Rattus norvegicus

61 known processes

Hsd11b2

hydroxysteroid 11-beta dehydrogenase 2

(Aliases: MGC93528)

Hsd11b2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to carbohydrateGO:00097431830.117
cellular response to oxygen containing compoundGO:19017013860.111
response to monosaccharideGO:00342841590.110
neuron developmentGO:00486662860.091
negative regulation of multicellular organismal processGO:00512412030.089
cation homeostasisGO:00550801950.089
central nervous system developmentGO:00074173110.081
Rat
carboxylic acid metabolic processGO:00197522890.081
Rat
anatomical structure morphogenesisGO:00096532980.071
tissue developmentGO:00098882520.069
Rat
cellular homeostasisGO:00197252520.069
chemical homeostasisGO:00488782920.069
rna biosynthetic processGO:00327743800.069
neuron projection developmentGO:00311752730.068
oxoacid metabolic processGO:00434362900.067
Rat
cell projection organizationGO:00300303020.067
regulation of cell differentiationGO:00455953200.066
regulation of molecular functionGO:00650093980.066
epithelium developmentGO:0060429960.065
enzyme linked receptor protein signaling pathwayGO:00071671160.060
metal ion homeostasisGO:00550651860.060
positive regulation of nucleobase containing compound metabolic processGO:00459353190.060
cellular response to organonitrogen compoundGO:00714171970.060
neuron differentiationGO:00301823680.060
cell motilityGO:00488702020.059
cellular chemical homeostasisGO:00550822470.058
regulation of cell projection organizationGO:00313441750.058
nitrogen compound transportGO:00717052290.056
positive regulation of cellular biosynthetic processGO:00313282950.055
cellular amino acid metabolic processGO:00065201070.055
positive regulation of nitrogen compound metabolic processGO:00511733340.054
regulation of transcription dna templatedGO:00063553740.054
response to growth factorGO:00708481890.053
cellular response to nitrogen compoundGO:19016992100.051
locomotionGO:00400112370.050
positive regulation of biosynthetic processGO:00098913190.049
regulation of cell proliferationGO:00421273590.048
brain developmentGO:00074202470.048
Rat
alpha amino acid metabolic processGO:1901605710.046
single organism carbohydrate metabolic processGO:00447231180.046
organophosphate metabolic processGO:00196373700.046
cell projection morphogenesisGO:00488581230.045
organic acid metabolic processGO:00060822920.045
Rat
rna metabolic processGO:00160704060.044
response to peptideGO:19016522920.043
calcium ion transportGO:00068161310.043
cellular response to growth factor stimulusGO:00713631620.043
positive regulation of response to stimulusGO:00485842850.043
response to glucoseGO:00097491360.042
nucleic acid templated transcriptionGO:00976593790.041
response to nutrient levelsGO:00316673700.041
transmembrane transportGO:00550854120.041
localization of cellGO:00516742020.040
regulation of programmed cell deathGO:00430673410.040
cellular response to hormone stimulusGO:00328702470.040
cellular component biogenesisGO:00440853680.040
response to inorganic substanceGO:00100353770.040
Rat
programmed cell deathGO:00125013920.039
positive regulation of rna metabolic processGO:00512542030.038
regulation of cellular component organizationGO:00511283680.038
positive regulation of gene expressionGO:00106282440.038
regulation of rna metabolic processGO:00512523910.037
transcription dna templatedGO:00063513770.037
cellular component movementGO:00069282480.037
regulation of nervous system developmentGO:00519602640.037
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.036
regulation of signal transductionGO:00099663180.036
positive regulation of macromolecule biosynthetic processGO:00105572470.035
ion homeostasisGO:00508012120.035
cellular metal ion homeostasisGO:00068751720.034
carbohydrate derivative metabolic processGO:19011353460.034
macromolecular complex assemblyGO:00650032730.034
apoptotic processGO:00069153810.034
response to acid chemicalGO:00011012220.034
negative regulation of developmental processGO:00510931250.033
homeostatic processGO:00425923310.033
cellular divalent inorganic cation homeostasisGO:00725031620.033
regulation of multicellular organismal developmentGO:20000263760.033
cell migrationGO:00164771970.032
response to hexoseGO:00097461440.032
catabolic processGO:00090563510.032
head developmentGO:00603222470.032
Rat
amine metabolic processGO:0009308380.031
regulation of rna biosynthetic processGO:20011413810.031
single organism biosynthetic processGO:00447113420.031
Rat
divalent inorganic cation homeostasisGO:00725071650.030
regulation of nucleic acid templated transcriptionGO:19035063800.030
proteolysisGO:00065081750.030
cell morphogenesisGO:00009021420.030
positive regulation of transportGO:00510502450.030
regulation of catalytic activityGO:00507903040.029
cellular response to organic cyclic compoundGO:00714072020.029
regulation of neurogenesisGO:00507672470.029
negative regulation of nucleic acid templated transcriptionGO:19035071170.029
purine containing compound metabolic processGO:00725212530.029
neurological system processGO:00508772190.029
carbohydrate metabolic processGO:00059751300.029
reproductive structure developmentGO:00486081280.029
divalent inorganic cation transportGO:00725111340.029
regulation of cell developmentGO:00602842630.028
divalent metal ion transportGO:00708381320.028
reproductionGO:00000032450.028
positive regulation of rna biosynthetic processGO:19026801970.028
defense responseGO:00069521940.028
regulation of cellular ketone metabolic processGO:0010565270.028
response to hypoxiaGO:00016662310.028
positive regulation of nucleic acid templated transcriptionGO:19035081970.028
regulation of apoptotic processGO:00429813350.027
response to nutrientGO:00075842480.027
Rat
cellular response to lipidGO:00713962010.027
regulation of ion transportGO:00432692450.026
cellular component assemblyGO:00226073600.026
cellular response to peptideGO:19016531330.026
carbohydrate homeostasisGO:0033500750.026
ribose phosphate metabolic processGO:00196932350.026
negative regulation of cellular biosynthetic processGO:00313271610.025
cell part morphogenesisGO:00329901230.025
response to decreased oxygen levelsGO:00362932370.025
response to glucocorticoidGO:00513842230.025
response to mineralocorticoidGO:0051385490.025
Rat
organophosphate biosynthetic processGO:00904071430.025
cell cell signalingGO:00072673350.025
cellular response to fluid shear stressGO:007149840.025
response to metal ionGO:00100382530.025
Rat
metal ion transportGO:00300012890.024
multicellular organism growthGO:003526410.024
nucleotide metabolic processGO:00091172790.024
negative regulation of gene expressionGO:00106291990.024
cellular ketone metabolic processGO:0042180510.024
calcium ion homeostasisGO:00550741620.024
regulation of neuron projection developmentGO:00109751610.024
immune responseGO:00069551040.023
regulation of neuron differentiationGO:00456642080.023
g protein coupled receptor signaling pathwayGO:00071862420.023
positive regulation of cellular component organizationGO:00511302000.023
regulation of phosphate metabolic processGO:00192203490.023
negative regulation of rna biosynthetic processGO:19026791180.023
agingGO:00075682410.023
intracellular transportGO:00469071850.023
cellular calcium ion homeostasisGO:00068741600.023
cellular response to stressGO:00335542690.023
regulation of cellular amine metabolic processGO:003323880.023
protein phosphorylationGO:00064683450.022
endocytosisGO:0006897840.022
epibolyGO:009050420.022
regulation of hormone secretionGO:00468831060.022
regulation of protein modification processGO:00313991940.022
response to peptide hormoneGO:00434342780.022
vesicle mediated transportGO:00161921810.022
negative regulation of rna metabolic processGO:00512531230.022
cellular response to peptide hormone stimulusGO:00713751200.022
nucleobase containing small molecule metabolic processGO:00550863160.021
small molecule biosynthetic processGO:00442831240.021
Rat
multi organism reproductive processGO:00447032620.021
negative regulation of macromolecule biosynthetic processGO:00105581480.021
cellular catabolic processGO:00442482950.021
response to oxygen levelsGO:00704822650.021
dna metabolic processGO:0006259960.021
transcription from rna polymerase ii promoterGO:00063662520.021
regulation of hormone levelsGO:00108171870.021
Rat
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.021
protein complex assemblyGO:00064612630.021
single organism catabolic processGO:00447122830.020
regulation of phosphorus metabolic processGO:00511743490.020
regulation of calcium ion transportGO:0051924770.020
nucleoside phosphate metabolic processGO:00067532830.020
multicellular organism reproductionGO:00325042330.020
regulation of cellular amino acid metabolic processGO:000652120.020
protein localizationGO:00081041910.020
cellular response to endogenous stimulusGO:00714953770.020
protein complex biogenesisGO:00702712630.020
positive regulation of phosphorus metabolic processGO:00105622620.020
organic substance catabolic processGO:19015753160.019
growthGO:00400071650.019
peptide secretionGO:0002790860.019
cellular amine metabolic processGO:0044106380.019
negative regulation of transcription dna templatedGO:00458921160.019
developmental process involved in reproductionGO:00030061590.019
macromolecular complex subunit organizationGO:00439333390.019
male mating behaviorGO:006017930.019
protein complex subunit organizationGO:00718223020.019
cation transportGO:00068123820.018
response to extracellular stimulusGO:00099913800.018
response to campGO:0051591910.018
cell morphogenesis involved in differentiationGO:00009041190.018
positive regulation of cytosolic calcium ion concentrationGO:00072041220.018
response to vitaminGO:00332731310.018
positive regulation of developmental processGO:00510942830.018
cell morphogenesis involved in neuron differentiationGO:00486671060.018
response to organophosphorusGO:00466831020.018
negative regulation of macromolecule metabolic processGO:00106052600.018
cellular component morphogenesisGO:00329891550.018
cellular cation homeostasisGO:00300031800.018
development of primary sexual characteristicsGO:00451371070.018
neuron deathGO:00709971270.018
cellular response to cytokine stimulusGO:00713451270.018
negative regulation of nucleobase containing compound metabolic processGO:00459341530.018
sexual reproductionGO:00199531480.018
positive regulation of molecular functionGO:00440932300.017
behaviorGO:00076102050.017
positive regulation of protein modification processGO:00314011420.017
response to toxic substanceGO:00096361330.017
Rat
regulation of protein metabolic processGO:00512462890.017
positive regulation of ion transportGO:0043270940.017
single organism reproductive processGO:00447022970.017
positive regulation of protein metabolic processGO:00512471780.017
regulation of secretionGO:00510462240.017
negative regulation of response to stimulusGO:00485851550.017
regulation of metal ion transportGO:00109591180.017
positive regulation of nervous system developmentGO:00519621780.017
hormone transportGO:00099141210.017
cellular macromolecule localizationGO:00707271220.016
glucose homeostasisGO:0042593750.016
tongue morphogenesisGO:004358730.016
inflammatory responseGO:00069541500.016
cytosolic calcium ion homeostasisGO:00514801400.016
ion transmembrane transportGO:00342203650.016
organonitrogen compound biosynthetic processGO:19015661670.016
cellular amide metabolic processGO:0043603440.016
positive regulation of cell differentiationGO:00455972170.016
positive regulation of transcription dna templatedGO:00458931970.016
inorganic cation transmembrane transportGO:00986622020.016
carboxylic acid biosynthetic processGO:0046394830.016
Rat
gastrulationGO:000736920.016
negative regulation of programmed cell deathGO:00430691830.016
circulatory system developmentGO:00723591340.016
macromolecule localizationGO:00330362520.016
axon developmentGO:0061564960.015
muscle system processGO:00030121150.015
regulation of reactive oxygen species metabolic processGO:2000377260.015
membrane organizationGO:0061024940.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.015
negative regulation of metabolic processGO:00098923310.015
regulation of phosphorylationGO:00423252480.015
cell adhesionGO:00071551100.015
coenzyme metabolic processGO:0006732860.015
immune system processGO:00023762040.015
negative regulation of cell deathGO:00605482290.015
negative regulation of neuron differentiationGO:0045665620.015
sex differentiationGO:00075481130.015
male sex differentiationGO:0046661640.015
regulation of protein phosphorylationGO:00019321830.014
cellular ion homeostasisGO:00068731840.014
negative regulation of cellular metabolic processGO:00313242810.014
calcium ion transport into cytosolGO:0060402380.014
organic acid catabolic processGO:0016054490.014
chemotaxisGO:0006935660.014
inorganic ion transmembrane transportGO:00986602290.014
regulation of transferase activityGO:00513381230.014
regulation of system processGO:00440572080.014
reproductive system developmentGO:00614581280.014
intracellular signal transductionGO:00355563140.014
response to oxidative stressGO:00069791860.014
response to purine containing compoundGO:00140741260.014
response to amineGO:0014075460.014
cellular response to insulin stimulusGO:0032869810.014
wound healingGO:00420601220.014
negative regulation of cellular component organizationGO:0051129830.014
multi multicellular organism processGO:00447061380.013
sequestering of calcium ionGO:005120880.013
sequestering of metal ionGO:005123890.013
positive regulation of cellular amine metabolic processGO:003324030.013
cellular response to carbohydrate stimulusGO:0071322720.013
positive regulation of cell deathGO:00109421840.013
oxidation reduction processGO:00551143040.013
negative regulation of fibrinolysisGO:005191820.013
response to molecule of bacterial originGO:00022371940.013
gonad developmentGO:00084061040.012
positive regulation of cellular amino acid metabolic processGO:004576410.012
regulation of anatomical structure morphogenesisGO:00226031410.012
negative regulation of biosynthetic processGO:00098901680.012
response to ketoneGO:19016541820.012
Rat
reproductive processGO:00224143720.012
response to woundingGO:00096112540.012
peptide metabolic processGO:0006518320.012
establishment of tissue polarityGO:000716420.012
positive regulation of phosphate metabolic processGO:00459372620.012
regulation of cell morphogenesisGO:0022604770.012
regulation of anatomical structure sizeGO:00900661350.012
response to alkaloidGO:00432791320.012
cytoplasmic transportGO:00164821150.012
nucleoside monophosphate metabolic processGO:0009123930.012
regulation of neuron deathGO:19012141150.012
blood circulationGO:00080151830.012
cellular response to oxygen levelsGO:0071453600.012
cardiovascular system developmentGO:00723581340.012
ribonucleoside metabolic processGO:00091191740.012
protein heterooligomerizationGO:0051291890.012
multicellular organismal reproductive processGO:00486092330.012
carboxylic acid catabolic processGO:0046395490.012
reactive oxygen species metabolic processGO:0072593370.012
regulation of locomotionGO:00400121480.012
embryonic skeletal system developmentGO:004870630.012
positive regulation of catalytic activityGO:00430851840.012
developmental growthGO:00485891000.012
regulation of dna metabolic processGO:0051052600.012
telencephalon developmentGO:0021537620.012
epithelial cell differentiationGO:0030855710.012
response to electrical stimulusGO:0051602560.011
cofactor metabolic processGO:0051186950.011
muscle structure developmentGO:0061061870.011
regulation of canonical wnt signaling pathwayGO:006082840.011
synaptic transmissionGO:00072682350.011
single organism organelle organizationGO:19025891800.011
regulation of kinase activityGO:00435491170.011
ras protein signal transductionGO:0007265290.011
nucleoside metabolic processGO:00091161790.011
positive regulation of apoptotic processGO:00430651540.011
cellular response to steroid hormone stimulusGO:0071383930.011
response to activityGO:0014823730.011
negative regulation of nitrogen compound metabolic processGO:00511721610.011
positive regulation of programmed cell deathGO:00430681570.011
negative regulation of molecular functionGO:00440921330.011
negative regulation of apoptotic processGO:00430661810.011
regulation of proteasomal protein catabolic processGO:006113640.011
purine ribonucleotide metabolic processGO:00091502270.011
regulation of cellular protein metabolic processGO:00322682670.011
secretionGO:00469033070.011
negative regulation of cell developmentGO:0010721820.011
regulation of insulin secretionGO:0050796650.011
vascular process in circulatory systemGO:0003018960.011
secretion by cellGO:00329402480.011
multicellular organismal signalingGO:0035637440.011
vasodilationGO:0042311440.011
positive regulation of cell projection organizationGO:00313461110.011
positive regulation of protein phosphorylationGO:00019341350.011
circadian rhythmGO:0007623880.011
actin filament based movementGO:0030048160.011
cellular response to alcoholGO:0097306870.011
negative regulation of nervous system developmentGO:0051961790.011
positive regulation of hormone secretionGO:0046887650.011
positive regulation of neurogenesisGO:00507691650.011
cellular response to biotic stimulusGO:0071216590.011
regulation of neuron apoptotic processGO:0043523830.011
multicellular organismal water homeostasisGO:005089140.011
organic anion transportGO:00157111320.011
positive regulation of cellular protein metabolic processGO:00322701670.011
monocarboxylic acid metabolic processGO:00327871520.011
Rat
signal releaseGO:00230611450.011
cellular response to hexose stimulusGO:0071331650.011
spermatogenesisGO:0007283990.010
cellular lipid metabolic processGO:00442552080.010
Rat
formation of primary germ layerGO:000170410.010
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010120.010
cellular response to monosaccharide stimulusGO:0071326670.010
small molecule catabolic processGO:0044282590.010
regulation of intracellular signal transductionGO:19025312180.010
adult locomotory behaviorGO:000834440.010
negative regulation of transportGO:00510511360.010
organic acid biosynthetic processGO:0016053830.010
Rat
cell type specific apoptotic processGO:00972851340.010
cellular response to lipopolysaccharideGO:0071222550.010
circadian regulation of gene expressionGO:003292230.010
response to axon injuryGO:0048678590.010
cellular protein localizationGO:00346131220.010

Hsd11b2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.072
urinary system diseaseDOID:1800.072
kidney diseaseDOID:55700.063
disease of metabolismDOID:001466700.016
inherited metabolic disorderDOID:65500.016
musculoskeletal system diseaseDOID:1700.016
nervous system diseaseDOID:86300.013
disease of cellular proliferationDOID:1456600.012
respiratory system diseaseDOID:157900.011
lower respiratory tract diseaseDOID:005016100.011
connective tissue diseaseDOID:6500.011