
Rat
inflammatory responseGO:00069541500.035
retina morphogenesis in camera type eyeGO:006004210.035
regulation of cell developmentGO:00602842630.034
response to other organismGO:00517072200.034
cytosolic calcium ion homeostasisGO:00514801400.033
Rat
cellular component morphogenesisGO:00329891550.033
positive regulation of response to stimulusGO:00485842850.032
Human Rat
potassium ion transportGO:0006813970.032
Rat
amide biosynthetic processGO:0043604100.032
response to woundingGO:00096112540.032
Rat
secretionGO:00469033070.032
regulation of transmembrane transportGO:00347621220.031
Human Rat
cellular response to lipidGO:00713962010.031
cation homeostasisGO:00550801950.031
Rat
positive regulation of secretion by cellGO:19035321280.031
regulation of membrane potentialGO:00423911100.031
negative regulation of macromolecule biosynthetic processGO:00105581480.030
Rat
positive regulation of cytosolic calcium ion concentrationGO:00072041220.030
Rat
heart processGO:0003015570.030
positive regulation of biosynthetic processGO:00098913190.030
Rat
cellular amide metabolic processGO:0043603440.030
anion transportGO:00068201780.030
Human
cardiac muscle contractionGO:0060048270.030
multi multicellular organism processGO:00447061380.030
multicellular organismal signalingGO:0035637440.029
sensory perceptionGO:00076001010.029
regulation of transporter activityGO:0032409500.029
Human Rat
reproductive processGO:00224143720.029
metal ion homeostasisGO:00550651860.029
Rat
cellular response to nitrogen compoundGO:19016992100.028
response to external biotic stimulusGO:00432072210.028
vitamin d receptor signaling pathwayGO:007056110.028
steroid metabolic processGO:0008202730.028
reproductive system developmentGO:00614581280.028
regulation of ion transmembrane transportGO:00347651210.028
Human Rat
central nervous system developmentGO:00074173110.028
Zebrafish Rat
negative regulation of nervous system developmentGO:0051961790.027
response to extracellular stimulusGO:00099913800.027
jak stat cascadeGO:0007259260.027
cognitionGO:0050890920.027
regulation of lipid metabolic processGO:0019216680.027
agingGO:00075682410.026
ion homeostasisGO:00508012120.026
Rat
organonitrogen compound biosynthetic processGO:19015661670.026
Human Rat
detection of temperature stimulus involved in sensory perception of painGO:005096540.026
defense responseGO:00069521940.026
single organism biosynthetic processGO:00447113420.026
Human Rat
response to nutrient levelsGO:00316673700.026
purine nucleotide metabolic processGO:00061632290.026
Human Rat
positive regulation of nucleobase containing compound metabolic processGO:00459353190.025
Rat
nucleobase containing small molecule metabolic processGO:00550863160.025
Human Rat
glutamate receptor signaling pathwayGO:0007215430.025
nitrogen compound transportGO:00717052290.025
Rat
cellular lipid metabolic processGO:00442552080.025
Rat
tissue morphogenesisGO:0048729220.025
chemotaxisGO:0006935660.025
positive regulation of intracellular signal transductionGO:19025331380.025
Human Rat
cellular calcium ion homeostasisGO:00068741600.024
Rat
positive regulation of cell communicationGO:00106472710.024
Human Rat
learningGO:0007612330.024
negative regulation of cell differentiationGO:0045596990.024
regulation of cellular amino acid metabolic processGO:000652120.024
multicellular organismal reproductive processGO:00486092330.024
nucleotide biosynthetic processGO:0009165980.024
Human Rat
positive regulation of phosphate metabolic processGO:00459372620.024
Human Rat
negative regulation of cellular component organizationGO:0051129830.023
regulation of system processGO:00440572080.023
Rat
negative regulation of natural killer cell mediated cytotoxicityGO:004595340.023
negative regulation of cell developmentGO:0010721820.022
organic anion transportGO:00157111320.022
Human
regulation of locomotionGO:00400121480.022
Rat
retinal ganglion cell axon guidanceGO:003129010.022
cell part morphogenesisGO:00329901230.022
response to ammonium ionGO:0060359710.022
Human Mouse Rat
detection of stimulusGO:0051606240.022
taxisGO:0042330670.022
reproductionGO:00000032450.021
hormone metabolic processGO:0042445690.021
regulation of cell differentiationGO:00455953200.021
protein complex biogenesisGO:00702712630.021
olfactory behaviorGO:004204820.021
cyclic purine nucleotide metabolic processGO:0052652620.021
Human Rat
negative regulation of natural killer cell mediated immunityGO:000271640.021
organophosphate biosynthetic processGO:00904071430.021
Human Rat
response to acid chemicalGO:00011012220.021
response to calcium ionGO:0051592590.021
phospholipid metabolic processGO:0006644610.021
Rat
negative regulation of cell deathGO:00605482290.021
brain developmentGO:00074202470.021
Rat
purine ribonucleotide metabolic processGO:00091502270.021
Human Rat
apoptotic processGO:00069153810.021
secretion by cellGO:00329402480.020
negative regulation of secretionGO:0051048820.020
Human Rat
cellular potassium ion transportGO:0071804720.020
negative regulation of biosynthetic processGO:00098901680.020
Human Rat
signal releaseGO:00230611450.020
response to radiationGO:00093141370.020
multi organism reproductive processGO:00447032620.020
regulation of anatomical structure sizeGO:00900661350.020
embryonic skeletal system morphogenesisGO:004870430.020
positive regulation of apoptotic processGO:00430651540.020
sex differentiationGO:00075481130.020
peptide secretionGO:0002790860.020
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.020
Rat
carbohydrate derivative biosynthetic processGO:19011371240.020
Human Rat
circulatory system developmentGO:00723591340.019
cellular response to organic cyclic compoundGO:00714072020.019
embryonic pattern specificationGO:000988010.019
cellular response to oxygen containing compoundGO:19017013860.019
potassium ion transmembrane transportGO:0071805710.019
regulation of purine nucleotide biosynthetic processGO:1900371460.019
Human Rat
striated muscle contractionGO:0006941440.019
negative regulation of rna biosynthetic processGO:19026791180.019
Rat
cell migrationGO:00164771970.019
regulation of catalytic activityGO:00507903040.019
Human Rat
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169850.019
intracellular transportGO:00469071850.019
Rat
regulation of tube sizeGO:0035150890.019
skeletal system developmentGO:0001501410.019
purine nucleotide biosynthetic processGO:0006164830.019
Human Rat
reproductive structure developmentGO:00486081280.019
response to estradiolGO:00323551640.019
regulation of nucleotide biosynthetic processGO:0030808470.019
Human Rat
negative regulation of transporter activityGO:0032410130.019
Human Rat
regulation of circadian sleep wake cycleGO:0042749180.018
Rat
cellular cation homeostasisGO:00300031800.018
Rat
camera type eye morphogenesisGO:004859320.018
peptide biosynthetic processGO:004304330.018
camp metabolic processGO:0046058630.018
Human Rat
multicellular organism reproductionGO:00325042330.018
positive regulation of neurogenesisGO:00507691650.018
negative regulation of transcription dna templatedGO:00458921160.018
Rat
myelinationGO:0042552390.018
regulation of blood circulationGO:19035221100.018
cellular ketone metabolic processGO:0042180510.018
regulation of secretionGO:00510462240.018
dendrite developmentGO:0016358720.018
vitamin a metabolic processGO:000677620.018
ossificationGO:0001503700.018
macromolecular complex subunit organizationGO:00439333390.017
negative regulation of signal transductionGO:0009968830.017
Rat
positive regulation of cell projection organizationGO:00313461110.017
cellular response to abiotic stimulusGO:0071214850.017
negative regulation of nucleobase containing compound metabolic processGO:00459341530.017
Human Rat
neuronal stem cell maintenanceGO:009715020.017
negative regulation of secretion by cellGO:1903531720.017
Human Rat
alcohol metabolic processGO:0006066770.017
embryonic cranial skeleton morphogenesisGO:004870120.017
cellular response to vitamin eGO:007130630.017
regulation of synaptic plasticityGO:0048167700.017
Rat
cellular divalent inorganic cation homeostasisGO:00725031620.017
Rat
epithelial cell proliferationGO:0050673540.017
response to cytokineGO:00340972150.017
nucleoside phosphate metabolic processGO:00067532830.017
Human Rat
regulation of transmembrane transporter activityGO:0022898490.017
Human Rat
negative regulation of neuron differentiationGO:0045665620.017
regulation of protein metabolic processGO:00512462890.017
Human Rat
negative regulation of developmental processGO:00510931250.016
endocytosisGO:0006897840.016
Rat
response to inorganic substanceGO:00100353770.016
Rat
response to peptide hormoneGO:00434342780.016
developmental inductionGO:003112820.016
ribose phosphate biosynthetic processGO:0046390870.016
Human Rat
cardiac chamber developmentGO:000320510.016
purine ribonucleotide biosynthetic processGO:0009152810.016
Human Rat
urogenital system developmentGO:0001655780.016
regulation of rna metabolic processGO:00512523910.016
Rat
negative regulation of phosphate metabolic processGO:0045936800.016
Human Rat
regulation of glutamate receptor signaling pathwayGO:1900449170.016
positive regulation of developmental processGO:00510942830.016
response to peptideGO:19016522920.016
female pregnancyGO:00075651220.015
growthGO:00400071650.015
regulation of dendrite developmentGO:0050773590.015
second messenger mediated signalingGO:0019932510.015
negative regulation of response to stimulusGO:00485851550.015
Rat
membrane organizationGO:0061024940.015
localization of cellGO:00516742020.015
response to transition metal nanoparticleGO:19902671220.015
Rat
adult locomotory behaviorGO:000834440.015
Mouse
positive regulation of signal transductionGO:00099671750.015
Human Rat
response to nutrientGO:00075842480.015
forebrain developmentGO:0030900980.015
Rat
programmed cell deathGO:00125013920.015
cellular amine metabolic processGO:0044106380.015
Mouse
circadian behaviorGO:0048512240.015
Rat
camera type eye developmentGO:0043010480.015
regulation of transferase activityGO:00513381230.015
Human Rat
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.015
Rat
negative regulation of mitotic cell cycle phase transitionGO:190199130.014
positive regulation of cell developmentGO:00107201760.014
axonogenesisGO:0007409710.014
regulation of protein phosphorylationGO:00019321830.014
Human Rat
response to corticosteroidGO:00319602350.014
regulation of muscle system processGO:0090257790.014
regulation of apoptotic processGO:00429813350.014
cell motilityGO:00488702020.014
positive regulation of cellular component organizationGO:00511302000.014
Rat
nucleoside phosphate biosynthetic processGO:19012931020.014
Human Rat
cell cycle checkpointGO:000007520.014
calcium ion importGO:0070509220.014
regulation of smooth muscle cell proliferationGO:0048660750.014
negative regulation of rna metabolic processGO:00512531230.014
Rat
regulation of blood vessel sizeGO:0050880890.014
negative regulation of cell cycle phase transitionGO:190198840.014
connective tissue developmentGO:0061448330.014
cardiovascular system developmentGO:00723581340.014
response to estrogenGO:00436272320.014
response to retinoic acidGO:0032526630.014
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.013
Rat
regulation of metal ion transportGO:00109591180.013
Human Rat
positive regulation of ion transportGO:0043270940.013
Human
nucleobase containing compound catabolic processGO:00346551520.013
regulation of peptide hormone secretionGO:0090276800.013
Rat
enzyme linked receptor protein signaling pathwayGO:00071671160.013
regulation of mapk cascadeGO:00434081160.013
Human Rat
renal system developmentGO:0072001670.013
regulation of gluconeogenesisGO:000611140.013
positive regulation of cellular biosynthetic processGO:00313282950.013
Rat
embryonic skeletal system developmentGO:004870630.013
positive regulation of molecular functionGO:00440932300.013
Human Rat
protein complex subunit organizationGO:00718223020.013
striated muscle tissue developmentGO:0014706580.013
amine metabolic processGO:0009308380.013
Mouse
positive regulation of neuron projection developmentGO:0010976990.013
positive regulation of cellular amine metabolic processGO:003324030.013
synaptic vesicle endocytosisGO:004848840.013
ribonucleotide metabolic processGO:00092592310.013
Human Rat
cellular component assemblyGO:00226073600.013
Rat
dna metabolic processGO:0006259960.012
positive regulation of phosphorus metabolic processGO:00105622620.012
Human Rat
negative regulation of molecular functionGO:00440921330.012
Human Rat
negative regulation of phosphorylationGO:0042326570.012
response to growth factorGO:00708481890.012
negative regulation of protein metabolic processGO:00512481140.012
smooth muscle cell proliferationGO:0048659770.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
establishment of tissue polarityGO:000716420.012
regulation of purine nucleotide metabolic processGO:19005421150.012
Human Rat
positive regulation of secretionGO:00510471400.012
Rat
amine transportGO:0015837570.012
Rat
purine containing compound metabolic processGO:00725212530.012
Human Rat
regulation of programmed cell deathGO:00430673410.012
learning or memoryGO:0007611900.012
serotonin receptor signaling pathwayGO:0007210100.012
negative regulation of phosphorus metabolic processGO:0010563800.012
Human Rat
negative regulation of cellular protein metabolic processGO:00322691060.012
regulation of chromosome segregationGO:005198310.012
organ inductionGO:000175910.012
protein localizationGO:00081041910.012
Human
cellular response to fluid shear stressGO:007149840.012
axon ensheathmentGO:0008366400.012
organic acid transportGO:00158491160.012
Human
regulation of cellular ketone metabolic processGO:0010565270.011
positive regulation of nervous system developmentGO:00519621780.011
bmp signaling pathwayGO:003050940.011
organ morphogenesisGO:0009887750.011
peptide transportGO:0015833970.011
Rat
regulation of ion transmembrane transporter activityGO:0032412480.011
Human Rat
muscle cell apoptotic processGO:0010657300.011
morphogenesis of embryonic epitheliumGO:001633130.011
negative regulation of smooth muscle cell proliferationGO:0048662210.011
calcium ion transmembrane transportGO:0070588700.011
Human Rat
dendrite morphogenesisGO:0048813430.011
regulation of behaviorGO:0050795610.011
Rat
circulatory system processGO:00030131830.011
ensheathment of neuronsGO:0007272400.011
positive regulation of hepatocyte differentiationGO:007036820.011
regulation of phosphatidylinositol dephosphorylationGO:006030410.011
regulation of response to stressGO:00801341260.011
single organism membrane organizationGO:0044802740.011
male gamete generationGO:0048232990.011
positive regulation of cell differentiationGO:00455972170.011
catabolic processGO:00090563510.011
regulation of cellular amine metabolic processGO:003323880.011
Mouse
positive regulation of epithelial cell proliferationGO:0050679320.011
morphogenesis of a polarized epitheliumGO:000173810.011
insulin like growth factor receptor signaling pathwayGO:004800930.011
small gtpase mediated signal transductionGO:0007264360.011
locomotor rhythmGO:004547510.011
retina development in camera type eyeGO:0060041270.011
pancreatic stellate cell proliferationGO:007234320.011
purine ribonucleoside triphosphate catabolic processGO:00092071220.011
positive regulation of cell deathGO:00109421840.011
regulation of cellular component movementGO:00512701500.011
response to metal ionGO:00100382530.010
Rat
cellular response to organonitrogen compoundGO:00714171970.010
regulation of organ formationGO:000315620.010
regulation of hormone secretionGO:00468831060.010
Rat
salivary gland developmentGO:000743130.010
glycosyl compound catabolic processGO:19016581260.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
cellular macromolecule localizationGO:00707271220.010
neuropeptide signaling pathwayGO:0007218290.010
neurotransmitter secretionGO:0007269330.010
muscle organ morphogenesisGO:004864410.010
negative regulation of cellular biosynthetic processGO:00313271610.010
Human Rat
protein heterooligomerizationGO:0051291890.010
embryonic axis specificationGO:000057810.010
regulation of rna biosynthetic processGO:20011413810.010
Rat
morphogenesis of an epitheliumGO:0002009200.010
response to insulinGO:00328681330.010
cellular catabolic processGO:00442482950.010

Drd4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.364
nervous system diseaseDOID:86300.364
sensory system diseaseDOID:005015500.139
eye and adnexa diseaseDOID:149200.139
eye diseaseDOID:561400.139
muscle tissue diseaseDOID:6600.064
muscular diseaseDOID:008000000.064
musculoskeletal system diseaseDOID:1700.064
retinal diseaseDOID:567900.036
retinal degenerationDOID:846600.036
night blindnessDOID:849900.030
retinitis pigmentosaDOID:1058400.025
myopathyDOID:42300.024
central nervous system diseaseDOID:33100.021
cardiovascular system diseaseDOID:128700.020
bone diseaseDOID:008000100.013
connective tissue diseaseDOID:6500.013
osteochondrodysplasiaDOID:225600.013
bone development diseaseDOID:008000600.013
vascular diseaseDOID:17800.011
gastrointestinal system diseaseDOID:7700.011
neuropathyDOID:87000.010
neuromuscular diseaseDOID:44000.010