Rattus norvegicus

0 known processes

Nkx6-2

NK6 homeobox 2

Nkx6-2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to oxygen containing compoundGO:19017013860.191
Rat
positive regulation of multicellular organismal processGO:00512403870.146
regulation of synaptic transmissionGO:00508041410.124
regulation of nucleic acid templated transcriptionGO:19035063800.113
Rat
regulation of rna metabolic processGO:00512523910.111
Rat
cellular chemical homeostasisGO:00550822470.105
macromolecule localizationGO:00330362520.095
cell cell signalingGO:00072673350.094
Rat
response to inorganic substanceGO:00100353770.091
secretion by cellGO:00329402480.089
Rat
regulation of neuron differentiationGO:00456642080.088
single organism reproductive processGO:00447022970.081
regulation of multicellular organismal developmentGO:20000263760.080
rna biosynthetic processGO:00327743800.080
Rat
negative regulation of nucleic acid templated transcriptionGO:19035071170.079
Rat
response to extracellular stimulusGO:00099913800.079
cellular homeostasisGO:00197252520.079
regulation of neurogenesisGO:00507672470.078
regulation of nervous system developmentGO:00519602640.078
transcription dna templatedGO:00063513770.077
Rat
neuron differentiationGO:00301823680.073
Zebrafish
synaptic transmissionGO:00072682350.073
secretionGO:00469033070.072
Rat
regulation of rna biosynthetic processGO:20011413810.071
Rat
organic anion transportGO:00157111320.071
reproductionGO:00000032450.070
homeostatic processGO:00425923310.069
regulation of cell developmentGO:00602842630.068
response to nutrient levelsGO:00316673700.065
negative regulation of rna metabolic processGO:00512531230.064
Rat
organelle organizationGO:00069962660.062
chemical homeostasisGO:00488782920.061
intracellular signal transductionGO:00355563140.061
response to oxygen levelsGO:00704822650.060
central nervous system developmentGO:00074173110.059
Zebrafish
negative regulation of cellular metabolic processGO:00313242810.058
Rat
response to acid chemicalGO:00011012220.057
response to hexoseGO:00097461440.055
brain developmentGO:00074202470.055
multicellular organism reproductionGO:00325042330.054
cellular component assemblyGO:00226073600.054
regulation of transcription from rna polymerase ii promoterGO:00063572340.053
Rat
positive regulation of nitrogen compound metabolic processGO:00511733340.052
regulation of secretionGO:00510462240.052
Rat
response to corticosteroidGO:00319602350.052
positive regulation of nucleobase containing compound metabolic processGO:00459353190.051
negative regulation of transcription dna templatedGO:00458921160.051
Rat
negative regulation of gene expressionGO:00106291990.051
Rat
positive regulation of response to stimulusGO:00485842850.051
positive regulation of developmental processGO:00510942830.050
cellular response to stressGO:00335542690.049
response to biotic stimulusGO:00096072260.049
multicellular organismal reproductive processGO:00486092330.049
response to decreased oxygen levelsGO:00362932370.048
response to hypoxiaGO:00016662310.048
positive regulation of gene expressionGO:00106282440.048
regulation of hormone levelsGO:00108171870.047
Rat
regulation of cell proliferationGO:00421273590.047
immune system processGO:00023762040.046
response to glucocorticoidGO:00513842230.045
negative regulation of rna biosynthetic processGO:19026791180.044
Rat
reproductive processGO:00224143720.044
response to woundingGO:00096112540.044
nucleic acid templated transcriptionGO:00976593790.044
Rat
response to molecule of bacterial originGO:00022371940.044
protein complex biogenesisGO:00702712630.044
response to monosaccharideGO:00342841590.043
cellular response to nitrogen compoundGO:19016992100.043
Rat
negative regulation of signalingGO:00230571570.042
positive regulation of nervous system developmentGO:00519621780.042
regulation of transcription dna templatedGO:00063553740.042
Rat
response to estrogenGO:00436272320.041
regulation of cell differentiationGO:00455953200.041
negative regulation of metabolic processGO:00098923310.040
Rat
anatomical structure morphogenesisGO:00096532980.040
negative regulation of cellular biosynthetic processGO:00313271610.039
Rat
negative regulation of cell communicationGO:00106481580.039
positive regulation of transportGO:00510502450.039
Rat
regulation of secretion by cellGO:19035302080.039
Rat
positive regulation of transcription dna templatedGO:00458931970.038
cell projection organizationGO:00300303020.038
anion transportGO:00068201780.038
positive regulation of signalingGO:00230562700.037
Rat
regulation of molecular functionGO:00650093980.037
tissue developmentGO:00098882520.037
Zebrafish Rat
transcription from rna polymerase ii promoterGO:00063662520.037
Rat
negative regulation of macromolecule metabolic processGO:00106052600.037
Rat
response to glucoseGO:00097491360.036
response to temperature stimulusGO:0009266940.036
regulation of cellular component organizationGO:00511283680.036
catabolic processGO:00090563510.036
carbohydrate derivative metabolic processGO:19011353460.036
response to lipopolysaccharideGO:00324961910.035
nucleoside phosphate metabolic processGO:00067532830.035
positive regulation of cellular biosynthetic processGO:00313282950.035
negative regulation of biosynthetic processGO:00098901680.035
Rat
response to alkaloidGO:00432791320.034
Rat
positive regulation of cell differentiationGO:00455972170.034
protein complex assemblyGO:00064612630.034
response to oxidative stressGO:00069791860.034
regenerationGO:00310991630.034
cellular response to endogenous stimulusGO:00714953770.034
Rat
regulation of response to stressGO:00801341260.034
macromolecular complex subunit organizationGO:00439333390.033
programmed cell deathGO:00125013920.033
response to external biotic stimulusGO:00432072210.033
regulation of peptide secretionGO:0002791820.033
Rat
developmental process involved in reproductionGO:00030061590.033
cellular ion homeostasisGO:00068731840.032
response to metal ionGO:00100382530.032
response to ketoneGO:19016541820.032
response to radiationGO:00093141370.032
regulation of peptide transportGO:0090087870.032
Rat
neuron projection developmentGO:00311752730.032
rna metabolic processGO:00160704060.032
Rat
hormone secretionGO:00468791150.031
Rat
epithelial cell proliferationGO:0050673540.031
response to nutrientGO:00075842480.031
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.031
positive regulation of cell proliferationGO:00082842490.031
head developmentGO:00603222470.031
negative regulation of nitrogen compound metabolic processGO:00511721610.031
Rat
cellular component biogenesisGO:00440853680.030
cellular response to growth factor stimulusGO:00713631620.030
defense responseGO:00069521940.029
ribose phosphate biosynthetic processGO:0046390870.029
regulation of response to external stimulusGO:00321011060.029
regulation of intracellular signal transductionGO:19025312180.029
regulation of cellular component movementGO:00512701500.028
acid secretionGO:0046717480.028
regulation of catalytic activityGO:00507903040.028
cellular catabolic processGO:00442482950.028
response to ammonium ionGO:0060359710.028
nucleobase containing small molecule metabolic processGO:00550863160.028
positive regulation of biosynthetic processGO:00098913190.027
response to carbohydrateGO:00097431830.027
signal releaseGO:00230611450.027
Rat
regulation of phosphate metabolic processGO:00192203490.027
cellular lipid metabolic processGO:00442552080.027
positive regulation of neurogenesisGO:00507691650.027
regulation of protein metabolic processGO:00512462890.027
positive regulation of cellular component organizationGO:00511302000.027
regulation of programmed cell deathGO:00430673410.027
lipid metabolic processGO:00066292830.026
response to peptide hormoneGO:00434342780.026
Rat
response to growth factorGO:00708481890.026
negative regulation of transcription from rna polymerase ii promoterGO:0000122750.026
Rat
positive regulation of rna metabolic processGO:00512542030.026
negative regulation of transportGO:00510511360.026
organophosphate metabolic processGO:00196373700.026
protein complex subunit organizationGO:00718223020.026
negative regulation of macromolecule biosynthetic processGO:00105581480.025
Rat
organ regenerationGO:00311001010.025
cellular response to external stimulusGO:00714961180.025
single organism biosynthetic processGO:00447113420.025
cell morphogenesisGO:00009021420.025
cellular cation homeostasisGO:00300031800.025
g protein coupled receptor signaling pathwayGO:00071862420.025
reproductive structure developmentGO:00486081280.025
oxoacid metabolic processGO:00434362900.025
ion homeostasisGO:00508012120.025
negative regulation of nucleobase containing compound metabolic processGO:00459341530.025
Rat
response to bacteriumGO:00096172000.024
negative regulation of response to stimulusGO:00485851550.024
neuron developmentGO:00486662860.024
forebrain developmentGO:0030900980.024
gland developmentGO:00487321550.024
single organism catabolic processGO:00447122830.024
organic acid biosynthetic processGO:0016053830.023
mesoderm developmentGO:000749820.023
wnt signaling pathway planar cell polarity pathwayGO:006007120.023
nucleobase containing compound catabolic processGO:00346551520.023
organic acid metabolic processGO:00060822920.023
heterocycle catabolic processGO:00467001670.023
positive regulation of molecular functionGO:00440932300.023
metal ion homeostasisGO:00550651860.023
cell morphogenesis involved in differentiationGO:00009041190.023
response to toxic substanceGO:00096361330.023
positive regulation of cell developmentGO:00107201760.022
cellular response to lipidGO:00713962010.022
nitrogen compound transportGO:00717052290.022
Rat
positive regulation of rna biosynthetic processGO:19026801970.022
oxidation reduction processGO:00551143040.022
response to mechanical stimulusGO:00096121340.022
negative regulation of developmental processGO:00510931250.022
regulation of neuron projection developmentGO:00109751610.022
organophosphate catabolic processGO:00464341480.022
cellular response to peptide hormone stimulusGO:00713751200.022
Rat
regulation of signal transductionGO:00099663180.022
multi organism reproductive processGO:00447032620.022
single organism organelle organizationGO:19025891800.021
purine nucleotide metabolic processGO:00061632290.021
organic substance catabolic processGO:19015753160.021
epithelial cell differentiationGO:0030855710.021
Zebrafish Rat
hormone transportGO:00099141210.021
Rat
gamete generationGO:00072761240.021
regulation of anatomical structure morphogenesisGO:00226031410.021
peptide secretionGO:0002790860.021
Rat
regulation of peptide hormone secretionGO:0090276800.021
Rat
apoptotic processGO:00069153810.020
response to other organismGO:00517072200.020
purine containing compound metabolic processGO:00725212530.020
positive regulation of macromolecule biosynthetic processGO:00105572470.020
localization of cellGO:00516742020.020
reproductive system developmentGO:00614581280.020
regulation of lipid metabolic processGO:0019216680.020
amine metabolic processGO:0009308380.020
sexual reproductionGO:00199531480.020
positive regulation of nucleic acid templated transcriptionGO:19035081970.020
regulation of epithelial cell proliferationGO:0050678490.020
purine ribonucleotide metabolic processGO:00091502270.020
response to testosteroneGO:0033574550.020
protein oligomerizationGO:00512591910.020
regulation of insulin secretionGO:0050796650.019
Rat
carboxylic acid transportGO:00469421150.019
epithelium developmentGO:0060429960.019
Zebrafish Rat
aromatic compound catabolic processGO:00194391680.019
negative regulation of secretionGO:0051048820.019
locomotionGO:00400112370.019
positive regulation of homeostatic processGO:0032846490.019
regulation of cell projection organizationGO:00313441750.019
negative regulation of neurogenesisGO:0050768780.019
cellular ketone metabolic processGO:0042180510.019
vesicle mediated transportGO:00161921810.019
action potentialGO:0001508540.019
regulation of cellular protein metabolic processGO:00322682670.019
cellular response to organonitrogen compoundGO:00714171970.018
Rat
cellular amine metabolic processGO:0044106380.018
macromolecular complex assemblyGO:00650032730.018
ribose phosphate metabolic processGO:00196932350.018
rhythmic processGO:00485111560.018
regulation of phosphorus metabolic processGO:00511743490.018
positive regulation of secretionGO:00510471400.018
Rat
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.018
Rat
cellular response to organic cyclic compoundGO:00714072020.018
circulatory system processGO:00030131830.018
neuropeptide signaling pathwayGO:0007218290.018
organ morphogenesisGO:0009887750.018
positive regulation of phosphorus metabolic processGO:00105622620.017
organic cyclic compound catabolic processGO:19013611750.017
carbohydrate homeostasisGO:0033500750.017
peptide transportGO:0015833970.017
Rat
regulation of jun kinase activityGO:0043506100.017
axis specificationGO:000979840.017
regulation of ion transportGO:00432692450.017
dendrite developmentGO:0016358720.017
response to transition metal nanoparticleGO:19902671220.017
negative regulation of secretion by cellGO:1903531720.017
response to peptideGO:19016522920.017
Rat
non canonical wnt signaling pathwayGO:003556730.017
positive regulation of programmed cell deathGO:00430681570.017
cellular component morphogenesisGO:00329891550.017
divalent inorganic cation transportGO:00725111340.017
neuron projection morphogenesisGO:00488121220.017
intracellular transportGO:00469071850.016
cellular divalent inorganic cation homeostasisGO:00725031620.016
metal ion transportGO:00300012890.016
insulin secretionGO:0030073690.016
Rat
positive regulation of locomotionGO:00400171020.016
ribonucleotide metabolic processGO:00092592310.016
response to reactive oxygen speciesGO:00003021200.016
nucleotide metabolic processGO:00091172790.016
cell migrationGO:00164771970.016
glutamate secretionGO:0014047190.016
cation homeostasisGO:00550801950.016
agingGO:00075682410.016
calcium ion homeostasisGO:00550741620.016
single organism intracellular transportGO:19025821660.016
cellular response to peptideGO:19016531330.016
Rat
cellular response to abiotic stimulusGO:0071214850.016
positive regulation of protein metabolic processGO:00512471780.016
tube developmentGO:0035295890.016
metestrusGO:006021010.016
positive regulation of epithelial cell proliferationGO:0050679320.016
transmission of nerve impulseGO:0019226420.016
negative regulation of cell proliferationGO:00082851190.016
cellular macromolecule localizationGO:00707271220.015
anterior posterior pattern specificationGO:000995210.015
negative regulation of nervous system developmentGO:0051961790.015
regulation of synaptic plasticityGO:0048167700.015
organic acid transportGO:00158491160.015
establishment of protein localizationGO:00451841410.015
ras protein signal transductionGO:0007265290.015
response to vitaminGO:00332731310.015
olfactory behaviorGO:004204820.015
proteolysisGO:00065081750.015
tube formationGO:003514830.015
innate immune responseGO:0045087350.015
cell morphogenesis involved in neuron differentiationGO:00486671060.015
regulation of protein phosphorylationGO:00019321830.015
regulation of phosphorylationGO:00423252480.015
cellular component movementGO:00069282480.015
negative regulation of cell differentiationGO:0045596990.015
positive regulation of secretion by cellGO:19035321280.015
Rat
reactive oxygen species metabolic processGO:0072593370.015
regulation of mapk cascadeGO:00434081160.015
cell part morphogenesisGO:00329901230.015
positive regulation of phosphate metabolic processGO:00459372620.015
regulation of cellular localizationGO:00603412630.014
Rat
ion transmembrane transportGO:00342203650.014
positive regulation of apoptotic processGO:00430651540.014
small gtpase mediated signal transductionGO:0007264360.014
purine nucleotide biosynthetic processGO:0006164830.014
negative regulation of multicellular organismal processGO:00512412030.014
purine ribonucleoside triphosphate metabolic processGO:00092051400.014
peptide hormone secretionGO:0030072840.014
Rat
positive regulation of catalytic activityGO:00430851840.014
regulation of apoptotic processGO:00429813350.014
positive regulation of neuron differentiationGO:00456661260.014
response to estradiolGO:00323551640.014
cellular response to hormone stimulusGO:00328702470.014
Rat
cellular response to acid chemicalGO:0071229750.014
regulation of cell projection sizeGO:003253610.014
regulation of cellular amine metabolic processGO:003323880.014
protein phosphorylationGO:00064683450.014
small molecule biosynthetic processGO:00442831240.014
regulation of cellular amino acid metabolic processGO:000652120.014
purine containing compound catabolic processGO:00725231380.014
positive regulation of cellular component movementGO:00512721020.014
glucose homeostasisGO:0042593750.013
exocytosisGO:0006887600.013
male sex differentiationGO:0046661640.013
negative regulation of innate immune responseGO:004582440.013
positive regulation of catabolic processGO:0009896780.013
development of primary sexual characteristicsGO:00451371070.013
positive regulation of cellular amine metabolic processGO:003324030.013
regulation of nucleotide metabolic processGO:00061401170.013
positive regulation of cell communicationGO:00106472710.013
Rat
muscle contractionGO:0006936880.013
glutamate receptor signaling pathwayGO:0007215430.013
eye developmentGO:0001654500.013
neurological system process involved in regulation of systemic arterial blood pressureGO:000197630.013
glial cell differentiationGO:0010001650.013
regulation of ion homeostasisGO:2000021630.013
regulation of hydrolase activityGO:00513361430.013
regulation of homeostatic processGO:00328441010.013
negative regulation of apoptotic processGO:00430661810.013
negative regulation of cell deathGO:00605482290.013
regulation of anatomical structure sizeGO:00900661350.013
cation transportGO:00068123820.013
negative regulation of hormone secretionGO:0046888460.013
response to amino acidGO:0043200750.013
establishment of organelle localizationGO:0051656370.012
monocarboxylic acid transportGO:0015718520.012
regulation of catabolic processGO:00098941130.012
chromosome segregationGO:000705920.012
cellular nitrogen compound catabolic processGO:00442701630.012
spindle organizationGO:000705120.012
regulation of protein localizationGO:0032880810.012
sequestering of calcium ionGO:005120880.012
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188510.012
negative regulation of cell developmentGO:0010721820.012
amide transportGO:00428861050.012
Rat
cytoplasmic transportGO:00164821150.012
sex differentiationGO:00075481130.012
positive regulation of synaptic transmissionGO:0050806620.012
nucleotide biosynthetic processGO:0009165980.012
regulation of hormone secretionGO:00468831060.012
Rat
telencephalon developmentGO:0021537620.012
regulation of dendrite developmentGO:0050773590.012
carbohydrate derivative catabolic processGO:19011361470.012
neural crest cell differentiationGO:001403320.012
chemosensory behaviorGO:000763520.012
positive regulation of ion transportGO:0043270940.012
cellular response to carbohydrate stimulusGO:0071322720.012
regulation of cellular component biogenesisGO:0044087860.012
purine ribonucleoside metabolic processGO:00461281680.012
neurotransmitter secretionGO:0007269330.012
spermatogenesisGO:0007283990.012
actin filament based processGO:0030029860.012
nucleoside triphosphate metabolic processGO:00091411440.012
regulation of neuronal synaptic plasticityGO:0048168310.012
protein localizationGO:00081041910.012
multi multicellular organism processGO:00447061380.011
ribonucleoside metabolic processGO:00091191740.011
ribonucleoside catabolic processGO:00424541260.011
negative regulation of programmed cell deathGO:00430691830.011
maintenance of locationGO:0051235170.011
regulation of locomotionGO:00400121480.011
response to amineGO:0014075460.011
circulatory system developmentGO:00723591340.011
response to activityGO:0014823730.011
carboxylic acid metabolic processGO:00197522890.011
response to axon injuryGO:0048678590.011
regulation of membrane potentialGO:00423911100.011
response to ionizing radiationGO:0010212590.011
liver developmentGO:0001889900.011
cellular response to hexose stimulusGO:0071331650.011
lipid localizationGO:0010876620.011
response to ethanolGO:00454711620.011
purine ribonucleotide biosynthetic processGO:0009152810.011
male gamete generationGO:0048232990.011
reactive nitrogen species metabolic processGO:200105710.011
gonad developmentGO:00084061040.011
nucleoside phosphate catabolic processGO:19012921400.011
regulation of blood circulationGO:19035221100.011
carbohydrate derivative biosynthetic processGO:19011371240.011
multicellular organism growthGO:003526410.011
gastrulationGO:000736920.011
divalent metal ion transportGO:00708381320.011
regulation of neural precursor cell proliferationGO:2000177160.011
morphogenesis of embryonic epitheliumGO:001633130.011
glycosyl compound metabolic processGO:19016571820.011
regulation of cellular ketone metabolic processGO:0010565270.011
camp biosynthetic processGO:0006171470.011
cellular amino acid metabolic processGO:00065201070.011
purine nucleoside triphosphate metabolic processGO:00091441410.011
nucleoside metabolic processGO:00091161790.011
positive regulation of cytosolic calcium ion concentrationGO:00072041220.011
organic hydroxy compound transportGO:0015850770.011
mapk cascadeGO:00001651400.011
digestive system developmentGO:0055123410.011
rho protein signal transductionGO:0007266110.011
vesicle localizationGO:0051648330.010
ribonucleoside triphosphate metabolic processGO:00091991410.010
sensory organ developmentGO:0007423740.010
embryonic skeletal system developmentGO:004870630.010
cellular metal ion homeostasisGO:00068751720.010
endoplasmic reticulum organizationGO:000702910.010
regulation of system processGO:00440572080.010
positive regulation of cellular component biogenesisGO:0044089550.010
inflammatory responseGO:00069541500.010
positive regulation of cellular protein metabolic processGO:00322701670.010
hematopoietic progenitor cell differentiationGO:000224420.010
muscle system processGO:00030121150.010
growthGO:00400071650.010
regulation of organelle organizationGO:0033043800.010
lipid storageGO:001991510.010
regulation of neurotransmitter levelsGO:0001505420.010
reactive oxygen species biosynthetic processGO:190340980.010
response to insulinGO:00328681330.010

Nkx6-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:001466700.023