Rattus norvegicus

0 known processes

Hcls1

hematopoietic cell specific Lyn substrate 1

Hcls1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
immune system processGO:00023762040.502
Human
immune response regulating signaling pathwayGO:0002764190.288
activation of immune responseGO:0002253260.285
cell activationGO:0001775970.254
immune response activating signal transductionGO:0002757150.252
protein phosphorylationGO:00064683450.180
Human
regulation of phosphate metabolic processGO:00192203490.178
Human
immune responseGO:00069551040.167
response to biotic stimulusGO:00096072260.162
organophosphate metabolic processGO:00196373700.159
leukocyte cell cell adhesionGO:000715940.136
positive regulation of apoptotic processGO:00430651540.131
positive regulation of response to stimulusGO:00485842850.103
Human
nucleoside metabolic processGO:00091161790.102
transcription dna templatedGO:00063513770.100
Human
peptidyl tyrosine phosphorylationGO:0018108720.098
Human
positive regulation of biosynthetic processGO:00098913190.093
Human
organic acid metabolic processGO:00060822920.091
nucleobase containing small molecule metabolic processGO:00550863160.090
defense responseGO:00069521940.087
signal transduction by phosphorylationGO:00230141440.083
regulation of phosphorylationGO:00423252480.077
Human
cellular response to oxygen containing compoundGO:19017013860.076
positive regulation of phosphate metabolic processGO:00459372620.076
Human
positive regulation of phosphorylationGO:00423271770.076
Human
cellular component biogenesisGO:00440853680.073
Human
nucleic acid templated transcriptionGO:00976593790.072
Human
regulation of cellular component organizationGO:00511283680.071
Human
purine ribonucleoside triphosphate metabolic processGO:00092051400.069
regulation of immune system processGO:00026821230.069
Human
positive regulation of rna biosynthetic processGO:19026801970.068
Human
intracellular signal transductionGO:00355563140.068
Human
cellular nitrogen compound catabolic processGO:00442701630.067
regulation of cytokine productionGO:0001817560.065
regulation of intracellular signal transductionGO:19025312180.064
Human
regulation of cellular extravasationGO:000269120.064
lymphocyte activationGO:0046649430.063
response to woundingGO:00096112540.063
protein complex subunit organizationGO:00718223020.063
Human
positive regulation of cell communicationGO:00106472710.062
Human
positive regulation of nitrogen compound metabolic processGO:00511733340.061
Human
regulation of protein metabolic processGO:00512462890.060
Human
natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000242010.060
vesicle mediated transportGO:00161921810.059
Rat
positive regulation of signal transductionGO:00099671750.057
Human
cell migrationGO:00164771970.057
regulation of signal transductionGO:00099663180.057
Human
organonitrogen compound catabolic processGO:19015651790.057
pattern recognition receptor signaling pathwayGO:000222190.056
cellular response to stressGO:00335542690.056
nucleoside phosphate metabolic processGO:00067532830.055
carboxylic acid metabolic processGO:00197522890.055
regulation of catalytic activityGO:00507903040.053
fc receptor mediated stimulatory signaling pathwayGO:000243130.053
response to external biotic stimulusGO:00432072210.053
negative regulation of response to stimulusGO:00485851550.051
response to molecule of bacterial originGO:00022371940.051
ribose phosphate metabolic processGO:00196932350.051
regulation of phosphorus metabolic processGO:00511743490.051
Human
regulation of response to stressGO:00801341260.050
reproductionGO:00000032450.050
cellular component assemblyGO:00226073600.049
Human
regulation of cell differentiationGO:00455953200.048
Human
regulation of molecular functionGO:00650093980.048
monocarboxylic acid metabolic processGO:00327871520.048
protein localizationGO:00081041910.047
Human
rna biosynthetic processGO:00327743800.047
Human
response to other organismGO:00517072200.046
purine ribonucleoside catabolic processGO:00461301240.046
purine containing compound catabolic processGO:00725231380.045
purine nucleotide catabolic processGO:00061951360.045
rna metabolic processGO:00160704060.045
Human
regulation of protein phosphorylationGO:00019321830.045
Human
positive regulation of nucleobase containing compound metabolic processGO:00459353190.044
Human
cellular amine metabolic processGO:0044106380.044
cellular ketone metabolic processGO:0042180510.044
negative regulation of metabolic processGO:00098923310.044
multicellular organismal reproductive processGO:00486092330.044
ribonucleoside metabolic processGO:00091191740.044
positive regulation of cellular biosynthetic processGO:00313282950.043
Human
lipid metabolic processGO:00066292830.043
single organismal cell cell adhesionGO:0016337420.043
positive regulation of signalingGO:00230562700.043
Human
regulation of protein localizationGO:0032880810.043
Human
regulation of cellular protein metabolic processGO:00322682670.043
Human
regulation of rna metabolic processGO:00512523910.043
Human
regulation of protein modification processGO:00313991940.042
Human
nucleotide metabolic processGO:00091172790.042
positive regulation of cell migrationGO:0030335960.042
macromolecular complex assemblyGO:00650032730.041
Human
leukocyte migrationGO:0050900380.041
response to bacteriumGO:00096172000.041
salivary gland morphogenesisGO:000743510.041
ribonucleoside triphosphate metabolic processGO:00091991410.040
regulation of multicellular organismal developmentGO:20000263760.040
Human
positive regulation of macromolecule biosynthetic processGO:00105572470.040
Human
heterocycle catabolic processGO:00467001670.040
response to insulinGO:00328681330.040
positive regulation of molecular functionGO:00440932300.040
cellular catabolic processGO:00442482950.039
positive regulation of protein kinase activityGO:0045860730.039
regulation of apoptotic processGO:00429813350.039
Human
actin filament bundle assemblyGO:0051017190.039
purine ribonucleoside metabolic processGO:00461281680.039
neuron apoptotic processGO:0051402880.039
positive regulation of gene expressionGO:00106282440.039
Human
organelle organizationGO:00069962660.038
Human
anatomical structure morphogenesisGO:00096532980.038
cell adhesionGO:00071551100.038
glycosyl compound metabolic processGO:19016571820.038
multicellular organism reproductionGO:00325042330.037
protein transportGO:00150311320.037
Human
regulation of transcription dna templatedGO:00063553740.036
Human
reproductive processGO:00224143720.036
aromatic compound catabolic processGO:00194391680.036
response to reactive oxygen speciesGO:00003021200.036
leukocyte activationGO:0045321760.036
cell type specific apoptotic processGO:00972851340.036
Human
cell projection organizationGO:00300303020.035
response to mechanical stimulusGO:00096121340.035
purine containing compound metabolic processGO:00725212530.035
multi multicellular organism processGO:00447061380.034
cellular component movementGO:00069282480.034
regulation of cellular amine metabolic processGO:003323880.034
cellular amino acid metabolic processGO:00065201070.034
response to oxygen levelsGO:00704822650.034
cellular lipid metabolic processGO:00442552080.034
single organism reproductive processGO:00447022970.033
purine nucleotide metabolic processGO:00061632290.033
catabolic processGO:00090563510.033
amine metabolic processGO:0009308380.033
positive regulation of cellular amino acid metabolic processGO:004576410.033
immune response regulating cell surface receptor signaling pathwayGO:0002768100.032
regulation of cellular amino acid metabolic processGO:000652120.032
guanosine containing compound metabolic processGO:1901068740.032
ribonucleotide catabolic processGO:00092611360.032
positive regulation of cell deathGO:00109421840.032
regulation of immune responseGO:0050776550.032
response to oxidative stressGO:00069791860.032
regulation of cellular localizationGO:00603412630.031
Human
purine ribonucleotide metabolic processGO:00091502270.031
sexual reproductionGO:00199531480.031
reactive oxygen species metabolic processGO:0072593370.031
carbohydrate derivative metabolic processGO:19011353460.030
peptidyl amino acid modificationGO:00181931260.030
Human
positive regulation of smooth muscle cell proliferationGO:0048661510.030
negative regulation of cellular metabolic processGO:00313242810.030
programmed cell deathGO:00125013920.030
Human
multicellular organism growthGO:003526410.030
positive regulation of protein phosphorylationGO:00019341350.030
Human
purine ribonucleotide catabolic processGO:00091541360.030
cellular response to endogenous stimulusGO:00714953770.029
protein complex biogenesisGO:00702712630.029
Human
regulation of locomotionGO:00400121480.028
nucleobase containing compound catabolic processGO:00346551520.028
cellular response to lipidGO:00713962010.028
regulation of kinase activityGO:00435491170.028
positive regulation of nucleic acid templated transcriptionGO:19035081970.028
Human
wound healingGO:00420601220.028
regulation of system processGO:00440572080.027
ribonucleoside triphosphate catabolic processGO:00092031220.027
response to virusGO:0009615170.027
neuron projection developmentGO:00311752730.027
response to lipopolysaccharideGO:00324961910.027
multi organism reproductive processGO:00447032620.027
positive regulation of protein modification processGO:00314011420.027
Human
regulation of fc receptor mediated stimulatory signaling pathwayGO:006036830.026
localization of cellGO:00516742020.026
neuron deathGO:00709971270.026
cell motilityGO:00488702020.026
cellular macromolecule localizationGO:00707271220.026
Human
neuron differentiationGO:00301823680.026
negative regulation of signal transductionGO:0009968830.026
regulation of protein kinase activityGO:00458591050.026
organic cyclic compound catabolic processGO:19013611750.025
response to ammonium ionGO:0060359710.025
negative regulation of macromolecule metabolic processGO:00106052600.024
nucleoside phosphate catabolic processGO:19012921400.024
protein oligomerizationGO:00512591910.024
carbohydrate derivative catabolic processGO:19011361470.024
positive regulation of transportGO:00510502450.024
Human
positive regulation of multicellular organismal processGO:00512403870.024
Human
positive regulation of cellular amine metabolic processGO:003324030.024
gland developmentGO:00487321550.024
nucleotide catabolic processGO:00091661390.024
regulation of nucleic acid templated transcriptionGO:19035063800.024
Human
purine nucleoside metabolic processGO:00422781690.024
organic substance catabolic processGO:19015753160.024
single organism biosynthetic processGO:00447113420.024
purine nucleoside catabolic processGO:00061521240.023
cytokine biosynthetic processGO:004208930.023
regulation of cell developmentGO:00602842630.023
regulation of rna biosynthetic processGO:20011413810.023
Human
positive regulation of programmed cell deathGO:00430681570.023
negative regulation of cell communicationGO:00106481580.023
secretion by cellGO:00329402480.023
regulation of gtpase activityGO:0043087570.023
regulation of transcription from rna polymerase ii promoterGO:00063572340.023
Human
positive regulation of transferase activityGO:0051347810.023
positive regulation of gtpase activityGO:0043547470.023
positive regulation of protein metabolic processGO:00512471780.023
Human
response to peptidoglycanGO:003249410.022
gamete generationGO:00072761240.022
regulation of defense responseGO:0031347680.022
inflammatory responseGO:00069541500.022
oxoacid metabolic processGO:00434362900.022
macromolecule localizationGO:00330362520.022
Human
cellular response to acid chemicalGO:0071229750.022
cellular response to molecule of fungal originGO:007122610.022
negative regulation of rna biosynthetic processGO:19026791180.022
nucleoside triphosphate metabolic processGO:00091411440.022
positive regulation of neuron projection developmentGO:0010976990.022
single organism organelle organizationGO:19025891800.021
Human
cellular protein localizationGO:00346131220.021
Human
ribonucleoside catabolic processGO:00424541260.021
regulation of reactive oxygen species metabolic processGO:2000377260.021
regulation of cell motilityGO:20001451310.021
cellular response to biotic stimulusGO:0071216590.021
positive regulation of developmental processGO:00510942830.021
Human
nucleoside catabolic processGO:00091641260.021
response to peptide hormoneGO:00434342780.021
alcohol metabolic processGO:0006066770.021
regulation of cell proliferationGO:00421273590.021
macromolecular complex subunit organizationGO:00439333390.021
Human
regulation of neurogenesisGO:00507672470.021
negative regulation of immune response to tumor cellGO:000283820.020
positive regulation of defense responseGO:0031349370.020
neuron developmentGO:00486662860.020
single organism catabolic processGO:00447122830.020
regulation of cellular component movementGO:00512701500.020
cardiovascular system developmentGO:00723581340.020
negative regulation of biosynthetic processGO:00098901680.020
regulation of response to external stimulusGO:00321011060.020
cellular response to molecule of bacterial originGO:0071219560.020
response to acid chemicalGO:00011012220.020
glycosyl compound catabolic processGO:19016581260.019
positive regulation of phosphatidylinositol 3 kinase activityGO:004355220.019
actin filament organizationGO:0007015420.019
Human
regulation of platelet derived growth factor receptor signaling pathwayGO:001064020.019
positive regulation of phosphorus metabolic processGO:00105622620.019
Human
cellular response to external stimulusGO:00714961180.019
negative regulation of apoptotic processGO:00430661810.019
Human
negative regulation of signalingGO:00230571570.019
regulation of cellular ketone metabolic processGO:0010565270.019
purine ribonucleoside triphosphate catabolic processGO:00092071220.019
positive regulation of immune responseGO:0050778420.019
positive regulation of cell motilityGO:2000147970.019
regulation of transferase activityGO:00513381230.019
response to hypoxiaGO:00016662310.019
neurological system processGO:00508772190.019
homeostatic processGO:00425923310.019
locomotionGO:00400112370.018
positive regulation of neurogenesisGO:00507691650.018
developmental process involved in reproductionGO:00030061590.018
regulation of anatomical structure morphogenesisGO:00226031410.018
histamine production involved in inflammatory responseGO:000234930.018
response to toxic substanceGO:00096361330.018
regulation of nervous system developmentGO:00519602640.018
negative regulation of macromolecule biosynthetic processGO:00105581480.018
positive regulation of cellular component organizationGO:00511302000.018
cellular response to lipopolysaccharideGO:0071222550.018
regulation of b cell differentiationGO:004557710.018
small gtpase mediated signal transductionGO:0007264360.017
positive regulation of transcription dna templatedGO:00458931970.017
Human
positive regulation of secretion by cellGO:19035321280.017
nucleoside triphosphate catabolic processGO:00091431230.017
negative regulation of gene expressionGO:00106291990.017
regulation of mapk cascadeGO:00434081160.017
organophosphate catabolic processGO:00464341480.017
reactive nitrogen species metabolic processGO:200105710.017
smooth muscle cell migrationGO:0014909360.017
response to carbohydrateGO:00097431830.017
dephosphorylationGO:0016311980.017
agingGO:00075682410.017
innate immune response activating signal transductionGO:000275890.017
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:200124030.017
protein complex assemblyGO:00064612630.017
Human
t cell activationGO:0042110290.016
regulation of anatomical structure sizeGO:00900661350.016
Human
positive regulation of cell proliferationGO:00082842490.016
ras protein signal transductionGO:0007265290.016
regulation of hydrolase activityGO:00513361430.016
response to fatty acidGO:0070542650.016
regulation of neuron apoptotic processGO:0043523830.016
behaviorGO:00076102050.016
muscle system processGO:00030121150.016
positive regulation of angiogenesisGO:0045766280.016
single organism intracellular transportGO:19025821660.016
Human
insulin like growth factor receptor signaling pathwayGO:004800930.016
positive regulation of catalytic activityGO:00430851840.016
negative regulation of nitrogen compound metabolic processGO:00511721610.016
regulation of cellular component biogenesisGO:0044087860.015
Human
nitrogen compound transportGO:00717052290.015
immune response to tumor cellGO:000241830.015
apoptotic processGO:00069153810.015
Human
positive regulation of cellular component movementGO:00512721020.015
positive regulation of muscle contractionGO:0045933220.015
positive regulation of transcription from rna polymerase ii promoterGO:00459441480.015
Human
innate immune responseGO:0045087350.015
hormone secretionGO:00468791150.015
anion transportGO:00068201780.015
anatomical structure formation involved in morphogenesisGO:0048646830.015
regulation of programmed cell deathGO:00430673410.015
Human
positive regulation of immune system processGO:0002684900.015
Human
icosanoid metabolic processGO:0006690380.015
positive regulation of transcription factor import into nucleusGO:004299340.015
Human
mapk cascadeGO:00001651400.015
response to decreased oxygen levelsGO:00362932370.015
regulation of hormone levelsGO:00108171870.015
positive regulation of kinase activityGO:0033674770.015
ribonucleotide metabolic processGO:00092592310.015
membrane organizationGO:0061024940.015
organophosphate biosynthetic processGO:00904071430.014
purine ribonucleoside monophosphate metabolic processGO:0009167840.014
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell targetGO:000285910.014
platelet aggregationGO:007052740.014
establishment of protein localizationGO:00451841410.014
Human
response to molecule of fungal originGO:000223830.014
secretionGO:00469033070.014
hormone transportGO:00099141210.014
synaptic growth at neuromuscular junctionGO:005112410.014
regulation of cytokine secretionGO:0050707110.014
positive regulation of intracellular signal transductionGO:19025331380.014
Human
triglyceride homeostasisGO:007032820.014
defense response to gram positive bacteriumGO:005083020.014
gtp metabolic processGO:0046039720.014
organic acid transportGO:00158491160.014
vasculature developmentGO:0001944700.014
cell activation involved in immune responseGO:0002263160.014
single organism cellular localizationGO:19025801020.014
Human
transmission of nerve impulseGO:0019226420.014
negative regulation of signal transduction in absence of ligandGO:190109930.014
positive regulation of lipid kinase activityGO:009021820.014
regulation of nucleotide metabolic processGO:00061401170.014
cellular component morphogenesisGO:00329891550.014
regulation of cell migrationGO:00303341280.014
cellular response to nitrogen compoundGO:19016992100.014
cellular response to growth factor stimulusGO:00713631620.014
negative regulation of cellular biosynthetic processGO:00313271610.013
cellular carbohydrate metabolic processGO:0044262720.013
circulatory system developmentGO:00723591340.013
cellular response to reactive oxygen speciesGO:0034614550.013
skin morphogenesisGO:004358920.013
positive regulation of mapk cascadeGO:0043410920.013
cellular response to oxidative stressGO:0034599760.013
purine nucleoside monophosphate catabolic processGO:0009128550.013
brain developmentGO:00074202470.013
Rat
sequestering of metal ionGO:005123890.013
biological adhesionGO:00226101100.013
regulation of protein transportGO:0051223680.013
Human
purine nucleoside triphosphate metabolic processGO:00091441410.013
cellular response to organic cyclic compoundGO:00714072020.013
negative regulation of nucleic acid templated transcriptionGO:19035071170.013
negative regulation of rna metabolic processGO:00512531230.013
positive regulation of rna metabolic processGO:00512542030.012
Human
regulation of cell projection organizationGO:00313441750.012
rho protein signal transductionGO:0007266110.012
muscle cell migrationGO:0014812360.012
actin filament based processGO:0030029860.012
Human
regulation of neuron deathGO:19012141150.012
cellular response to retinoic acidGO:0071300270.012
b cell differentiationGO:003018320.012
negative regulation of neuron apoptotic processGO:0043524450.012
regulation of small gtpase mediated signal transductionGO:0051056480.012
regulation of neural precursor cell proliferationGO:2000177160.012
regulation of dna metabolic processGO:0051052600.012
regulation of cytokine biosynthetic processGO:004203530.012
membrane tubulationGO:009732020.012
regulation of leukocyte proliferationGO:0070663260.012
regulation of cellular component sizeGO:0032535510.012
Human
response to extracellular stimulusGO:00099913800.012
monosaccharide metabolic processGO:0005996610.012
response to hydrogen peroxideGO:0042542890.012
cellular response to hormone stimulusGO:00328702470.012
hexose metabolic processGO:0019318580.012
carbohydrate metabolic processGO:00059751300.012
regulation of hormone secretionGO:00468831060.012
regulation of alkaline phosphatase activityGO:001069220.012
epidermal growth factor receptor signaling pathwayGO:0007173230.012
negative regulation of phosphate metabolic processGO:0045936800.012
rna localizationGO:000640340.012
endomembrane system organizationGO:0010256480.012
unsaturated fatty acid metabolic processGO:0033559390.012
response to nutrient levelsGO:00316673700.011
positive regulation of secretionGO:00510471400.011
regulation of cytoskeleton organizationGO:0051493490.011
Human
protein homooligomerizationGO:0051260910.011
cellular process involved in reproduction in multicellular organismGO:0022412350.011
guanosine containing compound catabolic processGO:1901069710.011
cellular response to mechanical stimulusGO:0071260480.011
sensory perception of painGO:0019233730.011
natural killer cell mediated immune response to tumor cellGO:000242310.011
cell cell signalingGO:00072673350.011
response to tumor cellGO:000234740.011
epithelial cell migrationGO:0010631190.011
olfactory learningGO:000835510.011
positive regulation of neuron differentiationGO:00456661260.011
positive regulation of map kinase activityGO:0043406460.011
regulation of establishment of protein localizationGO:0070201690.011
Human
negative regulation of natural killer cell mediated immune response to tumor cellGO:000285610.011
negative regulation of programmed cell deathGO:00430691830.011
Human
positive regulation of smooth muscle cell migrationGO:0014911270.011
negative regulation of protein metabolic processGO:00512481140.011
lipid storageGO:001991510.011
phospholipid metabolic processGO:0006644610.011
antigen receptor mediated signaling pathwayGO:005085110.011
monocarboxylic acid biosynthetic processGO:0072330480.011
cellular response to organonitrogen compoundGO:00714171970.011
negative regulation of phosphorus metabolic processGO:0010563800.011
regulation of vasculature developmentGO:1901342440.011
regulation of smooth muscle cell proliferationGO:0048660750.011
salivary gland developmentGO:000743130.011
actin cytoskeleton organizationGO:0030036730.011
Human
small molecule biosynthetic processGO:00442831240.010
response to retinoic acidGO:0032526630.010
positive regulation of cellular protein metabolic processGO:00322701670.010
Human
response to ethanolGO:00454711620.010
negative regulation of natural killer cell mediated immunityGO:000271640.010
activation of innate immune responseGO:000221890.010
positive regulation of hydrolase activityGO:0051345860.010
regulation of smooth muscle contractionGO:0006940290.010
positive regulation of dna metabolic processGO:0051054390.010
cell junction maintenanceGO:003433110.010
positive regulation of innate immune responseGO:0045089110.010
blood coagulationGO:0007596260.010
regulation of neuron projection developmentGO:00109751610.010
t cell migrationGO:007267820.010
response to ketoneGO:19016541820.010
signal releaseGO:00230611450.010

Hcls1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
primary immunodeficiency diseaseDOID:61200.048
hematopoietic system diseaseDOID:7400.048
b cell deficiencyDOID:211500.048
disease of anatomical entityDOID:700.048
blood protein diseaseDOID:62000.048
immune system diseaseDOID:291400.048
agammaglobulinemiaDOID:258300.048
musculoskeletal system diseaseDOID:1700.013