Rattus norvegicus

106 known processes

Nppa

natriuretic peptide precursor A

(Aliases: RATANF,ANF,ANP,Pnd)

Nppa biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular localizationGO:00603412630.200
regulation of cell proliferationGO:00421273590.174
Rat
regulation of cellular component organizationGO:00511283680.154
response to extracellular stimulusGO:00099913800.145
cardiac muscle contractionGO:0060048270.138
circulatory system processGO:00030131830.128
homeostatic processGO:00425923310.116
Rat
nucleotide metabolic processGO:00091172790.106
regulation of phosphate metabolic processGO:00192203490.103
nucleoside phosphate biosynthetic processGO:19012931020.085
g protein coupled receptor signaling pathwayGO:00071862420.081
heart processGO:0003015570.078
tissue developmentGO:00098882520.077
regulation of catalytic activityGO:00507903040.070
ribose phosphate metabolic processGO:00196932350.069
regulation of molecular functionGO:00650093980.068
ribonucleotide metabolic processGO:00092592310.066
macromolecule localizationGO:00330362520.063
positive regulation of transportGO:00510502450.063
Rat
response to purine containing compoundGO:00140741260.061
heart contractionGO:0060047570.061
organophosphate metabolic processGO:00196373700.060
cellular component biogenesisGO:00440853680.059
purine nucleotide metabolic processGO:00061632290.059
positive regulation of multicellular organismal processGO:00512403870.059
Rat
multicellular organism reproductionGO:00325042330.057
regulation of hormone levelsGO:00108171870.056
positive regulation of secretionGO:00510471400.056
Rat
negative regulation of metabolic processGO:00098923310.056
regulation of secretion by cellGO:19035302080.056
chemical homeostasisGO:00488782920.054
Rat
regulation of phosphorus metabolic processGO:00511743490.053
nucleobase containing small molecule metabolic processGO:00550863160.052
cation transportGO:00068123820.052
cellular calcium ion homeostasisGO:00068741600.051
response to organophosphorusGO:00466831020.051
carbohydrate derivative metabolic processGO:19011353460.050
positive regulation of biosynthetic processGO:00098913190.049
negative regulation of macromolecule metabolic processGO:00106052600.048
positive regulation of signalingGO:00230562700.048
defense responseGO:00069521940.047
Rat
positive regulation of cytosolic calcium ion concentrationGO:00072041220.047
rna biosynthetic processGO:00327743800.046
lipid transportGO:0006869610.045
purine containing compound metabolic processGO:00725212530.045
synaptic transmissionGO:00072682350.045
nucleoside phosphate metabolic processGO:00067532830.045
cellular chemical homeostasisGO:00550822470.045
cellular component assemblyGO:00226073600.044
anatomical structure morphogenesisGO:00096532980.044
cytosolic calcium ion homeostasisGO:00514801400.044
regulation of multicellular organismal developmentGO:20000263760.044
neuron differentiationGO:00301823680.043
organelle organizationGO:00069962660.043
macromolecular complex subunit organizationGO:00439333390.042
purine containing compound biosynthetic processGO:0072522850.042
divalent inorganic cation homeostasisGO:00725071650.042
positive regulation of phosphate metabolic processGO:00459372620.042
secretion by cellGO:00329402480.041
multi organism reproductive processGO:00447032620.040
Mouse
negative regulation of cellular metabolic processGO:00313242810.040
regulation of apoptotic processGO:00429813350.040
blood circulationGO:00080151830.040
anion transportGO:00068201780.039
positive regulation of cellular biosynthetic processGO:00313282950.038
regulation of membrane potentialGO:00423911100.038
metal ion homeostasisGO:00550651860.038
Rat
monovalent inorganic cation transportGO:00156721720.038
regulation of system processGO:00440572080.038
Rat
peptide transportGO:0015833970.037
cell cell signalingGO:00072673350.037
positive regulation of nitrogen compound metabolic processGO:00511733340.037
metal ion transportGO:00300012890.036
positive regulation of cellular component organizationGO:00511302000.036
cell projection organizationGO:00300303020.035
regulation of growthGO:00400081050.035
regulation of cell differentiationGO:00455953200.034
positive regulation of cell differentiationGO:00455972170.034
positive regulation of phosphorus metabolic processGO:00105622620.034
positive regulation of catalytic activityGO:00430851840.033
regulation of potassium ion transportGO:0043266290.033
cellular homeostasisGO:00197252520.033
regulation of nucleic acid templated transcriptionGO:19035063800.032
ovulation cycleGO:0042698670.032
heart developmentGO:0007507720.032
Rat
organonitrogen compound biosynthetic processGO:19015661670.032
negative regulation of cell deathGO:00605482290.032
biological adhesionGO:00226101100.032
muscle system processGO:00030121150.031
Mouse
nitrogen compound transportGO:00717052290.031
secretionGO:00469033070.031
Rat
single organism catabolic processGO:00447122830.031
signal releaseGO:00230611450.030
purine ribonucleoside triphosphate catabolic processGO:00092071220.030
cellular cation homeostasisGO:00300031800.030
ion transmembrane transportGO:00342203650.030
positive regulation of developmental processGO:00510942830.030
inorganic ion transmembrane transportGO:00986602290.030
cellular response to oxygen containing compoundGO:19017013860.030
purine nucleoside triphosphate metabolic processGO:00091441410.030
regulation of cyclic nucleotide biosynthetic processGO:0030802450.030
cation homeostasisGO:00550801950.029
Rat
reproductive system developmentGO:00614581280.029
regulation of ion transportGO:00432692450.029
regulation of heart contractionGO:0008016480.029
protein phosphorylationGO:00064683450.029
negative regulation of transportGO:00510511360.029
ribonucleoside metabolic processGO:00091191740.029
cellular response to endogenous stimulusGO:00714953770.029
positive regulation of rna metabolic processGO:00512542030.028
ribonucleotide catabolic processGO:00092611360.028
response to lipopolysaccharideGO:00324961910.028
Rat
regulation of metal ion transportGO:00109591180.028
neuron developmentGO:00486662860.028
ribonucleoside catabolic processGO:00424541260.028
purine nucleoside catabolic processGO:00061521240.028
negative regulation of nucleobase containing compound metabolic processGO:00459341530.028
positive regulation of neurogenesisGO:00507691650.028
regulation of nervous system developmentGO:00519602640.027
hormone transportGO:00099141210.027
regulation of nucleotide metabolic processGO:00061401170.027
cellular metal ion homeostasisGO:00068751720.027
purine ribonucleotide metabolic processGO:00091502270.027
response to glucocorticoidGO:00513842230.026
negative regulation of ion transportGO:0043271510.026
regulation of peptide secretionGO:0002791820.026
response to campGO:0051591910.026
negative regulation of nitrogen compound metabolic processGO:00511721610.026
phospholipid metabolic processGO:0006644610.026
regulation of programmed cell deathGO:00430673410.026
amide transportGO:00428861050.026
negative regulation of cellular biosynthetic processGO:00313271610.026
regulation of phosphorylationGO:00423252480.026
positive regulation of cellular protein metabolic processGO:00322701670.025
cellular catabolic processGO:00442482950.025
hormone secretionGO:00468791150.025
regulation of cellular component movementGO:00512701500.025
nucleotide biosynthetic processGO:0009165980.025
regulation of muscle contractionGO:0006937530.025
regulation of rna metabolic processGO:00512523910.025
rhythmic processGO:00485111560.025
apoptotic processGO:00069153810.025
positive regulation of cell developmentGO:00107201760.025
potassium ion transportGO:0006813970.025
regulation of cellular protein metabolic processGO:00322682670.024
negative regulation of biosynthetic processGO:00098901680.024
heart morphogenesisGO:000300730.024
cellular divalent inorganic cation homeostasisGO:00725031620.024
regulation of protein metabolic processGO:00512462890.024
positive regulation of phosphorylationGO:00423271770.024
transmembrane transportGO:00550854120.024
single organism biosynthetic processGO:00447113420.024
striated muscle contractionGO:0006941440.023
cellular ketone metabolic processGO:0042180510.023
regulation of nucleotide catabolic processGO:0030811650.023
reproductive processGO:00224143720.023
Mouse
regulation of purine nucleotide catabolic processGO:0033121650.023
rna metabolic processGO:00160704060.023
purine containing compound catabolic processGO:00725231380.023
positive regulation of molecular functionGO:00440932300.023
nucleoside catabolic processGO:00091641260.023
aromatic compound catabolic processGO:00194391680.023
regulation of cell developmentGO:00602842630.023
negative regulation of cellular macromolecule biosynthetic processGO:20001131410.023
purine nucleoside metabolic processGO:00422781690.023
cellular response to stressGO:00335542690.023
lipid metabolic processGO:00066292830.023
response to carbohydrateGO:00097431830.022
regulation of purine nucleotide metabolic processGO:19005421150.022
cardiovascular system developmentGO:00723581340.022
Rat
glycosyl compound metabolic processGO:19016571820.022
response to transition metal nanoparticleGO:19902671220.022
guanosine containing compound metabolic processGO:1901068740.022
lipid localizationGO:0010876620.022
anatomical structure formation involved in morphogenesisGO:0048646830.022
neurological system processGO:00508772190.022
inorganic cation transmembrane transportGO:00986622020.022
response to nutrient levelsGO:00316673700.022
organic substance catabolic processGO:19015753160.022
positive regulation of response to stimulusGO:00485842850.022
purine ribonucleotide catabolic processGO:00091541360.022
insulin secretionGO:0030073690.022
cellular lipid metabolic processGO:00442552080.021
peptide secretionGO:0002790860.021
regulation of transcription dna templatedGO:00063553740.021
purine nucleotide biosynthetic processGO:0006164830.021
nucleic acid templated transcriptionGO:00976593790.021
phosphatidylinositol dephosphorylationGO:004685640.021
regulation of camp metabolic processGO:0030814430.021
axis specificationGO:000979840.020
positive regulation of protein metabolic processGO:00512471780.020
adult locomotory behaviorGO:000834440.020
organic anion transportGO:00157111320.020
regulation of hormone secretionGO:00468831060.020
amino acid transportGO:0006865700.020
nucleobase containing compound catabolic processGO:00346551520.020
transcription from rna polymerase ii promoterGO:00063662520.020
regulation of phosphatidylinositol dephosphorylationGO:006030410.020
female pregnancyGO:00075651220.020
Mouse
negative regulation of transcription dna templatedGO:00458921160.020
cellular component movementGO:00069282480.020
sensory organ developmentGO:0007423740.019
regulation of signal transductionGO:00099663180.019
positive regulation of protein modification processGO:00314011420.019
reproductionGO:00000032450.019
nucleoside metabolic processGO:00091161790.019
response to ammonium ionGO:0060359710.019
organophosphate catabolic processGO:00464341480.019
regulation of neuron differentiationGO:00456642080.019
regulation of nucleoside metabolic processGO:0009118660.019
regulation of cellular amino acid metabolic processGO:000652120.019
intracellular signal transductionGO:00355563140.019
regulation of kinase activityGO:00435491170.019
gastrulationGO:000736920.019
regulation of postsynaptic membrane potentialGO:0060078250.019
purine ribonucleoside triphosphate metabolic processGO:00092051400.019
cellular response to hormone stimulusGO:00328702470.019
negative regulation of apoptotic processGO:00430661810.019
reproductive structure developmentGO:00486081280.019
ion homeostasisGO:00508012120.019
Rat
carboxylic acid transportGO:00469421150.019
eye developmentGO:0001654500.019
protein oligomerizationGO:00512591910.019
cellular response to organic cyclic compoundGO:00714072020.019
fear responseGO:004259690.018
positive regulation of protein phosphorylationGO:00019341350.018
negative regulation of molecular functionGO:00440921330.018
organophosphate biosynthetic processGO:00904071430.018
divalent inorganic cation transportGO:00725111340.018
nucleotide catabolic processGO:00091661390.018
calcium ion homeostasisGO:00550741620.018
response to molecule of bacterial originGO:00022371940.018
Rat
response to hexoseGO:00097461440.018
response to growth factorGO:00708481890.018
cellular amine metabolic processGO:0044106380.018
regulation of synaptic transmissionGO:00508041410.018
response to glucoseGO:00097491360.018
positive regulation of cell proliferationGO:00082842490.018
positive regulation of secretion by cellGO:19035321280.018
behaviorGO:00076102050.018
regulation of catabolic processGO:00098941130.018
developmental process involved in reproductionGO:00030061590.018
organonitrogen compound catabolic processGO:19015651790.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
regulation of secretionGO:00510462240.018
Rat
negative regulation of phosphorus metabolic processGO:0010563800.018
head developmentGO:00603222470.018
positive regulation of cell communicationGO:00106472710.018
response to ethanolGO:00454711620.018
response to oxygen levelsGO:00704822650.017
positive regulation of nucleobase containing compound metabolic processGO:00459353190.017
amine metabolic processGO:0009308380.017
regulation of ion transmembrane transporter activityGO:0032412480.017
protein complex subunit organizationGO:00718223020.017
regulation of rna biosynthetic processGO:20011413810.017
ras protein signal transductionGO:0007265290.017
carbohydrate derivative catabolic processGO:19011361470.017
cation transmembrane transportGO:00986552630.017
positive regulation of nervous system developmentGO:00519621780.017
negative regulation of programmed cell deathGO:00430691830.017
neuron projection developmentGO:00311752730.017
feeding behaviorGO:0007631530.017
intracellular transportGO:00469071850.017
negative regulation of multicellular organismal processGO:00512412030.017
muscle contractionGO:0006936880.017
positive regulation of mapk cascadeGO:0043410920.016
negative regulation of response to stimulusGO:00485851550.016
positive regulation of intracellular signal transductionGO:19025331380.016
ribonucleotide biosynthetic processGO:0009260850.016
regulation of blood circulationGO:19035221100.016
catabolic processGO:00090563510.016
response to woundingGO:00096112540.016
regulation of cellular amine metabolic processGO:003323880.016
dephosphorylationGO:0016311980.016
ribonucleoside triphosphate catabolic processGO:00092031220.016
central nervous system developmentGO:00074173110.016
response to insulinGO:00328681330.016
response to corticosteroidGO:00319602350.016
regulation of response to stressGO:00801341260.016
regulation of anatomical structure morphogenesisGO:00226031410.016
purine ribonucleoside metabolic processGO:00461281680.016
protein transportGO:00150311320.016
forebrain developmentGO:0030900980.016
response to ketoneGO:19016541820.016
regulation of cardiac muscle contractionGO:0055117170.016
purine ribonucleotide biosynthetic processGO:0009152810.016
cellular amino acid metabolic processGO:00065201070.016
endocrine processGO:0050886320.015
purine nucleotide catabolic processGO:00061951360.015
multicellular organismal reproductive processGO:00486092330.015
negative regulation of rna metabolic processGO:00512531230.015
small gtpase mediated signal transductionGO:0007264360.015
regulation of transmembrane transporter activityGO:0022898490.015
regulation of mapk cascadeGO:00434081160.015
glycosyl compound catabolic processGO:19016581260.015
negative regulation of signalingGO:00230571570.015
response to external biotic stimulusGO:00432072210.015
Rat
organic acid transportGO:00158491160.015
response to alkaloidGO:00432791320.015
response to peptide hormoneGO:00434342780.015
positive regulation of purine nucleotide metabolic processGO:1900544910.015
response to peptideGO:19016522920.015
regulation of lipid metabolic processGO:0019216680.015
organic hydroxy compound transportGO:0015850770.015
regulation of transferase activityGO:00513381230.015
regulation of transcription from rna polymerase ii promoterGO:00063572340.014
regulation of protein modification processGO:00313991940.014
regulation of corticotropin secretionGO:005145970.014
transcription dna templatedGO:00063513770.014
response to monosaccharideGO:00342841590.014
carbohydrate derivative biosynthetic processGO:19011371240.014
single organism organelle organizationGO:19025891800.014
regulation of neuron projection developmentGO:00109751610.014
response to toxic substanceGO:00096361330.014
protein complex assemblyGO:00064612630.014
positive regulation of cellular amine metabolic processGO:003324030.014
regulation of response to external stimulusGO:00321011060.014
response to oxidative stressGO:00069791860.014
regulation of peptide transportGO:0090087870.014
lipid modificationGO:0030258520.014
positive regulation of programmed cell deathGO:00430681570.014
single organism reproductive processGO:00447022970.014
cellular ion homeostasisGO:00068731840.014
cell activationGO:0001775970.014
camp metabolic processGO:0046058630.014
hormone metabolic processGO:0042445690.014
positive regulation of gene expressionGO:00106282440.013
learning or memoryGO:0007611900.013
regulation of protein localizationGO:0032880810.013
positive regulation of macromolecule biosynthetic processGO:00105572470.013
positive regulation of cell deathGO:00109421840.013
nucleoside triphosphate catabolic processGO:00091431230.013
positive regulation of long term synaptic potentiationGO:190027340.013
brain developmentGO:00074202470.013
nucleoside phosphate catabolic processGO:19012921400.013
muscle structure developmentGO:0061061870.013
cellular component morphogenesisGO:00329891550.013
heterocycle catabolic processGO:00467001670.013
regulation of cell growthGO:0001558850.013
organ morphogenesisGO:0009887750.013
response to biotic stimulusGO:00096072260.013
Rat
regulation of transporter activityGO:0032409500.013
organic acid metabolic processGO:00060822920.013
enzyme linked receptor protein signaling pathwayGO:00071671160.013
response to histamineGO:003477630.013
muscle tissue developmentGO:0060537580.013
glycerophospholipid metabolic processGO:0006650470.013
regulation of intracellular transportGO:0032386650.013
programmed cell deathGO:00125013920.013
negative regulation of gene expressionGO:00106291990.013
regulation of hydrolase activityGO:00513361430.013
synaptic growth at neuromuscular junctionGO:005112410.013
cardiac muscle cell contractionGO:0086003100.013
sodium ion transportGO:0006814820.012
regulation of neurogenesisGO:00507672470.012
negative regulation of cell communicationGO:00106481580.012
calcium ion transmembrane transportGO:0070588700.012
macromolecular complex assemblyGO:00650032730.012
regulation of anatomical structure sizeGO:00900661350.012
cytoskeleton organizationGO:00070101110.012
calcium ion transportGO:00068161310.012
regulation of cell projection organizationGO:00313441750.012
carboxylic acid metabolic processGO:00197522890.012
gtp metabolic processGO:0046039720.012
regulation of intracellular signal transductionGO:19025312180.012
regulation of striated muscle contractionGO:0006942210.012
circulatory system developmentGO:00723591340.012
Rat
regulation of neuron deathGO:19012141150.012
response to other organismGO:00517072200.012
Rat
cellular response to organonitrogen compoundGO:00714171970.012
response to nutrientGO:00075842480.012
cytoplasmic transportGO:00164821150.012
positive regulation of growthGO:0045927550.012
regulation of ossificationGO:0030278320.012
gliogenesisGO:0042063930.012
gland developmentGO:00487321550.012
negative regulation of developmental processGO:00510931250.012
cellular response to growth factor stimulusGO:00713631620.012
protein localizationGO:00081041910.012
positive regulation of neuron differentiationGO:00456661260.012
cellular response to lipidGO:00713962010.012
rho protein signal transductionGO:0007266110.012
negative regulation of secretionGO:0051048820.011
regulation of calcium ion transmembrane transportGO:1903169180.011
cyclic nucleotide metabolic processGO:0009187800.011
regulation of neuronal synaptic plasticityGO:0048168310.011
developmental growthGO:00485891000.011
regulation of synaptic plasticityGO:0048167700.011
cell morphogenesis involved in differentiationGO:00009041190.011
actin filament based processGO:0030029860.011
response to estrogenGO:00436272320.011
protein complex biogenesisGO:00702712630.011
positive regulation of protein kinase activityGO:0045860730.011
ribose phosphate biosynthetic processGO:0046390870.011
response to bacteriumGO:00096172000.011
Rat
bmp signaling pathwayGO:003050940.011
olfactory learningGO:000835510.011
regulation of establishment of protein localizationGO:0070201690.011
regulation of organelle organizationGO:0033043800.011
antigen processing and presentationGO:001988220.011
regulation of muscle system processGO:0090257790.011
mesoderm developmentGO:000749820.011
cell cell signaling involved in cell fate commitmentGO:004516820.011
organic cyclic compound catabolic processGO:19013611750.011
vasculature developmentGO:0001944700.011
positive regulation of signal transductionGO:00099671750.011
cellular response to oxidative stressGO:0034599760.011
negative regulation of blood pressureGO:0045776290.011
negative regulation of phosphate metabolic processGO:0045936800.011
negative regulation of growthGO:0045926370.011
development of primary sexual characteristicsGO:00451371070.011
purine ribonucleoside catabolic processGO:00461301240.011
monocarboxylic acid transportGO:0015718520.011
regulation of peptide hormone secretionGO:0090276800.011
regulation of endocrine processGO:0044060210.011
negative regulation of purine nucleotide metabolic processGO:1900543230.011
neuron deathGO:00709971270.010
positive regulation of catabolic processGO:0009896780.010
protein heterooligomerizationGO:0051291890.010
cyclic purine nucleotide metabolic processGO:0052652620.010
regulation of protein kinase activityGO:00458591050.010
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.010
glial cell differentiationGO:0010001650.010
regulation of cellular component biogenesisGO:0044087860.010
response to radiationGO:00093141370.010
negative regulation of innate immune responseGO:004582440.010
regulation of tube sizeGO:0035150890.010
regulation of blood pressureGO:0008217830.010
cgmp biosynthetic processGO:0006182150.010
regenerationGO:00310991630.010
regulation of insulin secretionGO:0050796650.010
single organism behaviorGO:00447081300.010
positive regulation of transferase activityGO:0051347810.010
positive regulation of cellular amino acid metabolic processGO:004576410.010
regulation of cellular catabolic processGO:00313291010.010
regulation of gtpase activityGO:0043087570.010
eye morphogenesisGO:004859240.010
protein homooligomerizationGO:0051260910.010
regulation of protein transportGO:0051223680.010

Nppa disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye diseaseDOID:561400.024
eye and adnexa diseaseDOID:149200.024
disease of anatomical entityDOID:700.024
nervous system diseaseDOID:86300.024
sensory system diseaseDOID:005015500.024
retinal diseaseDOID:567900.012
heart diseaseDOID:11400.012
cardiovascular system diseaseDOID:128700.012
inherited metabolic disorderDOID:65500.011
disease of metabolismDOID:001466700.011
endocrine system diseaseDOID:2800.011