Rattus norvegicus

5 known processes

Phgdh

phosphoglycerate dehydrogenase

(Aliases: MGC105399)

Phgdh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carboxylic acid metabolic processGO:00197522890.176
alpha amino acid metabolic processGO:1901605710.145
organonitrogen compound biosynthetic processGO:19015661670.101
organic acid biosynthetic processGO:0016053830.093
single organism catabolic processGO:00447122830.090
cellular amino acid metabolic processGO:00065201070.086
response to nutrientGO:00075842480.085
oxoacid metabolic processGO:00434362900.082
small molecule biosynthetic processGO:00442831240.075
single organism biosynthetic processGO:00447113420.072
response to inorganic substanceGO:00100353770.069
cellular response to endogenous stimulusGO:00714953770.069
reproductive processGO:00224143720.062
coenzyme metabolic processGO:0006732860.061
organic acid metabolic processGO:00060822920.059
anion transportGO:00068201780.058
carboxylic acid transportGO:00469421150.055
cellular response to hormone stimulusGO:00328702470.053
organic substance catabolic processGO:19015753160.050
catabolic processGO:00090563510.050
branched chain amino acid transportGO:001580320.047
nucleic acid templated transcriptionGO:00976593790.047
intracellular signal transductionGO:00355563140.046
cellular component biogenesisGO:00440853680.046
response to extracellular stimulusGO:00099913800.046
response to mechanical stimulusGO:00096121340.045
nitrogen compound transportGO:00717052290.044
rna metabolic processGO:00160704060.044
cofactor metabolic processGO:0051186950.042
neuron differentiationGO:00301823680.041
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.040
cellular catabolic processGO:00442482950.040
organophosphate metabolic processGO:00196373700.039
organic anion transportGO:00157111320.038
nucleoside phosphate metabolic processGO:00067532830.038
carbohydrate derivative metabolic processGO:19011353460.037
cellular component assemblyGO:00226073600.037
response to peptideGO:19016522920.037
macromolecular complex subunit organizationGO:00439333390.036
response to toxic substanceGO:00096361330.036
negative regulation of cellular metabolic processGO:00313242810.036
negative regulation of metabolic processGO:00098923310.036
regulation of transcription dna templatedGO:00063553740.035
gland developmentGO:00487321550.035
response to nutrient levelsGO:00316673700.034
agingGO:00075682410.034
rna biosynthetic processGO:00327743800.033
positive regulation of nitrogen compound metabolic processGO:00511733340.033
organic acid transportGO:00158491160.032
nucleotide metabolic processGO:00091172790.031
amine metabolic processGO:0009308380.030
single organism carbohydrate catabolic processGO:0044724400.030
response to vitaminGO:00332731310.030
cellular response to stressGO:00335542690.030
transmembrane transportGO:00550854120.029
multi organism reproductive processGO:00447032620.029
regulation of rna metabolic processGO:00512523910.029
regulation of rna biosynthetic processGO:20011413810.028
cellular response to nitrogen compoundGO:19016992100.028
cellular amine metabolic processGO:0044106380.027
head developmentGO:00603222470.027
regulation of cellular ketone metabolic processGO:0010565270.027
negative regulation of macromolecule metabolic processGO:00106052600.026
regulation of protein metabolic processGO:00512462890.026
organelle organizationGO:00069962660.026
transcription dna templatedGO:00063513770.025
single organism reproductive processGO:00447022970.025
regulation of cellular protein metabolic processGO:00322682670.025
macromolecular complex assemblyGO:00650032730.025
response to carbohydrateGO:00097431830.025
regulation of nervous system developmentGO:00519602640.024
cell cell signalingGO:00072673350.024
cellular response to oxygen containing compoundGO:19017013860.024
regenerationGO:00310991630.024
ribose phosphate metabolic processGO:00196932350.024
regulation of multicellular organismal developmentGO:20000263760.024
negative regulation of gene expressionGO:00106291990.023
cation transportGO:00068123820.023
response to growth factorGO:00708481890.023
nucleobase containing small molecule metabolic processGO:00550863160.023
wound healingGO:00420601220.023
neuron developmentGO:00486662860.023
response to radiationGO:00093141370.022
regulation of cellular amino acid metabolic processGO:000652120.022
response to peptide hormoneGO:00434342780.022
single organism organelle organizationGO:19025891800.022
neuronal action potentialGO:0019228350.022
central nervous system developmentGO:00074173110.022
response to corticosteroidGO:00319602350.021
regulation of phosphorus metabolic processGO:00511743490.021
amino acid transportGO:0006865700.021
regulation of cell proliferationGO:00421273590.021
nicotinamide nucleotide metabolic processGO:0046496280.021
response to acid chemicalGO:00011012220.021
carbohydrate catabolic processGO:0016052400.021
reproductionGO:00000032450.020
regulation of cellular component organizationGO:00511283680.020
neurological system processGO:00508772190.020
carbohydrate metabolic processGO:00059751300.020
response to metal ionGO:00100382530.020
rhythmic processGO:00485111560.020
cell cycleGO:00070491010.020
protein complex assemblyGO:00064612630.020
negative regulation of signalingGO:00230571570.020
response to insulinGO:00328681330.020
response to ketoneGO:19016541820.019
cellular response to organonitrogen compoundGO:00714171970.019
regulation of cell differentiationGO:00455953200.019
regulation of nucleic acid templated transcriptionGO:19035063800.019
non canonical wnt signaling pathwayGO:003556730.019
metanephric comma shaped body morphogenesisGO:007227820.019
positive regulation of nucleic acid templated transcriptionGO:19035081970.019
carbohydrate derivative biosynthetic processGO:19011371240.019
regulation of molecular functionGO:00650093980.019
cellular response to fluid shear stressGO:007149840.019
response to glucocorticoidGO:00513842230.019
neuron projection developmentGO:00311752730.018
secretionGO:00469033070.018
anatomical structure morphogenesisGO:00096532980.018
programmed cell deathGO:00125013920.018
regulation of secretionGO:00510462240.018
negative regulation of biosynthetic processGO:00098901680.018
negative regulation of cellular biosynthetic processGO:00313271610.018
cellular amide metabolic processGO:0043603440.018
oxidation reduction processGO:00551143040.018
locomotionGO:00400112370.018
chromosome segregationGO:000705920.017
multicellular organismal signalingGO:0035637440.017
alpha amino acid biosynthetic processGO:1901607230.017
response to amino acidGO:0043200750.017
g protein coupled receptor signaling pathwayGO:00071862420.017
multicellular organism reproductionGO:00325042330.017
action potentialGO:0001508540.017
developmental growthGO:00485891000.017
ion transmembrane transportGO:00342203650.017
positive regulation of transcription dna templatedGO:00458931970.017
tissue developmentGO:00098882520.017
cell growthGO:00160491040.017
aspartate family amino acid biosynthetic processGO:000906740.017
positive regulation of nervous system developmentGO:00519621780.017
negative regulation of cell communicationGO:00106481580.017
multicellular organism growthGO:003526410.017
negative regulation of protein metabolic processGO:00512481140.016
response to bacteriumGO:00096172000.016
homeostatic processGO:00425923310.016
chemical homeostasisGO:00488782920.016
cellular ketone metabolic processGO:0042180510.016
positive regulation of cellular amine metabolic processGO:003324030.016
response to biotic stimulusGO:00096072260.016
heart morphogenesisGO:000300730.016
tetrahydrofolate metabolic processGO:004665390.016
multicellular organismal reproductive processGO:00486092330.016
protein oligomerizationGO:00512591910.016
cell projection organizationGO:00300303020.016
aspartate family amino acid metabolic processGO:0009066100.016
positive regulation of nucleobase containing compound metabolic processGO:00459353190.016
wnt signaling pathway calcium modulating pathwayGO:000722310.016
regulation of establishment of planar polarityGO:009017520.016
regulation of canonical wnt signaling pathwayGO:006082840.016
positive regulation of phosphorus metabolic processGO:00105622620.016
positive regulation of cellular amino acid metabolic processGO:004576410.016
regulation of secretion by cellGO:19035302080.015
negative regulation of macromolecule biosynthetic processGO:00105581480.015
female pregnancyGO:00075651220.015
regulation of cellular amine metabolic processGO:003323880.015
regulation of neuron differentiationGO:00456642080.015
cellular chemical homeostasisGO:00550822470.015
reproductive system developmentGO:00614581280.015
brain developmentGO:00074202470.015
signal releaseGO:00230611450.015
positive regulation of cell proliferationGO:00082842490.015
organophosphate biosynthetic processGO:00904071430.015
transmission of nerve impulseGO:0019226420.015
regulation of membrane potentialGO:00423911100.015
organic cyclic compound catabolic processGO:19013611750.014
response to cytokineGO:00340972150.014
regulation of cellular catabolic processGO:00313291010.014
protein complex subunit organizationGO:00718223020.014
cellular response to external stimulusGO:00714961180.014
negative regulation of apoptotic processGO:00430661810.014
myelinationGO:0042552390.014
response to lipopolysaccharideGO:00324961910.014
nucleobase containing compound catabolic processGO:00346551520.014
cellular modified amino acid metabolic processGO:0006575610.014
positive regulation of cell differentiationGO:00455972170.014
hepaticobiliary system developmentGO:0061008900.014
growthGO:00400071650.014
ensheathment of neuronsGO:0007272400.014
negative regulation of cell deathGO:00605482290.014
response to retinoic acidGO:0032526630.014
carbohydrate derivative catabolic processGO:19011361470.013
response to purine containing compoundGO:00140741260.013
response to hexoseGO:00097461440.013
response to woundingGO:00096112540.013
regulation of signal transductionGO:00099663180.013
response to transition metal nanoparticleGO:19902671220.013
ribose phosphate biosynthetic processGO:0046390870.013
regulation of growthGO:00400081050.013
aromatic compound catabolic processGO:00194391680.013
ion homeostasisGO:00508012120.013
regulation of phosphorylationGO:00423252480.013
reproductive structure developmentGO:00486081280.013
cell projection morphogenesisGO:00488581230.013
chromatin assembly or disassemblyGO:000633310.013
response to alkaloidGO:00432791320.013
multi multicellular organism processGO:00447061380.013
purine containing compound metabolic processGO:00725212530.013
cellular component movementGO:00069282480.013
macromolecule localizationGO:00330362520.013
response to estrogenGO:00436272320.013
purine ribonucleotide metabolic processGO:00091502270.012
cellular response to organic cyclic compoundGO:00714072020.012
sex differentiationGO:00075481130.012
tissue regenerationGO:0042246360.012
dna metabolic processGO:0006259960.012
negative regulation of programmed cell deathGO:00430691830.012
positive regulation of protein modification processGO:00314011420.012
positive regulation of molecular functionGO:00440932300.012
single organism carbohydrate metabolic processGO:00447231180.012
positive regulation of multicellular organismal processGO:00512403870.012
regulation of catalytic activityGO:00507903040.012
axon ensheathmentGO:0008366400.012
regulation of neuron projection developmentGO:00109751610.012
regulation of apoptotic processGO:00429813350.012
negative regulation of nitrogen compound metabolic processGO:00511721610.012
chromatin modificationGO:0016568330.012
leucine transportGO:001582020.012
nucleoside phosphate catabolic processGO:19012921400.012
protein complex biogenesisGO:00702712630.012
positive regulation of developmental processGO:00510942830.012
nucleoside metabolic processGO:00091161790.012
negative regulation of cellular component organizationGO:0051129830.012
chromosome organizationGO:0051276360.012
regulation of catabolic processGO:00098941130.012
positive regulation of phosphate metabolic processGO:00459372620.011
ribonucleotide metabolic processGO:00092592310.011
cellular modified amino acid biosynthetic processGO:0042398180.011
regulation of phosphate metabolic processGO:00192203490.011
amide biosynthetic processGO:0043604100.011
regulation of hormone secretionGO:00468831060.011
regulation of cell projection organizationGO:00313441750.011
circulatory system processGO:00030131830.011
establishment of tissue polarityGO:000716420.011
anion transmembrane transportGO:0098656770.011
response to oxidative stressGO:00069791860.011
regulation of neurogenesisGO:00507672470.011
cardiovascular system developmentGO:00723581340.011
nucleoside triphosphate metabolic processGO:00091411440.011
sexual reproductionGO:00199531480.011
small molecule catabolic processGO:0044282590.011
negative regulation of cell proliferationGO:00082851190.011
proteolysisGO:00065081750.011
axon developmentGO:0061564960.011
pteridine containing compound metabolic processGO:0042558140.011
negative regulation of transportGO:00510511360.011
negative regulation of cell cycle phase transitionGO:190198840.011
liver developmentGO:0001889900.011
small gtpase mediated signal transductionGO:0007264360.011
regulation of anatomical structure morphogenesisGO:00226031410.011
regulation of programmed cell deathGO:00430673410.011
positive regulation of nucleotide metabolic processGO:0045981910.011
negative regulation of nucleobase containing compound metabolic processGO:00459341530.011
cellular cation homeostasisGO:00300031800.011
protein phosphorylationGO:00064683450.011
positive regulation of rna biosynthetic processGO:19026801970.011
cytoskeleton dependent cytokinesisGO:006164020.011
gamete generationGO:00072761240.011
glycosyl compound metabolic processGO:19016571820.011
leucine importGO:006035610.011
organonitrogen compound catabolic processGO:19015651790.010
neural crest cell migrationGO:000175510.010
negative regulation of canonical wnt signaling pathwayGO:009009040.010
response to external biotic stimulusGO:00432072210.010
mitotic cell cycleGO:0000278490.010
positive regulation of phosphorylationGO:00423271770.010
regulation of hormone levelsGO:00108171870.010
cellular ion homeostasisGO:00068731840.010
purine nucleotide metabolic processGO:00061632290.010
regulation of developmental growthGO:0048638450.010
meiotic cell cycle processGO:190304630.010
positive regulation of biosynthetic processGO:00098913190.010
response to glucoseGO:00097491360.010
negative regulation of molecular functionGO:00440921330.010
cellular response to alcoholGO:0097306870.010
nucleotide biosynthetic processGO:0009165980.010
gastrulationGO:000736920.010
cell cycle processGO:0022402570.010
positive regulation of cell projection organizationGO:00313461110.010
nucleosome organizationGO:003472810.010
positive regulation of immune system processGO:0002684900.010

Phgdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:86300.014
disease of anatomical entityDOID:700.014
disease of cellular proliferationDOID:1456600.014
cancerDOID:16200.014
musculoskeletal system diseaseDOID:1700.013