Rattus norvegicus

135 known processes

Madd

MAP-kinase activating death domain

Madd biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular localizationGO:00603412630.169
macromolecule localizationGO:00330362520.164
neuron developmentGO:00486662860.162
cell projection organizationGO:00300303020.160
regulation of cellular component organizationGO:00511283680.155
neuron differentiationGO:00301823680.141
protein complex assemblyGO:00064612630.135
macromolecular complex subunit organizationGO:00439333390.130
macromolecular complex assemblyGO:00650032730.129
establishment of protein localizationGO:00451841410.125
neuron projection morphogenesisGO:00488121220.115
positive regulation of transportGO:00510502450.110
organonitrogen compound catabolic processGO:19015651790.107
Human
protein localizationGO:00081041910.100
regulation of vesicle mediated transportGO:0060627810.097
cellular component movementGO:00069282480.095
regulation of signal transductionGO:00099663180.093
regulation of secretion by cellGO:19035302080.093
regulation of apoptotic processGO:00429813350.093
Human
cell migrationGO:00164771970.086
vesicle mediated transportGO:00161921810.085
intracellular signal transductionGO:00355563140.085
Human
catabolic processGO:00090563510.084
Human
organelle organizationGO:00069962660.084
neuron projection developmentGO:00311752730.082
protein complex biogenesisGO:00702712630.081
regulation of molecular functionGO:00650093980.080
reproductive processGO:00224143720.079
regulation of protein kinase activityGO:00458591050.078
Human
axon developmentGO:0061564960.078
protein phosphorylationGO:00064683450.078
Human
regulation of neurogenesisGO:00507672470.077
positive regulation of phosphorus metabolic processGO:00105622620.076
protein transportGO:00150311320.076
cell cell signalingGO:00072673350.074
cellular component biogenesisGO:00440853680.074
cell projection morphogenesisGO:00488581230.073
regulation of programmed cell deathGO:00430673410.073
Human
establishment of vesicle localizationGO:0051650310.072
cell morphogenesis involved in neuron differentiationGO:00486671060.071
secretionGO:00469033070.070
cell morphogenesisGO:00009021420.067
negative regulation of gene expressionGO:00106291990.067
heterocycle catabolic processGO:00467001670.066
Human
synaptic vesicle localizationGO:0097479240.066
secretion by cellGO:00329402480.065
cellular component assemblyGO:00226073600.065
regulation of catalytic activityGO:00507903040.065
brain developmentGO:00074202470.064
apoptotic processGO:00069153810.064
Human
exocytosisGO:0006887600.063
transcription dna templatedGO:00063513770.063
regulation of multicellular organismal developmentGO:20000263760.063
negative regulation of macromolecule metabolic processGO:00106052600.063
locomotionGO:00400112370.062
organic substance catabolic processGO:19015753160.062
Human
synaptic transmissionGO:00072682350.061
localization of cellGO:00516742020.061
protein complex subunit organizationGO:00718223020.061
oxoacid metabolic processGO:00434362900.060
regulation of cell developmentGO:00602842630.059
positive regulation of catalytic activityGO:00430851840.059
cellular amino acid metabolic processGO:00065201070.059
purine ribonucleotide catabolic processGO:00091541360.059
Human
single organism reproductive processGO:00447022970.059
regulation of rna biosynthetic processGO:20011413810.059
regulation of cell migrationGO:00303341280.058
regulation of cell differentiationGO:00455953200.057
regulation of secretionGO:00510462240.056
positive regulation of nucleobase containing compound metabolic processGO:00459353190.055
negative regulation of metabolic processGO:00098923310.054
carbohydrate derivative metabolic processGO:19011353460.053
Human
programmed cell deathGO:00125013920.053
Human
regulation of nucleic acid templated transcriptionGO:19035063800.051
purine ribonucleoside catabolic processGO:00461301240.050
Human
negative regulation of cellular metabolic processGO:00313242810.050
positive regulation of gene expressionGO:00106282440.050
regulation of neuron projection developmentGO:00109751610.050
positive regulation of secretionGO:00510471400.049
reproductionGO:00000032450.049
regulation of protein transportGO:0051223680.048
negative regulation of nitrogen compound metabolic processGO:00511721610.047
negative regulation of cell deathGO:00605482290.047
head developmentGO:00603222470.046
single organism organelle organizationGO:19025891800.046
rna metabolic processGO:00160704060.046
endocytosisGO:0006897840.046
cellular protein localizationGO:00346131220.046
response to woundingGO:00096112540.045
central nervous system developmentGO:00074173110.045
intracellular transportGO:00469071850.045
positive regulation of nitrogen compound metabolic processGO:00511733340.044
cell morphogenesis involved in differentiationGO:00009041190.044
regulation of neuron differentiationGO:00456642080.043
purine containing compound catabolic processGO:00725231380.042
Human
nucleobase containing small molecule metabolic processGO:00550863160.042
Human
anatomical structure morphogenesisGO:00096532980.041
establishment of organelle localizationGO:0051656370.041
purine nucleotide catabolic processGO:00061951360.040
Human
regulation of phosphorus metabolic processGO:00511743490.040
cell motilityGO:00488702020.040
carboxylic acid metabolic processGO:00197522890.040
single organism intracellular transportGO:19025821660.040
ribonucleoside catabolic processGO:00424541260.040
Human
positive regulation of biosynthetic processGO:00098913190.039
purine ribonucleotide metabolic processGO:00091502270.038
Human
organic acid metabolic processGO:00060822920.038
nucleic acid templated transcriptionGO:00976593790.038
synaptic vesicle primingGO:001608240.038
regulation of transcription dna templatedGO:00063553740.038
regulation of transferase activityGO:00513381230.038
Human
ribose phosphate metabolic processGO:00196932350.037
Human
positive regulation of secretion by cellGO:19035321280.037
nucleoside metabolic processGO:00091161790.037
Human
multicellular organism reproductionGO:00325042330.036
regulation of protein modification processGO:00313991940.035
Human
response to extracellular stimulusGO:00099913800.035
neuron apoptotic processGO:0051402880.035
negative regulation of multicellular organismal processGO:00512412030.035
cell part morphogenesisGO:00329901230.035
regulation of protein phosphorylationGO:00019321830.034
Human
sexual reproductionGO:00199531480.034
protein oligomerizationGO:00512591910.034
positive regulation of phosphate metabolic processGO:00459372620.034
transcription from rna polymerase ii promoterGO:00063662520.033
cellular component morphogenesisGO:00329891550.033
regulation of kinase activityGO:00435491170.033
Human
protein autophosphorylationGO:0046777660.033
response to radiationGO:00093141370.033
rna biosynthetic processGO:00327743800.032
regulation of cellular protein metabolic processGO:00322682670.032
Human
purine ribonucleoside triphosphate metabolic processGO:00092051400.032
Human
cellular nitrogen compound catabolic processGO:00442701630.032
Human
positive regulation of macromolecule biosynthetic processGO:00105572470.032
aromatic compound catabolic processGO:00194391680.032
Human
glycosyl compound catabolic processGO:19016581260.032
Human
positive regulation of neurogenesisGO:00507691650.031
nucleoside triphosphate metabolic processGO:00091411440.031
Human
cellular response to stressGO:00335542690.031
cell adhesionGO:00071551100.031
regulation of phosphorylationGO:00423252480.031
Human
regulation of rna metabolic processGO:00512523910.031
signal releaseGO:00230611450.031
positive regulation of programmed cell deathGO:00430681570.031
regulation of hydrolase activityGO:00513361430.031
regulation of establishment of protein localizationGO:0070201690.030
regulation of phosphate metabolic processGO:00192203490.030
negative regulation of transcription dna templatedGO:00458921160.030
homeostatic processGO:00425923310.030
response to nutrient levelsGO:00316673700.030
multi organism reproductive processGO:00447032620.030
cellular response to oxygen containing compoundGO:19017013860.030
multicellular organismal reproductive processGO:00486092330.030
response to metal ionGO:00100382530.030
negative regulation of programmed cell deathGO:00430691830.030
response to peptide hormoneGO:00434342780.030
negative regulation of biosynthetic processGO:00098901680.030
purine nucleotide metabolic processGO:00061632290.030
Human
anterior posterior pattern specificationGO:000995210.030
regulation of protein metabolic processGO:00512462890.029
Human
intracellular protein transportGO:0006886790.029
cellular amine metabolic processGO:0044106380.029
regulation of nervous system developmentGO:00519602640.029
negative regulation of neuron differentiationGO:0045665620.029
response to cytokineGO:00340972150.029
regulation of exocytosisGO:0017157370.029
neurological system processGO:00508772190.028
regulation of cellular amine metabolic processGO:003323880.028
amine metabolic processGO:0009308380.028
gtp catabolic processGO:0006184710.028
Human
positive regulation of cell differentiationGO:00455972170.028
positive regulation of phosphorylationGO:00423271770.028
Human
vesicle localizationGO:0051648330.028
positive regulation of cellular component organizationGO:00511302000.028
peptidyl amino acid modificationGO:00181931260.028
positive regulation of cellular biosynthetic processGO:00313282950.028
organophosphate catabolic processGO:00464341480.027
Human
cellular catabolic processGO:00442482950.027
Human
single organism catabolic processGO:00447122830.027
Human
regulation of transcription from rna polymerase ii promoterGO:00063572340.027
response to hexoseGO:00097461440.027
membrane organizationGO:0061024940.027
gamete generationGO:00072761240.027
purine nucleoside metabolic processGO:00422781690.027
Human
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.027
organophosphate metabolic processGO:00196373700.026
Human
growthGO:00400071650.026
cellular response to nitrogen compoundGO:19016992100.026
positive regulation of molecular functionGO:00440932300.026
biological adhesionGO:00226101100.026
organonitrogen compound biosynthetic processGO:19015661670.025
gland developmentGO:00487321550.025
negative regulation of cellular biosynthetic processGO:00313271610.025
axonogenesisGO:0007409710.025
purine containing compound metabolic processGO:00725212530.025
Human
regulation of protein localizationGO:0032880810.025
regulation of purine nucleotide metabolic processGO:19005421150.025
response to monosaccharideGO:00342841590.024
cytoskeleton dependent cytokinesisGO:006164020.024
embryonic pattern specificationGO:000988010.024
regulation of intracellular signal transductionGO:19025312180.024
nucleoside phosphate metabolic processGO:00067532830.024
Human
gtp metabolic processGO:0046039720.023
Human
negative regulation of apoptotic processGO:00430661810.023
cell cycleGO:00070491010.023
Human
positive regulation of purine nucleotide metabolic processGO:1900544910.023
positive regulation of response to stimulusGO:00485842850.023
Human
regulation of cellular amino acid metabolic processGO:000652120.023
behaviorGO:00076102050.023
nucleotide catabolic processGO:00091661390.023
Human
cell fate determinationGO:000170920.023
positive regulation of cellular amino acid metabolic processGO:004576410.023
regulation of cell projection organizationGO:00313441750.023
cellular macromolecule localizationGO:00707271220.023
synaptic vesicle transportGO:0048489230.022
ribonucleotide catabolic processGO:00092611360.022
Human
tissue developmentGO:00098882520.022
neuron deathGO:00709971270.022
regulation of cellular ketone metabolic processGO:0010565270.022
positive regulation of cellular amine metabolic processGO:003324030.022
regulation of locomotionGO:00400121480.022
negative regulation of nucleic acid templated transcriptionGO:19035071170.022
purine nucleoside triphosphate catabolic processGO:00091461220.022
Human
purine ribonucleoside metabolic processGO:00461281680.022
Human
negative regulation of signalingGO:00230571570.021
vesicle docking involved in exocytosisGO:000690440.021
multicellular organism growthGO:003526410.021
ribonucleoside triphosphate metabolic processGO:00091991410.021
Human
regulation of endocytosisGO:0030100420.021
nucleobase containing compound catabolic processGO:00346551520.021
Human
positive regulation of nervous system developmentGO:00519621780.021
cellular ion homeostasisGO:00068731840.021
defense responseGO:00069521940.021
guanosine containing compound metabolic processGO:1901068740.021
Human
regulation of synaptic plasticityGO:0048167700.021
reproductive structure developmentGO:00486081280.021
regulation of calcium ion dependent exocytosisGO:0017158110.021
purine nucleoside triphosphate metabolic processGO:00091441410.020
Human
proteolysisGO:00065081750.020
negative regulation of nucleobase containing compound metabolic processGO:00459341530.020
establishment of synaptic vesicle localizationGO:0097480230.020
anion transportGO:00068201780.020
regulation of gtpase activityGO:0043087570.020
chromatin organizationGO:0006325340.020
nucleotide metabolic processGO:00091172790.020
Human
regulation of anatomical structure sizeGO:00900661350.019
response to growth factorGO:00708481890.019
purine nucleoside catabolic processGO:00061521240.019
Human
response to nutrientGO:00075842480.019
positive regulation of cell developmentGO:00107201760.019
negative regulation of molecular functionGO:00440921330.019
regulation of anion transportGO:0044070430.019
regulation of ion transportGO:00432692450.019
gliogenesisGO:0042063930.019
positive regulation of protein phosphorylationGO:00019341350.019
Human
axon cargo transportGO:000808810.019
small gtpase mediated signal transductionGO:0007264360.019
Human
single organism cellular localizationGO:19025801020.019
positive regulation of nucleotide catabolic processGO:0030813530.019
positive regulation of transcription dna templatedGO:00458931970.018
neuron neuron synaptic transmissionGO:0007270600.018
cell type specific apoptotic processGO:00972851340.018
cellular response to endogenous stimulusGO:00714953770.018
positive regulation of protein modification processGO:00314011420.018
Human
regulation of embryonic developmentGO:004599520.018
regulation of synaptic transmissionGO:00508041410.018
axis specificationGO:000979840.018
positive regulation of protein metabolic processGO:00512471780.018
Human
negative regulation of phosphate metabolic processGO:0045936800.018
regulation of neuron apoptotic processGO:0043523830.018
positive regulation of multicellular organismal processGO:00512403870.018
positive regulation of apoptotic processGO:00430651540.018
positive regulation of neuron differentiationGO:00456661260.018
agingGO:00075682410.018
positive regulation of nucleic acid templated transcriptionGO:19035081970.018
ion transmembrane transportGO:00342203650.017
reproductive system developmentGO:00614581280.017
ribonucleotide metabolic processGO:00092592310.017
Human
positive regulation of cell deathGO:00109421840.017
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.017
regulation of cellular catabolic processGO:00313291010.017
epithelial cell differentiationGO:0030855710.017
positive regulation of nucleotide metabolic processGO:0045981910.017
cation transportGO:00068123820.017
organic cyclic compound catabolic processGO:19013611750.017
Human
negative regulation of macromolecule biosynthetic processGO:00105581480.017
cellular ketone metabolic processGO:0042180510.016
vesicle dockingGO:004827850.016
positive regulation of rna biosynthetic processGO:19026801970.016
negative regulation of nervous system developmentGO:0051961790.016
response to external biotic stimulusGO:00432072210.016
regulation of cell motilityGO:20001451310.016
single organism biosynthetic processGO:00447113420.016
positive regulation of rna metabolic processGO:00512542030.016
synaptic vesicle endocytosisGO:004848840.016
positive regulation of developmental processGO:00510942830.016
glycosyl compound metabolic processGO:19016571820.016
Human
response to inorganic substanceGO:00100353770.016
response to glucoseGO:00097491360.015
response to axon injuryGO:0048678590.015
organic anion transportGO:00157111320.015
regulation of cellular component biogenesisGO:0044087860.015
regulation of membrane potentialGO:00423911100.015
synaptic vesicle docking involved in exocytosisGO:001608120.015
dendrite developmentGO:0016358720.015
dna metabolic processGO:0006259960.015
positive regulation of cell communicationGO:00106472710.015
Human
response to lipopolysaccharideGO:00324961910.015
regulation of system processGO:00440572080.015
taxisGO:0042330670.015
nucleoside phosphate catabolic processGO:19012921400.015
Human
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.015
negative regulation of cell differentiationGO:0045596990.015
chemical homeostasisGO:00488782920.015
negative regulation of protein metabolic processGO:00512481140.015
regulation of synapse maturationGO:009012820.015
positive regulation of cell projection organizationGO:00313461110.015
chromatin assembly or disassemblyGO:000633310.015
response to purine containing compoundGO:00140741260.015
regulation of ion transmembrane transportGO:00347651210.015
cell growthGO:00160491040.015
receptor mediated endocytosisGO:0006898420.015
organophosphate biosynthetic processGO:00904071430.015
nucleoside catabolic processGO:00091641260.015
Human
negative regulation of cell communicationGO:00106481580.015
negative regulation of cell developmentGO:0010721820.015
male gamete generationGO:0048232990.014
negative regulation of phosphorus metabolic processGO:0010563800.014
negative regulation of transportGO:00510511360.014
nucleoside triphosphate catabolic processGO:00091431230.014
Human
neurotransmitter secretionGO:0007269330.014
regulation of rab protein signal transductionGO:003248330.014
cytoskeleton organizationGO:00070101110.014
spindle organizationGO:000705120.014
organelle localizationGO:0051640550.014
positive regulation of neuron projection developmentGO:0010976990.014
cellular response to peptideGO:19016531330.014
neuromuscular synaptic transmissionGO:000727420.014
response to light stimulusGO:0009416520.014
guanosine containing compound catabolic processGO:1901069710.014
Human
response to oxidative stressGO:00069791860.014
negative regulation of rna metabolic processGO:00512531230.014
protein localization to membraneGO:0072657360.014
nitrogen compound transportGO:00717052290.014
ribonucleoside metabolic processGO:00091191740.014
Human
negative regulation of response to stimulusGO:00485851550.014
spermatogenesisGO:0007283990.014
lipid storageGO:001991510.014
circulatory system processGO:00030131830.014
regenerationGO:00310991630.014
salivary gland developmentGO:000743130.014
regulation of body fluid levelsGO:0050878900.014
regulation of nucleotide metabolic processGO:00061401170.014
regulation of nucleoside metabolic processGO:0009118660.014
response to transition metal nanoparticleGO:19902671220.014
rna localizationGO:000640340.014
negative regulation of developmental processGO:00510931250.014
receptor internalizationGO:0031623140.014
actin filament based processGO:0030029860.014
transmembrane transportGO:00550854120.014
macromolecule catabolic processGO:0009057580.014
response to peptideGO:19016522920.013
cellular response to insulin stimulusGO:0032869810.013
cytoplasmic transportGO:00164821150.013
signal transduction by phosphorylationGO:00230141440.013
Human
regulation of protein complex assemblyGO:0043254330.013
dna packagingGO:000632340.013
purine nucleotide biosynthetic processGO:0006164830.013
male mating behaviorGO:006017930.013
cellular response to lipidGO:00713962010.013
cardiovascular system developmentGO:00723581340.013
double strand break repairGO:000630210.013
monocarboxylic acid metabolic processGO:00327871520.013
epithelium developmentGO:0060429960.013
embryonic axis specificationGO:000057810.013
regulation of anatomical structure morphogenesisGO:00226031410.013
protein tetramerizationGO:0051262380.013
positive regulation of locomotionGO:00400171020.013
response to molecule of bacterial originGO:00022371940.013
regulation of neurotransmitter levelsGO:0001505420.013
response to corticosteroidGO:00319602350.013
chromosome organizationGO:0051276360.013
response to carbohydrateGO:00097431830.013
regulation of protein serine threonine kinase activityGO:0071900640.013
Human
negative regulation of cellular component organizationGO:0051129830.013
negative regulation of rna biosynthetic processGO:19026791180.012
cellular lipid metabolic processGO:00442552080.012
organic acid transportGO:00158491160.012
development of primary sexual characteristicsGO:00451371070.012
endomembrane system organizationGO:0010256480.012
immune system processGO:00023762040.012
g protein coupled receptor signaling pathwayGO:00071862420.012
chemotaxisGO:0006935660.012
regulation of neuron deathGO:19012141150.012
cyclic nucleotide biosynthetic processGO:0009190630.012
lens fiber cell differentiationGO:007030630.012
positive regulation of protein transportGO:0051222410.012
microvillus assemblyGO:003003320.012
cellular macromolecular complex assemblyGO:0034622580.012
chromatin modificationGO:0016568330.012
regulation of cell morphogenesis involved in differentiationGO:0010769720.012
cellular response to organonitrogen compoundGO:00714171970.012
negative regulation of neuron projection developmentGO:0010977460.012
olfactory behaviorGO:004204820.012
positive regulation of purine nucleotide catabolic processGO:0033123530.012
female pregnancyGO:00075651220.012
purine ribonucleotide biosynthetic processGO:0009152810.012
positive regulation of catabolic processGO:0009896780.012
regulation of catabolic processGO:00098941130.012
response to vitaminGO:00332731310.012
purine ribonucleoside triphosphate catabolic processGO:00092071220.012
Human
negative regulation of neurogenesisGO:0050768780.012
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
ras protein signal transductionGO:0007265290.011
Human
learning or memoryGO:0007611900.011
inflammatory responseGO:00069541500.011
cellular response to cytokine stimulusGO:00713451270.011
peptidyl tyrosine modificationGO:0018212720.011
mapk cascadeGO:00001651400.011
Human
regulation of cell growthGO:0001558850.011
response to biotic stimulusGO:00096072260.011
regulation of transmembrane transportGO:00347621220.011
regulation of purine nucleotide catabolic processGO:0033121650.011
wound healingGO:00420601220.011
regulation of axonogenesisGO:0050770370.011
positive regulation of ion transportGO:0043270940.011
regulation of cell cycleGO:0051726730.011
Human
dendritic spine organizationGO:0097061120.011
positive regulation of protein kinase activityGO:0045860730.011
Human
carbohydrate derivative catabolic processGO:19011361470.011
Human
anatomical structure formation involved in morphogenesisGO:0048646830.011
protein homooligomerizationGO:0051260910.011
cell cycle processGO:0022402570.011
negative regulation of cell proliferationGO:00082851190.011
negative regulation of signal transductionGO:0009968830.011
microtubule organizing center organizationGO:003102310.011
single organism nuclear importGO:1902593350.011
developmental process involved in reproductionGO:00030061590.011
regulation of cellular component movementGO:00512701500.011
ion homeostasisGO:00508012120.011
cellular response to growth factor stimulusGO:00713631620.011
organ morphogenesisGO:0009887750.011
detection of chemical stimulus involved in sensory perception of bitter tasteGO:000158040.011
ribonucleotide biosynthetic processGO:0009260850.010
peptidyl tyrosine phosphorylationGO:0018108720.010
gastrulationGO:000736920.010
blood vessel developmentGO:0001568690.010
regulation of nucleotide catabolic processGO:0030811650.010
adult locomotory behaviorGO:000834440.010
positive regulation of cell proliferationGO:00082842490.010
cytokine productionGO:0001816610.010
response to other organismGO:00517072200.010
response to bacteriumGO:00096172000.010
sensory perceptionGO:00076001010.010
cell cell signaling involved in cell fate commitmentGO:004516820.010
regulation of cell proliferationGO:00421273590.010
mitotic spindle organizationGO:000705220.010
meiotic cell cycle processGO:190304630.010
positive regulation of transferase activityGO:0051347810.010
Human
positive regulation of cellular component biogenesisGO:0044089550.010
positive regulation of rab gtpase activityGO:003285130.010
response to ketoneGO:19016541820.010

Madd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.028
central nervous system diseaseDOID:33100.020
disease of metabolismDOID:001466700.010